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Drug

Gabapentin Enacarbil

96 flagged reaction(s) · 2,680 total co-reports · max PRR 26.3
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Toxicity To Various Agents 594 26.3 33.0 signal
2 Completed Suicide 277 24.5 27.0 signal
3 Restless Legs Syndrome 56 22.9 23.3 signal
4 Full Blood Count Abnormal 32 22.6 22.8 signal
5 Myoclonus 33 20.6 20.8 signal
6 Cardio-respiratory Arrest 110 19.4 20.2 signal
7 Sleep Disorder Due To A General Medical Condition 34 15.6 15.8 signal
8 Appendicitis 17 13.6 13.6 signal
9 Accidental Overdose 66 13.4 13.7 signal
10 Sputum Discoloured 16 12.6 12.6 signal
11 Drug Abuse 138 12.2 12.8 signal
12 Drug Withdrawal Syndrome Neonatal 21 10.4 10.5 signal
13 Neuralgia 34 10.4 10.5 signal
14 Ventricular Fibrillation 15 10.0 10.0 signal
15 Sensory Disturbance 21 9.7 9.7 signal
16 Impaired Driving Ability 14 9.1 9.2 signal
17 Cardiogenic Shock 15 7.8 7.8 signal
18 Product Odour Abnormal 10 7.1 7.2 signal
19 Hyperlipidaemia 11 6.8 6.8 signal
20 Bacterial Infection 17 6.8 6.8 signal
21 Therapeutic Response Unexpected 38 6.3 6.3 signal
22 Initial Insomnia 8 5.8 5.8 signal
23 Dyskinesia 29 5.3 5.3 signal
24 Incorrect Route Of Product Administration 12 5.3 5.3 signal
25 Bladder Disorder 7 5.2 5.2 signal
26 Ulcer 11 5.1 5.1 signal
27 Sleep Apnoea Syndrome 13 5.0 5.1 signal
28 Therapeutic Response Shortened 21 4.9 4.9 signal
29 Respiratory Depression 8 4.8 4.8 signal
30 Sedation 17 4.8 4.9 signal
31 Dyspnoea Exertional 24 4.7 4.8 signal
32 Seasonal Allergy 9 4.7 4.7 signal
33 Chronic Obstructive Pulmonary Disease 33 4.7 4.7 signal
34 Somnolence 125 4.6 4.8 signal
35 Gout 11 4.5 4.6 signal
36 Drug Ineffective For Unapproved Indication 34 4.5 4.6 signal
37 Poor Quality Product Administered 6 4.4 4.4 signal
38 Spinal Operation 7 4.3 4.3 signal
39 Hereditary Angioedema 6 4.2 4.2 signal
40 Muscle Spasticity 7 4.2 4.2 signal
41 Wheezing 32 4.0 4.0 signal
42 Multiple Organ Dysfunction Syndrome 15 4.0 4.0 signal
43 Therapeutic Product Effect Incomplete 38 4.0 4.0 signal
44 Affect Lability 5 3.8 3.8 signal
45 Inability To Afford Medication 5 3.8 3.8 signal
46 Intentional Product Misuse 44 3.8 3.8 signal
47 Middle Insomnia 9 3.6 3.6 signal
48 Abnormal Dreams 13 3.5 3.5 signal
49 Bedridden 6 3.4 3.4 signal
50 Activities Of Daily Living Impaired 9 3.3 3.3 signal
51 Drug Effective For Unapproved Indication 13 3.3 3.3 signal
52 Limb Injury 12 3.3 3.3 signal
53 Product Prescribing Issue 9 3.3 3.3 signal
54 Disturbance In Attention 23 3.2 3.2 signal
55 Pharyngeal Swelling 4 3.1 3.1 no signal
56 Asthma 46 3.0 3.1 signal
57 Nightmare 14 3.0 3.0 signal
58 Withdrawal Syndrome 17 3.0 3.0 signal
59 Feeling Abnormal 95 2.9 3.0 signal
60 Mental Impairment 9 2.7 2.8 signal
61 Feeling Jittery 7 2.7 2.7 signal
62 Product Packaging Quantity Issue 4 2.7 2.7 no signal
63 Mania 6 2.7 2.7 signal
64 Medication Error 20 2.7 2.7 signal
65 Prescribed Underdose 7 2.6 2.6 signal
66 Intentional Drug Misuse 7 2.4 2.4 signal
67 Schizophrenia 4 2.4 2.4 no signal
68 Product Dispensing Error 7 2.4 2.4 signal
69 Fracture 6 2.3 2.4 no signal
70 Irritability 19 2.3 2.3 signal
71 Serotonin Syndrome 6 2.3 2.3 no signal
72 Dystonia 6 2.3 2.3 no signal
73 Suicidal Ideation 28 2.3 2.3 signal
74 Product Physical Issue 6 2.2 2.2 no signal
75 Knee Arthroplasty 6 2.1 2.1 no signal
76 Blood Glucose Fluctuation 3 2.0 2.0 no signal
77 Multiple Sclerosis 13 2.0 2.0 signal
78 Colon Cancer 4 2.0 2.0 no signal
79 Blood Count Abnormal 4 1.9 1.9 no signal
80 Injection Site Discolouration 3 1.8 1.8 no signal
81 Multiple Sclerosis Relapse 16 1.7 1.7 no signal
82 Drug Administration Error 7 1.7 1.7 no signal
83 Product Taste Abnormal 3 1.7 1.7 no signal
84 Akathisia 3 1.6 1.6 no signal
85 Extra Dose Administered 8 1.5 1.5 no signal
86 Drug Dispensing Error 3 1.4 1.4 no signal
87 Wrong Technique In Product Usage Process 35 1.3 1.3 no signal
88 Suicide Attempt 10 1.2 1.2 no signal
89 Wrong Technique In Drug Usage Process 6 1.2 1.2 no signal
90 Product Storage Error 13 1.1 1.1 no signal
91 Intentional Self-injury 3 1.1 1.1 no signal
92 Injection Site Bruising 9 0.8 0.8 no signal
93 Product Adhesion Issue 4 0.8 0.8 no signal
94 Intentional Overdose 7 0.8 0.8 no signal
95 Drug Withdrawal Syndrome 8 0.7 0.7 no signal
96 Bladder Cancer 4 0.5 0.5 no signal