OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Osimertinib

1,041 flagged reaction(s) · 68,809 total co-reports · max PRR 972.5
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Her2 Gene Amplification 9 972.5 972.8 signal
2 Egfr Gene Mutation 152 445.9 448.1 signal
3 Acquired Gene Mutation 473 369.5 375.0 signal
4 Braf V600e Mutation Positive 20 350.5 350.7 signal
5 Drug Resistance Mutation 47 239.9 240.3 signal
6 Malignant Transformation 116 230.0 230.8 signal
7 Non-small Cell Lung Cancer Recurrent 43 120.7 120.9 signal
8 Erythema Dyschromicum Perstans 8 115.3 115.3 signal
9 Braf Gene Mutation 13 110.9 110.9 signal
10 Metastases To Meninges 307 104.4 105.4 signal
11 K-ras Gene Mutation 8 73.1 73.1 signal
12 Malignant Neoplasm Oligoprogression 17 70.7 70.7 signal
13 Tp53 Gene Mutation 8 58.9 59.0 signal
14 Pericardial Effusion Malignant 10 40.0 40.0 signal
15 Metastases To Spinal Cord 11 39.4 39.4 signal
16 Paronychia 225 36.1 36.3 signal
17 Lymphangiosis Carcinomatosa 54 35.9 36.0 signal
18 Metastases To Central Nervous System 658 35.6 36.3 signal
19 Lung Carcinoma Cell Type Unspecified Recurrent 29 32.5 32.6 signal
20 Carcinoembryonic Antigen Increased 90 32.1 32.2 signal
21 Metastases To Adrenals 40 29.9 29.9 signal
22 Non-small Cell Lung Cancer Metastatic 37 29.5 29.6 signal
23 Drug Resistance 1,096 29.3 30.3 signal
24 Metastases To Pleura 44 29.0 29.0 signal
25 Lung Adenocarcinoma Stage Iv 16 28.9 28.9 signal
26 Genital Tract Inflammation 8 28.0 28.0 signal
27 Non-small Cell Lung Cancer Stage Iv 14 26.5 26.6 signal
28 Small Cell Lung Cancer 56 26.2 26.2 signal
29 Thrombophlebitis Migrans 12 25.3 25.3 signal
30 Non-small Cell Lung Cancer 169 24.4 24.5 signal
31 Malignant Pleural Effusion 56 22.6 22.7 signal
32 Malignant Neoplasm Progression 3,354 22.4 24.9 signal
33 Onychoclasis 215 21.2 21.4 signal
34 Gene Mutation 62 21.2 21.2 signal
35 Tumour Compression 9 19.1 19.1 signal
36 Onychalgia 28 18.9 18.9 signal
37 Nail Toxicity 8 18.1 18.1 signal
38 Radiation Pneumonitis 52 16.3 16.4 signal
39 Metastases To The Mediastinum 10 16.2 16.2 signal
40 Metastases To Kidney 13 15.8 15.8 signal
41 Small Cell Carcinoma 8 15.7 15.7 signal
42 Nail Disorder 189 14.6 14.7 signal
43 Metastases To Spleen 9 14.5 14.5 signal
44 Lung Adenocarcinoma 63 14.0 14.0 signal
45 Creatine Kinase Increased 9 14.0 14.0 signal
46 Sars-cov-2 Test Negative 14 13.7 13.7 signal
47 Hydrothorax 16 12.8 12.8 signal
48 Myocardial Injury 19 12.8 12.8 signal
49 Metastases To Pelvis 12 12.7 12.7 signal
50 Brain Cancer Metastatic 13 12.6 12.6 signal
51 Nail Bed Disorder 8 12.5 12.5 signal
52 Metastases To Bone 303 12.4 12.5 signal
53 Metastases To Spine 62 12.4 12.4 signal
54 Hypercreatinaemia 6 12.2 12.2 signal
55 Superior Vena Cava Syndrome 11 12.1 12.2 signal
56 Nail Growth Abnormal 20 12.1 12.1 signal
57 Cardiac Dysfunction 66 12.1 12.1 signal
58 Metastasis 129 12.0 12.1 signal
59 Metastases To Bone Marrow 9 12.0 12.0 signal
60 Dermatitis Acneiform 107 11.8 11.9 signal
61 Radiation Necrosis 9 10.6 10.6 signal
62 Heart Failure With Reduced Ejection Fraction 7 10.2 10.2 signal
63 Lung Opacity 39 10.1 10.1 signal
64 Ingrowing Nail 35 9.9 9.9 signal
65 Pneumonitis 397 9.8 9.9 signal
66 Gene Mutation Identification Test Positive 6 9.4 9.4 signal
67 Skin Toxicity 78 9.3 9.3 signal
68 Metastases To Lung 159 9.2 9.2 signal
69 Metastases To Lymph Nodes 92 9.1 9.2 signal
70 Retroperitoneal Fibrosis 8 9.1 9.1 signal
71 Metastases To Liver 239 9.1 9.1 signal
72 Cutaneous Symptom 9 9.0 9.0 signal
73 Death 11,462 8.9 13.3 signal
74 Lung Carcinoma Cell Type Unspecified Stage Iv 42 8.2 8.2 signal
75 Blood Sodium Abnormal 13 8.2 8.2 signal
76 Interstitial Lung Disease 591 8.1 8.3 signal
77 Nail Infection 17 7.9 7.9 signal
78 Pleural Thickening 8 7.8 7.8 signal
79 Bronchial Carcinoma 9 7.5 7.5 signal
80 Oncologic Complication 11 7.5 7.5 signal
81 Systemic Scleroderma 8 7.4 7.4 signal
82 Lung Cancer Metastatic 31 7.2 7.2 signal
83 Myelosuppression 365 7.1 7.2 signal
84 Pulmonary Artery Thrombosis 8 6.9 6.9 signal
85 Multiple-drug Resistance 32 6.9 6.9 signal
86 Glioblastoma 17 6.7 6.7 signal
87 Brain Neoplasm 90 6.5 6.5 signal
88 Brain Neoplasm Malignant 44 6.5 6.5 signal
89 Ejection Fraction Abnormal 12 6.5 6.5 signal
90 Vocal Cord Paralysis 17 6.3 6.3 signal
91 Tumour Marker Increased 44 6.1 6.1 signal
92 Subacute Cutaneous Lupus Erythematosus 16 6.0 6.0 signal
93 Pleural Effusion 534 5.8 5.9 signal
94 Long Qt Syndrome 20 5.5 5.5 signal
95 Cardiotoxicity 73 5.5 5.5 signal
96 Gastrointestinal Toxicity 38 5.3 5.4 signal
97 Myocardial Necrosis Marker Increased 13 5.3 5.3 signal
98 Metastases To Peritoneum 20 5.3 5.3 signal
99 Blood Alkaline Phosphatase Abnormal 7 5.2 5.2 signal
100 Pulmonary Toxicity 54 5.1 5.1 signal
101 Venous Thrombosis Limb 16 5.1 5.1 signal
102 Dilated Cardiomyopathy 7 5.0 5.0 signal
103 Cancer Pain 19 4.9 4.9 signal
104 Lymphadenopathy Mediastinal 14 4.9 4.9 signal
105 Ejection Fraction Decreased 112 4.8 4.8 signal
106 Shoulder Fracture 11 4.7 4.7 signal
107 Pustule 16 4.6 4.6 signal
108 Hepatic Function Abnormal 245 4.4 4.4 signal
109 Xerosis 8 4.3 4.3 signal
110 Clostridium Colitis 8 4.3 4.3 signal
111 Cardiac Tamponade 31 4.3 4.3 signal
112 Disease Progression 762 4.3 4.4 signal
113 Eastern Cooperative Oncology Group Performance Status Worsened 8 4.3 4.3 signal
114 Recurrent Cancer 26 4.2 4.2 signal
115 Haematotoxicity 59 4.2 4.2 signal
116 Keratitis 19 4.2 4.2 signal
117 Brain Oedema 78 4.1 4.1 signal
118 Lung Neoplasm Malignant 255 4.1 4.1 signal
119 Nail Discolouration 24 4.1 4.1 signal
120 Bone Lesion 22 4.0 4.0 signal
121 Dengue Fever 14 4.0 4.0 signal
122 Infectious Pleural Effusion 9 3.9 3.9 signal
123 Dysentery 11 3.9 3.9 signal
124 Neoplasm 68 3.9 3.9 signal
125 Cardiomyopathy 87 3.9 3.9 signal
126 Pneumothorax 93 3.9 3.9 signal
127 Cardiac Failure Acute 39 3.9 3.9 signal
128 Embolism Arterial 7 3.8 3.8 signal
129 Onycholysis 9 3.8 3.8 signal
130 Aplastic Anaemia 30 3.8 3.8 signal
131 Immune-mediated Lung Disease 10 3.8 3.8 signal
132 Left Ventricular Dysfunction 38 3.8 3.8 signal
133 Cutaneous Lupus Erythematosus 11 3.7 3.7 signal
134 Immune Thrombocytopenia 25 3.7 3.7 signal
135 Pericardial Effusion 128 3.7 3.7 signal
136 Electrocardiogram Qt Prolonged 200 3.7 3.7 signal
137 Feeding Disorder 110 3.6 3.7 signal
138 Torsade De Pointes 43 3.6 3.6 signal
139 Amylase Increased 20 3.6 3.6 signal
140 Eosinophilic Pneumonia 17 3.6 3.6 signal
141 Cerebral Disorder 40 3.6 3.6 signal
142 Ventricular Dysfunction 14 3.6 3.6 signal
143 Hypersensitivity Pneumonitis 6 3.5 3.5 signal
144 Hypertransaminasaemia 36 3.5 3.5 signal
145 Bone Cancer 23 3.5 3.5 signal
146 Pulmonary Pain 15 3.4 3.5 signal
147 Volvulus 12 3.4 3.4 signal
148 Effusion 7 3.4 3.4 signal
149 Onychomycosis 22 3.3 3.3 signal
150 Lung Disorder 245 3.3 3.3 signal
151 Peripheral Artery Thrombosis 7 3.3 3.3 signal
152 Cerebral Thrombosis 14 3.3 3.3 signal
153 Metastatic Neoplasm 21 3.2 3.2 signal
154 Stomatitis 294 3.2 3.2 signal
155 Erythema Multiforme 45 3.2 3.2 signal
156 Skin Wound 8 3.2 3.2 signal
157 Pulmonary Mass 71 3.2 3.2 signal
158 Cardiac Ventricular Thrombosis 6 3.1 3.1 signal
159 Taste Disorder 95 3.1 3.1 signal
160 Hepatic Infection 6 3.1 3.1 signal
161 Performance Status Decreased 22 3.1 3.1 signal
162 Stress Cardiomyopathy 27 3.1 3.1 signal
163 Trichorrhexis 13 3.1 3.1 signal
164 Embolism Venous 14 3.0 3.0 signal
165 Pulmonary Thrombosis 50 3.0 3.0 signal
166 Jugular Vein Thrombosis 8 3.0 3.0 signal
167 Hepatic Cytolysis 55 3.0 3.0 signal
168 Pulmonary Alveolar Haemorrhage 25 2.9 2.9 signal
169 Adenocarcinoma 10 2.9 2.9 signal
170 Skin Fissures 82 2.9 2.9 signal
171 Drug Tolerance 22 2.9 2.9 signal
172 Thrombosis 348 2.8 2.9 signal
173 Alanine Aminotransferase Abnormal 9 2.8 2.8 signal
174 Acute Pulmonary Oedema 24 2.8 2.8 signal
175 Hydrocephalus 23 2.8 2.8 signal
176 Lung Neoplasm 18 2.8 2.8 signal
177 Pneumonia Cytomegaloviral 8 2.7 2.7 signal
178 Nasal Dryness 26 2.7 2.7 signal
179 Panniculitis 10 2.7 2.7 signal
180 Deafness Bilateral 7 2.7 2.7 signal
181 Left Ventricular Failure 14 2.7 2.7 signal
182 Cardiac Fibrillation 6 2.7 2.7 signal
183 Neoplasm Progression 142 2.7 2.7 signal
184 Mouth Ulceration 85 2.7 2.7 signal
185 Skin Atrophy 23 2.6 2.6 signal
186 Central Nervous System Lesion 55 2.6 2.6 signal
187 Computerised Tomogram Abnormal 9 2.6 2.6 signal
188 Blood Sodium Decreased 74 2.6 2.6 signal
189 Granulocyte Count Decreased 7 2.6 2.6 signal
190 Haematological Infection 9 2.6 2.6 signal
191 Onychomadesis 16 2.5 2.5 signal
192 Cerebral Infarction 93 2.5 2.5 signal
193 Thyroiditis 11 2.4 2.4 signal
194 Chapped Lips 16 2.4 2.4 signal
195 Facial Paralysis 31 2.4 2.4 signal
196 Therapy Partial Responder 55 2.4 2.4 signal
197 Hepatic Mass 7 2.4 2.4 signal
198 Skin Disorder 121 2.4 2.4 signal
199 Cerebellar Syndrome 8 2.4 2.4 signal
200 Traumatic Lung Injury 7 2.4 2.4 signal
201 Blood Creatine Phosphokinase Increased 105 2.4 2.4 signal
202 Vocal Cord Disorder 7 2.3 2.3 signal
203 Fracture 67 2.3 2.3 signal
204 Myocarditis 40 2.3 2.3 signal
205 Hepatotoxicity 78 2.3 2.3 signal
206 Mucosal Dryness 7 2.3 2.3 no signal
207 Aortic Arteriosclerosis 9 2.3 2.3 signal
208 Myositis 31 2.3 2.3 signal
209 Decreased Appetite 795 2.3 2.3 signal
210 Ventricular Hypokinesia 11 2.3 2.3 signal
211 Hypophagia 86 2.2 2.2 signal
212 Hepatic Neoplasm 11 2.2 2.2 signal
213 Gastrointestinal Stromal Tumour 9 2.2 2.2 signal
214 Lung Abscess 7 2.2 2.2 no signal
215 Deep Vein Thrombosis 218 2.2 2.2 signal
216 Liver Disorder 147 2.2 2.2 signal
217 Ulcerative Keratitis 9 2.2 2.2 signal
218 Mastication Disorder 10 2.2 2.2 signal
219 Compression Fracture 17 2.2 2.2 signal
220 Embolism 27 2.1 2.1 signal
221 Leukoencephalopathy 12 2.1 2.1 signal
222 Pneumocystis Jirovecii Pneumonia 32 2.1 2.1 signal
223 Physical Deconditioning 8 2.1 2.1 no signal
224 Pulmonary Oedema 142 2.1 2.1 signal
225 Hepatitis B Reactivation 10 2.1 2.1 signal
226 Cardiac Failure 252 2.1 2.1 signal
227 Terminal State 21 2.1 2.1 signal
228 Aphthous Ulcer 24 2.1 2.1 signal
229 Neoplasm Malignant 208 2.1 2.1 signal
230 Vasculitis 36 2.0 2.0 signal
231 Pigmentation Disorder 19 2.0 2.0 signal
232 Pneumonia Bacterial 28 2.0 2.0 signal
233 Dementia 85 2.0 2.0 signal
234 Venous Thrombosis 12 2.0 2.0 signal
235 Suspected Counterfeit Product 12 2.0 2.0 signal
236 Mucosal Inflammation 79 2.0 2.0 no signal
237 Weight Gain Poor 7 2.0 2.0 no signal
238 Platelet Count Decreased 322 2.0 2.0 no signal
239 Atypical Pneumonia 9 2.0 2.0 no signal
240 Pleurisy 18 2.0 2.0 no signal
241 Cytopenia 36 2.0 2.0 no signal
242 Empyema 6 2.0 2.0 no signal
243 Oral Pain 67 2.0 2.0 no signal
244 Dry Skin 391 2.0 2.0 no signal
245 Pulmonary Embolism 281 1.9 1.9 no signal
246 Weight Abnormal 7 1.9 1.9 no signal
247 Appetite Disorder 19 1.9 1.9 no signal
248 Bone Marrow Failure 59 1.9 1.9 no signal
249 Organising Pneumonia 14 1.9 1.9 no signal
250 Meningitis 19 1.9 1.9 no signal
251 Suffocation Feeling 7 1.9 1.9 no signal
252 Cardiac Failure Chronic 12 1.9 1.9 no signal
253 Lung Infiltration 25 1.8 1.9 no signal
254 Hepatitis B 17 1.8 1.8 no signal
255 Oesophageal Stenosis 8 1.8 1.8 no signal
256 Pancreatic Carcinoma Metastatic 8 1.8 1.8 no signal
257 Escherichia Sepsis 8 1.8 1.8 no signal
258 Henoch-schonlein Purpura 6 1.8 1.8 no signal
259 Pancytopenia 153 1.8 1.8 no signal
260 Purpura 24 1.8 1.8 no signal
261 Decreased Activity 29 1.8 1.8 no signal
262 Suspected Covid-19 9 1.8 1.8 no signal
263 Ventricular Fibrillation 30 1.8 1.8 no signal
264 Chronic Gastritis 6 1.8 1.8 no signal
265 Body Height Decreased 29 1.8 1.8 no signal
266 Renal Impairment 224 1.8 1.8 no signal
267 Demyelination 11 1.8 1.8 no signal
268 Tongue Ulceration 9 1.7 1.7 no signal
269 Liver Injury 64 1.7 1.7 no signal
270 Disease Complication 12 1.7 1.7 no signal
271 Diarrhoea 1,677 1.7 1.8 no signal
272 Respiratory Failure 190 1.7 1.7 no signal
273 Hair Growth Abnormal 18 1.7 1.7 no signal
274 Rash Pustular 19 1.7 1.7 no signal
275 Cheilitis 14 1.7 1.7 no signal
276 Dermatitis Exfoliative 13 1.7 1.7 no signal
277 Rhinalgia 7 1.7 1.7 no signal
278 Inappropriate Antidiuretic Hormone Secretion 26 1.7 1.7 no signal
279 Drug-induced Liver Injury 78 1.7 1.7 no signal
280 Hair Texture Abnormal 34 1.7 1.7 no signal
281 Hepatitis 64 1.6 1.6 no signal
282 Rash Vesicular 12 1.6 1.6 no signal
283 Neurological Symptom 14 1.6 1.6 no signal
284 Lymphadenopathy 87 1.6 1.6 no signal
285 Enterocolitis 14 1.6 1.6 no signal
286 Dyspnoea At Rest 7 1.6 1.6 no signal
287 Supraventricular Tachycardia 23 1.6 1.6 no signal
288 Bundle Branch Block Right 11 1.6 1.6 no signal
289 Atrial Fibrillation 232 1.6 1.6 no signal
290 Thoracic Vertebral Fracture 7 1.6 1.6 no signal
291 Cachexia 12 1.5 1.5 no signal
292 Squamous Cell Carcinoma 22 1.5 1.5 no signal
293 Dyschezia 7 1.5 1.5 no signal
294 Neuropathy Peripheral 219 1.5 1.5 no signal
295 Thrombocytopenia 257 1.5 1.5 no signal
296 Deafness 60 1.5 1.5 no signal
297 Neutrophil Count Decreased 92 1.5 1.5 no signal
298 Atelectasis 22 1.5 1.5 no signal
299 Cutaneous Vasculitis 8 1.5 1.5 no signal
300 Ischaemic Stroke 40 1.5 1.5 no signal
301 Retinal Detachment 20 1.4 1.4 no signal
302 Electrolyte Imbalance 25 1.4 1.4 no signal
303 Rash 936 1.4 1.4 no signal
304 Inability To Afford Medication 21 1.4 1.4 no signal
305 Angiopathy 12 1.4 1.4 no signal
306 Haemoptysis 59 1.4 1.4 no signal
307 General Physical Health Deterioration 241 1.4 1.4 no signal
308 Hypoalbuminaemia 16 1.4 1.4 no signal
309 Hepatic Lesion 9 1.4 1.4 no signal
310 Cardiac Disorder 195 1.4 1.4 no signal
311 Nodule 27 1.4 1.4 no signal
312 Haemothorax 6 1.4 1.4 no signal
313 Eating Disorder 44 1.4 1.4 no signal
314 Spinal Cord Compression 8 1.3 1.3 no signal
315 Gingival Swelling 9 1.3 1.3 no signal
316 Immunodeficiency 30 1.3 1.3 no signal
317 Acute Respiratory Distress Syndrome 36 1.3 1.3 no signal
318 Fluid Intake Reduced 10 1.3 1.3 no signal
319 Cardiomegaly 25 1.3 1.3 no signal
320 Mass 28 1.3 1.3 no signal
321 Toxic Epidermal Necrolysis 30 1.3 1.3 no signal
322 Transaminases Increased 44 1.3 1.3 no signal
323 Dysphagia 187 1.3 1.3 no signal
324 Nephropathy Toxic 22 1.3 1.3 no signal
325 Intracranial Pressure Increased 11 1.3 1.3 no signal
326 Blood Magnesium Decreased 17 1.3 1.3 no signal
327 Haemorrhage Subcutaneous 7 1.3 1.3 no signal
328 Phlebitis 10 1.3 1.3 no signal
329 Ulcer 31 1.3 1.3 no signal
330 Acute Respiratory Failure 37 1.3 1.3 no signal
331 Food Intolerance 7 1.3 1.3 no signal
332 Ventricular Arrhythmia 7 1.3 1.3 no signal
333 Full Blood Count Abnormal 20 1.2 1.2 no signal
334 Chemotherapy 7 1.2 1.2 no signal
335 Pulmonary Tuberculosis 8 1.2 1.2 no signal
336 Frustration Tolerance Decreased 15 1.2 1.2 no signal
337 Subarachnoid Haemorrhage 19 1.2 1.2 no signal
338 Myopathy 16 1.2 1.2 no signal
339 Macular Degeneration 22 1.2 1.2 no signal
340 Dehydration 245 1.2 1.2 no signal
341 Pulmonary Fibrosis 35 1.2 1.2 no signal
342 Hepatocellular Injury 26 1.2 1.2 no signal
343 Hepatic Enzyme Abnormal 9 1.2 1.2 no signal
344 Faeces Hard 7 1.2 1.2 no signal
345 Heart Rate Abnormal 10 1.2 1.2 no signal
346 Brain Injury 18 1.2 1.2 no signal
347 Oral Infection 7 1.2 1.2 no signal
348 Spinal Compression Fracture 15 1.2 1.2 no signal
349 Dermatitis 37 1.2 1.2 no signal
350 Lip Dry 16 1.2 1.2 no signal
351 Skin Reaction 25 1.2 1.2 no signal
352 Hip Fracture 57 1.2 1.2 no signal
353 Weight Decreased 495 1.2 1.2 no signal
354 Arrhythmia 84 1.2 1.2 no signal
355 Polyneuropathy 21 1.2 1.2 no signal
356 Therapy Change 17 1.2 1.2 no signal
357 Proteinuria 33 1.2 1.2 no signal
358 Cerebral Atrophy 7 1.2 1.2 no signal
359 Blood Creatinine Abnormal 6 1.1 1.1 no signal
360 Adverse Reaction 23 1.1 1.1 no signal
361 Hospice Care 17 1.1 1.1 no signal
362 Decubitus Ulcer 14 1.1 1.1 no signal
363 Asthenia 645 1.1 1.1 no signal
364 Rash Maculo-papular 38 1.1 1.1 no signal
365 Gastritis Erosive 8 1.1 1.1 no signal
366 Embolic Stroke 6 1.1 1.1 no signal
367 Skin Infection 19 1.1 1.1 no signal
368 Cardiac Flutter 11 1.1 1.1 no signal
369 Glossitis 6 1.1 1.1 no signal
370 Musculoskeletal Chest Pain 26 1.1 1.1 no signal
371 Hemiplegia 14 1.1 1.1 no signal
372 Scab 19 1.1 1.1 no signal
373 Platelet Count Abnormal 10 1.1 1.1 no signal
374 Hepatic Failure 50 1.1 1.1 no signal
375 Cerebrovascular Accident 281 1.1 1.1 no signal
376 Atrioventricular Block Complete 11 1.1 1.1 no signal
377 Drug Eruption 29 1.1 1.1 no signal
378 Liver Function Test Increased 35 1.1 1.1 no signal
379 Lymphocyte Count Decreased 29 1.1 1.1 no signal
380 Lymphopenia 23 1.1 1.1 no signal
381 Ventricular Extrasystoles 17 1.1 1.1 no signal
382 Oral Disorder 12 1.1 1.1 no signal
383 Disseminated Intravascular Coagulation 23 1.1 1.1 no signal
384 Hyponatraemia 91 1.1 1.1 no signal
385 Muscle Spasms 297 1.1 1.1 no signal
386 White Blood Cell Count Decreased 175 1.1 1.1 no signal
387 Cardiogenic Shock 23 1.1 1.1 no signal
388 Cataract 95 1.1 1.1 no signal
389 Aspartate Aminotransferase Increased 85 1.1 1.1 no signal
390 Respiratory Distress 44 1.0 1.0 no signal
391 Oedema 86 1.0 1.0 no signal
392 Skin Ulcer 41 1.0 1.0 no signal
393 Toxic Skin Eruption 16 1.0 1.0 no signal
394 Motor Dysfunction 16 1.0 1.0 no signal
395 Blood Creatine Increased 7 1.0 1.0 no signal
396 Pathological Fracture 8 1.0 1.0 no signal
397 Bowel Movement Irregularity 12 1.0 1.0 no signal
398 Anal Incontinence 14 1.0 1.0 no signal
399 Glomerular Filtration Rate Decreased 19 1.0 1.0 no signal
400 Ocular Discomfort 17 1.0 1.0 no signal
401 Osteonecrosis Of Jaw 39 1.0 1.0 no signal
402 Oral Mucosal Blistering 10 1.0 1.0 no signal
403 Endocarditis 8 1.0 1.0 no signal
404 Hair Disorder 13 1.0 1.0 no signal
405 Femoral Neck Fracture 8 1.0 1.0 no signal
406 Gastric Haemorrhage 18 1.0 1.0 no signal
407 Generalised Oedema 19 1.0 1.0 no signal
408 Cough 428 1.0 1.0 no signal
409 Lung Infection 24 1.0 1.0 no signal
410 Blepharitis 6 1.0 1.0 no signal
411 Aphasia 46 1.0 1.0 no signal
412 Ischaemia 7 1.0 1.0 no signal
413 Pulmonary Congestion 20 1.0 1.0 no signal
414 Dysgraphia 10 1.0 1.0 no signal
415 Brain Fog 22 1.0 1.0 no signal
416 Gingival Pain 12 1.0 1.0 no signal
417 Red Blood Cell Count Decreased 43 1.0 1.0 no signal
418 Fungal Skin Infection 6 1.0 1.0 no signal
419 Seizure 171 1.0 1.0 no signal
420 Creatinine Renal Clearance Decreased 6 1.0 1.0 no signal
421 Dry Eye 72 1.0 1.0 no signal
422 Skin Laceration 16 1.0 1.0 no signal
423 Spinal Osteoarthritis 13 1.0 1.0 no signal
424 Pneumonia 470 1.0 1.0 no signal
425 Blindness 59 1.0 1.0 no signal
426 Ventricular Tachycardia 24 1.0 1.0 no signal
427 Photophobia 27 1.0 1.0 no signal
428 Gastrointestinal Perforation 6 1.0 1.0 no signal
429 Hordeolum 6 0.9 0.9 no signal
430 Leukopenia 71 0.9 0.9 no signal
431 Anaemia 271 0.9 0.9 no signal
432 Congestive Cardiomyopathy 6 0.9 0.9 no signal
433 Duodenal Ulcer 10 0.9 0.9 no signal
434 Femur Fracture 44 0.9 0.9 no signal
435 Alanine Aminotransferase Increased 87 0.9 0.9 no signal
436 Skin Discolouration 65 0.9 0.9 no signal
437 Insurance Issue 21 0.9 0.9 no signal
438 Colon Cancer 21 0.9 0.9 no signal
439 Sudden Death 15 0.9 0.9 no signal
440 Exercise Tolerance Decreased 8 0.9 0.9 no signal
441 Ageusia 35 0.9 0.9 no signal
442 Cerebral Haemorrhage 50 0.9 0.9 no signal
443 Internal Haemorrhage 16 0.9 0.9 no signal
444 Gamma-glutamyltransferase Increased 31 0.9 0.9 no signal
445 Myocardial Ischaemia 16 0.9 0.9 no signal
446 Renal Disorder 65 0.9 0.9 no signal
447 Altered State Of Consciousness 30 0.9 0.9 no signal
448 Coronary Artery Stenosis 7 0.9 0.9 no signal
449 Emphysema 14 0.9 0.9 no signal
450 Renal Cyst 11 0.9 0.9 no signal
451 Sensitive Skin 10 0.9 0.9 no signal
452 Dry Throat 14 0.9 0.9 no signal
453 Oesophagitis 15 0.9 0.9 no signal
454 Spinal Disorder 13 0.9 0.9 no signal
455 Gastric Ulcer 26 0.9 0.9 no signal
456 Pneumonia Aspiration 34 0.9 0.9 no signal
457 Disease Recurrence 65 0.9 0.9 no signal
458 Blood Creatinine Increased 89 0.9 0.9 no signal
459 Gait Inability 45 0.9 0.9 no signal
460 Blood Iron Decreased 16 0.9 0.9 no signal
461 Skin Mass 9 0.9 0.9 no signal
462 Product Distribution Issue 12 0.9 0.9 no signal
463 Cerebral Ischaemia 7 0.9 0.9 no signal
464 Hydronephrosis 10 0.9 0.9 no signal
465 Fatigue 1,037 0.9 0.9 no signal
466 Drug Intolerance 128 0.9 0.9 no signal
467 Dyspnoea 752 0.9 0.9 no signal
468 Blood Calcium Decreased 15 0.9 0.9 no signal
469 Oxygen Saturation Decreased 74 0.9 0.9 no signal
470 Acne 101 0.9 0.9 no signal
471 General Physical Condition Abnormal 9 0.9 0.9 no signal
472 Subdural Haematoma 19 0.9 0.9 no signal
473 Gastrointestinal Motility Disorder 7 0.9 0.9 no signal
474 Epistaxis 98 0.9 0.9 no signal
475 Conjunctivitis 24 0.9 0.9 no signal
476 Cholangitis 8 0.9 0.9 no signal
477 Cognitive Disorder 60 0.8 0.8 no signal
478 Pelvic Fracture 10 0.8 0.8 no signal
479 Hypoxia 45 0.8 0.8 no signal
480 Diarrhoea Haemorrhagic 12 0.8 0.8 no signal
481 Pulmonary Haemorrhage 10 0.8 0.8 no signal
482 Colitis Microscopic 6 0.8 0.8 no signal
483 Deafness Unilateral 7 0.8 0.8 no signal
484 Dry Mouth 103 0.8 0.8 no signal
485 Cardiac Arrest 105 0.8 0.8 no signal
486 Hyperkeratosis 7 0.8 0.8 no signal
487 Blood Albumin Decreased 10 0.8 0.8 no signal
488 Blood Potassium Decreased 38 0.8 0.8 no signal
489 Pericarditis 21 0.8 0.8 no signal
490 Chronic Lymphocytic Leukaemia 6 0.8 0.8 no signal
491 Lower Limb Fracture 24 0.8 0.8 no signal
492 Stevens-johnson Syndrome 28 0.8 0.8 no signal
493 Illness 126 0.8 0.8 no signal
494 Gastric Ulcer Haemorrhage 7 0.8 0.8 no signal
495 Paralysis 18 0.8 0.8 no signal
496 Bone Disorder 23 0.8 0.8 no signal
497 Mitral Valve Incompetence 14 0.8 0.8 no signal
498 Musculoskeletal Discomfort 21 0.8 0.8 no signal
499 Gastrointestinal Sounds Abnormal 6 0.8 0.8 no signal
500 Cardiac Valve Disease 7 0.8 0.8 no signal
501 Hyperaesthesia 10 0.8 0.8 no signal
502 Blood Alkaline Phosphatase Increased 30 0.8 0.8 no signal
503 Productive Cough 57 0.8 0.8 no signal
504 Spinal Fracture 24 0.8 0.8 no signal
505 Dermatitis Allergic 15 0.8 0.8 no signal
506 Dyspnoea Exertional 45 0.8 0.8 no signal
507 Muscle Atrophy 15 0.8 0.8 no signal
508 Constipation 258 0.8 0.8 no signal
509 Erysipelas 6 0.8 0.8 no signal
510 Choking 23 0.8 0.8 no signal
511 Tachypnoea 16 0.8 0.8 no signal
512 Bone Pain 69 0.8 0.8 no signal
513 Coma 56 0.8 0.8 no signal
514 Head Injury 37 0.8 0.8 no signal
515 Malnutrition 13 0.8 0.8 no signal
516 Renal Failure 156 0.8 0.8 no signal
517 Photosensitivity Reaction 19 0.8 0.8 no signal
518 Immunosuppression 10 0.8 0.8 no signal
519 Inguinal Hernia 7 0.8 0.8 no signal
520 Glaucoma 22 0.8 0.8 no signal
521 Hand Fracture 8 0.7 0.7 no signal
522 Blood Lactate Dehydrogenase Increased 18 0.7 0.7 no signal
523 Epilepsy 34 0.7 0.7 no signal
524 Multiple Organ Dysfunction Syndrome 31 0.7 0.7 no signal
525 Inflammation 57 0.7 0.7 no signal
526 Skin Haemorrhage 16 0.7 0.7 no signal
527 Haemophagocytic Lymphohistiocytosis 8 0.7 0.7 no signal
528 Speech Disorder 58 0.7 0.7 no signal
529 Hiccups 9 0.7 0.7 no signal
530 Haemoglobin Abnormal 7 0.7 0.7 no signal
531 Rash Pruritic 59 0.7 0.7 no signal
532 Tuberculosis 14 0.7 0.7 no signal
533 Peripheral Swelling 167 0.7 0.7 no signal
534 Gastrointestinal Disorder 96 0.7 0.7 no signal
535 Diverticulitis 30 0.7 0.7 no signal
536 Skin Exfoliation 90 0.7 0.7 no signal
537 Wound 30 0.7 0.7 no signal
538 Appendicitis 10 0.7 0.7 no signal
539 Cardiac Failure Congestive 87 0.7 0.7 no signal
540 Lacrimation Increased 32 0.7 0.7 no signal
541 Limb Injury 29 0.7 0.7 no signal
542 Palmar-plantar Erythrodysaesthesia Syndrome 25 0.7 0.7 no signal
543 Eye Disorder 35 0.7 0.7 no signal
544 Alopecia 209 0.7 0.7 no signal
545 Blood Pressure Abnormal 21 0.7 0.7 no signal
546 Hypocalcaemia 20 0.7 0.7 no signal
547 Arteriosclerosis Coronary Artery 7 0.7 0.7 no signal
548 Skin Hyperpigmentation 9 0.7 0.7 no signal
549 Fall 349 0.7 0.7 no signal
550 Pyrexia 361 0.7 0.7 no signal
551 Full Blood Count Decreased 21 0.7 0.7 no signal
552 Breast Mass 7 0.7 0.7 no signal
553 Herpes Virus Infection 6 0.7 0.7 no signal
554 Atrioventricular Block 8 0.7 0.7 no signal
555 Nephrolithiasis 47 0.7 0.7 no signal
556 Gastritis 27 0.7 0.7 no signal
557 Herpes Zoster 59 0.7 0.7 no signal
558 Liver Function Test Abnormal 30 0.7 0.7 no signal
559 Respiration Abnormal 7 0.7 0.7 no signal
560 Intentional Dose Omission 28 0.7 0.7 no signal
561 Gingival Bleeding 14 0.7 0.7 no signal
562 Dysgeusia 76 0.7 0.7 no signal
563 Aspiration 11 0.7 0.7 no signal
564 Oedema Peripheral 124 0.7 0.7 no signal
565 Product Dose Omission Issue 288 0.7 0.7 no signal
566 Dysphonia 59 0.7 0.7 no signal
567 Cholecystitis 12 0.7 0.7 no signal
568 Covid-19 Pneumonia 12 0.7 0.7 no signal
569 Facial Pain 9 0.7 0.7 no signal
570 Gastrointestinal Infection 9 0.7 0.7 no signal
571 Toxicity To Various Agents 169 0.7 0.7 no signal
572 Rash Macular 35 0.7 0.7 no signal
573 Transient Ischaemic Attack 34 0.7 0.7 no signal
574 Salivary Hypersecretion 10 0.7 0.7 no signal
575 Hepatitis Cholestatic 6 0.7 0.7 no signal
576 Extrasystoles 7 0.7 0.7 no signal
577 Sensory Loss 8 0.7 0.7 no signal
578 Bedridden 13 0.7 0.7 no signal
579 Neuralgia 24 0.7 0.7 no signal
580 Ascites 29 0.6 0.6 no signal
581 Dysarthria 37 0.6 0.6 no signal
582 Pancreatitis 52 0.6 0.6 no signal
583 Iron Deficiency Anaemia 9 0.6 0.6 no signal
584 Intestinal Perforation 11 0.6 0.6 no signal
585 Asphyxia 8 0.6 0.6 no signal
586 Ileus 12 0.6 0.6 no signal
587 Orthostatic Hypotension 17 0.6 0.6 no signal
588 Dermatitis Bullous 7 0.6 0.6 no signal
589 Status Epilepticus 11 0.6 0.6 no signal
590 Ovarian Cancer 9 0.6 0.6 no signal
591 Progressive Multifocal Leukoencephalopathy 8 0.6 0.6 no signal
592 Blister 54 0.6 0.6 no signal
593 Jaundice 26 0.6 0.6 no signal
594 Eosinophil Count Increased 8 0.6 0.6 no signal
595 Visual Impairment 118 0.6 0.6 no signal
596 Colitis 36 0.6 0.6 no signal
597 Skin Lesion 26 0.6 0.6 no signal
598 Uterine Leiomyoma 7 0.6 0.6 no signal
599 Localised Infection 23 0.6 0.6 no signal
600 Upper Limb Fracture 19 0.6 0.6 no signal
601 Vomiting 444 0.6 0.6 no signal
602 Acute Myocardial Infarction 28 0.6 0.6 no signal
603 Haematemesis 24 0.6 0.6 no signal
604 Hernia 18 0.6 0.6 no signal
605 Oral Discomfort 13 0.6 0.6 no signal
606 Aphonia 13 0.6 0.6 no signal
607 Parosmia 7 0.6 0.6 no signal
608 Troponin Increased 7 0.6 0.6 no signal
609 Diplopia 24 0.6 0.6 no signal
610 Adrenal Insufficiency 11 0.6 0.6 no signal
611 Flatulence 52 0.6 0.6 no signal
612 Off Label Use 797 0.6 0.6 no signal
613 Lipase Increased 7 0.6 0.6 no signal
614 Myocardial Infarction 161 0.6 0.6 no signal
615 Neutropenia 124 0.6 0.6 no signal
616 Immune System Disorder 12 0.6 0.6 no signal
617 Nausea 717 0.6 0.6 no signal
618 Heart Rate Increased 90 0.6 0.6 no signal
619 Nocturia 11 0.6 0.6 no signal
620 Hypoacusis 39 0.6 0.6 no signal
621 Lymphoma 14 0.6 0.6 no signal
622 Therapy Cessation 46 0.6 0.6 no signal
623 Gastrooesophageal Reflux Disease 72 0.6 0.6 no signal
624 Muscular Weakness 102 0.6 0.6 no signal
625 Oropharyngeal Discomfort 8 0.6 0.6 no signal
626 Infection 129 0.6 0.6 no signal
627 Colitis Ischaemic 6 0.6 0.6 no signal
628 Multiple Allergies 7 0.6 0.6 no signal
629 Dysstasia 26 0.6 0.6 no signal
630 Furuncle 7 0.6 0.6 no signal
631 Eye Discharge 9 0.6 0.6 no signal
632 Syncope 88 0.6 0.6 no signal
633 Atrial Flutter 7 0.6 0.6 no signal
634 Gait Disturbance 167 0.6 0.6 no signal
635 Blood Thyroid Stimulating Hormone Increased 8 0.6 0.6 no signal
636 Weight Fluctuation 9 0.6 0.6 no signal
637 Shock Haemorrhagic 7 0.6 0.6 no signal
638 Intestinal Obstruction 32 0.6 0.6 no signal
639 Spinal Pain 10 0.6 0.6 no signal
640 Rash Erythematous 40 0.6 0.6 no signal
641 Blindness Unilateral 12 0.6 0.6 no signal
642 Intentional Product Misuse 74 0.6 0.6 no signal
643 Incontinence 9 0.6 0.6 no signal
644 Laboratory Test Abnormal 25 0.6 0.6 no signal
645 Posterior Reversible Encephalopathy Syndrome 8 0.6 0.6 no signal
646 Delirium 29 0.6 0.6 no signal
647 Cholestasis 16 0.6 0.6 no signal
648 Septic Shock 36 0.5 0.5 no signal
649 Clostridium Difficile Infection 18 0.5 0.5 no signal
650 Product Dose Omission 55 0.5 0.5 no signal
651 Pruritus 313 0.5 0.5 no signal
652 Loss Of Personal Independence In Daily Activities 39 0.5 0.5 no signal
653 Adverse Drug Reaction 73 0.5 0.5 no signal
654 Kidney Infection 16 0.5 0.5 no signal
655 Small Intestinal Obstruction 10 0.5 0.5 no signal
656 Chest Discomfort 83 0.5 0.5 no signal
657 Amnesia 53 0.5 0.5 no signal
658 Urinary Incontinence 24 0.5 0.5 no signal
659 Secretion Discharge 10 0.5 0.5 no signal
660 Chest Pain 150 0.5 0.5 no signal
661 Limb Discomfort 25 0.5 0.5 no signal
662 Therapy Non-responder 36 0.5 0.5 no signal
663 Pancreatitis Acute 18 0.5 0.5 no signal
664 Hypersomnia 23 0.5 0.5 no signal
665 Eye Infection 9 0.5 0.5 no signal
666 Hyperkalaemia 28 0.5 0.5 no signal
667 Haematocrit Decreased 16 0.5 0.5 no signal
668 Memory Impairment 110 0.5 0.5 no signal
669 Urinary Tract Infection 136 0.5 0.5 no signal
670 Vision Blurred 109 0.5 0.5 no signal
671 Head Discomfort 14 0.5 0.5 no signal
672 Impaired Healing 26 0.5 0.5 no signal
673 Hypoaesthesia 118 0.5 0.5 no signal
674 Product Use Issue 147 0.5 0.5 no signal
675 Sepsis 87 0.5 0.5 no signal
676 Rib Fracture 16 0.5 0.5 no signal
677 Discomfort 47 0.5 0.5 no signal
678 Concussion 6 0.5 0.5 no signal
679 Folliculitis 8 0.5 0.5 no signal
680 Osteomyelitis 14 0.5 0.5 no signal
681 Cellulitis 39 0.5 0.5 no signal
682 Tendonitis 12 0.5 0.5 no signal
683 Oral Herpes 15 0.5 0.5 no signal
684 Acute Myeloid Leukaemia 12 0.5 0.5 no signal
685 Melaena 17 0.5 0.5 no signal
686 Acute Kidney Injury 117 0.5 0.5 no signal
687 Renal Injury 23 0.5 0.5 no signal
688 Hypotension 153 0.5 0.5 no signal
689 Electrocardiogram Abnormal 6 0.5 0.5 no signal
690 Glossodynia 17 0.5 0.5 no signal
691 Depressed Level Of Consciousness 30 0.5 0.5 no signal
692 Joint Dislocation 8 0.5 0.5 no signal
693 Agranulocytosis 14 0.5 0.5 no signal
694 Gastroenteritis 11 0.5 0.5 no signal
695 Bacterial Infection 14 0.5 0.5 no signal
696 Wrist Fracture 9 0.5 0.5 no signal
697 Loss Of Consciousness 96 0.5 0.5 no signal
698 Blood Disorder 6 0.5 0.5 no signal
699 Flank Pain 7 0.5 0.5 no signal
700 Heart Rate Irregular 17 0.5 0.5 no signal
701 Malignant Melanoma 10 0.5 0.5 no signal
702 Rhinorrhoea 48 0.5 0.5 no signal
703 Quality Of Life Decreased 10 0.5 0.5 no signal
704 Dyspepsia 73 0.5 0.5 no signal
705 Haematochezia 41 0.5 0.5 no signal
706 Tachycardia 66 0.5 0.5 no signal
707 Leukaemia 7 0.5 0.5 no signal
708 Eye Inflammation 7 0.5 0.5 no signal
709 Mental Impairment 18 0.5 0.5 no signal
710 Uveitis 10 0.5 0.5 no signal
711 Blood Urine Present 14 0.5 0.5 no signal
712 Neck Pain 41 0.5 0.5 no signal
713 Abnormal Faeces 6 0.5 0.5 no signal
714 Cholelithiasis 24 0.5 0.5 no signal
715 Back Pain 170 0.5 0.5 no signal
716 Pharyngeal Swelling 7 0.5 0.5 no signal
717 Dizziness Postural 7 0.5 0.5 no signal
718 Palpitations 85 0.5 0.5 no signal
719 Hypothyroidism 23 0.5 0.5 no signal
720 Hepatic Enzyme Increased 49 0.5 0.5 no signal
721 Vitreous Floaters 7 0.5 0.5 no signal
722 Drug Interaction 114 0.5 0.5 no signal
723 Vitamin D Deficiency 7 0.5 0.5 no signal
724 Pulmonary Hypertension 15 0.5 0.5 no signal
725 Movement Disorder 23 0.5 0.5 no signal
726 Blood Urea Increased 12 0.5 0.5 no signal
727 Upper Gastrointestinal Haemorrhage 12 0.5 0.5 no signal
728 Face Oedema 12 0.5 0.5 no signal
729 Swelling Face 46 0.5 0.5 no signal
730 Frequent Bowel Movements 19 0.5 0.5 no signal
731 Basal Cell Carcinoma 11 0.5 0.5 no signal
732 Osteoporosis 29 0.5 0.5 no signal
733 Hemiparesis 12 0.5 0.5 no signal
734 Covid-19 124 0.5 0.5 no signal
735 Myalgia 119 0.5 0.5 no signal
736 Rhabdomyolysis 29 0.5 0.5 no signal
737 Pollakiuria 29 0.5 0.5 no signal
738 Hiatus Hernia 9 0.5 0.5 no signal
739 Oral Candidiasis 9 0.5 0.5 no signal
740 Myelodysplastic Syndrome 10 0.5 0.5 no signal
741 Cardiac Murmur 6 0.5 0.5 no signal
742 Cardio-respiratory Arrest 29 0.5 0.5 no signal
743 Hypokinesia 10 0.5 0.5 no signal
744 Blood Calcium Increased 6 0.4 0.4 no signal
745 Respiratory Arrest 19 0.4 0.4 no signal
746 Feeling Cold 19 0.4 0.4 no signal
747 Haemoglobin Decreased 70 0.4 0.4 no signal
748 Malaise 297 0.4 0.4 no signal
749 Eye Haemorrhage 9 0.4 0.4 no signal
750 Petechiae 7 0.4 0.4 no signal
751 Accident 8 0.4 0.4 no signal
752 Tooth Disorder 15 0.4 0.4 no signal
753 Nervous System Disorder 21 0.4 0.4 no signal
754 Abdominal Discomfort 112 0.4 0.4 no signal
755 Haemorrhoids 13 0.4 0.4 no signal
756 Cardiovascular Disorder 17 0.4 0.4 no signal
757 Febrile Neutropenia 44 0.4 0.4 no signal
758 Drug Level Increased 11 0.4 0.4 no signal
759 Urinary Retention 22 0.4 0.4 no signal
760 Candida Infection 11 0.4 0.4 no signal
761 Balance Disorder 57 0.4 0.4 no signal
762 Retching 14 0.4 0.4 no signal
763 Erythema 135 0.4 0.4 no signal
764 Nerve Compression 6 0.4 0.4 no signal
765 Thyroid Disorder 10 0.4 0.4 no signal
766 Hypomagnesaemia 9 0.4 0.4 no signal
767 Pain 398 0.4 0.4 no signal
768 Product Packaging Issue 6 0.4 0.4 no signal
769 Haematuria 22 0.4 0.4 no signal
770 Dizziness 319 0.4 0.4 no signal
771 Drug Effect Less Than Expected 9 0.4 0.4 no signal
772 Respiratory Disorder 19 0.4 0.4 no signal
773 Hypokalaemia 29 0.4 0.4 no signal
774 Eructation 12 0.4 0.4 no signal
775 Gastrointestinal Haemorrhage 53 0.4 0.4 no signal
776 Blood Bilirubin Increased 17 0.4 0.4 no signal
777 Pain In Extremity 185 0.4 0.4 no signal
778 Therapy Interrupted 43 0.4 0.4 no signal
779 Hyperthyroidism 9 0.4 0.4 no signal
780 Blood Potassium Increased 10 0.4 0.4 no signal
781 Swelling 57 0.4 0.4 no signal
782 Hepatomegaly 6 0.4 0.4 no signal
783 Cytomegalovirus Infection 10 0.4 0.4 no signal
784 Eyelid Ptosis 6 0.4 0.4 no signal
785 Temperature Intolerance 6 0.4 0.4 no signal
786 Ataxia 7 0.4 0.4 no signal
787 Circulatory Collapse 10 0.4 0.4 no signal
788 Urticaria 97 0.4 0.4 no signal
789 Ill-defined Disorder 35 0.4 0.4 no signal
790 Musculoskeletal Disorder 11 0.4 0.4 no signal
791 Blood Pressure Decreased 38 0.4 0.4 no signal
792 Treatment Failure 47 0.4 0.4 no signal
793 Rash Generalised 15 0.4 0.4 no signal
794 Blood Test Abnormal 8 0.4 0.4 no signal
795 Musculoskeletal Pain 30 0.4 0.4 no signal
796 Tinnitus 26 0.4 0.4 no signal
797 Cystitis 18 0.4 0.4 no signal
798 Muscle Twitching 13 0.4 0.4 no signal
799 Hypertension 119 0.4 0.4 no signal
800 Drug Ineffective 738 0.4 0.4 no signal
801 Gallbladder Disorder 10 0.4 0.4 no signal
802 Intentional Product Use Issue 49 0.4 0.4 no signal
803 Chronic Obstructive Pulmonary Disease 29 0.4 0.4 no signal
804 Confusional State 90 0.4 0.4 no signal
805 Gastroenteritis Viral 10 0.4 0.4 no signal
806 Back Disorder 9 0.4 0.4 no signal
807 Gastrointestinal Pain 6 0.4 0.4 no signal
808 Gastric Cancer 14 0.4 0.4 no signal
809 Influenza 61 0.4 0.4 no signal
810 Haemorrhage 57 0.4 0.4 no signal
811 Staphylococcal Infection 18 0.4 0.4 no signal
812 Urosepsis 5 0.4 0.4 no signal
813 Viral Infection 18 0.4 0.4 no signal
814 Contusion 52 0.4 0.4 no signal
815 Blood Pressure Fluctuation 13 0.4 0.4 no signal
816 Oropharyngeal Pain 50 0.4 0.4 no signal
817 Body Temperature Increased 11 0.4 0.4 no signal
818 Ocular Hyperaemia 25 0.4 0.4 no signal
819 Haemorrhage Intracranial 8 0.4 0.4 no signal
820 Hypoaesthesia Oral 8 0.3 0.3 no signal
821 Peritonitis 11 0.3 0.3 no signal
822 Abdominal Distension 55 0.3 0.3 no signal
823 Insomnia 141 0.3 0.3 no signal
824 Foot Fracture 10 0.3 0.3 no signal
825 Shock 12 0.3 0.3 no signal
826 Eye Pain 29 0.3 0.3 no signal
827 Osteopenia 8 0.3 0.3 no signal
828 Autoimmune Disorder 5 0.3 0.3 no signal
829 Angina Pectoris 15 0.3 0.3 no signal
830 Condition Aggravated 157 0.3 0.3 no signal
831 White Blood Cell Count Increased 20 0.3 0.3 no signal
832 Product Use Complaint 8 0.3 0.3 no signal
833 Ankle Fracture 8 0.3 0.3 no signal
834 Abdominal Pain Upper 106 0.3 0.3 no signal
835 Sleep Disorder 36 0.3 0.3 no signal
836 Heart Rate Decreased 18 0.3 0.3 no signal
837 Bacteraemia 6 0.3 0.3 no signal
838 Inflammatory Bowel Disease 5 0.3 0.3 no signal
839 Peripheral Coldness 7 0.3 0.3 no signal
840 Ligament Sprain 5 0.3 0.3 no signal
841 Mental Disorder 22 0.3 0.3 no signal
842 Abscess 8 0.3 0.3 no signal
843 Gout 9 0.3 0.3 no signal
844 Stress 36 0.3 0.3 no signal
845 Toothache 9 0.3 0.3 no signal
846 Seasonal Allergy 7 0.3 0.3 no signal
847 Osteoarthritis 21 0.3 0.3 no signal
848 Headache 309 0.3 0.3 no signal
849 Vertigo 30 0.3 0.3 no signal
850 Bronchospasm 7 0.3 0.3 no signal
851 Generalised Tonic-clonic Seizure 8 0.3 0.3 no signal
852 Mobility Decreased 35 0.3 0.3 no signal
853 Dysuria 18 0.3 0.3 no signal
854 Impaired Quality Of Life 7 0.3 0.3 no signal
855 Neutrophil Count Increased 5 0.3 0.3 no signal
856 Blood Glucose Abnormal 9 0.3 0.3 no signal
857 Product Dose Omission In Error 13 0.3 0.3 no signal
858 Scratch 5 0.3 0.3 no signal
859 Paraesthesia 76 0.3 0.3 no signal
860 Coagulopathy 8 0.3 0.3 no signal
861 Skin Irritation 22 0.3 0.3 no signal
862 Increased Appetite 9 0.3 0.3 no signal
863 Eczema 24 0.3 0.3 no signal
864 Incorrect Route Of Product Administration 8 0.3 0.3 no signal
865 Wheezing 28 0.3 0.3 no signal
866 Fluid Retention 24 0.3 0.3 no signal
867 Lethargy 27 0.3 0.3 no signal
868 Breast Pain 5 0.3 0.3 no signal
869 Musculoskeletal Stiffness 41 0.3 0.3 no signal
870 C-reactive Protein Increased 17 0.3 0.3 no signal
871 Poor Quality Sleep 10 0.3 0.3 no signal
872 Night Sweats 15 0.3 0.3 no signal
873 Skin Cancer 10 0.3 0.3 no signal
874 Blood Pressure Increased 71 0.3 0.3 no signal
875 Ear Pain 9 0.3 0.3 no signal
876 Faeces Discoloured 10 0.3 0.3 no signal
877 Laryngitis 5 0.3 0.3 no signal
878 Neurotoxicity 8 0.3 0.3 no signal
879 Joint Swelling 55 0.3 0.3 no signal
880 Infusion Related Reaction 30 0.3 0.3 no signal
881 Sinus Disorder 9 0.3 0.3 no signal
882 Disorientation 18 0.3 0.3 no signal
883 Fungal Infection 15 0.3 0.3 no signal
884 Sars-cov-2 Test Positive 6 0.3 0.3 no signal
885 Sneezing 10 0.3 0.3 no signal
886 Product Use In Unapproved Indication 109 0.3 0.3 no signal
887 Pain Of Skin 12 0.3 0.3 no signal
888 Arthralgia 184 0.3 0.3 no signal
889 Restless Legs Syndrome 8 0.3 0.3 no signal
890 Restlessness 16 0.3 0.3 no signal
891 Eye Swelling 16 0.3 0.3 no signal
892 Diabetes Mellitus 33 0.3 0.3 no signal
893 Hepatic Cirrhosis 8 0.3 0.3 no signal
894 Coordination Abnormal 6 0.3 0.3 no signal
895 Madarosis 5 0.3 0.3 no signal
896 Lip Swelling 14 0.3 0.3 no signal
897 Chronic Kidney Disease 32 0.3 0.3 no signal
898 Post Procedural Complication 8 0.3 0.3 no signal
899 Blood Glucose Decreased 20 0.3 0.3 no signal
900 Anosmia 6 0.3 0.3 no signal
901 Thyroid Cancer 5 0.3 0.3 no signal
902 Intervertebral Disc Protrusion 9 0.3 0.3 no signal
903 Decreased Immune Responsiveness 4 0.3 0.3 no signal
904 Encephalopathy 10 0.3 0.3 no signal
905 Scar 7 0.3 0.3 no signal
906 Road Traffic Accident 17 0.3 0.3 no signal
907 Bronchitis 30 0.3 0.3 no signal
908 Throat Irritation 18 0.3 0.3 no signal
909 Depression 92 0.3 0.3 no signal
910 Cyst 5 0.3 0.3 no signal
911 Rash Papular 9 0.3 0.3 no signal
912 Abdominal Pain 93 0.3 0.3 no signal
913 Hypersensitivity 74 0.3 0.3 no signal
914 Hypotonia 4 0.3 0.3 no signal
915 Hair Colour Changes 5 0.3 0.3 no signal
916 Mental Status Changes 11 0.3 0.3 no signal
917 Rectal Haemorrhage 17 0.3 0.3 no signal
918 Sluggishness 4 0.3 0.3 no signal
919 Thirst 7 0.3 0.3 no signal
920 Drug Level Decreased 4 0.3 0.3 no signal
921 Feeling Hot 24 0.3 0.3 no signal
922 Adverse Event 36 0.3 0.3 no signal
923 Nasopharyngitis 72 0.3 0.3 no signal
924 Intraocular Pressure Increased 5 0.3 0.3 no signal
925 Device Related Infection 6 0.3 0.3 no signal
926 Respiratory Tract Infection 10 0.3 0.3 no signal
927 Haematoma 10 0.3 0.3 no signal
928 Chills 45 0.3 0.3 no signal
929 Somnolence 77 0.3 0.2 no signal
930 Complication Associated With Device 5 0.2 0.2 no signal
931 Respiratory Tract Congestion 6 0.2 0.2 no signal
932 Hepatic Steatosis 7 0.2 0.2 no signal
933 Sleep Disorder Due To A General Medical Condition 6 0.2 0.2 no signal
934 Hepatic Cancer 9 0.2 0.2 no signal
935 Treatment Noncompliance 20 0.2 0.2 no signal
936 Acute Hepatic Failure 5 0.2 0.2 no signal
937 Product Packaging Quantity Issue 4 0.2 0.2 no signal
938 Sleep Apnoea Syndrome 7 0.2 0.2 no signal
939 Bipolar Disorder 4 0.2 0.2 no signal
940 Eye Pruritus 12 0.2 0.2 no signal
941 Coronary Artery Occlusion 5 0.2 0.2 no signal
942 Multiple Fractures 6 0.2 0.2 no signal
943 Therapeutic Product Effect Decreased 16 0.2 0.2 no signal
944 Coronary Artery Disease 11 0.2 0.2 no signal
945 Eye Irritation 20 0.2 0.2 no signal
946 Chromaturia 8 0.2 0.2 no signal
947 Anaphylactic Reaction 19 0.2 0.2 no signal
948 Drug Hypersensitivity 67 0.2 0.2 no signal
949 Pancreatic Carcinoma 10 0.2 0.2 no signal
950 Eosinophilia 6 0.2 0.2 no signal
951 Depressed Mood 18 0.2 0.2 no signal
952 Feeling Abnormal 82 0.2 0.2 no signal
953 Cold Sweat 6 0.2 0.2 no signal
954 Psychotic Disorder 10 0.2 0.2 no signal
955 Colitis Ulcerative 15 0.2 0.2 no signal
956 Therapeutic Response Unexpected 15 0.2 0.2 no signal
957 Oesophageal Carcinoma 10 0.2 0.2 no signal
958 Pallor 9 0.2 0.2 no signal
959 Pelvic Pain 6 0.2 0.2 no signal
960 Burning Sensation 23 0.2 0.2 no signal
961 No Adverse Event 58 0.2 0.2 no signal
962 Nasal Congestion 19 0.2 0.2 no signal
963 Skin Burning Sensation 23 0.2 0.2 no signal
964 Product Dispensing Error 7 0.2 0.2 no signal
965 Personality Change 3 0.2 0.2 no signal
966 Hallucination 24 0.2 0.2 no signal
967 Breast Cancer 30 0.2 0.2 no signal
968 Gastric Disorder 11 0.2 0.2 no signal
969 Drug Reaction With Eosinophilia And Systemic Symptoms 8 0.2 0.2 no signal
970 Genital Haemorrhage 4 0.2 0.2 no signal
971 Lower Respiratory Tract Infection 14 0.2 0.2 no signal
972 Blood Pressure Systolic Increased 6 0.2 0.2 no signal
973 Arthropathy 17 0.2 0.2 no signal
974 Arthritis 24 0.2 0.2 no signal
975 Product Taste Abnormal 4 0.2 0.2 no signal
976 Migraine 28 0.2 0.2 no signal
977 Weight Increased 65 0.2 0.2 no signal
978 Prostatic Specific Antigen Increased 4 0.2 0.2 no signal
979 Swollen Tongue 9 0.2 0.2 no signal
980 Anxiety 82 0.2 0.2 no signal
981 Tremor 47 0.2 0.2 no signal
982 Sinusitis 29 0.2 0.2 no signal
983 Plasma Cell Myeloma 11 0.2 0.2 no signal
984 Asthma 31 0.2 0.2 no signal
985 Abdominal Pain Lower 7 0.2 0.2 no signal
986 Extra Dose Administered 11 0.2 0.2 no signal
987 Hyperglycaemia 10 0.2 0.2 no signal
988 Pulmonary Arterial Hypertension 4 0.2 0.2 no signal
989 Visual Acuity Reduced 9 0.2 0.2 no signal
990 Bone Loss 4 0.2 0.2 no signal
991 Inappropriate Schedule Of Product Administration 46 0.2 0.2 no signal
992 Agitation 19 0.2 0.2 no signal
993 Systemic Lupus Erythematosus 9 0.2 0.2 no signal
994 Drug Ineffective For Unapproved Indication 14 0.2 0.2 no signal
995 Nervousness 13 0.2 0.2 no signal
996 Bradycardia 13 0.2 0.2 no signal
997 Glycosylated Haemoglobin Increased 6 0.2 0.2 no signal
998 Poisoning 3 0.2 0.2 no signal
999 Medication Error 13 0.2 0.2 no signal
1000 Hypoglycaemia 11 0.1 0.1 no signal
1001 Therapeutic Product Effect Incomplete 16 0.1 0.1 no signal
1002 Overdose 49 0.1 0.1 no signal
1003 Akathisia 3 0.1 0.1 no signal
1004 Upper Respiratory Tract Infection 10 0.1 0.1 no signal
1005 Hospitalisation 33 0.1 0.1 no signal
1006 Blood Glucose Increased 40 0.1 0.1 no signal
1007 Vaginal Haemorrhage 9 0.1 0.1 no signal
1008 Osteonecrosis 7 0.1 0.1 no signal
1009 Drug Dose Omission 35 0.1 0.1 no signal
1010 Type 2 Diabetes Mellitus 7 0.1 0.1 no signal
1011 Meningioma 3 0.1 0.1 no signal
1012 Disturbance In Attention 11 0.1 0.1 no signal
1013 Emotional Disorder 6 0.1 0.1 no signal
1014 Maternal Exposure During Pregnancy 17 0.1 0.1 no signal
1015 Prostate Cancer 15 0.1 0.1 no signal
1016 Wrong Technique In Product Usage Process 37 0.1 0.1 no signal
1017 Dyskinesia 7 0.1 0.1 no signal
1018 Blood Cholesterol Increased 8 0.1 0.1 no signal
1019 Drug Effective For Unapproved Indication 5 0.1 0.1 no signal
1020 Crying 6 0.1 0.1 no signal
1021 Accidental Overdose 6 0.1 0.1 no signal
1022 Hyperhidrosis 21 0.1 0.1 no signal
1023 Exposure During Pregnancy 10 0.1 0.1 no signal
1024 Angioedema 7 0.1 0.1 no signal
1025 Hot Flush 11 0.1 0.1 no signal
1026 Unevaluable Event 11 0.1 0.1 no signal
1027 Irritability 8 0.1 0.1 no signal
1028 Therapeutic Response Decreased 8 0.1 0.1 no signal
1029 Flushing 13 0.1 0.1 no signal
1030 Rheumatoid Arthritis 14 0.1 0.1 no signal
1031 Injury 8 0.1 0.1 no signal
1032 Breast Cancer Female 3 0.1 0.1 no signal
1033 Renal Cancer 5 0.1 0.1 no signal
1034 Dermatitis Atopic 5 0.1 0.1 no signal
1035 Influenza Like Illness 8 0.1 0.1 no signal
1036 Incorrect Dose Administered 19 0.1 0.1 no signal
1037 Bladder Cancer 5 0.1 0.1 no signal
1038 Product Storage Error 7 0.1 0.1 no signal
1039 Emotional Distress 8 0.0 0.0 no signal
1040 Psoriasis 8 0.0 0.0 no signal
1041 Product Quality Issue 8 0.0 0.0 no signal