OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Pramipexole

1,158 flagged reaction(s) · 74,849 total co-reports · max PRR 1,439.5
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Restless Leg Augmentation Syndrome 70 1,439.5 1,446.1 signal
2 Dopamine Agonist Withdrawal Syndrome 24 1,163.3 1,165.2 signal
3 Parkinsonism Hyperpyrexia Syndrome 45 455.8 457.1 signal
4 Encephalitis Toxic 17 366.2 366.6 signal
5 Gait Spastic 57 270.5 271.5 signal
6 Paraphilia 17 204.2 204.4 signal
7 Dopamine Dysregulation Syndrome 56 196.9 197.6 signal
8 Restless Arm Syndrome 19 192.4 192.7 signal
9 Needle Fatigue 56 191.9 192.6 signal
10 Jealous Delusion 32 174.4 174.8 signal
11 Impulse-control Disorder 195 144.0 145.8 signal
12 Camptocormia 22 139.5 139.7 signal
13 Bronchopulmonary Aspergillosis Allergic 80 131.6 132.3 signal
14 Congenital Hiatus Hernia 18 121.5 121.7 signal
15 Relapsing-remitting Multiple Sclerosis 62 106.5 106.9 signal
16 Malignant Polyp 13 101.4 101.5 signal
17 On And Off Phenomenon 356 99.8 102.2 signal
18 Granuloma Skin 55 97.8 98.2 signal
19 Freezing Phenomenon 234 95.8 97.3 signal
20 Hypersexuality 115 92.0 92.7 signal
21 Pleurothotonus 45 71.4 71.6 signal
22 Stereotypy 46 71.0 71.2 signal
23 Drug-genetic Interaction 16 70.5 70.6 signal
24 Stoma Site Reaction 33 70.4 70.6 signal
25 Stoma Site Erythema 88 67.9 68.3 signal
26 Penis Injury 17 67.5 67.5 signal
27 Cerebral Hypoperfusion 21 66.0 66.1 signal
28 Binge Eating 47 63.0 63.2 signal
29 Total Lung Capacity Decreased 70 62.9 63.2 signal
30 Parkinsonian Gait 27 62.4 62.5 signal
31 Gambling 49 59.6 59.8 signal
32 Compulsive Shopping 86 59.6 60.0 signal
33 Euthanasia 13 58.8 58.9 signal
34 Gambling Disorder 109 57.5 57.9 signal
35 Anticoagulant Therapy 11 56.8 56.8 signal
36 Reduced Facial Expression 39 55.7 55.9 signal
37 Dropped Head Syndrome 15 55.2 55.2 signal
38 Blood Parathyroid Hormone Decreased 57 54.7 54.9 signal
39 Sleep Attacks 18 54.3 54.4 signal
40 Pneumococcal Infection 22 53.6 53.7 signal
41 Drug Therapy 12 53.6 53.6 signal
42 Analgesic Therapy 11 51.1 51.2 signal
43 Stoma Site Hypergranulation 22 49.6 49.7 signal
44 Stoma Site Discharge 94 48.8 49.1 signal
45 Fibroma 31 47.5 47.6 signal
46 Periodic Limb Movement Disorder 12 46.3 46.3 signal
47 Monoparesis 58 45.3 45.4 signal
48 Hallucination, Tactile 21 45.2 45.3 signal
49 Stoma Site Irritation 17 44.1 44.2 signal
50 Stoma Site Pain 42 40.7 40.8 signal
51 Hyperkinesia 60 40.6 40.8 signal
52 Suspiciousness 20 40.6 40.7 signal
53 Multiple Drug Therapy 20 40.6 40.6 signal
54 Pathological Gambling 47 39.5 39.6 signal
55 Compulsions 18 39.0 39.0 signal
56 Deep Brain Stimulation 16 38.9 39.0 signal
57 Lung Opacity 70 38.4 38.6 signal
58 Orthostatic Intolerance 19 37.6 37.7 signal
59 Bradykinesia 154 37.3 37.7 signal
60 Stoma Site Infection 34 37.2 37.2 signal
61 Restless Legs Syndrome 457 35.4 36.5 signal
62 Resting Tremor 16 34.7 34.8 signal
63 Stoma Site Inflammation 18 34.1 34.2 signal
64 Panniculitis 57 33.3 33.4 signal
65 Hypertonic Bladder 64 31.3 31.4 signal
66 Rheumatoid Nodule 57 28.7 28.8 signal
67 Akinesia 40 27.1 27.2 signal
68 Libido Increased 39 26.9 27.0 signal
69 Skin Neoplasm Excision 15 26.9 27.0 signal
70 Pleuritic Pain 50 25.3 25.3 signal
71 Therapeutic Product Effect Variable 65 23.8 23.9 signal
72 Dyskinesia 690 23.8 24.9 signal
73 Muscle Rigidity 202 23.6 24.0 signal
74 Acute Psychosis 40 22.6 22.7 signal
75 Device Loosening 13 21.4 21.5 signal
76 Breath Sounds Abnormal 74 20.9 21.0 signal
77 Drug Tolerance Decreased 42 20.9 21.0 signal
78 Impulsive Behaviour 56 20.8 20.9 signal
79 Hallucination, Visual 306 20.4 20.8 signal
80 Stoma Site Haemorrhage 22 20.2 20.2 signal
81 Torticollis 29 19.3 19.3 signal
82 Uterine Prolapse 15 19.2 19.3 signal
83 Drug Effect Variable 15 18.2 18.2 signal
84 Sudden Onset Of Sleep 18 18.0 18.0 signal
85 Neoplasm Skin 20 17.9 17.9 signal
86 Device Alarm Issue 23 17.8 17.8 signal
87 Stoma Complication 13 17.8 17.8 signal
88 Drug Dispensed To Wrong Patient 12 17.7 17.7 signal
89 Chronic Fatigue Syndrome 17 17.0 17.1 signal
90 Infusion Site Nodule 11 17.0 17.0 signal
91 Device Connection Issue 25 17.0 17.0 signal
92 Chorea 21 16.9 16.9 signal
93 Rheumatoid Factor Positive 70 16.9 17.0 signal
94 Rales 70 16.8 16.9 signal
95 Bronchiectasis 78 16.3 16.4 signal
96 Nocturia 141 16.2 16.3 signal
97 Skin Necrosis 59 15.8 15.8 signal
98 Blood Pressure Diastolic Abnormal 29 15.7 15.7 signal
99 Hallucination 807 15.0 15.8 signal
100 Posture Abnormal 35 15.0 15.0 signal
101 Obstructive Sleep Apnoea Syndrome 15 14.9 15.0 signal
102 Cataplexy 15 14.6 14.6 signal
103 Hallucinations, Mixed 43 14.2 14.2 signal
104 Sputum Discoloured 93 13.7 13.7 signal
105 Peripheral Sensorimotor Neuropathy 12 13.4 13.5 signal
106 Delusion 149 13.4 13.5 signal
107 Product Residue Present 51 13.4 13.4 signal
108 Aspiration 104 13.3 13.4 signal
109 Pre-existing Condition Improved 60 13.2 13.3 signal
110 Tinea Pedis 15 13.0 13.0 signal
111 Spinal Stenosis 38 12.9 12.9 signal
112 Blood Calcium Increased 81 12.8 12.9 signal
113 Sinus Pain 21 12.6 12.6 signal
114 Fine Motor Skill Dysfunction 26 12.5 12.5 signal
115 Dystonia 175 12.5 12.6 signal
116 Obsessive-compulsive Disorder 72 12.4 12.4 signal
117 Micturition Urgency 98 12.0 12.1 signal
118 Adjustment Disorder 11 11.7 11.7 signal
119 Pulmonary Fibrosis 161 11.7 11.8 signal
120 Abnormal Sleep-related Event 11 11.5 11.5 signal
121 Bipolar I Disorder 18 11.4 11.4 signal
122 Tension 49 11.1 11.2 signal
123 Parkinsonism 78 11.1 11.1 signal
124 Food Interaction 14 11.0 11.0 signal
125 Muscle Spasticity 97 10.8 10.9 signal
126 Obsessive Thoughts 14 10.7 10.7 signal
127 Sleep Talking 13 10.5 10.6 signal
128 Anticholinergic Syndrome 12 10.4 10.4 signal
129 Clostridium Test Positive 16 10.2 10.2 signal
130 Neuroleptic Malignant Syndrome 87 10.1 10.2 signal
131 Red Blood Cell Sedimentation Rate Increased 81 10.1 10.2 signal
132 Vaginal Infection 34 10.0 10.0 signal
133 Sedation Complication 18 10.0 10.0 signal
134 Illusion 12 9.9 10.0 signal
135 Troponin Increased 54 9.9 9.9 signal
136 Depressive Symptom 25 9.9 9.9 signal
137 Hyperparathyroidism Secondary 18 9.8 9.9 signal
138 Bradypnoea 19 9.8 9.8 signal
139 Hypomania 26 9.8 9.8 signal
140 Sleep Apnoea Syndrome 133 9.6 9.7 signal
141 Skin Abrasion 32 9.5 9.5 signal
142 Hyperphagia 27 9.4 9.4 signal
143 Yawning 18 9.3 9.3 signal
144 Orthostatic Hypotension 117 9.3 9.3 signal
145 Ataxia 79 9.2 9.2 signal
146 Blood Test Abnormal 92 9.1 9.1 signal
147 Nonspecific Reaction 35 9.0 9.0 signal
148 Somnambulism 42 8.8 8.8 signal
149 Obstructive Airways Disorder 71 8.8 8.8 signal
150 Infusion Site Bruising 13 8.5 8.5 signal
151 Wheelchair User 27 8.4 8.4 signal
152 Attention Deficit Hyperactivity Disorder 25 8.3 8.3 signal
153 Inappropriate Antidiuretic Hormone Secretion 61 8.3 8.3 signal
154 Drug Tolerance 30 8.2 8.2 signal
155 Sleep Deficit 12 8.0 8.0 signal
156 Listless 19 8.0 8.0 signal
157 Rehabilitation Therapy 22 7.9 7.9 signal
158 Persecutory Delusion 14 7.9 7.9 signal
159 Behaviour Disorder 30 7.8 7.8 signal
160 Product Administration Interrupted 43 7.8 7.8 signal
161 Hypercalcaemia 69 7.7 7.8 signal
162 Coma Scale Abnormal 16 7.7 7.7 signal
163 Therapeutic Product Effect Delayed 25 7.7 7.7 signal
164 Cardiac Dysfunction 20 7.6 7.6 signal
165 Logorrhoea 19 7.4 7.5 signal
166 Pulmonary Mass 80 7.4 7.5 signal
167 Hypercapnia 16 7.4 7.4 signal
168 Nephrogenic Anaemia 25 7.4 7.4 signal
169 Motor Dysfunction 54 7.4 7.4 signal
170 Dyschezia 16 7.3 7.3 signal
171 Wound Complication 18 7.2 7.2 signal
172 Device Kink 17 7.1 7.1 signal
173 Skin Laceration 55 7.0 7.1 signal
174 Therapeutic Response Shortened 161 7.0 7.1 signal
175 Central Nervous System Lesion 69 6.9 6.9 signal
176 Poor Quality Sleep 106 6.8 6.9 signal
177 Blood Pressure Inadequately Controlled 30 6.8 6.8 signal
178 Ulcer 77 6.7 6.7 signal
179 Hyperventilation 28 6.7 6.7 signal
180 Immobile 21 6.7 6.7 signal
181 Blood Pressure Systolic Abnormal 12 6.7 6.7 signal
182 Hypokinesia 70 6.7 6.7 signal
183 Infusion Site Reaction 14 6.7 6.7 signal
184 Prescribed Underdose 95 6.6 6.6 signal
185 Psychotic Disorder 140 6.5 6.6 signal
186 Basal Cell Carcinoma 74 6.5 6.6 signal
187 Movement Disorder 152 6.5 6.6 signal
188 Cervical Vertebral Fracture 16 6.4 6.4 signal
189 Psychomotor Skills Impaired 12 6.3 6.3 signal
190 Autonomic Nervous System Imbalance 13 6.2 6.2 signal
191 Blood Pressure Diastolic Decreased 33 6.1 6.2 signal
192 Balance Disorder 384 6.1 6.3 signal
193 Exercise Tolerance Decreased 25 6.0 6.1 signal
194 Delirium 151 6.0 6.1 signal
195 Tenosynovitis 12 6.0 6.0 signal
196 Transaminases Increased 96 6.0 6.0 signal
197 Loss Of Personal Independence In Daily Activities 205 6.0 6.0 signal
198 Middle Insomnia 80 5.9 6.0 signal
199 Hydronephrosis 32 5.9 5.9 signal
200 Synovitis 77 5.9 5.9 signal
201 Colitis Microscopic 20 5.9 5.9 signal
202 Walking Aid User 28 5.8 5.8 signal
203 Initial Insomnia 43 5.8 5.8 signal
204 Device Occlusion 58 5.8 5.8 signal
205 Abnormal Dreams 115 5.7 5.7 signal
206 Tooth Abscess 42 5.7 5.7 signal
207 Cognitive Disorder 190 5.6 5.7 signal
208 Alcohol Abuse 11 5.6 5.6 signal
209 Paranoia 70 5.6 5.6 signal
210 Cholecystitis Infective 11 5.5 5.5 signal
211 Liver Function Test Increased 84 5.4 5.5 signal
212 Activated Partial Thromboplastin Time Prolonged 20 5.4 5.4 signal
213 Feeling Of Body Temperature Change 23 5.4 5.4 signal
214 Salivary Hypersecretion 39 5.4 5.4 signal
215 Faeces Hard 15 5.3 5.3 signal
216 Dysarthria 145 5.3 5.4 signal
217 Food Intolerance 14 5.3 5.3 signal
218 Sopor 51 5.3 5.3 signal
219 Dysgraphia 25 5.2 5.2 signal
220 Mania 62 5.2 5.2 signal
221 C-reactive Protein Abnormal 24 5.2 5.2 signal
222 Therapeutic Product Effect Decreased 166 5.2 5.2 signal
223 Intervertebral Disc Disorder 16 5.1 5.1 signal
224 Musculoskeletal Stiffness 324 5.1 5.2 signal
225 Tremor 612 5.1 5.3 signal
226 Medication Error 204 5.1 5.1 signal
227 Abnormal Faeces 30 5.1 5.1 signal
228 Self-medication 15 5.0 5.0 signal
229 Clavicle Fracture 14 5.0 5.0 signal
230 Fluid Intake Reduced 18 5.0 5.0 signal
231 Mobility Decreased 261 5.0 5.1 signal
232 Drooling 25 5.0 5.0 signal
233 Muscle Rupture 14 5.0 5.0 signal
234 Nerve Compression 33 4.9 5.0 signal
235 Restlessness 129 4.9 4.9 signal
236 Peroneal Nerve Palsy 20 4.9 4.9 signal
237 Gait Disturbance 669 4.8 5.0 signal
238 Enuresis 14 4.8 4.8 signal
239 Arthritis Infective 16 4.8 4.8 signal
240 Speech Disorder 180 4.7 4.8 signal
241 Rotator Cuff Syndrome 44 4.7 4.7 signal
242 Fall 1,130 4.7 5.0 signal
243 Hallucination, Auditory 54 4.7 4.7 signal
244 Therapeutic Product Effect Incomplete 237 4.6 4.7 signal
245 Dementia 93 4.6 4.6 signal
246 Spinal Operation 40 4.6 4.6 signal
247 Finger Deformity 16 4.6 4.6 signal
248 Drug Eruption 58 4.5 4.6 signal
249 Blood Pressure Fluctuation 79 4.5 4.5 signal
250 Embedded Device 32 4.5 4.5 signal
251 Dysstasia 95 4.5 4.5 signal
252 Alcoholism 14 4.5 4.5 signal
253 Abnormal Behaviour 128 4.4 4.5 signal
254 Psychomotor Hyperactivity 53 4.4 4.4 signal
255 Erysipelas 16 4.4 4.4 signal
256 Hypoxia 111 4.4 4.4 signal
257 End Stage Renal Disease 58 4.3 4.4 signal
258 Haemoptysis 88 4.3 4.4 signal
259 Hyperpyrexia 13 4.3 4.3 signal
260 Psychiatric Symptom 23 4.3 4.3 signal
261 Gait Inability 103 4.3 4.3 signal
262 Benign Prostatic Hyperplasia 16 4.3 4.3 signal
263 Blood Pressure Systolic Increased 60 4.2 4.2 signal
264 Carpal Tunnel Syndrome 43 4.2 4.2 signal
265 Hypothermia 31 4.2 4.2 signal
266 Neuralgia 74 4.2 4.2 signal
267 Erectile Dysfunction 78 4.2 4.2 signal
268 Intentional Underdose 22 4.2 4.2 signal
269 Bowel Movement Irregularity 23 4.2 4.2 signal
270 Infusion Site Erythema 25 4.2 4.2 signal
271 Memory Impairment 413 4.1 4.2 signal
272 Cerebral Atrophy 12 4.1 4.1 signal
273 Personality Change 28 4.1 4.1 signal
274 Skin Ulcer 77 4.1 4.1 signal
275 Hiccups 24 4.1 4.1 signal
276 General Physical Health Deterioration 338 4.1 4.1 signal
277 Faecaloma 16 4.1 4.1 signal
278 Urinary Incontinence 87 4.1 4.1 signal
279 Hyperthermia 22 4.0 4.0 signal
280 Peripheral Sensory Neuropathy 17 4.0 4.0 signal
281 Joint Injury 62 4.0 4.0 signal
282 Foot Deformity 32 4.0 4.0 signal
283 Pollakiuria 120 4.0 4.0 signal
284 Bradycardia 152 3.9 4.0 signal
285 Frustration Tolerance Decreased 23 3.9 3.9 signal
286 Pneumonia Aspiration 71 3.9 3.9 signal
287 Foot Operation 14 3.9 3.9 signal
288 Terminal State 19 3.9 3.9 signal
289 Post-traumatic Stress Disorder 19 3.9 3.9 signal
290 Decubitus Ulcer 23 3.9 3.9 signal
291 Apathy 41 3.9 3.9 signal
292 Hip Surgery 15 3.9 3.9 signal
293 Confusional State 455 3.9 4.0 signal
294 Limb Discomfort 86 3.8 3.8 signal
295 Tearfulness 12 3.8 3.8 signal
296 Somnolence 557 3.8 3.9 signal
297 Peripheral Swelling 423 3.8 3.9 signal
298 Lymphoedema 19 3.8 3.8 signal
299 Dysphoria 14 3.8 3.8 signal
300 C-reactive Protein Increased 100 3.8 3.8 signal
301 Grip Strength Decreased 24 3.8 3.8 signal
302 Bipolar Disorder 30 3.8 3.8 signal
303 Oedema Peripheral 335 3.8 3.8 signal
304 Incontinence 29 3.8 3.8 signal
305 Diplopia 71 3.8 3.8 signal
306 Major Depression 20 3.8 3.8 signal
307 Condition Aggravated 824 3.8 3.9 signal
308 Thinking Abnormal 51 3.8 3.8 signal
309 Diabetes Mellitus Inadequate Control 48 3.7 3.7 signal
310 Skin Mass 18 3.7 3.7 signal
311 Pelvic Fracture 21 3.7 3.7 signal
312 Polyneuropathy 32 3.7 3.7 signal
313 Agitation 198 3.7 3.7 signal
314 Device Dislocation 116 3.7 3.7 signal
315 Wrist Fracture 32 3.7 3.7 signal
316 Upper Respiratory Tract Infection 123 3.7 3.7 signal
317 Infusion Related Reaction 175 3.7 3.7 signal
318 Lower Respiratory Tract Infection 120 3.7 3.7 signal
319 Localised Infection 64 3.6 3.7 signal
320 Chronic Kidney Disease 202 3.6 3.7 signal
321 Brain Fog 38 3.6 3.6 signal
322 Sleep Disorder 181 3.6 3.6 signal
323 Foot Fracture 49 3.6 3.6 signal
324 Scoliosis 16 3.6 3.6 signal
325 Suicidal Ideation 235 3.5 3.6 signal
326 Myositis 23 3.5 3.5 signal
327 Mental Impairment 62 3.5 3.5 signal
328 Head Injury 80 3.5 3.5 signal
329 Aggression 126 3.5 3.5 signal
330 Blood Creatinine Increased 164 3.5 3.5 signal
331 Acute Pulmonary Oedema 14 3.4 3.4 signal
332 Depressed Mood 131 3.4 3.5 signal
333 Iron Deficiency 11 3.4 3.4 signal
334 Hiatus Hernia 32 3.4 3.4 signal
335 Back Disorder 40 3.4 3.4 signal
336 Disorientation 97 3.4 3.4 signal
337 Meniscus Injury 15 3.4 3.4 signal
338 Impaired Quality Of Life 35 3.4 3.4 signal
339 Myoclonus 29 3.4 3.4 signal
340 Arthritis 191 3.3 3.4 signal
341 Adrenal Insufficiency 29 3.3 3.3 signal
342 Suicide Attempt 147 3.3 3.4 signal
343 Skin Infection 27 3.3 3.3 signal
344 Sedation 63 3.3 3.3 signal
345 Osteoarthritis 102 3.3 3.3 signal
346 Hip Fracture 77 3.3 3.3 signal
347 Muscle Atrophy 30 3.3 3.3 signal
348 Blood Cholesterol Abnormal 11 3.3 3.3 signal
349 Blood Iron Decreased 28 3.3 3.3 signal
350 Device Use Issue 41 3.3 3.3 signal
351 Hyponatraemia 133 3.3 3.3 signal
352 Chronic Obstructive Pulmonary Disease 122 3.2 3.2 signal
353 Ligament Sprain 23 3.2 3.2 signal
354 Trismus 12 3.2 3.2 signal
355 Polyuria 19 3.2 3.2 signal
356 Hypercholesterolaemia 22 3.2 3.2 signal
357 Hypervolaemia 11 3.2 3.2 signal
358 Arthropathy 127 3.1 3.2 signal
359 Infusion Site Swelling 14 3.1 3.1 signal
360 Heart Rate Decreased 80 3.1 3.1 signal
361 Drug Interaction 359 3.1 3.2 signal
362 Hypophagia 57 3.1 3.1 signal
363 Overweight 12 3.1 3.1 signal
364 Social Avoidant Behaviour 13 3.1 3.1 signal
365 Renal Tubular Necrosis 22 3.1 3.1 signal
366 Choking 43 3.1 3.1 signal
367 Hyperthyroidism 32 3.0 3.1 signal
368 Pulmonary Thrombosis 24 3.0 3.0 signal
369 Impaired Gastric Emptying 28 3.0 3.0 signal
370 Musculoskeletal Disorder 42 3.0 3.0 signal
371 Acute Respiratory Failure 42 3.0 3.0 signal
372 Rib Fracture 45 3.0 3.0 signal
373 Brain Injury 22 3.0 3.0 signal
374 Constipation 474 3.0 3.1 signal
375 Insomnia 584 3.0 3.1 signal
376 Screaming 14 3.0 3.0 signal
377 Sars-cov-2 Test Positive 29 3.0 3.0 signal
378 Knee Operation 21 3.0 3.0 signal
379 Withdrawal Syndrome 91 3.0 3.0 signal
380 Unevaluable Event 163 3.0 3.0 signal
381 Intervertebral Disc Degeneration 20 3.0 3.0 signal
382 Feeling Drunk 16 3.0 3.0 signal
383 Limb Injury 58 3.0 3.0 signal
384 Device Physical Property Issue 16 2.9 2.9 signal
385 Renal Cyst 17 2.9 2.9 signal
386 Device Issue 186 2.9 3.0 signal
387 Labelled Drug-drug Interaction Medication Error 19 2.9 2.9 signal
388 Nightmare 74 2.9 2.9 signal
389 Urinary Tract Infection 362 2.9 3.0 signal
390 Disturbance In Attention 115 2.9 2.9 signal
391 Blood Pressure Abnormal 42 2.9 2.9 signal
392 Wound Infection 23 2.9 2.9 signal
393 Thermal Burn 15 2.9 2.9 signal
394 Therapeutic Response Unexpected 95 2.9 2.9 signal
395 Inflammation 108 2.9 2.9 signal
396 Coronavirus Infection 14 2.9 2.9 signal
397 Post Procedural Infection 17 2.9 2.9 signal
398 Joint Dislocation 22 2.9 2.9 signal
399 Wound 58 2.9 2.9 signal
400 Blood Magnesium Decreased 18 2.9 2.9 signal
401 Dizziness Postural 20 2.9 2.9 signal
402 Stress Cardiomyopathy 12 2.9 2.9 signal
403 Faeces Soft 15 2.9 2.9 signal
404 Abnormal Loss Of Weight 14 2.9 2.9 signal
405 Bruxism 11 2.8 2.8 signal
406 Myasthenia Gravis 16 2.8 2.8 signal
407 Wheezing 120 2.8 2.8 signal
408 Post Procedural Complication 39 2.8 2.8 signal
409 Anal Incontinence 18 2.8 2.8 signal
410 Therapy Non-responder 90 2.8 2.8 signal
411 Eating Disorder 43 2.8 2.8 signal
412 Contraindicated Product Administered 60 2.7 2.7 signal
413 Sensory Loss 16 2.7 2.7 signal
414 Hypersomnia 56 2.7 2.7 signal
415 Sciatica 31 2.7 2.7 signal
416 Product Prescribing Error 46 2.7 2.7 signal
417 Clostridium Difficile Infection 42 2.7 2.7 signal
418 Hypophosphataemia 14 2.6 2.6 signal
419 Altered State Of Consciousness 41 2.6 2.6 signal
420 Full Blood Count Abnormal 20 2.6 2.6 signal
421 Blood Potassium Decreased 57 2.6 2.6 signal
422 Gout 34 2.6 2.6 signal
423 Transient Ischaemic Attack 64 2.6 2.6 signal
424 Gastrooesophageal Reflux Disease 151 2.6 2.6 signal
425 Aphasia 57 2.6 2.6 signal
426 Cystitis 60 2.6 2.6 signal
427 Joint Swelling 226 2.6 2.6 signal
428 Intervertebral Disc Protrusion 41 2.6 2.6 signal
429 Dysphagia 177 2.6 2.6 signal
430 Cellulitis 94 2.6 2.6 signal
431 Feeding Disorder 37 2.6 2.6 signal
432 Pleural Effusion 113 2.6 2.6 signal
433 Fibromyalgia 45 2.6 2.6 signal
434 Vitamin D Deficiency 18 2.5 2.5 signal
435 Drug Effect Less Than Expected 26 2.5 2.5 signal
436 Hand Fracture 13 2.5 2.5 signal
437 Hospice Care 18 2.5 2.5 signal
438 Hepatic Steatosis 34 2.5 2.5 signal
439 Hypertension 385 2.5 2.5 signal
440 Muscular Weakness 205 2.5 2.5 signal
441 Panic Reaction 13 2.5 2.5 signal
442 Anxiety 513 2.5 2.5 signal
443 Oxygen Saturation Decreased 100 2.5 2.5 signal
444 Depression 409 2.5 2.5 signal
445 Coordination Abnormal 25 2.5 2.5 signal
446 Decreased Activity 19 2.4 2.4 signal
447 Ulcer Haemorrhage 12 2.4 2.4 signal
448 Pseudomonas Infection 15 2.4 2.4 signal
449 Disability 35 2.4 2.4 signal
450 Haematoma 46 2.4 2.4 signal
451 Scab 20 2.4 2.4 signal
452 Tubulointerstitial Nephritis 33 2.4 2.4 signal
453 Prescribed Overdose 34 2.4 2.4 signal
454 Lymphocyte Count Decreased 31 2.4 2.4 signal
455 Mental Disorder 76 2.4 2.4 signal
456 Musculoskeletal Chest Pain 27 2.4 2.4 signal
457 Urinary Retention 58 2.4 2.4 signal
458 Bursitis 21 2.4 2.4 signal
459 Asthma 195 2.4 2.4 signal
460 Hysterectomy 15 2.4 2.4 signal
461 Urosepsis 16 2.4 2.4 signal
462 Crying 63 2.4 2.4 signal
463 Serotonin Syndrome 33 2.4 2.4 signal
464 Amnesia 112 2.4 2.4 signal
465 Fluid Retention 87 2.4 2.4 signal
466 Stress 123 2.4 2.4 signal
467 Bladder Disorder 17 2.4 2.4 signal
468 Seasonal Allergy 24 2.3 2.3 signal
469 Upper Limb Fracture 34 2.3 2.3 signal
470 Right Ventricular Failure 12 2.3 2.3 signal
471 Skin Lesion 46 2.3 2.3 signal
472 Blood Pressure Decreased 112 2.3 2.3 signal
473 Intentional Self-injury 34 2.3 2.3 signal
474 Intentional Dose Omission 46 2.3 2.3 signal
475 Cardiogenic Shock 24 2.3 2.3 signal
476 Emphysema 17 2.3 2.3 signal
477 Myocarditis 19 2.3 2.3 signal
478 Dry Throat 17 2.3 2.3 signal
479 Pulmonary Hypertension 35 2.3 2.3 signal
480 Dry Mouth 135 2.3 2.3 signal
481 Drug Intolerance 160 2.3 2.3 signal
482 Acute Kidney Injury 253 2.3 2.3 signal
483 Hypotension 331 2.3 2.3 signal
484 Multiple Sclerosis Relapse 114 2.3 2.3 signal
485 Feeling Cold 46 2.3 2.3 signal
486 Hip Arthroplasty 25 2.3 2.3 signal
487 Muscle Twitching 38 2.3 2.3 signal
488 Petechiae 17 2.3 2.3 signal
489 Hepatic Enzyme Increased 111 2.3 2.3 signal
490 Miosis 13 2.2 2.2 signal
491 Dyspnoea Exertional 61 2.2 2.2 signal
492 Tachypnoea 22 2.2 2.2 signal
493 Atrial Flutter 13 2.2 2.2 signal
494 Cardiomyopathy 24 2.2 2.2 signal
495 Cough 452 2.2 2.3 signal
496 Myopathy 14 2.2 2.2 signal
497 Multiple Organ Dysfunction Syndrome 45 2.2 2.2 signal
498 Contusion 155 2.2 2.2 signal
499 Nodule 21 2.2 2.2 signal
500 Blood Creatine Phosphokinase Increased 47 2.2 2.2 signal
501 Clostridium Difficile Colitis 17 2.2 2.2 signal
502 Rheumatoid Arthritis 181 2.2 2.2 signal
503 Pneumonia 517 2.2 2.2 signal
504 Bedridden 21 2.2 2.2 signal
505 Peripheral Coldness 22 2.2 2.2 signal
506 Spinal Osteoarthritis 14 2.2 2.2 signal
507 Impaired Healing 52 2.2 2.2 signal
508 Spinal Disorder 15 2.2 2.2 signal
509 Emotional Disorder 49 2.2 2.2 signal
510 Formication 11 2.2 2.2 signal
511 Sluggishness 16 2.2 2.2 signal
512 Hypoaesthesia 236 2.2 2.2 signal
513 Underdose 115 2.2 2.2 signal
514 Back Injury 17 2.2 2.2 signal
515 Aortic Aneurysm 12 2.2 2.2 signal
516 Infusion Site Pain 20 2.2 2.2 signal
517 Product Dose Omission In Error 42 2.2 2.2 signal
518 Muscle Spasms 287 2.2 2.2 signal
519 Skin Reaction 22 2.2 2.2 signal
520 Aspartate Aminotransferase Increased 83 2.2 2.2 signal
521 Ageusia 39 2.1 2.2 signal
522 Rash Pruritic 84 2.1 2.2 signal
523 Dizziness 771 2.1 2.2 signal
524 Injection Site Nodule 17 2.1 2.1 signal
525 Incorrect Route Of Product Administration 26 2.1 2.1 signal
526 Depressed Level Of Consciousness 61 2.1 2.1 signal
527 Dermatitis 32 2.1 2.1 signal
528 Tendon Rupture 19 2.1 2.1 signal
529 Cardiomegaly 19 2.1 2.1 signal
530 Affective Disorder 12 2.1 2.1 signal
531 Dysphonia 89 2.1 2.1 signal
532 Anaemia 290 2.1 2.1 signal
533 Abasia 38 2.1 2.1 signal
534 Inadequate Analgesia 13 2.1 2.1 signal
535 Renal Pain 16 2.1 2.1 signal
536 Asthenia 569 2.1 2.1 signal
537 Muscle Strain 13 2.1 2.1 signal
538 Road Traffic Accident 63 2.1 2.1 signal
539 Spinal Fracture 30 2.1 2.1 signal
540 Obesity 24 2.1 2.1 signal
541 Mass 21 2.1 2.1 signal
542 Impaired Driving Ability 17 2.1 2.1 signal
543 Treatment Noncompliance 81 2.1 2.1 signal
544 Quality Of Life Decreased 20 2.1 2.1 signal
545 Therapy Cessation 76 2.0 2.1 signal
546 Knee Arthroplasty 31 2.0 2.0 signal
547 Skin Cancer 32 2.0 2.0 signal
548 Hepatitis 38 2.0 2.0 signal
549 Panic Attack 54 2.0 2.0 signal
550 Abdominal Pain 344 2.0 2.1 signal
551 Head Discomfort 26 2.0 2.0 signal
552 Pharyngeal Oedema 23 2.0 2.0 signal
553 Pain In Extremity 435 2.0 2.1 signal
554 Bronchitis 109 2.0 2.0 signal
555 Upper-airway Cough Syndrome 12 2.0 2.0 signal
556 Weight Decreased 408 2.0 2.0 signal
557 Therapeutic Response Decreased 88 2.0 2.0 signal
558 Retching 31 2.0 2.0 signal
559 Gastrointestinal Infection 13 2.0 2.0 signal
560 Madarosis 17 2.0 2.0 no signal
561 Tooth Fracture 16 2.0 2.0 no signal
562 Hyperhidrosis 187 2.0 2.0 no signal
563 Cyst 18 2.0 2.0 no signal
564 Feeling Abnormal 348 2.0 2.0 no signal
565 Eosinophil Count Increased 12 2.0 2.0 no signal
566 Intentional Product Use Issue 127 2.0 2.0 no signal
567 Cytomegalovirus Infection 24 2.0 2.0 no signal
568 Renal Failure 193 2.0 2.0 no signal
569 Productive Cough 68 2.0 2.0 no signal
570 Anhedonia 38 2.0 2.0 no signal
571 Cholecystitis 17 2.0 2.0 no signal
572 Fatigue 1,108 2.0 2.0 no signal
573 Back Pain 330 2.0 2.0 no signal
574 Atrioventricular Block 11 2.0 2.0 no signal
575 Iron Deficiency Anaemia 13 1.9 1.9 no signal
576 Brain Neoplasm 13 1.9 1.9 no signal
577 Deafness 37 1.9 1.9 no signal
578 Throat Irritation 63 1.9 1.9 no signal
579 Hernia 27 1.9 1.9 no signal
580 Hypoglycaemia 68 1.9 1.9 no signal
581 Vitamin D Decreased 12 1.9 1.9 no signal
582 Unresponsive To Stimuli 36 1.9 1.9 no signal
583 Neck Pain 78 1.9 1.9 no signal
584 Akathisia 19 1.9 1.9 no signal
585 Electrolyte Imbalance 16 1.9 1.9 no signal
586 Pericardial Effusion 32 1.9 1.9 no signal
587 Ocular Discomfort 15 1.9 1.9 no signal
588 Generalised Oedema 17 1.9 1.9 no signal
589 Hypoacusis 59 1.9 1.9 no signal
590 Presyncope 33 1.9 1.9 no signal
591 Irritability 82 1.9 1.9 no signal
592 Feeling Jittery 26 1.9 1.9 no signal
593 Euphoric Mood 14 1.9 1.9 no signal
594 Pain 831 1.9 1.9 no signal
595 Respiratory Rate Increased 12 1.9 1.9 no signal
596 Surgery 78 1.9 1.9 no signal
597 Affect Lability 13 1.9 1.9 no signal
598 Malignant Melanoma 18 1.8 1.8 no signal
599 Adverse Drug Reaction 120 1.8 1.9 no signal
600 Alanine Aminotransferase Increased 82 1.8 1.8 no signal
601 Nephrolithiasis 61 1.8 1.8 no signal
602 Blood Sodium Decreased 25 1.8 1.8 no signal
603 Drug Hypersensitivity 258 1.8 1.8 no signal
604 Lung Disorder 65 1.8 1.8 no signal
605 Sepsis 148 1.8 1.8 no signal
606 Product Dose Omission Issue 377 1.8 1.8 no signal
607 Loss Of Consciousness 169 1.8 1.8 no signal
608 Visual Impairment 160 1.8 1.8 no signal
609 Staphylococcal Infection 43 1.8 1.8 no signal
610 Secretion Discharge 16 1.8 1.8 no signal
611 Faeces Discoloured 28 1.8 1.8 no signal
612 Treatment Failure 106 1.8 1.8 no signal
613 Product Use Complaint 20 1.8 1.8 no signal
614 Poisoning Deliberate 12 1.8 1.8 no signal
615 Circulatory Collapse 22 1.8 1.8 no signal
616 Product Substitution Issue 74 1.8 1.8 no signal
617 Hepatic Cirrhosis 24 1.8 1.8 no signal
618 Dyspnoea 726 1.8 1.8 no signal
619 Musculoskeletal Discomfort 22 1.8 1.8 no signal
620 Eyelid Ptosis 13 1.8 1.8 no signal
621 Arthralgia 528 1.8 1.8 no signal
622 Respiratory Tract Infection 33 1.8 1.8 no signal
623 Immunosuppression 11 1.7 1.7 no signal
624 Drug Withdrawal Syndrome 112 1.7 1.7 no signal
625 Respiratory Failure 92 1.7 1.7 no signal
626 Accident 15 1.7 1.7 no signal
627 Respiratory Tract Congestion 20 1.7 1.7 no signal
628 Supraventricular Tachycardia 12 1.7 1.7 no signal
629 Fear 34 1.7 1.7 no signal
630 Hyperlipidaemia 15 1.7 1.7 no signal
631 Multiple Sclerosis 60 1.7 1.7 no signal
632 Blood Pressure Increased 191 1.7 1.7 no signal
633 Therapy Change 12 1.7 1.7 no signal
634 Type 2 Diabetes Mellitus 42 1.7 1.7 no signal
635 Weight Increased 277 1.7 1.7 no signal
636 Bacterial Infection 23 1.7 1.7 no signal
637 Seizure 142 1.7 1.7 no signal
638 Status Epilepticus 14 1.7 1.7 no signal
639 Gastrointestinal Disorder 109 1.7 1.7 no signal
640 Renal Injury 37 1.7 1.7 no signal
641 Mental Status Changes 34 1.7 1.7 no signal
642 Internal Haemorrhage 14 1.7 1.7 no signal
643 Generalised Tonic-clonic Seizure 20 1.7 1.7 no signal
644 Inability To Afford Medication 12 1.7 1.7 no signal
645 Cholelithiasis 40 1.7 1.7 no signal
646 Fluid Overload 18 1.7 1.7 no signal
647 Herpes Zoster 70 1.7 1.7 no signal
648 Haematochezia 67 1.7 1.7 no signal
649 Nasal Congestion 71 1.7 1.7 no signal
650 Complication Associated With Device 16 1.7 1.7 no signal
651 Cardiac Failure 97 1.7 1.7 no signal
652 Accidental Overdose 44 1.7 1.7 no signal
653 Haematocrit Decreased 24 1.7 1.7 no signal
654 Sinus Tachycardia 17 1.7 1.7 no signal
655 Candida Infection 20 1.7 1.7 no signal
656 Musculoskeletal Pain 63 1.6 1.6 no signal
657 Abscess 19 1.6 1.6 no signal
658 Cold Sweat 21 1.6 1.6 no signal
659 Bacteraemia 14 1.6 1.6 no signal
660 Product Use Issue 222 1.6 1.6 no signal
661 Septic Shock 51 1.6 1.6 no signal
662 Osteopenia 18 1.6 1.6 no signal
663 Mood Altered 32 1.6 1.6 no signal
664 Hemiparesis 20 1.6 1.6 no signal
665 Syncope 117 1.6 1.6 no signal
666 Sinusitis 120 1.6 1.6 no signal
667 Nerve Injury 13 1.6 1.6 no signal
668 Hyperkalaemia 40 1.6 1.6 no signal
669 Encephalopathy 28 1.6 1.6 no signal
670 Bone Disorder 21 1.6 1.6 no signal
671 Intentional Product Misuse 99 1.6 1.6 no signal
672 Heart Rate Increased 112 1.6 1.6 no signal
673 Drug Ineffective For Unapproved Indication 63 1.6 1.6 no signal
674 Nervousness 59 1.5 1.5 no signal
675 Dermatitis Allergic 14 1.5 1.5 no signal
676 Joint Range Of Motion Decreased 15 1.5 1.5 no signal
677 Kidney Infection 22 1.5 1.5 no signal
678 Psoriatic Arthropathy 45 1.5 1.5 no signal
679 Decreased Appetite 259 1.5 1.5 no signal
680 Dehydration 149 1.5 1.5 no signal
681 Sensory Disturbance 18 1.5 1.5 no signal
682 Vertigo 68 1.5 1.5 no signal
683 Hepatomegaly 11 1.5 1.5 no signal
684 Pharyngitis Streptococcal 12 1.5 1.5 no signal
685 Body Temperature Decreased 11 1.5 1.5 no signal
686 Metabolic Acidosis 35 1.5 1.5 no signal
687 Joint Stiffness 29 1.5 1.5 no signal
688 Product Physical Issue 22 1.5 1.5 no signal
689 Paraesthesia 174 1.5 1.5 no signal
690 Economic Problem 17 1.5 1.5 no signal
691 Swelling 103 1.5 1.5 no signal
692 Nausea 870 1.5 1.5 no signal
693 Product Administration Error 22 1.5 1.5 no signal
694 Haematemesis 28 1.5 1.5 no signal
695 Covid-19 193 1.5 1.5 no signal
696 Glaucoma 21 1.5 1.5 no signal
697 Skin Discolouration 50 1.5 1.5 no signal
698 Dental Caries 12 1.5 1.5 no signal
699 Increased Tendency To Bruise 10 1.5 1.5 no signal
700 Hypomagnesaemia 15 1.5 1.5 no signal
701 Drug Ineffective 1,422 1.5 1.5 no signal
702 Pulmonary Embolism 103 1.5 1.5 no signal
703 Drug Prescribing Error 21 1.5 1.5 no signal
704 Insurance Issue 16 1.5 1.5 no signal
705 Glomerular Filtration Rate Decreased 13 1.5 1.5 no signal
706 Hypothyroidism 34 1.5 1.5 no signal
707 Abdominal Pain Upper 219 1.5 1.5 no signal
708 Poor Venous Access 11 1.5 1.5 no signal
709 Abdominal Discomfort 178 1.5 1.5 no signal
710 Cataract 63 1.5 1.5 no signal
711 Flatulence 60 1.5 1.5 no signal
712 Small Intestinal Obstruction 13 1.5 1.5 no signal
713 Sinus Disorder 21 1.5 1.5 no signal
714 Product Dose Omission 70 1.5 1.5 no signal
715 Fracture 20 1.5 1.5 no signal
716 Oedema 57 1.4 1.5 no signal
717 Fungal Infection 35 1.4 1.4 no signal
718 Hospitalisation 160 1.4 1.5 no signal
719 Respiratory Distress 29 1.4 1.4 no signal
720 Procedural Pain 29 1.4 1.4 no signal
721 Infection 151 1.4 1.4 no signal
722 Transfusion 11 1.4 1.4 no signal
723 Intestinal Obstruction 39 1.4 1.4 no signal
724 Gastric Haemorrhage 12 1.4 1.4 no signal
725 Nasopharyngitis 191 1.4 1.4 no signal
726 Ankle Fracture 16 1.4 1.4 no signal
727 Drug Effect Incomplete 38 1.4 1.4 no signal
728 Abdominal Distension 107 1.4 1.4 no signal
729 Sneezing 23 1.4 1.4 no signal
730 Sexual Dysfunction 12 1.4 1.4 no signal
731 Unintentional Medical Device Removal 12 1.4 1.4 no signal
732 Spinal Pain 12 1.4 1.4 no signal
733 Swollen Tongue 32 1.4 1.4 no signal
734 Completed Suicide 86 1.4 1.4 no signal
735 Influenza 114 1.4 1.4 no signal
736 Body Height Decreased 11 1.4 1.4 no signal
737 Atrial Fibrillation 99 1.4 1.4 no signal
738 Mydriasis 13 1.4 1.4 no signal
739 Cardiac Disorder 95 1.4 1.4 no signal
740 Lethargy 58 1.4 1.4 no signal
741 Gastrointestinal Pain 11 1.4 1.4 no signal
742 Mood Swings 32 1.4 1.4 no signal
743 Throat Tightness 27 1.4 1.4 no signal
744 Product Use In Unapproved Indication 244 1.4 1.4 no signal
745 Illness 100 1.4 1.4 no signal
746 Osteomyelitis 18 1.4 1.4 no signal
747 Headache 621 1.4 1.4 no signal
748 Scar 17 1.4 1.4 no signal
749 Malnutrition 11 1.4 1.4 no signal
750 Muscle Tightness 16 1.4 1.4 no signal
751 Drug Effect Decreased 54 1.4 1.4 no signal
752 Vomiting 463 1.4 1.4 no signal
753 Hypertensive Crisis 11 1.4 1.4 no signal
754 Malaise 431 1.3 1.4 no signal
755 Temperature Intolerance 10 1.3 1.3 no signal
756 Intestinal Perforation 11 1.3 1.3 no signal
757 Red Blood Cell Count Decreased 28 1.3 1.3 no signal
758 Bronchospasm 14 1.3 1.3 no signal
759 Diverticulitis 27 1.3 1.3 no signal
760 Ileus 12 1.3 1.3 no signal
761 Thyroid Disorder 15 1.3 1.3 no signal
762 Libido Decreased 12 1.3 1.3 no signal
763 Renal Impairment 81 1.3 1.3 no signal
764 Femur Fracture 30 1.3 1.3 no signal
765 Scratch 10 1.3 1.3 no signal
766 Anosmia 14 1.3 1.3 no signal
767 Hepatic Encephalopathy 9 1.3 1.3 no signal
768 Hair Texture Abnormal 13 1.3 1.3 no signal
769 Intentional Overdose 61 1.3 1.3 no signal
770 Tachycardia 85 1.3 1.3 no signal
771 Therapy Interrupted 66 1.3 1.3 no signal
772 Device Difficult To Use 63 1.3 1.3 no signal
773 Immunodeficiency 14 1.3 1.3 no signal
774 Blood Urea Increased 16 1.3 1.3 no signal
775 Eye Disorder 31 1.3 1.3 no signal
776 Renal Disorder 44 1.3 1.3 no signal
777 Leukocytosis 17 1.3 1.3 no signal
778 Pharyngeal Swelling 9 1.3 1.3 no signal
779 Rhabdomyolysis 39 1.3 1.3 no signal
780 Myalgia 159 1.3 1.3 no signal
781 Haemoglobin Decreased 96 1.3 1.3 no signal
782 Aphonia 13 1.3 1.3 no signal
783 Neuropathy Peripheral 88 1.3 1.3 no signal
784 Thrombotic Microangiopathy 9 1.3 1.3 no signal
785 Blister 52 1.3 1.3 no signal
786 Ear Pain 18 1.3 1.3 no signal
787 Heart Rate Irregular 21 1.3 1.3 no signal
788 Osteoporosis 38 1.3 1.3 no signal
789 Laryngitis 10 1.3 1.3 no signal
790 Erythema 189 1.3 1.3 no signal
791 Pulmonary Oedema 41 1.3 1.3 no signal
792 Diabetes Mellitus 70 1.3 1.3 no signal
793 Feeling Hot 56 1.3 1.3 no signal
794 Dry Eye 44 1.3 1.3 no signal
795 Abdominal Pain Lower 23 1.2 1.2 no signal
796 Subdural Haematoma 13 1.2 1.2 no signal
797 Rash Maculo-papular 20 1.2 1.2 no signal
798 Skin Haemorrhage 13 1.2 1.2 no signal
799 Adverse Event 83 1.2 1.2 no signal
800 Off Label Use 781 1.2 1.3 no signal
801 Ventricular Fibrillation 10 1.2 1.2 no signal
802 Toxic Skin Eruption 9 1.2 1.2 no signal
803 Lower Limb Fracture 17 1.2 1.2 no signal
804 Upper Gastrointestinal Haemorrhage 15 1.2 1.2 no signal
805 Blood Calcium Decreased 10 1.2 1.2 no signal
806 Coronary Artery Disease 27 1.2 1.2 no signal
807 Dermatitis Contact 10 1.2 1.2 no signal
808 Cholecystectomy 10 1.2 1.2 no signal
809 Pallor 24 1.2 1.2 no signal
810 Extra Dose Administered 35 1.2 1.2 no signal
811 Cardiac Failure Congestive 71 1.2 1.2 no signal
812 Device Leakage 37 1.2 1.2 no signal
813 Chest Discomfort 89 1.2 1.2 no signal
814 Haemorrhoids 17 1.2 1.2 no signal
815 Dysuria 32 1.2 1.2 no signal
816 Gastrointestinal Haemorrhage 73 1.2 1.2 no signal
817 Neoplasm 10 1.2 1.2 no signal
818 Alopecia 170 1.2 1.2 no signal
819 Hypoaesthesia Oral 13 1.2 1.2 no signal
820 Melaena 19 1.2 1.2 no signal
821 Hypersensitivity 159 1.2 1.2 no signal
822 Gamma-glutamyltransferase Increased 19 1.2 1.2 no signal
823 Dyspepsia 84 1.2 1.2 no signal
824 Liver Function Test Abnormal 25 1.2 1.2 no signal
825 Splenomegaly 10 1.2 1.2 no signal
826 Nephropathy 8 1.2 1.2 no signal
827 Tooth Disorder 19 1.2 1.2 no signal
828 Activities Of Daily Living Impaired 17 1.2 1.2 no signal
829 Oral Candidiasis 11 1.2 1.2 no signal
830 Drug Level Increased 14 1.2 1.2 no signal
831 Acute Myocardial Infarction 25 1.2 1.2 no signal
832 Chest Pain 156 1.2 1.2 no signal
833 Device Breakage 33 1.2 1.2 no signal
834 Night Sweats 27 1.2 1.2 no signal
835 Gastritis 22 1.2 1.2 no signal
836 Electrocardiogram Qt Prolonged 30 1.1 1.1 no signal
837 Angina Pectoris 24 1.1 1.1 no signal
838 Inappropriate Schedule Of Product Administration 147 1.1 1.1 no signal
839 Pulmonary Congestion 11 1.1 1.1 no signal
840 Schizophrenia 10 1.1 1.1 no signal
841 Cardiovascular Disorder 21 1.1 1.1 no signal
842 Blood Glucose Fluctuation 9 1.1 1.1 no signal
843 Skin Disorder 27 1.1 1.1 no signal
844 Blindness 33 1.1 1.1 no signal
845 Drug-induced Liver Injury 25 1.1 1.1 no signal
846 Mouth Ulceration 17 1.1 1.1 no signal
847 Eye Infection 9 1.1 1.1 no signal
848 Migraine 76 1.1 1.1 no signal
849 Chills 94 1.1 1.1 no signal
850 Taste Disorder 16 1.1 1.1 no signal
851 Colitis 30 1.1 1.1 no signal
852 Hair Colour Changes 10 1.1 1.1 no signal
853 Skin Fissures 15 1.1 1.1 no signal
854 Incorrect Product Administration Duration 16 1.1 1.1 no signal
855 Vision Blurred 107 1.1 1.1 no signal
856 Gallbladder Disorder 14 1.1 1.1 no signal
857 Body Temperature Increased 16 1.1 1.1 no signal
858 Diarrhoea 502 1.1 1.1 no signal
859 White Blood Cell Count Increased 30 1.1 1.1 no signal
860 Pain In Jaw 22 1.1 1.1 no signal
861 Rash Macular 27 1.1 1.1 no signal
862 Anger 26 1.1 1.1 no signal
863 Paralysis 11 1.1 1.1 no signal
864 Blood Thyroid Stimulating Hormone Increased 7 1.0 1.0 no signal
865 Agranulocytosis 14 1.0 1.0 no signal
866 Pyrexia 262 1.0 1.0 no signal
867 Macular Degeneration 9 1.0 1.0 no signal
868 Drug Abuse 63 1.0 1.0 no signal
869 Appendicitis 7 1.0 1.0 no signal
870 Gastric Disorder 26 1.0 1.0 no signal
871 Pruritus 282 1.0 1.0 no signal
872 Impaired Work Ability 16 1.0 1.0 no signal
873 Hunger 10 1.0 1.0 no signal
874 Product Taste Abnormal 10 1.0 1.0 no signal
875 Thyroid Cancer 9 1.0 1.0 no signal
876 Sinus Congestion 10 1.0 1.0 no signal
877 Lacrimation Increased 22 1.0 1.0 no signal
878 Injection Site Pruritus 49 1.0 1.0 no signal
879 Product Dispensing Error 16 1.0 1.0 no signal
880 Acute Hepatic Failure 10 1.0 1.0 no signal
881 Respiratory Depression 9 1.0 1.0 no signal
882 Laceration 7 1.0 1.0 no signal
883 Thrombosis 59 1.0 1.0 no signal
884 Ischaemic Stroke 13 1.0 1.0 no signal
885 Burning Sensation 51 1.0 1.0 no signal
886 Toxicity To Various Agents 122 1.0 1.0 no signal
887 Palpitations 85 1.0 1.0 no signal
888 Blood Alkaline Phosphatase Increased 18 1.0 1.0 no signal
889 Expired Product Administered 24 1.0 1.0 no signal
890 Application Site Irritation 9 1.0 1.0 no signal
891 Vitreous Floaters 7 1.0 1.0 no signal
892 Extrapyramidal Disorder 18 1.0 1.0 no signal
893 Thrombocytopenia 80 1.0 1.0 no signal
894 Bone Pain 42 1.0 1.0 no signal
895 Ear Infection 19 1.0 1.0 no signal
896 Device Related Infection 11 1.0 1.0 no signal
897 Brain Oedema 9 1.0 1.0 no signal
898 Injection Site Irritation 9 1.0 1.0 no signal
899 Discomfort 43 1.0 1.0 no signal
900 Chromaturia 16 1.0 1.0 no signal
901 Ejection Fraction Decreased 11 1.0 1.0 no signal
902 Death 606 1.0 1.0 no signal
903 Dependence 39 1.0 1.0 no signal
904 Oropharyngeal Pain 65 1.0 1.0 no signal
905 Rhinorrhoea 45 1.0 1.0 no signal
906 Hypotonia 7 1.0 1.0 no signal
907 Psoriasis 91 1.0 1.0 no signal
908 Cerebral Infarction 17 1.0 1.0 no signal
909 Coma 33 1.0 1.0 no signal
910 Rash 300 1.0 1.0 no signal
911 Cardio-respiratory Arrest 29 0.9 0.9 no signal
912 Product Prescribing Issue 14 0.9 0.9 no signal
913 Pulmonary Arterial Hypertension 10 0.9 0.9 no signal
914 Drug Level Decreased 7 0.9 0.9 no signal
915 Ear Discomfort 7 0.9 0.9 no signal
916 Cerebrovascular Accident 116 0.9 0.9 no signal
917 Injection Site Mass 25 0.9 0.9 no signal
918 Injection Site Discomfort 7 0.9 0.9 no signal
919 Blood Potassium Increased 11 0.9 0.9 no signal
920 Lymphadenopathy 24 0.9 0.9 no signal
921 Liver Disorder 30 0.9 0.9 no signal
922 Peritonitis 14 0.9 0.9 no signal
923 Weight Fluctuation 7 0.9 0.9 no signal
924 Disease Recurrence 32 0.9 0.9 no signal
925 Nervous System Disorder 21 0.9 0.9 no signal
926 Tenderness 7 0.9 0.9 no signal
927 Colon Cancer 10 0.9 0.9 no signal
928 Acne 51 0.9 0.9 no signal
929 Gastroenteritis Viral 12 0.9 0.9 no signal
930 Lip Swelling 22 0.9 0.9 no signal
931 Leukopenia 33 0.9 0.9 no signal
932 Application Site Pruritus 15 0.9 0.9 no signal
933 Haemorrhage 69 0.9 0.9 no signal
934 Ill-defined Disorder 40 0.9 0.9 no signal
935 Hepatitis C 8 0.9 0.9 no signal
936 Wrong Technique In Product Usage Process 132 0.9 0.9 no signal
937 Device Delivery System Issue 17 0.9 0.9 no signal
938 Emotional Distress 79 0.9 0.9 no signal
939 Oral Discomfort 9 0.9 0.9 no signal
940 Erythema Multiforme 6 0.9 0.9 no signal
941 Tooth Extraction 8 0.9 0.9 no signal
942 Osteonecrosis Of Jaw 16 0.9 0.9 no signal
943 Oesophagitis 7 0.9 0.9 no signal
944 Cardiac Arrest 53 0.9 0.9 no signal
945 Blindness Unilateral 9 0.9 0.9 no signal
946 Pruritus Generalised 14 0.9 0.9 no signal
947 Arteriosclerosis 6 0.9 0.9 no signal
948 Frequent Bowel Movements 17 0.9 0.9 no signal
949 Blood Urine Present 12 0.9 0.9 no signal
950 Eosinophilia 11 0.9 0.9 no signal
951 Pancreatitis Acute 14 0.9 0.9 no signal
952 Blood Lactate Dehydrogenase Increased 10 0.9 0.9 no signal
953 Rectal Haemorrhage 27 0.9 0.9 no signal
954 Blood Glucose Decreased 30 0.9 0.9 no signal
955 Local Swelling 11 0.9 0.9 no signal
956 Fistula 7 0.9 0.9 no signal
957 Rebound Effect 7 0.8 0.8 no signal
958 Neoplasm Malignant 41 0.8 0.8 no signal
959 Ascites 18 0.8 0.8 no signal
960 Tinnitus 28 0.8 0.8 no signal
961 Immune System Disorder 8 0.8 0.8 no signal
962 Photosensitivity Reaction 10 0.8 0.8 no signal
963 Respiratory Disorder 18 0.8 0.8 no signal
964 Therapy Partial Responder 9 0.8 0.8 no signal
965 Caesarean Section 7 0.8 0.8 no signal
966 Lactic Acidosis 19 0.8 0.8 no signal
967 Covid-19 Pneumonia 7 0.8 0.8 no signal
968 Arrhythmia 28 0.8 0.8 no signal
969 Subarachnoid Haemorrhage 6 0.8 0.8 no signal
970 Cerebral Haemorrhage 21 0.8 0.8 no signal
971 Epistaxis 44 0.8 0.8 no signal
972 Disease Progression 69 0.8 0.8 no signal
973 Drug Dose Omission 98 0.8 0.8 no signal
974 Product Preparation Error 12 0.8 0.8 no signal
975 Tendonitis 9 0.8 0.8 no signal
976 Foetal Exposure During Pregnancy 47 0.8 0.8 no signal
977 Acute Myeloid Leukaemia 9 0.8 0.8 no signal
978 Respiratory Arrest 16 0.8 0.8 no signal
979 Tooth Loss 12 0.8 0.8 no signal
980 Skeletal Injury 6 0.8 0.8 no signal
981 Overdose 124 0.8 0.8 no signal
982 Lung Infection 9 0.8 0.8 no signal
983 Cyanosis 9 0.8 0.8 no signal
984 Pneumothorax 9 0.8 0.8 no signal
985 Pancreatitis 30 0.8 0.8 no signal
986 Myocardial Infarction 99 0.8 0.8 no signal
987 Hepatocellular Injury 8 0.8 0.8 no signal
988 Eye Pain 31 0.8 0.8 no signal
989 Thirst 10 0.8 0.8 no signal
990 Injection Site Extravasation 7 0.8 0.8 no signal
991 Inappropriate Schedule Of Drug Administration 40 0.8 0.8 no signal
992 Blood Bilirubin Increased 15 0.8 0.8 no signal
993 Swelling Face 36 0.8 0.8 no signal
994 Toothache 10 0.8 0.8 no signal
995 Incorrect Dose Administered By Device 14 0.8 0.8 no signal
996 Full Blood Count Decreased 11 0.8 0.8 no signal
997 Hypokalaemia 25 0.7 0.7 no signal
998 Dysgeusia 40 0.7 0.7 no signal
999 Diarrhoea Haemorrhagic 5 0.7 0.7 no signal
1000 Increased Appetite 10 0.7 0.7 no signal
1001 Hot Flush 40 0.7 0.7 no signal
1002 Hepatic Failure 16 0.7 0.7 no signal
1003 Tardive Dyskinesia 15 0.7 0.7 no signal
1004 Gastric Ulcer 10 0.7 0.7 no signal
1005 Epilepsy 16 0.7 0.7 no signal
1006 Autoimmune Disorder 5 0.7 0.7 no signal
1007 International Normalised Ratio Increased 15 0.7 0.7 no signal
1008 Neurotoxicity 9 0.7 0.7 no signal
1009 Eczema 26 0.7 0.7 no signal
1010 Glycosylated Haemoglobin Increased 13 0.7 0.7 no signal
1011 Irritable Bowel Syndrome 11 0.7 0.7 no signal
1012 Blood Cholesterol Increased 24 0.7 0.7 no signal
1013 Decreased Immune Responsiveness 5 0.7 0.7 no signal
1014 Incorrect Dose Administered 115 0.7 0.7 no signal
1015 Device Deployment Issue 6 0.7 0.7 no signal
1016 Hepatotoxicity 11 0.7 0.7 no signal
1017 Dialysis 7 0.7 0.7 no signal
1018 Eye Discharge 5 0.7 0.7 no signal
1019 Poor Quality Product Administered 5 0.7 0.7 no signal
1020 Paraesthesia Oral 7 0.7 0.7 no signal
1021 Eye Swelling 18 0.7 0.7 no signal
1022 Hyperbilirubinaemia 5 0.7 0.7 no signal
1023 Multiple Fractures 8 0.7 0.7 no signal
1024 Shock 11 0.7 0.7 no signal
1025 Coagulopathy 8 0.7 0.7 no signal
1026 Viral Infection 16 0.7 0.7 no signal
1027 Injury 34 0.7 0.7 no signal
1028 Wrong Technique In Device Usage Process 22 0.7 0.7 no signal
1029 Systemic Lupus Erythematosus 17 0.7 0.7 no signal
1030 Poisoning 6 0.7 0.7 no signal
1031 Cytokine Release Syndrome 9 0.6 0.6 no signal
1032 Influenza Like Illness 39 0.6 0.6 no signal
1033 Colitis Ulcerative 21 0.6 0.6 no signal
1034 Drug Resistance 12 0.6 0.6 no signal
1035 Oral Herpes 9 0.6 0.6 no signal
1036 Stomatitis 28 0.6 0.6 no signal
1037 Device Failure 7 0.6 0.6 no signal
1038 Platelet Count Increased 6 0.6 0.6 no signal
1039 Hand Deformity 6 0.6 0.6 no signal
1040 Metastases To Liver 8 0.6 0.6 no signal
1041 Adverse Reaction 6 0.6 0.6 no signal
1042 Blood Triglycerides Increased 8 0.6 0.6 no signal
1043 Incorrect Product Storage 6 0.6 0.6 no signal
1044 Drug Administration Error 14 0.6 0.6 no signal
1045 Jaundice 12 0.6 0.6 no signal
1046 Pneumonitis 12 0.6 0.6 no signal
1047 Hyperglycaemia 16 0.6 0.6 no signal
1048 Device Use Error 15 0.6 0.6 no signal
1049 Urticaria 73 0.6 0.6 no signal
1050 Myocardial Ischaemia 5 0.6 0.6 no signal
1051 Coronary Artery Occlusion 6 0.6 0.6 no signal
1052 Metastases To Lung 5 0.6 0.6 no signal
1053 Hepatic Function Abnormal 16 0.6 0.6 no signal
1054 Metastases To Bone 7 0.6 0.6 no signal
1055 Injection Site Erythema 52 0.6 0.6 no signal
1056 Eructation 8 0.6 0.6 no signal
1057 Cytopenia 5 0.6 0.6 no signal
1058 Application Site Erythema 11 0.6 0.6 no signal
1059 Diabetic Ketoacidosis 10 0.6 0.6 no signal
1060 Myelodysplastic Syndrome 6 0.6 0.6 no signal
1061 Flushing 42 0.6 0.6 no signal
1062 Skin Exfoliation 34 0.6 0.6 no signal
1063 Injection Site Swelling 31 0.6 0.6 no signal
1064 Haematuria 14 0.6 0.6 no signal
1065 Product Quality Issue 55 0.6 0.6 no signal
1066 No Therapeutic Response 5 0.6 0.6 no signal
1067 Injection Site Haemorrhage 32 0.6 0.6 no signal
1068 Device Malfunction 27 0.6 0.6 no signal
1069 Product Availability Issue 9 0.6 0.6 no signal
1070 Anaphylactic Reaction 22 0.6 0.6 no signal
1071 Haemorrhage Intracranial 6 0.6 0.5 no signal
1072 Ovarian Cyst 4 0.5 0.5 no signal
1073 Eye Irritation 22 0.5 0.5 no signal
1074 Drug Reaction With Eosinophilia And Systemic Symptoms 10 0.5 0.5 no signal
1075 Blood Count Abnormal 6 0.5 0.5 no signal
1076 Injection Site Warmth 8 0.5 0.5 no signal
1077 Visual Acuity Reduced 13 0.5 0.5 no signal
1078 Exposure During Pregnancy 24 0.5 0.5 no signal
1079 Injection Site Induration 5 0.5 0.5 no signal
1080 Ocular Hyperaemia 18 0.5 0.5 no signal
1081 Rash Erythematous 18 0.5 0.5 no signal
1082 Plasma Cell Myeloma 15 0.5 0.5 no signal
1083 Hereditary Angioedema 4 0.5 0.5 no signal
1084 Blood Glucose Increased 72 0.5 0.5 no signal
1085 Injection Site Bruising 30 0.5 0.5 no signal
1086 Blood Glucose Abnormal 7 0.5 0.5 no signal
1087 Renal Failure Acute 16 0.5 0.5 no signal
1088 Sleep Disorder Due To A General Medical Condition 6 0.5 0.5 no signal
1089 Product Adhesion Issue 13 0.5 0.5 no signal
1090 Product Packaging Quantity Issue 4 0.5 0.5 no signal
1091 Osteonecrosis 12 0.5 0.5 no signal
1092 Prostatic Specific Antigen Increased 5 0.5 0.5 no signal
1093 Nephropathy Toxic 4 0.5 0.5 no signal
1094 Menorrhagia 7 0.5 0.5 no signal
1095 Incorrect Drug Administration Duration 10 0.5 0.5 no signal
1096 Dry Skin 46 0.5 0.5 no signal
1097 Pancreatic Carcinoma 10 0.5 0.5 no signal
1098 Pain Of Skin 9 0.5 0.5 no signal
1099 Product Packaging Issue 3 0.4 0.4 no signal
1100 Drug Dispensing Error 5 0.4 0.4 no signal
1101 Injection Site Discolouration 4 0.4 0.4 no signal
1102 White Blood Cell Count Decreased 35 0.4 0.4 no signal
1103 Leukaemia 3 0.4 0.4 no signal
1104 Injection Site Pain 96 0.4 0.4 no signal
1105 Needle Issue 9 0.4 0.4 no signal
1106 Premature Delivery 5 0.4 0.4 no signal
1107 Interstitial Lung Disease 15 0.4 0.4 no signal
1108 Skin Burning Sensation 22 0.4 0.4 no signal
1109 Device Defective 5 0.4 0.4 no signal
1110 Deep Vein Thrombosis 20 0.4 0.4 no signal
1111 Injection Site Reaction 21 0.4 0.4 no signal
1112 Coeliac Disease 3 0.4 0.4 no signal
1113 Vaginal Discharge 3 0.4 0.4 no signal
1114 Injection Site Rash 9 0.4 0.4 no signal
1115 Drug Dependence 48 0.4 0.4 no signal
1116 Angioedema 13 0.4 0.4 no signal
1117 Lung Neoplasm Malignant 12 0.4 0.4 no signal
1118 Application Site Rash 4 0.4 0.4 no signal
1119 Injection Site Urticaria 7 0.4 0.4 no signal
1120 Breast Pain 3 0.4 0.4 no signal
1121 Neutropenia 38 0.4 0.4 no signal
1122 Dermatitis Atopic 14 0.4 0.4 no signal
1123 Breast Cancer Metastatic 3 0.4 0.4 no signal
1124 Pelvic Pain 5 0.4 0.4 no signal
1125 Meningioma 4 0.4 0.4 no signal
1126 Circumstance Or Information Capable Of Leading To Medication Error 9 0.4 0.4 no signal
1127 Platelet Count Decreased 28 0.4 0.4 no signal
1128 Bone Density Decreased 8 0.3 0.3 no signal
1129 Febrile Neutropenia 16 0.3 0.3 no signal
1130 Pemphigus 3 0.3 0.3 no signal
1131 Vaginal Haemorrhage 10 0.3 0.3 no signal
1132 Prostate Cancer 19 0.3 0.3 no signal
1133 Pancytopenia 13 0.3 0.3 no signal
1134 Tuberculosis 3 0.3 0.3 no signal
1135 Device Expulsion 15 0.3 0.3 no signal
1136 Application Site Pain 5 0.3 0.3 no signal
1137 Exposure Via Skin Contact 5 0.3 0.3 no signal
1138 No Adverse Event 39 0.3 0.3 no signal
1139 Palmar-plantar Erythrodysaesthesia Syndrome 5 0.3 0.3 no signal
1140 Maternal Exposure During Pregnancy 17 0.3 0.3 no signal
1141 Wrong Technique In Drug Usage Process 7 0.3 0.3 no signal
1142 Sickle Cell Anaemia With Crisis 3 0.3 0.3 no signal
1143 Breast Cancer Female 5 0.3 0.3 no signal
1144 Skin Irritation 8 0.2 0.2 no signal
1145 Bladder Cancer 10 0.2 0.2 no signal
1146 Oesophageal Carcinoma 5 0.2 0.2 no signal
1147 Complication Of Device Insertion 3 0.2 0.2 no signal
1148 Gynaecomastia 5 0.2 0.2 no signal
1149 Breast Cancer 15 0.2 0.2 no signal
1150 Intentional Drug Misuse 3 0.2 0.2 no signal
1151 Product Storage Error 12 0.2 0.2 no signal
1152 Malignant Neoplasm Progression 14 0.2 0.2 no signal
1153 Hepatic Cancer 3 0.2 0.2 no signal
1154 Product Complaint 3 0.2 0.2 no signal
1155 Accidental Exposure To Product 12 0.2 0.2 no signal
1156 Incorrect Route Of Drug Administration 4 0.2 0.2 no signal
1157 Drug Dose Omission By Device 7 0.1 0.1 no signal
1158 Renal Cancer 3 0.1 0.1 no signal