OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Phytonadione

1,116 flagged reaction(s) · 47,803 total co-reports · max PRR 5,908.3
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Appendicolith 265 5,908.3 6,099.9 signal
2 Sleep Disorder Therapy 130 5,904.1 5,996.5 signal
3 Antacid Therapy 84 5,886.0 5,945.2 signal
4 Analgesic Therapy 125 1,722.3 1,748.1 signal
5 Drug Therapy 112 1,346.5 1,364.6 signal
6 Anticoagulant Therapy 82 1,047.4 1,057.7 signal
7 Congenital Hiatus Hernia 56 842.6 848.2 signal
8 Malignant Melanoma Stage 0 43 775.4 779.4 signal
9 Bacteroides Infection 39 440.8 442.8 signal
10 Hyper Ige Syndrome 17 434.3 435.2 signal
11 Hyperphosphataemia 164 208.6 212.7 signal
12 Bronchopulmonary Aspergillosis Allergic 63 183.5 184.9 signal
13 Blood Phosphorus Increased 183 179.0 183.0 signal
14 Factor V Inhibition 13 176.1 176.4 signal
15 Cutaneous Mucormycosis 11 163.5 163.7 signal
16 Vitamin K Deficiency 18 117.7 118.0 signal
17 Total Lung Capacity Decreased 68 110.2 111.1 signal
18 Restrictive Cardiomyopathy 11 92.7 92.8 signal
19 Activated Partial Thromboplastin Time Prolonged 153 77.2 78.6 signal
20 Appendicitis 275 75.8 78.3 signal
21 Iron Deficiency 130 74.9 76.0 signal
22 Infective Pulmonary Exacerbation Of Cystic Fibrosis 141 65.6 66.7 signal
23 Blood Uric Acid Increased 147 65.0 66.1 signal
24 Necrotising Enterocolitis Neonatal 10 63.4 63.4 signal
25 Hypophosphataemia 176 61.0 62.3 signal
26 Aortic Stenosis 82 59.9 60.5 signal
27 Lung Opacity 60 59.3 59.7 signal
28 Myasthenia Gravis 181 58.5 59.7 signal
29 Hyphaema 12 58.2 58.2 signal
30 Ventricular Fibrillation 249 56.8 58.5 signal
31 Intraventricular Haemorrhage Neonatal 10 52.0 52.0 signal
32 Cardiogenic Shock 270 47.9 49.5 signal
33 Pleuritic Pain 49 44.7 45.0 signal
34 Cystic Fibrosis Respiratory Infection Suppression 15 42.1 42.2 signal
35 Jaundice Neonatal 28 37.2 37.3 signal
36 Nipple Disorder 9 36.5 36.6 signal
37 Respiratory Symptom 40 36.0 36.2 signal
38 Enterococcal Sepsis 11 33.9 34.0 signal
39 Terminal Ileitis 8 33.4 33.5 signal
40 Troponin Increased 100 33.4 33.8 signal
41 Multiple Organ Dysfunction Syndrome 352 31.8 33.1 signal
42 Ascites 366 31.3 32.7 signal
43 Cystic Fibrosis 69 31.2 31.5 signal
44 C-reactive Protein Decreased 8 30.9 30.9 signal
45 Coagulation Time Prolonged 19 30.7 30.7 signal
46 Discoloured Vomit 11 29.2 29.3 signal
47 Blood Calcium Increased 100 28.6 29.0 signal
48 Blood Fibrinogen Increased 9 28.4 28.4 signal
49 Benign Prostatic Hyperplasia 58 28.1 28.3 signal
50 Breath Sounds Abnormal 51 26.0 26.1 signal
51 Incorrect Route Of Product Administration 171 25.5 26.1 signal
52 Symmetrical Drug-related Intertriginous And Flexural Exanthema 8 25.3 25.3 signal
53 Heart Transplant 9 25.1 25.2 signal
54 Choroidal Effusion 8 25.1 25.1 signal
55 Limb Malformation 8 25.0 25.0 signal
56 Bacterial Infection 180 24.3 24.8 signal
57 Pneumonia Staphylococcal 19 24.2 24.2 signal
58 Neonatal Disorder 15 23.6 23.6 signal
59 Intestinal Dilatation 12 22.7 22.8 signal
60 Hyperlipidaemia 108 22.6 22.9 signal
61 Anticoagulation Drug Level Above Therapeutic 13 21.1 21.1 signal
62 Dysmorphism 19 20.0 20.0 signal
63 Klebsiella Sepsis 9 20.0 20.0 signal
64 Epicondylitis 12 19.9 20.0 signal
65 Gastric Ph Decreased 8 19.5 19.5 signal
66 Hepatorenal Syndrome 13 19.2 19.2 signal
67 Haematoma Muscle 9 19.1 19.2 signal
68 Astigmatism 11 18.2 18.2 signal
69 Ulcer 115 18.1 18.3 signal
70 Bradycardia Neonatal 9 18.0 18.0 signal
71 Hypotonia Neonatal 11 18.0 18.0 signal
72 Intensive Care 10 17.9 18.0 signal
73 Coagulopathy 118 17.8 18.0 signal
74 Neuralgia 172 17.8 18.1 signal
75 Blood Test Abnormal 99 17.6 17.8 signal
76 Gout 126 17.6 17.8 signal
77 Dyslexia 8 17.5 17.5 signal
78 Escherichia Bacteraemia 16 17.3 17.3 signal
79 Speech Disorder Developmental 19 16.5 16.5 signal
80 Rhonchi 9 16.2 16.3 signal
81 Pancreatic Failure 11 16.1 16.1 signal
82 Peritoneal Haemorrhage 9 16.0 16.0 signal
83 End Stage Renal Disease 117 15.9 16.1 signal
84 International Normalised Ratio Increased 182 15.8 16.1 signal
85 Hypoglycaemia Neonatal 10 15.6 15.6 signal
86 Portal Hypertension 19 15.4 15.4 signal
87 Learning Disorder 15 15.4 15.4 signal
88 Pulmonary Function Test Decreased 27 15.3 15.4 signal
89 Prothrombin Time Prolonged 37 15.3 15.4 signal
90 Aspiration 66 15.2 15.3 signal
91 Systemic Candida 15 15.2 15.2 signal
92 Rales 35 15.1 15.1 signal
93 Hyponatraemia 335 14.9 15.5 signal
94 Jugular Vein Thrombosis 10 14.2 14.2 signal
95 Staphylococcus Test Positive 12 14.1 14.1 signal
96 Bilirubin Conjugated Increased 13 14.0 14.0 signal
97 Bronchiectasis 36 13.5 13.6 signal
98 Micturition Urgency 61 13.4 13.5 signal
99 International Normalised Ratio Fluctuation 11 13.1 13.1 signal
100 Hypercholesterolaemia 50 13.1 13.1 signal
101 Rubber Sensitivity 8 13.0 13.1 signal
102 Full Blood Count Abnormal 55 13.0 13.1 signal
103 Genital Herpes 8 13.0 13.0 signal
104 Toxic Epidermal Necrolysis 78 12.9 13.0 signal
105 Pancreatitis Chronic 12 12.7 12.8 signal
106 Language Disorder 11 12.7 12.7 signal
107 Retroperitoneal Haematoma 11 12.5 12.5 signal
108 Regurgitation 17 12.4 12.4 signal
109 Liver Transplant 18 12.4 12.4 signal
110 Acute Hepatic Failure 67 12.3 12.4 signal
111 Venoocclusive Liver Disease 24 12.2 12.2 signal
112 Hyperbilirubinaemia 49 11.9 11.9 signal
113 Vitamin B12 Deficiency 19 11.8 11.8 signal
114 Splenic Infarction 8 11.5 11.5 signal
115 Aplastic Anaemia 24 11.4 11.5 signal
116 Hyperlactacidaemia 12 11.4 11.4 signal
117 Kyphosis 8 11.3 11.3 signal
118 Sputum Discoloured 42 11.1 11.1 signal
119 Vascular Device Infection 20 11.1 11.1 signal
120 Transaminases Increased 98 11.0 11.1 signal
121 Intraventricular Haemorrhage 11 11.0 11.0 signal
122 Stress 315 10.9 11.3 signal
123 Calciphylaxis 8 10.9 10.9 signal
124 Neutropenic Colitis 9 10.9 10.9 signal
125 Sepsis 481 10.8 11.3 signal
126 Psychomotor Retardation 12 10.7 10.7 signal
127 Acute Lymphocytic Leukaemia Recurrent 11 10.6 10.6 signal
128 Sputum Increased 9 10.6 10.6 signal
129 Heparin-induced Thrombocytopenia 21 10.6 10.6 signal
130 Hypernatraemia 21 10.6 10.6 signal
131 Blood Cholesterol Increased 184 9.8 10.0 signal
132 Lung Consolidation 11 9.8 9.8 signal
133 Oligohydramnios 13 9.7 9.7 signal
134 Cholestasis 74 9.7 9.7 signal
135 Abdominal Distension 399 9.6 10.0 signal
136 Abdominal Tenderness 19 9.5 9.6 signal
137 Intra-abdominal Haemorrhage 9 9.4 9.4 signal
138 Disseminated Intravascular Coagulation 53 9.4 9.4 signal
139 Hepatic Encephalopathy 35 9.3 9.4 signal
140 Chronic Obstructive Pulmonary Disease 189 9.0 9.2 signal
141 Venoocclusive Disease 9 9.0 9.0 signal
142 Pulmonary Haemorrhage 28 8.9 9.0 signal
143 Liver Function Test Increased 75 8.8 8.8 signal
144 Multi-organ Failure 61 8.7 8.7 signal
145 Fine Motor Skill Dysfunction 10 8.7 8.7 signal
146 International Normalised Ratio Decreased 14 8.5 8.6 signal
147 Bacteraemia 40 8.5 8.5 signal
148 Exposure Via Breast Milk 13 8.3 8.3 signal
149 Foetal Growth Restriction 20 8.3 8.3 signal
150 Tumour Lysis Syndrome 28 8.0 8.0 signal
151 Hepatic Failure 96 7.9 8.0 signal
152 Pulseless Electrical Activity 13 7.8 7.8 signal
153 Haemoptysis 87 7.8 7.8 signal
154 Febrile Bone Marrow Aplasia 13 7.7 7.8 signal
155 Blood Bilirubin Increased 84 7.7 7.8 signal
156 General Physical Health Deterioration 356 7.7 8.0 signal
157 Enterococcal Infection 15 7.7 7.7 signal
158 Pneumonia Fungal 12 7.7 7.7 signal
159 Bacterial Sepsis 10 7.6 7.6 signal
160 Strabismus 9 7.6 7.6 signal
161 Potentiating Drug Interaction 10 7.6 7.6 signal
162 Psychomotor Skills Impaired 8 7.6 7.6 signal
163 Gastritis Erosive 14 7.5 7.5 signal
164 Sleep Disorder 209 7.4 7.6 signal
165 Abdominal Abscess 13 7.3 7.3 signal
166 Brain Death 9 7.2 7.2 signal
167 Joint Injury 62 7.2 7.3 signal
168 Urine Abnormality 13 7.2 7.2 signal
169 Talipes 9 7.2 7.2 signal
170 Blood Creatinine Decreased 9 7.2 7.2 signal
171 Obstructive Airways Disorder 32 7.1 7.2 signal
172 Immune Effector Cell-associated Neurotoxicity Syndrome 16 7.1 7.1 signal
173 Testicular Pain 9 7.1 7.1 signal
174 Behaviour Disorder 15 7.0 7.1 signal
175 Forced Expiratory Volume Decreased 8 7.0 7.0 signal
176 Dry Mouth 227 7.0 7.2 signal
177 Blood Albumin Decreased 22 6.9 6.9 signal
178 Lower Respiratory Tract Infection 126 6.9 7.0 signal
179 Acute Respiratory Distress Syndrome 49 6.9 6.9 signal
180 Low Birth Weight Baby 22 6.9 6.9 signal
181 Pulmonary Mass 41 6.9 6.9 signal
182 Hypoalbuminaemia 21 6.8 6.9 signal
183 Subdural Haematoma 39 6.8 6.8 signal
184 Thrombosis 218 6.7 6.9 signal
185 Atelectasis 26 6.7 6.7 signal
186 Haemodynamic Instability 20 6.6 6.7 signal
187 Pleural Effusion 162 6.6 6.7 signal
188 Aspartate Aminotransferase Increased 141 6.6 6.7 signal
189 Neutropenic Sepsis 19 6.6 6.6 signal
190 Malnutrition 29 6.5 6.5 signal
191 Pulmonary Embolism 248 6.5 6.6 signal
192 Jaundice 70 6.5 6.5 signal
193 Mouth Haemorrhage 19 6.5 6.5 signal
194 Escherichia Urinary Tract Infection 11 6.4 6.5 signal
195 Diabetes Mellitus 198 6.4 6.6 signal
196 Shock Haemorrhagic 21 6.4 6.5 signal
197 Faeces Hard 10 6.4 6.4 signal
198 Blood Alkaline Phosphatase Increased 64 6.4 6.5 signal
199 Autism Spectrum Disorder 14 6.4 6.4 signal
200 Dyslipidaemia 13 6.4 6.4 signal
201 Jaundice Cholestatic 9 6.3 6.3 signal
202 Bronchiolitis 9 6.3 6.3 signal
203 Neonatal Respiratory Distress Syndrome 9 6.3 6.3 signal
204 Pancreatitis Acute 56 6.3 6.3 signal
205 Acidosis 19 6.2 6.2 signal
206 Ileus Paralytic 11 6.2 6.2 signal
207 Septic Shock 107 6.2 6.2 signal
208 Oropharyngeal Discomfort 22 6.1 6.1 signal
209 Acute Respiratory Failure 47 6.1 6.1 signal
210 Blood Magnesium Decreased 21 6.1 6.1 signal
211 Immunosuppressant Drug Level Increased 8 6.0 6.1 signal
212 Wound Haemorrhage 9 6.0 6.0 signal
213 Staphylococcal Sepsis 12 6.0 6.0 signal
214 Sleep Disorder Due To A General Medical Condition 39 6.0 6.0 signal
215 Attention Deficit Hyperactivity Disorder 10 6.0 6.0 signal
216 Blood Creatinine Increased 157 6.0 6.1 signal
217 Hypovolaemia 14 6.0 6.0 signal
218 Splenomegaly 28 6.0 6.0 signal
219 Protein Total Decreased 9 6.0 6.0 signal
220 Injury Associated With Device 48 5.9 6.0 signal
221 Cerebral Haematoma 8 5.9 5.9 signal
222 Purpura 21 5.9 5.9 signal
223 Hypoxia 83 5.9 5.9 signal
224 Cytokine Release Syndrome 45 5.9 5.9 signal
225 Cardiovascular Disorder 60 5.8 5.9 signal
226 Hepatic Fibrosis 8 5.8 5.8 signal
227 Hepatitis Acute 15 5.8 5.8 signal
228 Staphylococcal Bacteraemia 10 5.7 5.8 signal
229 International Normalised Ratio Abnormal 8 5.7 5.7 signal
230 Enterocolitis 13 5.7 5.7 signal
231 Metabolic Acidosis 72 5.7 5.7 signal
232 Blood Creatine Increased 10 5.6 5.6 signal
233 Fibrin D Dimer Increased 8 5.6 5.6 signal
234 Intentional Product Misuse 195 5.6 5.7 signal
235 Azotaemia 9 5.6 5.6 signal
236 Swelling 207 5.5 5.6 signal
237 Blood Phosphorus Decreased 8 5.5 5.5 signal
238 Blood Urea Increased 37 5.5 5.5 signal
239 Haematoma 57 5.5 5.5 signal
240 Intestinal Ischaemia 12 5.5 5.5 signal
241 Productive Cough 103 5.4 5.5 signal
242 Autoimmune Hepatitis 15 5.4 5.4 signal
243 Ammonia Increased 11 5.4 5.4 signal
244 Incorrect Drug Administration Rate 9 5.3 5.3 signal
245 Hepatomegaly 21 5.3 5.3 signal
246 Small Intestinal Obstruction 26 5.3 5.3 signal
247 Systemic Inflammatory Response Syndrome 8 5.2 5.2 signal
248 Posterior Reversible Encephalopathy Syndrome 20 5.2 5.2 signal
249 Gastrointestinal Pain 23 5.2 5.2 signal
250 Pulse Absent 10 5.2 5.2 signal
251 Conjunctival Haemorrhage 8 5.2 5.2 signal
252 Tachypnoea 28 5.1 5.2 signal
253 Diverticulum Intestinal 9 5.1 5.1 signal
254 Post Procedural Haemorrhage 24 5.1 5.1 signal
255 Constipation 443 5.1 5.3 signal
256 Apnoea 16 5.1 5.1 signal
257 Ecchymosis 14 5.1 5.1 signal
258 Torsade De Pointes 16 5.1 5.1 signal
259 Flank Pain 19 5.1 5.1 signal
260 Anaemia 384 5.0 5.2 signal
261 Pseudomonas Infection 17 5.0 5.0 signal
262 Abdominal Pain 462 4.9 5.2 signal
263 Hepatic Cirrhosis 37 4.9 4.9 signal
264 Febrile Neutropenia 131 4.9 5.0 signal
265 Dermatitis Exfoliative 10 4.9 4.9 signal
266 Hepatocellular Injury 28 4.9 4.9 signal
267 Inguinal Hernia 12 4.9 4.9 signal
268 Dysgraphia 13 4.9 4.9 signal
269 Iron Deficiency Anaemia 18 4.9 4.9 signal
270 Subarachnoid Haemorrhage 20 4.9 4.9 signal
271 Ear Disorder 9 4.9 4.9 signal
272 Vitamin D Deficiency 19 4.9 4.9 signal
273 Haemophagocytic Lymphohistiocytosis 14 4.8 4.8 signal
274 Coronary Artery Disease 59 4.8 4.8 signal
275 Encephalopathy 47 4.8 4.8 signal
276 Failure To Thrive 10 4.8 4.8 signal
277 Sensitivity To Weather Change 10 4.8 4.8 signal
278 Atrial Septal Defect 16 4.7 4.7 signal
279 Upper Gastrointestinal Haemorrhage 32 4.7 4.7 signal
280 Hypokalaemia 87 4.7 4.8 signal
281 Hypovolaemic Shock 9 4.7 4.7 signal
282 Clostridium Difficile Colitis 20 4.7 4.7 signal
283 Hypervolaemia 9 4.7 4.7 signal
284 Drug Reaction With Eosinophilia And Systemic Symptoms 47 4.6 4.6 signal
285 Urine Output Decreased 16 4.5 4.6 signal
286 Fluid Intake Reduced 9 4.5 4.5 signal
287 Thrombocytopenia 203 4.5 4.6 signal
288 Bronchopulmonary Aspergillosis 14 4.5 4.5 signal
289 Haemolysis 14 4.5 4.5 signal
290 Gamma-glutamyltransferase Increased 40 4.5 4.5 signal
291 Infusion Site Pain 23 4.5 4.5 signal
292 Intracranial Pressure Increased 10 4.5 4.5 signal
293 Cholangitis 11 4.4 4.4 signal
294 Supraventricular Tachycardia 17 4.4 4.4 signal
295 Drug Intolerance 171 4.4 4.5 signal
296 Respiratory Failure 129 4.4 4.5 signal
297 Epstein-barr Virus Infection 11 4.4 4.4 signal
298 Covid-19 Pneumonia 21 4.4 4.4 signal
299 Liver Disorder 78 4.4 4.4 signal
300 Upper Respiratory Tract Infection 81 4.4 4.4 signal
301 Cerebral Ischaemia 9 4.3 4.3 signal
302 Skin Necrosis 9 4.3 4.3 signal
303 Parosmia 13 4.3 4.3 signal
304 Premature Baby 52 4.3 4.3 signal
305 Decubitus Ulcer 14 4.3 4.3 signal
306 Nephrogenic Anaemia 8 4.3 4.3 signal
307 Feeding Disorder 34 4.2 4.3 signal
308 Spinal Fracture 34 4.2 4.3 signal
309 Anal Abscess 9 4.2 4.2 signal
310 Embolism 14 4.2 4.2 signal
311 Pulmonary Fibrosis 32 4.2 4.2 signal
312 Wheezing 99 4.2 4.2 signal
313 Haematemesis 42 4.1 4.1 signal
314 Nocturia 20 4.1 4.1 signal
315 Foetal Exposure During Pregnancy 134 4.1 4.2 signal
316 Aphagia 8 4.1 4.1 signal
317 Colitis Ischaemic 11 4.1 4.1 signal
318 Staphylococcal Infection 54 4.1 4.1 signal
319 Transient Ischaemic Attack 55 4.0 4.1 signal
320 Sinus Tachycardia 23 4.0 4.0 signal
321 Toxic Encephalopathy 8 4.0 4.0 signal
322 General Physical Condition Abnormal 11 4.0 4.0 signal
323 Hepatic Enzyme Abnormal 8 4.0 4.0 signal
324 Renal Failure Acute 69 4.0 4.0 signal
325 Haemorrhage Intracranial 24 4.0 4.0 signal
326 Musculoskeletal Stiffness 140 4.0 4.0 signal
327 Blood Calcium Decreased 18 4.0 4.0 signal
328 Drug-induced Liver Injury 49 4.0 4.0 signal
329 Epistaxis 119 4.0 4.0 signal
330 Lipase Increased 12 3.9 3.9 signal
331 Oedema Peripheral 192 3.9 4.0 signal
332 Aphthous Ulcer 12 3.9 3.9 signal
333 Respiratory Distress 43 3.9 3.9 signal
334 Maternal Drugs Affecting Foetus 12 3.8 3.9 signal
335 Somnolence 310 3.8 3.9 signal
336 Developmental Delay 14 3.8 3.8 signal
337 Secretion Discharge 19 3.8 3.8 signal
338 Lung Disorder 75 3.8 3.8 signal
339 Foot Deformity 17 3.8 3.8 signal
340 Liver Injury 37 3.8 3.8 signal
341 Pancytopenia 85 3.8 3.8 signal
342 Eructation 29 3.8 3.8 signal
343 Mental Status Changes 42 3.8 3.8 signal
344 Body Temperature Decreased 15 3.8 3.8 signal
345 Hepatic Steatosis 28 3.7 3.8 signal
346 Cardiac Failure Acute 10 3.7 3.7 signal
347 Atrial Flutter 12 3.7 3.7 signal
348 Eating Disorder 32 3.7 3.7 signal
349 Blood Disorder 12 3.7 3.7 signal
350 Mucosal Inflammation 39 3.7 3.7 signal
351 Cardiac Murmur 13 3.7 3.7 signal
352 Fluid Overload 22 3.7 3.7 signal
353 Motor Dysfunction 15 3.7 3.7 signal
354 Oxygen Saturation Decreased 82 3.7 3.7 signal
355 Eye Discharge 15 3.7 3.7 signal
356 Escherichia Infection 12 3.7 3.7 signal
357 Respiration Abnormal 10 3.6 3.6 signal
358 Haemoglobin Decreased 150 3.6 3.7 signal
359 Dizziness Postural 14 3.6 3.6 signal
360 Haematocrit Decreased 29 3.6 3.6 signal
361 Sciatica 23 3.6 3.6 signal
362 Large Intestine Perforation 10 3.6 3.6 signal
363 Candida Infection 24 3.6 3.6 signal
364 Pulmonary Alveolar Haemorrhage 8 3.6 3.6 signal
365 Device Related Infection 22 3.5 3.6 signal
366 Renal Tubular Necrosis 14 3.5 3.5 signal
367 Acute Generalised Exanthematous Pustulosis 11 3.5 3.5 signal
368 Alanine Aminotransferase Increased 87 3.5 3.6 signal
369 Mitral Valve Incompetence 16 3.5 3.5 signal
370 Acute Myeloid Leukaemia 22 3.5 3.5 signal
371 Post Procedural Complication 27 3.5 3.5 signal
372 Multiple Allergies 11 3.5 3.5 signal
373 Gastrooesophageal Reflux Disease 112 3.5 3.5 signal
374 Hypotonia 14 3.5 3.5 signal
375 Electrocardiogram Abnormal 11 3.5 3.5 signal
376 Drug Hypersensitivity 271 3.5 3.6 signal
377 Electrolyte Imbalance 16 3.5 3.5 signal
378 Diverticulum 10 3.5 3.5 signal
379 Panic Reaction 10 3.5 3.5 signal
380 Oral Candidiasis 18 3.4 3.4 signal
381 Leukocytosis 25 3.4 3.4 signal
382 Gingival Pain 11 3.4 3.4 signal
383 Generalised Oedema 17 3.4 3.4 signal
384 Blood Lactate Dehydrogenase Increased 22 3.4 3.4 signal
385 Metabolic Disorder 8 3.4 3.4 signal
386 Transplant Rejection 11 3.4 3.4 signal
387 Hypertriglyceridaemia 8 3.4 3.4 signal
388 Pulmonary Oedema 61 3.4 3.4 signal
389 Acute Kidney Injury 206 3.4 3.4 signal
390 Condition Aggravated 408 3.4 3.5 signal
391 Lung Infiltration 12 3.4 3.4 signal
392 Brain Oedema 17 3.4 3.4 signal
393 Labelled Drug-drug Interaction Medication Error 12 3.3 3.3 signal
394 Thrombotic Microangiopathy 13 3.3 3.3 signal
395 Faeces Discoloured 29 3.3 3.3 signal
396 Transfusion 14 3.3 3.3 signal
397 Ulcer Haemorrhage 9 3.3 3.3 signal
398 Pneumothorax 21 3.3 3.3 signal
399 Hypocalcaemia 25 3.3 3.3 signal
400 Dermatitis Acneiform 8 3.3 3.3 signal
401 Melaena 29 3.3 3.3 signal
402 Onychoclasis 9 3.3 3.3 signal
403 Dyspnoea Exertional 49 3.2 3.3 signal
404 Joint Effusion 9 3.2 3.2 signal
405 Cerebral Haemorrhage 46 3.2 3.2 signal
406 Cardio-respiratory Arrest 54 3.2 3.2 signal
407 Hypothermia 13 3.2 3.2 signal
408 Pyelonephritis 11 3.2 3.2 signal
409 Muscle Atrophy 16 3.2 3.2 signal
410 Anuria 11 3.2 3.2 signal
411 Toothache 23 3.2 3.2 signal
412 Deep Vein Thrombosis 83 3.2 3.2 signal
413 Cytopenia 15 3.1 3.1 signal
414 Ventricular Extrasystoles 13 3.1 3.1 signal
415 Intraocular Pressure Increased 16 3.1 3.1 signal
416 Clostridium Difficile Infection 27 3.1 3.1 signal
417 Tenderness 13 3.1 3.1 signal
418 Brain Fog 18 3.1 3.1 signal
419 Appetite Disorder 8 3.1 3.1 signal
420 Decreased Immune Responsiveness 12 3.1 3.1 signal
421 Gastrointestinal Disorder 108 3.0 3.1 signal
422 Hepatotoxicity 27 3.0 3.0 signal
423 Vomiting 571 3.0 3.2 signal
424 Gastroenteritis Viral 22 3.0 3.0 signal
425 Gastric Ulcer 23 3.0 3.0 signal
426 Ventricular Tachycardia 20 3.0 3.0 signal
427 Infusion Site Erythema 10 3.0 3.0 signal
428 Hydronephrosis 9 3.0 3.0 signal
429 Lung Infection 19 3.0 3.0 signal
430 Cyanosis 19 3.0 3.0 signal
431 Tachycardia 107 3.0 3.0 signal
432 Seasonal Allergy 17 3.0 3.0 signal
433 Joint Range Of Motion Decreased 16 3.0 3.0 signal
434 Rectal Haemorrhage 51 2.9 3.0 signal
435 Asthma 132 2.9 3.0 signal
436 Grand Mal Convulsion 11 2.9 2.9 signal
437 Viral Infection 39 2.9 2.9 signal
438 Hypotension 234 2.9 3.0 signal
439 Vitamin D Decreased 10 2.9 2.9 signal
440 Bradycardia 62 2.9 2.9 signal
441 Procedural Complication 9 2.9 2.9 signal
442 Gastrointestinal Haemorrhage 98 2.9 2.9 signal
443 Platelet Count Decreased 124 2.9 2.9 signal
444 Intestinal Perforation 13 2.9 2.9 signal
445 Respiratory Syncytial Virus Infection 10 2.9 2.9 signal
446 Renal Failure Chronic 9 2.9 2.9 signal
447 Infection 166 2.9 2.9 signal
448 Chromaturia 26 2.9 2.9 signal
449 Pulmonary Hypertension 24 2.9 2.9 signal
450 Dermatitis Contact 13 2.8 2.9 signal
451 Cytomegalovirus Infection 19 2.8 2.8 signal
452 Colitis 43 2.8 2.8 signal
453 Shock 26 2.8 2.8 signal
454 Duodenal Ulcer 8 2.8 2.8 signal
455 Atrial Fibrillation 110 2.8 2.8 signal
456 Bone Marrow Failure 23 2.8 2.8 signal
457 Sudden Death 12 2.8 2.8 signal
458 Gastric Haemorrhage 13 2.8 2.8 signal
459 Loss Of Personal Independence In Daily Activities 53 2.8 2.8 signal
460 Osteopenia 17 2.8 2.8 signal
461 Foot Fracture 21 2.7 2.8 signal
462 Abnormal Faeces 9 2.7 2.7 signal
463 Exostosis 10 2.7 2.7 signal
464 Cystitis 35 2.7 2.7 signal
465 Pneumonia Bacterial 10 2.7 2.7 signal
466 Ear Infection 29 2.7 2.7 signal
467 Increased Tendency To Bruise 10 2.7 2.7 signal
468 Rash Maculo-papular 24 2.7 2.7 signal
469 Hypomagnesaemia 15 2.7 2.7 signal
470 Haematuria 37 2.7 2.7 signal
471 Lower Gastrointestinal Haemorrhage 8 2.7 2.7 signal
472 Tooth Abscess 11 2.7 2.7 signal
473 Body Temperature Increased 22 2.7 2.7 signal
474 Spinal Compression Fracture 9 2.7 2.7 signal
475 Abscess 17 2.7 2.7 signal
476 Poor Venous Access 11 2.7 2.7 signal
477 Hepatic Cytolysis 13 2.6 2.6 signal
478 Tooth Infection 14 2.6 2.6 signal
479 Haemodialysis 9 2.6 2.6 signal
480 Hyperthermia 8 2.6 2.6 signal
481 Tendon Pain 8 2.6 2.6 signal
482 Dialysis 15 2.6 2.6 signal
483 Spinal Disorder 10 2.6 2.6 signal
484 Pyrexia 364 2.6 2.7 signal
485 Hypertension 222 2.6 2.6 signal
486 Musculoskeletal Discomfort 18 2.6 2.6 signal
487 Myopathy 9 2.6 2.6 signal
488 Cholelithiasis 34 2.6 2.6 signal
489 Respiratory Disorder 31 2.6 2.6 signal
490 Oral Herpes 20 2.6 2.6 signal
491 Lethargy 59 2.6 2.6 signal
492 Hepatic Function Abnormal 38 2.6 2.6 signal
493 Pain In Jaw 29 2.5 2.5 signal
494 Spinal Osteoarthritis 9 2.5 2.5 signal
495 Skin Laceration 11 2.5 2.5 signal
496 Immunodeficiency 15 2.5 2.5 signal
497 Lymphocyte Count Decreased 18 2.5 2.5 signal
498 Tubulointerstitial Nephritis 19 2.5 2.5 signal
499 Acute Myocardial Infarction 30 2.5 2.5 signal
500 Tricuspid Valve Incompetence 8 2.5 2.5 signal
501 Pneumonia 327 2.5 2.6 signal
502 Proteinuria 19 2.5 2.5 signal
503 Macular Degeneration 12 2.5 2.5 signal
504 Renal Cyst 8 2.5 2.5 signal
505 Feeling Cold 28 2.5 2.5 signal
506 Drug Interaction 159 2.5 2.5 signal
507 Pericardial Effusion 23 2.5 2.5 signal
508 Mouth Ulceration 21 2.5 2.5 signal
509 Dehydration 133 2.5 2.5 signal
510 Platelet Count Increased 13 2.5 2.5 signal
511 Rhinitis 8 2.5 2.5 signal
512 Product Use In Unapproved Indication 240 2.4 2.5 signal
513 Oral Pain 22 2.4 2.4 signal
514 Respiratory Depression 12 2.4 2.4 signal
515 Dysuria 36 2.4 2.4 signal
516 Hyperkalaemia 34 2.4 2.4 signal
517 Agranulocytosis 18 2.4 2.4 signal
518 Hypercalcaemia 12 2.4 2.4 signal
519 Status Epilepticus 11 2.4 2.4 signal
520 Dyspnoea 544 2.4 2.5 signal
521 Intestinal Obstruction 36 2.4 2.4 signal
522 Live Birth 8 2.4 2.4 signal
523 Gastroenteritis 14 2.4 2.4 signal
524 Blood Triglycerides Increased 17 2.4 2.4 signal
525 Drug Exposure During Pregnancy 33 2.4 2.4 signal
526 Arteriosclerosis 9 2.4 2.4 signal
527 Gingival Bleeding 13 2.4 2.4 signal
528 Eye Pain 52 2.3 2.4 signal
529 Autoimmune Disorder 9 2.3 2.3 signal
530 Hepatitis 24 2.3 2.3 signal
531 Mydriasis 12 2.3 2.3 signal
532 Hyperglycaemia 34 2.3 2.3 signal
533 Poor Quality Sleep 20 2.3 2.3 signal
534 Sinus Bradycardia 9 2.3 2.3 signal
535 Neck Pain 52 2.3 2.3 signal
536 Respiratory Tract Infection 24 2.3 2.3 signal
537 Infusion Related Reaction 61 2.3 2.3 signal
538 Ocular Discomfort 10 2.3 2.3 signal
539 Tremor 153 2.3 2.3 signal
540 Metastases To Bone 15 2.3 2.3 signal
541 Oesophagitis 10 2.3 2.3 signal
542 Ligament Sprain 9 2.3 2.3 signal
543 Cough 255 2.3 2.3 signal
544 Photophobia 17 2.3 2.3 signal
545 Bronchospasm 13 2.3 2.3 signal
546 Sinus Disorder 18 2.3 2.3 signal
547 Dyspepsia 89 2.3 2.3 signal
548 Hypoglycaemia 44 2.3 2.3 signal
549 Dental Caries 10 2.3 2.3 signal
550 Lactic Acidosis 29 2.2 2.3 signal
551 Haemorrhage 94 2.2 2.3 signal
552 Renal Failure 120 2.2 2.2 signal
553 Gastrointestinal Infection 8 2.2 2.2 signal
554 Tooth Disorder 20 2.2 2.2 signal
555 Unresponsive To Stimuli 23 2.2 2.2 signal
556 Ileus 11 2.2 2.2 signal
557 Cardiac Arrest 74 2.2 2.2 signal
558 Myositis 8 2.2 2.2 signal
559 Toxic Skin Eruption 9 2.2 2.2 signal
560 Blood Creatine Phosphokinase Increased 26 2.2 2.2 signal
561 Pneumonitis 24 2.2 2.2 signal
562 Depressed Level Of Consciousness 35 2.2 2.2 signal
563 Ear Discomfort 9 2.2 2.2 signal
564 Neutrophil Count Increased 9 2.2 2.2 signal
565 Premature Delivery 14 2.2 2.2 signal
566 Cellulitis 44 2.2 2.2 signal
567 Urinary Retention 29 2.2 2.2 signal
568 Haemorrhoids 17 2.2 2.2 signal
569 Sensory Disturbance 14 2.2 2.2 signal
570 Petechiae 9 2.2 2.2 signal
571 Weight Fluctuation 9 2.1 2.1 signal
572 Nausea 679 2.1 2.2 signal
573 Renal Impairment 72 2.1 2.2 signal
574 Neutropenia 116 2.1 2.1 signal
575 Frequent Bowel Movements 23 2.1 2.1 signal
576 Liver Function Test Abnormal 25 2.1 2.1 signal
577 Diarrhoea Haemorrhagic 8 2.1 2.1 no signal
578 Bone Pain 50 2.1 2.1 signal
579 Heart Rate Decreased 30 2.1 2.1 signal
580 White Blood Cell Count Decreased 92 2.1 2.1 signal
581 Weight Decreased 236 2.1 2.1 signal
582 Pallor 23 2.1 2.1 signal
583 Thirst 15 2.1 2.1 signal
584 Decreased Activity 9 2.1 2.1 signal
585 Dysphonia 49 2.1 2.1 signal
586 Red Blood Cell Count Decreased 24 2.1 2.1 signal
587 Sleep Apnoea Syndrome 16 2.1 2.1 signal
588 Tendonitis 13 2.1 2.1 signal
589 Adrenal Insufficiency 10 2.1 2.1 signal
590 Blood Potassium Decreased 25 2.1 2.1 signal
591 Osteomyelitis 15 2.1 2.1 signal
592 Aphasia 25 2.1 2.1 signal
593 Discomfort 50 2.1 2.1 signal
594 Anaphylactic Reaction 45 2.0 2.0 signal
595 Blood Pressure Systolic Increased 16 2.0 2.0 signal
596 Scar 14 2.0 2.0 signal
597 Obesity 13 2.0 2.0 signal
598 Neutrophil Count Decreased 33 2.0 2.0 signal
599 Off Label Use 705 2.0 2.1 signal
600 Delirium 28 2.0 2.0 signal
601 Nephropathy Toxic 9 2.0 2.0 no signal
602 Insurance Issue 12 2.0 2.0 signal
603 Electrocardiogram Qt Prolonged 29 2.0 2.0 signal
604 Bladder Disorder 8 2.0 2.0 no signal
605 Contusion 77 2.0 2.0 no signal
606 Gastritis 21 2.0 2.0 no signal
607 Inflammation 41 2.0 2.0 no signal
608 Haematochezia 44 2.0 2.0 no signal
609 Head Discomfort 14 2.0 2.0 no signal
610 Respiratory Arrest 22 2.0 2.0 no signal
611 Altered State Of Consciousness 17 2.0 2.0 no signal
612 Hypophagia 20 2.0 2.0 no signal
613 Sluggishness 8 2.0 2.0 no signal
614 Asthenia 296 2.0 2.0 no signal
615 Feeling Jittery 15 2.0 2.0 no signal
616 Myocardial Ischaemia 9 2.0 2.0 no signal
617 Temperature Intolerance 8 1.9 1.9 no signal
618 Coordination Abnormal 11 1.9 1.9 no signal
619 Sinusitis 80 1.9 1.9 no signal
620 Cerebral Infarction 19 1.9 1.9 no signal
621 Rhinorrhoea 50 1.9 1.9 no signal
622 Musculoskeletal Chest Pain 12 1.9 1.9 no signal
623 Femur Fracture 24 1.9 1.9 no signal
624 Neuropathy Peripheral 73 1.9 1.9 no signal
625 Ear Pain 15 1.9 1.9 no signal
626 Hiatus Hernia 10 1.9 1.9 no signal
627 Heart Rate Increased 76 1.9 1.9 no signal
628 Caesarean Section 9 1.9 1.9 no signal
629 Anorexia 10 1.9 1.9 no signal
630 Kidney Infection 15 1.9 1.9 no signal
631 Stevens-johnson Syndrome 17 1.9 1.9 no signal
632 Hemiparesis 13 1.9 1.9 no signal
633 Pneumonia Aspiration 19 1.9 1.9 no signal
634 Skin Haemorrhage 11 1.9 1.9 no signal
635 Joint Stiffness 20 1.9 1.9 no signal
636 Lymphadenopathy 27 1.9 1.9 no signal
637 Bone Disorder 14 1.9 1.9 no signal
638 Sneezing 17 1.9 1.9 no signal
639 Immune System Disorder 10 1.9 1.9 no signal
640 Myelodysplastic Syndrome 11 1.9 1.9 no signal
641 Decreased Appetite 176 1.9 1.9 no signal
642 Nerve Compression 7 1.9 1.9 no signal
643 Cholecystitis 9 1.9 1.9 no signal
644 Eczema 38 1.9 1.9 no signal
645 Incontinence 8 1.9 1.9 no signal
646 Muscle Rigidity 9 1.9 1.9 no signal
647 Osteoporosis 31 1.9 1.9 no signal
648 Retching 16 1.9 1.9 no signal
649 Intervertebral Disc Degeneration 7 1.9 1.9 no signal
650 Hepatic Enzyme Increased 51 1.9 1.9 no signal
651 Maternal Exposure During Pregnancy 66 1.9 1.9 no signal
652 Neurotoxicity 13 1.9 1.9 no signal
653 Heart Rate Irregular 17 1.9 1.9 no signal
654 Visual Acuity Reduced 25 1.9 1.9 no signal
655 Presyncope 18 1.8 1.9 no signal
656 Nephrolithiasis 34 1.8 1.9 no signal
657 Flatulence 42 1.8 1.8 no signal
658 Plasma Cell Myeloma 29 1.8 1.8 no signal
659 Metastases To Liver 13 1.8 1.8 no signal
660 Chills 87 1.8 1.9 no signal
661 Pharyngitis Streptococcal 8 1.8 1.8 no signal
662 Cold Sweat 13 1.8 1.8 no signal
663 Generalised Tonic-clonic Seizure 12 1.8 1.8 no signal
664 Pulmonary Thrombosis 8 1.8 1.8 no signal
665 Intentional Dose Omission 20 1.8 1.8 no signal
666 Osteoarthritis 31 1.8 1.8 no signal
667 Myalgia 124 1.8 1.8 no signal
668 Urinary Tract Infection 124 1.8 1.8 no signal
669 Cardiac Failure Congestive 59 1.8 1.8 no signal
670 White Blood Cell Count Increased 28 1.8 1.8 no signal
671 Fatigue 564 1.8 1.9 no signal
672 Peripheral Coldness 10 1.8 1.8 no signal
673 Drug Level Increased 12 1.8 1.8 no signal
674 Peritonitis 15 1.8 1.8 no signal
675 Oropharyngeal Pain 67 1.8 1.8 no signal
676 Oedema 39 1.8 1.8 no signal
677 Tinnitus 33 1.8 1.8 no signal
678 Night Sweats 23 1.8 1.8 no signal
679 Restless Legs Syndrome 13 1.8 1.8 no signal
680 Coma 34 1.8 1.8 no signal
681 Diarrhoea 458 1.8 1.8 no signal
682 Blood Pressure Decreased 47 1.8 1.8 no signal
683 Product Dose Omission In Error 19 1.8 1.8 no signal
684 Therapeutic Product Effect Incomplete 50 1.8 1.8 no signal
685 Speech Disorder 37 1.8 1.8 no signal
686 Confusional State 114 1.8 1.8 no signal
687 Cholecystectomy 8 1.8 1.8 no signal
688 Drug Ineffective For Unapproved Indication 39 1.7 1.7 no signal
689 Skin Lesion 19 1.7 1.7 no signal
690 Influenza 78 1.7 1.7 no signal
691 Skin Ulcer 18 1.7 1.7 no signal
692 Gait Inability 23 1.7 1.7 no signal
693 Injection Site Induration 9 1.7 1.7 no signal
694 Agitation 51 1.7 1.7 no signal
695 Blood Sodium Decreased 13 1.7 1.7 no signal
696 Hypothyroidism 22 1.7 1.7 no signal
697 Covid-19 122 1.7 1.7 no signal
698 Rash Macular 24 1.7 1.7 no signal
699 Apathy 10 1.7 1.7 no signal
700 Mental Disorder 30 1.7 1.7 no signal
701 Nasal Congestion 40 1.7 1.7 no signal
702 Musculoskeletal Pain 36 1.7 1.7 no signal
703 Blood Iron Decreased 8 1.7 1.7 no signal
704 Blister 38 1.7 1.7 no signal
705 Arthralgia 281 1.7 1.7 no signal
706 Blood Potassium Increased 11 1.7 1.7 no signal
707 Neuroleptic Malignant Syndrome 8 1.7 1.7 no signal
708 Abdominal Pain Upper 138 1.7 1.7 no signal
709 Wrist Fracture 8 1.7 1.7 no signal
710 Nervousness 35 1.7 1.7 no signal
711 Blood Pressure Increased 102 1.7 1.7 no signal
712 Disturbance In Attention 36 1.7 1.7 no signal
713 Depressed Mood 35 1.7 1.7 no signal
714 Bursitis 8 1.6 1.6 no signal
715 Memory Impairment 91 1.6 1.7 no signal
716 Nasopharyngitis 122 1.6 1.7 no signal
717 Palpitations 77 1.6 1.6 no signal
718 Blood Pressure Abnormal 13 1.6 1.6 no signal
719 Breast Cancer Metastatic 7 1.6 1.6 no signal
720 Feeling Hot 40 1.6 1.6 no signal
721 Muscle Twitching 15 1.6 1.6 no signal
722 Rhabdomyolysis 27 1.6 1.6 no signal
723 Chest Discomfort 66 1.6 1.6 no signal
724 Headache 405 1.6 1.6 no signal
725 No Therapeutic Response 8 1.6 1.6 no signal
726 Limb Discomfort 20 1.6 1.6 no signal
727 Middle Insomnia 12 1.6 1.6 no signal
728 Cardiomegaly 8 1.6 1.6 no signal
729 Wound Infection 7 1.6 1.6 no signal
730 Pain In Extremity 190 1.6 1.6 no signal
731 Stomatitis 39 1.6 1.6 no signal
732 Ejection Fraction Decreased 10 1.6 1.6 no signal
733 Pharyngitis 8 1.6 1.6 no signal
734 Urinary Incontinence 19 1.6 1.6 no signal
735 Nephropathy 6 1.6 1.6 no signal
736 Muscle Spasms 117 1.6 1.6 no signal
737 Inappropriate Schedule Of Product Administration 112 1.6 1.6 no signal
738 Peripheral Swelling 97 1.6 1.6 no signal
739 Abdominal Pain Lower 16 1.6 1.6 no signal
740 Fungal Infection 21 1.6 1.6 no signal
741 Eosinophilia 11 1.6 1.6 no signal
742 Pharyngeal Swelling 6 1.6 1.6 no signal
743 Paraesthesia Oral 9 1.6 1.6 no signal
744 Pollakiuria 26 1.6 1.6 no signal
745 Local Swelling 11 1.5 1.5 no signal
746 Fistula 7 1.5 1.5 no signal
747 Interstitial Lung Disease 30 1.5 1.5 no signal
748 Movement Disorder 20 1.5 1.5 no signal
749 Vitreous Floaters 6 1.5 1.5 no signal
750 Gallbladder Disorder 11 1.5 1.5 no signal
751 Emotional Disorder 19 1.5 1.5 no signal
752 Internal Haemorrhage 7 1.5 1.5 no signal
753 Laboratory Test Abnormal 18 1.5 1.5 no signal
754 Skin Discolouration 28 1.5 1.5 no signal
755 Bedridden 8 1.5 1.5 no signal
756 Chest Pain 113 1.5 1.5 no signal
757 Product Substitution Issue 35 1.5 1.5 no signal
758 Weight Increased 135 1.5 1.5 no signal
759 Complication Associated With Device 8 1.5 1.5 no signal
760 Bronchitis 45 1.5 1.5 no signal
761 Product Dose Omission Issue 171 1.5 1.5 no signal
762 Back Pain 139 1.5 1.5 no signal
763 Brain Injury 6 1.5 1.5 no signal
764 Spinal Pain 7 1.5 1.5 no signal
765 Alopecia 117 1.5 1.5 no signal
766 Disease Progression 70 1.5 1.5 no signal
767 Hair Texture Abnormal 8 1.5 1.5 no signal
768 Insomnia 158 1.5 1.5 no signal
769 Face Oedema 10 1.5 1.5 no signal
770 Myoclonus 7 1.5 1.5 no signal
771 Feeling Abnormal 141 1.5 1.5 no signal
772 Pancreatitis 31 1.5 1.5 no signal
773 Increased Appetite 11 1.5 1.5 no signal
774 Burning Sensation 41 1.5 1.5 no signal
775 Circulatory Collapse 10 1.5 1.5 no signal
776 Blood Pressure Fluctuation 14 1.4 1.4 no signal
777 Irritability 35 1.4 1.4 no signal
778 Ankle Fracture 9 1.4 1.4 no signal
779 Cognitive Disorder 27 1.4 1.4 no signal
780 Disorientation 23 1.4 1.4 no signal
781 Blood Urine Present 11 1.4 1.4 no signal
782 Mental Impairment 14 1.4 1.4 no signal
783 Sedation 15 1.4 1.4 no signal
784 Device Occlusion 8 1.4 1.4 no signal
785 Gynaecomastia 18 1.4 1.4 no signal
786 Nervous System Disorder 18 1.4 1.4 no signal
787 Deafness 15 1.4 1.4 no signal
788 Abdominal Discomfort 95 1.4 1.4 no signal
789 Renal Pain 6 1.4 1.4 no signal
790 Muscular Weakness 64 1.4 1.4 no signal
791 Exposure During Pregnancy 35 1.4 1.4 no signal
792 Hyperhidrosis 72 1.4 1.4 no signal
793 Muscle Tightness 9 1.4 1.4 no signal
794 Throat Tightness 15 1.4 1.4 no signal
795 Body Height Decreased 6 1.4 1.4 no signal
796 Balance Disorder 48 1.4 1.4 no signal
797 Limb Injury 15 1.4 1.4 no signal
798 Product Physical Issue 11 1.4 1.4 no signal
799 Fluid Retention 28 1.4 1.4 no signal
800 C-reactive Protein Increased 20 1.4 1.4 no signal
801 Syncope 55 1.4 1.4 no signal
802 Pulmonary Arterial Hypertension 8 1.4 1.4 no signal
803 Impaired Gastric Emptying 7 1.4 1.4 no signal
804 Impaired Healing 18 1.4 1.4 no signal
805 Intervertebral Disc Protrusion 12 1.4 1.4 no signal
806 Hypoaesthesia 82 1.4 1.4 no signal
807 Photosensitivity Reaction 9 1.4 1.4 no signal
808 Blood Glucose Fluctuation 6 1.4 1.4 no signal
809 Cardiomyopathy 8 1.3 1.3 no signal
810 Blood Glucose Abnormal 10 1.3 1.3 no signal
811 Flushing 55 1.3 1.3 no signal
812 Head Injury 17 1.3 1.3 no signal
813 Pain 330 1.3 1.3 no signal
814 Eye Infection 6 1.3 1.3 no signal
815 Drug Withdrawal Syndrome Neonatal 8 1.3 1.3 no signal
816 Arthritis 42 1.3 1.3 no signal
817 Dermatitis 11 1.3 1.3 no signal
818 Rebound Effect 6 1.3 1.3 no signal
819 Anhedonia 14 1.3 1.3 no signal
820 Vertigo 32 1.3 1.3 no signal
821 Hallucination, Visual 11 1.3 1.3 no signal
822 Laceration 5 1.3 1.3 no signal
823 Eye Haemorrhage 7 1.3 1.3 no signal
824 Cardiac Failure 42 1.3 1.3 no signal
825 Quality Of Life Decreased 7 1.3 1.3 no signal
826 Paraesthesia 82 1.3 1.3 no signal
827 Metastases To Lung 6 1.3 1.3 no signal
828 Surgery 30 1.3 1.3 no signal
829 Sinus Congestion 7 1.3 1.3 no signal
830 Throat Irritation 23 1.3 1.3 no signal
831 Dysstasia 15 1.3 1.3 no signal
832 Skin Disorder 17 1.3 1.3 no signal
833 Malaise 224 1.3 1.3 no signal
834 Diabetes Mellitus Inadequate Control 9 1.3 1.3 no signal
835 Inflammatory Bowel Disease 5 1.3 1.3 no signal
836 Coronary Artery Occlusion 7 1.3 1.3 no signal
837 Diverticulitis 14 1.3 1.3 no signal
838 Anxiety 144 1.3 1.3 no signal
839 Ischaemic Stroke 9 1.3 1.3 no signal
840 Respiratory Tract Congestion 8 1.3 1.3 no signal
841 Product Administration Error 10 1.2 1.2 no signal
842 Rash 217 1.2 1.3 no signal
843 Diplopia 13 1.2 1.2 no signal
844 Intentional Product Use Issue 44 1.2 1.2 no signal
845 Taste Disorder 10 1.2 1.2 no signal
846 Activities Of Daily Living Impaired 10 1.2 1.2 no signal
847 Illness 50 1.2 1.2 no signal
848 Lymphopenia 7 1.2 1.2 no signal
849 Peritonitis Bacterial 5 1.2 1.2 no signal
850 Localised Infection 12 1.2 1.2 no signal
851 Rash Erythematous 23 1.2 1.2 no signal
852 Helicobacter Infection 5 1.2 1.2 no signal
853 Back Disorder 8 1.2 1.2 no signal
854 Conjunctivitis 9 1.2 1.2 no signal
855 Joint Swelling 59 1.2 1.2 no signal
856 Rash Papular 11 1.2 1.2 no signal
857 Needle Issue 14 1.2 1.2 no signal
858 Drug Level Decreased 5 1.2 1.2 no signal
859 Rib Fracture 10 1.2 1.2 no signal
860 Neoplasm Progression 17 1.2 1.2 no signal
861 Leukopenia 24 1.2 1.2 no signal
862 Fear 13 1.2 1.2 no signal
863 Gait Disturbance 92 1.2 1.2 no signal
864 Hot Flush 36 1.2 1.2 no signal
865 Bone Density Decreased 15 1.2 1.2 no signal
866 Cataract 28 1.2 1.2 no signal
867 Seizure 54 1.2 1.2 no signal
868 Serotonin Syndrome 9 1.2 1.2 no signal
869 Lacrimation Increased 14 1.2 1.2 no signal
870 Irritable Bowel Syndrome 10 1.2 1.2 no signal
871 Wound 13 1.2 1.2 no signal
872 Glaucoma 9 1.2 1.2 no signal
873 Fall 155 1.2 1.2 no signal
874 Depression 106 1.2 1.2 no signal
875 Choking 9 1.2 1.2 no signal
876 Back Injury 5 1.1 1.1 no signal
877 Vision Blurred 63 1.1 1.1 no signal
878 Ankylosing Spondylitis 6 1.1 1.1 no signal
879 Loss Of Consciousness 59 1.1 1.1 no signal
880 Treatment Noncompliance 25 1.1 1.1 no signal
881 Blood Count Abnormal 7 1.1 1.1 no signal
882 Dysphagia 43 1.1 1.1 no signal
883 Migraine 43 1.1 1.1 no signal
884 Dysarthria 17 1.1 1.1 no signal
885 Product Use Complaint 7 1.1 1.1 no signal
886 Red Blood Cell Sedimentation Rate Increased 5 1.1 1.1 no signal
887 Therapy Cessation 23 1.1 1.1 no signal
888 Pruritus 170 1.1 1.1 no signal
889 Upper Limb Fracture 9 1.1 1.1 no signal
890 Ocular Hyperaemia 21 1.1 1.1 no signal
891 Nerve Injury 5 1.1 1.1 no signal
892 Basal Cell Carcinoma 7 1.1 1.1 no signal
893 Psoriatic Arthropathy 18 1.1 1.1 no signal
894 Malignant Melanoma 6 1.1 1.1 no signal
895 Toxicity To Various Agents 75 1.1 1.1 no signal
896 Mobility Decreased 32 1.1 1.1 no signal
897 Full Blood Count Decreased 9 1.1 1.1 no signal
898 Vaginal Haemorrhage 19 1.1 1.1 no signal
899 Skin Exfoliation 37 1.1 1.1 no signal
900 Pregnancy 9 1.1 1.1 no signal
901 Rash Pruritic 24 1.1 1.1 no signal
902 Pain Of Skin 12 1.1 1.1 no signal
903 Anger 15 1.1 1.1 no signal
904 Arrhythmia 21 1.1 1.1 no signal
905 Myocarditis 5 1.1 1.1 no signal
906 Scab 5 1.1 1.1 no signal
907 Crying 16 1.1 1.1 no signal
908 Unevaluable Event 33 1.1 1.1 no signal
909 Blood Glucose Decreased 21 1.1 1.1 no signal
910 Influenza Like Illness 36 1.1 1.1 no signal
911 Application Site Rash 6 1.1 1.1 no signal
912 Dizziness 216 1.1 1.1 no signal
913 Erythema 89 1.1 1.1 no signal
914 Dry Eye 21 1.1 1.1 no signal
915 Blood Thyroid Stimulating Hormone Increased 4 1.1 1.1 no signal
916 Prostatic Specific Antigen Increased 6 1.1 1.1 no signal
917 Oral Discomfort 6 1.1 1.1 no signal
918 Gastric Disorder 15 1.1 1.1 no signal
919 Anaphylactic Shock 11 1.1 1.1 no signal
920 Therapy Non-responder 19 1.1 1.1 no signal
921 Skin Fissures 8 1.1 1.1 no signal
922 Fracture 8 1.1 1.1 no signal
923 Therapeutic Response Unexpected 19 1.0 1.0 no signal
924 Pericarditis 7 1.0 1.0 no signal
925 Accident 5 1.0 1.0 no signal
926 Impaired Work Ability 9 1.0 1.0 no signal
927 Dry Skin 55 1.0 1.0 no signal
928 Herpes Zoster 24 1.0 1.0 no signal
929 Therapy Change 4 1.0 1.0 no signal
930 Hyperthyroidism 6 1.0 1.0 no signal
931 Product Dispensing Error 9 1.0 1.0 no signal
932 Fibromyalgia 10 1.0 1.0 no signal
933 Hepatitis C 5 1.0 1.0 no signal
934 Therapeutic Response Shortened 13 1.0 1.0 no signal
935 Hospice Care 4 1.0 1.0 no signal
936 Therapy Interrupted 28 1.0 1.0 no signal
937 Hip Fracture 13 1.0 1.0 no signal
938 Chronic Kidney Disease 31 1.0 1.0 no signal
939 Muscle Spasticity 5 1.0 1.0 no signal
940 Nightmare 14 1.0 1.0 no signal
941 Tooth Extraction 5 1.0 1.0 no signal
942 Dermatitis Allergic 5 1.0 1.0 no signal
943 Syringe Issue 7 1.0 1.0 no signal
944 Contraindicated Product Administered 12 1.0 1.0 no signal
945 Convulsion 23 1.0 1.0 no signal
946 Hypoacusis 17 1.0 1.0 no signal
947 Drug Ineffective 520 1.0 1.0 no signal
948 Ill-defined Disorder 24 1.0 1.0 no signal
949 Eye Pruritus 13 1.0 1.0 no signal
950 Cardiac Disorder 37 1.0 1.0 no signal
951 Malignant Neoplasm Progression 40 1.0 1.0 no signal
952 Thyroid Disorder 6 1.0 1.0 no signal
953 Hypersensitivity 72 1.0 1.0 no signal
954 Rotator Cuff Syndrome 5 1.0 1.0 no signal
955 Injection Site Discomfort 4 1.0 1.0 no signal
956 Folliculitis 4 1.0 1.0 no signal
957 Scratch 4 1.0 1.0 no signal
958 Product Administered At Inappropriate Site 7 1.0 1.0 no signal
959 Hypersomnia 11 1.0 1.0 no signal
960 Swollen Tongue 12 1.0 1.0 no signal
961 Road Traffic Accident 16 1.0 1.0 no signal
962 Injury 27 0.9 0.9 no signal
963 Hereditary Angioedema 4 0.9 0.9 no signal
964 Rash Generalised 10 0.9 0.9 no signal
965 Application Site Erythema 10 0.9 0.9 no signal
966 Injection Site Mass 14 0.9 0.9 no signal
967 Abnormal Behaviour 15 0.9 0.9 no signal
968 Sars-cov-2 Test Positive 5 0.9 0.9 no signal
969 Inappropriate Schedule Of Drug Administration 27 0.9 0.9 no signal
970 Thinking Abnormal 7 0.9 0.9 no signal
971 Urticaria 62 0.9 0.9 no signal
972 Product Taste Abnormal 5 0.9 0.9 no signal
973 Suicidal Ideation 34 0.9 0.9 no signal
974 Mood Altered 10 0.9 0.9 no signal
975 Amnesia 24 0.9 0.9 no signal
976 Eye Disorder 12 0.9 0.9 no signal
977 Renal Disorder 17 0.9 0.9 no signal
978 Psychomotor Hyperactivity 6 0.9 0.9 no signal
979 Blood Glucose Increased 68 0.9 0.9 no signal
980 Abasia 9 0.9 0.9 no signal
981 Glossodynia 8 0.9 0.9 no signal
982 Panic Attack 13 0.9 0.9 no signal
983 Restlessness 13 0.9 0.9 no signal
984 Multiple Sclerosis 17 0.9 0.9 no signal
985 Impaired Driving Ability 4 0.9 0.9 no signal
986 Tardive Dyskinesia 10 0.9 0.9 no signal
987 Visual Impairment 43 0.9 0.9 no signal
988 Therapeutic Response Decreased 21 0.9 0.9 no signal
989 Product Use Issue 65 0.9 0.9 no signal
990 Dyskinesia 14 0.9 0.9 no signal
991 Death 297 0.9 0.9 no signal
992 Pharmaceutical Product Complaint 9 0.8 0.8 no signal
993 Hospitalisation 52 0.8 0.8 no signal
994 Product Prescribing Error 8 0.8 0.8 no signal
995 Tooth Loss 7 0.8 0.8 no signal
996 Colon Cancer 5 0.8 0.8 no signal
997 Neoplasm Malignant 22 0.8 0.8 no signal
998 Hip Arthroplasty 5 0.8 0.8 no signal
999 Injection Site Haemorrhage 26 0.8 0.8 no signal
1000 Brain Neoplasm 3 0.8 0.8 no signal
1001 Medication Error 18 0.8 0.8 no signal
1002 Myelosuppression 11 0.8 0.8 no signal
1003 Product Packaging Issue 3 0.8 0.8 no signal
1004 Tendon Rupture 4 0.8 0.8 no signal
1005 Arthropathy 18 0.8 0.8 no signal
1006 Injection Site Discolouration 4 0.8 0.8 no signal
1007 Poisoning Deliberate 3 0.8 0.8 no signal
1008 Application Site Irritation 4 0.8 0.8 no signal
1009 Drug Administration Error 10 0.8 0.8 no signal
1010 Osteonecrosis Of Jaw 8 0.8 0.8 no signal
1011 Extrapyramidal Disorder 8 0.8 0.8 no signal
1012 Eye Inflammation 3 0.8 0.8 no signal
1013 Hair Colour Changes 4 0.8 0.8 no signal
1014 Application Site Pain 7 0.8 0.8 no signal
1015 Overdose 68 0.8 0.8 no signal
1016 Musculoskeletal Disorder 6 0.8 0.8 no signal
1017 Angina Pectoris 9 0.8 0.8 no signal
1018 Tuberculosis 4 0.8 0.8 no signal
1019 Affect Lability 3 0.8 0.8 no signal
1020 Device Defective 5 0.8 0.8 no signal
1021 Knee Operation 3 0.8 0.8 no signal
1022 Withdrawal Syndrome 13 0.8 0.8 no signal
1023 Swelling Face 20 0.8 0.8 no signal
1024 Cerebrovascular Accident 52 0.8 0.8 no signal
1025 Hand Deformity 4 0.8 0.8 no signal
1026 Inability To Afford Medication 3 0.8 0.8 no signal
1027 Eye Irritation 17 0.8 0.8 no signal
1028 Mania 5 0.8 0.8 no signal
1029 Osteonecrosis 10 0.7 0.7 no signal
1030 Pneumocystis Jirovecii Pneumonia 3 0.7 0.7 no signal
1031 Palmar-plantar Erythrodysaesthesia Syndrome 7 0.7 0.7 no signal
1032 Drug Effect Incomplete 11 0.7 0.7 no signal
1033 Eye Swelling 11 0.7 0.7 no signal
1034 Intentional Self-injury 6 0.7 0.7 no signal
1035 Injection Site Rash 9 0.7 0.7 no signal
1036 Uveitis 4 0.7 0.7 no signal
1037 Epilepsy 9 0.7 0.7 no signal
1038 Hallucination 22 0.7 0.7 no signal
1039 Injection Site Bruising 23 0.7 0.7 no signal
1040 Euphoric Mood 3 0.7 0.7 no signal
1041 Drug Toxicity 4 0.7 0.7 no signal
1042 Procedural Pain 8 0.7 0.7 no signal
1043 Product Odour Abnormal 3 0.7 0.7 no signal
1044 Injection Site Urticaria 7 0.7 0.7 no signal
1045 Dementia 8 0.7 0.7 no signal
1046 Injection Site Pruritus 19 0.7 0.7 no signal
1047 Systemic Lupus Erythematosus 10 0.7 0.7 no signal
1048 Dermatitis Atopic 14 0.7 0.7 no signal
1049 Skin Cancer 6 0.7 0.7 no signal
1050 Glycosylated Haemoglobin Increased 7 0.7 0.7 no signal
1051 Acne 21 0.7 0.7 no signal
1052 Product Quality Issue 37 0.7 0.7 no signal
1053 Accidental Overdose 10 0.7 0.7 no signal
1054 Injection Site Pain 83 0.7 0.7 no signal
1055 Injection Site Nodule 3 0.7 0.7 no signal
1056 Lip Swelling 9 0.7 0.7 no signal
1057 Product Availability Issue 6 0.7 0.7 no signal
1058 Device Failure 4 0.7 0.7 no signal
1059 Injection Site Reaction 18 0.7 0.7 no signal
1060 Aggression 13 0.6 0.6 no signal
1061 Sexual Dysfunction 3 0.6 0.6 no signal
1062 Dystonia 5 0.6 0.6 no signal
1063 Drug Prescribing Error 5 0.6 0.6 no signal
1064 Madarosis 3 0.6 0.6 no signal
1065 Dysgeusia 19 0.6 0.6 no signal
1066 Device Dislocation 11 0.6 0.6 no signal
1067 Mood Swings 8 0.6 0.6 no signal
1068 Incorrect Product Administration Duration 5 0.6 0.6 no signal
1069 Expired Product Administered 8 0.6 0.6 no signal
1070 Product Complaint 6 0.6 0.6 no signal
1071 Injection Site Extravasation 3 0.6 0.6 no signal
1072 Drug Effect Decreased 13 0.6 0.6 no signal
1073 Poisoning 3 0.6 0.6 no signal
1074 Intentional Drug Misuse 5 0.6 0.6 no signal
1075 Treatment Failure 19 0.6 0.6 no signal
1076 Exposure Via Skin Contact 5 0.5 0.5 no signal
1077 Application Site Pruritus 5 0.5 0.5 no signal
1078 Intentional Overdose 14 0.5 0.5 no signal
1079 Adverse Event 20 0.5 0.5 no signal
1080 Rheumatoid Arthritis 24 0.5 0.5 no signal
1081 Incorrect Drug Administration Duration 6 0.5 0.5 no signal
1082 Device Breakage 8 0.5 0.5 no signal
1083 Breast Cancer 19 0.5 0.5 no signal
1084 Abortion Spontaneous 8 0.5 0.5 no signal
1085 Bone Loss 3 0.5 0.5 no signal
1086 Blindness 8 0.5 0.5 no signal
1087 Product Dose Omission 13 0.5 0.5 no signal
1088 Drug Dispensing Error 3 0.5 0.5 no signal
1089 Underdose 14 0.5 0.5 no signal
1090 Incorrect Dose Administered 42 0.5 0.5 no signal
1091 Adverse Drug Reaction 16 0.4 0.4 no signal
1092 Device Malfunction 12 0.4 0.4 no signal
1093 Myocardial Infarction 31 0.4 0.4 no signal
1094 Skin Irritation 8 0.4 0.4 no signal
1095 Multiple Sclerosis Relapse 12 0.4 0.4 no signal
1096 Skin Burning Sensation 12 0.4 0.4 no signal
1097 Device Leakage 7 0.4 0.4 no signal
1098 Hepatic Cancer 4 0.4 0.4 no signal
1099 Emotional Distress 20 0.4 0.4 no signal
1100 Wrong Technique In Drug Usage Process 6 0.4 0.4 no signal
1101 Drug Dose Omission 27 0.4 0.4 no signal
1102 Injection Site Erythema 19 0.4 0.4 no signal
1103 Menstruation Irregular 4 0.4 0.4 no signal
1104 Extra Dose Administered 6 0.4 0.4 no signal
1105 Wrong Technique In Product Usage Process 30 0.4 0.4 no signal
1106 Suicide Attempt 9 0.4 0.4 no signal
1107 Product Storage Error 12 0.3 0.3 no signal
1108 Psoriasis 18 0.3 0.3 no signal
1109 Device Issue 12 0.3 0.3 no signal
1110 No Adverse Event 24 0.3 0.3 no signal
1111 Injection Site Swelling 10 0.3 0.3 no signal
1112 Accidental Exposure To Product 12 0.3 0.3 no signal
1113 Prostate Cancer 9 0.3 0.3 no signal
1114 Incorrect Route Of Drug Administration 4 0.3 0.3 no signal
1115 Drug Withdrawal Syndrome 8 0.2 0.2 no signal
1116 Device Expulsion 4 0.2 0.2 no signal