Reaction

Bone Demineralisation reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,048 reports · 69 co-occurring drugs

As of the last recalculation, Bone Demineralisation appears in 1,048 FAERS reports alongside 69 co-occurring drug terms. The strongest observed disproportionality signal is EMTRICITABINE AND TENOFOVIR DISOPROXIL FUMARATE (PRR 702.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Emtricitabine And Tenofovir Disoproxil Fumarate	636	702.9	712.9
Emtricitabine And Tenofovir Alafenamide	240	545.0	556.8
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	199	484.7	494.5
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	175	463.2	472.4
Dolutegravir Sodium	160	415.6	423.1
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	278	414.3	420.8
Tenofovir Disoproxil Fumarate	292	242.8	245.0
Ritonavir	215	183.6	185.0
Atazanavir	104	159.5	160.6
Lopinavir And Ritonavir	97	156.5	157.7
Raltegravir	110	147.7	148.7
Darunavir	97	140.3	141.2
Abacavir Sulfate	56	120.6	121.3
Zidovudine	74	118.2	118.8
Lamivudine	112	80.5	80.8
Benzonatate	27	33.3	33.3
Azithromycin	58	30.2	30.3
Drs. Clotrimazole	17	29.7	29.7
Family Wellness Clotrimazole	17	29.7	29.7
Clotrimazole Topical	17	29.7	29.7
Azithromycin Monohydrate	58	29.2	29.3
Cephalexin	30	28.3	28.4
Clotrimazole	17	27.9	28.0
Dronabinol	11	27.4	27.5
Methocarbamol Tablets	21	25.4	25.4
Oseltamivir	10	25.2	25.2
Cyclobenzaprine	57	23.9	24.0
Mupirocin	15	22.4	22.4
Mupirocin Calcium	15	22.0	22.0
Oxycodone And Acetaminophen Tablets	13	21.9	21.9
Azithromycin Dihydrate	61	21.9	21.9
Alendronate Sodium Tablet	19	20.7	20.7
Daspone	10	20.6	20.6
Dapsone Gel, 5%	10	20.6	20.6
Dapsone	10	18.8	18.8
Methocarbamol	21	18.7	18.7
Terbinafine Hydrochloride	8	18.0	18.0
Doxepin	9	17.8	17.8
Ritonavir 100 Mg	13	17.5	17.5
Hydroxyzine	39	16.8	16.8
Clindamycin	23	16.4	16.4
Ketoconazole Foam	12	16.3	16.3
Ketoconazole Cream, 2%	12	16.2	16.2
Valacyclovir	33	16.2	16.2
Doxepin Hydrochloride	10	15.9	15.9
Azelastine	14	15.7	15.7
Testosterone Cypionate	7	15.7	15.7
Testosterone	18	15.5	15.6
Doxyclycline Hyclate	13	15.3	15.4
Tizanidine	18	15.2	15.2
Oxycodone And Acetaminophen	17	14.7	14.7
Icosapent Ethyl	6	14.1	14.1
Ketoconazole	12	13.9	13.9
Chlorthalidone	8	13.8	13.8
Bupropion	30	13.7	13.7
Nicotine Polacrilex Mini	10	13.4	13.4
Nicotine Polarilex	10	13.4	13.4
Valacyclovir Hydrochloride	45	13.2	13.2
Meloxicam	36	12.7	12.7
Hydroxyzine Hydrochloride	8	12.2	12.2
Hydroxyzine Hydrochloride Oral	8	12.2	12.2
Umeclidinium	5	11.1	11.1
Oseltamivir Phosphate	13	10.7	10.7
Acetaminophen And Codeine	6	9.8	9.8
Pitavastatin Calcium	5	9.7	9.8
Diclofenac Potassium, Film Coated	3	7.1	7.1
Diclofenac Potassium Tablets	3	7.1	7.1
Mometasone Furoate And Formoterol Fumarate Dihydrate	5	6.4	6.4
Umeclidinium Bromide And Vilanterol Trifenatate	5	6.0	6.0

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.