Reaction

Infective Pulmonary Exacerbation Of Cystic Fibrosis reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,413 reports · 173 co-occurring drugs

As of the last recalculation, Infective Pulmonary Exacerbation Of Cystic Fibrosis appears in 5,413 FAERS reports alongside 173 co-occurring drug terms. The strongest observed disproportionality signal is LUMACAFTOR AND IVACAFTOR (PRR 898.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Lumacaftor And Ivacaftor	1,462	898.3	1,084.2
Dornase Alfa	2,306	787.1	892.6
Tobramycin	1,576	355.1	380.0
Ivacaftor	610	332.7	360.4
Elexacaftor, Tezacaftor, And Ivacaftor	812	294.4	314.9
Tobramycin Solution	607	218.7	230.4
Tobramycin Sulfate	621	217.7	229.2
Pancrelipase	1,317	173.1	179.2
Phytonadione	141	65.6	66.7
Ursosiol	236	48.8	49.4
Sodium Chloride Tablet	779	47.4	47.9
Sodium Chloride Tablets	779	47.4	47.9
Sodium Chloride	796	45.3	45.7
Ursodiol	237	43.7	44.2
Polyethylene Glycol	92	33.2	33.5
Mometasone Furoate And Formoterol Fumarate Dihydrate	98	24.6	24.7
Azithromycin Dihydrate	345	24.1	24.2
Minocycline	69	23.0	23.2
Fluticasone Propionate And Salmeterol Xinafoate	334	22.7	22.8
Dronabinol	39	18.8	18.9
Azithromycin	170	16.7	16.8
Azithromycin Monohydrate	170	16.2	16.2
Amikacin	69	15.7	15.8
Fluticasone Propionate	475	15.3	15.4
Itraconazole	45	14.9	15.0
Albuterol Sulfate	959	14.9	14.9
Vitamin E	115	14.3	14.4
Ciprofloxacin Hydrochloride And Hydrocortisone	71	13.3	13.3
Acetylcysteine	32	13.1	13.2
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	162	12.8	12.8
Oseltamivir	26	12.6	12.6
Polyethylene Glycol 3350	290	12.3	12.3
Albuterol	358	12.2	12.2
Linezolid	91	11.9	12.0
Mometasone Furoate	124	11.7	11.7
Montelukast	240	11.5	11.5
Budesonide And Formoterol Fumarate Dihydrate	261	10.8	10.8
Ciprofloxacin	245	10.7	10.7
Lubiprostone	26	10.6	10.6
Ciprofloxacin Hydrochloride	248	10.2	10.3
Cetiirizine	109	10.1	10.1
Voriconazole Injection	56	10.0	10.0
Ciprofolxacin	179	9.9	9.9
Ciprofloxacin Tablets	179	9.9	9.9
Loratadine Oral	123	9.8	9.9
Montelukast Sodium	295	9.8	9.8
Mometasone	41	8.7	8.7
Insulin Aspart	142	8.5	8.5
Voriconazole	65	8.3	8.3
Sulfamethoxazole And Trimethoprim	176	8.3	8.3
Salmeterol Xinafoate	18	8.1	8.1
Meropenem	63	7.6	7.6
Oseltamivir Phosphate	48	7.6	7.6
Cefepime	28	7.5	7.6
Ergocalciferol	672	7.5	7.5
Guanfacine	15	7.3	7.4
Mupirocin	25	7.2	7.2
Cetirizine Hydrochloride	292	7.1	7.2
Ipratropium Bromide	65	7.1	7.1
Mupirocin Calcium	25	7.0	7.0
Cefepime Hydrochloride	29	7.0	7.0
Levofloxacin	103	6.7	6.7
Levofloxacin In 5% Dextrose	103	6.7	6.7
Ciclesonide	23	6.5	6.5
Loratadine	173	6.4	6.4
Melatonin	88	6.3	6.3
Cetirizine	122	6.2	6.2
Fluticasone Propionate Nasal	48	6.1	6.1
Fexofenadine	26	6.1	6.1
Tranexamic Acid	14	6.1	6.1
Nystatin Ointment	41	6.1	6.1
Nystatin Cream	41	6.0	6.0
Azelastine	28	6.0	6.0
Ferrous Sulfate	77	6.0	6.0
Doxycycline Hyclate	102	5.9	5.9
Doxycycline	102	5.8	5.8
Nystatin	41	5.8	5.8
Lansoprazole	252	5.7	5.7
Budesonide	85	5.6	5.6
Hyoscyamine Sulfate	13	5.5	5.5
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	29	5.4	5.5
Naproxen Sodium, Pseudoephedrine Hydrochloride	29	5.4	5.4
Amoxicillin And Clavulanate Potassium	38	5.4	5.4
Insulin Lispro	186	5.3	5.3
Piperacillin Sodium And Tazobactam Sodium	27	5.3	5.3
Posaconazole Delayed-Release	14	4.9	4.9
Standardized Senna Concentrate	16	4.9	4.9
Omeprazole Magnesium	518	4.8	4.8
Omeprazole	400	4.7	4.7
Umeclidinium	11	4.7	4.7
Instalax Polyethylene Glycol 3350	15	4.7	4.7
Polyethylene Glycol 400	15	4.6	4.6
Dextrose	15	4.4	4.4
Dextrose Monohydrate	15	4.3	4.3
Doxyclycline Hyclate	19	4.3	4.3
Posaconazole	18	4.3	4.3
Cetirizine Hcl	10	4.2	4.2
Alendronate Sodium Tablet	20	4.2	4.2
Antacid	51	4.2	4.2
Clindamycin	30	4.1	4.1
Loratadine Tablet	55	4.0	4.0
Insulin	57	4.0	4.0
Docusate Sodium - Sennosides	33	4.0	4.0
Guaifenesin	31	3.9	3.9
Bisacodyl Suppositories	13	3.9	3.9
Biscodyl	13	3.8	3.8
Bisacodyl	14	3.8	3.8
Hydroxyzine	47	3.8	3.8
Diphenhydramine Hcl	11	3.8	3.8
Calcium Carbonate	65	3.8	3.8
Omalizumab	80	3.6	3.7
Lactulose	36	3.6	3.6
Lidocaine, Menthol	45	3.5	3.5
Benzonatate	15	3.5	3.5
Lidicaine	44	3.5	3.5
Burn Relief	44	3.5	3.5
Lidocaine Hydrochloride And Epinephrine	44	3.5	3.5
Vancomycin Hydrochloride	59	3.5	3.5
Ondansetron	97	3.5	3.5
Ondansetron Tablets	97	3.5	3.5
Febuxostat	15	3.4	3.5
Vitamin C	81	3.4	3.4
Vancomycin	51	3.4	3.4
Clindamycin Phosphate	29	3.4	3.4
Erythromycin	16	3.3	3.3
Zinc	21	3.3	3.3
Ondansetron Hydrochloride	103	3.3	3.3
Lidocaine Hydrochloride And Epinephrine Bitartrate	45	3.3	3.3
Zinc Chloride	21	3.3	3.3
Zinc Gluconate	22	3.2	3.2
Insulin Glargine	200	3.2	3.2
Multivitamin	41	3.2	3.2
Rifampin	12	3.2	3.2
Ibuprofen And Diphenhydramine Citrate	19	3.1	3.1
Mirtazapine	74	3.1	3.1
Lidocaine 4%	44	3.1	3.1
Human Insulin	10	3.1	3.1
Sucralfate	19	3.1	3.1
Doxepin	8	3.0	3.0
Piperacillin And Tazobactam	10	3.0	3.0
Famotidine	89	2.9	2.9
Lidocaine	44	2.9	2.9
Levocetirizine Dihydrochloride	18	2.9	2.9
Tiotropium Bromide Inhalation Spray	8	2.7	2.7
Fluticasone Propionate And Salmeterol	29	2.7	2.7
Hydroxyzine Hydrochloride	9	2.6	2.6
Hydroxyzine Hydrochloride Oral	9	2.6	2.6
Linaclotide	18	2.6	2.6
Sumatriptan Succinate	17	2.6	2.6
Alteplase	10	2.6	2.6
Fluoxetine	44	2.6	2.6
Testosterone	15	2.5	2.5
Insulin Glargine-Yfgn	14	2.5	2.5
Sertraline	74	2.4	2.4
Midazolam	16	2.4	2.4
Bupropion	27	2.3	2.3
Piperacillin Sodium,Tazobactam Sodium	16	2.3	2.3
Benralizumab	12	2.3	2.3
Rocuronium Bromide	7	2.3	2.3
Insulin Glulisine	6	2.3	2.3
Micafungin Sodium	5	2.3	2.3
Sumatriptan	22	2.2	2.2
Ranitidine	112	2.2	2.2
Fexofenadine Hydrochloride	12	2.1	2.1
Tiotropium Bromide	73	2.1	2.1
Amphetamine	4	1.9	1.9
Fluticasone Furoate And Vilanterol Trifenatate	17	1.8	1.8
Insulin Degludec	11	1.8	1.8
Methylphenidate	12	1.6	1.6
Rifaximin	8	1.5	1.5
Sevelamer Carbonate	4	1.3	1.3
Palivizumab	3	0.8	0.8
Adapalene	4	0.1	0.1

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.