OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Isoniazid

1,128 flagged reaction(s) · 61,806 total co-reports · max PRR 1,515.7
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Tuberculoma Of Central Nervous System 98 1,515.7 1,525.0 signal
2 Serpiginous Choroiditis 24 1,283.7 1,285.6 signal
3 Immune Reconstitution Inflammatory Syndrome Associated Tuberculosis 162 1,245.3 1,257.9 signal
4 Vaginal Flatulence 89 536.4 539.4 signal
5 Tuberculosis Of Eye 18 453.1 453.6 signal
6 Tuberculosis Of Central Nervous System 55 339.4 340.6 signal
7 Interferon Gamma Release Assay Positive 34 338.3 339.1 signal
8 Pyelonephritis Fungal 12 256.7 256.9 signal
9 Meningitis Tuberculous 92 254.5 256.0 signal
10 Diaphragmatic Injury 12 252.5 252.7 signal
11 Paradoxical Drug Reaction 554 231.7 239.9 signal
12 Demodicidosis 13 214.0 214.1 signal
13 Haemodilution 13 196.3 196.5 signal
14 Tuberculosis Of Genitourinary System 11 190.8 191.0 signal
15 Nicotinic Acid Deficiency 14 185.3 185.4 signal
16 Hemianopia Heteronymous 10 180.8 180.9 signal
17 Tuberculosis Skin Test Positive 10 178.3 178.4 signal
18 Pericarditis Tuberculous 11 158.7 158.8 signal
19 Tuberculosis Gastrointestinal 34 156.4 156.8 signal
20 Sideroblastic Anaemia 14 142.6 142.8 signal
21 Splenic Embolism 11 141.2 141.3 signal
22 Acid Fast Bacilli Infection 15 136.6 136.7 signal
23 Peritoneal Tuberculosis 39 128.0 128.4 signal
24 Immune Reconstitution Syndrome 116 126.7 127.6 signal
25 Choroiditis 33 125.3 125.6 signal
26 Intestinal Tuberculosis 15 121.1 121.2 signal
27 Extrapulmonary Tuberculosis 25 119.7 119.9 signal
28 Disseminated Tuberculosis 207 115.2 116.7 signal
29 Lymph Node Tuberculosis 60 114.3 114.7 signal
30 Disseminated Bacillus Calmette-guerin Infection 36 108.5 108.7 signal
31 Cutaneous Tuberculosis 14 107.0 107.1 signal
32 Bone Tuberculosis 28 102.7 102.9 signal
33 Tuberculous Pleurisy 34 100.1 100.3 signal
34 Thalassaemia 12 97.5 97.6 signal
35 Mycobacterium Kansasii Infection 11 92.3 92.4 signal
36 Pulmonary Tuberculosis 282 92.2 93.8 signal
37 Hepatic Haematoma 31 90.2 90.4 signal
38 Gingivitis Ulcerative 13 85.1 85.2 signal
39 Congestive Hepatopathy 26 80.8 80.9 signal
40 Immune Reconstitution Inflammatory Syndrome 283 78.0 79.4 signal
41 Bovine Tuberculosis 21 75.1 75.2 signal
42 Mycobacterium Fortuitum Infection 10 74.2 74.2 signal
43 Female Genital Tract Fistula 92 73.5 73.9 signal
44 Hepatitis B Core Antibody Positive 20 73.1 73.2 signal
45 Pancreatitis Haemorrhagic 23 67.4 67.5 signal
46 Disseminated Mycobacterium Avium Complex Infection 10 64.2 64.2 signal
47 Toxic Optic Neuropathy 20 63.4 63.5 signal
48 Infective Aneurysm 22 61.4 61.5 signal
49 Vitamin B1 Decreased 11 59.8 59.9 signal
50 Tuberculosis 547 57.8 59.8 signal
51 Oedematous Kidney 11 56.3 56.3 signal
52 Latent Tuberculosis 82 53.2 53.5 signal
53 Urinary Tract Inflammation 14 53.0 53.1 signal
54 Dandy-walker Syndrome 10 52.0 52.0 signal
55 Cerebellar Ataxia 36 50.6 50.7 signal
56 Herpes Zoster Meningoencephalitis 13 48.7 48.7 signal
57 Papilloma 11 46.6 46.6 signal
58 Radiculopathy 91 46.5 46.8 signal
59 Granulomatous Liver Disease 24 45.9 46.0 signal
60 Hepatitis Toxic 86 44.1 44.3 signal
61 Thalamic Infarction 19 43.0 43.1 signal
62 Mycobacterial Infection 55 42.9 43.1 signal
63 Proctitis 88 42.2 42.4 signal
64 Conductive Deafness 10 41.5 41.6 signal
65 Loss Of Employment 91 40.0 40.3 signal
66 Splenic Abscess 12 40.0 40.0 signal
67 Tuberculin Test Positive 76 39.7 39.9 signal
68 Renal Transplant Failure 29 39.3 39.4 signal
69 Drug Reaction With Eosinophilia And Systemic Symptoms 744 39.0 40.9 signal
70 Accelerated Hypertension 11 38.9 38.9 signal
71 Drug-induced Liver Injury 862 37.4 39.5 signal
72 Oedematous Pancreatitis 15 35.9 36.0 signal
73 Central Nervous System Vasculitis 13 35.6 35.6 signal
74 Jarisch-herxheimer Reaction 19 35.6 35.6 signal
75 Chronic Sinusitis 97 34.6 34.8 signal
76 Disseminated Mucormycosis 10 34.4 34.4 signal
77 Mycobacterium Abscessus Infection 18 34.1 34.1 signal
78 Mycobacterium Tuberculosis Complex Test Positive 60 33.8 34.0 signal
79 Antipsychotic Drug Level Decreased 13 32.6 32.6 signal
80 Multiple-drug Resistance 75 32.3 32.5 signal
81 Kaposi's Sarcoma 12 31.4 31.4 signal
82 Hypermetabolism 12 30.4 30.4 signal
83 Immunosuppressant Drug Level Decreased 27 30.2 30.2 signal
84 Hepatotoxicity 499 30.0 30.9 signal
85 Optic Neuropathy 47 29.8 29.9 signal
86 Vasculitis Cerebral 10 29.1 29.1 signal
87 Marrow Hyperplasia 15 29.0 29.0 signal
88 Type Iii Immune Complex Mediated Reaction 12 28.7 28.7 signal
89 Coma Hepatic 16 28.4 28.4 signal
90 Delayed Graft Function 15 28.2 28.2 signal
91 Acute Hepatic Failure 285 27.9 28.3 signal
92 Granuloma 69 26.5 26.6 signal
93 Strongyloidiasis 32 26.2 26.2 signal
94 Glomerulonephritis Minimal Lesion 14 25.6 25.6 signal
95 Lymphocyte Stimulation Test Positive 15 24.5 24.5 signal
96 Focal Dyscognitive Seizures 21 24.4 24.4 signal
97 Pulmonary Granuloma 21 24.2 24.2 signal
98 Complications Of Transplanted Kidney 40 23.8 23.8 signal
99 Drug Resistance 458 23.6 24.3 signal
100 Psoas Abscess 11 23.5 23.5 signal
101 Pneumocystis Jiroveci Pneumonia 39 22.9 22.9 signal
102 Microcytic Anaemia 36 22.8 22.8 signal
103 Optic Atrophy 28 22.6 22.6 signal
104 Hepatitis Fulminant 50 22.3 22.3 signal
105 Liver Transplant Rejection 30 21.9 22.0 signal
106 Hepatic Encephalopathy 153 21.7 21.9 signal
107 Ocular Toxicity 17 21.2 21.3 signal
108 Hilar Lymphadenopathy 14 21.2 21.2 signal
109 Cerebral Toxoplasmosis 15 21.2 21.2 signal
110 Erythrodermic Psoriasis 13 21.0 21.0 signal
111 Arachnoiditis 11 21.0 21.0 signal
112 Unmasking Of Previously Unidentified Disease 17 20.9 20.9 signal
113 Chorioretinitis 10 20.5 20.6 signal
114 Pneumonia Cryptococcal 14 19.8 19.8 signal
115 Cholestatic Liver Injury 32 19.7 19.8 signal
116 Hydrocephalus 81 19.7 19.8 signal
117 Enterovesical Fistula 11 19.2 19.3 signal
118 Anaemia Of Chronic Disease 13 19.0 19.0 signal
119 Jaundice 386 18.9 19.3 signal
120 Hepatitis 363 18.7 19.1 signal
121 Colour Blindness 13 18.6 18.6 signal
122 Adrenocortical Insufficiency Acute 27 18.6 18.6 signal
123 Chronic Allograft Nephropathy 11 18.4 18.4 signal
124 Acinetobacter Infection 15 18.3 18.3 signal
125 Hyperuricaemia 56 18.0 18.1 signal
126 Bilirubin Conjugated Increased 31 17.6 17.6 signal
127 Hepatosplenomegaly 34 17.4 17.4 signal
128 Hepatic Necrosis 49 17.1 17.1 signal
129 Lymphadenitis 31 16.9 16.9 signal
130 Cryptococcosis 20 16.4 16.4 signal
131 Antipsychotic Drug Level Above Therapeutic 11 16.1 16.1 signal
132 Lichenoid Keratosis 27 15.7 15.8 signal
133 Ototoxicity 22 15.6 15.6 signal
134 Abdominal Lymphadenopathy 10 15.3 15.3 signal
135 Oral Candidiasis 150 15.2 15.3 signal
136 Atypical Mycobacterial Infection 16 15.1 15.1 signal
137 Drug Level Decreased 116 14.9 15.0 signal
138 Hepatitis Cholestatic 68 14.9 15.0 signal
139 Substance-induced Psychotic Disorder 25 14.9 14.9 signal
140 Cerebral Ventricle Dilatation 13 14.8 14.8 signal
141 Renal Atrophy 14 14.7 14.7 signal
142 Neuropsychiatric Symptoms 10 14.3 14.4 signal
143 Distributive Shock 24 14.3 14.3 signal
144 Liver Transplant 39 14.2 14.2 signal
145 Hypertransaminasaemia 73 14.1 14.1 signal
146 Encephalitis 73 13.9 14.0 signal
147 Lymphadenopathy Mediastinal 20 13.8 13.8 signal
148 Meningitis Cryptococcal 18 13.7 13.7 signal
149 Drug Rash With Eosinophilia And Systemic Symptoms 34 13.6 13.6 signal
150 Mycobacterium Avium Complex Infection 27 13.3 13.4 signal
151 Blood Bicarbonate Decreased 19 13.1 13.1 signal
152 Hepatic Cyst 33 12.8 12.8 signal
153 Hepatic Steatosis 178 12.6 12.7 signal
154 Trisomy 21 12 12.4 12.4 signal
155 Vaginal Discharge 95 12.4 12.5 signal
156 Systemic Mycosis 11 12.4 12.4 signal
157 Respiratory Alkalosis 15 12.2 12.2 signal
158 Labelled Drug-drug Interaction Issue 13 12.2 12.2 signal
159 Pathogen Resistance 84 12.1 12.2 signal
160 Henoch-schonlein Purpura 20 12.1 12.1 signal
161 Aplasia Pure Red Cell 31 11.8 11.8 signal
162 Cachexia 46 11.8 11.8 signal
163 Blood Hiv Rna Increased 16 11.7 11.7 signal
164 Transaminases Increased 195 11.5 11.6 signal
165 Infectious Pleural Effusion 13 11.3 11.3 signal
166 Transplant Dysfunction 15 11.2 11.2 signal
167 Incision Site Pain 10 11.2 11.2 signal
168 Pseudomembranous Colitis 19 11.1 11.1 signal
169 Optic Neuritis 77 11.1 11.1 signal
170 Eosinophilia 147 11.0 11.1 signal
171 Cd4 Lymphocytes Decreased 18 10.9 10.9 signal
172 Cytomegalovirus Chorioretinitis 16 10.9 10.9 signal
173 Osteolysis 17 10.9 10.9 signal
174 Nocardiosis 21 10.7 10.8 signal
175 Splenic Infarction 14 10.6 10.6 signal
176 Escherichia Urinary Tract Infection 34 10.5 10.5 signal
177 Rash Morbilliform 22 10.4 10.4 signal
178 Lung Consolidation 22 10.3 10.3 signal
179 Nephritis Interstitial 10 10.2 10.2 signal
180 Haemophagocytic Lymphohistiocytosis 56 10.2 10.2 signal
181 Ocular Icterus 33 10.0 10.0 signal
182 Oesophageal Candidiasis 30 9.9 10.0 signal
183 Hepatic Failure 229 9.9 10.1 signal
184 Encephalopathy 185 9.9 10.0 signal
185 Hypersensitivity Vasculitis 20 9.9 9.9 signal
186 Vascular Pseudoaneurysm 13 9.8 9.8 signal
187 Liver Injury 177 9.6 9.7 signal
188 Hepatitis Acute 47 9.5 9.5 signal
189 Aspergillus Infection 47 9.5 9.5 signal
190 Anticoagulation Drug Level Above Therapeutic 11 9.3 9.3 signal
191 Transplant Rejection 57 9.3 9.4 signal
192 Gaze Palsy 12 9.2 9.2 signal
193 Hiv Infection 21 9.1 9.1 signal
194 Bile Duct Obstruction 13 8.8 8.9 signal
195 Paraesthesia Oral 96 8.7 8.8 signal
196 Electrocardiogram St Segment Elevation 22 8.7 8.7 signal
197 Hepatomegaly 65 8.6 8.7 signal
198 Chest X-ray Abnormal 20 8.4 8.5 signal
199 Lymphadenopathy 227 8.4 8.5 signal
200 Fungaemia 10 8.4 8.4 signal
201 Macular Degeneration 76 8.3 8.4 signal
202 Dermatitis Exfoliative 32 8.3 8.3 signal
203 Histiocytosis Haematophagic 19 8.3 8.3 signal
204 Disseminated Intravascular Coagulation 89 8.3 8.3 signal
205 Focal Segmental Glomerulosclerosis 10 8.2 8.2 signal
206 Pneumonia Cytomegaloviral 12 8.2 8.2 signal
207 Type Iv Hypersensitivity Reaction 17 8.2 8.2 signal
208 Rash Maculo-papular 138 8.2 8.2 signal
209 Blood Pressure Diastolic Abnormal 16 8.1 8.2 signal
210 Mucormycosis 16 8.1 8.1 signal
211 Autoimmune Haemolytic Anaemia 21 8.1 8.1 signal
212 Immune System Disorder 81 8.1 8.1 signal
213 Computerised Tomogram Abnormal 14 8.0 8.0 signal
214 Prothrombin Time Prolonged 37 8.0 8.0 signal
215 Hyperbilirubinaemia 63 8.0 8.0 signal
216 Leukocytoclastic Vasculitis 10 7.9 7.9 signal
217 Type I Hypersensitivity 21 7.9 7.9 signal
218 Meningitis 40 7.8 7.9 signal
219 Vaccination Failure 10 7.8 7.8 signal
220 Liver Function Test Abnormal 175 7.8 7.9 signal
221 Drug Interaction 935 7.7 8.1 signal
222 Pleurisy 35 7.7 7.7 signal
223 Hepatic Function Abnormal 214 7.6 7.6 signal
224 Necrosis 32 7.5 7.5 signal
225 Myocarditis 64 7.4 7.4 signal
226 Toxic Epidermal Necrolysis 84 7.3 7.3 signal
227 Dermatitis Exfoliative Generalised 19 7.2 7.2 signal
228 Alanine Aminotransferase Increased 337 7.2 7.3 signal
229 Hepatic Cytolysis 67 7.2 7.2 signal
230 Aspartate Aminotransferase Increased 288 7.1 7.2 signal
231 Coagulopathy 90 7.1 7.1 signal
232 Liver Disorder 239 7.1 7.1 signal
233 Opportunistic Infection 10 7.1 7.1 signal
234 Drug Eruption 95 7.0 7.1 signal
235 Renal Tubular Necrosis 51 6.8 6.8 signal
236 Hyporeflexia 10 6.8 6.8 signal
237 Lung Infiltration 46 6.8 6.8 signal
238 Mixed Liver Injury 15 6.7 6.7 signal
239 Pseudomonas Infection 43 6.6 6.7 signal
240 Face Oedema 86 6.6 6.7 signal
241 Blood Bilirubin Increased 137 6.6 6.7 signal
242 Macule 14 6.6 6.6 signal
243 Cell Death 10 6.6 6.6 signal
244 Intracranial Pressure Increased 28 6.6 6.6 signal
245 Cytomegalovirus Viraemia 22 6.6 6.6 signal
246 Crepitations 15 6.5 6.5 signal
247 Tubulointerstitial Nephritis 93 6.5 6.5 signal
248 Splenomegaly 58 6.5 6.5 signal
249 Stillbirth 24 6.5 6.5 signal
250 Drug Level Below Therapeutic 27 6.4 6.4 signal
251 Adenovirus Infection 14 6.4 6.4 signal
252 Implant Site Infection 11 6.4 6.4 signal
253 Areflexia 13 6.3 6.3 signal
254 Hepatocellular Injury 68 6.3 6.3 signal
255 Klebsiella Infection 24 6.2 6.3 signal
256 Renal Cyst 38 6.2 6.3 signal
257 Oculogyric Crisis 10 6.2 6.2 signal
258 Brain Abscess 12 6.2 6.2 signal
259 Immune Thrombocytopenia 21 6.1 6.1 signal
260 Blood Uric Acid Increased 27 6.1 6.1 signal
261 Pancreatitis Chronic 11 6.1 6.1 signal
262 Neurotoxicity 81 6.1 6.1 signal
263 Toxic Encephalopathy 23 6.1 6.1 signal
264 Low Birth Weight Baby 37 6.1 6.1 signal
265 Acute Generalised Exanthematous Pustulosis 36 6.1 6.1 signal
266 Abdominal Tenderness 23 6.1 6.1 signal
267 Liver Abscess 15 6.0 6.1 signal
268 Antinuclear Antibody Positive 15 6.0 6.0 signal
269 Generalised Tonic-clonic Seizure 75 6.0 6.0 signal
270 Deafness Neurosensory 15 6.0 6.0 signal
271 Hyperreflexia 16 6.0 6.0 signal
272 Pericardial Effusion 105 6.0 6.0 signal
273 Vasculitis 53 5.9 6.0 signal
274 Polyneuropathy 54 5.9 5.9 signal
275 Bronchopulmonary Aspergillosis 35 5.9 5.9 signal
276 Glomerulonephritis 11 5.9 5.9 signal
277 Bacterial Test Positive 10 5.9 5.9 signal
278 Labelled Drug-drug Interaction Medication Error 40 5.9 5.9 signal
279 Iridocyclitis 14 5.9 5.9 signal
280 Systemic Inflammatory Response Syndrome 17 5.8 5.8 signal
281 Acute Psychosis 11 5.8 5.8 signal
282 Lupus-like Syndrome 40 5.8 5.8 signal
283 Nephrotic Syndrome 30 5.7 5.7 signal
284 Stupor 14 5.7 5.7 signal
285 Dyslipidaemia 22 5.7 5.7 signal
286 Multiple Organ Dysfunction Syndrome 119 5.6 5.6 signal
287 Purulent Discharge 18 5.5 5.5 signal
288 Subcutaneous Abscess 20 5.4 5.4 signal
289 Hepatic Enzyme Increased 282 5.4 5.5 signal
290 Kidney Transplant Rejection 20 5.4 5.4 signal
291 Cytomegalovirus Infection 69 5.4 5.4 signal
292 Enterococcal Infection 20 5.4 5.4 signal
293 Stevens-johnson Syndrome 92 5.4 5.4 signal
294 Acute Respiratory Distress Syndrome 73 5.4 5.4 signal
295 Pancreatitis Acute 92 5.4 5.4 signal
296 Lymphopenia 58 5.4 5.4 signal
297 Brain Oedema 52 5.4 5.4 signal
298 Pulmonary Mass 61 5.4 5.4 signal
299 Pneumocystis Jirovecii Pneumonia 41 5.4 5.4 signal
300 Cardiopulmonary Failure 16 5.3 5.3 signal
301 Hallucinations, Mixed 17 5.3 5.3 signal
302 Haemolytic Anaemia 36 5.2 5.2 signal
303 Serum Ferritin Increased 21 5.2 5.2 signal
304 Hypovolaemic Shock 19 5.2 5.2 signal
305 Papilloedema 18 5.2 5.2 signal
306 Hepatitis B 24 5.2 5.2 signal
307 Pancytopenia 220 5.2 5.2 signal
308 Blood Albumin Decreased 31 5.1 5.1 signal
309 Virologic Failure 21 5.1 5.1 signal
310 Papule 27 5.1 5.1 signal
311 Oligohydramnios 13 5.1 5.1 signal
312 Oliguria 24 5.0 5.1 signal
313 C-reactive Protein Increased 140 5.0 5.1 signal
314 Wound Dehiscence 13 5.0 5.0 signal
315 Pneumonia Bacterial 35 5.0 5.0 signal
316 Maternal Exposure During Breast Feeding 15 5.0 5.0 signal
317 Immunosuppression 33 5.0 5.0 signal
318 Nystagmus 20 4.9 4.9 signal
319 Metabolic Acidosis 119 4.9 4.9 signal
320 Activated Partial Thromboplastin Time Prolonged 19 4.9 4.9 signal
321 Purpura 33 4.9 4.9 signal
322 Brain Herniation 11 4.8 4.8 signal
323 Thrombotic Thrombocytopenic Purpura 13 4.8 4.8 signal
324 Normochromic Normocytic Anaemia 11 4.8 4.8 signal
325 Contraindicated Product Administered 110 4.8 4.8 signal
326 Blood Alkaline Phosphatase Increased 90 4.7 4.7 signal
327 Procedural Pain 100 4.7 4.7 signal
328 Serotonin Syndrome 69 4.7 4.7 signal
329 Frequent Bowel Movements 97 4.7 4.7 signal
330 Ascites 106 4.7 4.7 signal
331 Pleural Effusion 217 4.7 4.7 signal
332 Erythema Multiforme 33 4.6 4.6 signal
333 Coma Scale Abnormal 10 4.6 4.6 signal
334 Bacteraemia 41 4.5 4.6 signal
335 Foetal Growth Restriction 21 4.5 4.5 signal
336 Gamma-glutamyltransferase Increased 77 4.5 4.5 signal
337 Haemodynamic Instability 26 4.5 4.5 signal
338 Shock 79 4.5 4.5 signal
339 Status Epilepticus 39 4.5 4.5 signal
340 Exposure During Pregnancy 213 4.5 4.5 signal
341 Grand Mal Convulsion 32 4.5 4.5 signal
342 Haemodialysis 29 4.5 4.5 signal
343 Cholestasis 65 4.4 4.5 signal
344 Leukocytosis 61 4.4 4.4 signal
345 Gastrointestinal Perforation 14 4.4 4.4 signal
346 Abdominal Mass 9 4.4 4.4 signal
347 Conjunctival Hyperaemia 12 4.4 4.4 signal
348 Cutaneous Vasculitis 12 4.4 4.4 signal
349 Clostridium Difficile Colitis 35 4.3 4.3 signal
350 Gastroenteritis 48 4.3 4.3 signal
351 Inflammatory Marker Increased 16 4.3 4.3 signal
352 Lung Neoplasm 14 4.2 4.3 signal
353 Psychiatric Symptom 24 4.2 4.2 signal
354 Inappropriate Antidiuretic Hormone Secretion 33 4.2 4.2 signal
355 Herpes Simplex 21 4.2 4.2 signal
356 Pyrexia 1,102 4.2 4.4 signal
357 Skin Lesion 86 4.1 4.1 signal
358 Red Blood Cell Sedimentation Rate Increased 35 4.1 4.1 signal
359 Demyelination 13 4.1 4.1 signal
360 Enterocolitis 18 4.1 4.1 signal
361 Nephropathy Toxic 35 4.1 4.1 signal
362 Eosinophil Count Increased 26 4.1 4.1 signal
363 Colitis Ulcerative 139 4.1 4.1 signal
364 Ataxia 37 4.1 4.1 signal
365 Bacterial Sepsis 10 4.0 4.0 signal
366 Malnutrition 34 4.0 4.0 signal
367 Organising Pneumonia 15 4.0 4.0 signal
368 Polyuria 25 4.0 4.0 signal
369 Blood Urea Increased 51 4.0 4.0 signal
370 Acute Respiratory Failure 58 4.0 4.0 signal
371 Pneumothorax 48 4.0 4.0 signal
372 Skin Mass 20 3.9 3.9 signal
373 Generalised Oedema 37 3.9 3.9 signal
374 Azotaemia 12 3.9 3.9 signal
375 Pulmonary Toxicity 21 3.9 3.9 signal
376 Atelectasis 29 3.9 3.9 signal
377 Cytolytic Hepatitis 10 3.9 3.9 signal
378 Ammonia Increased 15 3.8 3.8 signal
379 Hepatic Fibrosis 10 3.8 3.8 signal
380 Colitis 110 3.8 3.8 signal
381 Pustular Psoriasis 10 3.8 3.8 signal
382 Uveitis 39 3.8 3.8 signal
383 Finger Deformity 14 3.8 3.8 signal
384 Petechiae 30 3.8 3.8 signal
385 Pulseless Electrical Activity 12 3.8 3.8 signal
386 Hemiparesis 49 3.7 3.8 signal
387 Rash Pustular 21 3.7 3.7 signal
388 Proteinuria 54 3.7 3.7 signal
389 Liver Function Test Increased 61 3.7 3.7 signal
390 Multi-organ Failure 50 3.7 3.7 signal
391 International Normalised Ratio Increased 82 3.7 3.7 signal
392 Interstitial Lung Disease 137 3.7 3.7 signal
393 Pneumonia Fungal 11 3.7 3.7 signal
394 Hepatic Enzyme Abnormal 14 3.7 3.7 signal
395 Tachypnoea 38 3.7 3.7 signal
396 Septic Shock 121 3.7 3.7 signal
397 Polydipsia 11 3.6 3.6 signal
398 Therapeutic Product Effect Decreased 123 3.6 3.6 signal
399 Mouth Ulceration 58 3.6 3.6 signal
400 Hemiplegia 23 3.6 3.6 signal
401 Rales 16 3.6 3.6 signal
402 Skin Papilloma 11 3.6 3.6 signal
403 Sarcoidosis 13 3.6 3.6 signal
404 Drug Level Increased 45 3.5 3.6 signal
405 Psychotic Disorder 80 3.5 3.5 signal
406 Treatment Noncompliance 147 3.5 3.6 signal
407 Blood Lactate Dehydrogenase Increased 43 3.5 3.5 signal
408 Viral Mutation Identified 10 3.5 3.5 signal
409 Pulmonary Fibrosis 51 3.5 3.5 signal
410 Respiratory Failure 193 3.4 3.5 signal
411 Rectal Haemorrhage 114 3.4 3.5 signal
412 Breath Sounds Abnormal 13 3.4 3.4 signal
413 Chromaturia 59 3.4 3.4 signal
414 Central Nervous System Lesion 36 3.4 3.4 signal
415 Anorexia 34 3.4 3.4 signal
416 Herpes Virus Infection 15 3.4 3.4 signal
417 Respiratory Rate Increased 23 3.4 3.4 signal
418 Toxic Skin Eruption 26 3.4 3.4 signal
419 Skin Hyperpigmentation 22 3.3 3.4 signal
420 Myopathy 22 3.3 3.3 signal
421 Cerebral Infarction 62 3.3 3.3 signal
422 Anaemia 482 3.3 3.4 signal
423 Lactic Acidosis 81 3.3 3.3 signal
424 Thrombocytopenia 280 3.3 3.3 signal
425 Tonsillitis 13 3.3 3.3 signal
426 Hypoalbuminaemia 19 3.2 3.2 signal
427 Acidosis 19 3.2 3.2 signal
428 Altered State Of Consciousness 53 3.2 3.2 signal
429 Autoimmune Hepatitis 17 3.2 3.2 signal
430 Arthritis Bacterial 10 3.2 3.2 signal
431 Pyelonephritis 21 3.2 3.2 signal
432 Mucous Stools 12 3.2 3.2 signal
433 Haematochezia 134 3.2 3.2 signal
434 Pemphigoid 18 3.2 3.2 signal
435 Hypertensive Crisis 27 3.2 3.2 signal
436 Leukopenia 120 3.1 3.2 signal
437 Neuropathy Peripheral 227 3.1 3.2 signal
438 Hypovolaemia 14 3.1 3.1 signal
439 Drug Toxicity 33 3.1 3.1 signal
440 Premature Delivery 38 3.1 3.1 signal
441 Yellow Skin 11 3.1 3.1 signal
442 Abscess Limb 10 3.1 3.1 signal
443 Hepatic Lesion 10 3.0 3.0 signal
444 Cardiac Tamponade 11 3.0 3.0 signal
445 Skin Necrosis 12 3.0 3.0 signal
446 Cholecystitis Acute 13 3.0 3.0 signal
447 Rebound Effect 26 3.0 3.0 signal
448 Blood Pressure Diastolic Decreased 17 3.0 3.0 signal
449 Neutrophilia 13 3.0 3.0 signal
450 Haemoptysis 64 3.0 3.0 signal
451 Aplastic Anaemia 12 3.0 3.0 signal
452 Infusion Related Reaction 151 3.0 3.0 signal
453 Premature Labour 13 3.0 3.0 signal
454 Cardiac Failure 183 3.0 3.0 signal
455 Skin Disorder 75 2.9 2.9 signal
456 Blood Creatine Increased 10 2.9 2.9 signal
457 Dermatitis Allergic 28 2.9 2.9 signal
458 Anal Abscess 12 2.9 2.9 signal
459 Peripheral Sensory Neuropathy 13 2.9 2.9 signal
460 Pneumonitis 60 2.9 2.9 signal
461 Fistula 25 2.9 2.9 signal
462 Blood Pressure Systolic Decreased 10 2.9 2.9 signal
463 Gastrointestinal Disorder 195 2.9 2.9 signal
464 Escherichia Infection 18 2.9 2.9 signal
465 Abdominal Hernia 10 2.9 2.9 signal
466 Endocarditis 11 2.8 2.8 signal
467 Tendon Disorder 14 2.8 2.8 signal
468 Drug Intolerance 206 2.8 2.8 signal
469 Acute Pulmonary Oedema 12 2.8 2.8 signal
470 Partial Seizures 11 2.8 2.8 signal
471 Gastric Disorder 74 2.8 2.8 signal
472 Neurological Symptom 12 2.8 2.8 signal
473 Hypercalcaemia 26 2.7 2.8 signal
474 Concomitant Disease Aggravated 13 2.7 2.7 signal
475 Respiratory Distress 58 2.7 2.7 signal
476 Blood Lactic Acid Increased 11 2.7 2.7 signal
477 Premature Baby 63 2.7 2.7 signal
478 Blood Pressure Fluctuation 50 2.7 2.7 signal
479 Haemolysis 16 2.7 2.7 signal
480 Electrocardiogram Qt Prolonged 74 2.7 2.7 signal
481 Sinus Tachycardia 29 2.7 2.7 signal
482 Pharyngolaryngeal Pain 11 2.7 2.7 signal
483 Cardiac Failure Congestive 164 2.6 2.7 signal
484 Skin Plaque 17 2.6 2.6 signal
485 Small For Dates Baby 10 2.6 2.6 signal
486 Rhabdomyolysis 83 2.6 2.6 signal
487 Pulmonary Alveolar Haemorrhage 11 2.6 2.6 signal
488 Pigmentation Disorder 12 2.5 2.5 signal
489 Sepsis 217 2.5 2.6 signal
490 Mental Status Changes 54 2.5 2.5 signal
491 Toxicity To Various Agents 324 2.5 2.5 signal
492 Renal Failure Acute 83 2.5 2.5 signal
493 Epstein-barr Virus Infection 12 2.5 2.5 signal
494 Failure To Thrive 10 2.5 2.5 signal
495 Ankylosing Spondylitis 25 2.5 2.5 signal
496 Pulmonary Haemorrhage 15 2.5 2.5 signal
497 Haematocrit Decreased 38 2.5 2.5 signal
498 Staphylococcal Infection 63 2.5 2.5 signal
499 Posterior Reversible Encephalopathy Syndrome 18 2.5 2.5 signal
500 Candida Infection 31 2.4 2.4 signal
501 Therapeutic Product Effect Incomplete 131 2.4 2.4 signal
502 Drug Specific Antibody Present 12 2.4 2.4 signal
503 Lipase Increased 14 2.4 2.4 signal
504 Blood Creatinine Increased 120 2.4 2.4 signal
505 Appendicitis 17 2.4 2.4 signal
506 Renal Impairment 152 2.4 2.4 signal
507 Hyperkalaemia 63 2.4 2.4 signal
508 Treatment Failure 148 2.3 2.4 signal
509 Fungal Infection 60 2.3 2.4 signal
510 Pancreatitis 95 2.3 2.3 signal
511 Rash Erythematous 84 2.3 2.3 signal
512 Blood Pressure Systolic Increased 35 2.3 2.3 signal
513 Cholangitis 11 2.3 2.3 signal
514 Gout 32 2.3 2.3 signal
515 Immune Effector Cell-associated Neurotoxicity Syndrome 10 2.3 2.3 signal
516 Emphysema 18 2.3 2.3 signal
517 Bone Marrow Failure 36 2.3 2.3 signal
518 Pericarditis 29 2.3 2.3 signal
519 Anuria 15 2.3 2.3 signal
520 Generalised Erythema 10 2.3 2.3 signal
521 Ventricular Extrasystoles 18 2.3 2.3 signal
522 Upper Gastrointestinal Haemorrhage 29 2.2 2.2 signal
523 Nephropathy 16 2.2 2.2 signal
524 Immunodeficiency 25 2.2 2.2 signal
525 Intestinal Perforation 19 2.2 2.2 signal
526 Condition Aggravated 508 2.2 2.2 signal
527 Oxygen Saturation Decreased 93 2.2 2.2 signal
528 Facial Paralysis 14 2.2 2.2 signal
529 Neutropenia 223 2.1 2.2 signal
530 Folliculitis 17 2.1 2.1 signal
531 Lymphocyte Count Decreased 29 2.1 2.1 signal
532 Coma 78 2.1 2.1 signal
533 Productive Cough 77 2.1 2.1 signal
534 Sensory Loss 13 2.1 2.1 signal
535 Acute Kidney Injury 245 2.1 2.1 signal
536 Hyponatraemia 90 2.1 2.1 signal
537 Gastritis 42 2.1 2.1 signal
538 Delirium 55 2.1 2.1 signal
539 Product Prescribing Issue 32 2.0 2.1 signal
540 Cardiac Arrest 130 2.0 2.1 signal
541 Intentional Overdose 99 2.0 2.0 signal
542 Abdominal Pain 361 2.0 2.0 signal
543 Hepatic Cirrhosis 29 2.0 2.0 signal
544 Seizure 178 2.0 2.0 signal
545 Platelet Count Increased 20 2.0 2.0 no signal
546 Dermatitis Bullous 11 2.0 2.0 no signal
547 Refusal Of Treatment By Patient 10 2.0 2.0 no signal
548 Therapy Non-responder 68 2.0 2.0 no signal
549 Hypokalaemia 70 2.0 2.0 no signal
550 Iron Deficiency Anaemia 14 2.0 2.0 no signal
551 Visual Acuity Reduced 51 2.0 2.0 no signal
552 Abdominal Pain Upper 311 2.0 2.0 no signal
553 Lung Disorder 74 2.0 2.0 no signal
554 Adrenal Insufficiency 18 2.0 2.0 no signal
555 Bronchiectasis 10 2.0 2.0 no signal
556 Peritonitis 31 1.9 2.0 no signal
557 Depressed Level Of Consciousness 59 1.9 2.0 no signal
558 Night Sweats 48 1.9 1.9 no signal
559 Blood Sodium Decreased 28 1.9 1.9 no signal
560 Rhinitis 12 1.9 1.9 no signal
561 Electrolyte Imbalance 17 1.9 1.9 no signal
562 Pulmonary Oedema 66 1.9 1.9 no signal
563 Hypoglycaemia 71 1.9 1.9 no signal
564 Lung Infection 23 1.9 1.9 no signal
565 Pharyngitis 18 1.9 1.9 no signal
566 Acute Coronary Syndrome 12 1.9 1.9 no signal
567 Dysarthria 54 1.9 1.9 no signal
568 Mass 20 1.9 1.9 no signal
569 Hypoxia 50 1.9 1.9 no signal
570 Disease Recurrence 68 1.9 1.9 no signal
571 Diplopia 37 1.9 1.9 no signal
572 Mucosal Inflammation 37 1.8 1.9 no signal
573 Duodenal Ulcer 10 1.8 1.8 no signal
574 Haematemesis 36 1.8 1.8 no signal
575 Foetal Exposure During Pregnancy 115 1.8 1.8 no signal
576 Hypertension 298 1.8 1.8 no signal
577 Oedema Peripheral 171 1.8 1.8 no signal
578 Visual Field Defect 10 1.8 1.8 no signal
579 Cholelithiasis 45 1.8 1.8 no signal
580 Spinal Pain 16 1.8 1.8 no signal
581 Haemoglobin Decreased 140 1.8 1.8 no signal
582 Vomiting 636 1.8 1.8 no signal
583 Bacterial Infection 25 1.8 1.8 no signal
584 Haematuria 46 1.7 1.7 no signal
585 Cytopenia 16 1.7 1.7 no signal
586 Dyspepsia 131 1.7 1.7 no signal
587 Suicide Attempt 81 1.7 1.7 no signal
588 Arthralgia 546 1.7 1.7 no signal
589 Abscess 21 1.7 1.7 no signal
590 Diffuse Large B-cell Lymphoma 10 1.7 1.7 no signal
591 Spinal Compression Fracture 11 1.7 1.7 no signal
592 Tachycardia 116 1.7 1.7 no signal
593 Cough 365 1.7 1.7 no signal
594 Ileus 16 1.7 1.7 no signal
595 Lethargy 74 1.7 1.7 no signal
596 Tendonitis 20 1.7 1.7 no signal
597 Cardiomyopathy 19 1.7 1.7 no signal
598 Mania 21 1.7 1.7 no signal
599 Subarachnoid Haemorrhage 13 1.7 1.7 no signal
600 Nail Disorder 11 1.6 1.6 no signal
601 Myelosuppression 43 1.6 1.6 no signal
602 Cholecystitis 15 1.6 1.6 no signal
603 Neuroleptic Malignant Syndrome 15 1.6 1.6 no signal
604 Deafness 33 1.6 1.6 no signal
605 Rash Generalised 33 1.6 1.6 no signal
606 Paralysis 18 1.6 1.6 no signal
607 Cellulitis 63 1.6 1.6 no signal
608 Groin Pain 11 1.6 1.6 no signal
609 Blood Disorder 10 1.6 1.6 no signal
610 Erythema 256 1.6 1.6 no signal
611 White Blood Cell Count Increased 48 1.6 1.6 no signal
612 Gingival Bleeding 17 1.6 1.6 no signal
613 Drug Hypersensitivity 240 1.6 1.6 no signal
614 Herpes Zoster 71 1.6 1.6 no signal
615 Intestinal Obstruction 46 1.6 1.6 no signal
616 Nodule 16 1.6 1.6 no signal
617 Hypomagnesaemia 17 1.6 1.6 no signal
618 Respiratory Depression 15 1.6 1.6 no signal
619 Abdominal Discomfort 203 1.6 1.6 no signal
620 Skin Reaction 17 1.6 1.6 no signal
621 Anhedonia 32 1.6 1.6 no signal
622 Ventricular Tachycardia 20 1.6 1.6 no signal
623 Rash Pruritic 65 1.6 1.6 no signal
624 Therapy Partial Responder 18 1.6 1.6 no signal
625 Blood Thyroid Stimulating Hormone Increased 11 1.6 1.6 no signal
626 Inflammation 61 1.5 1.5 no signal
627 General Physical Health Deterioration 136 1.5 1.5 no signal
628 Hypothermia 12 1.5 1.5 no signal
629 Weight Decreased 330 1.5 1.6 no signal
630 Oedema 64 1.5 1.5 no signal
631 Eyelid Ptosis 12 1.5 1.5 no signal
632 Osteopenia 18 1.5 1.5 no signal
633 Pallor 32 1.5 1.5 no signal
634 Convulsion 68 1.5 1.5 no signal
635 Rash 507 1.5 1.5 no signal
636 Ventricular Fibrillation 13 1.5 1.5 no signal
637 Respiratory Disorder 35 1.5 1.5 no signal
638 Osteoporosis 48 1.5 1.5 no signal
639 Skin Ulcer 30 1.5 1.5 no signal
640 Osteomyelitis 21 1.5 1.5 no signal
641 Chills 136 1.5 1.5 no signal
642 Rash Papular 26 1.5 1.5 no signal
643 Blindness 47 1.5 1.5 no signal
644 Hypercholesterolaemia 11 1.5 1.5 no signal
645 Tenderness 12 1.5 1.5 no signal
646 Autoimmune Disorder 11 1.5 1.5 no signal
647 Mitral Valve Incompetence 13 1.5 1.5 no signal
648 Nausea 903 1.5 1.5 no signal
649 Renal Failure 153 1.5 1.5 no signal
650 Spinal Osteoarthritis 10 1.5 1.5 no signal
651 Cardiomegaly 14 1.5 1.5 no signal
652 Muscle Atrophy 14 1.4 1.5 no signal
653 Hypocalcaemia 21 1.4 1.4 no signal
654 Decreased Appetite 257 1.4 1.5 no signal
655 Economic Problem 17 1.4 1.4 no signal
656 Blood Creatine Phosphokinase Increased 32 1.4 1.4 no signal
657 Pneumonia 353 1.4 1.4 no signal
658 Foot Deformity 12 1.4 1.4 no signal
659 Platelet Count Decreased 115 1.4 1.4 no signal
660 Drug Ineffective For Unapproved Indication 60 1.4 1.4 no signal
661 Cardio-respiratory Arrest 45 1.4 1.4 no signal
662 Coordination Abnormal 15 1.4 1.4 no signal
663 Bedridden 14 1.4 1.4 no signal
664 Myalgia 181 1.4 1.4 no signal
665 Blood Calcium Decreased 12 1.4 1.4 no signal
666 Tooth Infection 14 1.4 1.4 no signal
667 Abortion Induced 10 1.4 1.4 no signal
668 Arteriosclerosis 10 1.4 1.4 no signal
669 Malaise 466 1.4 1.4 no signal
670 Small Intestinal Obstruction 13 1.4 1.4 no signal
671 Disorientation 42 1.4 1.4 no signal
672 Nervous System Disorder 33 1.4 1.4 no signal
673 Anaphylactic Shock 27 1.4 1.4 no signal
674 White Blood Cell Count Decreased 113 1.4 1.4 no signal
675 Hypothyroidism 33 1.3 1.4 no signal
676 Conjunctivitis 19 1.3 1.3 no signal
677 Blood Potassium Decreased 31 1.3 1.3 no signal
678 Sudden Death 11 1.3 1.3 no signal
679 Clostridium Difficile Infection 22 1.3 1.3 no signal
680 Cyanosis 16 1.3 1.3 no signal
681 Metastases To Central Nervous System 13 1.3 1.3 no signal
682 Mydriasis 13 1.3 1.3 no signal
683 Wound Infection 11 1.3 1.3 no signal
684 Unresponsive To Stimuli 26 1.3 1.3 no signal
685 Mental Disorder 44 1.3 1.3 no signal
686 Musculoskeletal Stiffness 88 1.3 1.3 no signal
687 Pneumonia Aspiration 25 1.3 1.3 no signal
688 Product Use In Unapproved Indication 245 1.3 1.3 no signal
689 Pruritus Generalised 22 1.3 1.3 no signal
690 Off Label Use 860 1.3 1.3 no signal
691 Confusional State 160 1.3 1.3 no signal
692 Hypersensitivity 182 1.3 1.3 no signal
693 Headache 614 1.3 1.3 no signal
694 Retinal Detachment 9 1.3 1.3 no signal
695 Tooth Abscess 10 1.3 1.3 no signal
696 Bronchospasm 14 1.3 1.3 no signal
697 Haematotoxicity 9 1.3 1.3 no signal
698 Injection Site Discolouration 12 1.3 1.3 no signal
699 Hyperglycaemia 35 1.3 1.3 no signal
700 Ejection Fraction Decreased 15 1.3 1.3 no signal
701 Febrile Neutropenia 63 1.2 1.2 no signal
702 Poisoning 12 1.2 1.2 no signal
703 Anaphylactic Reaction 52 1.2 1.2 no signal
704 Joint Swelling 114 1.2 1.2 no signal
705 Hypophagia 24 1.2 1.2 no signal
706 Hypotension 187 1.2 1.2 no signal
707 Viral Infection 31 1.2 1.2 no signal
708 Loss Of Consciousness 119 1.2 1.2 no signal
709 Body Temperature Increased 19 1.2 1.2 no signal
710 Vitamin D Deficiency 9 1.2 1.2 no signal
711 Agranulocytosis 17 1.2 1.2 no signal
712 Dermatitis 19 1.2 1.2 no signal
713 Cardiogenic Shock 13 1.2 1.2 no signal
714 Upper Respiratory Tract Infection 42 1.2 1.2 no signal
715 Red Blood Cell Count Decreased 26 1.2 1.2 no signal
716 Device Related Infection 14 1.2 1.2 no signal
717 Lymphoma 14 1.2 1.2 no signal
718 Deep Vein Thrombosis 59 1.2 1.2 no signal
719 Hepatitis C 11 1.2 1.2 no signal
720 Drug Ineffective 1,183 1.2 1.2 no signal
721 Product Use Issue 167 1.2 1.2 no signal
722 Blood Pressure Decreased 59 1.2 1.2 no signal
723 Scab 10 1.1 1.1 no signal
724 Completed Suicide 74 1.1 1.1 no signal
725 Acute Myocardial Infarction 26 1.1 1.1 no signal
726 Atrial Fibrillation 85 1.1 1.1 no signal
727 Dyspnoea 492 1.1 1.1 no signal
728 Haemorrhoids 17 1.1 1.1 no signal
729 Agitation 64 1.1 1.1 no signal
730 End Stage Renal Disease 16 1.1 1.1 no signal
731 Hypoaesthesia Oral 13 1.1 1.1 no signal
732 Blood Potassium Increased 14 1.1 1.1 no signal
733 Maternal Exposure During Pregnancy 76 1.1 1.1 no signal
734 Rash Macular 30 1.1 1.1 no signal
735 Abdominal Distension 89 1.1 1.1 no signal
736 Epilepsy 26 1.1 1.1 no signal
737 Respiratory Tract Infection 22 1.1 1.1 no signal
738 Sputum Discoloured 8 1.1 1.1 no signal
739 Musculoskeletal Chest Pain 13 1.1 1.1 no signal
740 Angioedema 37 1.1 1.1 no signal
741 Hyperlipidaemia 10 1.1 1.1 no signal
742 Rheumatoid Arthritis 94 1.1 1.1 no signal
743 Asthenia 312 1.1 1.1 no signal
744 Laryngitis 9 1.1 1.1 no signal
745 Abdominal Pain Lower 21 1.1 1.1 no signal
746 Respiratory Arrest 23 1.1 1.1 no signal
747 Dyspnoea Exertional 31 1.1 1.1 no signal
748 Oesophagitis 9 1.1 1.1 no signal
749 Diabetes Mellitus 63 1.1 1.1 no signal
750 Heart Rate Decreased 29 1.1 1.1 no signal
751 Abortion Spontaneous 33 1.1 1.1 no signal
752 Decreased Immune Responsiveness 8 1.1 1.1 no signal
753 Ulcer 13 1.1 1.1 no signal
754 Melaena 18 1.1 1.1 no signal
755 Neutrophil Count Decreased 33 1.1 1.1 no signal
756 Influenza 91 1.1 1.1 no signal
757 Arthritis 64 1.1 1.1 no signal
758 Ligament Sprain 8 1.1 1.1 no signal
759 Muscular Weakness 92 1.1 1.1 no signal
760 Paranoia 14 1.1 1.1 no signal
761 Body Temperature Decreased 8 1.0 1.0 no signal
762 Cyst 10 1.0 1.0 no signal
763 Photophobia 15 1.0 1.0 no signal
764 Blister 45 1.0 1.0 no signal
765 Psoriasis 105 1.0 1.0 no signal
766 Haemorrhage Intracranial 12 1.0 1.0 no signal
767 Hypotonia 8 1.0 1.0 no signal
768 Disease Progression 94 1.0 1.0 no signal
769 Activities Of Daily Living Impaired 16 1.0 1.0 no signal
770 Photosensitivity Reaction 13 1.0 1.0 no signal
771 Cytokine Release Syndrome 15 1.0 1.0 no signal
772 Diarrhoea 506 1.0 1.0 no signal
773 Skin Exfoliation 65 1.0 1.0 no signal
774 Dehydration 104 1.0 1.0 no signal
775 Seasonal Allergy 11 1.0 1.0 no signal
776 Osteoarthritis 33 1.0 1.0 no signal
777 Dialysis 11 1.0 1.0 no signal
778 Eyelid Oedema 9 1.0 1.0 no signal
779 Hypoaesthesia 115 1.0 1.0 no signal
780 Bronchitis 57 1.0 1.0 no signal
781 Pruritus 289 1.0 1.0 no signal
782 Constipation 165 1.0 1.0 no signal
783 Joint Stiffness 20 1.0 1.0 no signal
784 Skin Discolouration 35 1.0 1.0 no signal
785 Impaired Healing 25 1.0 1.0 no signal
786 Hallucination, Auditory 12 1.0 1.0 no signal
787 Muscle Rigidity 9 1.0 1.0 no signal
788 Spinal Fracture 15 1.0 1.0 no signal
789 Heart Rate Irregular 17 1.0 1.0 no signal
790 Laboratory Test Abnormal 22 1.0 1.0 no signal
791 Fluid Overload 11 1.0 1.0 no signal
792 Hypoacusis 32 1.0 1.0 no signal
793 Urinary Incontinence 22 1.0 1.0 no signal
794 Skin Laceration 8 1.0 1.0 no signal
795 Schizophrenia 9 1.0 1.0 no signal
796 Spinal Disorder 7 1.0 1.0 no signal
797 Gastric Ulcer 14 1.0 1.0 no signal
798 Dysuria 27 1.0 1.0 no signal
799 Supraventricular Tachycardia 7 1.0 1.0 no signal
800 Secretion Discharge 9 0.9 0.9 no signal
801 Gastrointestinal Haemorrhage 61 0.9 0.9 no signal
802 Multiple Fractures 12 0.9 0.9 no signal
803 Dental Caries 8 0.9 0.9 no signal
804 Thrombotic Microangiopathy 7 0.9 0.9 no signal
805 Hallucination, Visual 15 0.9 0.9 no signal
806 Neck Pain 40 0.9 0.9 no signal
807 Inflammatory Bowel Disease 7 0.9 0.9 no signal
808 Delusion 11 0.9 0.9 no signal
809 Diabetic Ketoacidosis 17 0.9 0.9 no signal
810 Urticaria 118 0.9 0.9 no signal
811 Renal Disorder 33 0.9 0.9 no signal
812 Systemic Lupus Erythematosus 25 0.9 0.9 no signal
813 Intentional Product Use Issue 62 0.9 0.9 no signal
814 Circulatory Collapse 12 0.9 0.9 no signal
815 Upper Limb Fracture 14 0.9 0.9 no signal
816 Somnolence 140 0.9 0.9 no signal
817 Ovarian Cyst 7 0.9 0.9 no signal
818 Peritonitis Bacterial 7 0.9 0.9 no signal
819 Aphasia 21 0.9 0.9 no signal
820 Hypokinesia 10 0.9 0.9 no signal
821 Helicobacter Infection 7 0.9 0.9 no signal
822 Movement Disorder 22 0.9 0.9 no signal
823 Syncope 68 0.9 0.9 no signal
824 Chest Pain 126 0.9 0.9 no signal
825 Local Swelling 12 0.9 0.9 no signal
826 Heart Rate Increased 67 0.9 0.9 no signal
827 Unintended Pregnancy 7 0.9 0.9 no signal
828 Oral Herpes 13 0.9 0.9 no signal
829 Peripheral Swelling 102 0.9 0.9 no signal
830 Cataract 39 0.9 0.9 no signal
831 Decreased Activity 7 0.9 0.9 no signal
832 Peripheral Coldness 9 0.9 0.8 no signal
833 Vision Blurred 89 0.8 0.8 no signal
834 Visual Impairment 80 0.8 0.8 no signal
835 Drug Effective For Unapproved Indication 19 0.8 0.8 no signal
836 Dysstasia 19 0.8 0.8 no signal
837 Wound 18 0.8 0.8 no signal
838 No Therapeutic Response 8 0.8 0.8 no signal
839 Psoriatic Arthropathy 26 0.8 0.8 no signal
840 Pain 397 0.8 0.8 no signal
841 Infection 93 0.8 0.8 no signal
842 Intervertebral Disc Degeneration 6 0.8 0.8 no signal
843 Pemphigus 8 0.8 0.8 no signal
844 Cerebral Haemorrhage 23 0.8 0.8 no signal
845 Pregnancy 13 0.8 0.8 no signal
846 Eye Pain 35 0.8 0.8 no signal
847 Renal Injury 19 0.8 0.8 no signal
848 Foot Fracture 12 0.8 0.8 no signal
849 Pain In Extremity 186 0.8 0.8 no signal
850 Therapeutic Response Decreased 38 0.8 0.8 no signal
851 Urinary Tract Infection 107 0.8 0.8 no signal
852 Subdural Haematoma 9 0.8 0.8 no signal
853 Musculoskeletal Pain 33 0.8 0.8 no signal
854 Cold Sweat 11 0.8 0.8 no signal
855 Diabetes Mellitus Inadequate Control 11 0.8 0.8 no signal
856 Sensory Disturbance 10 0.8 0.8 no signal
857 Gait Disturbance 119 0.8 0.8 no signal
858 Sinus Bradycardia 6 0.8 0.8 no signal
859 Limb Discomfort 19 0.8 0.8 no signal
860 Kidney Infection 12 0.8 0.8 no signal
861 Eye Disorder 20 0.8 0.8 no signal
862 Synovitis 11 0.8 0.8 no signal
863 Tinnitus 28 0.8 0.8 no signal
864 Metastases To Lung 7 0.8 0.8 no signal
865 Pulmonary Congestion 8 0.8 0.8 no signal
866 Gait Inability 20 0.8 0.8 no signal
867 Injection Site Pruritus 40 0.8 0.8 no signal
868 Faeces Discoloured 13 0.8 0.8 no signal
869 Swelling 56 0.8 0.8 no signal
870 Joint Range Of Motion Decreased 8 0.8 0.8 no signal
871 Quality Of Life Decreased 8 0.8 0.8 no signal
872 Motor Dysfunction 6 0.8 0.8 no signal
873 Dizziness 295 0.8 0.8 no signal
874 Dry Throat 6 0.8 0.8 no signal
875 Myoclonus 7 0.8 0.8 no signal
876 Paraesthesia 92 0.8 0.8 no signal
877 Palpitations 68 0.8 0.8 no signal
878 Presyncope 14 0.8 0.8 no signal
879 Acute Myeloid Leukaemia 9 0.8 0.8 no signal
880 Gynaecomastia 18 0.7 0.7 no signal
881 Chronic Kidney Disease 44 0.7 0.7 no signal
882 Influenza Like Illness 47 0.7 0.7 no signal
883 Blindness Unilateral 8 0.7 0.7 no signal
884 Tendon Rupture 7 0.7 0.7 no signal
885 Blood Triglycerides Increased 10 0.7 0.7 no signal
886 Injection Site Extravasation 7 0.7 0.7 no signal
887 Stomatitis 34 0.7 0.7 no signal
888 Cognitive Disorder 26 0.7 0.7 no signal
889 Mobility Decreased 40 0.7 0.7 no signal
890 Toothache 10 0.7 0.7 no signal
891 Myelodysplastic Syndrome 8 0.7 0.7 no signal
892 Menorrhagia 11 0.7 0.7 no signal
893 Drug Exposure During Pregnancy 19 0.7 0.7 no signal
894 Chest Discomfort 56 0.7 0.7 no signal
895 Intervertebral Disc Protrusion 12 0.7 0.7 no signal
896 Gastric Cancer 14 0.7 0.7 no signal
897 Back Pain 127 0.7 0.7 no signal
898 Injection Site Haematoma 8 0.7 0.7 no signal
899 Restlessness 20 0.7 0.7 no signal
900 Haemorrhage 57 0.7 0.7 no signal
901 Oropharyngeal Pain 50 0.7 0.7 no signal
902 Feeling Cold 15 0.7 0.7 no signal
903 Obstructive Airways Disorder 6 0.7 0.7 no signal
904 Localised Infection 13 0.7 0.7 no signal
905 Fatigue 417 0.7 0.7 no signal
906 Bone Density Decreased 17 0.7 0.7 no signal
907 Hyperhidrosis 69 0.7 0.7 no signal
908 Squamous Cell Carcinoma 5 0.7 0.7 no signal
909 Tremor 88 0.7 0.7 no signal
910 Rhinorrhoea 34 0.7 0.7 no signal
911 Sinusitis 54 0.7 0.7 no signal
912 Vertigo 32 0.7 0.7 no signal
913 Sopor 7 0.7 0.7 no signal
914 Musculoskeletal Discomfort 9 0.7 0.7 no signal
915 Feeling Hot 32 0.7 0.7 no signal
916 Dizziness Postural 5 0.7 0.7 no signal
917 Flushing 53 0.7 0.7 no signal
918 Fear 14 0.7 0.7 no signal
919 Blood Pressure Increased 79 0.7 0.7 no signal
920 Irritability 31 0.7 0.7 no signal
921 Blood Cholesterol Increased 24 0.7 0.7 no signal
922 Poor Quality Sleep 11 0.7 0.7 no signal
923 Vitreous Floaters 5 0.7 0.7 no signal
924 Parkinsonism 5 0.7 0.7 no signal
925 Overdose 111 0.7 0.7 no signal
926 Diverticulitis 14 0.7 0.7 no signal
927 Arrhythmia 24 0.7 0.7 no signal
928 Pulmonary Embolism 48 0.7 0.7 no signal
929 Gallbladder Disorder 9 0.7 0.7 no signal
930 Feeding Disorder 10 0.7 0.7 no signal
931 Salivary Hypersecretion 5 0.7 0.7 no signal
932 Chronic Obstructive Pulmonary Disease 26 0.6 0.6 no signal
933 Eczema 25 0.6 0.6 no signal
934 Sluggishness 5 0.6 0.6 no signal
935 Bone Disorder 9 0.6 0.6 no signal
936 Temperature Intolerance 5 0.6 0.6 no signal
937 Bradycardia 26 0.6 0.6 no signal
938 Rib Fracture 10 0.6 0.6 no signal
939 Euphoric Mood 5 0.6 0.6 no signal
940 Arthropathy 27 0.6 0.6 no signal
941 Nasopharyngitis 89 0.6 0.6 no signal
942 Pulmonary Arterial Hypertension 7 0.6 0.6 no signal
943 Weight Increased 107 0.6 0.6 no signal
944 Psychomotor Hyperactivity 8 0.6 0.6 no signal
945 Speech Disorder 25 0.6 0.6 no signal
946 Swelling Face 31 0.6 0.6 no signal
947 Cystitis 15 0.6 0.6 no signal
948 Breast Pain 5 0.6 0.6 no signal
949 Dementia 13 0.6 0.6 no signal
950 Lower Respiratory Tract Infection 21 0.6 0.6 no signal
951 Loss Of Personal Independence In Daily Activities 22 0.6 0.6 no signal
952 Injection Site Erythema 57 0.6 0.6 no signal
953 Anxiety 131 0.6 0.6 no signal
954 Pollakiuria 19 0.6 0.6 no signal
955 Neuralgia 11 0.6 0.6 no signal
956 Adverse Reaction 6 0.6 0.6 no signal
957 Ankle Fracture 7 0.6 0.6 no signal
958 Abnormal Behaviour 18 0.6 0.6 no signal
959 Angina Pectoris 13 0.6 0.6 no signal
960 Sars-cov-2 Test Positive 6 0.6 0.6 no signal
961 Product Availability Issue 10 0.6 0.6 no signal
962 Nasal Congestion 26 0.6 0.6 no signal
963 Incorrect Product Administration Duration 9 0.6 0.6 no signal
964 Depression 101 0.6 0.6 no signal
965 Mood Altered 12 0.6 0.6 no signal
966 Epistaxis 33 0.6 0.6 no signal
967 Hallucination 33 0.6 0.6 no signal
968 Tooth Loss 9 0.6 0.6 no signal
969 Back Disorder 7 0.6 0.6 no signal
970 Injection Site Rash 13 0.6 0.6 no signal
971 Dysphonia 25 0.6 0.6 no signal
972 Personality Change 4 0.6 0.6 no signal
973 Diarrhoea Haemorrhagic 4 0.6 0.6 no signal
974 Caesarean Section 5 0.6 0.6 no signal
975 Eye Inflammation 4 0.6 0.6 no signal
976 Skin Fissures 8 0.6 0.6 no signal
977 Osteonecrosis 14 0.5 0.5 no signal
978 Drug Effect Decreased 23 0.5 0.5 no signal
979 Dyskinesia 17 0.5 0.5 no signal
980 Skin Haemorrhage 6 0.5 0.5 no signal
981 Type 2 Diabetes Mellitus 14 0.5 0.5 no signal
982 Sleep Disorder 29 0.5 0.5 no signal
983 Apathy 6 0.5 0.5 no signal
984 Alopecia 81 0.5 0.5 no signal
985 Limb Injury 11 0.5 0.5 no signal
986 Muscle Spasticity 5 0.5 0.5 no signal
987 Colon Cancer 6 0.5 0.5 no signal
988 Abasia 10 0.5 0.5 no signal
989 Injection Site Swelling 30 0.5 0.5 no signal
990 Injection Site Irritation 5 0.5 0.5 no signal
991 Nephrolithiasis 18 0.5 0.5 no signal
992 Thirst 7 0.5 0.5 no signal
993 Eye Discharge 4 0.5 0.5 no signal
994 Insomnia 104 0.5 0.5 no signal
995 Injection Site Warmth 8 0.5 0.5 no signal
996 Poor Venous Access 4 0.5 0.5 no signal
997 Haematoma 10 0.5 0.5 no signal
998 Skeletal Injury 4 0.5 0.5 no signal
999 Adverse Drug Reaction 34 0.5 0.5 no signal
1000 Head Injury 12 0.5 0.5 no signal
1001 Injection Site Reaction 26 0.5 0.5 no signal
1002 Nightmare 13 0.5 0.5 no signal
1003 Wheezing 22 0.5 0.5 no signal
1004 Flatulence 21 0.5 0.5 no signal
1005 Mental Impairment 9 0.5 0.5 no signal
1006 Disturbance In Attention 20 0.5 0.5 no signal
1007 Fall 121 0.5 0.5 no signal
1008 Ocular Hyperaemia 17 0.5 0.5 no signal
1009 Lung Neoplasm Malignant 15 0.5 0.5 no signal
1010 Discomfort 22 0.5 0.5 no signal
1011 Coronary Artery Occlusion 5 0.5 0.5 no signal
1012 Lip Swelling 12 0.5 0.5 no signal
1013 Urinary Retention 12 0.5 0.5 no signal
1014 Coronary Artery Disease 11 0.5 0.5 no signal
1015 Suicidal Ideation 33 0.5 0.5 no signal
1016 Sneezing 8 0.5 0.5 no signal
1017 Acne 27 0.5 0.5 no signal
1018 Wrong Technique In Drug Usage Process 13 0.5 0.5 no signal
1019 Dry Eye 17 0.5 0.5 no signal
1020 Covid-19 62 0.5 0.5 no signal
1021 Stress 25 0.5 0.5 no signal
1022 Full Blood Count Decreased 7 0.5 0.5 no signal
1023 Neoplasm 4 0.5 0.5 no signal
1024 Emotional Distress 42 0.4 0.4 no signal
1025 Gastric Haemorrhage 4 0.4 0.4 no signal
1026 Meningioma 5 0.4 0.4 no signal
1027 Inappropriate Schedule Of Product Administration 60 0.4 0.4 no signal
1028 Product Prescribing Error 8 0.4 0.4 no signal
1029 Migraine 32 0.4 0.4 no signal
1030 Balance Disorder 29 0.4 0.4 no signal
1031 Road Traffic Accident 14 0.4 0.4 no signal
1032 Pelvic Pain 6 0.4 0.4 no signal
1033 Bone Loss 5 0.4 0.4 no signal
1034 Burning Sensation 23 0.4 0.4 no signal
1035 Drug Effect Incomplete 12 0.4 0.4 no signal
1036 Ovarian Cancer 3 0.4 0.4 no signal
1037 Depressed Mood 17 0.4 0.4 no signal
1038 Poisoning Deliberate 3 0.4 0.4 no signal
1039 Asthma 36 0.4 0.4 no signal
1040 Pharyngeal Oedema 5 0.4 0.4 no signal
1041 Deformity 3 0.4 0.4 no signal
1042 Increased Appetite 6 0.4 0.4 no signal
1043 Inappropriate Schedule Of Drug Administration 23 0.4 0.4 no signal
1044 Glycosylated Haemoglobin Increased 8 0.4 0.4 no signal
1045 Dysphagia 30 0.4 0.4 no signal
1046 Laceration 3 0.4 0.4 no signal
1047 Therapy Cessation 16 0.4 0.4 no signal
1048 Myocardial Infarction 55 0.4 0.4 no signal
1049 Ill-defined Disorder 19 0.4 0.4 no signal
1050 Affect Lability 3 0.4 0.4 no signal
1051 Bone Pain 18 0.4 0.4 no signal
1052 Medication Error 17 0.4 0.4 no signal
1053 Hand Deformity 4 0.4 0.4 no signal
1054 Contusion 29 0.4 0.4 no signal
1055 Blood Glucose Increased 57 0.4 0.4 no signal
1056 Muscle Spasms 55 0.4 0.4 no signal
1057 Memory Impairment 41 0.4 0.4 no signal
1058 Hospitalisation 45 0.4 0.4 no signal
1059 Akathisia 4 0.4 0.4 no signal
1060 Injection Site Discomfort 3 0.4 0.4 no signal
1061 Injection Site Haemorrhage 23 0.4 0.4 no signal
1062 Drug Administration Error 9 0.4 0.4 no signal
1063 Intentional Product Misuse 25 0.4 0.4 no signal
1064 Knee Arthroplasty 6 0.4 0.4 no signal
1065 Metastases To Liver 5 0.4 0.4 no signal
1066 Death 244 0.4 0.4 no signal
1067 Incorrect Drug Administration Duration 8 0.4 0.4 no signal
1068 Ischaemic Stroke 5 0.4 0.4 no signal
1069 Hot Flush 21 0.4 0.4 no signal
1070 Fluid Retention 14 0.4 0.4 no signal
1071 Thrombosis 22 0.4 0.4 no signal
1072 Erectile Dysfunction 7 0.4 0.4 no signal
1073 Injection Site Mass 10 0.4 0.4 no signal
1074 Cerebrovascular Accident 46 0.4 0.4 no signal
1075 Eye Swelling 10 0.4 0.4 no signal
1076 Injection Site Pain 82 0.4 0.3 no signal
1077 Illness 27 0.3 0.3 no signal
1078 Sedation 7 0.3 0.3 no signal
1079 Adverse Event 24 0.3 0.3 no signal
1080 Pain Of Skin 7 0.3 0.3 no signal
1081 Aggression 13 0.3 0.3 no signal
1082 Incorrect Dose Administered 57 0.3 0.3 no signal
1083 Blood Glucose Decreased 12 0.3 0.3 no signal
1084 Accidental Overdose 9 0.3 0.3 no signal
1085 Intentional Drug Misuse 5 0.3 0.3 no signal
1086 Vaginal Haemorrhage 10 0.3 0.3 no signal
1087 Cardiac Disorder 22 0.3 0.3 no signal
1088 Skin Cancer 5 0.3 0.3 no signal
1089 Injection Site Induration 3 0.3 0.3 no signal
1090 Amnesia 15 0.3 0.3 no signal
1091 Feeling Abnormal 55 0.3 0.3 no signal
1092 Nervousness 12 0.3 0.3 no signal
1093 Neoplasm Progression 8 0.3 0.3 no signal
1094 Injury 16 0.3 0.3 no signal
1095 Menstruation Irregular 6 0.3 0.3 no signal
1096 Neoplasm Malignant 15 0.3 0.3 no signal
1097 Device Malfunction 15 0.3 0.3 no signal
1098 Injection Site Bruising 17 0.3 0.3 no signal
1099 Injection Site Urticaria 5 0.3 0.3 no signal
1100 Dystonia 4 0.3 0.3 no signal
1101 Dysgeusia 15 0.3 0.3 no signal
1102 Gastrooesophageal Reflux Disease 16 0.3 0.3 no signal
1103 Dry Skin 26 0.3 0.3 no signal
1104 Dry Mouth 16 0.3 0.3 no signal
1105 Sickle Cell Anaemia With Crisis 3 0.2 0.2 no signal
1106 Unevaluable Event 14 0.2 0.2 no signal
1107 Amenorrhoea 3 0.2 0.2 no signal
1108 Plasma Cell Myeloma 7 0.2 0.2 no signal
1109 Metrorrhagia 3 0.2 0.2 no signal
1110 Surgery 10 0.2 0.2 no signal
1111 Pancreatic Carcinoma 5 0.2 0.2 no signal
1112 Malignant Neoplasm Progression 17 0.2 0.2 no signal
1113 Product Dose Omission 11 0.2 0.2 no signal
1114 Withdrawal Syndrome 7 0.2 0.2 no signal
1115 Product Administered At Inappropriate Site 3 0.2 0.2 no signal
1116 Therapy Interrupted 11 0.2 0.2 no signal
1117 Drug Dose Omission 25 0.2 0.2 no signal
1118 Breast Cancer Female 4 0.2 0.2 no signal
1119 Intentional Self-injury 3 0.2 0.2 no signal
1120 Product Dose Omission Issue 40 0.2 0.2 no signal
1121 Skin Burning Sensation 9 0.2 0.2 no signal
1122 Device Issue 9 0.1 0.1 no signal
1123 No Adverse Event 17 0.1 0.1 no signal
1124 Wrong Technique In Product Usage Process 18 0.1 0.1 no signal
1125 Bladder Cancer 5 0.1 0.1 no signal
1126 Renal Cancer 4 0.1 0.1 no signal
1127 Incorrect Route Of Drug Administration 3 0.1 0.1 no signal
1128 Device Breakage 3 0.1 0.1 no signal