OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Theophylline Anhydrous

1,156 flagged reaction(s) · 72,255 total co-reports · max PRR 19,797.8
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Amyloid Arthropathy 59 19,797.8 19,893.1 signal
2 Right Atrial Hypertrophy 88 6,711.1 6,759.4 signal
3 Antasthmatic Drug Level Above Therapeutic 17 4,074.6 4,080.2 signal
4 Heart Sounds 61 2,924.1 2,938.7 signal
5 Decreased Bronchial Secretion 15 1,094.2 1,095.5 signal
6 Antacid Therapy 44 984.3 987.8 signal
7 Occupational Asthma 21 952.3 953.9 signal
8 Bronchial Neoplasm 46 867.2 870.4 signal
9 Rhinitis Perennial 26 807.8 809.5 signal
10 Sleep Disorder Therapy 53 678.8 681.7 signal
11 Prolonged Expiration 62 522.7 525.4 signal
12 Product Administration Issue 18 511.9 512.6 signal
13 Analgesic Therapy 60 414.3 416.3 signal
14 Adulterated Product 34 365.7 366.7 signal
15 Appendicolith 67 365.0 367.0 signal
16 Drug Therapy 56 361.4 363.0 signal
17 Bronchial Haemorrhage 49 313.8 315.0 signal
18 Anticoagulant Therapy 41 295.2 296.2 signal
19 Bronchial Wall Thickening 98 266.1 268.2 signal
20 Nasal Oedema 237 259.4 264.4 signal
21 Endometrial Ablation 45 247.5 248.4 signal
22 Nasal Turbinate Hypertrophy 47 243.4 244.3 signal
23 Vital Capacity Decreased 45 188.8 189.4 signal
24 Right Ventricular Hypertrophy 88 182.1 183.4 signal
25 Airway Peak Pressure Increased 14 172.7 172.9 signal
26 Intubation 22 162.6 162.9 signal
27 Reversible Airways Obstruction 41 147.3 147.8 signal
28 Bronchial Secretion Retention 97 141.4 142.5 signal
29 Oligoarthritis 15 141.4 141.6 signal
30 Malignant Melanoma Stage 0 13 131.4 131.5 signal
31 Chronic Obstructive Airways Disease Exacerbated 25 130.7 130.9 signal
32 Status Asthmaticus 33 126.1 126.5 signal
33 Congenital Hiatus Hernia 15 123.4 123.5 signal
34 Pulmonary Function Test Abnormal 90 104.0 104.8 signal
35 Breast Conserving Surgery 29 102.2 102.5 signal
36 Aortic Valve Stenosis 98 98.6 99.4 signal
37 Nikolsky's Sign 10 98.1 98.2 signal
38 Trisomy 18 20 93.5 93.6 signal
39 Rhonchi 71 91.8 92.4 signal
40 Oesophageal Dilatation 21 85.9 86.1 signal
41 Bronchopulmonary Aspergillosis Allergic 41 79.6 79.9 signal
42 Female Sterilisation 19 65.2 65.3 signal
43 Total Lung Capacity Abnormal 14 64.9 65.0 signal
44 Lung Hyperinflation 31 63.3 63.4 signal
45 Epidural Lipomatosis 12 60.6 60.7 signal
46 Bronchial Obstruction 47 58.8 59.0 signal
47 Weaning Failure 12 58.2 58.2 signal
48 Forced Expiratory Volume Decreased 91 56.4 56.8 signal
49 Pulmonary Artery Dilatation 11 55.8 55.8 signal
50 Hyperphosphataemia 67 55.5 55.8 signal
51 Bronchial Disorder 49 55.2 55.4 signal
52 Obstruction 124 54.4 55.0 signal
53 Urinary Tract Discomfort 14 54.2 54.3 signal
54 Pco2 Increased 22 53.8 53.9 signal
55 Alveolar Osteitis 13 53.5 53.5 signal
56 Diastolic Dysfunction 94 53.1 53.5 signal
57 Chest X-ray Abnormal 93 52.6 53.0 signal
58 Adjustment Disorder 38 51.0 51.2 signal
59 Pulmonary Pain 78 47.5 47.8 signal
60 Allergic Granulomatous Angiitis 22 46.2 46.3 signal
61 Forced Vital Capacity Decreased 17 45.8 45.8 signal
62 Mental Disability 15 45.3 45.3 signal
63 Total Lung Capacity Decreased 41 44.7 44.8 signal
64 Obstructive Airways Disorder 284 44.4 45.4 signal
65 Rales 145 43.5 44.1 signal
66 Lung Opacity 62 42.0 42.2 signal
67 Wheezing 1,418 41.8 47.1 signal
68 Blood Phosphorus Increased 65 41.5 41.8 signal
69 Infective Exacerbation Of Chronic Obstructive Airways Disease 15 40.6 40.6 signal
70 Full Blood Count Abnormal 245 40.5 41.3 signal
71 Dyspnoea Exacerbated 12 40.0 40.1 signal
72 Febrile Convulsion 27 38.6 38.7 signal
73 Benign Prostatic Hyperplasia 115 38.6 39.0 signal
74 Breath Sounds Abnormal 108 38.1 38.4 signal
75 Foetal Malformation 23 36.5 36.5 signal
76 Dilated Cardiomyopathy 19 35.5 35.6 signal
77 Bronchiectasis 136 35.4 35.8 signal
78 Accidental Death 37 34.6 34.7 signal
79 Sputum Abnormal 13 34.5 34.5 signal
80 Sputum Retention 19 33.7 33.7 signal
81 Stress Urinary Incontinence 21 33.5 33.6 signal
82 Hypercapnia 57 33.0 33.2 signal
83 Oropharyngeal Candidiasis 17 32.7 32.7 signal
84 Asthma 2,100 32.5 38.9 signal
85 Allergic Cough 14 31.4 31.5 signal
86 Po2 Decreased 21 31.4 31.5 signal
87 Depressive Symptom 63 31.0 31.2 signal
88 Perfume Sensitivity 10 31.0 31.0 signal
89 Aortic Stenosis 60 29.8 29.9 signal
90 Respiratory Tract Infection 440 29.3 30.4 signal
91 Increased Viscosity Of Bronchial Secretion 10 27.3 27.3 signal
92 Bronchitis Chronic 38 26.7 26.8 signal
93 Sputum Discoloured 146 26.7 27.0 signal
94 Blood Immunoglobulin E Increased 37 26.2 26.3 signal
95 Sleep Disorder Due To A General Medical Condition 244 26.0 26.6 signal
96 Eosinophil Count Abnormal 11 25.5 25.5 signal
97 Animal Scratch 14 24.9 24.9 signal
98 Multiple Drug Therapy 10 24.7 24.7 signal
99 Oedema 770 24.5 26.1 signal
100 Granuloma 49 24.4 24.5 signal
101 Staphylococcus Test Positive 30 24.4 24.4 signal
102 Sinus Pain 32 23.9 24.0 signal
103 Sepsis Neonatal 11 23.6 23.6 signal
104 Dyspnoea Paroxysmal Nocturnal 10 23.4 23.4 signal
105 Dizziness Exertional 10 23.2 23.2 signal
106 Blood Ph Decreased 23 23.0 23.1 signal
107 Chronic Obstructive Pulmonary Disease 661 21.8 23.0 signal
108 Blood Bicarbonate Decreased 24 21.6 21.7 signal
109 Carbon Dioxide Increased 17 21.4 21.5 signal
110 Iron Deficiency 55 21.3 21.4 signal
111 Respiratory Acidosis 47 20.6 20.7 signal
112 Respiration Abnormal 77 19.4 19.5 signal
113 Blood Uric Acid Increased 64 19.1 19.2 signal
114 Activated Partial Thromboplastin Time Prolonged 56 18.9 19.0 signal
115 Appetite Disorder 71 18.7 18.8 signal
116 Intervertebral Disc Degeneration 101 18.7 18.8 signal
117 Left Ventricular Failure 37 18.6 18.7 signal
118 Calculus Urinary 16 17.9 17.9 signal
119 Respiratory Symptom 29 17.8 17.8 signal
120 Hypoventilation 34 17.8 17.8 signal
121 Productive Cough 459 16.6 17.3 signal
122 Postictal State 10 16.6 16.6 signal
123 Eosinophilic Granulomatosis With Polyangiitis 19 16.1 16.2 signal
124 Gout 169 16.1 16.4 signal
125 Sinus Tachycardia 133 16.1 16.3 signal
126 Conduction Disorder 17 16.0 16.0 signal
127 Respiratory Alkalosis 15 15.9 15.9 signal
128 Tonic Convulsion 13 15.9 15.9 signal
129 Chronic Respiratory Failure 11 15.9 15.9 signal
130 Painful Respiration 22 15.7 15.7 signal
131 Lobar Pneumonia 17 15.5 15.6 signal
132 Status Epilepticus 102 15.5 15.6 signal
133 Emphysema 90 15.3 15.4 signal
134 Hypophosphataemia 64 14.9 15.0 signal
135 Pulmonary Function Test Decreased 38 14.8 14.9 signal
136 Drug Level Above Therapeutic 39 14.7 14.8 signal
137 Ventricular Fibrillation 95 14.6 14.7 signal
138 Sleep Apnoea Syndrome 162 14.5 14.7 signal
139 Normocytic Anaemia 12 14.3 14.3 signal
140 Obesity 133 14.3 14.4 signal
141 Rhinitis 67 14.2 14.3 signal
142 Electrocardiogram St Segment Depression 18 14.0 14.0 signal
143 Tunnel Vision 15 13.8 13.8 signal
144 Tachyarrhythmia 20 13.7 13.7 signal
145 Paranasal Sinus Hypersecretion 30 13.4 13.4 signal
146 Increased Bronchial Secretion 20 13.4 13.4 signal
147 Appendicitis 72 13.3 13.3 signal
148 Encephalitis Autoimmune 10 13.3 13.3 signal
149 Latent Tuberculosis 16 13.1 13.1 signal
150 Blood Count Abnormal 117 13.0 13.2 signal
151 Sputum Increased 16 13.0 13.0 signal
152 Multiple Drug Overdose 38 12.9 13.0 signal
153 Myasthenia Gravis 59 12.8 12.9 signal
154 Lower Respiratory Tract Infection 336 12.7 13.0 signal
155 Flank Pain 67 12.3 12.3 signal
156 Dyspnoea Exertional 267 12.2 12.4 signal
157 Hypercholesterolaemia 68 12.2 12.2 signal
158 Supraventricular Extrasystoles 24 12.2 12.2 signal
159 Hyperaemia 14 12.1 12.1 signal
160 Glossitis 25 12.0 12.1 signal
161 Small Intestinal Perforation 13 11.8 11.9 signal
162 Pleuritic Pain 19 11.7 11.7 signal
163 Loss Of Personal Independence In Daily Activities 323 11.6 11.9 signal
164 Eosinophil Count Increased 56 11.5 11.6 signal
165 Drug Toxicity 92 11.4 11.5 signal
166 Aortic Arteriosclerosis 17 11.3 11.3 signal
167 Drug Level Increased 108 11.2 11.2 signal
168 Polymyalgia Rheumatica 20 11.0 11.0 signal
169 Affective Disorder 50 10.9 11.0 signal
170 Therapeutic Product Effect Incomplete 439 10.6 11.0 signal
171 Cushingoid 20 10.6 10.6 signal
172 Supraventricular Tachycardia 59 10.6 10.6 signal
173 Multiple Drug Overdose Intentional 20 10.5 10.5 signal
174 Eosinophilic Pneumonia 19 10.4 10.4 signal
175 Blood Calcium Increased 53 10.3 10.4 signal
176 Electrocardiogram St Segment Elevation 20 10.3 10.3 signal
177 Quadriparesis 10 10.3 10.3 signal
178 Troponin Increased 45 10.2 10.2 signal
179 Respiratory Rate Increased 53 10.2 10.2 signal
180 Ear Congestion 16 10.1 10.1 signal
181 Gastrointestinal Necrosis 17 10.0 10.0 signal
182 Capillary Leak Syndrome 12 10.0 10.0 signal
183 Hyperlipidaemia 70 10.0 10.0 signal
184 Glaucoma 112 9.9 10.0 signal
185 Therapeutic Agent Toxicity 19 9.6 9.6 signal
186 Ventricular Arrhythmia 20 9.4 9.4 signal
187 Asthmatic Crisis 20 9.3 9.4 signal
188 Pneumonia Klebsiella 10 9.3 9.3 signal
189 Respiratory Disorder 162 9.2 9.3 signal
190 Bladder Pain 17 9.2 9.2 signal
191 Pulmonary Congestion 71 9.2 9.2 signal
192 Bronchospasm 75 9.0 9.0 signal
193 Toxic Epidermal Necrolysis 79 9.0 9.0 signal
194 Seasonal Allergy 73 8.8 8.9 signal
195 Candidiasis 21 8.8 8.8 signal
196 Gastroenteritis 75 8.8 8.8 signal
197 Cardiogenic Shock 73 8.7 8.8 signal
198 Hyperventilation 29 8.5 8.6 signal
199 Wheelchair User 22 8.4 8.4 signal
200 Food Allergy 37 8.4 8.4 signal
201 Breast Disorder 10 8.4 8.4 signal
202 Acute Psychosis 12 8.3 8.3 signal
203 Diverticulum Intestinal Haemorrhagic 11 8.3 8.3 signal
204 Pseudomonas Infection 41 8.3 8.3 signal
205 Drug Hypersensitivity 940 8.3 8.9 signal
206 Nasal Polyps 23 8.1 8.2 signal
207 Cerebral Atrophy 19 8.1 8.1 signal
208 Atrial Tachycardia 10 8.1 8.1 signal
209 Rhinitis Allergic 21 8.1 8.1 signal
210 Aspiration 51 8.0 8.1 signal
211 Bacterial Infection 87 8.0 8.1 signal
212 Ventricular Hypokinesia 15 8.0 8.0 signal
213 Wound Complication 16 7.9 7.9 signal
214 Myopathy 40 7.9 7.9 signal
215 Blood Chloride Decreased 12 7.9 7.9 signal
216 Blood Lactic Acid Increased 24 7.8 7.8 signal
217 Blood Test Abnormal 64 7.8 7.8 signal
218 Pneumonia 1,468 7.8 8.7 signal
219 Paranasal Sinus Discomfort 17 7.7 7.7 signal
220 Dermatitis Allergic 56 7.7 7.7 signal
221 Acute Respiratory Failure 86 7.7 7.7 signal
222 Dyspnoea At Rest 13 7.7 7.7 signal
223 Gastrointestinal Hypomotility 10 7.7 7.7 signal
224 Nasal Congestion 254 7.4 7.5 signal
225 Ocular Discomfort 47 7.4 7.4 signal
226 Dyspnoea 2,440 7.4 8.9 signal
227 Osteoporosis 177 7.3 7.4 signal
228 Skin Abrasion 20 7.3 7.3 signal
229 Myocardial Ischaemia 48 7.1 7.2 signal
230 Skin Laceration 45 7.1 7.1 signal
231 Wound Secretion 16 6.9 7.0 signal
232 Eosinophilia 70 6.8 6.9 signal
233 Crepitations 12 6.8 6.8 signal
234 Cough 1,118 6.8 7.4 signal
235 Chest Discomfort 406 6.8 7.0 signal
236 Pulmonary Mass 59 6.8 6.8 signal
237 Erysipelas 20 6.8 6.8 signal
238 Blood Pressure Inadequately Controlled 24 6.8 6.8 signal
239 Arteriosclerosis Coronary Artery 26 6.7 6.7 signal
240 Ventricular Tachycardia 65 6.7 6.7 signal
241 Upper Respiratory Tract Infection 180 6.7 6.7 signal
242 Haemodialysis 33 6.6 6.6 signal
243 Synovial Cyst 18 6.6 6.6 signal
244 Increased Upper Airway Secretion 20 6.6 6.6 signal
245 Grand Mal Convulsion 36 6.6 6.6 signal
246 Pneumonia Bacterial 35 6.5 6.6 signal
247 Haemoptysis 107 6.5 6.6 signal
248 Stridor 11 6.4 6.4 signal
249 Sinus Disorder 74 6.4 6.4 signal
250 Labelled Drug-drug Interaction Medication Error 33 6.3 6.3 signal
251 Chest Pain 686 6.3 6.6 signal
252 Incorrect Route Of Product Administration 62 6.3 6.3 signal
253 Exercise Tolerance Decreased 21 6.3 6.3 signal
254 Ankle Fracture 57 6.3 6.3 signal
255 Lung Disorder 180 6.3 6.4 signal
256 Anorexia 48 6.3 6.3 signal
257 Hypokalaemia 168 6.2 6.3 signal
258 Ventricular Extrasystoles 38 6.2 6.3 signal
259 Ulcer 58 6.2 6.2 signal
260 Peptic Ulcer 12 6.2 6.2 signal
261 End Stage Renal Disease 66 6.1 6.1 signal
262 Ischaemic Cardiomyopathy 11 6.1 6.1 signal
263 Oral Candidiasis 46 6.0 6.1 signal
264 Atrial Fibrillation 337 5.9 6.0 signal
265 Respiratory Failure 252 5.9 6.0 signal
266 Pneumonia Viral 11 5.9 5.9 signal
267 Snoring 13 5.9 5.9 signal
268 Electrocardiogram Abnormal 27 5.8 5.9 signal
269 Extrasystoles 24 5.8 5.8 signal
270 Cardiomegaly 42 5.8 5.8 signal
271 Blood Pressure Diastolic Decreased 25 5.8 5.8 signal
272 Hypoxia 118 5.7 5.8 signal
273 Cyanosis 53 5.7 5.8 signal
274 Angina Pectoris 97 5.7 5.8 signal
275 Mitral Valve Incompetence 38 5.7 5.7 signal
276 Ascites 98 5.7 5.7 signal
277 Rib Fracture 68 5.7 5.7 signal
278 Blood Iron Decreased 39 5.6 5.7 signal
279 Hearing Impaired 20 5.6 5.6 signal
280 Lung Infiltration 29 5.6 5.6 signal
281 Azotaemia 13 5.5 5.5 signal
282 Hiatus Hernia 42 5.5 5.5 signal
283 Gastrooesophageal Reflux Disease 259 5.5 5.6 signal
284 Atrioventricular Block First Degree 14 5.5 5.5 signal
285 Sudden Cardiac Death 11 5.5 5.5 signal
286 Respiratory Tract Congestion 51 5.5 5.5 signal
287 Depression Suicidal 11 5.4 5.4 signal
288 Cardiomyopathy 47 5.4 5.4 signal
289 Coronary Artery Stenosis 16 5.4 5.4 signal
290 Rhinovirus Infection 12 5.4 5.4 signal
291 Cardiac Failure Congestive 255 5.4 5.5 signal
292 Acidosis 24 5.3 5.4 signal
293 Carotid Artery Stenosis 11 5.3 5.3 signal
294 Orthopnoea 10 5.3 5.3 signal
295 Cardiac Murmur 27 5.3 5.3 signal
296 Oxygen Saturation Decreased 173 5.3 5.3 signal
297 Congestive Cardiomyopathy 13 5.2 5.2 signal
298 Stevens-johnson Syndrome 68 5.2 5.2 signal
299 Bundle Branch Block Right 14 5.2 5.2 signal
300 Oedema Mouth 10 5.2 5.2 signal
301 Knee Arthroplasty 63 5.2 5.2 signal
302 Body Temperature Decreased 30 5.2 5.2 signal
303 Abdominal Tenderness 15 5.1 5.2 signal
304 Pleurisy 18 5.1 5.2 signal
305 Bronchitis 224 5.1 5.2 signal
306 Hypoacusis 128 5.1 5.1 signal
307 Depressed Mood 155 5.0 5.1 signal
308 Hyperuricaemia 12 5.0 5.0 signal
309 Tricuspid Valve Incompetence 23 5.0 5.0 signal
310 Refusal Of Treatment By Patient 19 5.0 5.0 signal
311 Angina Unstable 19 4.9 4.9 signal
312 Circulatory Collapse 49 4.9 4.9 signal
313 Weight Loss Poor 13 4.9 4.9 signal
314 Rhinorrhoea 183 4.8 4.9 signal
315 Multiple Organ Dysfunction Syndrome 79 4.8 4.9 signal
316 Aortic Valve Incompetence 12 4.8 4.8 signal
317 Bundle Branch Block Left 12 4.8 4.8 signal
318 Multiple Allergies 22 4.8 4.8 signal
319 Left Ventricular Hypertrophy 12 4.8 4.8 signal
320 Lung Infection 44 4.8 4.8 signal
321 Pyelonephritis 24 4.8 4.8 signal
322 Oesophageal Candidiasis 11 4.7 4.7 signal
323 Pharmaceutical Product Complaint 73 4.7 4.7 signal
324 Apparent Death 10 4.7 4.7 signal
325 Tachycardia 241 4.6 4.7 signal
326 Ileus Paralytic 12 4.6 4.6 signal
327 Oropharyngeal Discomfort 24 4.6 4.6 signal
328 Leukocytosis 48 4.5 4.5 signal
329 Generalised Tonic-clonic Seizure 43 4.5 4.5 signal
330 Vomiting 1,231 4.5 4.9 signal
331 Aspergillus Infection 17 4.5 4.5 signal
332 Diabetic Neuropathy 13 4.5 4.5 signal
333 Generalised Oedema 32 4.4 4.4 signal
334 Coronary Artery Bypass 15 4.4 4.4 signal
335 Visual Disturbance 15 4.4 4.4 signal
336 Asphyxia 21 4.4 4.4 signal
337 Nephrogenic Anaemia 12 4.4 4.4 signal
338 Lung Neoplasm 11 4.4 4.4 signal
339 Clostridium Difficile Colitis 27 4.3 4.3 signal
340 Drug Interaction 402 4.3 4.4 signal
341 Neuralgia 61 4.3 4.3 signal
342 Spinal Column Stenosis 12 4.3 4.3 signal
343 Atrial Flutter 20 4.3 4.3 signal
344 Diabetes Mellitus 191 4.3 4.3 signal
345 Blood Pressure Systolic Increased 48 4.2 4.2 signal
346 Tooth Abscess 25 4.2 4.2 signal
347 Cataract 145 4.2 4.2 signal
348 Body Temperature Increased 50 4.2 4.2 signal
349 Hypertonia 14 4.1 4.2 signal
350 Middle Insomnia 45 4.1 4.1 signal
351 Convulsion 139 4.1 4.1 signal
352 Transient Ischaemic Attack 81 4.1 4.1 signal
353 Spinal Osteoarthritis 21 4.1 4.1 signal
354 Renal Failure Acute 102 4.0 4.1 signal
355 Inappropriate Antidiuretic Hormone Secretion 24 4.0 4.0 signal
356 Hyponatraemia 131 4.0 4.0 signal
357 Rhabdomyolysis 97 4.0 4.0 signal
358 Blood Potassium Decreased 70 4.0 4.0 signal
359 Sarcoidosis 11 3.9 3.9 signal
360 Ejection Fraction Decreased 36 3.9 3.9 signal
361 Renal Failure Chronic 18 3.9 3.9 signal
362 Stress 166 3.9 4.0 signal
363 Sleep Disorder 161 3.9 4.0 signal
364 Coronary Artery Disease 70 3.9 3.9 signal
365 Toxicity To Various Agents 383 3.9 4.0 signal
366 Pneumothorax 36 3.9 3.9 signal
367 Ear Pain 44 3.9 3.9 signal
368 Catheterisation Cardiac 10 3.8 3.8 signal
369 Blood Creatine Increased 10 3.8 3.8 signal
370 Sinusitis 230 3.8 3.9 signal
371 Neutropenic Sepsis 16 3.8 3.8 signal
372 Hypomagnesaemia 31 3.8 3.8 signal
373 Micturition Urgency 25 3.8 3.8 signal
374 Autoimmune Disorder 21 3.7 3.7 signal
375 Blood Cholesterol Increased 102 3.7 3.7 signal
376 Hypogammaglobulinaemia 14 3.7 3.7 signal
377 Adrenal Insufficiency 26 3.7 3.7 signal
378 Atelectasis 21 3.7 3.7 signal
379 Intentional Product Misuse 187 3.7 3.7 signal
380 Pulmonary Hypertension 45 3.7 3.7 signal
381 Prothrombin Time Prolonged 13 3.7 3.7 signal
382 Economic Problem 33 3.6 3.7 signal
383 Tachypnoea 29 3.6 3.7 signal
384 Poisoning 27 3.6 3.7 signal
385 Blood Urea Increased 36 3.6 3.7 signal
386 Partial Seizures 11 3.6 3.6 signal
387 Cerebral Ischaemia 11 3.6 3.6 signal
388 Neutrophilia 12 3.6 3.6 signal
389 Compression Fracture 11 3.6 3.6 signal
390 Multi-organ Failure 37 3.6 3.6 signal
391 Enterocolitis 12 3.6 3.6 signal
392 Pharyngitis 26 3.6 3.6 signal
393 Peritonitis Bacterial 21 3.6 3.6 signal
394 Herpes Zoster 120 3.6 3.6 signal
395 Escherichia Infection 17 3.5 3.5 signal
396 Depressed Level Of Consciousness 82 3.5 3.6 signal
397 Metabolic Disorder 12 3.5 3.5 signal
398 Hyperglycaemia 75 3.5 3.5 signal
399 Disseminated Intravascular Coagulation 29 3.5 3.5 signal
400 Metabolic Acidosis 65 3.5 3.5 signal
401 Hypovolaemia 12 3.5 3.5 signal
402 Arrhythmia 97 3.5 3.5 signal
403 Multiple Injuries 13 3.5 3.5 signal
404 Diabetes Mellitus Inadequate Control 36 3.5 3.5 signal
405 Hypercalcaemia 25 3.5 3.5 signal
406 Autoimmune Hepatitis 14 3.4 3.4 signal
407 Arteriosclerosis 19 3.4 3.4 signal
408 Type 2 Diabetes Mellitus 68 3.4 3.4 signal
409 Choking Sensation 11 3.4 3.4 signal
410 Acute Myocardial Infarction 59 3.4 3.4 signal
411 Sensory Disturbance 32 3.4 3.4 signal
412 Eye Pruritus 65 3.4 3.4 signal
413 Haematemesis 50 3.4 3.4 signal
414 Joint Injury 42 3.3 3.4 signal
415 Infusion Site Swelling 12 3.3 3.3 signal
416 Blood Creatine Phosphokinase Increased 57 3.3 3.3 signal
417 Femoral Neck Fracture 10 3.3 3.3 signal
418 Varicose Vein 10 3.3 3.3 signal
419 Apnoea 15 3.3 3.3 signal
420 Spinal Compression Fracture 16 3.2 3.2 signal
421 Dry Mouth 154 3.2 3.3 signal
422 Brain Oedema 24 3.2 3.2 signal
423 Heart Rate Increased 188 3.2 3.3 signal
424 Hypertension 400 3.2 3.3 signal
425 Respiratory Distress 52 3.2 3.2 signal
426 Encephalopathy 46 3.2 3.2 signal
427 Malaise 825 3.2 3.4 signal
428 Pharyngolaryngeal Pain 10 3.2 3.2 signal
429 Hypothyroidism 59 3.2 3.2 signal
430 Post Procedural Infection 15 3.2 3.2 signal
431 Ataxia 22 3.1 3.1 signal
432 Injury 130 3.1 3.2 signal
433 Upper-airway Cough Syndrome 15 3.1 3.1 signal
434 Intestinal Ischaemia 10 3.1 3.1 signal
435 Cardiac Failure 146 3.1 3.1 signal
436 Cardiac Failure Acute 12 3.1 3.1 signal
437 Dysphonia 105 3.1 3.1 signal
438 Skin Infection 20 3.1 3.1 signal
439 Pulmonary Haemorrhage 14 3.0 3.1 signal
440 Hypokinesia 26 3.0 3.1 signal
441 Pulmonary Alveolar Haemorrhage 10 3.0 3.0 signal
442 Torsade De Pointes 14 3.0 3.0 signal
443 Viral Infection 59 3.0 3.0 signal
444 Medication Error 98 3.0 3.0 signal
445 Wrist Fracture 21 3.0 3.0 signal
446 Drug Abuse 146 3.0 3.0 signal
447 Influenza 195 3.0 3.0 signal
448 Oedema Peripheral 213 3.0 3.0 signal
449 Pulmonary Oedema 78 3.0 3.0 signal
450 Respiratory Syncytial Virus Infection 15 3.0 3.0 signal
451 Mental Impairment 42 2.9 3.0 signal
452 Stress Cardiomyopathy 10 2.9 2.9 signal
453 Mental Status Changes 48 2.9 2.9 signal
454 Low Density Lipoprotein Increased 13 2.9 2.9 signal
455 White Blood Cell Count Increased 65 2.9 2.9 signal
456 Blood Creatinine Increased 110 2.9 2.9 signal
457 Motor Dysfunction 17 2.9 2.9 signal
458 Pharyngeal Swelling 16 2.8 2.8 signal
459 International Normalised Ratio Increased 48 2.8 2.8 signal
460 Blood Pressure Abnormal 33 2.8 2.8 signal
461 Disorientation 66 2.8 2.8 signal
462 Sinus Bradycardia 16 2.8 2.8 signal
463 Aphonia 23 2.8 2.8 signal
464 Arterial Occlusive Disease 13 2.8 2.8 signal
465 Liver Function Test Increased 35 2.8 2.8 signal
466 Acute Respiratory Distress Syndrome 29 2.8 2.8 signal
467 Restlessness 60 2.8 2.8 signal
468 Renal Cyst 13 2.8 2.8 signal
469 Hypoglycaemia 79 2.8 2.8 signal
470 Cellulitis 82 2.8 2.8 signal
471 Pulmonary Fibrosis 31 2.8 2.8 signal
472 Blood Magnesium Decreased 14 2.8 2.8 signal
473 Shock 37 2.8 2.8 signal
474 Hepatomegaly 16 2.8 2.8 signal
475 Concomitant Disease Aggravated 10 2.8 2.8 signal
476 Anuria 14 2.8 2.8 signal
477 Abdominal Distension 167 2.7 2.8 signal
478 Eye Movement Disorder 11 2.7 2.7 signal
479 Choking 31 2.7 2.7 signal
480 Delirium 55 2.7 2.7 signal
481 Dermatitis Contact 18 2.7 2.7 signal
482 Respiratory Arrest 44 2.7 2.7 signal
483 Hallucination, Visual 33 2.7 2.7 signal
484 Body Height Decreased 17 2.7 2.7 signal
485 Nocturia 19 2.7 2.7 signal
486 C-reactive Protein Increased 57 2.7 2.7 signal
487 Ocular Hyperaemia 73 2.7 2.7 signal
488 Acute Coronary Syndrome 13 2.7 2.7 signal
489 Unresponsive To Stimuli 40 2.6 2.7 signal
490 Musculoskeletal Chest Pain 24 2.6 2.6 signal
491 Drug Intolerance 149 2.6 2.7 signal
492 Atrioventricular Block 12 2.6 2.6 signal
493 Condition Aggravated 467 2.6 2.7 signal
494 Arthropathy 86 2.6 2.6 signal
495 Dysarthria 58 2.6 2.6 signal
496 Blood Pressure Fluctuation 37 2.6 2.6 signal
497 Rectal Haemorrhage 66 2.6 2.6 signal
498 Diverticulum 11 2.6 2.6 signal
499 Pneumonia Aspiration 38 2.6 2.6 signal
500 Sepsis 170 2.6 2.6 signal
501 Dysuria 56 2.6 2.6 signal
502 Tremor 252 2.6 2.6 signal
503 General Physical Health Deterioration 174 2.6 2.6 signal
504 Major Depression 11 2.6 2.6 signal
505 Left Ventricular Dysfunction 10 2.6 2.6 signal
506 Atrioventricular Block Complete 10 2.5 2.6 signal
507 Sudden Death 16 2.5 2.5 signal
508 Heart Rate Irregular 34 2.5 2.6 signal
509 Intentional Overdose 95 2.5 2.5 signal
510 Blood Sodium Decreased 28 2.5 2.5 signal
511 Aspartate Aminotransferase Increased 79 2.5 2.5 signal
512 Dry Throat 15 2.5 2.5 signal
513 Sneezing 33 2.5 2.5 signal
514 Decubitus Ulcer 12 2.5 2.5 signal
515 Hyperthermia 11 2.5 2.5 signal
516 Drug Exposure During Pregnancy 50 2.5 2.5 signal
517 Cardiovascular Disorder 37 2.5 2.5 signal
518 Candida Infection 24 2.4 2.5 signal
519 Hemiplegia 12 2.4 2.4 signal
520 Feeling Cold 40 2.4 2.4 signal
521 Haematuria 49 2.4 2.4 signal
522 Urinary Incontinence 42 2.4 2.4 signal
523 Depression 324 2.4 2.5 signal
524 Right Ventricular Failure 10 2.4 2.4 signal
525 Suicide Attempt 86 2.4 2.4 signal
526 Pleural Effusion 86 2.4 2.4 signal
527 Blood Pressure Increased 216 2.4 2.4 signal
528 Nervous System Disorder 44 2.4 2.4 signal
529 Hernia 27 2.4 2.4 signal
530 Fluid Retention 71 2.4 2.4 signal
531 Drug Screen Positive 11 2.4 2.4 signal
532 Electrolyte Imbalance 16 2.4 2.4 signal
533 Muscle Strain 12 2.4 2.4 signal
534 Respiratory Depression 17 2.4 2.4 signal
535 Laryngitis 15 2.4 2.4 signal
536 Ileus 17 2.4 2.4 signal
537 Coronary Artery Occlusion 19 2.3 2.3 signal
538 Hypocalcaemia 26 2.3 2.3 signal
539 Dyspepsia 135 2.3 2.4 signal
540 Tongue Disorder 10 2.3 2.3 signal
541 Interstitial Lung Disease 66 2.3 2.3 signal
542 Anaphylactic Shock 35 2.3 2.3 signal
543 Dysstasia 40 2.3 2.3 signal
544 Weight Increased 304 2.3 2.4 signal
545 Blood Urine Present 26 2.3 2.3 signal
546 Conjunctivitis 25 2.3 2.3 signal
547 Caesarean Section 16 2.3 2.3 signal
548 Mass 19 2.3 2.3 signal
549 Cardio-respiratory Arrest 57 2.3 2.3 signal
550 Polyuria 11 2.3 2.3 signal
551 Dysphagia 127 2.3 2.3 signal
552 Palpitations 156 2.3 2.3 signal
553 Haemorrhage Intracranial 20 2.3 2.3 signal
554 Hypoaesthesia Oral 20 2.3 2.3 signal
555 Rebound Effect 15 2.3 2.3 signal
556 Localised Infection 32 2.3 2.3 signal
557 Cardiac Arrest 109 2.2 2.3 signal
558 Weight Decreased 367 2.2 2.3 signal
559 Gastric Ulcer 25 2.2 2.2 signal
560 Osteopenia 20 2.2 2.2 signal
561 Nasopharyngitis 242 2.2 2.3 signal
562 Haematocrit Decreased 26 2.2 2.2 signal
563 Pyrexia 450 2.2 2.3 signal
564 Altered State Of Consciousness 28 2.2 2.2 signal
565 Throat Irritation 58 2.2 2.2 signal
566 Secretion Discharge 16 2.2 2.2 signal
567 Tendon Rupture 16 2.2 2.2 signal
568 Limb Injury 35 2.2 2.2 signal
569 Hemiparesis 22 2.2 2.2 signal
570 Completed Suicide 108 2.2 2.2 signal
571 Anxiety 365 2.2 2.2 signal
572 Nephropathy 12 2.2 2.2 signal
573 Coagulopathy 21 2.2 2.2 signal
574 Neuroleptic Malignant Syndrome 15 2.1 2.1 signal
575 Polyneuropathy 15 2.1 2.1 signal
576 Low Birth Weight Baby 10 2.1 2.1 signal
577 Gingival Pain 10 2.1 2.1 signal
578 Blood Lactate Dehydrogenase Increased 20 2.1 2.1 signal
579 Eczema 63 2.1 2.1 signal
580 Thrombosis 101 2.1 2.1 signal
581 Impaired Quality Of Life 18 2.1 2.1 signal
582 Pulmonary Embolism 119 2.1 2.1 signal
583 Pain 765 2.1 2.2 signal
584 Rotator Cuff Syndrome 16 2.1 2.1 signal
585 Hepatic Function Abnormal 46 2.1 2.1 signal
586 Hypotension 248 2.1 2.1 signal
587 Oropharyngeal Pain 114 2.1 2.1 signal
588 Muscle Disorder 10 2.1 2.1 signal
589 Incontinence 13 2.1 2.1 signal
590 Laboratory Test Abnormal 36 2.1 2.1 signal
591 Renal Tubular Necrosis 12 2.1 2.1 signal
592 Anaphylactic Reaction 67 2.1 2.1 signal
593 Pharyngeal Oedema 19 2.1 2.1 signal
594 Gastritis 32 2.1 2.1 signal
595 Ligament Sprain 12 2.1 2.1 signal
596 Gait Inability 40 2.1 2.1 signal
597 Hyperkalaemia 42 2.0 2.1 signal
598 Bone Disorder 22 2.0 2.0 signal
599 Liver Disorder 53 2.0 2.0 signal
600 Mental Disorder 52 2.0 2.0 signal
601 Device Failure 18 2.0 2.0 signal
602 Upper Gastrointestinal Haemorrhage 20 2.0 2.0 signal
603 Dehydration 158 2.0 2.0 signal
604 Dermatitis Atopic 59 2.0 2.0 signal
605 Nephrolithiasis 54 2.0 2.0 signal
606 Dental Caries 13 2.0 2.0 signal
607 Accident 14 2.0 2.0 signal
608 Drug Level Decreased 12 2.0 2.0 no signal
609 Blood Potassium Increased 19 2.0 2.0 no signal
610 Swelling 109 2.0 2.0 no signal
611 Squamous Cell Carcinoma 11 2.0 2.0 no signal
612 Pulmonary Arterial Hypertension 17 2.0 2.0 no signal
613 Haemoglobin Decreased 120 2.0 2.0 no signal
614 Spinal Disorder 11 2.0 2.0 no signal
615 Renal Failure 155 2.0 2.0 no signal
616 Arthritis 91 2.0 2.0 no signal
617 Somnolence 232 2.0 2.0 no signal
618 Overdose 248 1.9 2.0 no signal
619 Anaemia 218 1.9 2.0 no signal
620 Intervertebral Disc Protrusion 25 1.9 1.9 no signal
621 Melaena 25 1.9 1.9 no signal
622 No Therapeutic Response 14 1.9 1.9 no signal
623 Blood Pressure Decreased 75 1.9 1.9 no signal
624 Hepatic Steatosis 21 1.9 1.9 no signal
625 Transaminases Increased 25 1.9 1.9 no signal
626 Gastrointestinal Haemorrhage 94 1.9 1.9 no signal
627 Adverse Drug Reaction 100 1.9 1.9 no signal
628 Haematoma 29 1.9 1.9 no signal
629 Myocardial Infarction 196 1.9 1.9 no signal
630 Dementia 31 1.9 1.9 no signal
631 Splenomegaly 13 1.9 1.9 no signal
632 Sinus Congestion 15 1.9 1.9 no signal
633 Faeces Discoloured 24 1.9 1.9 no signal
634 Bacteraemia 13 1.9 1.9 no signal
635 Thyroid Disorder 17 1.9 1.9 no signal
636 Syncope 110 1.9 1.9 no signal
637 Infusion Site Pain 14 1.9 1.9 no signal
638 Activities Of Daily Living Impaired 22 1.9 1.9 no signal
639 Abdominal Pain 254 1.9 1.9 no signal
640 Bradycardia 58 1.9 1.9 no signal
641 Blood Glucose Fluctuation 12 1.9 1.9 no signal
642 Iron Deficiency Anaemia 10 1.9 1.9 no signal
643 Diverticulitis 30 1.8 1.8 no signal
644 Muscular Weakness 123 1.8 1.9 no signal
645 Abasia 27 1.8 1.8 no signal
646 Jaundice 29 1.8 1.8 no signal
647 Throat Tightness 29 1.8 1.8 no signal
648 Musculoskeletal Stiffness 94 1.8 1.8 no signal
649 Panic Attack 39 1.8 1.8 no signal
650 Infection 154 1.8 1.8 no signal
651 Fall 355 1.8 1.8 no signal
652 Intentional Dose Omission 29 1.8 1.8 no signal
653 Pain In Extremity 312 1.8 1.8 no signal
654 Discomfort 64 1.8 1.8 no signal
655 Product Administration Error 21 1.8 1.8 no signal
656 Procedural Pain 29 1.8 1.8 no signal
657 Joint Dislocation 11 1.8 1.8 no signal
658 Dizziness Postural 10 1.8 1.8 no signal
659 Epistaxis 78 1.8 1.8 no signal
660 Product Quality Issue 140 1.8 1.8 no signal
661 Drug-induced Liver Injury 32 1.8 1.8 no signal
662 Seizure 119 1.8 1.8 no signal
663 Gamma-glutamyltransferase Increased 23 1.8 1.8 no signal
664 Osteoarthritis 44 1.8 1.8 no signal
665 Blister 58 1.8 1.8 no signal
666 Delusion 16 1.8 1.8 no signal
667 Orthostatic Hypotension 18 1.8 1.8 no signal
668 Tendonitis 16 1.8 1.8 no signal
669 Premature Baby 31 1.7 1.7 no signal
670 Decreased Activity 11 1.7 1.7 no signal
671 Vitamin D Deficiency 10 1.7 1.7 no signal
672 Liver Function Test Abnormal 30 1.7 1.7 no signal
673 Urinary Retention 34 1.7 1.7 no signal
674 Impaired Gastric Emptying 13 1.7 1.7 no signal
675 Contusion 98 1.7 1.7 no signal
676 Local Swelling 18 1.7 1.7 no signal
677 Epilepsy 31 1.7 1.7 no signal
678 Dizziness 503 1.7 1.8 no signal
679 Cholecystitis 12 1.7 1.7 no signal
680 Pollakiuria 42 1.7 1.7 no signal
681 Bladder Disorder 10 1.7 1.7 no signal
682 Blood Alkaline Phosphatase Increased 25 1.7 1.7 no signal
683 Agitation 74 1.7 1.7 no signal
684 Colon Cancer 15 1.7 1.7 no signal
685 Foot Fracture 19 1.7 1.7 no signal
686 Pneumonitis 27 1.7 1.7 no signal
687 Skin Reaction 14 1.7 1.7 no signal
688 Amnesia 65 1.7 1.7 no signal
689 Treatment Noncompliance 54 1.7 1.7 no signal
690 Swollen Tongue 31 1.7 1.7 no signal
691 Insomnia 263 1.7 1.7 no signal
692 Head Injury 31 1.7 1.7 no signal
693 Cerebral Infarction 24 1.7 1.7 no signal
694 Hypersensitivity 181 1.7 1.7 no signal
695 Urosepsis 9 1.7 1.7 no signal
696 Neutrophil Count Increased 10 1.7 1.7 no signal
697 Haemorrhoids 19 1.7 1.7 no signal
698 Confusional State 157 1.7 1.7 no signal
699 Constipation 208 1.6 1.6 no signal
700 Asthenia 361 1.6 1.7 no signal
701 Tenderness 10 1.6 1.6 no signal
702 Pruritus Generalised 21 1.6 1.6 no signal
703 Pericardial Effusion 22 1.6 1.6 no signal
704 Spinal Fracture 19 1.6 1.6 no signal
705 Hyperhidrosis 122 1.6 1.6 no signal
706 Chills 111 1.6 1.6 no signal
707 Coma 45 1.6 1.6 no signal
708 Back Pain 219 1.6 1.6 no signal
709 Pancreatitis Acute 21 1.6 1.6 no signal
710 Chronic Kidney Disease 72 1.6 1.6 no signal
711 Gastroenteritis Viral 17 1.6 1.6 no signal
712 Hypoaesthesia 139 1.6 1.6 no signal
713 Oesophagitis 10 1.6 1.6 no signal
714 Loss Of Consciousness 117 1.6 1.6 no signal
715 Immune System Disorder 12 1.6 1.6 no signal
716 Unevaluable Event 69 1.6 1.6 no signal
717 Lethargy 52 1.5 1.5 no signal
718 Hip Fracture 29 1.5 1.5 no signal
719 Pneumocystis Jirovecii Pneumonia 9 1.5 1.5 no signal
720 Hypotonia 9 1.5 1.5 no signal
721 Lung Neoplasm Malignant 37 1.5 1.5 no signal
722 Ovarian Cyst 9 1.5 1.5 no signal
723 Product Taste Abnormal 12 1.5 1.5 no signal
724 Musculoskeletal Pain 47 1.5 1.5 no signal
725 Synovitis 16 1.5 1.5 no signal
726 Cardiac Disorder 83 1.5 1.5 no signal
727 Urinary Tract Infection 150 1.5 1.5 no signal
728 Therapeutic Response Decreased 53 1.5 1.5 no signal
729 Renal Disorder 41 1.5 1.5 no signal
730 Cystitis 28 1.5 1.5 no signal
731 Staphylococcal Infection 29 1.5 1.5 no signal
732 Nervousness 46 1.5 1.5 no signal
733 Abdominal Discomfort 146 1.5 1.5 no signal
734 Dystonia 17 1.5 1.5 no signal
735 Peripheral Swelling 134 1.5 1.5 no signal
736 Maternal Exposure During Pregnancy 77 1.5 1.5 no signal
737 Renal Impairment 73 1.5 1.5 no signal
738 Gait Disturbance 167 1.5 1.5 no signal
739 Scratch 9 1.5 1.5 no signal
740 Anhedonia 23 1.5 1.5 no signal
741 Muscle Spasms 159 1.5 1.5 no signal
742 Weight Fluctuation 9 1.5 1.5 no signal
743 Swelling Face 56 1.5 1.5 no signal
744 Disability 17 1.5 1.5 no signal
745 Back Disorder 14 1.5 1.5 no signal
746 Carpal Tunnel Syndrome 12 1.5 1.5 no signal
747 Myalgia 145 1.5 1.5 no signal
748 Renal Pain 9 1.4 1.4 no signal
749 Drug Eruption 15 1.4 1.4 no signal
750 Cold Sweat 15 1.4 1.4 no signal
751 Nausea 668 1.4 1.5 no signal
752 Breast Pain 9 1.4 1.4 no signal
753 Dialysis 12 1.4 1.4 no signal
754 Covid-19 Pneumonia 10 1.4 1.4 no signal
755 Neck Pain 47 1.4 1.4 no signal
756 Laceration 8 1.4 1.4 no signal
757 Red Blood Cell Count Decreased 24 1.4 1.4 no signal
758 Toothache 15 1.4 1.4 no signal
759 Bursitis 10 1.4 1.4 no signal
760 Presyncope 20 1.4 1.4 no signal
761 Decreased Appetite 189 1.4 1.4 no signal
762 Kidney Infection 16 1.4 1.4 no signal
763 Small Intestinal Obstruction 10 1.4 1.4 no signal
764 Neutrophil Count Decreased 33 1.4 1.4 no signal
765 Neuropathy Peripheral 77 1.4 1.4 no signal
766 Hallucination 61 1.4 1.4 no signal
767 Fluid Overload 12 1.4 1.4 no signal
768 Malnutrition 9 1.4 1.4 no signal
769 Insurance Issue 12 1.4 1.4 no signal
770 Electrocardiogram Qt Prolonged 29 1.4 1.4 no signal
771 Gingival Bleeding 11 1.4 1.4 no signal
772 Dysgeusia 60 1.4 1.4 no signal
773 Oral Pain 18 1.4 1.4 no signal
774 Tubulointerstitial Nephritis 15 1.4 1.4 no signal
775 Alanine Aminotransferase Increased 49 1.4 1.4 no signal
776 Cholecystectomy 9 1.3 1.3 no signal
777 Abnormal Dreams 22 1.3 1.3 no signal
778 Impaired Driving Ability 9 1.3 1.3 no signal
779 Suicidal Ideation 72 1.3 1.3 no signal
780 Feeling Hot 48 1.3 1.3 no signal
781 Psychomotor Hyperactivity 13 1.3 1.3 no signal
782 Post Procedural Complication 15 1.3 1.3 no signal
783 Lactic Acidosis 25 1.3 1.3 no signal
784 Aggression 39 1.3 1.3 no signal
785 Tuberculosis 10 1.3 1.3 no signal
786 Movement Disorder 25 1.3 1.3 no signal
787 Lymphoma 12 1.3 1.3 no signal
788 Femur Fracture 24 1.3 1.3 no signal
789 Vasculitis 9 1.3 1.3 no signal
790 Petechiae 8 1.3 1.3 no signal
791 Cholelithiasis 25 1.3 1.3 no signal
792 Acute Kidney Injury 116 1.3 1.3 no signal
793 Brain Neoplasm 7 1.3 1.3 no signal
794 Retinal Detachment 7 1.3 1.3 no signal
795 Mouth Ulceration 16 1.3 1.3 no signal
796 Aphasia 23 1.3 1.3 no signal
797 Macular Degeneration 9 1.3 1.3 no signal
798 Myoclonus 9 1.3 1.3 no signal
799 Paraesthesia 119 1.3 1.3 no signal
800 Hallucination, Auditory 12 1.3 1.3 no signal
801 Arthralgia 312 1.3 1.3 no signal
802 Cerebrovascular Accident 128 1.3 1.3 no signal
803 Prescribed Underdose 15 1.3 1.3 no signal
804 Balance Disorder 65 1.3 1.3 no signal
805 Hepatic Encephalopathy 7 1.3 1.3 no signal
806 Adverse Event 69 1.3 1.3 no signal
807 Diarrhoea Haemorrhagic 7 1.3 1.3 no signal
808 Vision Blurred 102 1.3 1.3 no signal
809 Hunger 10 1.3 1.3 no signal
810 Pain In Jaw 21 1.3 1.3 no signal
811 Wound Infection 8 1.3 1.3 no signal
812 Disease Recurrence 35 1.2 1.2 no signal
813 Metastases To Bone 12 1.2 1.2 no signal
814 Lower Limb Fracture 14 1.2 1.2 no signal
815 Thirst 13 1.2 1.2 no signal
816 Mucosal Inflammation 19 1.2 1.2 no signal
817 Therapeutic Response Shortened 23 1.2 1.2 no signal
818 Deep Vein Thrombosis 47 1.2 1.2 no signal
819 Osteomyelitis 13 1.2 1.2 no signal
820 Restless Legs Syndrome 13 1.2 1.2 no signal
821 Accidental Overdose 26 1.2 1.2 no signal
822 Blood Calcium Decreased 8 1.2 1.2 no signal
823 Angioedema 31 1.2 1.2 no signal
824 Mydriasis 9 1.2 1.2 no signal
825 Influenza Like Illness 58 1.2 1.2 no signal
826 Salivary Hypersecretion 7 1.2 1.2 no signal
827 Renal Injury 21 1.2 1.2 no signal
828 Joint Swelling 84 1.2 1.2 no signal
829 Hepatic Failure 21 1.2 1.2 no signal
830 Septic Shock 30 1.2 1.2 no signal
831 Hyperthyroidism 10 1.2 1.2 no signal
832 Gastric Haemorrhage 8 1.2 1.2 no signal
833 Nodule 9 1.2 1.2 no signal
834 Deafness 18 1.2 1.2 no signal
835 Rash Generalised 18 1.2 1.2 no signal
836 Eyelid Oedema 8 1.2 1.2 no signal
837 Cytokine Release Syndrome 13 1.2 1.2 no signal
838 Feeling Jittery 13 1.2 1.2 no signal
839 Limb Discomfort 21 1.2 1.2 no signal
840 Psychotic Disorder 20 1.2 1.2 no signal
841 Dermatitis 14 1.1 1.1 no signal
842 Joint Range Of Motion Decreased 9 1.1 1.1 no signal
843 Product Dose Omission Issue 191 1.1 1.1 no signal
844 Burning Sensation 47 1.1 1.1 no signal
845 Haemorrhage 70 1.1 1.1 no signal
846 Speech Disorder 35 1.1 1.1 no signal
847 Urticaria 111 1.1 1.1 no signal
848 Therapy Cessation 34 1.1 1.1 no signal
849 Blood Glucose Decreased 32 1.1 1.1 no signal
850 Contraindicated Product Administered 20 1.1 1.1 no signal
851 Pancreatitis 35 1.1 1.1 no signal
852 Fungal Infection 22 1.1 1.1 no signal
853 Gastric Disorder 23 1.1 1.1 no signal
854 Fibromyalgia 16 1.1 1.1 no signal
855 Hip Arthroplasty 10 1.1 1.1 no signal
856 Skin Ulcer 17 1.1 1.1 no signal
857 Heart Rate Decreased 23 1.1 1.1 no signal
858 Increased Tendency To Bruise 6 1.1 1.1 no signal
859 Blood Glucose Increased 123 1.1 1.1 no signal
860 Fatigue 505 1.1 1.1 no signal
861 Back Injury 7 1.1 1.1 no signal
862 Road Traffic Accident 27 1.1 1.1 no signal
863 Cognitive Disorder 30 1.1 1.1 no signal
864 Headache 403 1.1 1.1 no signal
865 Osteonecrosis Of Jaw 16 1.1 1.1 no signal
866 Intestinal Obstruction 24 1.1 1.1 no signal
867 Drug Effect Decreased 35 1.1 1.1 no signal
868 Deformity 6 1.1 1.1 no signal
869 Increased Appetite 12 1.1 1.1 no signal
870 Eye Inflammation 6 1.1 1.1 no signal
871 Tooth Fracture 7 1.1 1.1 no signal
872 Eye Pain 35 1.1 1.1 no signal
873 Neurotoxicity 11 1.1 1.1 no signal
874 Bone Pain 37 1.1 1.1 no signal
875 Hypophagia 16 1.1 1.1 no signal
876 Hypersomnia 18 1.1 1.1 no signal
877 Therapy Non-responder 28 1.1 1.1 no signal
878 Metastases To Liver 11 1.1 1.1 no signal
879 Visual Acuity Reduced 21 1.1 1.1 no signal
880 Hypertensive Crisis 7 1.1 1.1 no signal
881 Subdural Haematoma 9 1.1 1.1 no signal
882 Ill-defined Disorder 38 1.1 1.1 no signal
883 Head Discomfort 11 1.1 1.1 no signal
884 Pallor 17 1.1 1.1 no signal
885 Myelodysplastic Syndrome 9 1.1 1.1 no signal
886 Feeling Abnormal 149 1.1 1.1 no signal
887 Myocarditis 7 1.1 1.1 no signal
888 Parkinsonism 6 1.0 1.0 no signal
889 Gallbladder Disorder 11 1.0 1.0 no signal
890 Product Use In Unapproved Indication 150 1.0 1.0 no signal
891 Intentional Drug Misuse 13 1.0 1.0 no signal
892 Drug Ineffective 805 1.0 1.0 no signal
893 Migraine 58 1.0 1.0 no signal
894 Bedridden 8 1.0 1.0 no signal
895 Eating Disorder 13 1.0 1.0 no signal
896 Illness 61 1.0 1.0 no signal
897 Incorrect Route Of Drug Administration 22 1.0 1.0 no signal
898 Infusion Related Reaction 40 1.0 1.0 no signal
899 Lacrimation Increased 18 1.0 1.0 no signal
900 Abnormal Behaviour 24 1.0 1.0 no signal
901 Ageusia 15 1.0 1.0 no signal
902 Upper Limb Fracture 12 1.0 1.0 no signal
903 Inappropriate Schedule Of Product Administration 106 1.0 1.0 no signal
904 Brain Injury 6 1.0 1.0 no signal
905 Vaginal Discharge 6 1.0 1.0 no signal
906 Memory Impairment 82 1.0 1.0 no signal
907 Quality Of Life Decreased 8 1.0 1.0 no signal
908 Lymphadenopathy 21 1.0 1.0 no signal
909 Fear 16 1.0 1.0 no signal
910 Photophobia 11 1.0 1.0 no signal
911 Skin Lesion 16 1.0 1.0 no signal
912 Hepatitis 15 1.0 1.0 no signal
913 Muscle Rigidity 7 1.0 1.0 no signal
914 Abdominal Pain Upper 120 1.0 1.0 no signal
915 Glossodynia 13 1.0 1.0 no signal
916 Folliculitis 6 1.0 1.0 no signal
917 Drug Dispensing Error 9 1.0 1.0 no signal
918 Spinal Operation 7 1.0 1.0 no signal
919 Paranoia 10 1.0 1.0 no signal
920 Cholestasis 11 1.0 1.0 no signal
921 Chromaturia 13 1.0 1.0 no signal
922 Oral Discomfort 8 1.0 1.0 no signal
923 Skeletal Injury 6 1.0 1.0 no signal
924 Lip Swelling 19 1.0 1.0 no signal
925 Drug Dependence 93 1.0 1.0 no signal
926 Hereditary Angioedema 6 1.0 1.0 no signal
927 Transfusion 6 1.0 1.0 no signal
928 Drug Effect Incomplete 21 1.0 1.0 no signal
929 Rash 247 1.0 1.0 no signal
930 Diarrhoea 366 1.0 1.0 no signal
931 Ear Infection 15 1.0 1.0 no signal
932 Tinnitus 26 1.0 1.0 no signal
933 Retching 12 1.0 1.0 no signal
934 Muscle Twitching 13 1.0 1.0 no signal
935 Drug Dose Omission 94 1.0 1.0 no signal
936 Malignant Neoplasm Progression 57 1.0 1.0 no signal
937 Pharyngitis Streptococcal 6 0.9 0.9 no signal
938 Blood Bilirubin Increased 15 0.9 0.9 no signal
939 Abdominal Pain Lower 14 0.9 0.9 no signal
940 Off Label Use 477 0.9 0.9 no signal
941 Gastrointestinal Pain 6 0.9 0.9 no signal
942 Photosensitivity Reaction 9 0.9 0.9 no signal
943 Injection Site Haematoma 8 0.9 0.9 no signal
944 Drug Resistance 14 0.9 0.9 no signal
945 Mobility Decreased 39 0.9 0.9 no signal
946 Osteonecrosis 18 0.9 0.9 no signal
947 Multiple Fractures 9 0.9 0.9 no signal
948 Wrong Technique In Drug Usage Process 20 0.9 0.9 no signal
949 Vertigo 33 0.9 0.9 no signal
950 Red Blood Cell Sedimentation Rate Increased 6 0.9 0.9 no signal
951 Product Prescribing Issue 11 0.9 0.9 no signal
952 Diplopia 14 0.9 0.9 no signal
953 Tooth Disorder 12 0.9 0.9 no signal
954 Erythema Multiforme 5 0.9 0.9 no signal
955 Platelet Count Increased 7 0.9 0.9 no signal
956 Hepatic Cirrhosis 10 0.9 0.9 no signal
957 Breast Cancer 50 0.9 0.9 no signal
958 Peritonitis 11 0.9 0.9 no signal
959 Proteinuria 10 0.9 0.9 no signal
960 Inflammation 27 0.9 0.9 no signal
961 Internal Haemorrhage 6 0.9 0.9 no signal
962 Thrombocytopenia 58 0.9 0.9 no signal
963 Metastases To Lung 6 0.9 0.9 no signal
964 Nightmare 18 0.9 0.9 no signal
965 Dyskinesia 21 0.9 0.9 no signal
966 Colitis Ulcerative 23 0.9 0.9 no signal
967 Knee Operation 5 0.9 0.9 no signal
968 Oral Herpes 10 0.9 0.9 no signal
969 Drug Prescribing Error 10 0.9 0.9 no signal
970 Skin Disorder 17 0.9 0.9 no signal
971 Hospice Care 5 0.9 0.9 no signal
972 Platelet Count Decreased 54 0.9 0.9 no signal
973 Bone Density Decreased 16 0.9 0.9 no signal
974 Erectile Dysfunction 13 0.9 0.9 no signal
975 Abscess 8 0.9 0.9 no signal
976 Feeding Disorder 10 0.9 0.9 no signal
977 Rash Pruritic 27 0.9 0.9 no signal
978 Disturbance In Attention 27 0.8 0.8 no signal
979 Sedation 13 0.8 0.8 no signal
980 Coordination Abnormal 7 0.8 0.8 no signal
981 Rash Maculo-papular 11 0.8 0.8 no signal
982 Liver Injury 12 0.8 0.8 no signal
983 Pruritus 186 0.8 0.8 no signal
984 Helicobacter Infection 5 0.8 0.8 no signal
985 Initial Insomnia 5 0.8 0.8 no signal
986 Ear Discomfort 5 0.8 0.8 no signal
987 Paraesthesia Oral 7 0.8 0.8 no signal
988 Eye Swelling 18 0.8 0.8 no signal
989 Pancytopenia 27 0.8 0.8 no signal
990 Emotional Disorder 15 0.8 0.8 no signal
991 Neoplasm Malignant 32 0.8 0.8 no signal
992 Hospitalisation 73 0.8 0.8 no signal
993 Colitis 18 0.8 0.8 no signal
994 Muscle Atrophy 6 0.8 0.8 no signal
995 Gastrointestinal Disorder 42 0.8 0.8 no signal
996 Eructation 9 0.8 0.8 no signal
997 Face Oedema 8 0.8 0.8 no signal
998 Exposure During Pregnancy 29 0.8 0.8 no signal
999 Scar 8 0.8 0.8 no signal
1000 Musculoskeletal Discomfort 8 0.8 0.8 no signal
1001 Irritability 28 0.8 0.8 no signal
1002 Flushing 47 0.8 0.8 no signal
1003 Pulmonary Thrombosis 5 0.8 0.8 no signal
1004 Eye Disorder 15 0.8 0.8 no signal
1005 Tardive Dyskinesia 13 0.8 0.8 no signal
1006 Death 387 0.8 0.8 no signal
1007 Sars-cov-2 Test Positive 6 0.8 0.8 no signal
1008 Nerve Injury 5 0.8 0.8 no signal
1009 Visual Impairment 55 0.8 0.8 no signal
1010 Eye Infection 5 0.8 0.8 no signal
1011 Intestinal Perforation 5 0.8 0.8 no signal
1012 Uveitis 6 0.8 0.8 no signal
1013 Blindness 18 0.8 0.8 no signal
1014 Incorrect Dose Administered 98 0.7 0.7 no signal
1015 Prostatic Specific Antigen Increased 6 0.7 0.7 no signal
1016 Blood Glucose Abnormal 8 0.7 0.7 no signal
1017 Foetal Exposure During Pregnancy 35 0.7 0.7 no signal
1018 Poisoning Deliberate 4 0.7 0.7 no signal
1019 Stomatitis 26 0.7 0.7 no signal
1020 Erythema 87 0.7 0.7 no signal
1021 Serotonin Syndrome 8 0.7 0.7 no signal
1022 Drug Administration Error 13 0.7 0.7 no signal
1023 Skin Haemorrhage 6 0.7 0.7 no signal
1024 Skin Discolouration 19 0.7 0.7 no signal
1025 Hepatic Enzyme Increased 28 0.7 0.7 no signal
1026 Breast Cancer Female 11 0.7 0.7 no signal
1027 Inflammatory Bowel Disease 4 0.7 0.7 no signal
1028 Rash Erythematous 19 0.7 0.7 no signal
1029 Inappropriate Schedule Of Drug Administration 29 0.7 0.7 no signal
1030 Device Malfunction 27 0.7 0.7 no signal
1031 Rash Papular 9 0.7 0.7 no signal
1032 Extrapyramidal Disorder 10 0.7 0.7 no signal
1033 Psoriasis 52 0.7 0.7 no signal
1034 Glycosylated Haemoglobin Increased 10 0.7 0.7 no signal
1035 Injection Site Swelling 30 0.7 0.7 no signal
1036 Toxic Skin Eruption 4 0.7 0.7 no signal
1037 Dry Eye 19 0.7 0.7 no signal
1038 Expired Product Administered 13 0.7 0.7 no signal
1039 Eye Discharge 4 0.7 0.7 no signal
1040 Hot Flush 29 0.7 0.7 no signal
1041 Basal Cell Carcinoma 6 0.7 0.7 no signal
1042 Product Prescribing Error 9 0.6 0.6 no signal
1043 Diabetic Ketoacidosis 9 0.6 0.6 no signal
1044 Eye Haemorrhage 5 0.6 0.6 no signal
1045 Thinking Abnormal 7 0.6 0.6 no signal
1046 Skin Exfoliation 31 0.6 0.6 no signal
1047 Flatulence 21 0.6 0.6 no signal
1048 Hair Texture Abnormal 5 0.6 0.6 no signal
1049 Fracture 7 0.6 0.6 no signal
1050 White Blood Cell Count Decreased 40 0.6 0.6 no signal
1051 Product Use Issue 68 0.6 0.6 no signal
1052 Haematochezia 20 0.6 0.6 no signal
1053 Application Site Rash 5 0.6 0.6 no signal
1054 Circumstance Or Information Capable Of Leading To Medication Error 12 0.6 0.6 no signal
1055 Crying 13 0.6 0.6 no signal
1056 Disease Progression 42 0.6 0.6 no signal
1057 Lymphopenia 5 0.6 0.6 no signal
1058 Anger 12 0.6 0.6 no signal
1059 Pregnancy 7 0.6 0.6 no signal
1060 Device Delivery System Issue 9 0.6 0.6 no signal
1061 Palmar-plantar Erythrodysaesthesia Syndrome 8 0.6 0.6 no signal
1062 Emotional Distress 41 0.6 0.6 no signal
1063 Rheumatoid Arthritis 38 0.6 0.6 no signal
1064 Cerebral Haemorrhage 12 0.6 0.6 no signal
1065 Tooth Loss 7 0.6 0.6 no signal
1066 Product Dose Omission 22 0.6 0.6 no signal
1067 Neutropenia 45 0.6 0.6 no signal
1068 Alopecia 65 0.6 0.6 no signal
1069 Pelvic Pain 6 0.6 0.6 no signal
1070 Schizophrenia 4 0.6 0.6 no signal
1071 Surgery 19 0.6 0.6 no signal
1072 Skin Cancer 7 0.6 0.6 no signal
1073 Agranulocytosis 6 0.6 0.6 no signal
1074 Libido Decreased 4 0.5 0.5 no signal
1075 Acute Myeloid Leukaemia 5 0.5 0.5 no signal
1076 Leukopenia 16 0.5 0.5 no signal
1077 Injection Site Extravasation 4 0.5 0.5 no signal
1078 Hair Colour Changes 4 0.5 0.5 no signal
1079 Covid-19 56 0.5 0.5 no signal
1080 Underdose 23 0.5 0.5 no signal
1081 Musculoskeletal Disorder 6 0.5 0.5 no signal
1082 Mood Swings 10 0.5 0.5 no signal
1083 Injection Site Pain 95 0.5 0.5 no signal
1084 Product Availability Issue 7 0.5 0.5 no signal
1085 Therapeutic Response Unexpected 14 0.5 0.5 no signal
1086 Affect Lability 3 0.5 0.5 no signal
1087 Thrombotic Microangiopathy 3 0.5 0.5 no signal
1088 Device Defective 5 0.5 0.5 no signal
1089 Coeliac Disease 3 0.5 0.5 no signal
1090 Inability To Afford Medication 3 0.5 0.5 no signal
1091 Eye Irritation 17 0.5 0.5 no signal
1092 Mania 5 0.5 0.5 no signal
1093 Menorrhagia 6 0.5 0.5 no signal
1094 Pain Of Skin 8 0.5 0.5 no signal
1095 Device Occlusion 4 0.5 0.5 no signal
1096 Gynaecomastia 9 0.5 0.5 no signal
1097 Rash Macular 10 0.5 0.5 no signal
1098 Intentional Product Use Issue 25 0.5 0.5 no signal
1099 Vaginal Haemorrhage 12 0.5 0.5 no signal
1100 Breast Cancer Metastatic 3 0.5 0.5 no signal
1101 Extra Dose Administered 11 0.5 0.5 no signal
1102 Therapy Interrupted 19 0.5 0.5 no signal
1103 Product Packaging Quantity Issue 3 0.5 0.5 no signal
1104 Injection Site Pruritus 18 0.5 0.5 no signal
1105 Fistula 3 0.5 0.5 no signal
1106 Exposure Via Skin Contact 6 0.5 0.5 no signal
1107 Product Substitution Issue 15 0.4 0.4 no signal
1108 Withdrawal Syndrome 11 0.4 0.4 no signal
1109 Madarosis 3 0.4 0.4 no signal
1110 Dry Skin 33 0.4 0.4 no signal
1111 Thyroid Cancer 3 0.4 0.4 no signal
1112 Hepatitis C 3 0.4 0.4 no signal
1113 Pemphigus 3 0.4 0.4 no signal
1114 Abnormal Weight Gain 3 0.4 0.4 no signal
1115 Injection Site Irritation 3 0.4 0.4 no signal
1116 Gastric Cancer 6 0.4 0.4 no signal
1117 Neoplasm Progression 8 0.4 0.4 no signal
1118 Therapeutic Product Effect Decreased 10 0.4 0.4 no signal
1119 Incorrect Product Storage 3 0.4 0.4 no signal
1120 Application Site Pruritus 5 0.4 0.4 no signal
1121 No Adverse Event 39 0.4 0.4 no signal
1122 Treatment Failure 18 0.4 0.4 no signal
1123 Injection Site Reaction 15 0.4 0.4 no signal
1124 Wrong Technique In Product Usage Process 44 0.4 0.4 no signal
1125 Drug Ineffective For Unapproved Indication 12 0.4 0.4 no signal
1126 Pancreatic Carcinoma 6 0.4 0.4 no signal
1127 Plasma Cell Myeloma 8 0.3 0.3 no signal
1128 Abortion Spontaneous 8 0.3 0.3 no signal
1129 Intentional Self-injury 4 0.3 0.3 no signal
1130 Injection Site Rash 6 0.3 0.3 no signal
1131 Injection Site Warmth 4 0.3 0.3 no signal
1132 Injection Site Bruising 15 0.3 0.3 no signal
1133 Injection Site Mass 7 0.3 0.3 no signal
1134 Injection Site Erythema 22 0.3 0.3 no signal
1135 Device Use Error 6 0.3 0.3 no signal
1136 Metrorrhagia 3 0.3 0.3 no signal
1137 Drug Effective For Unapproved Indication 5 0.3 0.3 no signal
1138 Drug Withdrawal Syndrome 15 0.3 0.3 no signal
1139 Injection Site Urticaria 4 0.3 0.3 no signal
1140 Product Complaint 4 0.3 0.3 no signal
1141 Acne 12 0.3 0.3 no signal
1142 Application Site Erythema 4 0.3 0.3 no signal
1143 Injury Associated With Device 3 0.3 0.3 no signal
1144 Multiple Sclerosis 7 0.2 0.2 no signal
1145 Renal Cancer 7 0.2 0.2 no signal
1146 Incorrect Drug Administration Duration 4 0.2 0.2 no signal
1147 Device Issue 12 0.2 0.2 no signal
1148 Oesophageal Carcinoma 4 0.2 0.2 no signal
1149 Injection Site Haemorrhage 10 0.2 0.2 no signal
1150 Bladder Cancer 7 0.2 0.2 no signal
1151 Menstruation Irregular 3 0.2 0.2 no signal
1152 Product Adhesion Issue 4 0.2 0.2 no signal
1153 Accidental Exposure To Product 11 0.2 0.2 no signal
1154 Drug Dose Omission By Device 8 0.2 0.2 no signal
1155 Device Breakage 4 0.2 0.2 no signal
1156 Prostate Cancer 6 0.1 0.1 no signal