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Which drugs are most reported with Duodenal ulcer?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,963 reports · 379 co-occurring drugs

As of the last recalculation, Duodenal Ulcer appears in 6,963 FAERS reports alongside 379 co-occurring drug terms. The strongest observed disproportionality signal is QUININE (PRR 15.1).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Quinine	43	15.1	15.1
Naproxen Sodium Tablet, Coated	50	11.1	11.1
Naproxen Sodium, Coated Tablets	50	11.1	11.1
Naproxen Sodium 220Mg	50	11.1	11.1
Naproxen	272	10.7	10.8
Diclofenac	296	10.7	10.7
Acetaminophen And Codeine	41	10.1	10.1
Diltiazem Hydrochloride Extended-Release Tablets	37	9.8	9.8
Olmesartan Medoxomil	113	9.5	9.6
Diclofenac Sodium 1%	111	9.4	9.4
Diclofenac Sodium Topical	111	9.4	9.4
Diclofenac Sodium Topical Gel, 1%	111	9.4	9.4
Nitrofurantoin	48	8.8	8.8
Ibuprofen 200Mg	542	8.7	8.7
Ibuprofen Capsule	541	8.7	8.7
Ibuprofen Tablet, Film Coated	541	8.7	8.7
Ibupfrofen	541	8.7	8.7
Ibuprofen Tablets Usp, 200Mg	541	8.7	8.7
Ibuprofen Oral	541	8.7	8.7
Ibuprofen Capsules 200 Mg	541	8.7	8.7
Ibuprofen 200 Mg	541	8.7	8.7
Nitrofurantoin (Monohydrate/Macrocrystals)	48	8.6	8.7
Indomethacin	37	8.4	8.4
Diclofenac Sodium	396	8.3	8.3
Indapamide	49	8.2	8.2
Clopidogrel Bisulfate	256	7.7	7.7
Thiamine Hydrochloride	32	7.7	7.7
Naproxen Sodium	352	7.7	7.7
Dalteparin Sodium	27	7.7	7.7
Ibuprofen	603	7.2	7.2
Temazepam	89	7.1	7.1
Atovaquone	19	7.1	7.1
Ketoprofen	30	6.9	6.9
Isosorbide Mononitrate	47	6.8	6.8
Fondaparinux Sodium	18	6.7	6.7
Felodipine Extended-Release Tablets	25	6.6	6.6
Felodipine	25	6.6	6.6
Cefazolin	20	6.6	6.6
Dexamethasone Sodium Phosphate	22	6.5	6.5
Cefazolin Sodium	25	6.2	6.2
Meperidine Hydrochloride	19	6.2	6.2
Pseudoephedrine Hydrochloride	21	6.1	6.1
Sucralfate	48	6.0	6.0
Apixaban	130	5.9	5.9
Clopidogrel	372	5.9	5.9
Pseudoephedrine Hcl	21	5.7	5.7
Aspirin 325 Mg	868	5.7	5.7
Aspirin 81 Mg	868	5.6	5.7
Sorafenib	39	5.6	5.6
Octreotide Acetate	57	5.6	5.6
Cimetidine	18	5.6	5.6
Aspirin	889	5.5	5.5
Encorafenib	18	5.4	5.5
Piperacillin Sodium,Tazobactam Sodium	47	5.3	5.3
Febuxostat Tablets 40 Mg	18	5.3	5.3
Febuxostat Tablets 80 Mg	18	5.3	5.3
Captopril	17	5.3	5.3
Bisoprolol Fumarate	230	5.2	5.2
Leucovorin Calcium	32	5.0	5.0
Ramipril	199	4.9	4.9
Cortisone Acetate	20	4.9	4.9
Heparin Sodium	22	4.8	4.8
Donepezil Hydrochloride	58	4.8	4.8
Sennosides 8.6 Mg Tablets	33	4.7	4.7
Ticagrelor	50	4.7	4.7
Nebivolol	25	4.7	4.7
Senna	33	4.7	4.7
Sirolimus	21	4.7	4.7
Irinotecan Hydrochloride	20	4.7	4.7
Deferasirox	41	4.6	4.6
Sucralfate Oral	22	4.6	4.6
Sucralfate Oral Suspension	22	4.6	4.6
Doxazosin	43	4.6	4.6
Oxaliplatin	113	4.6	4.6
Tofacitinib Citrate	20	4.6	4.6
Senna Leaf	35	4.6	4.6
Ursodiol	33	4.5	4.6
Fluorouracil Cream, 0.5%	114	4.5	4.5
Lactulose	57	4.5	4.5
Fluorouracil	114	4.5	4.5
Meloxicam	85	4.4	4.4
Vismodegib	13	4.4	4.4
Bevacizumab	177	4.4	4.4
Mycophenilic Acid	30	4.3	4.3
Dolutegravir Sodium	13	4.3	4.3
Gefitinib	13	4.3	4.3
Ceftriaxone	47	4.3	4.3
Atezolizumab	55	4.3	4.3
Piperacillin And Tazobactam	18	4.2	4.2
Digoxin	100	4.2	4.2
Dapagliflozin	44	4.2	4.2
Loperamide Hcl	18	4.2	4.2
Diltiazem Hydrochloride	48	4.2	4.2
Doxazosin Mesylate	50	4.2	4.2
Warfarin Sodium	64	4.2	4.2
Prasugrel Hydrochloride	14	4.1	4.1
Lenvatinib	45	4.1	4.1
Candesartan Cilexetil	36	4.1	4.1
Erlotinib Hydrochloride	17	4.1	4.1
Candesartan	48	4.0	4.0
Telmisartan	24	4.0	4.0
Sennosides	40	4.0	4.0
Erlotinib	13	4.0	4.0
Ceftriaxone Sodium	51	4.0	4.0
Lopinavir And Ritonavir	18	4.0	4.0
Pertuzumab	36	4.0	4.0
Piperacillin Sodium And Tazobactam Sodium	26	4.0	4.0
Risedronate Sodium	41	4.0	4.0
Abiraterone	18	4.0	4.0
Cetuximab	41	3.9	3.9
Enoxaparin Sodium	75	3.9	3.9
Enalapril Maleate	32	3.9	3.9
Cisplatin	99	3.8	3.8
Loperamide Hydrochloride Oral	13	3.8	3.8
Pitavastatin Calcium	13	3.8	3.8
Enalapril	70	3.8	3.8
Nitroglycerin	67	3.8	3.8
Warfarin	157	3.8	3.8
Febuxostat	21	3.8	3.8
Prednisolone	220	3.7	3.7
Prednisolone Oral	220	3.7	3.7
Prednisolone Oral Solution	220	3.7	3.7
Atenolol	163	3.7	3.7
Rivaroxaban	252	3.7	3.7
Dimenhydrinate	13	3.7	3.7
Valsartan Oral	65	3.6	3.6
Clarithromycin	41	3.6	3.6
Pazopanib Hydrochloride	32	3.5	3.5
Rizatriptan Benzoate	12	3.5	3.5
Spironolactone	162	3.5	3.5
Rivastigmine	22	3.5	3.5
Acetylcysteine	11	3.5	3.5
Simvastatin	283	3.5	3.5
Gemcitabine Hydrochloride	61	3.5	3.5
Propofol	42	3.5	3.5
Docetaxel Anhydrous	77	3.4	3.4
Docetaxel	77	3.4	3.4
Panitumumab	18	3.4	3.4
Baricitinib	11	3.4	3.4
Ursosiol	22	3.4	3.4
Promethazine Hydrochloride	21	3.4	3.4
Misoprostol	11	3.4	3.4
Celecoxib	144	3.3	3.3
Polyethylene Glycol	12	3.3	3.3
Basiliximab	13	3.3	3.3
Diphenoxylate Hydrochloride And Atropine Sulfate	15	3.3	3.3
Eplerenone	14	3.3	3.3
Fexofenadine Hcl	10	3.2	3.2
Glimepiride	42	3.2	3.2
Pembrolizumab	112	3.2	3.2
Ganciclovir	11	3.2	3.2
Mycophenolic Acid	34	3.2	3.2
Gemfibrozil	16	3.2	3.2
Desoximetasone	20	3.1	3.1
Gemcitabine	41	3.1	3.1
Midazolam Hydrochloride	28	3.1	3.1
Nebivolol Hydrochloride	35	3.1	3.1
Ganciclovir Sodium	11	3.1	3.1
Trametinib	25	3.1	3.1
Isosorbide Dinitrate	20	3.1	3.1
Azithromycin	41	3.1	3.1
Furosemide	394	3.1	3.1
Magnesium Sulfate In Water For	13	3.0	3.0
Trimethoprim	12	3.0	3.0
Valsartan	106	3.0	3.0
Lansoprazole	177	3.0	3.0
Meropenem	32	3.0	3.0
Magnesium Sulfate Heptahydrate	13	3.0	3.0
Magnesium Sulfate	13	3.0	3.0
Amlodipine Besylate And Valsartan	11	3.0	3.0
Ezetimibe	74	3.0	3.0
Azithromycin Monohydrate	41	3.0	3.0
Dutasteride	8	2.9	2.9
Leflunomide	102	2.9	2.9
Pantoprazole	242	2.9	2.9
Sitagliptin And Metformin Hydrochloride	21	2.9	2.9
Antacid	46	2.9	2.9
Clobetasol Propionate Ointment Usp, 0.05%	10	2.9	2.9
Clobetasol Propionate	10	2.9	2.9
Ampicillin	8	2.9	2.9
Ampicillin Sodium	8	2.9	2.9
Ibuprofen Sodium	41	2.9	2.9
Fluticasone Propionate Nasal	29	2.9	2.9
Ranolazine	10	2.9	2.9
Amlodipine Besylate	138	2.9	2.9
Methylprednisolone	130	2.8	2.8
Ibuprofen Tablets, Coated	40	2.8	2.8
Phytonadione	8	2.8	2.8
Entecavir	11	2.8	2.8
Salmeterol Xinafoate	8	2.8	2.8
Metformin Hcl	51	2.8	2.8
Allopurinol	142	2.7	2.8
Acetaminophen Tablet Extended Release	229	2.7	2.7
Pain Reliever	229	2.7	2.7
Insulin Glargine-Yfgn	20	2.7	2.7
Acetaminophen 500Mg	229	2.7	2.7
Capecitabine	83	2.7	2.7
Citalopram Hydrobromide	97	2.7	2.7
Glyburide	22	2.7	2.7
Trastuzumab	62	2.7	2.7
Torsemide	30	2.7	2.7
Dabrafenib	19	2.7	2.7
Tranexamic Acid	8	2.7	2.7
Carboplatin	113	2.7	2.7
Irbesartan	40	2.7	2.7
Loperamide Hydrochloride	40	2.7	2.7
Metronidazole	57	2.7	2.7
Magnesium Oxide	37	2.7	2.7
Paclitaxel (Aibumin-Bound)	72	2.6	2.6
Calcium Carbonate	58	2.6	2.6
Sitagliptin	62	2.6	2.6
Granisetron Hydrochloride	9	2.6	2.6
Ipilimumab	37	2.6	2.6
Atorvastatin Calcium, Film Coated	60	2.6	2.6
Mycophenolate Mofetil	115	2.6	2.6
Dabigatran Etexilate	66	2.6	2.6
Paclitaxel	84	2.6	2.6
Mycophenolate Mofetil Hydrochloride	115	2.6	2.6
Hydrocortisone Sodium Succinate	8	2.5	2.5
Lubiprostone	8	2.5	2.5
Dabigatran Etexilate Mesylate	61	2.5	2.5
Ipratropium Bromide	30	2.5	2.5
Norepinephrine	9	2.5	2.5
Pemetrexed Disodium	32	2.5	2.5
Everolimus Tablets	14	2.5	2.5
Budesonide	49	2.5	2.5
Midazolam	21	2.5	2.5
Sarilumab	22	2.5	2.5
Finasteride	50	2.5	2.5
Atorvastatin Calcium	202	2.5	2.5
Rotigotine	12	2.5	2.5
Amoxicillin	63	2.5	2.5
Metoroprolol Tartrate	54	2.5	2.5
Metronidazole Topical	39	2.5	2.5
Citalopram	110	2.4	2.4
Tenofovir Disoproxil Fumarate Tablets	7	2.4	2.4
Amoxicillin And Clavulanate Potassium	22	2.4	2.4
Insulin	45	2.4	2.4
Rasagiline Mesylate	9	2.4	2.4
Timolol Maleate	8	2.4	2.4
Azithromycin Dihydrate	47	2.4	2.4
Pantoprazole Sodium	118	2.4	2.4
Nivolumab	77	2.4	2.4
Metolazone	9	2.4	2.4
Omeprazole	270	2.4	2.4
Pemetrexed	17	2.4	2.4
Metoprolol Tartrate	213	2.4	2.4
Carvedilol	106	2.4	2.4
Tacrolimus	122	2.4	2.4
Esomeprazole Magnesium	181	2.3	2.3
Tamsulosin Hydrochloride	16	2.3	2.3
Loperamide Hydrochloride And Dimethicone	25	2.3	2.3
Esomeprazole	48	2.3	2.3
Lapatinib	12	2.3	2.3
Metoprolol	193	2.3	2.3
Omeprazole Magnesium	335	2.3	2.3
Linagliptin	14	2.3	2.3
Fentanyl	75	2.3	2.3
Nifedipine	36	2.3	2.3
Tacrolimus Ointment 0.1%	94	2.3	2.3
Prochlorperazine Maleate	7	2.3	2.3
Pravastatin Sodium	15	2.3	2.3
Tacrolimus Extended-Release Capsules	94	2.3	2.3
Naproxen Sodium Tablet	40	2.3	2.3
Metoclopramide Hydrochloride	58	2.3	2.3
Amlodipine	199	2.2	2.2
Vemurafenib	9	2.2	2.2
Calcitriol Capsules 0.25 Mcg	15	2.2	2.2
Calcitriol Capsules 0.5 Mcg	15	2.2	2.2
Cholestyramine	9	2.2	2.2
Lovastatin	19	2.2	2.2
Metoprolol Tartrate Injection	139	2.2	2.2
Calcitriol	15	2.2	2.2
Nintedanib	23	2.2	2.2
Rabeprazole Sodium	20	2.2	2.2
Metformin	256	2.2	2.2
Ibuprofen And Diphenhydramine Citrate	17	2.2	2.2
Vancomycin	42	2.2	2.2
Doxycycline Hyclate	49	2.2	2.2
Fosaprepitant Dimeglumine	10	2.2	2.2
Metformin Er 500 Mg	215	2.2	2.2
Metformin Er 750 Mg	215	2.2	2.2
Mesna Injection	6	2.2	2.2
Doxycycline	49	2.2	2.2
Ferrous Sulfate	36	2.1	2.1
Metformin Hydrochloride Tablets	41	2.1	2.1
Metformin Hydrochloride Extended-Release Tablets	41	2.1	2.1
Metformin Hydrochloride Tablet	41	2.1	2.1
Vancomycin Hydrochloride	47	2.1	2.1
Nilotinib	21	2.1	2.1
Mesna	6	2.1	2.1
Metformin Hydrochloride	42	2.1	2.1
Hydroxyurea	15	2.1	2.1
Rosuvastatin	142	2.1	2.1
Losartan Potassium	55	2.1	2.1
Sulfasalazine	54	2.1	2.1
Adalimumab-Fkjp	32	2.1	2.1
Valganciclovir	13	2.1	2.1
Valganciclovir Hydrochloride	13	2.1	2.1
Sunitinib Malate	27	2.1	2.1
Prochlorperazine	19	2.1	2.1
Adalimumab-Aaty	32	2.0	2.0
Metoclopramide	37	2.0	2.0
Granisetron	7	2.0	2.0
Metoprolol Succinate	57	2.0	2.0
Valganciclovir Hydrochloride Powder,	8	2.0	2.0
Propranolol Hydrochloride	47	2.0	2.0
Aprepitant	12	1.9	1.9
Amlodipine Besylate And Benazepril Hydrochloride	6	1.9	1.9
Adalimumab-Adaz	34	1.9	1.9
Fludarabine Phosphate	25	1.9	1.9
Methoxy Polyethylene Glycol-Epoetin Beta	7	1.9	1.9
Abiraterone Acetate	26	1.9	1.9
Thiotepa	6	1.9	1.9
Efavirenz	7	1.9	1.9
Norepinephrine Bitartrate	9	1.9	1.9
Lisinopril	189	1.9	1.9
Famotidine	73	1.9	1.9
Tolvaptan	9	1.9	1.9
Isoniazid	10	1.8	1.8
Abacavir Sulfate	6	1.8	1.8
Polatuzumab Vedotin	6	1.8	1.8
Sotalol Hydrochloride	10	1.8	1.8
Metoprolol Succinate Er Tablets	37	1.8	1.8
Bicalutamide	9	1.8	1.8
Everolimus	30	1.8	1.8
Dronedarone	6	1.8	1.8
Cabozantinib	28	1.7	1.7
Insulin Human	23	1.7	1.7
Cefepime Hydrochloride	9	1.7	1.7
Cefepime	8	1.7	1.7
Latanoprost	28	1.7	1.7
Bosutinib	5	1.7	1.7
Pioglitazone	24	1.7	1.7
Carbidopa And Levodopa	26	1.6	1.6
Romiplostim	8	1.6	1.6
Dexlansoprazole	22	1.6	1.6
Doxorubicin Hydrochloride	17	1.6	1.6
Regorafenib	6	1.5	1.5
Busulfan	8	1.5	1.5
Levodopa	6	1.5	1.5
Paricalcitol	7	1.5	1.5
Pancrelipase	19	1.5	1.5
Vincristine Sulfate	14	1.4	1.4
Isopropyl Alcohol	16	1.4	1.4
Acetaminophen, Aspirin (Nsaid) And Caffeine	8	1.4	1.4
Icosapent Ethyl	4	1.4	1.4
Axitinib	9	1.4	1.4
Bimatoprost	13	1.3	1.3
Brimonidine Tartrate	8	1.3	1.3
Desvenlafaxine Succinate	12	1.3	1.3
Durvalumab	9	1.3	1.3
Acetaminophen, Aspirin, And Caffeine	9	1.3	1.3
Enzalutamide	25	1.3	1.3
Axicabtagene Ciloleucel	4	1.2	1.2
Alcohol	15	1.2	1.2
Suvorexant	5	1.2	1.2
Isotretinoin	19	1.1	1.1
Ranitidine	76	1.1	1.1
Emtricitabine And Tenofovir Disoproxil Fumarate	17	1.1	1.1
Diclofenac Potassium, Film Coated	3	1.1	1.1
Diclofenac Potassium Tablets	3	1.1	1.1
Sofosbuvir	7	1.1	1.1
Ustekinumab	35	1.0	1.0
Fentanyl Citrate	6	1.0	1.0
Ranitidine Hydrochloride	18	1.0	1.0
Ledipasvir And Sofosbuvir	6	0.9	0.9
Osimertinib	10	0.9	0.9
Sacubitril And Valsartan	36	0.9	0.9
Tenofovir Disoproxil Fumarate	10	0.9	0.9
Umeclidinium Bromide And Vilanterol Trifenatate	5	0.9	0.9
Fam-Trastuzumab Deruxtecan-Nxki	3	0.9	0.9
Romosozumab-Aqqg	4	0.9	0.9
Trifluridine And Tipiracil	3	0.8	0.8
Exenatide	14	0.8	0.8
Ixazomib	7	0.7	0.7
Velpatasvir And Sofosbuvir	3	0.7	0.7
Nirmatrelvir And Ritonavir	10	0.6	0.6
Cinacalcet Hydrochloride	7	0.4	0.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.