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Which drugs are most reported with Tumour lysis syndrome?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 8,622 reports · 322 co-occurring drugs

As of the last recalculation, Tumour Lysis Syndrome appears in 8,622 FAERS reports alongside 322 co-occurring drug terms. The strongest observed disproportionality signal is VENETOCLAX (PRR 51.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Venetoclax	1,145	51.6	52.6
Obinutuzumab	325	49.5	50.5
Azacitidine For	309	42.5	43.2
Azacitidine	391	33.3	33.7
Bendamustine Hydrochloride	147	30.1	30.5
Febuxostat Tablets 40 Mg	125	30.1	30.5
Febuxostat Tablets 80 Mg	125	30.1	30.5
Bendamustine Hcl	182	28.9	29.3
Etoposide	769	27.6	27.9
Cytarabine	594	25.6	25.8
Doxorubicin	824	24.6	24.8
Polatuzumab Vedotin	94	23.5	23.7
Acalabrutinib	116	23.4	23.6
Vincristine Sulfate	264	22.4	22.6
Ifosfamide	195	22.4	22.6
Carfilzomib	242	21.2	21.4
Blinatumomab	89	20.8	21.0
Doxorubicin Hydrochloride	260	19.8	19.9
Cyclophosphamide Injection, Solution	1,250	19.8	19.9
Cyclophosphamide	1,250	19.8	19.9
Cyclophosphamide For Injection	1,250	19.8	19.9
Hydroxyurea	168	19.5	19.7
Posaconazole Delayed-Release	87	19.3	19.5
Micafungin Sodium	66	18.9	19.1
Febuxostat	129	18.8	19.0
Rituximab	1,384	18.6	18.8
Posaconazole	106	15.9	16.0
Mesna	51	14.7	14.8
Allopurinol	860	14.6	14.7
Mesna Injection	48	14.1	14.2
Fludarabine Phosphate	224	14.1	14.2
Brentuximab Vedotin	59	14.0	14.1
Dexamethasone Sodium Phosphate	57	13.6	13.7
Cisplatin	414	13.4	13.5
Bleomycin Sulfate	56	13.2	13.2
Daratumumab	210	13.0	13.0
Bortezomib	448	12.7	12.8
Filgrastim	173	11.3	11.4
Axicabtagene Ciloleucel	46	11.3	11.4
Encorafenib	46	11.3	11.3
Ibrutinib	359	11.2	11.2
Dexamethasone 1.5 Mg	1,166	11.0	11.0
Pegaspargase	55	10.9	11.0
Dexamethasone	1,166	10.8	10.9
Cefepime Hydrochloride	71	10.7	10.8
Oxaliplatin	318	10.7	10.7
Gemcitabine Hydrochloride	227	10.6	10.6
Gemcitabine	166	10.4	10.4
Cefepime	61	10.3	10.4
Leucovorin Calcium	81	10.3	10.4
Sodium Bicarbonate	97	10.2	10.2
Sodium Bicarbonate Injection,	97	10.2	10.2
Meropenem	132	10.1	10.1
Hydrocortisone Sodium Succinate	37	9.5	9.6
Carboplatin	460	9.2	9.2
Granisetron Hydrochloride	39	9.1	9.1
Melphalan	80	8.6	8.6
Piperacillin Sodium,Tazobactam Sodium	91	8.4	8.4
Melphalan Hydrochloride	84	8.2	8.2
Fluconazole	230	8.1	8.1
Fluorouracil Cream, 0.5%	249	8.1	8.1
Calcium Gluconate	40	8.0	8.1
Phytonadione	28	8.0	8.0
Fluorouracil	249	8.0	8.0
Dextrose	42	7.7	7.8
Dextrose Monohydrate	42	7.6	7.6
Lenvatinib	102	7.6	7.6
Piperacillin And Tazobactam	38	7.2	7.2
Piperacillin Sodium And Tazobactam Sodium	58	7.2	7.2
Fosaprepitant Dimeglumine	40	7.1	7.1
Acyclovir	321	7.0	7.0
Norepinephrine	30	6.8	6.8
Aprepitant	50	6.6	6.6
Prednisolone	468	6.6	6.6
Prednisolone Oral	468	6.6	6.6
Prednisolone Oral Solution	468	6.6	6.6
Valacyclovir	111	6.5	6.5
Voriconazole Injection	58	6.5	6.5
Itraconazole	31	6.4	6.4
Alemtuzumab	50	6.3	6.3
Voriconazole	78	6.2	6.3
Norepinephrine Bitartrate	37	6.2	6.2
Sulfamethoxazole And Trimethoprim	212	6.2	6.2
Valacyclovir Hydrochloride	177	6.2	6.2
Nevirapine	23	6.2	6.2
Atezolizumab	98	6.2	6.2
Imatinib	43	5.9	5.9
Magnesium Sulfate In Water For	31	5.9	5.9
Sorafenib	50	5.8	5.9
Magnesium Sulfate Heptahydrate	31	5.8	5.8
Magnesium Sulfate	31	5.8	5.8
Paclitaxel (Aibumin-Bound)	187	5.6	5.6
Ganciclovir Sodium	24	5.5	5.5
Dimenhydrinate	24	5.4	5.5
Efavirenz	25	5.4	5.4
Granisetron	23	5.3	5.3
Thiamine Hydrochloride	27	5.3	5.3
Paclitaxel	211	5.2	5.3
Polyethylene Glycol	23	5.1	5.1
Ganciclovir	21	5.0	5.0
Atazanavir	29	4.9	4.9
Ipilimumab	85	4.8	4.8
Methylprednisolone Sodium Succinate	91	4.8	4.8
Ondansetron	210	4.7	4.7
Ondansetron Tablets	210	4.7	4.7
Zidovudine	26	4.7	4.7
Thalidomide	70	4.6	4.6
Vancomycin	108	4.6	4.6
Raltegravir	31	4.5	4.6
Prednisone	863	4.5	4.5
Magnesium Oxide	77	4.5	4.5
Anti-Itch	122	4.4	4.4
Anti-Pruritic	122	4.4	4.4
Antipruritic (Anti-Itch)	122	4.4	4.4
Cool Relief Gel With Aloe	122	4.4	4.4
Drs. Hydrocortisone	122	4.4	4.4
Hydrocortisone Continuous Spray	122	4.4	4.4
Hydrocortisone Spray	122	4.4	4.4
Anti-Itch Cream	122	4.4	4.4
Hydrocortisone Lotion	122	4.4	4.4
Hydrocortisone Cream 1%	122	4.4	4.4
Hydrocortisone Cream 1/2%	122	4.4	4.4
Hydrocortisone 1%	122	4.4	4.4
Hydrocortisone Cream	122	4.4	4.4
Ondansetron Hydrochloride	219	4.4	4.4
Ritonavir 100 Mg	27	4.4	4.4
Tranexamic Acid	16	4.3	4.4
Vancomycin Hydrochloride	117	4.3	4.3
Methylprednisolone	239	4.3	4.3
Metoclopramide	95	4.2	4.2
Atovaquone	14	4.2	4.2
Hydrocortisone Acetate	125	4.2	4.2
Entecavir	20	4.1	4.1
Bisacodyl Suppositories	22	4.1	4.1
Biscodyl	22	4.1	4.1
Amoxicillin And Clavulanate Potassium	45	4.0	4.0
Darunavir	25	4.0	4.0
Sodium Chloride	129	4.0	4.0
Bisacodyl	23	4.0	4.0
Sodium Chloride Tablet	119	3.9	3.9
Sodium Chloride Tablets	119	3.9	3.9
Sucralfate Oral	23	3.9	3.9
Selinexor	14	3.9	3.9
Sucralfate Oral Suspension	23	3.9	3.9
Ursodiol	35	3.9	3.9
Pembrolizumab	164	3.8	3.8
Ixazomib	45	3.8	3.8
Magnesium Hydroxide	21	3.8	3.8
Heparin Sodium	21	3.7	3.7
Prochlorperazine Maleate	14	3.7	3.7
Dalteparin Sodium	16	3.7	3.7
Imatinib Mesylate	42	3.6	3.7
Nivolumab	144	3.6	3.6
Irinotecan Hydrochloride	19	3.6	3.6
Metoclopramide Hydrochloride	113	3.6	3.6
Hydrocortisone	128	3.5	3.5
Prochlorperazine	40	3.5	3.5
Pazopanib Hydrochloride	39	3.5	3.5
Mercaptopurine	25	3.5	3.5
Amphotericin B	18	3.5	3.5
Docetaxel Anhydrous	95	3.4	3.4
Docetaxel	95	3.4	3.4
Trastuzumab	95	3.4	3.4
Levofloxacin	83	3.3	3.3
Levofloxacin In 5% Dextrose	83	3.3	3.3
Potassium Chloride, Dextrose Monohydrate	127	3.3	3.3
Potassium Chloride Oral	127	3.3	3.3
Potassium Chloride Extended-Release	127	3.3	3.3
Oseltamivir	11	3.3	3.3
Durvalumab	28	3.3	3.3
Zoledronic Acid	55	3.3	3.3
Pertuzumab	37	3.3	3.3
Thiotepa	13	3.3	3.3
Bevacizumab	166	3.3	3.3
Cladribine	13	3.3	3.3
Ursosiol	26	3.2	3.2
Enoxaparin Sodium	76	3.2	3.2
Ceftriaxone	43	3.2	3.2
Ceftriaxone Sodium	50	3.2	3.2
Sunitinib Malate	51	3.1	3.1
Amikacin	22	3.1	3.1
Morphine	95	3.1	3.1
Dasatinib	46	3.0	3.0
Tretinoin	10	3.0	3.0
Furosemide	473	3.0	3.0
Panitumumab	19	2.9	2.9
Sucralfate	29	2.9	2.9
Atropine	10	2.9	2.9
Sennosides 8.6 Mg Tablets	25	2.9	2.9
Diphenhydramine	75	2.9	2.9
Senna	25	2.9	2.9
Potassium Chloride	133	2.8	2.8
Sennosides	35	2.8	2.8
Acetylcysteine	11	2.8	2.8
Loperamide Hcl	15	2.8	2.8
Valganciclovir Hydrochloride Powder,	14	2.8	2.8
Anakinra	19	2.8	2.8
Rabeprazole	25	2.7	2.7
Lactulose	43	2.7	2.7
Ciprofolxacin	80	2.7	2.7
Ciprofloxacin Tablets	80	2.7	2.7
Cetuximab	35	2.7	2.7
Ofatumumab	37	2.7	2.7
Standardized Senna Concentrate	14	2.7	2.7
Acetaminophen Tablet Extended Release	276	2.7	2.7
Trimethoprim	13	2.7	2.7
Pain Reliever	276	2.7	2.7
Acetaminophen 500Mg	276	2.7	2.7
Methotrexate	448	2.7	2.7
Fam-Trastuzumab Deruxtecan-Nxki	11	2.6	2.6
Senna Leaf	25	2.6	2.6
Loperamide Hydrochloride Oral	11	2.6	2.6
Ado-Trastuzumab Emtansine	9	2.6	2.6
Lenalidomide	437	2.6	2.6
Telmisartan	19	2.6	2.6
Nilotinib	31	2.5	2.5
Famotidine	122	2.5	2.5
Drs. Clotrimazole	12	2.5	2.5
Family Wellness Clotrimazole	12	2.5	2.5
Pomalidomide	106	2.5	2.5
Clotrimazole Topical	12	2.5	2.5
Methotrexate Sodium	486	2.5	2.5
Torsemide	34	2.5	2.5
Bumetanide	27	2.5	2.5
Valganciclovir	19	2.4	2.4
Valganciclovir Hydrochloride	19	2.4	2.4
Alteplase	15	2.4	2.4
Ritonavir	29	2.4	2.4
Anti-Thymocyte Globulin (Rabbit)	8	2.4	2.4
Diphenhydramine Hcl	11	2.4	2.4
Cefazolin	9	2.4	2.4
Dicyclomine Hydrochloride	14	2.4	2.4
Clotrimazole	12	2.4	2.4
Ciprofloxacin	88	2.3	2.3
Tacrolimus Ointment 0.1%	119	2.3	2.3
Tacrolimus Extended-Release Capsules	119	2.3	2.3
Lopinavir And Ritonavir	13	2.3	2.3
Nifedipine	45	2.3	2.3
Candesartan	34	2.3	2.3
Fentanyl Citrate	17	2.3	2.3
Nebivolol	15	2.3	2.3
Atropine Sulfate	10	2.2	2.2
Ciprofloxacin Hydrochloride	89	2.2	2.2
Esomeprazole	56	2.2	2.2
Melatonin	49	2.2	2.2
Esomeprazole Magnesium Capsule, Delayed Release	13	2.2	2.2
Esomeprazole Magnesium Delayed Release Capsules	13	2.2	2.2
Esomeprazole Magnesium Dihydrate	13	2.2	2.2
Tacrolimus	137	2.1	2.1
Felodipine Extended-Release Tablets	10	2.1	2.1
Felodipine	10	2.1	2.1
Colchicine	23	2.1	2.1
Midazolam	22	2.1	2.1
Diphenhydramine Hydrochloride	143	2.1	2.1
Meperidine Hydrochloride	8	2.1	2.1
Iohexol	7	2.0	2.0
Cefazolin Sodium	10	2.0	2.0
Fentanyl	81	2.0	2.0
Midazolam Hydrochloride	22	2.0	2.0
Clarithromycin	28	2.0	2.0
Tobramycin Sulfate	10	2.0	2.0
Instalax Polyethylene Glycol 3350	10	1.9	1.9
Amiodarone Hydrochloride	9	1.9	1.9
Lorazepam	142	1.9	1.9
Polyethylene Glycol 400	10	1.9	1.9
Bicalutamide	12	1.9	1.9
Bisoprolol Fumarate	106	1.9	1.9
Acetaminophen	341	1.9	1.9
Prednisolone Acetate	8	1.9	1.9
Rabeprazole Sodium	21	1.9	1.9
Dorzolamide Hydrochloride And Timolol Maleate	6	1.8	1.8
Tobramycin Solution	9	1.8	1.8
Vemurafenib	9	1.8	1.8
Linezolid	22	1.8	1.8
Oseltamivir Phosphate	18	1.8	1.8
Insulin	41	1.8	1.8
Mycophenolate Mofetil Hydrochloride	99	1.8	1.8
Gemfibrozil	11	1.8	1.8
Mycophenolate Mofetil	98	1.8	1.8
Amlodipine Besylate And Valsartan	8	1.7	1.7
Axitinib	14	1.7	1.7
Tramadol Hydrochloride	27	1.7	1.7
Propofol	26	1.7	1.7
Dabrafenib	15	1.7	1.7
Busulfan	11	1.7	1.7
Sevelamer Carbonate	8	1.7	1.7
Rifampicin	7	1.7	1.7
Tamsulosin Hydrochloride	14	1.7	1.7
Pitavastatin Calcium	7	1.7	1.7
Tocilizumab	77	1.6	1.6
Loperamide Hydrochloride	30	1.6	1.6
Nebivolol Hydrochloride	22	1.6	1.6
Loratadine Oral	32	1.6	1.6
Darbepoetin Alfa	35	1.6	1.6
Lamivudine Oral	16	1.5	1.5
Erythropoietin	13	1.5	1.5
Amlodipine	166	1.5	1.5
Pegfilgrastim	61	1.5	1.5
Regorafenib	7	1.5	1.5
Sevoflurane	5	1.5	1.5
Ruxolitinib	43	1.5	1.5
Lapatinib	9	1.4	1.4
Tenofovir Disoproxil Fumarate Tablets	5	1.4	1.4
Alpelisib	5	1.4	1.4
Bosutinib	5	1.3	1.3
Cabozantinib	26	1.3	1.3
Oxycodone	98	1.3	1.3
Erlotinib	5	1.2	1.2
Abiraterone	7	1.2	1.2
Pemetrexed Disodium	19	1.2	1.2
Trametinib	12	1.2	1.2
Erlotinib Hydrochloride	6	1.2	1.2
Crizotinib	6	1.1	1.1
Daptomycin	4	1.0	1.0
Morphine Sulfate	48	1.0	1.0
Pemetrexed	8	0.9	0.9
Trifluridine And Tipiracil	4	0.9	0.9
Oxycodone Hydrochloride	75	0.8	0.8
Remdesivir	4	0.7	0.7
Abiraterone Acetate	10	0.6	0.6
Enzalutamide	14	0.6	0.6
Salicylic Acid	5	0.2	0.2

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.