OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Pegaspargase

1,007 flagged reaction(s) · 44,116 total co-reports · max PRR 7,362.4
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Antithrombin Iii 13 7,362.4 7,370.3 signal
2 Human Bocavirus Infection 132 4,004.8 4,048.7 signal
3 Lymphoid Tissue Hypoplasia 78 1,920.6 1,933.0 signal
4 Thymus Hypoplasia 84 1,659.5 1,671.0 signal
5 Perineal Necrosis 19 1,537.2 1,539.6 signal
6 Cystitis Bacterial 106 783.0 789.9 signal
7 Hypofibrinogenaemia 300 775.8 795.4 signal
8 Norovirus Test Positive 99 761.1 767.3 signal
9 Enzyme Activity Decreased 6 728.2 728.5 signal
10 Mycobacterium Chelonae Infection 177 546.8 554.8 signal
11 Antithrombin Iii Decreased 56 457.4 459.5 signal
12 Abscess Bacterial 70 420.3 422.7 signal
13 Secondary Immunodeficiency 229 409.6 417.4 signal
14 Fibrinous Bronchitis 14 403.2 403.6 signal
15 Acral Lentiginous Melanoma 8 399.8 400.0 signal
16 Antithrombin Iii Deficiency 15 354.0 354.4 signal
17 Febrile Bone Marrow Aplasia 677 332.9 352.5 signal
18 Multiple Lentigines Syndrome 6 318.6 318.7 signal
19 Lewis-sumner Syndrome 8 308.9 309.1 signal
20 Corona Virus Infection 64 297.1 298.7 signal
21 Periorbital Infection 11 263.2 263.5 signal
22 Bacillus Test Positive 13 256.8 257.1 signal
23 Pseudomonal Sepsis 214 238.4 242.7 signal
24 Anorectal Cellulitis 7 224.4 224.5 signal
25 Chemotherapeutic Drug Level Increased 17 188.8 189.0 signal
26 Perineal Infection 19 180.3 180.6 signal
27 Bacillus Bacteraemia 10 171.6 171.8 signal
28 Parainfluenzae Virus Infection 139 170.0 172.0 signal
29 Disseminated Trichosporonosis 6 169.9 170.0 signal
30 Stomatococcal Infection 11 169.9 170.1 signal
31 Overgrowth Fungal 9 164.4 164.5 signal
32 Disseminated Aspergillosis 40 160.7 161.2 signal
33 Enterobacter Infection 143 160.5 162.4 signal
34 Bacteroides Test Positive 5 146.5 146.5 signal
35 Blood Fibrinogen Decreased 84 139.6 140.6 signal
36 Human Herpesvirus 6 Infection 142 138.7 140.4 signal
37 Superior Sagittal Sinus Thrombosis 58 133.2 133.8 signal
38 Gallbladder Oedema 21 132.6 132.9 signal
39 Hypertriglyceridaemia 410 130.3 134.8 signal
40 Renal Replacement Therapy 9 128.5 128.6 signal
41 Encephalitis Fungal 6 124.3 124.4 signal
42 Abscess Fungal 11 123.8 123.9 signal
43 Escherichia Pyelonephritis 16 117.2 117.3 signal
44 Diffuse Alveolar Damage 72 114.6 115.3 signal
45 Pyomyositis 18 111.2 111.4 signal
46 Jaundice Hepatocellular 6 109.6 109.7 signal
47 Enterovirus Test Positive 10 104.9 105.0 signal
48 Viraemia 79 103.6 104.3 signal
49 Pseudohyponatraemia 7 98.3 98.3 signal
50 Enterococcus Test Positive 35 97.6 97.9 signal
51 Cryptococcal Fungaemia 7 94.4 94.4 signal
52 Human Metapneumovirus Test Positive 6 91.8 91.9 signal
53 Pneumatosis Intestinalis 142 90.7 91.8 signal
54 Rhinovirus Infection 185 88.2 89.5 signal
55 Lentigo 24 87.1 87.3 signal
56 Mucosal Infection 11 85.0 85.0 signal
57 Cytomegalovirus Chorioretinitis 89 83.3 83.9 signal
58 Cholangitis Infective 12 82.5 82.6 signal
59 Human Rhinovirus Test Positive 17 82.3 82.4 signal
60 Prothrombin Level Abnormal 7 80.9 81.0 signal
61 Mucocutaneous Ulceration 10 80.5 80.6 signal
62 Pseudomonas Test Positive 36 78.6 78.8 signal
63 Leukaemic Infiltration 6 77.2 77.3 signal
64 Infective Myositis 7 74.8 74.8 signal
65 Rhinocerebral Mucormycosis 14 73.4 73.5 signal
66 Encopresis 8 73.1 73.1 signal
67 Ecthyma 16 71.2 71.3 signal
68 Cerebral Venous Sinus Thrombosis 32 70.0 70.2 signal
69 Gastroenteritis Norovirus 52 69.8 70.1 signal
70 Candida Test Positive 16 68.3 68.4 signal
71 Caecitis 17 66.7 66.8 signal
72 Enterobacter Test Positive 9 65.6 65.7 signal
73 Blood Culture Positive 111 65.5 66.1 signal
74 Hyperbilirubinaemia 372 64.5 66.5 signal
75 Pseudomonal Bacteraemia 30 63.9 64.0 signal
76 Trichosporon Infection 14 63.1 63.2 signal
77 Escherichia Test Positive 42 62.4 62.6 signal
78 Blood Lactic Acid Decreased 6 61.8 61.8 signal
79 Cerebral Venous Thrombosis 63 61.6 61.9 signal
80 Congenital Aplasia 10 61.6 61.6 signal
81 Cytomegalovirus Hepatitis 12 60.5 60.6 signal
82 Zygomycosis 16 60.1 60.2 signal
83 Pancreatitis Necrotising 70 54.8 55.1 signal
84 Enterobacter Bacteraemia 9 52.9 52.9 signal
85 Gram Stain Positive 6 52.0 52.0 signal
86 Fusarium Infection 20 51.9 52.0 signal
87 Anorectal Infection 7 48.7 48.8 signal
88 Bacillus Infection 17 48.1 48.2 signal
89 Pulmonary Mucormycosis 14 48.1 48.1 signal
90 Aspergillus Infection 173 47.2 47.9 signal
91 Bronchopulmonary Aspergillosis 205 47.0 47.7 signal
92 Mucormycosis 68 46.7 47.0 signal
93 Transverse Sinus Thrombosis 14 46.6 46.7 signal
94 Venoocclusive Liver Disease 129 46.4 46.9 signal
95 Scedosporium Infection 18 45.9 46.0 signal
96 Escherichia Bacteraemia 60 45.9 46.1 signal
97 Venous Thrombosis 100 44.9 45.2 signal
98 Intracardiac Thrombus 79 44.8 45.1 signal
99 Oesophageal Candidiasis 100 44.7 45.0 signal
100 Clostridium Difficile Colitis 267 44.4 45.4 signal
101 Herpes Simplex Test Positive 5 44.2 44.3 signal
102 Cytomegalovirus Viraemia 109 44.0 44.4 signal
103 Escherichia Sepsis 70 42.7 42.9 signal
104 Febrile Neutropenia 1,584 42.2 48.4 signal
105 Cardiac Ventricular Thrombosis 30 41.9 42.0 signal
106 Cavernous Sinus Thrombosis 6 41.8 41.8 signal
107 Potentiating Drug Interaction 77 41.4 41.6 signal
108 Device Related Thrombosis 23 41.4 41.4 signal
109 Enterovirus Infection 20 41.2 41.3 signal
110 Intracranial Venous Sinus Thrombosis 25 40.6 40.7 signal
111 Lower Respiratory Tract Infection Fungal 9 40.3 40.4 signal
112 Neutropenic Colitis 47 40.2 40.4 signal
113 Steroid Diabetes 33 39.8 40.0 signal
114 Enterocolitis Infectious 21 39.8 39.8 signal
115 Enteritis 143 39.7 40.1 signal
116 Mixed Anxiety And Depressive Disorder 8 39.5 39.5 signal
117 Venoocclusive Disease 56 39.3 39.5 signal
118 Herpes Zoster Meningoencephalitis 8 39.1 39.1 signal
119 Aplasia 44 38.8 38.9 signal
120 Pancreatic Pseudocyst 17 38.5 38.5 signal
121 Liver Tenderness 6 37.3 37.4 signal
122 Clostridium Test Positive 46 37.1 37.2 signal
123 Steatohepatitis 11 35.9 36.0 signal
124 Alpha Haemolytic Streptococcal Infection 19 35.9 36.0 signal
125 Sinusitis Fungal 16 35.7 35.7 signal
126 Intussusception 19 35.1 35.2 signal
127 Klebsiella Test Positive 13 35.0 35.0 signal
128 Vascular Access Complication 16 34.7 34.8 signal
129 Tracheitis 15 34.7 34.7 signal
130 Staphylococcus Test Positive 41 33.9 34.0 signal
131 Fungaemia 30 33.7 33.7 signal
132 Otitis Media Acute 14 33.4 33.4 signal
133 Axillary Vein Thrombosis 7 33.3 33.3 signal
134 Candida Sepsis 17 33.2 33.2 signal
135 Respiratory Tract Infection Fungal 10 33.1 33.1 signal
136 Jugular Vein Thrombosis 33 32.8 32.9 signal
137 Pneumonia Necrotising 12 32.8 32.8 signal
138 Brain Midline Shift 10 32.7 32.8 signal
139 Acute Lymphocytic Leukaemia Recurrent 48 32.6 32.7 signal
140 Bacterial Infection 345 32.6 33.5 signal
141 Vulvitis 6 32.6 32.6 signal
142 Staphylococcal Sepsis 92 32.6 32.8 signal
143 Bone Marrow Infiltration 7 31.8 31.8 signal
144 Metastases To Pancreas 8 31.6 31.6 signal
145 Perirectal Abscess 20 31.4 31.5 signal
146 Cerebral Thrombosis 50 31.0 31.1 signal
147 Drug Clearance Decreased 22 30.6 30.7 signal
148 Anal Inflammation 11 30.3 30.4 signal
149 Ureaplasma Infection 7 30.3 30.4 signal
150 Stenotrophomonas Infection 23 30.1 30.1 signal
151 Pancreatitis Haemorrhagic 8 30.0 30.0 signal
152 Gastrointestinal Wall Thickening 25 29.5 29.5 signal
153 Leukoencephalopathy 62 29.0 29.2 signal
154 Streptococcus Test Positive 18 28.5 28.5 signal
155 Gastroenteritis Rotavirus 5 28.4 28.4 signal
156 Oedematous Pancreatitis 9 28.2 28.2 signal
157 Anal Ulcer 13 27.9 27.9 signal
158 Central Nervous System Leukaemia 6 27.6 27.6 signal
159 Bacterial Translocation 5 27.6 27.6 signal
160 Hypoalbuminaemia 120 27.4 27.7 signal
161 Systemic Mycosis 18 27.0 27.0 signal
162 Posterior Reversible Encephalopathy Syndrome 145 26.6 26.9 signal
163 Hepatobiliary Disease 9 24.9 25.0 signal
164 Systemic Candida 35 24.8 24.8 signal
165 Fungal Test Positive 5 24.7 24.7 signal
166 Anisocoria 5 24.5 24.5 signal
167 Streptococcal Bacteraemia 15 24.4 24.4 signal
168 Pneumonia Fungal 54 24.3 24.4 signal
169 Lipase Increased 105 24.0 24.2 signal
170 Peripheral Motor Neuropathy 19 23.8 23.8 signal
171 Chronic Hepatitis 11 23.7 23.8 signal
172 Enterobacter Sepsis 5 23.7 23.7 signal
173 Pneumatosis 6 23.5 23.6 signal
174 Cerebral Aspergillosis 8 22.7 22.7 signal
175 Mucosal Inflammation 339 22.7 23.3 signal
176 Staphylococcal Bacteraemia 56 22.5 22.6 signal
177 B Precursor Type Acute Leukaemia 5 22.4 22.4 signal
178 Minimal Residual Disease 6 22.3 22.3 signal
179 Haemorrhagic Infarction 7 22.1 22.2 signal
180 Hepatocellular Injury 173 21.2 21.5 signal
181 Cellulitis Orbital 7 20.9 20.9 signal
182 Klebsiella Bacteraemia 11 20.6 20.6 signal
183 Hypogonadism 12 20.5 20.6 signal
184 Platelet Transfusion 15 20.5 20.5 signal
185 Citrobacter Infection 5 20.4 20.4 signal
186 Histiocytosis Haematophagic 35 20.2 20.3 signal
187 Soft Tissue Necrosis 8 20.2 20.2 signal
188 Posturing 6 20.1 20.1 signal
189 Post Lumbar Puncture Syndrome 12 20.1 20.1 signal
190 Coronavirus Test Positive 12 20.1 20.1 signal
191 Central Nervous System Infection 13 19.8 19.8 signal
192 Respiratory Syncytial Virus Test Positive 8 19.8 19.8 signal
193 Gallbladder Enlargement 12 19.7 19.7 signal
194 Blood Lactic Acid Increased 59 19.6 19.7 signal
195 Feeding Intolerance 5 19.6 19.6 signal
196 Periorbital Cellulitis 6 19.5 19.5 signal
197 Septic Embolus 9 18.8 18.8 signal
198 Intracranial Hypotension 7 18.6 18.6 signal
199 Coagulopathy 177 18.5 18.8 signal
200 Klebsiella Sepsis 12 18.5 18.5 signal
201 Bacteraemia 124 18.3 18.5 signal
202 Subclavian Vein Thrombosis 12 18.3 18.3 signal
203 Hyperammonaemia 51 17.8 17.8 signal
204 Angiocentric Lymphoma 5 17.5 17.5 signal
205 Respiratory Tract Haemorrhage 6 17.5 17.5 signal
206 Pancreatitis Acute 223 17.4 17.7 signal
207 Atypical Haemolytic Uraemic Syndrome 8 17.2 17.3 signal
208 Scrotal Oedema 7 17.1 17.1 signal
209 Gastrointestinal Ulcer Haemorrhage 11 17.1 17.1 signal
210 Abdominal Compartment Syndrome 6 16.7 16.7 signal
211 Pulmonary Haemorrhage 75 16.7 16.8 signal
212 Fungal Sepsis 8 16.6 16.6 signal
213 Hyperlipasaemia 5 16.6 16.6 signal
214 Rectal Fissure 6 16.4 16.4 signal
215 Herpes Simplex 61 16.4 16.4 signal
216 Gastroenteritis Escherichia Coli 5 16.2 16.2 signal
217 Gastrointestinal Necrosis 27 16.2 16.2 signal
218 Pulse Absent 44 16.0 16.1 signal
219 Blood Immunoglobulin A Decreased 6 16.0 16.0 signal
220 Coagulation Test Abnormal 7 16.0 16.0 signal
221 Cholestasis 172 15.6 15.9 signal
222 Packed Red Blood Cell Transfusion 12 15.5 15.6 signal
223 Hepatomegaly 88 15.5 15.6 signal
224 Bacterial Sepsis 29 15.4 15.5 signal
225 Leukaemia Recurrent 15 15.4 15.4 signal
226 Soft Tissue Infection 16 15.3 15.4 signal
227 Oesophagitis Ulcerative 6 15.2 15.2 signal
228 Bilirubin Conjugated Increased 20 14.9 15.0 signal
229 Enterococcal Sepsis 7 14.9 14.9 signal
230 Hyperphosphataemia 18 14.7 14.8 signal
231 Hepatic Steatosis 157 14.7 14.8 signal
232 Escherichia Infection 69 14.7 14.7 signal
233 Dermo-hypodermitis 5 14.6 14.7 signal
234 Campylobacter Infection 7 14.6 14.6 signal
235 Streptococcal Sepsis 10 14.5 14.6 signal
236 B-cell Type Acute Leukaemia 6 14.5 14.5 signal
237 Activated Partial Thromboplastin Time Prolonged 41 14.0 14.0 signal
238 Pupil Fixed 14 13.9 13.9 signal
239 Heart Sounds Abnormal 6 13.9 13.9 signal
240 Viral Infection 265 13.8 14.1 signal
241 Pseudomonas Infection 67 13.7 13.8 signal
242 Amylase Increased 29 13.7 13.8 signal
243 Enterocolitis 45 13.7 13.7 signal
244 Hepatotoxicity 174 13.6 13.8 signal
245 Quadriparesis 13 13.6 13.6 signal
246 Pancreatitis 412 13.5 13.9 signal
247 Vocal Cord Paralysis 14 13.5 13.5 signal
248 Septic Shock 336 13.5 13.8 signal
249 Klebsiella Infection 39 13.5 13.5 signal
250 Oesophageal Stenosis 22 13.4 13.4 signal
251 Blood Bilirubin Increased 208 13.3 13.5 signal
252 Product Contamination Microbial 9 13.3 13.3 signal
253 Cytogenetic Analysis Abnormal 8 13.2 13.2 signal
254 Pneumonia Viral 24 13.1 13.1 signal
255 Hyperlipidaemia 89 12.9 13.0 signal
256 Intervertebral Discitis 14 12.8 12.8 signal
257 Marrow Hyperplasia 5 12.6 12.6 signal
258 Haemorrhagic Cerebral Infarction 5 12.3 12.3 signal
259 Continuous Haemodiafiltration 7 12.2 12.2 signal
260 Hepatitis Cholestatic 42 12.1 12.2 signal
261 Infection In An Immunocompromised Host 5 12.1 12.1 signal
262 Tonic Clonic Movements 9 12.0 12.1 signal
263 Procalcitonin Increased 8 12.0 12.0 signal
264 Bone Marrow Failure 141 11.9 12.1 signal
265 Ischaemic Cerebral Infarction 8 11.9 11.9 signal
266 Optic Nerve Disorder 11 11.9 11.9 signal
267 Enterococcal Infection 33 11.8 11.8 signal
268 Catarrh 6 11.7 11.7 signal
269 Atrial Thrombosis 14 11.7 11.7 signal
270 Acute Lymphocytic Leukaemia 19 11.6 11.6 signal
271 Myelosuppression 228 11.6 11.8 signal
272 Brain Herniation 20 11.6 11.6 signal
273 Varicella 16 11.6 11.6 signal
274 Glycosuria 9 11.5 11.5 signal
275 Oral Herpes 129 11.5 11.6 signal
276 Neurological Decompensation 15 11.4 11.5 signal
277 Metapneumovirus Infection 5 11.4 11.4 signal
278 Ureteric Obstruction 9 11.4 11.4 signal
279 Gamma-glutamyltransferase Increased 145 11.3 11.5 signal
280 Iron Overload 7 11.2 11.2 signal
281 Kidney Enlargement 7 11.1 11.1 signal
282 Haemophagocytic Lymphohistiocytosis 46 11.0 11.1 signal
283 Tumour Lysis Syndrome 55 10.9 11.0 signal
284 Meningitis Bacterial 9 10.9 10.9 signal
285 Blood Fibrinogen Increased 5 10.9 10.9 signal
286 Depersonalisation/derealisation Disorder 10 10.8 10.8 signal
287 Tachypnoea 84 10.7 10.8 signal
288 Multiple Organ Dysfunction Syndrome 172 10.7 10.8 signal
289 Disseminated Intravascular Coagulation 87 10.7 10.7 signal
290 Hypocoagulable State 6 10.6 10.6 signal
291 Neurotoxicity 106 10.6 10.7 signal
292 Hyperaemia 12 10.5 10.5 signal
293 Hepatic Cytolysis 74 10.5 10.5 signal
294 Cerebral Ischaemia 31 10.3 10.4 signal
295 Device Related Infection 92 10.3 10.4 signal
296 Hypertransaminasaemia 40 10.2 10.2 signal
297 Bacterial Test Positive 13 10.1 10.1 signal
298 Brain Death 18 10.0 10.1 signal
299 Pharyngeal Inflammation 7 10.0 10.0 signal
300 Hyperglycaemia 208 9.9 10.1 signal
301 Catheter Site Haemorrhage 14 9.9 9.9 signal
302 Fungal Infection 187 9.7 9.9 signal
303 Breakthrough Pain 13 9.7 9.7 signal
304 Ammonia Increased 28 9.5 9.5 signal
305 Respiratory Distress 151 9.5 9.6 signal
306 Pneumonia Klebsiella 10 9.5 9.5 signal
307 Cerebrospinal Fluid Leakage 10 9.4 9.4 signal
308 Hepatorenal Syndrome 9 9.2 9.2 signal
309 Candida Infection 88 9.1 9.2 signal
310 Pulseless Electrical Activity 22 9.1 9.1 signal
311 Adenovirus Infection 15 9.1 9.1 signal
312 Febrile Infection 6 9.0 9.0 signal
313 Colitis 195 9.0 9.1 signal
314 Peripheral Sensory Neuropathy 30 8.9 8.9 signal
315 Ascites 150 8.8 8.9 signal
316 Acidosis 39 8.8 8.8 signal
317 Pancytopenia 283 8.8 9.0 signal
318 Epstein-barr Virus Associated Lymphoproliferative Disorder 9 8.8 8.8 signal
319 Lip And/or Oral Cavity Cancer 7 8.7 8.7 signal
320 Pneumomediastinum 9 8.7 8.7 signal
321 Sepsis 562 8.7 9.1 signal
322 Pneumonia Legionella 8 8.7 8.7 signal
323 Lung Consolidation 14 8.6 8.6 signal
324 Hepatic Fibrosis 17 8.6 8.6 signal
325 Ileus Paralytic 22 8.6 8.6 signal
326 Embolism Venous 15 8.5 8.6 signal
327 Capillary Leak Syndrome 10 8.4 8.4 signal
328 Hypoproteinaemia 9 8.4 8.4 signal
329 Angioneurotic Oedema 13 8.3 8.3 signal
330 Malnutrition 53 8.3 8.3 signal
331 Subileus 10 8.3 8.3 signal
332 Non-alcoholic Steatohepatitis 5 8.2 8.2 signal
333 Pancreatic Cyst 9 8.2 8.2 signal
334 Cerebral Artery Occlusion 5 8.1 8.1 signal
335 Hepatosplenomegaly 12 8.0 8.1 signal
336 Encephalitis 32 8.0 8.0 signal
337 Hepatic Failure 140 8.0 8.1 signal
338 Blood Pressure Immeasurable 7 7.9 7.9 signal
339 Hyperglycaemic Hyperosmolar Nonketotic Syndrome 5 7.8 7.8 signal
340 Cytopenia 54 7.8 7.8 signal
341 Intra-abdominal Fluid Collection 8 7.8 7.8 signal
342 Respiratory Syncytial Virus Infection 39 7.8 7.8 signal
343 Coronavirus Infection 30 7.8 7.8 signal
344 Meningitis 30 7.8 7.8 signal
345 Alanine Aminotransferase Increased 274 7.7 7.9 signal
346 Cholecystitis 53 7.7 7.7 signal
347 Atelectasis 43 7.7 7.7 signal
348 Embolism 37 7.7 7.7 signal
349 Device Related Sepsis 9 7.7 7.7 signal
350 Quadriplegia 9 7.6 7.6 signal
351 Pneumoperitoneum 8 7.6 7.6 signal
352 Prothrombin Time Prolonged 26 7.4 7.4 signal
353 Anaphylactic Reaction 235 7.4 7.5 signal
354 Lymphopenia 60 7.4 7.4 signal
355 Bronchial Obstruction 6 7.4 7.4 signal
356 Lip Oedema 18 7.3 7.3 signal
357 Escherichia Urinary Tract Infection 18 7.3 7.3 signal
358 Cystitis Haemorrhagic 17 7.3 7.3 signal
359 Neutropenia 572 7.3 7.6 signal
360 Aplastic Anaemia 22 7.3 7.3 signal
361 Gaze Palsy 7 7.1 7.1 signal
362 Necrosis 23 7.1 7.1 signal
363 Non-cardiac Chest Pain 13 7.1 7.1 signal
364 Cholecystitis Acute 23 7.0 7.0 signal
365 Ileus 50 7.0 7.0 signal
366 Hypogammaglobulinaemia 26 7.0 7.0 signal
367 Brain Oedema 51 7.0 7.0 signal
368 Skin Striae 6 7.0 7.0 signal
369 Renal Colic 9 6.9 6.9 signal
370 Brain Abscess 10 6.8 6.8 signal
371 Mitral Valve Disease 7 6.8 6.8 signal
372 Fibrin D Dimer Increased 14 6.8 6.8 signal
373 Abdominal Infection 10 6.8 6.8 signal
374 Calculus Urinary 6 6.7 6.7 signal
375 Left Ventricular Dysfunction 26 6.7 6.8 signal
376 Varicella Zoster Virus Infection 8 6.7 6.7 signal
377 Haemodynamic Instability 29 6.7 6.7 signal
378 Neutrophil Count Decreased 155 6.6 6.7 signal
379 Intestinal Dilatation 5 6.5 6.5 signal
380 Pulmonary Infarction 9 6.5 6.5 signal
381 Intra-abdominal Haemorrhage 9 6.5 6.5 signal
382 Hypoxia 132 6.5 6.6 signal
383 Extradural Haematoma 5 6.5 6.5 signal
384 Tachycardia 331 6.4 6.6 signal
385 Apnoea 29 6.4 6.4 signal
386 Ischaemic Hepatitis 5 6.4 6.4 signal
387 Blood Immunoglobulin G Decreased 9 6.4 6.4 signal
388 Partial Seizures 19 6.4 6.4 signal
389 Myelopathy 7 6.4 6.4 signal
390 Sinus Tachycardia 52 6.3 6.4 signal
391 Metabolic Encephalopathy 11 6.3 6.3 signal
392 Thrombocytopenia 406 6.3 6.5 signal
393 Pleuritic Pain 10 6.2 6.2 signal
394 Urinary Tract Infection Bacterial 9 6.2 6.2 signal
395 Bk Virus Infection 12 6.2 6.2 signal
396 Unresponsive To Stimuli 92 6.2 6.2 signal
397 Culture Urine Positive 5 6.1 6.1 signal
398 Epstein-barr Virus Infection 22 6.1 6.1 signal
399 Encephalopathy 86 6.1 6.1 signal
400 Computerised Tomogram Abnormal 8 6.1 6.1 signal
401 Lung Opacity 9 6.0 6.0 signal
402 Drug-induced Liver Injury 107 6.0 6.0 signal
403 Splenic Infarction 6 6.0 6.0 signal
404 Nuclear Magnetic Resonance Imaging Brain Abnormal 5 5.9 5.9 signal
405 Nephrectomy 5 5.8 5.8 signal
406 Granulocyte Count Decreased 6 5.8 5.8 signal
407 Transaminases Increased 74 5.8 5.8 signal
408 Graft Versus Host Disease 24 5.7 5.7 signal
409 Cellulitis 167 5.7 5.8 signal
410 Mental Status Changes 91 5.7 5.7 signal
411 Cholestatic Liver Injury 7 5.6 5.6 signal
412 Shock 74 5.6 5.6 signal
413 Shock Haemorrhagic 26 5.5 5.5 signal
414 Urine Output Decreased 28 5.5 5.5 signal
415 Hypovolaemic Shock 15 5.4 5.4 signal
416 Hemiparesis 53 5.4 5.4 signal
417 Streptococcal Infection 17 5.3 5.3 signal
418 Serum Ferritin Increased 16 5.3 5.3 signal
419 Blood Albumin Decreased 24 5.2 5.2 signal
420 Hypernatraemia 15 5.2 5.2 signal
421 Cell Death 6 5.2 5.2 signal
422 Respiratory Tract Infection Viral 7 5.2 5.2 signal
423 Ventricular Arrhythmia 11 5.2 5.2 signal
424 Haemorrhage Intracranial 45 5.2 5.2 signal
425 Hypophagia 76 5.2 5.2 signal
426 Bone Marrow Disorder 9 5.2 5.2 signal
427 Facial Paralysis 25 5.1 5.1 signal
428 Brain Natriuretic Peptide Increased 9 5.0 5.0 signal
429 Systemic Inflammatory Response Syndrome 11 5.0 5.0 signal
430 Acute Respiratory Distress Syndrome 51 5.0 5.0 signal
431 Vascular Device Infection 13 5.0 5.0 signal
432 Intracranial Pressure Increased 16 5.0 5.0 signal
433 Clostridium Difficile Infection 62 4.9 5.0 signal
434 Stomatitis 171 4.9 4.9 signal
435 Proctalgia 18 4.8 4.8 signal
436 Polydipsia 11 4.8 4.8 signal
437 Fluid Overload 41 4.8 4.8 signal
438 Herpes Virus Infection 16 4.8 4.8 signal
439 Hydrocephalus 15 4.8 4.8 signal
440 Respiratory Failure 201 4.8 4.8 signal
441 Cerebral Atrophy 11 4.7 4.8 signal
442 Thrombocytosis 10 4.7 4.7 signal
443 Intestinal Ischaemia 15 4.7 4.7 signal
444 Aspartate Aminotransferase Increased 145 4.7 4.8 signal
445 Stridor 8 4.7 4.7 signal
446 Distributive Shock 6 4.7 4.7 signal
447 Pallor 74 4.7 4.7 signal
448 Pleural Effusion 165 4.7 4.7 signal
449 Pneumocystis Jirovecii Pneumonia 27 4.7 4.7 signal
450 Hypercapnia 8 4.6 4.6 signal
451 Endophthalmitis 16 4.6 4.6 signal
452 Protein Total Decreased 10 4.6 4.6 signal
453 Acute Hepatic Failure 36 4.6 4.6 signal
454 Peroneal Nerve Palsy 15 4.6 4.6 signal
455 Blood Bicarbonate Decreased 5 4.5 4.5 signal
456 Hypercholesterolaemia 25 4.5 4.5 signal
457 Hypercoagulation 5 4.5 4.5 signal
458 Areflexia 7 4.5 4.5 signal
459 Portal Hypertension 8 4.5 4.5 signal
460 Oral Disorder 19 4.5 4.5 signal
461 Metabolic Disorder 15 4.5 4.5 signal
462 Haematological Infection 6 4.5 4.5 signal
463 Gastrointestinal Injury 7 4.5 4.5 signal
464 Oliguria 16 4.4 4.5 signal
465 Leukopenia 128 4.4 4.5 signal
466 Blood Triglycerides Increased 45 4.4 4.4 signal
467 Electroencephalogram Abnormal 8 4.4 4.4 signal
468 Cystitis 81 4.4 4.4 signal
469 Adrenal Insufficiency 30 4.3 4.3 signal
470 Petechiae 26 4.3 4.3 signal
471 Anal Haemorrhage 7 4.3 4.3 signal
472 Proctitis 7 4.3 4.3 signal
473 Foetal Growth Restriction 15 4.3 4.3 signal
474 Lung Infection 39 4.3 4.3 signal
475 Dialysis 35 4.2 4.3 signal
476 Staphylococcal Infection 81 4.2 4.2 signal
477 Stem Cell Transplant 6 4.2 4.2 signal
478 Lung Abscess 5 4.1 4.1 signal
479 Cerebral Haematoma 8 4.1 4.1 signal
480 Neutropenic Sepsis 17 4.1 4.1 signal
481 Appendicitis 22 4.1 4.1 signal
482 Wound Dehiscence 8 4.1 4.1 signal
483 Neoplasm Recurrence 8 4.1 4.1 signal
484 Osteonecrosis 78 4.1 4.1 signal
485 Electrolyte Imbalance 27 4.1 4.1 signal
486 Eye Movement Disorder 16 4.0 4.0 signal
487 Generalised Tonic-clonic Seizure 38 4.0 4.0 signal
488 Hypotension 464 4.0 4.1 signal
489 Hepatic Lesion 10 4.0 4.0 signal
490 Ocular Icterus 10 4.0 4.0 signal
491 Subdural Haematoma 33 4.0 4.0 signal
492 Hepatitis Toxic 6 3.9 3.9 signal
493 Hemiplegia 19 3.9 3.9 signal
494 Polyneuropathy 27 3.9 3.9 signal
495 Hypokalaemia 104 3.9 3.9 signal
496 Facial Paresis 8 3.9 3.9 signal
497 Hepatic Encephalopathy 21 3.9 3.9 signal
498 Anal Fissure 12 3.9 3.9 signal
499 Fungal Skin Infection 9 3.9 3.9 signal
500 Pyrexia 777 3.9 4.1 signal
501 Pericardial Effusion 51 3.8 3.8 signal
502 Abdominal Pain 512 3.8 3.9 signal
503 Odynophagia 13 3.8 3.8 signal
504 Anuria 19 3.8 3.8 signal
505 Hyperuricaemia 9 3.8 3.8 signal
506 Hyponatraemia 123 3.8 3.8 signal
507 Dyslipidaemia 11 3.7 3.7 signal
508 Type 1 Diabetes Mellitus 13 3.7 3.7 signal
509 Inappropriate Antidiuretic Hormone Secretion 22 3.7 3.7 signal
510 Cytokine Release Syndrome 41 3.7 3.7 signal
511 Body Temperature Increased 44 3.7 3.7 signal
512 Chronic Sinusitis 8 3.7 3.7 signal
513 Lung Infiltration 19 3.7 3.7 signal
514 Haemodialysis 18 3.7 3.7 signal
515 Generalised Oedema 26 3.6 3.6 signal
516 Cerebral Haemorrhage 75 3.6 3.6 signal
517 Pulmonary Mass 31 3.6 3.6 signal
518 Hypervolaemia 10 3.6 3.6 signal
519 Incorrect Route Of Product Administration 35 3.6 3.6 signal
520 Paronychia 9 3.6 3.6 signal
521 Guillain-barre Syndrome 10 3.6 3.6 signal
522 Platelet Count Decreased 218 3.5 3.6 signal
523 Toxic Encephalopathy 10 3.5 3.5 signal
524 Large Intestine Perforation 14 3.5 3.5 signal
525 Abdominal Tenderness 10 3.5 3.5 signal
526 Intraventricular Haemorrhage 5 3.5 3.5 signal
527 Necrotising Fasciitis 7 3.4 3.4 signal
528 Jaundice Cholestatic 7 3.4 3.4 signal
529 Cardio-respiratory Arrest 83 3.4 3.4 signal
530 Conjunctival Hyperaemia 7 3.4 3.4 signal
531 Cachexia 10 3.4 3.4 signal
532 Chest X-ray Abnormal 6 3.3 3.3 signal
533 Lactic Acidosis 62 3.3 3.3 signal
534 Cardiac Dysfunction 7 3.3 3.3 signal
535 Anaphylactic Shock 49 3.3 3.3 signal
536 Hypophosphataemia 14 3.3 3.3 signal
537 Agranulocytosis 35 3.3 3.3 signal
538 Low Birth Weight Baby 15 3.3 3.3 signal
539 Hypovolaemia 11 3.2 3.2 signal
540 Orthopnoea 6 3.2 3.2 signal
541 Catheter Site Infection 7 3.2 3.2 signal
542 Poor Peripheral Circulation 8 3.2 3.2 signal
543 Hepatitis Acute 12 3.2 3.2 signal
544 Gastric Perforation 5 3.2 3.2 signal
545 Blood Phosphorus Increased 5 3.2 3.2 signal
546 Seizure 210 3.2 3.2 signal
547 Otitis Media 6 3.1 3.1 signal
548 Abdominal Abscess 8 3.1 3.1 signal
549 Bradycardia 96 3.1 3.1 signal
550 Cardiopulmonary Failure 7 3.1 3.1 signal
551 Hypersensitivity 331 3.1 3.1 signal
552 Respiratory Acidosis 7 3.1 3.1 signal
553 Acute Respiratory Failure 34 3.1 3.1 signal
554 Oxygen Saturation Decreased 99 3.1 3.1 signal
555 Mouth Haemorrhage 13 3.1 3.1 signal
556 Neutrophil Count Abnormal 5 3.1 3.1 signal
557 Photophobia 33 3.0 3.1 signal
558 Clostridial Infection 6 3.0 3.0 signal
559 Hypocalcaemia 33 3.0 3.0 signal
560 Pyelonephritis 15 3.0 3.0 signal
561 Periorbital Oedema 9 3.0 3.0 signal
562 Cyanosis 27 3.0 3.0 signal
563 Carotid Artery Stenosis 6 2.9 2.9 signal
564 Liver Injury 41 2.9 2.9 signal
565 Hypothermia 17 2.9 2.9 signal
566 Hepatic Function Abnormal 62 2.9 2.9 signal
567 Central Venous Catheterisation 5 2.9 2.9 signal
568 Duodenitis 5 2.8 2.8 signal
569 Anaemia 310 2.8 2.8 signal
570 Acute Kidney Injury 247 2.8 2.8 signal
571 Nephropathy Toxic 18 2.8 2.8 signal
572 Immunosuppression 14 2.8 2.8 signal
573 Blood Creatinine Decreased 5 2.8 2.8 no signal
574 Polyuria 13 2.7 2.7 signal
575 Motor Dysfunction 16 2.7 2.7 signal
576 Haematemesis 40 2.7 2.7 signal
577 Subarachnoid Haemorrhage 16 2.7 2.7 signal
578 Faeces Hard 6 2.7 2.7 signal
579 Bronchospasm 22 2.6 2.7 signal
580 Failure To Thrive 8 2.6 2.6 signal
581 Metabolic Acidosis 48 2.6 2.6 signal
582 Pneumothorax 24 2.6 2.6 signal
583 Electrocardiogram St Segment Elevation 5 2.6 2.6 no signal
584 Face Oedema 25 2.5 2.5 signal
585 Cardiac Arrest 119 2.5 2.5 signal
586 Cerebral Infarction 35 2.5 2.5 signal
587 Pathogen Resistance 13 2.5 2.5 signal
588 Transfusion 15 2.5 2.5 signal
589 Intestinal Perforation 16 2.5 2.5 signal
590 Fluid Intake Reduced 7 2.4 2.4 signal
591 Acute Myeloid Leukaemia 22 2.4 2.4 signal
592 Infusion Related Reaction 93 2.4 2.4 signal
593 Abscess Limb 6 2.4 2.4 no signal
594 Haematotoxicity 13 2.4 2.4 signal
595 Oral Candidiasis 18 2.4 2.4 signal
596 Cytomegalovirus Infection 23 2.4 2.4 signal
597 Dysarthria 52 2.4 2.4 signal
598 Hypoglycaemia 67 2.4 2.4 signal
599 White Blood Cell Count Decreased 149 2.4 2.4 signal
600 Endocarditis 7 2.4 2.4 signal
601 Eyelid Oedema 16 2.4 2.4 signal
602 Lip Swelling 45 2.3 2.3 signal
603 Cardiotoxicity 12 2.3 2.3 signal
604 Bronchiectasis 9 2.3 2.3 signal
605 Second Primary Malignancy 11 2.3 2.3 signal
606 International Normalised Ratio Increased 38 2.3 2.3 signal
607 Neuralgia 32 2.3 2.3 signal
608 Liver Function Test Increased 28 2.3 2.3 signal
609 Blood Urea Increased 22 2.3 2.3 signal
610 Anal Abscess 7 2.2 2.2 no signal
611 Laryngeal Oedema 8 2.2 2.2 signal
612 Ischaemic Stroke 23 2.2 2.2 signal
613 Vomiting 603 2.2 2.3 signal
614 Infusion Site Extravasation 8 2.2 2.2 signal
615 Leukaemia 12 2.2 2.2 signal
616 Myopathy 11 2.2 2.2 signal
617 Ventricular Tachycardia 21 2.2 2.2 signal
618 Jaundice 34 2.2 2.2 signal
619 Neuropathy Peripheral 119 2.2 2.2 signal
620 Supraventricular Tachycardia 12 2.2 2.2 signal
621 Metastasis 9 2.2 2.2 signal
622 Pulmonary Alveolar Haemorrhage 7 2.2 2.2 no signal
623 Blood Calcium Decreased 14 2.1 2.1 signal
624 Neurological Symptom 7 2.1 2.1 no signal
625 Candidiasis 5 2.1 2.1 no signal
626 Myositis 11 2.1 2.1 signal
627 Blood Sodium Decreased 23 2.1 2.1 signal
628 Small Intestinal Obstruction 15 2.1 2.1 signal
629 Anaphylactoid Reaction 5 2.1 2.1 no signal
630 Mucous Stools 6 2.1 2.1 no signal
631 Diabetic Ketoacidosis 29 2.1 2.1 signal
632 Hyperpyrexia 5 2.1 2.1 no signal
633 Rales 7 2.1 2.1 no signal
634 Pneumonia Bacterial 11 2.1 2.1 signal
635 Hypotonia 12 2.1 2.1 signal
636 Brain Injury 12 2.1 2.1 signal
637 Haemoglobin Decreased 122 2.0 2.1 signal
638 Diarrhoea Haemorrhagic 11 2.0 2.0 signal
639 Blood Alkaline Phosphatase Increased 29 2.0 2.0 signal
640 Ecchymosis 8 2.0 2.0 no signal
641 Infarction 8 2.0 2.0 no signal
642 Aphasia 35 2.0 2.0 no signal
643 Gangrene 7 2.0 2.0 no signal
644 Skin Necrosis 6 2.0 2.0 no signal
645 Tonsillitis 6 2.0 2.0 no signal
646 Multi-organ Failure 20 2.0 2.0 no signal
647 Infection 164 2.0 2.0 no signal
648 Thrombotic Microangiopathy 11 2.0 2.0 no signal
649 Pneumonia 362 1.9 2.0 no signal
650 Rhinitis 9 1.9 1.9 no signal
651 Oral Pain 25 1.9 1.9 no signal
652 Circulatory Collapse 19 1.9 1.9 no signal
653 Angioedema 49 1.9 1.9 no signal
654 Gastroenteritis 16 1.9 1.9 no signal
655 Hepatitis 28 1.9 1.9 no signal
656 Screaming 7 1.9 1.9 no signal
657 Blood Pressure Decreased 72 1.9 1.9 no signal
658 Ischaemia 5 1.9 1.9 no signal
659 Refusal Of Treatment By Patient 7 1.8 1.8 no signal
660 Flank Pain 10 1.8 1.8 no signal
661 Gastrointestinal Toxicity 5 1.8 1.8 no signal
662 Hyperkalaemia 37 1.8 1.8 no signal
663 Myocarditis 12 1.8 1.8 no signal
664 Hyperthermia 8 1.8 1.8 no signal
665 Pulmonary Embolism 100 1.8 1.8 no signal
666 Granulocytopenia 6 1.8 1.8 no signal
667 Deep Vein Thrombosis 68 1.8 1.8 no signal
668 Haemolysis 8 1.8 1.8 no signal
669 Skin Lesion 28 1.8 1.8 no signal
670 Gastrointestinal Inflammation 8 1.8 1.8 no signal
671 Dehydration 136 1.8 1.8 no signal
672 Torsade De Pointes 8 1.8 1.8 no signal
673 Gastrointestinal Sounds Abnormal 5 1.8 1.8 no signal
674 Breath Sounds Abnormal 5 1.7 1.7 no signal
675 Lethargy 58 1.7 1.7 no signal
676 Chills 118 1.7 1.7 no signal
677 Pulmonary Oedema 45 1.7 1.7 no signal
678 Skin Infection 11 1.7 1.7 no signal
679 Altered State Of Consciousness 21 1.7 1.7 no signal
680 Cholangitis 6 1.7 1.7 no signal
681 Hepatic Cirrhosis 18 1.7 1.7 no signal
682 Depressed Level Of Consciousness 38 1.7 1.7 no signal
683 Lymphocyte Count Decreased 17 1.7 1.7 no signal
684 Grand Mal Convulsion 9 1.7 1.7 no signal
685 Acute Coronary Syndrome 8 1.7 1.7 no signal
686 Blindness Transient 7 1.6 1.6 no signal
687 Cholelithiasis 31 1.6 1.6 no signal
688 Therapy Partial Responder 14 1.6 1.6 no signal
689 Bruxism 5 1.6 1.6 no signal
690 Drug Level Below Therapeutic 5 1.6 1.6 no signal
691 Swelling Face 59 1.6 1.6 no signal
692 Ventricular Fibrillation 10 1.5 1.5 no signal
693 Haemorrhagic Stroke 7 1.5 1.5 no signal
694 Eyelid Ptosis 9 1.5 1.5 no signal
695 Status Epilepticus 10 1.5 1.5 no signal
696 Renal Failure 117 1.5 1.5 no signal
697 Drooling 6 1.5 1.5 no signal
698 Haemoptysis 24 1.5 1.5 no signal
699 Liver Disorder 38 1.5 1.5 no signal
700 Drug Hypersensitivity 166 1.5 1.5 no signal
701 Urticaria 142 1.5 1.5 no signal
702 Product Use In Unapproved Indication 207 1.5 1.5 no signal
703 Ejection Fraction Decreased 13 1.4 1.4 no signal
704 Respiratory Disorder 25 1.4 1.4 no signal
705 Oedema 45 1.4 1.4 no signal
706 Therapy Non-responder 37 1.4 1.4 no signal
707 Respiratory Tract Infection 21 1.4 1.4 no signal
708 Haematoma 21 1.4 1.4 no signal
709 Gastritis 21 1.4 1.4 no signal
710 Toxic Skin Eruption 8 1.4 1.4 no signal
711 Anal Incontinence 7 1.4 1.4 no signal
712 Respiratory Rate Increased 7 1.4 1.4 no signal
713 Neutrophil Count Increased 8 1.3 1.3 no signal
714 Throat Tightness 21 1.3 1.3 no signal
715 General Physical Health Deterioration 89 1.3 1.3 no signal
716 Epistaxis 58 1.3 1.3 no signal
717 Incoherent 5 1.3 1.3 no signal
718 Ventricular Extrasystoles 8 1.3 1.3 no signal
719 Muscular Weakness 87 1.3 1.3 no signal
720 Gastrointestinal Haemorrhage 64 1.3 1.3 no signal
721 Mouth Ulceration 16 1.3 1.3 no signal
722 Upper Respiratory Tract Infection 35 1.3 1.3 no signal
723 Covid-19 Pneumonia 9 1.3 1.3 no signal
724 Thrombosis 61 1.3 1.3 no signal
725 Delirium 26 1.3 1.3 no signal
726 Sensory Loss 6 1.3 1.3 no signal
727 Oesophagitis 8 1.3 1.3 no signal
728 Hypertension 155 1.3 1.3 no signal
729 Hypercalcaemia 9 1.3 1.3 no signal
730 Blood Creatinine Increased 47 1.2 1.2 no signal
731 Diabetes Mellitus 55 1.2 1.2 no signal
732 Heart Rate Increased 71 1.2 1.2 no signal
733 Oropharyngeal Pain 66 1.2 1.2 no signal
734 Toxicity To Various Agents 119 1.2 1.2 no signal
735 Cough 197 1.2 1.2 no signal
736 Mydriasis 9 1.2 1.2 no signal
737 Haematocrit Decreased 14 1.2 1.2 no signal
738 Cardiogenic Shock 10 1.2 1.2 no signal
739 Skin Hyperpigmentation 6 1.2 1.2 no signal
740 Haematuria 24 1.2 1.2 no signal
741 Myelodysplastic Syndrome 10 1.2 1.2 no signal
742 Drug Level Decreased 7 1.2 1.2 no signal
743 Interstitial Lung Disease 33 1.2 1.2 no signal
744 Gastric Ulcer 13 1.2 1.2 no signal
745 Immunodeficiency 10 1.2 1.2 no signal
746 Herpes Zoster 39 1.2 1.2 no signal
747 Hepatic Enzyme Increased 46 1.2 1.2 no signal
748 Lower Gastrointestinal Haemorrhage 5 1.2 1.2 no signal
749 Pneumonitis 18 1.1 1.1 no signal
750 Agitation 49 1.1 1.1 no signal
751 C-reactive Protein Increased 24 1.1 1.1 no signal
752 Retching 14 1.1 1.1 no signal
753 Abdominal Distension 68 1.1 1.1 no signal
754 Peripheral Coldness 9 1.1 1.1 no signal
755 Liver Function Test Abnormal 19 1.1 1.1 no signal
756 Decreased Appetite 150 1.1 1.1 no signal
757 Aspiration 7 1.1 1.1 no signal
758 Pharyngeal Oedema 10 1.1 1.1 no signal
759 Nervous System Disorder 20 1.1 1.1 no signal
760 Hypothyroidism 20 1.1 1.1 no signal
761 Peritonitis 13 1.1 1.1 no signal
762 Neoplasm Progression 22 1.1 1.1 no signal
763 Paralysis 9 1.1 1.1 no signal
764 Chromaturia 14 1.1 1.1 no signal
765 Ear Pain 12 1.1 1.1 no signal
766 Asphyxia 5 1.1 1.1 no signal
767 Rhinorrhoea 39 1.0 1.0 no signal
768 Gastric Haemorrhage 7 1.0 1.0 no signal
769 Drug Level Increased 10 1.0 1.0 no signal
770 Head Injury 19 1.0 1.0 no signal
771 Salivary Hypersecretion 6 1.0 1.0 no signal
772 Vasculitis 7 1.0 1.0 no signal
773 Sinusitis 61 1.0 1.0 no signal
774 Melaena 13 1.0 1.0 no signal
775 Ataxia 7 1.0 1.0 no signal
776 Myoclonus 7 1.0 1.0 no signal
777 Cardiac Failure 47 1.0 1.0 no signal
778 Central Nervous System Lesion 8 1.0 1.0 no signal
779 Lung Disorder 28 1.0 1.0 no signal
780 Erythema 117 1.0 1.0 no signal
781 Incontinence 6 1.0 1.0 no signal
782 Pharyngitis 7 1.0 1.0 no signal
783 Rectal Haemorrhage 24 1.0 1.0 no signal
784 Osteomyelitis 10 1.0 1.0 no signal
785 Hypokinesia 8 0.9 0.9 no signal
786 Retinal Detachment 5 0.9 0.9 no signal
787 Dyskinesia 22 0.9 0.9 no signal
788 Skin Ulcer 14 0.9 0.9 no signal
789 Syncope 54 0.9 0.9 no signal
790 Drug Interaction 85 0.9 0.9 no signal
791 Haemorrhage 56 0.9 0.9 no signal
792 Pain In Jaw 15 0.9 0.9 no signal
793 Disease Progression 62 0.9 0.9 no signal
794 Sars-cov-2 Test Positive 7 0.9 0.9 no signal
795 Dizziness Postural 5 0.9 0.9 no signal
796 Throat Irritation 23 0.9 0.9 no signal
797 Vitreous Floaters 5 0.9 0.9 no signal
798 Constipation 111 0.9 0.9 no signal
799 Nausea 404 0.9 0.9 no signal
800 Hypomagnesaemia 7 0.9 0.9 no signal
801 Gallbladder Disorder 9 0.9 0.9 no signal
802 Renal Injury 15 0.9 0.9 no signal
803 Presyncope 12 0.9 0.9 no signal
804 Crying 18 0.9 0.8 no signal
805 Oedema Peripheral 60 0.8 0.8 no signal
806 Haematochezia 27 0.8 0.8 no signal
807 Pain In Extremity 144 0.8 0.8 no signal
808 Dermatitis Allergic 6 0.8 0.8 no signal
809 Urinary Retention 16 0.8 0.8 no signal
810 Increased Appetite 9 0.8 0.8 no signal
811 Covid-19 84 0.8 0.8 no signal
812 Cardiomyopathy 7 0.8 0.8 no signal
813 Medication Error 26 0.8 0.8 no signal
814 Feeling Cold 13 0.8 0.8 no signal
815 Blood Potassium Decreased 14 0.8 0.8 no signal
816 Irritability 28 0.8 0.8 no signal
817 Flushing 47 0.8 0.8 no signal
818 Epilepsy 14 0.8 0.8 no signal
819 Blood Count Abnormal 7 0.8 0.8 no signal
820 Complication Associated With Device 6 0.8 0.8 no signal
821 Dyspnoea Exertional 17 0.8 0.8 no signal
822 Dysphagia 42 0.8 0.8 no signal
823 Bone Pain 26 0.8 0.8 no signal
824 Toothache 8 0.8 0.8 no signal
825 White Blood Cell Count Increased 17 0.8 0.8 no signal
826 Wheezing 26 0.8 0.8 no signal
827 Abscess 7 0.8 0.8 no signal
828 Respiratory Arrest 12 0.7 0.7 no signal
829 Oral Discomfort 6 0.7 0.7 no signal
830 Drug Resistance 11 0.7 0.7 no signal
831 Confusional State 69 0.7 0.7 no signal
832 Gait Inability 14 0.7 0.7 no signal
833 Pericarditis 7 0.7 0.7 no signal
834 Pharyngeal Swelling 4 0.7 0.7 no signal
835 Post Procedural Complication 8 0.7 0.7 no signal
836 Blood Pressure Fluctuation 10 0.7 0.7 no signal
837 Convulsion 24 0.7 0.7 no signal
838 Asthenia 155 0.7 0.7 no signal
839 Headache 258 0.7 0.7 no signal
840 Chest Pain 76 0.7 0.7 no signal
841 Respiratory Depression 5 0.7 0.7 no signal
842 Eye Swelling 15 0.7 0.7 no signal
843 No Therapeutic Response 5 0.7 0.7 no signal
844 Disorientation 16 0.7 0.7 no signal
845 Orthostatic Hypotension 7 0.7 0.7 no signal
846 Toxic Epidermal Necrolysis 6 0.7 0.7 no signal
847 Drug Eruption 7 0.7 0.7 no signal
848 Gastrointestinal Disorder 35 0.7 0.7 no signal
849 Back Pain 91 0.7 0.7 no signal
850 Off Label Use 337 0.7 0.7 no signal
851 Leukocytosis 7 0.7 0.7 no signal
852 Renal Disorder 18 0.7 0.7 no signal
853 Dyspnoea 218 0.7 0.7 no signal
854 Rash Erythematous 18 0.7 0.7 no signal
855 Diarrhoea 246 0.7 0.7 no signal
856 Chest Discomfort 39 0.7 0.7 no signal
857 Hallucination, Visual 8 0.7 0.7 no signal
858 Immune System Disorder 5 0.7 0.7 no signal
859 Disease Recurrence 18 0.6 0.6 no signal
860 Pharyngitis Streptococcal 4 0.6 0.6 no signal
861 Heart Rate Decreased 13 0.6 0.6 no signal
862 Tremor 61 0.6 0.6 no signal
863 Blood Cholesterol Increased 17 0.6 0.6 no signal
864 Choking 7 0.6 0.6 no signal
865 Renal Impairment 30 0.6 0.6 no signal
866 Upper Gastrointestinal Haemorrhage 6 0.6 0.6 no signal
867 Rash 154 0.6 0.6 no signal
868 Blindness Unilateral 5 0.6 0.6 no signal
869 Dysuria 13 0.6 0.6 no signal
870 Red Blood Cell Count Decreased 10 0.6 0.6 no signal
871 Muscle Twitching 8 0.6 0.6 no signal
872 Loss Of Consciousness 44 0.6 0.6 no signal
873 Dysstasia 10 0.6 0.6 no signal
874 Psychotic Disorder 10 0.6 0.6 no signal
875 Somnolence 68 0.6 0.6 no signal
876 Urinary Incontinence 10 0.6 0.6 no signal
877 Neuroleptic Malignant Syndrome 4 0.6 0.6 no signal
878 Abdominal Pain Upper 69 0.6 0.6 no signal
879 Coma 16 0.6 0.6 no signal
880 Hyperhidrosis 43 0.6 0.6 no signal
881 Electrocardiogram Qt Prolonged 12 0.6 0.6 no signal
882 Oesophageal Carcinoma 10 0.6 0.6 no signal
883 Abnormal Behaviour 13 0.6 0.6 no signal
884 Abdominal Pain Lower 8 0.5 0.5 no signal
885 Blood Lactate Dehydrogenase Increased 5 0.5 0.5 no signal
886 Affect Lability 3 0.5 0.5 no signal
887 Lacrimation Increased 9 0.5 0.5 no signal
888 Menorrhagia 6 0.5 0.5 no signal
889 Underdose 22 0.5 0.5 no signal
890 Therapeutic Response Decreased 18 0.5 0.5 no signal
891 Full Blood Count Decreased 6 0.5 0.5 no signal
892 Swelling 27 0.5 0.5 no signal
893 Cerebrovascular Accident 48 0.5 0.5 no signal
894 Gastroenteritis Viral 5 0.5 0.5 no signal
895 Fluid Retention 14 0.5 0.5 no signal
896 Blood Creatine Phosphokinase Increased 8 0.5 0.5 no signal
897 Laboratory Test Abnormal 8 0.5 0.5 no signal
898 Contusion 26 0.5 0.5 no signal
899 Rash Generalised 7 0.5 0.5 no signal
900 Flatulence 15 0.5 0.5 no signal
901 Blood Urine Present 5 0.5 0.5 no signal
902 Nephrolithiasis 12 0.5 0.5 no signal
903 Paraesthesia 41 0.4 0.4 no signal
904 Rash Pruritic 14 0.4 0.4 no signal
905 Weight Decreased 72 0.4 0.4 no signal
906 Drug Administration Error 8 0.4 0.4 no signal
907 Dystonia 5 0.4 0.4 no signal
908 Malignant Neoplasm Progression 26 0.4 0.4 no signal
909 Therapy Cessation 13 0.4 0.4 no signal
910 Movement Disorder 8 0.4 0.4 no signal
911 Feeling Hot 15 0.4 0.4 no signal
912 Dermatitis 5 0.4 0.4 no signal
913 Death 207 0.4 0.4 no signal
914 Skin Discolouration 11 0.4 0.4 no signal
915 Nasal Congestion 14 0.4 0.4 no signal
916 Cognitive Disorder 11 0.4 0.4 no signal
917 Transient Ischaemic Attack 8 0.4 0.4 no signal
918 Gait Disturbance 45 0.4 0.4 no signal
919 Productive Cough 11 0.4 0.4 no signal
920 Renal Failure Acute 10 0.4 0.4 no signal
921 Neck Pain 13 0.4 0.4 no signal
922 Faeces Discoloured 5 0.4 0.4 no signal
923 Fall 76 0.4 0.4 no signal
924 Lymphadenopathy 8 0.4 0.4 no signal
925 Malaise 99 0.4 0.4 no signal
926 Blood Glucose Increased 42 0.4 0.4 no signal
927 Treatment Failure 18 0.4 0.4 no signal
928 Drug Intolerance 21 0.4 0.4 no signal
929 Hypoaesthesia 32 0.4 0.4 no signal
930 Speech Disorder 11 0.4 0.4 no signal
931 Serotonin Syndrome 4 0.4 0.4 no signal
932 Blood Glucose Decreased 10 0.4 0.4 no signal
933 Pruritus 77 0.4 0.3 no signal
934 Acute Myocardial Infarction 6 0.3 0.3 no signal
935 Urinary Tract Infection 34 0.3 0.3 no signal
936 Abasia 5 0.3 0.3 no signal
937 Extrapyramidal Disorder 5 0.3 0.3 no signal
938 Condition Aggravated 60 0.3 0.3 no signal
939 Dizziness 97 0.3 0.3 no signal
940 Emotional Disorder 6 0.3 0.3 no signal
941 Diplopia 5 0.3 0.3 no signal
942 Rhabdomyolysis 8 0.3 0.3 no signal
943 Blood Pressure Increased 29 0.3 0.3 no signal
944 Therapy Interrupted 13 0.3 0.3 no signal
945 Influenza 21 0.3 0.3 no signal
946 Premature Delivery 3 0.3 0.3 no signal
947 Treatment Noncompliance 10 0.3 0.3 no signal
948 Mental Disorder 8 0.3 0.3 no signal
949 Eye Pain 10 0.3 0.3 no signal
950 Fatigue 139 0.3 0.3 no signal
951 Pain 110 0.3 0.3 no signal
952 Myalgia 30 0.3 0.3 no signal
953 Tinnitus 8 0.3 0.3 no signal
954 Foetal Exposure During Pregnancy 14 0.3 0.3 no signal
955 Product Use Issue 32 0.3 0.3 no signal
956 Musculoskeletal Stiffness 15 0.3 0.3 no signal
957 Palmar-plantar Erythrodysaesthesia Syndrome 4 0.3 0.3 no signal
958 Anxiety 48 0.3 0.3 no signal
959 Arrhythmia 8 0.3 0.3 no signal
960 Discomfort 10 0.3 0.3 no signal
961 Weight Increased 36 0.3 0.3 no signal
962 Limb Discomfort 5 0.3 0.3 no signal
963 Intestinal Obstruction 6 0.3 0.3 no signal
964 Adverse Event 14 0.3 0.3 no signal
965 Musculoskeletal Pain 8 0.3 0.3 no signal
966 Ocular Hyperaemia 7 0.3 0.3 no signal
967 Drug Ineffective 195 0.3 0.2 no signal
968 Bronchitis 11 0.3 0.3 no signal
969 Vision Blurred 20 0.3 0.3 no signal
970 Drug Ineffective For Unapproved Indication 8 0.2 0.2 no signal
971 Peripheral Swelling 22 0.2 0.2 no signal
972 Suicidal Ideation 13 0.2 0.2 no signal
973 Vaginal Haemorrhage 6 0.2 0.2 no signal
974 Mobility Decreased 10 0.2 0.2 no signal
975 Drug Effect Incomplete 5 0.2 0.2 no signal
976 Arthralgia 55 0.2 0.2 no signal
977 Emotional Distress 16 0.2 0.2 no signal
978 Blister 7 0.2 0.2 no signal
979 Dysphonia 7 0.2 0.2 no signal
980 Visual Impairment 14 0.2 0.2 no signal
981 Abdominal Discomfort 19 0.2 0.2 no signal
982 Therapeutic Product Effect Incomplete 8 0.2 0.2 no signal
983 Palpitations 13 0.2 0.2 no signal
984 Inappropriate Schedule Of Product Administration 18 0.2 0.2 no signal
985 Aggression 5 0.2 0.2 no signal
986 Unevaluable Event 7 0.2 0.2 no signal
987 Disturbance In Attention 5 0.2 0.2 no signal
988 Balance Disorder 8 0.2 0.2 no signal
989 Depression 20 0.2 0.1 no signal
990 Insomnia 23 0.1 0.1 no signal
991 Sleep Disorder 6 0.1 0.1 no signal
992 Atrial Fibrillation 8 0.1 0.1 no signal
993 Intentional Product Use Issue 7 0.1 0.1 no signal
994 Chronic Kidney Disease 6 0.1 0.1 no signal
995 Adverse Drug Reaction 7 0.1 0.1 no signal
996 Alopecia 15 0.1 0.1 no signal
997 Gastrooesophageal Reflux Disease 6 0.1 0.1 no signal
998 Memory Impairment 10 0.1 0.1 no signal
999 Skin Exfoliation 6 0.1 0.1 no signal
1000 Hallucination 5 0.1 0.1 no signal
1001 Feeling Abnormal 15 0.1 0.1 no signal
1002 Overdose 11 0.1 0.1 no signal
1003 Nasopharyngitis 9 0.1 0.1 no signal
1004 Muscle Spasms 8 0.1 0.1 no signal
1005 Myocardial Infarction 7 0.1 0.1 no signal
1006 Hospitalisation 6 0.1 0.1 no signal
1007 No Adverse Event 6 0.1 0.1 no signal