Reaction

Prolonged Expiration reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 261 reports · 34 co-occurring drugs

As of the last recalculation, Prolonged Expiration appears in 261 FAERS reports alongside 34 co-occurring drug terms. The strongest observed disproportionality signal is QUINAPRIL HYDROCHLORIDE (PRR 804.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Quinapril Hydrochloride	61	804.4	810.7
Dimenhydrinate	60	582.8	586.1
Theophylline	60	540.3	543.1
Theophylline Anhydrous	62	522.7	525.4
Diltiazem Hydrochloride Extended-Release Tablets	49	422.6	424.4
Nitrofurantoin	57	352.4	353.6
Nitrofurantoin (Monohydrate/Macrocrystals)	57	347.8	349.0
Mepolizumab	100	259.6	260.1
Insulin Degludec	57	247.5	248.1
Ipratropium Bromide	74	230.5	231.0
Mometasone	39	199.2	199.6
Amitriptyline Hydrochloride	32	165.6	165.9
Fluticasone Propionate And Salmeterol Xinafoate	84	164.0	164.2
Tiotropium Bromide Inhalation Spray	21	162.4	162.7
Diltiazem Hydrochloride	50	142.3	142.5
Lactulose	54	141.4	141.6
Montelukast Sodium	117	138.1	138.2
Loperamide Hydrochloride Oral	15	124.2	124.4
Nitroglycerin	58	110.6	110.7
Cyanocobalamin	38	107.5	107.6
Mometasone Furoate	46	106.7	106.8
Azithromycin	43	101.8	101.9
Loperamide Hcl	15	98.6	98.7
Azithromycin Monohydrate	43	98.4	98.5
Tiotropium Bromide	92	82.2	82.2
Fluticasone Furoate And Vilanterol Trifenatate	31	77.9	77.9
Azelastine	14	65.6	65.7
Metformin Hydrochloride Tablets	40	65.5	65.6
Metformin Hydrochloride Extended-Release Tablets	40	65.5	65.6
Metformin Hydrochloride Tablet	40	65.5	65.5
Insulin Aspart	44	63.6	63.7
Metformin Hydrochloride	40	63.5	63.5
Fluoxetine	44	63.1	63.1
Sildenafil	33	51.9	51.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.