Reaction
Trisomy 21 reporting signals
As of the last recalculation, Trisomy 21 appears in 1,251 FAERS reports alongside 28 co-occurring drug terms. The strongest observed disproportionality signal is LOPINAVIR AND RITONAVIR (PRR 93.7).
Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
| Drug | Co-reports | PRR | ROR |
|---|---|---|---|
| Lopinavir And Ritonavir | 72 | 93.7 | 94.2 |
| Nevirapine | 47 | 90.0 | 90.5 |
| Zidovudine | 67 | 88.0 | 88.5 |
| Ritonavir 100 Mg | 69 | 81.3 | 81.6 |
| Atazanavir | 55 | 66.6 | 66.8 |
| Ritonavir | 104 | 64.5 | 64.7 |
| Tenofovir Disoproxil Fumarate Tablets | 27 | 53.2 | 53.3 |
| Abacavir Sulfate | 30 | 52.5 | 52.6 |
| Darunavir | 42 | 47.8 | 47.9 |
| Lamivudine Oral | 67 | 46.5 | 46.6 |
| Lamivudine | 72 | 41.1 | 41.2 |
| Labetalol | 24 | 30.5 | 30.6 |
| Raltegravir | 25 | 25.7 | 25.7 |
| Pyrazinamide | 14 | 25.1 | 25.1 |
| Dolutegravir Sodium | 12 | 22.3 | 22.4 |
| Emtricitabine And Tenofovir Disoproxil Fumarate | 58 | 22.1 | 22.2 |
| Tenofovir Disoproxil Fumarate | 33 | 17.0 | 17.0 |
| Rifampin | 13 | 15.0 | 15.0 |
| Levetiracetam In Sodium Chloride | 64 | 14.4 | 14.4 |
| Levetiracetam Oral | 64 | 14.4 | 14.4 |
| Levetiracetam Injection | 64 | 14.4 | 14.4 |
| Hydroxyurea | 16 | 12.7 | 12.7 |
| Isoniazid | 12 | 12.4 | 12.4 |
| Oxcarbazepine | 21 | 10.9 | 10.9 |
| Levetiracetam | 69 | 9.0 | 9.0 |
| Dapagliflozin | 15 | 8.0 | 8.0 |
| Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate | 8 | 7.4 | 7.4 |
| Palivizumab | 6 | 6.5 | 6.5 |