Reaction

Freezing Phenomenon reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 3,550 reports · 46 co-occurring drugs

As of the last recalculation, Freezing Phenomenon appears in 3,550 FAERS reports alongside 46 co-occurring drug terms. The strongest observed disproportionality signal is CARBIDOPA AND LEVODOPA (PRR 153.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Carbidopa And Levodopa	922	153.6	156.6
Rasagiline Mesylate	204	113.9	116.1
Amantadine	270	110.7	112.6
Levodopa	197	101.1	102.8
Pramipexole	234	95.8	97.3
Rotigotine	202	86.8	88.0
Rivastigmine	246	82.2	83.3
Ropinirole	166	66.5	67.2
Pimavanserin Tartrate	184	20.5	20.6
Droxidopa	48	13.2	13.2
Memantine	26	11.2	11.2
Memantine Hydrochloride	26	11.2	11.2
Oxazepam	40	11.0	11.0
Melatonin	98	10.8	10.8
Clozapine	212	10.5	10.5
Donepezil Hydrochloride	60	9.7	9.7
Mirabegron	62	9.5	9.6
Dutasteride	12	8.7	8.7
Senna	28	7.8	7.9
Quetiapine	237	7.7	7.7
Sennosides 8.6 Mg Tablets	27	7.6	7.6
Standardized Senna Concentrate	16	7.5	7.5
Lactulose	48	7.4	7.4
Senna Leaf	29	7.4	7.4
Mirtazapine	105	6.9	6.9
Bisacodyl Suppositories	15	6.8	6.8
Biscodyl	15	6.8	6.8
Bisacodyl	15	6.3	6.3
Clonazepam	160	6.1	6.1
Sennosides	30	5.9	5.9
Cyanocobalamin	32	5.7	5.7
Drs. Clotrimazole	11	5.6	5.6
Family Wellness Clotrimazole	11	5.6	5.6
Clotrimazole Topical	11	5.6	5.6
Clotrimazole	11	5.3	5.3
Lubiprostone	8	5.0	5.0
Psyllium Husk	8	4.8	4.8
Escitslopram	45	4.6	4.6
Oxybutynin	21	4.2	4.2
Escitalopram Oxalate	51	4.1	4.1
Tamsulosin Hydrochloride	13	3.7	3.7
Polyethylene Glycol 3350	55	3.4	3.4
Fesoterodine Fumarate	6	3.3	3.3
Linaclotide	14	3.1	3.1
Brinzolamide	4	2.7	2.7
Canagliflozin	8	1.6	1.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.