OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Vismodegib

692 flagged reaction(s) · 22,122 total co-reports · max PRR 849.9
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Basal Cell Carcinoma Metastatic 4 849.9 850.3 signal
2 Basal Cell Naevus Syndrome 3 369.0 369.1 signal
3 Atrophic Glossitis 8 187.0 187.1 signal
4 Skin Neoplasm Bleeding 3 140.2 140.3 signal
5 Ageusia 1,011 99.8 112.6 signal
6 Medulloblastoma 6 98.8 98.8 signal
7 Malignant Neoplasm Of Eye 11 94.9 95.0 signal
8 Entropion 5 80.0 80.1 signal
9 Medulloblastoma Recurrent 3 63.7 63.8 signal
10 Hypogeusia 48 59.5 59.8 signal
11 Pancreatic Duct Obstruction 4 54.7 54.7 signal
12 Epiphyses Premature Fusion 5 40.3 40.3 signal
13 Pancreas Infection 6 36.1 36.2 signal
14 Nasal Neoplasm 4 35.8 35.8 signal
15 Eye Excision 3 35.1 35.1 signal
16 Ear Neoplasm Malignant 3 29.8 29.8 signal
17 Hypotrichosis 8 29.4 29.4 signal
18 Taste Disorder 240 28.7 29.5 signal
19 Squamous Cell Carcinoma 111 28.2 28.6 signal
20 Muscle Spasms 2,065 27.0 34.8 signal
21 Bone Development Abnormal 3 25.0 25.0 signal
22 Poor Dental Condition 3 24.3 24.4 signal
23 Dysgeusia 747 23.9 26.0 signal
24 Vascular Stent Stenosis 4 23.0 23.0 signal
25 Ectropion 3 21.4 21.4 signal
26 Basal Cell Carcinoma 140 21.4 21.8 signal
27 Metastatic Squamous Cell Carcinoma 4 18.7 18.7 signal
28 Alopecia 1,401 17.0 20.0 signal
29 Tumour Pain 9 16.2 16.2 signal
30 Ocular Neoplasm 3 15.0 15.1 signal
31 Telangiectasia 6 15.0 15.0 signal
32 Ingrown Hair 4 14.0 14.0 signal
33 Acquired Gene Mutation 7 12.6 12.6 signal
34 Madarosis 60 12.2 12.3 signal
35 Recurrent Cancer 20 11.7 11.8 signal
36 Tumour Haemorrhage 14 11.7 11.7 signal
37 Enterocolitis Infectious 4 10.2 10.2 signal
38 Bone Cyst 4 10.1 10.1 signal
39 Hair Growth Abnormal 29 10.0 10.0 signal
40 Paraparesis 7 9.3 9.3 signal
41 Actinic Keratosis 10 9.1 9.1 signal
42 Cholestatic Liver Injury 8 8.9 8.9 signal
43 Ocular Vascular Disorder 3 8.6 8.6 signal
44 Spinal Cord Neoplasm 3 8.1 8.1 signal
45 Anosmia 48 7.9 7.9 signal
46 Embolism 27 7.7 7.7 signal
47 Malignant Melanoma In Situ 4 7.5 7.5 signal
48 Cancer Surgery 3 7.5 7.5 signal
49 Neuroendocrine Carcinoma Of The Skin 3 7.3 7.3 signal
50 Decreased Appetite 706 7.2 7.8 signal
51 Neoplasm 33 6.8 6.8 signal
52 Squamous Cell Carcinoma Of Skin 17 6.7 6.7 signal
53 Hyposmia 4 6.5 6.5 signal
54 Hypophosphataemia 20 6.5 6.5 signal
55 Weight Decreased 738 6.3 6.8 signal
56 Cell Death 5 6.0 6.0 signal
57 Bile Duct Stenosis 3 5.9 5.9 signal
58 Hepatic Infection 3 5.6 5.6 signal
59 Metastatic Neoplasm 10 5.5 5.5 signal
60 Exposure Via Father 3 5.4 5.4 signal
61 Haematological Infection 5 5.1 5.1 signal
62 Appetite Disorder 14 5.1 5.1 signal
63 Diffuse Alopecia 4 5.1 5.1 signal
64 Muscle Fatigue 9 5.1 5.1 signal
65 Blood Electrolytes Decreased 3 5.0 5.0 signal
66 Ulcer Haemorrhage 13 4.6 4.6 signal
67 Duodenal Ulcer 13 4.4 4.4 signal
68 Lymphocyte Count Decreased 31 4.2 4.2 signal
69 Constipation 379 4.2 4.3 signal
70 Metastatic Malignant Melanoma 4 4.1 4.1 signal
71 Urinary Tract Obstruction 4 4.0 4.0 signal
72 Dysentery 3 3.8 3.8 no signal
73 Melanocytic Naevus 7 3.8 3.8 signal
74 Hepatotoxicity 34 3.6 3.6 signal
75 Nasal Disorder 4 3.6 3.6 signal
76 Ear Haemorrhage 3 3.5 3.5 no signal
77 Neoplasm Recurrence 5 3.5 3.5 signal
78 No Adverse Event 258 3.5 3.5 signal
79 Deafness 38 3.4 3.5 signal
80 Hypoalbuminaemia 11 3.4 3.4 signal
81 Cd4 Lymphocytes Decreased 3 3.3 3.3 no signal
82 Pharyngeal Disorder 4 3.3 3.3 signal
83 Tongue Disorder 10 3.3 3.3 signal
84 Sensory Loss 11 3.2 3.2 signal
85 Neutrophil Count Decreased 55 3.2 3.2 signal
86 Skin Cancer 29 3.2 3.2 signal
87 Malignant Melanoma 18 3.2 3.2 signal
88 Myelofibrosis 4 3.1 3.1 no signal
89 Face Injury 5 3.1 3.1 signal
90 Bilirubin Conjugated Increased 3 3.1 3.1 no signal
91 Myalgia 218 3.0 3.1 signal
92 Intercepted Medication Error 6 3.0 3.0 signal
93 Non-cardiac Chest Pain 4 3.0 3.0 no signal
94 Fatigue 970 3.0 3.2 signal
95 Rash Vesicular 6 3.0 3.0 signal
96 Radius Fracture 3 2.9 2.9 no signal
97 Feeding Disorder 24 2.9 2.9 signal
98 Parosmia 9 2.8 2.8 signal
99 Metastases To Spine 4 2.8 2.8 no signal
100 Appendicitis Perforated 3 2.8 2.8 no signal
101 Intentional Product Use Issue 104 2.8 2.8 signal
102 Abdominal Infection 3 2.8 2.8 no signal
103 Intercepted Product Storage Error 4 2.8 2.8 no signal
104 Cancer Pain 3 2.8 2.8 no signal
105 Hepatitis Toxic 3 2.7 2.7 no signal
106 Amenorrhoea 19 2.7 2.7 signal
107 Ileus 14 2.7 2.7 signal
108 Jaundice 30 2.6 2.6 signal
109 Macule 3 2.6 2.6 no signal
110 Ill-defined Disorder 65 2.5 2.5 signal
111 Hyponatraemia 60 2.5 2.5 signal
112 Yellow Skin 5 2.5 2.5 no signal
113 Joint Lock 3 2.5 2.5 no signal
114 Retinal Vein Occlusion 3 2.5 2.5 no signal
115 Cholestasis 20 2.5 2.5 signal
116 Blood Alkaline Phosphatase Increased 26 2.5 2.5 signal
117 Pulmonary Pain 3 2.5 2.5 no signal
118 Lung Cancer Metastatic 3 2.5 2.5 no signal
119 Blood Magnesium Decreased 9 2.5 2.5 signal
120 Paraplegia 3 2.5 2.5 no signal
121 Liver Function Test Increased 22 2.4 2.4 signal
122 Gastrointestinal Sounds Abnormal 5 2.4 2.4 no signal
123 Hepatitis Cholestatic 6 2.4 2.4 no signal
124 Acne Cystic 3 2.4 2.4 no signal
125 Dermatitis Acneiform 6 2.4 2.4 no signal
126 Gastric Disorder 34 2.3 2.3 signal
127 Cachexia 5 2.3 2.3 no signal
128 Dehydration 130 2.3 2.3 signal
129 Dementia 27 2.3 2.3 signal
130 Failure To Thrive 5 2.3 2.3 no signal
131 Blood Sodium Decreased 18 2.3 2.3 signal
132 Tongue Discomfort 4 2.3 2.3 no signal
133 Hypophagia 24 2.2 2.2 signal
134 Neoplasm Malignant 63 2.2 2.2 signal
135 Blood Creatine Phosphokinase Increased 27 2.2 2.2 signal
136 Lipase Increased 7 2.2 2.2 no signal
137 Bone Cancer 4 2.2 2.2 no signal
138 Nausea 714 2.1 2.2 signal
139 Hip Fracture 29 2.1 2.1 signal
140 Salivary Hypersecretion 9 2.1 2.1 signal
141 Hepatic Enzyme Increased 61 2.1 2.1 signal
142 Facial Pain 8 2.1 2.1 no signal
143 Disease Progression 105 2.1 2.1 signal
144 Abnormal Loss Of Weight 6 2.1 2.1 no signal
145 Scab 10 2.1 2.1 signal
146 B-cell Lymphoma 3 2.1 2.1 no signal
147 Onychoclasis 6 2.1 2.1 no signal
148 Renal Function Test Abnormal 4 2.1 2.1 no signal
149 Death 750 2.1 2.2 signal
150 Brain Neoplasm 8 2.1 2.1 no signal
151 Micturition Disorder 3 2.1 2.1 no signal
152 Mass 12 2.0 2.0 signal
153 Dysphagia 81 2.0 2.0 signal
154 Urine Odour Abnormal 5 2.0 2.0 no signal
155 Musculoskeletal Chest Pain 13 2.0 2.0 no signal
156 Food Intolerance 3 1.9 1.9 no signal
157 Hair Texture Abnormal 11 1.9 1.9 no signal
158 Wound Haemorrhage 3 1.9 1.9 no signal
159 Cyst 10 1.9 1.9 no signal
160 Therapy Cessation 40 1.9 1.9 no signal
161 Electrolyte Imbalance 9 1.9 1.9 no signal
162 Asthenia 294 1.9 1.9 no signal
163 Hyperbilirubinaemia 8 1.8 1.8 no signal
164 Skin Ulcer 20 1.8 1.8 no signal
165 Folliculitis 8 1.8 1.8 no signal
166 Hepatitis Acute 5 1.8 1.8 no signal
167 Epigastric Discomfort 3 1.8 1.8 no signal
168 Coronavirus Infection 5 1.8 1.8 no signal
169 Eating Disorder 16 1.8 1.8 no signal
170 Intracranial Aneurysm 3 1.8 1.8 no signal
171 Muscle Disorder 6 1.7 1.7 no signal
172 Hiccups 6 1.7 1.7 no signal
173 Diarrhoea 472 1.7 1.8 no signal
174 Small Intestinal Obstruction 9 1.7 1.7 no signal
175 International Normalised Ratio Increased 21 1.7 1.7 no signal
176 Deafness Unilateral 4 1.7 1.7 no signal
177 Onychomadesis 3 1.7 1.7 no signal
178 Gastric Ulcer Haemorrhage 4 1.7 1.7 no signal
179 Thermal Burn 5 1.7 1.7 no signal
180 Metastasis 5 1.7 1.7 no signal
181 Arthralgia 283 1.6 1.6 no signal
182 Haemoglobin Increased 3 1.6 1.6 no signal
183 Joint Dislocation 7 1.6 1.6 no signal
184 Chromaturia 15 1.6 1.6 no signal
185 Drug Resistance 17 1.6 1.6 no signal
186 Cholangitis 4 1.5 1.5 no signal
187 Hypercalcaemia 8 1.5 1.5 no signal
188 Muscle Atrophy 8 1.5 1.5 no signal
189 Lung Infection 10 1.5 1.5 no signal
190 Transaminases Increased 14 1.5 1.5 no signal
191 Tooth Loss 13 1.5 1.5 no signal
192 Guillain-barre Syndrome 3 1.5 1.5 no signal
193 Muscle Tightness 10 1.5 1.5 no signal
194 Metastases To Lung 7 1.4 1.4 no signal
195 Hyperglycaemia 22 1.4 1.4 no signal
196 Walking Aid User 4 1.4 1.4 no signal
197 Hepatic Enzyme Abnormal 3 1.4 1.4 no signal
198 Metastases To Lymph Nodes 4 1.4 1.4 no signal
199 Cystitis 19 1.4 1.4 no signal
200 Pregnancy 12 1.4 1.4 no signal
201 Abdominal Pain Upper 120 1.4 1.4 no signal
202 Hypoacusis 25 1.4 1.4 no signal
203 Oral Pain 13 1.4 1.4 no signal
204 Gastric Ulcer 11 1.4 1.4 no signal
205 Large Intestine Perforation 4 1.4 1.4 no signal
206 Blood Calcium Increased 5 1.3 1.3 no signal
207 Abdominal Discomfort 95 1.3 1.4 no signal
208 Groin Pain 5 1.3 1.3 no signal
209 Ulcer 9 1.3 1.3 no signal
210 Blood Bilirubin Increased 15 1.3 1.3 no signal
211 Aspiration 6 1.3 1.3 no signal
212 Vomiting 259 1.3 1.3 no signal
213 Gastrointestinal Pain 6 1.3 1.3 no signal
214 Intestinal Ischaemia 3 1.3 1.3 no signal
215 Hepatitis 14 1.3 1.3 no signal
216 Liver Function Test Abnormal 16 1.3 1.3 no signal
217 Urosepsis 5 1.3 1.3 no signal
218 Dyspepsia 53 1.3 1.3 no signal
219 Cholecystitis Acute 3 1.3 1.3 no signal
220 Troponin Increased 4 1.3 1.3 no signal
221 Mouth Swelling 3 1.2 1.2 no signal
222 Drug-induced Liver Injury 16 1.2 1.2 no signal
223 Retching 11 1.2 1.2 no signal
224 Peripheral Sensory Neuropathy 3 1.2 1.2 no signal
225 Blood Iron Decreased 6 1.2 1.2 no signal
226 Aspartate Aminotransferase Increased 27 1.2 1.2 no signal
227 Odynophagia 3 1.2 1.2 no signal
228 Hypomagnesaemia 7 1.2 1.2 no signal
229 Lethargy 29 1.2 1.2 no signal
230 Cardiac Pacemaker Insertion 3 1.2 1.2 no signal
231 White Blood Cell Count Decreased 54 1.2 1.2 no signal
232 Gamma-glutamyltransferase Increased 11 1.2 1.2 no signal
233 Dry Throat 5 1.2 1.2 no signal
234 Shock Haemorrhagic 4 1.2 1.2 no signal
235 Hypersomnia 14 1.2 1.2 no signal
236 Hyperaesthesia 4 1.1 1.1 no signal
237 Incontinence 5 1.1 1.1 no signal
238 Anaemia 90 1.1 1.1 no signal
239 Facial Paralysis 4 1.1 1.1 no signal
240 White Blood Cell Count Abnormal 3 1.1 1.1 no signal
241 Oral Mucosal Blistering 3 1.1 1.1 no signal
242 Mental Status Changes 13 1.1 1.1 no signal
243 Hernia 9 1.1 1.1 no signal
244 White Blood Cell Count Increased 18 1.1 1.1 no signal
245 Gastrointestinal Disorder 41 1.1 1.1 no signal
246 Faeces Discoloured 10 1.1 1.1 no signal
247 Flatulence 26 1.1 1.1 no signal
248 Thrombosis 37 1.1 1.1 no signal
249 Pulmonary Thrombosis 5 1.1 1.1 no signal
250 Dry Mouth 37 1.1 1.1 no signal
251 Urine Output Decreased 4 1.1 1.1 no signal
252 Cellulitis 23 1.1 1.1 no signal
253 Blood Count Abnormal 7 1.1 1.1 no signal
254 Arteriosclerosis Coronary Artery 3 1.1 1.1 no signal
255 Malnutrition 5 1.1 1.1 no signal
256 Lung Infiltration 4 1.1 1.1 no signal
257 Pharyngeal Oedema 7 1.1 1.1 no signal
258 Pancreatitis Acute 10 1.1 1.1 no signal
259 Blindness 18 1.0 1.0 no signal
260 Maternal Exposure Before Pregnancy 3 1.0 1.0 no signal
261 Skin Lesion 12 1.0 1.0 no signal
262 Hypertransaminasaemia 3 1.0 1.0 no signal
263 Rib Fracture 9 1.0 1.0 no signal
264 Hypokalaemia 20 1.0 1.0 no signal
265 Cerebrovascular Accident 74 1.0 1.0 no signal
266 Muscle Twitching 10 1.0 1.0 no signal
267 Off Label Use 375 1.0 1.0 no signal
268 Amnesia 28 1.0 1.0 no signal
269 Blindness Unilateral 6 1.0 1.0 no signal
270 Colitis 16 1.0 1.0 no signal
271 Arteriosclerosis 4 1.0 1.0 no signal
272 Fracture 8 1.0 1.0 no signal
273 Hepatocellular Injury 6 1.0 1.0 no signal
274 Sepsis 47 1.0 1.0 no signal
275 Fall 140 1.0 1.0 no signal
276 Urinary Tract Infection 71 1.0 1.0 no signal
277 Paraesthesia Oral 6 1.0 1.0 no signal
278 Faeces Soft 3 1.0 1.0 no signal
279 Bone Pain 24 1.0 1.0 no signal
280 Immunodeficiency 6 1.0 1.0 no signal
281 Alanine Aminotransferase Increased 25 1.0 1.0 no signal
282 Pain 248 1.0 1.0 no signal
283 Hypoaesthesia Oral 6 0.9 0.9 no signal
284 Hair Colour Changes 5 0.9 0.9 no signal
285 Blood Creatinine Increased 26 0.9 0.9 no signal
286 Sluggishness 4 0.9 0.9 no signal
287 Aortic Aneurysm 3 0.9 0.9 no signal
288 Aphthous Ulcer 3 0.9 0.9 no signal
289 Insomnia 104 0.9 0.9 no signal
290 Erectile Dysfunction 10 0.9 0.9 no signal
291 Lymphoma 6 0.9 0.9 no signal
292 Abdominal Pain 90 0.9 0.9 no signal
293 Joint Stiffness 10 0.9 0.9 no signal
294 Myasthenia Gravis 3 0.9 0.9 no signal
295 Sciatica 6 0.9 0.9 no signal
296 Gastrooesophageal Reflux Disease 30 0.9 0.9 no signal
297 Intestinal Obstruction 14 0.9 0.9 no signal
298 Increased Appetite 7 0.9 0.9 no signal
299 Wound Infection 4 0.9 0.9 no signal
300 Back Disorder 6 0.9 0.9 no signal
301 Malaise 161 0.9 0.9 no signal
302 Menstrual Disorder 3 0.9 0.9 no signal
303 Musculoskeletal Disorder 7 0.9 0.9 no signal
304 Blood Potassium Decreased 11 0.9 0.9 no signal
305 Photosensitivity Reaction 6 0.9 0.9 no signal
306 Drug Intolerance 35 0.9 0.9 no signal
307 Dental Caries 4 0.9 0.9 no signal
308 Liver Disorder 16 0.9 0.9 no signal
309 Muscular Weakness 41 0.9 0.9 no signal
310 Skin Disorder 12 0.9 0.9 no signal
311 Ear Pain 7 0.9 0.9 no signal
312 Hair Disorder 3 0.9 0.9 no signal
313 Wound 10 0.9 0.9 no signal
314 Therapy Non-responder 16 0.9 0.9 no signal
315 Aphonia 5 0.8 0.8 no signal
316 Skin Infection 4 0.8 0.8 no signal
317 Platelet Count Decreased 38 0.8 0.8 no signal
318 Eye Infection 4 0.8 0.8 no signal
319 Hypoaesthesia 53 0.8 0.8 no signal
320 Haematocrit Decreased 7 0.8 0.8 no signal
321 Upper Limb Fracture 7 0.8 0.8 no signal
322 Internal Haemorrhage 4 0.8 0.8 no signal
323 Haematoma 9 0.8 0.8 no signal
324 Gastritis 9 0.8 0.8 no signal
325 Pancreatitis 18 0.8 0.8 no signal
326 Back Pain 79 0.8 0.8 no signal
327 Lung Neoplasm Malignant 14 0.8 0.8 no signal
328 Myositis 3 0.8 0.8 no signal
329 Drug Interaction 53 0.8 0.8 no signal
330 Mouth Ulceration 7 0.8 0.8 no signal
331 Limb Injury 9 0.8 0.8 no signal
332 Therapy Partial Responder 5 0.8 0.8 no signal
333 Glomerular Filtration Rate Decreased 4 0.8 0.8 no signal
334 Pneumonia Bacterial 3 0.8 0.8 no signal
335 Poor Quality Sleep 7 0.8 0.8 no signal
336 Rhinorrhoea 21 0.8 0.8 no signal
337 Diverticulitis 9 0.8 0.8 no signal
338 Speech Disorder 17 0.8 0.8 no signal
339 Rash 140 0.8 0.8 no signal
340 Feeling Cold 9 0.8 0.8 no signal
341 Cognitive Disorder 15 0.8 0.8 no signal
342 Blister 18 0.8 0.8 no signal
343 Atrial Fibrillation 31 0.8 0.8 no signal
344 Abdominal Distension 33 0.8 0.8 no signal
345 Melaena 7 0.8 0.8 no signal
346 Pain In Extremity 93 0.7 0.7 no signal
347 Lower Limb Fracture 6 0.7 0.7 no signal
348 Stevens-johnson Syndrome 7 0.7 0.7 no signal
349 Acute Respiratory Failure 6 0.7 0.7 no signal
350 Memory Impairment 43 0.7 0.7 no signal
351 Pancreatic Carcinoma 9 0.7 0.7 no signal
352 Syncope 31 0.7 0.7 no signal
353 Hiatus Hernia 4 0.7 0.7 no signal
354 Blood Potassium Increased 5 0.7 0.7 no signal
355 Nephrolithiasis 14 0.7 0.7 no signal
356 Musculoskeletal Pain 16 0.7 0.7 no signal
357 Adverse Reaction 4 0.7 0.7 no signal
358 Headache 187 0.7 0.7 no signal
359 Illness 30 0.7 0.7 no signal
360 Depression 68 0.7 0.7 no signal
361 Blood Urea Increased 5 0.7 0.7 no signal
362 Confusional State 48 0.7 0.7 no signal
363 Upper Gastrointestinal Haemorrhage 5 0.7 0.7 no signal
364 Pneumonitis 8 0.7 0.7 no signal
365 Transient Ischaemic Attack 10 0.7 0.7 no signal
366 Acute Hepatic Failure 4 0.7 0.7 no signal
367 Eye Discharge 3 0.7 0.7 no signal
368 Pulmonary Embolism 28 0.7 0.7 no signal
369 Neutrophil Count Increased 3 0.7 0.7 no signal
370 Myocardial Infarction 51 0.7 0.7 no signal
371 Acne 22 0.7 0.7 no signal
372 Prostatic Specific Antigen Increased 4 0.7 0.7 no signal
373 Orthostatic Hypotension 5 0.7 0.7 no signal
374 Pruritus 108 0.7 0.7 no signal
375 Hereditary Angioedema 3 0.7 0.7 no signal
376 Lymphopenia 4 0.7 0.7 no signal
377 Renal Pain 3 0.7 0.7 no signal
378 Clostridium Difficile Colitis 3 0.7 0.7 no signal
379 Pneumonia 91 0.7 0.7 no signal
380 Thirst 5 0.7 0.7 no signal
381 Peripheral Swelling 43 0.7 0.7 no signal
382 Decreased Activity 3 0.7 0.7 no signal
383 Night Sweats 9 0.7 0.7 no signal
384 Red Blood Cell Count Decreased 8 0.7 0.7 no signal
385 Subdural Haematoma 4 0.7 0.7 no signal
386 Body Height Decreased 3 0.7 0.7 no signal
387 Pharyngitis Streptococcal 3 0.7 0.7 no signal
388 Laryngitis 3 0.7 0.7 no signal
389 Therapy Interrupted 19 0.7 0.7 no signal
390 Apathy 4 0.7 0.7 no signal
391 C-reactive Protein Increased 10 0.7 0.7 no signal
392 Cholelithiasis 9 0.6 0.6 no signal
393 Musculoskeletal Stiffness 24 0.6 0.6 no signal
394 Gastrointestinal Haemorrhage 23 0.6 0.6 no signal
395 Seizure 31 0.6 0.6 no signal
396 Nerve Injury 3 0.6 0.6 no signal
397 Pulmonary Mass 4 0.6 0.6 no signal
398 Colon Cancer 4 0.6 0.6 no signal
399 Lacrimation Increased 8 0.6 0.6 no signal
400 Renal Impairment 22 0.6 0.6 no signal
401 Dizziness 130 0.6 0.6 no signal
402 Frequent Bowel Movements 7 0.6 0.6 no signal
403 Pain Of Skin 7 0.6 0.6 no signal
404 Cardiac Failure Congestive 21 0.6 0.6 no signal
405 Limb Discomfort 8 0.6 0.6 no signal
406 Haemorrhage 27 0.6 0.6 no signal
407 Hyperkalaemia 9 0.6 0.6 no signal
408 Mood Altered 7 0.6 0.6 no signal
409 Choking 5 0.6 0.6 no signal
410 Swelling 24 0.6 0.6 no signal
411 Neoplasm Progression 9 0.6 0.6 no signal
412 Rash Erythematous 12 0.6 0.6 no signal
413 Swollen Tongue 8 0.6 0.6 no signal
414 Bacteraemia 3 0.6 0.6 no signal
415 Covid-19 45 0.6 0.6 no signal
416 Lymphadenopathy 9 0.6 0.6 no signal
417 Neuropathy Peripheral 24 0.6 0.6 no signal
418 Disease Recurrence 12 0.6 0.6 no signal
419 Arthropathy 14 0.6 0.6 no signal
420 Localised Infection 6 0.6 0.6 no signal
421 Metastases To Bone 4 0.6 0.6 no signal
422 General Physical Health Deterioration 28 0.6 0.6 no signal
423 Cough 68 0.6 0.6 no signal
424 Libido Decreased 3 0.6 0.6 no signal
425 Dermatitis 5 0.6 0.6 no signal
426 Arthritis 19 0.6 0.6 no signal
427 Expired Product Administered 8 0.6 0.6 no signal
428 Pneumonia Aspiration 6 0.6 0.6 no signal
429 Urinary Retention 8 0.6 0.6 no signal
430 Candida Infection 4 0.6 0.6 no signal
431 Dysphonia 14 0.6 0.6 no signal
432 Visual Acuity Reduced 8 0.6 0.6 no signal
433 Ascites 7 0.6 0.6 no signal
434 Type 2 Diabetes Mellitus 8 0.6 0.6 no signal
435 Pyrexia 82 0.6 0.6 no signal
436 Cardiac Failure 19 0.6 0.6 no signal
437 Infection 34 0.6 0.6 no signal
438 Dry Skin 31 0.6 0.6 no signal
439 Renal Disorder 11 0.6 0.6 no signal
440 Impaired Gastric Emptying 3 0.6 0.6 no signal
441 Joint Injury 5 0.6 0.6 no signal
442 Respiratory Disorder 7 0.6 0.6 no signal
443 Thrombocytopenia 26 0.6 0.6 no signal
444 Hepatic Failure 7 0.5 0.5 no signal
445 Aphasia 7 0.5 0.5 no signal
446 Clostridium Difficile Infection 5 0.5 0.5 no signal
447 Chronic Obstructive Pulmonary Disease 12 0.5 0.5 no signal
448 Influenza Like Illness 19 0.5 0.5 no signal
449 Somnolence 46 0.5 0.5 no signal
450 Rash Generalised 6 0.5 0.5 no signal
451 Hypoxia 8 0.5 0.5 no signal
452 Heart Rate Decreased 8 0.5 0.5 no signal
453 Ear Infection 6 0.5 0.5 no signal
454 Herpes Zoster 13 0.5 0.5 no signal
455 Rash Maculo-papular 5 0.5 0.5 no signal
456 Incorrect Product Storage 3 0.5 0.5 no signal
457 Surgery 13 0.5 0.5 no signal
458 Renal Failure 30 0.5 0.5 no signal
459 Ischaemic Stroke 4 0.5 0.5 no signal
460 Cardiac Disorder 21 0.5 0.5 no signal
461 Quality Of Life Decreased 3 0.5 0.5 no signal
462 Osteomyelitis 4 0.5 0.5 no signal
463 Restless Legs Syndrome 4 0.5 0.5 no signal
464 Skin Discolouration 10 0.5 0.5 no signal
465 Rhabdomyolysis 9 0.5 0.5 no signal
466 Malignant Neoplasm Progression 22 0.5 0.5 no signal
467 Irritability 13 0.5 0.5 no signal
468 Oral Discomfort 3 0.5 0.5 no signal
469 Bronchitis 16 0.5 0.5 no signal
470 Middle Insomnia 4 0.5 0.5 no signal
471 Hepatic Steatosis 4 0.5 0.5 no signal
472 Palmar-plantar Erythrodysaesthesia Syndrome 5 0.5 0.5 no signal
473 Blood Test Abnormal 3 0.5 0.5 no signal
474 Eye Disorder 7 0.5 0.5 no signal
475 Coordination Abnormal 3 0.5 0.5 no signal
476 Thinking Abnormal 4 0.5 0.5 no signal
477 Epistaxis 16 0.5 0.5 no signal
478 Gait Inability 7 0.5 0.5 no signal
479 Staphylococcal Infection 7 0.5 0.5 no signal
480 Viral Infection 7 0.5 0.5 no signal
481 Foot Fracture 4 0.5 0.5 no signal
482 Cardiogenic Shock 3 0.5 0.5 no signal
483 Paralysis 3 0.5 0.5 no signal
484 Blood Pressure Fluctuation 5 0.5 0.5 no signal
485 Glaucoma 4 0.5 0.5 no signal
486 Nasopharyngitis 38 0.5 0.5 no signal
487 Brain Fog 3 0.5 0.5 no signal
488 Haemorrhoids 4 0.5 0.5 no signal
489 Lung Disorder 10 0.5 0.5 no signal
490 Kidney Infection 4 0.5 0.5 no signal
491 Visual Impairment 25 0.5 0.5 no signal
492 Dyspnoea 114 0.5 0.5 no signal
493 Drug Effect Decreased 11 0.5 0.5 no signal
494 Product Administration Error 4 0.5 0.5 no signal
495 Sleep Disorder 14 0.5 0.5 no signal
496 Stomatitis 12 0.5 0.5 no signal
497 Drug Dose Omission 33 0.5 0.5 no signal
498 Paraesthesia 31 0.5 0.5 no signal
499 Febrile Neutropenia 13 0.5 0.5 no signal
500 Product Dose Omission 13 0.5 0.5 no signal
501 Blood Pressure Decreased 13 0.5 0.5 no signal
502 Peritonitis 4 0.5 0.5 no signal
503 Ejection Fraction Decreased 3 0.5 0.5 no signal
504 Respiratory Tract Infection 5 0.5 0.5 no signal
505 Diplopia 5 0.5 0.5 no signal
506 Mucosal Inflammation 5 0.5 0.5 no signal
507 Knee Arthroplasty 4 0.5 0.5 no signal
508 Productive Cough 9 0.5 0.4 no signal
509 Dysuria 7 0.4 0.4 no signal
510 Pneumothorax 3 0.4 0.4 no signal
511 Arrhythmia 9 0.4 0.4 no signal
512 Hallucination, Auditory 3 0.4 0.4 no signal
513 Abscess 3 0.4 0.4 no signal
514 Mood Swings 6 0.4 0.4 no signal
515 Gait Disturbance 36 0.4 0.4 no signal
516 Chills 22 0.4 0.4 no signal
517 Movement Disorder 6 0.4 0.4 no signal
518 Cataract 11 0.4 0.4 no signal
519 Burning Sensation 13 0.4 0.4 no signal
520 Hypotension 37 0.4 0.4 no signal
521 Therapeutic Product Effect Incomplete 13 0.4 0.4 no signal
522 Deep Vein Thrombosis 12 0.4 0.4 no signal
523 Chest Pain 34 0.4 0.4 no signal
524 Skin Burning Sensation 13 0.4 0.4 no signal
525 Impaired Healing 6 0.4 0.4 no signal
526 Respiratory Distress 5 0.4 0.4 no signal
527 Multiple Fractures 3 0.4 0.4 no signal
528 Therapeutic Product Effect Decreased 8 0.4 0.4 no signal
529 Medication Error 10 0.4 0.4 no signal
530 Tooth Disorder 4 0.4 0.4 no signal
531 Neck Pain 10 0.4 0.4 no signal
532 Hospitalisation 27 0.4 0.4 no signal
533 Hemiparesis 3 0.4 0.4 no signal
534 Vision Blurred 24 0.4 0.4 no signal
535 Haemoglobin Decreased 18 0.4 0.4 no signal
536 Hypertension 37 0.4 0.4 no signal
537 Tremor 29 0.4 0.4 no signal
538 Balance Disorder 15 0.4 0.4 no signal
539 Intentional Product Misuse 15 0.4 0.4 no signal
540 Unevaluable Event 13 0.4 0.4 no signal
541 Eosinophilia 3 0.4 0.4 no signal
542 Blood Cholesterol Increased 8 0.4 0.4 no signal
543 Multi-organ Failure 3 0.4 0.4 no signal
544 Dysstasia 5 0.4 0.4 no signal
545 Diabetes Mellitus 13 0.4 0.4 no signal
546 Acute Respiratory Distress Syndrome 3 0.4 0.4 no signal
547 Diabetes Mellitus Inadequate Control 3 0.4 0.4 no signal
548 Blood Triglycerides Increased 3 0.4 0.4 no signal
549 Swelling Face 11 0.4 0.4 no signal
550 Urinary Incontinence 5 0.4 0.4 no signal
551 Gout 3 0.4 0.4 no signal
552 Leukocytosis 3 0.4 0.4 no signal
553 Toothache 3 0.4 0.4 no signal
554 Interstitial Lung Disease 8 0.4 0.4 no signal
555 Liver Injury 4 0.4 0.4 no signal
556 Sinusitis 17 0.4 0.4 no signal
557 Mental Impairment 4 0.4 0.4 no signal
558 Loss Of Consciousness 21 0.4 0.4 no signal
559 Bone Disorder 3 0.4 0.4 no signal
560 Hepatic Function Abnormal 6 0.4 0.4 no signal
561 Bacterial Infection 3 0.4 0.4 no signal
562 Photophobia 3 0.4 0.4 no signal
563 Mental Disorder 7 0.4 0.4 no signal
564 Nervous System Disorder 5 0.4 0.4 no signal
565 Dysarthria 6 0.4 0.4 no signal
566 Skin Fissures 3 0.4 0.4 no signal
567 Haematemesis 4 0.4 0.4 no signal
568 Drug Reaction With Eosinophilia And Systemic Symptoms 4 0.4 0.4 no signal
569 Contusion 15 0.4 0.4 no signal
570 Inflammation 8 0.4 0.4 no signal
571 Oral Herpes 3 0.4 0.4 no signal
572 Feeling Abnormal 37 0.4 0.4 no signal
573 Stress 11 0.4 0.4 no signal
574 Tinnitus 7 0.4 0.4 no signal
575 Influenza 17 0.4 0.4 no signal
576 Disorientation 6 0.4 0.4 no signal
577 Abnormal Behaviour 6 0.4 0.4 no signal
578 Product Storage Error 13 0.4 0.4 no signal
579 Urticaria 25 0.4 0.4 no signal
580 Product Dose Omission In Error 4 0.4 0.4 no signal
581 Drug Ineffective 195 0.4 0.3 no signal
582 Disturbance In Attention 8 0.4 0.3 no signal
583 Anger 5 0.3 0.3 no signal
584 Erythema 30 0.3 0.3 no signal
585 Hypoglycaemia 7 0.3 0.3 no signal
586 Pollakiuria 6 0.3 0.3 no signal
587 Anxiety 41 0.3 0.3 no signal
588 Rash Macular 5 0.3 0.3 no signal
589 Oropharyngeal Pain 13 0.3 0.3 no signal
590 Cerebral Haemorrhage 5 0.3 0.3 no signal
591 Pruritus Generalised 3 0.3 0.3 no signal
592 Prostate Cancer 11 0.3 0.3 no signal
593 Acute Myocardial Infarction 4 0.3 0.3 no signal
594 Throat Irritation 6 0.3 0.3 no signal
595 Glossodynia 3 0.3 0.3 no signal
596 Sneezing 3 0.3 0.3 no signal
597 Hallucination 10 0.3 0.3 no signal
598 Skin Exfoliation 11 0.3 0.3 no signal
599 Heart Rate Irregular 3 0.3 0.3 no signal
600 Acute Kidney Injury 20 0.3 0.3 no signal
601 Vertigo 8 0.3 0.3 no signal
602 Blood Pressure Increased 20 0.3 0.3 no signal
603 Plasma Cell Myeloma 5 0.3 0.3 no signal
604 Head Injury 4 0.3 0.3 no signal
605 Hypothyroidism 4 0.3 0.3 no signal
606 Dry Eye 6 0.3 0.3 no signal
607 Product Dose Omission Issue 35 0.3 0.3 no signal
608 Lip Swelling 4 0.3 0.3 no signal
609 Fungal Infection 4 0.3 0.3 no signal
610 Road Traffic Accident 5 0.3 0.3 no signal
611 Hot Flush 9 0.3 0.3 no signal
612 Circumstance Or Information Capable Of Leading To Medication Error 4 0.3 0.3 no signal
613 Hyperhidrosis 15 0.3 0.3 no signal
614 Discomfort 7 0.3 0.3 no signal
615 Nightmare 4 0.3 0.3 no signal
616 Nervousness 6 0.3 0.3 no signal
617 Menstruation Irregular 3 0.3 0.3 no signal
618 Throat Tightness 3 0.3 0.3 no signal
619 Oedema 6 0.3 0.3 no signal
620 Treatment Noncompliance 6 0.3 0.3 no signal
621 Respiratory Failure 8 0.3 0.3 no signal
622 Eye Pain 6 0.3 0.3 no signal
623 Eye Swelling 4 0.3 0.3 no signal
624 Joint Swelling 13 0.3 0.3 no signal
625 Abnormal Dreams 3 0.3 0.3 no signal
626 Weight Increased 24 0.3 0.3 no signal
627 Oxygen Saturation Decreased 6 0.3 0.3 no signal
628 Multiple Organ Dysfunction Syndrome 3 0.3 0.3 no signal
629 Breast Cancer 10 0.3 0.3 no signal
630 Angina Pectoris 3 0.2 0.2 no signal
631 Blood Glucose Decreased 5 0.2 0.2 no signal
632 Nasal Congestion 6 0.2 0.2 no signal
633 Heart Rate Increased 10 0.2 0.2 no signal
634 Extra Dose Administered 4 0.2 0.2 no signal
635 Osteoporosis 4 0.2 0.2 no signal
636 Drug Administration Error 3 0.2 0.2 no signal
637 Agitation 7 0.2 0.2 no signal
638 Renal Failure Acute 4 0.2 0.2 no signal
639 Rash Pruritic 5 0.2 0.2 no signal
640 Eye Pruritus 3 0.2 0.2 no signal
641 Angioedema 4 0.2 0.2 no signal
642 Adverse Drug Reaction 8 0.2 0.2 no signal
643 Pulmonary Oedema 4 0.2 0.2 no signal
644 Lower Respiratory Tract Infection 4 0.2 0.2 no signal
645 Chest Discomfort 9 0.2 0.2 no signal
646 Haematuria 3 0.2 0.2 no signal
647 Upper Respiratory Tract Infection 4 0.2 0.2 no signal
648 Ocular Hyperaemia 4 0.2 0.2 no signal
649 Palpitations 10 0.2 0.2 no signal
650 Accidental Overdose 3 0.2 0.2 no signal
651 Oedema Peripheral 10 0.2 0.2 no signal
652 Feeling Hot 5 0.2 0.2 no signal
653 Hypersensitivity 15 0.2 0.2 no signal
654 Blood Glucose Increased 15 0.2 0.2 no signal
655 Suicidal Ideation 7 0.2 0.2 no signal
656 Depressed Mood 4 0.2 0.2 no signal
657 Dyskinesia 3 0.2 0.2 no signal
658 Neutropenia 10 0.2 0.2 no signal
659 Eye Irritation 4 0.2 0.2 no signal
660 Injury 5 0.2 0.2 no signal
661 Septic Shock 3 0.2 0.2 no signal
662 Tachycardia 6 0.2 0.2 no signal
663 Chronic Kidney Disease 5 0.2 0.2 no signal
664 Multiple Sclerosis 3 0.1 0.1 no signal
665 Treatment Failure 5 0.1 0.1 no signal
666 Cardiac Arrest 5 0.1 0.1 no signal
667 Toxicity To Various Agents 10 0.1 0.1 no signal
668 Fluid Retention 3 0.1 0.1 no signal
669 Product Use In Unapproved Indication 14 0.1 0.1 no signal
670 Anaphylactic Reaction 3 0.1 0.1 no signal
671 Haematochezia 3 0.1 0.1 no signal
672 Pancytopenia 3 0.1 0.1 no signal
673 Drug Ineffective For Unapproved Indication 3 0.1 0.1 no signal
674 Convulsion 3 0.1 0.1 no signal
675 Bladder Cancer 3 0.1 0.1 no signal
676 Therapeutic Response Decreased 3 0.1 0.1 no signal
677 Wrong Technique In Product Usage Process 10 0.1 0.1 no signal
678 Suicide Attempt 3 0.1 0.1 no signal
679 Psoriasis 6 0.1 0.1 no signal
680 Inappropriate Schedule Of Product Administration 8 0.1 0.1 no signal
681 Mobility Decreased 3 0.1 0.1 no signal
682 Drug Hypersensitivity 8 0.1 0.1 no signal
683 Emotional Distress 5 0.1 0.1 no signal
684 Condition Aggravated 11 0.1 0.1 no signal
685 Completed Suicide 3 0.1 0.1 no signal
686 Rheumatoid Arthritis 4 0.1 0.1 no signal
687 Incorrect Dose Administered 7 0.1 0.1 no signal
688 Flushing 3 0.1 0.1 no signal
689 Overdose 6 0.1 0.1 no signal
690 Asthma 3 0.1 0.1 no signal
691 Product Quality Issue 3 0.1 0.1 no signal
692 Product Use Issue 4 0.1 0.1 no signal