Drug

Lopinavir And Ritonavir

1,074 flagged reaction(s) · 54,883 total co-reports · max PRR 3,069.3

Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.

	Reaction	Co-reports (a)	PRR	ROR	Signal
1	Hepatic Displacement	16	3,069.3	3,072.9	signal
2	Diaphragmatic Aplasia	17	2,898.8	2,902.4	signal
3	Progressive External Ophthalmoplegia	82	2,677.4	2,693.8	signal
4	Ultrasound Antenatal Screen	51	1,820.1	1,827.1	signal
5	Hiv Wasting Syndrome	15	1,096.2	1,097.4	signal
6	Spinocerebellar Disorder	17	869.6	870.7	signal
7	Total Lung Capacity Increased	95	833.1	839.0	signal
8	Aids Encephalopathy	20	807.7	808.9	signal
9	Cardiac Malposition	23	666.0	667.1	signal
10	Congenital Hepatobiliary Anomaly	9	552.5	552.8	signal
11	Congenital Diaphragmatic Anomaly	9	511.5	511.9	signal
12	Mitochondrial Toxicity	177	427.8	433.4	signal
13	Asthma-chronic Obstructive Pulmonary Disease Overlap Syndrome	95	347.9	350.4	signal
14	Hiv Associated Nephropathy	9	336.9	337.1	signal
15	Alpha 1 Foetoprotein Abnormal	15	270.8	271.1	signal
16	Aids Dementia Complex	9	265.6	265.8	signal
17	Lipodystrophy Acquired	291	246.0	251.5	signal
18	Trisomy 18	51	238.6	239.5	signal
19	Immune Reconstitution Syndrome	137	182.2	184.0	signal
20	Neurodevelopmental Disorder	64	162.1	162.8	signal
21	Bone Demineralisation	97	156.5	157.7	signal
22	Kaposi's Sarcoma	42	139.8	140.2	signal
23	Hiv-associated Neurocognitive Disorder	9	135.4	135.5	signal
24	Cushing's Syndrome	56	134.3	134.8	signal
25	Ergot Poisoning	10	133.4	133.5	signal
26	Deformity Thorax	15	130.1	130.2	signal
27	Acquired Immunodeficiency Syndrome	39	127.6	128.0	signal
28	Burkitt's Lymphoma	8	126.6	126.6	signal
29	Rickets	14	122.8	122.9	signal
30	Pneumocystis Carinii Pneumonia	15	122.4	122.6	signal
31	Portal Fibrosis	15	118.7	118.8	signal
32	Mitochondrial Cytopathy	31	116.6	116.9	signal
33	Fanconi Syndrome Acquired	121	115.6	116.6	signal
34	Ultrasound Antenatal Screen Abnormal	15	112.3	112.4	signal
35	Congenital Hearing Disorder	11	111.8	111.9	signal
36	Adrenogenital Syndrome	9	110.5	110.6	signal
37	Cerebellar Hypoplasia	11	107.5	107.6	signal
38	Hydrops Foetalis	39	105.9	106.2	signal
39	Psychiatric Decompensation	121	102.9	103.8	signal
40	Cd4 Lymphocytes Abnormal	12	94.0	94.0	signal
41	Trisomy 21	72	93.7	94.2	signal
42	Human Immunodeficiency Virus Transmission	14	88.4	88.5	signal
43	Double Outlet Right Ventricle	15	81.9	82.0	signal
44	Polydactyly	56	79.4	79.7	signal
45	Exomphalos	26	78.4	78.5	signal
46	Jaundice Cholestatic	168	77.5	78.5	signal
47	Hypomania	172	76.1	77.1	signal
48	Skull Malformation	30	75.1	75.3	signal
49	Psychomotor Skills Impaired	118	73.1	73.8	signal
50	Encephalocele	11	70.9	71.0	signal
51	Cd4 Lymphocytes Increased	10	68.8	68.9	signal
52	Congenital Choroid Plexus Cyst	13	68.8	68.9	signal
53	Dandy-walker Syndrome	11	68.6	68.7	signal
54	Stillbirth	202	67.5	68.5	signal
55	Placental Infarction	9	64.8	64.9	signal
56	Cleft Lip And Palate	45	64.6	64.8	signal
57	Fanconi Syndrome	56	64.6	64.8	signal
58	Kidney Malformation	14	63.4	63.4	signal
59	Low Set Ears	16	62.2	62.2	signal
60	Intra-uterine Death	62	61.6	61.9	signal
61	Facial Wasting	10	60.7	60.7	signal
62	Cerebral Toxoplasmosis	34	58.7	58.8	signal
63	Hyperferritinaemia	15	58.4	58.5	signal
64	Lipoatrophy	34	57.8	58.0	signal
65	Ophthalmoplegia	56	57.4	57.7	signal
66	Glucose-6-phosphate Dehydrogenase Deficiency	8	55.8	55.8	signal
67	Meningomyelocele	21	55.8	55.8	signal
68	Foetal Cardiac Disorder	11	55.7	55.8	signal
69	Depression Suicidal	117	54.4	54.9	signal
70	Depressive Symptom	118	54.1	54.5	signal
71	Foetal Arrhythmia	9	53.3	53.4	signal
72	Cerebral Ventricle Dilatation	38	52.7	52.9	signal
73	Congenital Skin Dimples	8	52.7	52.7	signal
74	Renal Tubular Disorder	92	52.2	52.6	signal
75	Extraocular Muscle Paresis	15	51.8	51.9	signal
76	Plagiocephaly	16	51.3	51.3	signal
77	Porphyria Non-acute	14	51.2	51.2	signal
78	Congenital Hydrocephalus	16	50.1	50.2	signal
79	Hypouricaemia	9	49.5	49.5	signal
80	Cholestasis Of Pregnancy	14	49.2	49.2	signal
81	Chronic Hepatitis C	12	48.7	48.8	signal
82	Congenital Nose Malformation	16	47.8	47.8	signal
83	Foetal Growth Retardation	23	46.4	46.5	signal
84	Lipohypertrophy	18	46.2	46.3	signal
85	Clinodactyly	8	46.2	46.2	signal
86	Tearfulness	123	45.6	46.0	signal
87	Placental Disorder	27	45.4	45.5	signal
88	Neural Tube Defect	20	44.2	44.3	signal
89	Blighted Ovum	11	44.2	44.2	signal
90	Cd4 Lymphocytes Decreased	59	43.7	43.9	signal
91	Neonatal Aspiration	9	43.3	43.3	signal
92	Anencephaly	15	42.0	42.1	signal
93	Placental Insufficiency	21	41.5	41.6	signal
94	Cryptorchism	29	41.2	41.3	signal
95	Anogenital Warts	23	40.9	41.0	signal
96	Premature Rupture Of Membranes	62	40.9	41.1	signal
97	Hiv Infection	77	40.7	40.9	signal
98	Hypertriglyceridaemia	146	39.9	40.4	signal
99	Syphilis	18	39.5	39.5	signal
100	Osteomalacia	38	38.9	39.0	signal
101	Oesophageal Atresia	15	38.1	38.2	signal
102	Spina Bifida	50	37.9	38.0	signal
103	Hyperlactacidaemia	62	37.4	37.6	signal
104	Long Qt Syndrome	56	37.0	37.2	signal
105	Genotype Drug Resistance Test Positive	24	36.8	36.9	signal
106	Glycosuria	31	36.5	36.6	signal
107	Gastroschisis	11	36.4	36.4	signal
108	Rhinitis Allergic	101	36.2	36.5	signal
109	Placenta Praevia	18	36.1	36.2	signal
110	Viral Load Increased	88	35.9	36.1	signal
111	Drug Exposure During Pregnancy	777	35.8	38.0	signal
112	Virologic Failure	119	35.1	35.4	signal
113	Pyelocaliectasis	20	34.1	34.2	signal
114	Anaemia Neonatal	10	32.8	32.8	signal
115	Umbilical Cord Abnormality	11	32.8	32.8	signal
116	Blood Hiv Rna Increased	37	32.8	32.9	signal
117	Sarcoidosis	98	32.8	33.0	signal
118	Microcephaly	26	32.5	32.6	signal
119	Abortion Induced	192	32.3	32.8	signal
120	Toxoplasmosis	22	32.2	32.3	signal
121	Folate Deficiency	23	31.9	31.9	signal
122	Blood Cortisol Decreased	13	31.8	31.8	signal
123	Arnold-chiari Malformation	19	31.4	31.4	signal
124	Nasal Polyps	95	31.2	31.5	signal
125	Renal Tubular Acidosis	43	31.2	31.3	signal
126	Coarctation Of The Aorta	19	30.9	31.0	signal
127	Hellp Syndrome	12	30.8	30.8	signal
128	Anhedonia	510	30.5	31.7	signal
129	Volvulus	44	29.9	30.0	signal
130	Schizophrenia	227	29.6	30.1	signal
131	Pneumocystis Jiroveci Pneumonia	42	29.5	29.6	signal
132	Congenital Musculoskeletal Anomaly	8	28.4	28.4	signal
133	Meningitis Cryptococcal	31	28.4	28.4	signal
134	Polyhydramnios	18	28.0	28.0	signal
135	Cytomegalovirus Chorioretinitis	34	27.9	28.0	signal
136	Cytolytic Hepatitis	59	27.7	27.8	signal
137	Eyelid Ptosis	176	27.4	27.7	signal
138	Ear Malformation	8	27.0	27.1	signal
139	Cardiac Murmur	148	26.9	27.2	signal
140	Atrioventricular Septal Defect	8	26.6	26.6	signal
141	Dysmorphism	40	26.6	26.6	signal
142	Hodgkin's Disease	12	25.8	25.8	signal
143	Premature Labour	91	25.2	25.4	signal
144	Fat Tissue Increased	23	25.0	25.1	signal
145	Mycobacterium Avium Complex Infection	42	24.9	25.0	signal
146	Neonatal Asphyxia	11	24.5	24.5	signal
147	Foetal Disorder	13	24.3	24.3	signal
148	Visceral Leishmaniasis	11	24.3	24.3	signal
149	Anal Cancer	15	24.3	24.3	signal
150	Pneumococcal Infection	9	24.2	24.2	signal
151	Congenital Hydronephrosis	11	24.2	24.2	signal
152	Superinfection Bacterial	12	23.9	24.0	signal
153	Blood Amylase Increased	26	23.6	23.7	signal
154	Blood Lactic Acid Increased	78	23.5	23.6	signal
155	Dyslipidaemia	74	23.0	23.1	signal
156	Chlamydial Infection	11	22.9	22.9	signal
157	Bronchiectasis	96	22.7	22.9	signal
158	Atypical Mycobacterial Infection	20	22.7	22.7	signal
159	Adrenal Suppression	12	22.4	22.4	signal
160	Foetal Heart Rate Abnormal	13	22.1	22.2	signal
161	Osteopenia	214	22.1	22.5	signal
162	Congenital Central Nervous System Anomaly	15	21.9	22.0	signal
163	Transposition Of The Great Vessels	11	21.9	21.9	signal
164	Economic Problem	211	21.6	21.9	signal
165	Premature Separation Of Placenta	21	21.4	21.4	signal
166	Nephritis Interstitial	17	20.9	20.9	signal
167	Ventricular Septal Defect	76	20.8	20.9	signal
168	Immune Reconstitution Inflammatory Syndrome	66	20.8	20.9	signal
169	Hepatosplenomegaly	34	20.8	20.8	signal
170	T-lymphocyte Count Decreased	9	20.8	20.8	signal
171	Death Neonatal	18	20.6	20.6	signal
172	Viral Mutation Identified	48	20.4	20.4	signal
173	Skeletal Injury	135	20.3	20.5	signal
174	Non-hodgkin's Lymphoma	17	20.1	20.2	signal
175	Foetal Distress Syndrome	27	20.1	20.1	signal
176	Nodular Regenerative Hyperplasia	9	19.9	19.9	signal
177	Pulmonary Valve Stenosis	10	19.6	19.6	signal
178	Lymph Node Tuberculosis	9	19.1	19.1	signal
179	Sick Sinus Syndrome	14	18.9	18.9	signal
180	Osteoporotic Fracture	23	18.8	18.8	signal
181	Twin Pregnancy	10	18.6	18.7	signal
182	Complications Of Maternal Exposure To Therapeutic Drugs	8	18.3	18.3	signal
183	Talipes	36	18.2	18.3	signal
184	Live Birth	96	18.1	18.3	signal
185	Cytogenetic Abnormality	13	18.0	18.0	signal
186	Premature Baby	342	17.8	18.3	signal
187	Multiple-drug Resistance	35	17.8	17.8	signal
188	Maternal Drugs Affecting Foetus	87	17.6	17.7	signal
189	Alpha 1 Foetoprotein Increased	8	17.6	17.6	signal
190	Foetal Death	58	17.6	17.7	signal
191	Caesarean Section	130	17.4	17.5	signal
192	Blood Bilirubin Increased	297	17.2	17.6	signal
193	Hepatotoxicity	243	17.2	17.5	signal
194	Foetal Malformation	12	17.2	17.2	signal
195	Bone Loss	166	17.2	17.4	signal
196	Small For Dates Baby	53	16.7	16.8	signal
197	Immunosuppressant Drug Level Increased	35	16.7	16.7	signal
198	Oesophageal Candidiasis	42	16.7	16.7	signal
199	Abortion Spontaneous	427	16.7	17.2	signal
200	Bone Density Decreased	335	16.6	17.0	signal
201	Congenital Anomaly	82	16.5	16.6	signal
202	Cystitis Noninfective	14	16.4	16.4	signal
203	Nephrogenic Diabetes Insipidus	12	16.4	16.4	signal
204	Psychotic Disorder	305	16.2	16.6	signal
205	Cachexia	51	15.6	15.7	signal
206	Patent Ductus Arteriosus	39	15.3	15.4	signal
207	Normal Newborn	53	15.3	15.4	signal
208	Portal Hypertension	30	15.3	15.3	signal
209	Osteoporosis	400	15.3	15.7	signal
210	Pre-eclampsia	46	15.2	15.3	signal
211	Opportunistic Infection	18	15.2	15.3	signal
212	Hypospadias	20	15.2	15.2	signal
213	Multiple Fractures	160	15.2	15.3	signal
214	Pulmonary Tuberculosis	41	15.1	15.1	signal
215	Varices Oesophageal	29	15.1	15.1	signal
216	Fungal Sepsis	8	15.0	15.0	signal
217	Neonatal Disorder	15	14.8	14.8	signal
218	Brain Herniation	28	14.7	14.7	signal
219	Cryptococcosis	15	14.6	14.6	signal
220	Foetal Growth Restriction	56	14.6	14.6	signal
221	Foetal Exposure During Pregnancy	753	14.5	15.4	signal
222	Hypertransaminasaemia	63	14.5	14.6	signal
223	Hyperbilirubinaemia	93	14.2	14.3	signal
224	Hypophosphataemia	66	14.1	14.2	signal
225	Blood Alkaline Phosphatase Abnormal	8	14.0	14.0	signal
226	Blood Bicarbonate Decreased	17	14.0	14.0	signal
227	Drug Interaction	1,337	13.2	14.6	signal
228	Mechanical Ventilation	16	13.1	13.1	signal
229	Blood Phosphorus Decreased	30	12.9	13.0	signal
230	Psychomotor Retardation	23	12.9	12.9	signal
231	Hepatitis Fulminant	24	12.7	12.7	signal
232	Oligohydramnios	27	12.6	12.7	signal
233	Central Nervous System Lymphoma	11	12.6	12.6	signal
234	Lip Discolouration	10	12.5	12.5	signal
235	Hydrocephalus	43	12.4	12.4	signal
236	Glucose Urine Present	10	12.4	12.4	signal
237	Drug Exposure Before Pregnancy	8	12.3	12.3	signal
238	Cholelithiasis	256	12.2	12.5	signal
239	Bilirubin Conjugated Increased	18	12.1	12.2	signal
240	Faeces Pale	17	12.0	12.0	signal
241	Hepatitis Cholestatic	46	12.0	12.1	signal
242	Hepatocellular Injury	108	11.9	12.0	signal
243	Osteonecrosis	251	11.9	12.1	signal
244	Mixed Liver Injury	22	11.8	11.9	signal
245	Endotracheal Intubation	21	11.8	11.8	signal
246	Pneumonia Pneumococcal	11	11.6	11.7	signal
247	Loss Of Personal Independence In Daily Activities	348	11.5	11.7	signal
248	Lung Neoplasm	31	11.3	11.3	signal
249	Ocular Icterus	31	11.2	11.2	signal
250	Calculus Urinary	11	11.2	11.2	signal
251	Breech Presentation	9	11.2	11.2	signal
252	Paranoia	123	11.1	11.2	signal
253	Anaemia Macrocytic	15	11.1	11.1	signal
254	Abortion Missed	9	11.1	11.1	signal
255	Carbon Dioxide Decreased	8	11.0	11.0	signal
256	Hyperlipidaemia	84	11.0	11.0	signal
257	Lipids Increased	14	10.9	10.9	signal
258	Blood Triglycerides Increased	121	10.7	10.8	signal
259	Renal Failure Acute	293	10.7	10.9	signal
260	Diplopia	175	10.5	10.7	signal
261	Hepatomegaly	66	10.5	10.5	signal
262	Gestational Diabetes	31	10.3	10.3	signal
263	Pregnancy	132	10.2	10.3	signal
264	Nephropathy	61	10.2	10.2	signal
265	Bacterial Sepsis	21	10.1	10.1	signal
266	Radius Fracture	15	9.7	9.7	signal
267	Atrial Septal Defect	52	9.7	9.7	signal
268	Renal Colic	14	9.7	9.7	signal
269	Blood Creatine Phosphokinase Mb Increased	8	9.6	9.6	signal
270	Proteinuria	115	9.5	9.6	signal
271	Drug Rash With Eosinophilia And Systemic Symptoms	20	9.5	9.5	signal
272	Renal Tubular Necrosis	59	9.4	9.4	signal
273	Benign Prostatic Hyperplasia	31	9.4	9.4	signal
274	End Stage Renal Disease	110	9.3	9.4	signal
275	Neonatal Respiratory Distress Syndrome	21	9.2	9.3	signal
276	Cushingoid	19	9.2	9.2	signal
277	Ectopic Pregnancy	18	9.1	9.1	signal
278	Progressive Multifocal Leukoencephalopathy	48	9.1	9.1	signal
279	Paresis	13	9.1	9.1	signal
280	Hepatocellular Damage	13	8.9	8.9	signal
281	Cleft Palate	11	8.9	8.9	signal
282	Renal Injury	170	8.9	9.0	signal
283	Chronic Kidney Disease	431	8.8	9.1	signal
284	Idiopathic Thrombocytopenic Purpura	9	8.8	8.8	signal
285	Hepatic Cytolysis	68	8.7	8.7	signal
286	Cell Death	11	8.7	8.7	signal
287	Bronchopneumonia	19	8.6	8.6	signal
288	Acute Abdomen	8	8.5	8.5	signal
289	Pathogen Resistance	49	8.4	8.4	signal
290	Lobar Pneumonia	10	8.3	8.3	signal
291	Gamma-glutamyltransferase Increased	118	8.3	8.4	signal
292	Heart Disease Congenital	19	8.3	8.3	signal
293	Tooth Loss	110	8.2	8.3	signal
294	Abdominal Hernia	24	8.2	8.2	signal
295	Alanine Aminotransferase Abnormal	11	8.2	8.2	signal
296	Acidosis	40	8.2	8.2	signal
297	Cholestasis	98	8.0	8.1	signal
298	Blood Alkaline Phosphatase Increased	127	8.0	8.0	signal
299	Polydipsia	20	7.9	7.9	signal
300	Depression	1,136	7.8	8.4	signal
301	Medication Residue	13	7.8	7.8	signal
302	Diabetes Insipidus	12	7.7	7.8	signal
303	Exposure During Pregnancy	308	7.7	7.9	signal
304	Encephalitis	34	7.7	7.7	signal
305	Candidiasis	20	7.7	7.7	signal
306	Low Birth Weight Baby	39	7.7	7.7	signal
307	Drug Resistance	125	7.6	7.7	signal
308	Protein Urine Present	24	7.6	7.6	signal
309	Aspartate Aminotransferase Increased	254	7.5	7.6	signal
310	Oral Candidiasis	62	7.4	7.5	signal
311	Hepatic Necrosis	18	7.4	7.4	signal
312	Emotional Distress	578	7.4	7.7	signal
313	Anorexia	62	7.4	7.4	signal
314	Hyperuricaemia	19	7.2	7.2	signal
315	Hypovolaemic Shock	22	7.2	7.2	signal
316	Nephropathy Toxic	51	7.2	7.2	signal
317	Decreased Activity	49	7.1	7.2	signal
318	Lymphadenitis	11	7.1	7.1	signal
319	Hepatitis	116	7.1	7.1	signal
320	Gene Mutation	9	7.1	7.1	signal
321	Cytomegalovirus Test Positive	8	7.1	7.1	signal
322	Hepatic Cirrhosis	83	6.9	7.0	signal
323	Staphylococcal Sepsis	22	6.9	6.9	signal
324	Quality Of Life Decreased	59	6.9	6.9	signal
325	Hand Fracture	31	6.8	6.8	signal
326	Hyperparathyroidism Secondary	11	6.8	6.8	signal
327	Patella Fracture	10	6.7	6.7	signal
328	Femoral Neck Fracture	22	6.7	6.7	signal
329	Acute Pulmonary Oedema	24	6.7	6.7	signal
330	Hepatitis C	52	6.6	6.7	signal
331	Dilatation Ventricular	9	6.6	6.6	signal
332	Hepatic Neoplasm Malignant	9	6.6	6.6	signal
333	Lipase Increased	32	6.6	6.6	signal
334	Transaminases Increased	93	6.5	6.6	signal
335	Alanine Aminotransferase Increased	257	6.5	6.6	signal
336	Jaundice	111	6.4	6.5	signal
337	Oral Intake Reduced	10	6.4	6.4	signal
338	Renal Failure	541	6.3	6.5	signal
339	Congestive Cardiomyopathy	17	6.3	6.3	signal
340	Pseudomembranous Colitis	9	6.3	6.3	signal
341	Drug Toxicity	55	6.2	6.2	signal
342	Metabolic Acidosis	122	6.0	6.1	signal
343	Cerebral Ischaemia	20	6.0	6.0	signal
344	Renal Failure Chronic	30	6.0	6.0	signal
345	Splenomegaly	45	6.0	6.0	signal
346	Aphthous Stomatitis	9	6.0	6.0	signal
347	Ileus Paralytic	17	6.0	6.0	signal
348	Hypercholesterolaemia	36	5.9	5.9	signal
349	Atrioventricular Block Complete	25	5.8	5.9	signal
350	Lactic Acidosis	119	5.8	5.8	signal
351	Carotid Artery Stenosis	13	5.8	5.8	signal
352	Blood Creatinine Increased	242	5.8	5.9	signal
353	Vitamin D Deficiency	36	5.8	5.8	signal
354	Normochromic Normocytic Anaemia	11	5.7	5.7	signal
355	Cervical Dysplasia	8	5.7	5.7	signal
356	Histiocytosis Haematophagic	11	5.7	5.7	signal
357	Hepatitis B	22	5.7	5.7	signal
358	Developmental Delay	33	5.7	5.7	signal
359	Rash Morbilliform	10	5.6	5.6	signal
360	Multi-organ Failure	63	5.6	5.6	signal
361	Fibrosis	11	5.6	5.6	signal
362	Glucose Tolerance Impaired	21	5.6	5.6	signal
363	Maternal Exposure During Pregnancy	314	5.6	5.7	signal
364	Lung Consolidation	10	5.5	5.6	signal
365	Guillain-barre Syndrome	17	5.5	5.5	signal
366	Sudden Cardiac Death	12	5.5	5.5	signal
367	Hepatic Enzyme Increased	236	5.4	5.5	signal
368	Anuria	30	5.4	5.4	signal
369	Hepatic Failure	104	5.4	5.4	signal
370	Cholangitis	21	5.3	5.3	signal
371	Protein Total Increased	9	5.3	5.3	signal
372	Low Density Lipoprotein Increased	26	5.3	5.3	signal
373	Blood Creatine Increased	15	5.3	5.3	signal
374	Adrenal Insufficiency	40	5.2	5.2	signal
375	Humerus Fracture	16	5.2	5.2	signal
376	Haemodialysis	28	5.1	5.2	signal
377	Atrioventricular Block Second Degree	10	5.1	5.1	signal
378	Fracture	61	5.0	5.0	signal
379	Renal Impairment	269	5.0	5.1	signal
380	Intraventricular Haemorrhage	8	5.0	5.0	signal
381	Polyuria	26	5.0	5.0	signal
382	Wrist Fracture	38	4.9	5.0	signal
383	Pancytopenia	176	4.9	5.0	signal
384	Biliary Colic	9	4.9	4.9	signal
385	Premature Delivery	50	4.9	4.9	signal
386	Portal Vein Thrombosis	10	4.8	4.8	signal
387	Foot Fracture	59	4.8	4.9	signal
388	Spinal Compression Fracture	26	4.8	4.8	signal
389	Haemorrhagic Diathesis	11	4.8	4.8	signal
390	Nephrotic Syndrome	21	4.8	4.8	signal
391	Strabismus	9	4.8	4.8	signal
392	Tachypnoea	41	4.7	4.7	signal
393	Pancreatitis Acute	67	4.7	4.7	signal
394	Glomerular Filtration Rate Decreased	36	4.6	4.6	signal
395	Tuberculosis	38	4.6	4.6	signal
396	Acute Respiratory Distress Syndrome	52	4.6	4.6	signal
397	Hepatitis Acute	19	4.6	4.6	signal
398	Bone Density Abnormal	11	4.5	4.5	signal
399	Hepatic Encephalopathy	27	4.5	4.5	signal
400	Blood Lactate Dehydrogenase Increased	46	4.5	4.5	signal
401	Failure To Thrive	15	4.5	4.5	signal
402	Hypoalbuminaemia	22	4.5	4.5	signal
403	Electroencephalogram Abnormal	9	4.4	4.4	signal
404	Coronavirus Infection	19	4.4	4.4	signal
405	Liver Disorder	126	4.4	4.5	signal
406	Drug Level Increased	46	4.3	4.3	signal
407	Disseminated Intravascular Coagulation	39	4.3	4.3	signal
408	Pathological Fracture	14	4.3	4.3	signal
409	Rales	16	4.3	4.3	signal
410	Azotaemia	11	4.3	4.3	signal
411	Prescribed Overdose	53	4.3	4.3	signal
412	Pneumonia Bacterial	25	4.3	4.3	signal
413	Creatinine Renal Clearance Decreased	11	4.3	4.3	signal
414	Lymphadenopathy	96	4.2	4.2	signal
415	Rib Fracture	55	4.2	4.2	signal
416	Ankle Fracture	41	4.1	4.1	signal
417	Lumbar Vertebral Fracture	12	4.1	4.1	signal
418	Covid-19 Pneumonia	31	4.1	4.1	signal
419	Blood Uric Acid Increased	15	4.1	4.1	signal
420	Herpes Virus Infection	15	4.0	4.1	signal
421	Priapism	9	4.0	4.0	signal
422	Rhabdomyolysis	108	4.0	4.1	signal
423	Chest X-ray Abnormal	8	4.0	4.0	signal
424	Hepatic Steatosis	48	4.0	4.0	signal
425	Hyperreflexia	9	4.0	4.0	signal
426	Nephrogenic Anaemia	12	4.0	4.0	signal
427	Umbilical Hernia	12	4.0	4.0	signal
428	Nail Discolouration	10	4.0	4.0	signal
429	Duodenal Ulcer	18	4.0	4.0	signal
430	Hydronephrosis	19	4.0	4.0	signal
431	Bone Marrow Failure	52	4.0	4.0	signal
432	Odynophagia	15	4.0	4.0	signal
433	Facial Paresis	9	3.9	3.9	signal
434	Sudden Death	27	3.9	3.9	signal
435	Toxic Epidermal Necrolysis	38	3.9	3.9	signal
436	Maculopathy	9	3.9	3.9	signal
437	Intracranial Pressure Increased	14	3.9	3.9	signal
438	Hepatic Function Abnormal	93	3.9	3.9	signal
439	Cerebral Atrophy	10	3.9	3.9	signal
440	Anxiety	713	3.9	4.1	signal
441	Renal Transplant	9	3.9	3.9	signal
442	Ascites	73	3.9	3.9	signal
443	Inguinal Hernia	15	3.8	3.8	signal
444	Pyelonephritis	21	3.8	3.8	signal
445	Blood Creatine Phosphokinase Increased	71	3.8	3.8	signal
446	Oliguria	15	3.8	3.8	signal
447	Agranulocytosis	44	3.7	3.7	signal
448	Coronary Artery Stenosis	12	3.7	3.7	signal
449	Sleep Terror	10	3.7	3.7	signal
450	Anaemia	451	3.7	3.8	signal
451	Shock Haemorrhagic	19	3.6	3.6	signal
452	Tibia Fracture	11	3.6	3.6	signal
453	Lung Neoplasm Malignant	96	3.6	3.6	signal
454	Incorrect Route Of Product Administration	39	3.6	3.6	signal
455	Respiratory Distress	64	3.6	3.6	signal
456	Granuloma	8	3.6	3.6	signal
457	Electrocardiogram Qt Prolonged	83	3.6	3.6	signal
458	Difficulty In Walking	8	3.6	3.6	signal
459	Liver Function Test Abnormal	67	3.6	3.6	signal
460	Angina Unstable	15	3.6	3.6	signal
461	Nystagmus	12	3.5	3.5	signal
462	Faecal Incontinence	11	3.5	3.5	signal
463	Chronic Obstructive Pulmonary Disease	117	3.5	3.5	signal
464	Lymphopenia	31	3.4	3.4	signal
465	Haemolysis	17	3.4	3.4	signal
466	Gastroenteritis	32	3.4	3.4	signal
467	Lymphoedema	15	3.4	3.4	signal
468	Bundle Branch Block Right	10	3.4	3.4	signal
469	Electrocardiogram Abnormal	17	3.4	3.4	signal
470	Treatment Noncompliance	117	3.4	3.4	signal
471	Prothrombin Time Prolonged	13	3.3	3.4	signal
472	Leukoencephalopathy	8	3.3	3.3	signal
473	Lymphoma	33	3.3	3.3	signal
474	Autoimmune Thyroiditis	8	3.3	3.3	signal
475	Rash Maculo-papular	47	3.3	3.3	signal
476	Malabsorption	11	3.3	3.3	signal
477	Haemolytic Anaemia	19	3.3	3.3	signal
478	Polyneuropathy	25	3.3	3.3	signal
479	Meningitis	14	3.3	3.3	signal
480	Renal Pain	22	3.2	3.2	signal
481	Tubulointerstitial Nephritis	39	3.2	3.3	signal
482	General Physical Condition Abnormal	14	3.2	3.2	signal
483	Grand Mal Convulsion	19	3.2	3.2	signal
484	Hypokalaemia	93	3.2	3.2	signal
485	Stress Fracture	11	3.2	3.2	signal
486	Renal Cyst	16	3.1	3.1	signal
487	Hypotonia	20	3.1	3.1	signal
488	Coagulopathy	33	3.1	3.1	signal
489	Toxic Skin Eruption	20	3.1	3.1	signal
490	Pancreatitis	103	3.0	3.0	signal
491	Exercise Tolerance Decreased	11	3.0	3.0	signal
492	Haematuria	65	3.0	3.0	signal
493	Metabolic Disorder	11	3.0	3.0	signal
494	Cytomegalovirus Infection	31	2.9	2.9	signal
495	Alcoholism	8	2.9	2.9	signal
496	Acute Kidney Injury	282	2.9	2.9	signal
497	Hepatic Lesion	8	2.9	2.9	signal
498	Herpes Simplex	12	2.9	2.9	signal
499	Renal Disorder	86	2.9	2.9	signal
500	Hyperkalaemia	64	2.9	2.9	signal
501	Electrolyte Imbalance	21	2.8	2.8	signal
502	Suicidal Ideation	167	2.8	2.9	signal
503	Hemiparesis	31	2.8	2.8	signal
504	Circulatory Collapse	31	2.8	2.8	signal
505	Dysstasia	53	2.8	2.8	signal
506	Purpura	16	2.8	2.8	signal
507	Blood Cholesterol Increased	84	2.8	2.8	signal
508	Lung Infiltration	16	2.8	2.8	signal
509	Hemiplegia	15	2.8	2.8	signal
510	Bone Disorder	33	2.8	2.8	signal
511	Leukopenia	89	2.8	2.8	signal
512	Dermatitis Exfoliative	9	2.8	2.8	signal
513	Eosinophilia	31	2.8	2.8	signal
514	Mitral Valve Incompetence	20	2.8	2.8	signal
515	Tooth Fracture	19	2.7	2.7	signal
516	General Physical Health Deterioration	198	2.7	2.7	signal
517	Hyperthermia	13	2.7	2.7	signal
518	Aplastic Anaemia	9	2.7	2.7	signal
519	Dysphagia	160	2.6	2.7	signal
520	Wheezing	100	2.6	2.6	signal
521	Atrioventricular Block	13	2.6	2.6	signal
522	Lower Limb Fracture	32	2.6	2.6	signal
523	Gastritis	44	2.6	2.6	signal
524	Bradycardia	88	2.6	2.6	signal
525	Convulsion	96	2.6	2.6	signal
526	Drug-induced Liver Injury	51	2.6	2.6	signal
527	Tricuspid Valve Incompetence	13	2.6	2.6	signal
528	Chromaturia	37	2.6	2.6	signal
529	Hyponatraemia	91	2.5	2.5	signal
530	Dialysis	23	2.5	2.5	signal
531	Myopathy	14	2.5	2.5	signal
532	Abdominal Tenderness	8	2.5	2.5	signal
533	Drug Abuser	10	2.5	2.5	signal
534	Nervous System Disorder	50	2.5	2.5	signal
535	Status Epilepticus	18	2.5	2.5	signal
536	Neurological Symptom	9	2.5	2.5	signal
537	Motor Dysfunction	16	2.5	2.5	signal
538	Hip Arthroplasty	24	2.5	2.5	signal
539	Enterocolitis	9	2.5	2.5	signal
540	Ventricular Extrasystoles	16	2.4	2.4	signal
541	Compression Fracture	8	2.4	2.4	signal
542	Gastrooesophageal Reflux Disease	123	2.4	2.4	signal
543	Refusal Of Treatment By Patient	10	2.4	2.4	signal
544	Stevens-johnson Syndrome	34	2.4	2.4	signal
545	Pyrexia	528	2.4	2.4	signal
546	Urosepsis	14	2.4	2.4	signal
547	Vomiting	711	2.4	2.4	signal
548	Pneumothorax	24	2.4	2.4	signal
549	Clostridium Difficile Colitis	16	2.3	2.3	signal
550	Intervertebral Disc Degeneration	14	2.3	2.3	signal
551	Immunodeficiency	22	2.3	2.3	signal
552	Intentional Product Use Issue	131	2.3	2.3	signal
553	Tumour Lysis Syndrome	13	2.3	2.3	signal
554	Cardiomyopathy	22	2.3	2.3	signal
555	Arteriosclerosis	14	2.3	2.3	signal
556	Blood Pressure Inadequately Controlled	9	2.3	2.3	signal
557	Spinal Osteoarthritis	13	2.3	2.3	signal
558	Oedema Peripheral	180	2.3	2.3	signal
559	Encephalopathy	36	2.3	2.3	signal
560	Haemodynamic Instability	11	2.3	2.3	signal
561	Nephrolithiasis	67	2.3	2.3	signal
562	Subdural Haematoma	21	2.3	2.3	signal
563	Cardiomegaly	18	2.3	2.3	signal
564	Acute Coronary Syndrome	12	2.2	2.2	signal
565	Brain Oedema	18	2.2	2.2	signal
566	Sinus Tachycardia	20	2.2	2.2	signal
567	Pneumocystis Jirovecii Pneumonia	14	2.2	2.2	signal
568	Thrombocytopenia	156	2.2	2.2	signal
569	Septic Shock	60	2.2	2.2	signal
570	Pulmonary Hypertension	29	2.2	2.2	signal
571	Hypocalcaemia	26	2.1	2.1	signal
572	Coronary Artery Disease	42	2.1	2.1	signal
573	Atrial Flutter	11	2.1	2.1	signal
574	Hypoxia	48	2.1	2.1	signal
575	Uterine Leiomyoma	10	2.1	2.1	signal
576	Face Oedema	23	2.1	2.1	signal
577	Cardiac Failure Acute	9	2.1	2.1	signal
578	Muscle Atrophy	17	2.1	2.1	signal
579	Acute Myocardial Infarction	40	2.1	2.1	signal
580	Malnutrition	15	2.1	2.1	signal
581	Upper Limb Fracture	27	2.1	2.1	signal
582	Gastrointestinal Disorder	119	2.1	2.1	signal
583	Sinus Bradycardia	13	2.1	2.1	signal
584	Post-traumatic Stress Disorder	9	2.1	2.1	signal
585	Haemorrhage Intracranial	20	2.1	2.1	signal
586	C-reactive Protein Increased	48	2.1	2.1	signal
587	Optic Neuritis	12	2.0	2.0	signal
588	Hyperthyroidism	19	2.0	2.0	signal
589	Ecchymosis	9	2.0	2.0	no signal
590	Pneumonia	423	2.0	2.1	signal
591	Iron Deficiency Anaemia	12	2.0	2.0	signal
592	Spinal Fracture	26	2.0	2.0	signal
593	Joint Effusion	9	2.0	2.0	no signal
594	Extrasystoles	9	2.0	2.0	no signal
595	Impaired Work Ability	27	2.0	2.0	no signal
596	Rash Generalised	33	2.0	2.0	no signal
597	Acute Hepatic Failure	17	1.9	1.9	no signal
598	Skin Lesion	34	1.9	1.9	no signal
599	Upper Gastrointestinal Haemorrhage	21	1.9	1.9	no signal
600	Diabetes Mellitus	94	1.9	1.9	no signal
601	Laboratory Test Abnormal	36	1.9	1.9	no signal
602	International Normalised Ratio Increased	35	1.9	1.9	no signal
603	Feeling Drunk	9	1.9	1.9	no signal
604	Diarrhoea	775	1.9	1.9	no signal
605	Drug Eruption	21	1.9	1.9	no signal
606	Abdominal Pain	276	1.8	1.9	no signal
607	Pseudomonas Infection	10	1.8	1.8	no signal
608	Erythema Multiforme	11	1.8	1.8	no signal
609	Respiratory Failure	86	1.8	1.8	no signal
610	Subarachnoid Haemorrhage	12	1.8	1.8	no signal
611	Diarrhoea Haemorrhagic	11	1.8	1.8	no signal
612	Oedema	63	1.8	1.8	no signal
613	Sepsis	129	1.8	1.8	no signal
614	Abdominal Distension	120	1.8	1.8	no signal
615	Large Intestine Perforation	8	1.8	1.8	no signal
616	Pulmonary Haemorrhage	9	1.8	1.8	no signal
617	Epilepsy	35	1.8	1.8	no signal
618	Urine Output Decreased	10	1.8	1.8	no signal
619	Candida Infection	19	1.8	1.8	no signal
620	Respiratory Disorder	34	1.8	1.8	no signal
621	Hallucination, Auditory	18	1.8	1.8	no signal
622	Abscess	18	1.8	1.8	no signal
623	Hyperglycaemia	41	1.8	1.8	no signal
624	Pain	693	1.8	1.8	no signal
625	Hip Fracture	36	1.7	1.7	no signal
626	Vasculitis	13	1.7	1.7	no signal
627	Multiple Organ Dysfunction Syndrome	31	1.7	1.7	no signal
628	Haemophagocytic Lymphohistiocytosis	8	1.7	1.7	no signal
629	Neuropathy Peripheral	104	1.7	1.7	no signal
630	Bipolar Disorder	12	1.7	1.7	no signal
631	Shock	25	1.7	1.7	no signal
632	Haemoglobin Decreased	112	1.7	1.7	no signal
633	Eosinophil Count Increased	9	1.7	1.7	no signal
634	Pollakiuria	45	1.7	1.7	no signal
635	Nerve Injury	12	1.7	1.7	no signal
636	Appendicitis	10	1.7	1.7	no signal
637	Generalised Oedema	13	1.6	1.6	no signal
638	Gastric Ulcer	20	1.6	1.6	no signal
639	Dehydration	140	1.6	1.6	no signal
640	Diffuse Large B-cell Lymphoma	8	1.6	1.6	no signal
641	Dermatitis Allergic	13	1.6	1.6	no signal
642	Neutropenia	140	1.6	1.6	no signal
643	Staphylococcal Infection	34	1.6	1.6	no signal
644	Cyanosis	16	1.6	1.6	no signal
645	Interstitial Lung Disease	49	1.6	1.6	no signal
646	Depressed Level Of Consciousness	40	1.6	1.6	no signal
647	Arterial Occlusive Disease	8	1.6	1.6	no signal
648	Respiratory Rate Increased	9	1.6	1.6	no signal
649	Weight Decreased	281	1.6	1.6	no signal
650	Hiatus Hernia	13	1.6	1.6	no signal
651	Nausea	789	1.6	1.6	no signal
652	Leukocytosis	18	1.5	1.6	no signal
653	Ovarian Cyst	10	1.5	1.5	no signal
654	Pallor	27	1.5	1.5	no signal
655	Condition Aggravated	296	1.5	1.5	no signal
656	Mobility Decreased	70	1.5	1.5	no signal
657	Ileus	12	1.5	1.5	no signal
658	Paralysis	14	1.5	1.5	no signal
659	Cyst	12	1.5	1.5	no signal
660	Flank Pain	9	1.5	1.5	no signal
661	Aphasia	29	1.5	1.5	no signal
662	Squamous Cell Carcinoma	9	1.5	1.5	no signal
663	Coronary Artery Occlusion	13	1.5	1.5	no signal
664	Cerebral Infarction	23	1.5	1.5	no signal
665	Acute Respiratory Failure	18	1.5	1.5	no signal
666	Eyelid Oedema	11	1.5	1.5	no signal
667	Coordination Abnormal	13	1.4	1.4	no signal
668	Aspiration	10	1.4	1.4	no signal
669	Osteoarthritis	39	1.4	1.4	no signal
670	Myalgia	155	1.4	1.4	no signal
671	Cardiogenic Shock	13	1.4	1.4	no signal
672	Liver Injury	22	1.4	1.4	no signal
673	Haematemesis	23	1.4	1.4	no signal
674	Vertigo	55	1.4	1.4	no signal
675	Joint Range Of Motion Decreased	12	1.4	1.4	no signal
676	Blood Potassium Decreased	27	1.4	1.4	no signal
677	Blood Urea Increased	15	1.4	1.4	no signal
678	Asthenia	333	1.4	1.4	no signal
679	Body Temperature Increased	18	1.4	1.4	no signal
680	Red Blood Cell Count Decreased	25	1.4	1.4	no signal
681	Unevaluable Event	66	1.4	1.4	no signal
682	Pericardial Effusion	20	1.4	1.4	no signal
683	Herpes Zoster	50	1.4	1.4	no signal
684	Dysuria	32	1.4	1.4	no signal
685	Hepatic Cancer	21	1.3	1.3	no signal
686	Mental Status Changes	24	1.3	1.3	no signal
687	Bacterial Infection	16	1.3	1.3	no signal
688	Coma	41	1.3	1.3	no signal
689	Dysarthria	32	1.3	1.3	no signal
690	Medication Error	47	1.3	1.3	no signal
691	Thirst	15	1.3	1.3	no signal
692	Neuroleptic Malignant Syndrome	10	1.3	1.3	no signal
693	Ataxia	10	1.3	1.3	no signal
694	Cerebral Haemorrhage	30	1.3	1.3	no signal
695	Altered State Of Consciousness	18	1.3	1.3	no signal
696	Acute Myeloid Leukaemia	13	1.3	1.3	no signal
697	Hypophagia	21	1.3	1.3	no signal
698	Abnormal Dreams	23	1.3	1.3	no signal
699	Sciatica	13	1.3	1.3	no signal
700	Inflammation	42	1.3	1.3	no signal
701	Lung Disorder	40	1.3	1.3	no signal
702	Conjunctivitis	15	1.3	1.3	no signal
703	Libido Decreased	10	1.3	1.3	no signal
704	Suicide Attempt	49	1.3	1.3	no signal
705	Body Temperature Decreased	8	1.3	1.3	no signal
706	Disorientation	32	1.3	1.3	no signal
707	Gingival Bleeding	11	1.3	1.3	no signal
708	Pneumonia Aspiration	20	1.2	1.2	no signal
709	Blood Potassium Increased	13	1.2	1.2	no signal
710	Off Label Use	693	1.2	1.3	no signal
711	Eating Disorder	17	1.2	1.2	no signal
712	Myocarditis	9	1.2	1.2	no signal
713	Mania	13	1.2	1.2	no signal
714	Hypothermia	8	1.2	1.2	no signal
715	Bone Pain	46	1.2	1.2	no signal
716	Drug Reaction With Eosinophilia And Systemic Symptoms	20	1.2	1.2	no signal
717	Drug Level Decreased	8	1.2	1.2	no signal
718	Mental Disorder	34	1.2	1.2	no signal
719	Pruritus Generalised	17	1.2	1.2	no signal
720	Drug Dispensing Error	12	1.2	1.2	no signal
721	Platelet Count Decreased	82	1.2	1.2	no signal
722	Mucosal Inflammation	20	1.2	1.2	no signal
723	Retinal Detachment	7	1.2	1.2	no signal
724	Cardio-respiratory Arrest	32	1.2	1.2	no signal
725	Immune System Disorder	10	1.2	1.2	no signal
726	Liver Function Test Increased	16	1.2	1.2	no signal
727	Hypertension	158	1.2	1.2	no signal
728	Sensory Disturbance	12	1.2	1.2	no signal
729	Nocturia	9	1.2	1.2	no signal
730	Gastrointestinal Pain	8	1.1	1.1	no signal
731	Product Use In Unapproved Indication	178	1.1	1.1	no signal
732	Myocardial Infarction	128	1.1	1.1	no signal
733	Central Nervous System Lesion	10	1.1	1.1	no signal
734	Nightmare	25	1.1	1.1	no signal
735	Respiratory Arrest	20	1.1	1.1	no signal
736	Mouth Ulceration	15	1.1	1.1	no signal
737	Type 2 Diabetes Mellitus	24	1.1	1.1	no signal
738	Blindness Unilateral	10	1.1	1.1	no signal
739	Haematocrit Decreased	14	1.1	1.1	no signal
740	White Blood Cell Count Increased	27	1.1	1.1	no signal
741	Fear	19	1.1	1.1	no signal
742	Productive Cough	33	1.1	1.1	no signal
743	Pulmonary Oedema	31	1.1	1.1	no signal
744	Obesity	11	1.1	1.1	no signal
745	Apathy	10	1.1	1.1	no signal
746	Inappropriate Antidiuretic Hormone Secretion	7	1.1	1.1	no signal
747	Intervertebral Disc Protrusion	15	1.1	1.1	no signal
748	Accidental Overdose	25	1.1	1.1	no signal
749	Pulmonary Embolism	65	1.1	1.1	no signal
750	Bacteraemia	8	1.1	1.1	no signal
751	Cardiac Failure	54	1.0	1.0	no signal
752	Hallucination	50	1.0	1.0	no signal
753	Uveitis	9	1.0	1.0	no signal
754	Dyspnoea Exertional	25	1.0	1.0	no signal
755	Tachycardia	59	1.0	1.0	no signal
756	Gait Disturbance	127	1.0	1.0	no signal
757	Incontinence	7	1.0	1.0	no signal
758	Brain Neoplasm	6	1.0	1.0	no signal
759	Nerve Compression	6	1.0	1.0	no signal
760	Drug Administration Error	20	1.0	1.0	no signal
761	Confusional State	104	1.0	1.0	no signal
762	Pharyngitis	8	1.0	1.0	no signal
763	Oesophagitis	7	1.0	1.0	no signal
764	Chills	75	1.0	1.0	no signal
765	Blood Sodium Decreased	12	1.0	1.0	no signal
766	Abdominal Pain Lower	16	1.0	1.0	no signal
767	Visual Acuity Reduced	21	1.0	1.0	no signal
768	Atrial Fibrillation	61	1.0	1.0	no signal
769	Pleural Effusion	38	1.0	1.0	no signal
770	Rash Papular	14	1.0	1.0	no signal
771	Diabetes Mellitus Inadequate Control	11	1.0	1.0	no signal
772	Arrhythmia	29	0.9	0.9	no signal
773	White Blood Cell Count Decreased	66	0.9	0.9	no signal
774	Cardiac Arrest	50	0.9	0.9	no signal
775	Ventricular Tachycardia	10	0.9	0.9	no signal
776	Abnormal Behaviour	24	0.9	0.9	no signal
777	Psychomotor Hyperactivity	10	0.9	0.9	no signal
778	Hypersensitivity	111	0.9	0.9	no signal
779	Hypoaesthesia Oral	9	0.9	0.9	no signal
780	Vaginal Discharge	6	0.9	0.9	no signal
781	Hypothyroidism	19	0.9	0.9	no signal
782	Helicobacter Infection	6	0.9	0.9	no signal
783	Vaginal Haemorrhage	25	0.9	0.9	no signal
784	Euphoric Mood	6	0.9	0.9	no signal
785	Femur Fracture	18	0.9	0.9	no signal
786	Dermatitis	12	0.9	0.9	no signal
787	Decreased Appetite	134	0.9	0.9	no signal
788	Ejection Fraction Decreased	9	0.9	0.9	no signal
789	Hypomagnesaemia	8	0.9	0.9	no signal
790	Neurotoxicity	10	0.9	0.9	no signal
791	Back Pain	133	0.9	0.9	no signal
792	Mass	8	0.9	0.9	no signal
793	Joint Dislocation	6	0.9	0.9	no signal
794	Kidney Infection	11	0.9	0.9	no signal
795	Abasia	14	0.9	0.9	no signal
796	Hypoglycaemia	27	0.9	0.9	no signal
797	Anosmia	8	0.9	0.9	no signal
798	Insomnia	147	0.9	0.9	no signal
799	Depressed Mood	29	0.9	0.9	no signal
800	Road Traffic Accident	23	0.9	0.9	no signal
801	Pulmonary Arterial Hypertension	8	0.9	0.9	no signal
802	Intentional Self-injury	11	0.8	0.8	no signal
803	Melaena	12	0.8	0.8	no signal
804	Febrile Neutropenia	36	0.8	0.8	no signal
805	Blood Thyroid Stimulating Hormone Increased	5	0.8	0.8	no signal
806	Skin Disorder	18	0.8	0.8	no signal
807	Foot Deformity	6	0.8	0.8	no signal
808	Blood Glucose Abnormal	10	0.8	0.8	no signal
809	Speech Disorder	28	0.8	0.8	no signal
810	Bedridden	7	0.8	0.8	no signal
811	Night Sweats	17	0.8	0.8	no signal
812	Scar	9	0.8	0.8	no signal
813	Musculoskeletal Disorder	10	0.8	0.8	no signal
814	Delirium	18	0.8	0.8	no signal
815	Metrorrhagia	9	0.8	0.8	no signal
816	Eye Disorder	17	0.8	0.8	no signal
817	Chest Pain	96	0.8	0.8	no signal
818	Affect Lability	5	0.8	0.8	no signal
819	Agitation	38	0.8	0.8	no signal
820	Tendonitis	8	0.8	0.8	no signal
821	Drug Abuse	43	0.8	0.8	no signal
822	Haemorrhoids	10	0.8	0.8	no signal
823	Decreased Immune Responsiveness	5	0.8	0.8	no signal
824	Peripheral Coldness	7	0.8	0.8	no signal
825	Lung Infection	8	0.8	0.8	no signal
826	Faeces Discoloured	11	0.8	0.8	no signal
827	Palpitations	59	0.8	0.8	no signal
828	Gout	9	0.8	0.8	no signal
829	Disturbance In Attention	27	0.8	0.8	no signal
830	Activities Of Daily Living Impaired	10	0.8	0.8	no signal
831	Presyncope	12	0.8	0.8	no signal
832	Hypoaesthesia	74	0.8	0.8	no signal
833	Rash	214	0.8	0.8	no signal
834	Lethargy	28	0.8	0.8	no signal
835	Neutrophil Count Increased	5	0.8	0.8	no signal
836	Peritonitis	10	0.8	0.8	no signal
837	Dysgeusia	36	0.7	0.7	no signal
838	Rash Pruritic	26	0.7	0.7	no signal
839	Hypokinesia	7	0.7	0.7	no signal
840	Pericarditis	8	0.7	0.7	no signal
841	Colitis	18	0.7	0.7	no signal
842	Abdominal Pain Upper	98	0.7	0.7	no signal
843	Pain In Extremity	140	0.7	0.7	no signal
844	Sleep Apnoea Syndrome	9	0.7	0.7	no signal
845	Hypotension	94	0.7	0.7	no signal
846	Mydriasis	6	0.7	0.7	no signal
847	Somnolence	94	0.7	0.7	no signal
848	Malaise	204	0.7	0.7	no signal
849	Dystonia	9	0.7	0.7	no signal
850	Respiratory Tract Infection	12	0.7	0.7	no signal
851	Gastric Disorder	16	0.7	0.7	no signal
852	Amnesia	30	0.7	0.7	no signal
853	Disability	9	0.7	0.7	no signal
854	Dental Caries	5	0.7	0.7	no signal
855	Adverse Reaction	6	0.7	0.7	no signal
856	Product Use Complaint	7	0.7	0.7	no signal
857	Red Blood Cell Sedimentation Rate Increased	5	0.7	0.7	no signal
858	Syncope	45	0.7	0.7	no signal
859	Gallbladder Disorder	8	0.7	0.7	no signal
860	Product Taste Abnormal	6	0.7	0.7	no signal
861	Ill-defined Disorder	27	0.7	0.7	no signal
862	Synovitis	8	0.7	0.7	no signal
863	Blindness	18	0.7	0.7	no signal
864	Urinary Incontinence	13	0.7	0.7	no signal
865	Myocardial Ischaemia	5	0.7	0.7	no signal
866	Skin Discolouration	20	0.7	0.7	no signal
867	Neoplasm	5	0.7	0.7	no signal
868	Fatigue	336	0.7	0.7	no signal
869	Haematotoxicity	4	0.7	0.7	no signal
870	Drug Ineffective For Unapproved Indication	24	0.7	0.7	no signal
871	Bronchitis	32	0.7	0.7	no signal
872	Sleep Disorder	30	0.7	0.7	no signal
873	Sexual Dysfunction	5	0.7	0.7	no signal
874	Erectile Dysfunction	11	0.7	0.7	no signal
875	Paraesthesia	67	0.7	0.7	no signal
876	Arthralgia	176	0.7	0.7	no signal
877	Flatulence	24	0.7	0.7	no signal
878	Infection	61	0.7	0.7	no signal
879	Memory Impairment	58	0.7	0.7	no signal
880	Loss Of Consciousness	54	0.7	0.7	no signal
881	Posterior Reversible Encephalopathy Syndrome	4	0.7	0.7	no signal
882	Accident	5	0.7	0.7	no signal
883	Deafness	11	0.7	0.7	no signal
884	Myoclonus	5	0.7	0.7	no signal
885	Bronchospasm	6	0.7	0.7	no signal
886	Aggression	21	0.7	0.7	no signal
887	Rectal Haemorrhage	18	0.6	0.6	no signal
888	Dyspnoea	235	0.6	0.6	no signal
889	Headache	260	0.6	0.6	no signal
890	Swelling Face	27	0.6	0.6	no signal
891	Adverse Drug Reaction	37	0.6	0.6	no signal
892	Muscular Weakness	47	0.6	0.6	no signal
893	Tinnitus	19	0.6	0.6	no signal
894	Drug Prescribing Error	8	0.6	0.6	no signal
895	Thrombosis	33	0.6	0.6	no signal
896	Dizziness	202	0.6	0.6	no signal
897	Gastrointestinal Haemorrhage	34	0.6	0.6	no signal
898	No Therapeutic Response	5	0.6	0.6	no signal
899	Tooth Disorder	9	0.6	0.6	no signal
900	Treatment Failure	33	0.6	0.6	no signal
901	Deep Vein Thrombosis	26	0.6	0.6	no signal
902	Poisoning	5	0.6	0.6	no signal
903	Drug Intolerance	38	0.6	0.6	no signal
904	Oxygen Saturation Decreased	22	0.6	0.6	no signal
905	Dry Throat	4	0.6	0.6	no signal
906	Haemoptysis	11	0.6	0.6	no signal
907	Cough	110	0.6	0.6	no signal
908	Ischaemic Stroke	7	0.6	0.6	no signal
909	Rotator Cuff Syndrome	5	0.6	0.6	no signal
910	Folliculitis	4	0.6	0.6	no signal
911	Injection Site Induration	5	0.6	0.6	no signal
912	Basal Cell Carcinoma	6	0.6	0.6	no signal
913	Throat Irritation	17	0.6	0.6	no signal
914	Therapeutic Response Unexpected	17	0.6	0.6	no signal
915	Disease Recurrence	18	0.6	0.6	no signal
916	Asthma	42	0.6	0.6	no signal
917	Rhinorrhoea	24	0.6	0.6	no signal
918	Movement Disorder	12	0.6	0.6	no signal
919	Neuralgia	9	0.6	0.6	no signal
920	Cerebrovascular Accident	63	0.6	0.6	no signal
921	Neutrophil Count Decreased	15	0.6	0.6	no signal
922	Body Height Decreased	4	0.6	0.6	no signal
923	Cardiac Failure Congestive	30	0.6	0.6	no signal
924	Heart Rate Decreased	13	0.6	0.6	no signal
925	Cognitive Disorder	17	0.6	0.6	no signal
926	Ageusia	9	0.6	0.6	no signal
927	Pruritus	136	0.6	0.6	no signal
928	Weight Increased	80	0.6	0.6	no signal
929	Glycosylated Haemoglobin Increased	9	0.6	0.6	no signal
930	Blister	20	0.6	0.6	no signal
931	Cellulitis	18	0.6	0.6	no signal
932	Overdose	76	0.5	0.5	no signal
933	Skin Ulcer	9	0.5	0.5	no signal
934	Stress	25	0.5	0.5	no signal
935	Blood Pressure Decreased	23	0.5	0.5	no signal
936	Metastases To Lung	4	0.5	0.5	no signal
937	Haematoma	9	0.5	0.5	no signal
938	Toxicity To Various Agents	58	0.5	0.5	no signal
939	Myelodysplastic Syndrome	5	0.5	0.5	no signal
940	Cystitis	11	0.5	0.5	no signal
941	Arthritis	27	0.5	0.5	no signal
942	Metastases To Liver	6	0.5	0.5	no signal
943	Neoplasm Progression	12	0.5	0.5	no signal
944	Nasal Congestion	20	0.5	0.5	no signal
945	Madarosis	4	0.5	0.5	no signal
946	Rash Erythematous	16	0.5	0.5	no signal
947	Local Swelling	6	0.5	0.5	no signal
948	Covid-19	60	0.5	0.5	no signal
949	Dyspepsia	33	0.5	0.5	no signal
950	Colon Cancer	5	0.5	0.5	no signal
951	Muscle Rigidity	4	0.5	0.5	no signal
952	Mood Altered	9	0.5	0.5	no signal
953	Viral Infection	11	0.5	0.5	no signal
954	Abdominal Discomfort	55	0.5	0.5	no signal
955	Crying	12	0.5	0.5	no signal
956	Hyperhidrosis	42	0.5	0.5	no signal
957	Transient Ischaemic Attack	11	0.5	0.5	no signal
958	Anger	11	0.5	0.5	no signal
959	Urinary Tract Infection	55	0.5	0.5	no signal
960	Seizure	37	0.5	0.5	no signal
961	Injection Site Reaction	22	0.5	0.5	no signal
962	Eye Inflammation	3	0.5	0.5	no signal
963	Hair Colour Changes	4	0.5	0.5	no signal
964	Blood Glucose Increased	60	0.5	0.5	no signal
965	Rash Macular	11	0.5	0.5	no signal
966	Irritability	19	0.5	0.5	no signal
967	Cardiovascular Disorder	8	0.5	0.5	no signal
968	Hernia	6	0.5	0.5	no signal
969	Drug Dose Omission	52	0.5	0.5	no signal
970	Parkinsonism	3	0.5	0.5	no signal
971	Sedation	8	0.5	0.5	no signal
972	Joint Stiffness	8	0.5	0.5	no signal
973	Pharmaceutical Product Complaint	8	0.5	0.5	no signal
974	Upper Respiratory Tract Infection	14	0.5	0.5	no signal
975	Gait Inability	10	0.5	0.5	no signal
976	Balance Disorder	26	0.5	0.5	no signal
977	Ocular Hyperaemia	14	0.5	0.5	no signal
978	Drug Hypersensitivity	58	0.5	0.5	no signal
979	Hunger	4	0.5	0.5	no signal
980	Limb Injury	8	0.5	0.5	no signal
981	Chest Discomfort	30	0.5	0.5	no signal
982	Death	251	0.5	0.4	no signal
983	Emotional Disorder	9	0.5	0.5	no signal
984	Knee Arthroplasty	6	0.4	0.4	no signal
985	Cardiac Disorder	27	0.4	0.4	no signal
986	Fall	94	0.4	0.4	no signal
987	Tremor	47	0.4	0.4	no signal
988	Angina Pectoris	8	0.4	0.4	no signal
989	Skin Exfoliation	23	0.4	0.4	no signal
990	Panic Attack	10	0.4	0.4	no signal
991	Injection Site Nodule	3	0.4	0.4	no signal
992	Wrong Technique In Drug Usage Process	10	0.4	0.4	no signal
993	Eye Swelling	10	0.4	0.4	no signal
994	Urinary Retention	9	0.4	0.4	no signal
995	Injury	19	0.4	0.4	no signal
996	Neck Pain	15	0.4	0.4	no signal
997	Musculoskeletal Pain	14	0.4	0.4	no signal
998	Vision Blurred	36	0.4	0.4	no signal
999	Eczema	13	0.4	0.4	no signal
1000	Urticaria	43	0.4	0.4	no signal
1001	Hospitalisation	39	0.4	0.4	no signal
1002	Heart Rate Increased	25	0.4	0.4	no signal
1003	Muscle Spasms	46	0.4	0.4	no signal
1004	Therapy Non-responder	11	0.4	0.4	no signal
1005	Restlessness	9	0.4	0.4	no signal
1006	Feeling Hot	15	0.4	0.4	no signal
1007	Impaired Healing	8	0.4	0.4	no signal
1008	Completed Suicide	20	0.4	0.4	no signal
1009	Injection Site Irritation	3	0.4	0.4	no signal
1010	Metastases To Central Nervous System	3	0.4	0.4	no signal
1011	Oesophageal Carcinoma	7	0.4	0.4	no signal
1012	Nervousness	12	0.4	0.4	no signal
1013	Burning Sensation	16	0.4	0.4	no signal
1014	Visual Impairment	28	0.4	0.4	no signal
1015	Sinusitis	23	0.3	0.3	no signal
1016	Gynaecomastia	7	0.3	0.3	no signal
1017	Haemorrhage	23	0.3	0.3	no signal
1018	Arthropathy	12	0.3	0.3	no signal
1019	Stomatitis	13	0.3	0.3	no signal
1020	Intestinal Obstruction	8	0.3	0.3	no signal
1021	Epistaxis	16	0.3	0.3	no signal
1022	Constipation	46	0.3	0.3	no signal
1023	Neoplasm Malignant	14	0.3	0.3	no signal
1024	Hypoacusis	9	0.3	0.3	no signal
1025	Erythema	43	0.3	0.3	no signal
1026	Diabetic Ketoacidosis	5	0.3	0.3	no signal
1027	Meningioma	3	0.3	0.3	no signal
1028	Colitis Ulcerative	9	0.3	0.3	no signal
1029	Product Complaint	5	0.3	0.3	no signal
1030	Extrapyramidal Disorder	5	0.3	0.3	no signal
1031	Eye Pain	11	0.3	0.3	no signal
1032	Influenza	22	0.3	0.3	no signal
1033	Blood Pressure Increased	30	0.3	0.3	no signal
1034	Influenza Like Illness	16	0.3	0.3	no signal
1035	Intentional Drug Misuse	4	0.3	0.3	no signal
1036	Musculoskeletal Stiffness	16	0.3	0.3	no signal
1037	Surgery	10	0.3	0.3	no signal
1038	Hot Flush	13	0.3	0.3	no signal
1039	Cataract	10	0.3	0.3	no signal
1040	Inappropriate Schedule Of Drug Administration	12	0.3	0.3	no signal
1041	Nasopharyngitis	30	0.3	0.3	no signal
1042	Drug Ineffective	209	0.2	0.2	no signal
1043	Feeling Abnormal	38	0.2	0.2	no signal
1044	Fluid Retention	8	0.2	0.2	no signal
1045	Dysphonia	9	0.2	0.2	no signal
1046	Dry Skin	20	0.2	0.2	no signal
1047	Injection Site Pruritus	10	0.2	0.2	no signal
1048	Therapeutic Response Decreased	9	0.2	0.2	no signal
1049	Haematochezia	8	0.2	0.2	no signal
1050	Adverse Event	13	0.2	0.2	no signal
1051	Intentional Product Misuse	12	0.2	0.2	no signal
1052	Injection Site Mass	5	0.2	0.2	no signal
1053	Incorrect Dose Administered	30	0.2	0.2	no signal
1054	Joint Swelling	16	0.2	0.2	no signal
1055	Acne	10	0.2	0.2	no signal
1056	Swelling	12	0.2	0.2	no signal
1057	Disease Progression	15	0.2	0.2	no signal
1058	Intentional Overdose	8	0.2	0.2	no signal
1059	Peripheral Swelling	19	0.2	0.2	no signal
1060	Injection Site Urticaria	3	0.2	0.2	no signal
1061	Dry Mouth	10	0.2	0.2	no signal
1062	Oropharyngeal Pain	11	0.2	0.2	no signal
1063	Gastric Cancer	3	0.2	0.2	no signal
1064	Contusion	11	0.2	0.2	no signal
1065	Alopecia	22	0.2	0.2	no signal
1066	Prostate Cancer	9	0.2	0.2	no signal
1067	Product Use Issue	20	0.2	0.2	no signal
1068	Renal Cancer	5	0.2	0.2	no signal
1069	Drug Withdrawal Syndrome	8	0.1	0.1	no signal
1070	Colorectal Cancer	4	0.1	0.1	no signal
1071	Flushing	8	0.1	0.1	no signal
1072	No Adverse Event	12	0.1	0.1	no signal
1073	Wrong Technique In Product Usage Process	13	0.1	0.1	no signal
1074	Injection Site Pain	17	0.1	0.1	no signal