Reaction

Gene Mutation reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,961 reports · 122 co-occurring drugs

As of the last recalculation, Gene Mutation appears in 1,961 FAERS reports alongside 122 co-occurring drug terms. The strongest observed disproportionality signal is IMATINIB (PRR 62.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Imatinib	98	62.0	62.4
Gefitinib	45	54.1	54.4
Nevirapine	43	51.7	51.9
Lamivudine Oral	109	48.4	48.6
Lamivudine	110	40.0	40.1
Abacavir Sulfate	36	39.9	40.1
Panitumumab	54	37.6	37.7
Efavirenz	34	32.9	33.0
Darunavir	44	31.6	31.7
Ritonavir 100 Mg	38	27.5	27.6
Atovaquone	20	26.6	26.7
Zidovudine	33	26.6	26.7
Pemetrexed	52	26.4	26.5
Blinatumomab	25	25.7	25.8
Erlotinib	23	25.5	25.5
Magnesium Sulfate In Water For	30	25.3	25.4
Tenofovir Disoproxil Fumarate Tablets	20	24.8	24.9
Magnesium Sulfate Heptahydrate	30	24.8	24.9
Magnesium Sulfate	30	24.8	24.8
Valganciclovir Hydrochloride Powder,	28	24.7	24.8
Ifosfamide	48	24.3	24.3
Dasatinib	78	23.2	23.2
Nilotinib	58	21.5	21.5
Osimertinib	62	21.2	21.2
Labetalol	25	20.2	20.2
Erlotinib Hydrochloride	23	19.7	19.8
Fludarabine Phosphate	70	19.6	19.6
Vincristine Sulfate	50	18.6	18.6
Valganciclovir	30	17.1	17.2
Valganciclovir Hydrochloride	30	17.1	17.2
Clobazam	37	16.4	16.4
Anastrozole Tablets	32	16.1	16.1
Pemetrexed Disodium	56	16.0	16.1
Doxorubicin Hydrochloride	48	16.0	16.0
Alpelisib	13	15.9	16.0
Valproic Acid	45	15.5	15.5
Bosutinib	13	15.5	15.5
Raltegravir	23	14.9	15.0
Canakinumab	15	14.8	14.8
Doxorubicin	117	14.8	14.8
Ritonavir	39	14.4	14.5
Cytarabine	77	14.1	14.1
Midazolam	33	14.1	14.1
Midazolam Hydrochloride	35	14.0	14.0
Filgrastim	48	13.9	13.9
Fulvestrant	42	13.8	13.8
Human Immunoglobulin G	26	13.5	13.6
Etoposide	87	13.1	13.1
Azacitidine For	22	13.0	13.0
Ganciclovir	12	12.5	12.5
Eculizumab	62	12.5	12.5
Tenofovir Disoproxil Fumarate	38	12.4	12.4
Temozolomide	24	12.2	12.2
Lacosamide	42	12.2	12.2
Ganciclovir Sodium	12	12.1	12.1
Cyclophosphamide Injection, Solution	180	11.8	11.8
Cyclophosphamide	180	11.8	11.8
Cyclophosphamide For Injection	180	11.8	11.8
Crizotinib	14	11.8	11.8
Ribociclib	34	11.6	11.6
Oxcarbazepine	35	11.6	11.6
Regorafenib	12	11.0	11.0
Propofol	37	10.9	10.9
Everolimus Tablets	17	10.8	10.9
Melphalan	21	9.9	9.9
Atezolizumab	35	9.7	9.7
Anastrozole	33	9.7	9.7
Letrozole Tablets	42	9.4	9.5
Sorafenib	18	9.3	9.3
Hydroxyurea	18	9.1	9.1
Letrozole	51	9.0	9.0
Melphalan Hydrochloride	21	9.0	9.0
Oxaliplatin	61	9.0	9.0
Busulfan	13	8.8	8.8
Gemcitabine	32	8.7	8.8
Leucovorin Calcium	15	8.4	8.4
Azacitidine	23	8.3	8.3
Entecavir	9	8.2	8.2
Fluorouracil Cream, 0.5%	56	8.0	8.0
Bevacizumab	89	7.9	7.9
Goserelin	10	7.9	7.9
Fluorouracil	56	7.9	7.9
Cisplatin	56	7.8	7.8
Cladribine	7	7.8	7.8
Phenytoin	15	7.7	7.7
Olaparib	15	7.7	7.7
Daspone	7	7.7	7.7
Dapsone Gel, 5%	7	7.6	7.7
Exemestane	15	7.5	7.5
Mycophenilic Acid	14	7.2	7.2
Ceftriaxone	22	7.2	7.2
Lopinavir And Ritonavir	9	7.1	7.1
Dapsone	7	7.0	7.0
Carboplatin	78	6.7	6.8
Gemcitabine Hydrochloride	33	6.7	6.7
Ceftriaxone Sodium	23	6.4	6.4
Romiplostim	9	6.4	6.4
Rifampicin	6	6.3	6.3
Micafungin Sodium	5	6.3	6.3
Bendamustine Hcl	9	6.2	6.2
Posaconazole Delayed-Release	6	5.8	5.8
Paclitaxel	53	5.8	5.8
Cetuximab	17	5.8	5.8
Imatinib Mesylate	15	5.7	5.7
Paclitaxel (Aibumin-Bound)	41	5.4	5.4
Asfotase Alfa	5	5.3	5.3
Docetaxel Anhydrous	33	5.3	5.3
Docetaxel	33	5.3	5.3
Atazanavir	7	5.2	5.2
Trastuzumab	32	5.0	5.0
Levetiracetam In Sodium Chloride	36	5.0	5.0
Levetiracetam Oral	36	5.0	5.0
Levetiracetam Injection	36	5.0	5.0
Capecitabine	40	4.7	4.7
Palbociclib	41	4.6	4.6
Venetoclax	26	4.5	4.5
Carfilzomib	12	4.5	4.5
Ravulizumab	5	3.9	3.9
Eltrombopag Olamine	7	3.2	3.2
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	5	2.9	2.9
Vigabatrin	4	2.9	2.9
Emtricitabine And Tenofovir Alafenamide	3	2.8	2.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.