Reaction

Actinic Keratosis reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,577 reports · 109 co-occurring drugs

As of the last recalculation, Actinic Keratosis appears in 2,577 FAERS reports alongside 109 co-occurring drug terms. The strongest observed disproportionality signal is VORICONAZOLE INJECTION (PRR 107.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Voriconazole Injection	259	107.0	108.3
Voriconazole	295	88.4	89.3
Valganciclovir	65	28.5	28.6
Valganciclovir Hydrochloride	65	28.5	28.6
Hydroxyurea	66	25.8	25.9
Amphotericin B	38	24.8	24.9
Ganciclovir	30	23.9	24.0
Ganciclovir Sodium	31	23.9	24.0
Valganciclovir Hydrochloride Powder,	35	23.5	23.5
Tacrolimus Ointment 0.1%	292	21.2	21.3
Tacrolimus Extended-Release Capsules	292	21.2	21.2
Tacrolimus	330	19.4	19.4
Everolimus Tablets	37	18.1	18.1
Vemurafenib	25	17.0	17.0
Torsemide	64	16.0	16.0
Mycophenolate Mofetil	239	15.6	15.6
Mycophenolate Mofetil Hydrochloride	239	15.5	15.6
Alendronate Sodium	181	15.5	15.5
Tamsulosin Hydrochloride	37	14.8	14.9
Candesartan	62	14.4	14.4
Ketoconazole Foam	26	14.3	14.4
Ketoconazole Cream, 2%	26	14.3	14.3
Candesartan Cilexetil	45	14.1	14.1
Nebivolol	27	13.8	13.8
Sodium Bicarbonate	39	13.7	13.8
Sodium Bicarbonate Injection,	39	13.7	13.8
Captopril	16	13.5	13.5
Chlorhexidine Gluconate	15	13.3	13.4
Sirolimus	22	13.3	13.3
Ketoconazole	27	12.7	12.7
Telmisartan	26	11.9	11.9
Mycophenolic Acid	46	11.8	11.8
Felodipine Extended-Release Tablets	16	11.4	11.4
Felodipine	16	11.4	11.4
Busulfan	22	11.4	11.4
Losartan Potassium And Hydrochlorothiazide	16	11.2	11.2
Tofacitinib Citrate	18	11.2	11.2
Doxazosin Mesylate	49	11.2	11.2
Itraconazole	16	11.1	11.1
Doxazosin	35	10.2	10.2
Azathioprine	106	10.1	10.1
Alemtuzumab	23	9.7	9.7
Azithromycin Dihydrate	68	9.6	9.6
Vismodegib	10	9.1	9.1
Chlorthalidone	13	9.1	9.1
Azithromycin	44	9.0	9.0
Nebivolol Hydrochloride	36	8.7	8.7
Risedronate Sodium	33	8.7	8.7
Azithromycin Monohydrate	44	8.7	8.7
Nifedipine	46	8.0	8.0
Mometasone	18	8.0	8.0
Meperidine Hydrochloride	9	7.9	7.9
Cephalexin	21	7.9	7.9
Valsartan Oral	52	7.9	7.9
Cyclosporine	101	7.6	7.6
Prednisolone	160	7.6	7.6
Prednisolone Oral	160	7.6	7.6
Prednisolone Oral Solution	160	7.6	7.6
Quinine	8	7.6	7.6
Mupirocin Calcium	12	7.1	7.1
Clobetasol Propionate Ointment Usp, 0.05%	9	7.1	7.1
Methylprednisolone Acetate	7	7.1	7.1
Clobetasol Propionate	9	7.1	7.1
Darbepoetin Alfa	45	6.8	6.9
Raloxifene Hydrochloride	12	6.7	6.7
Valacyclovir	34	6.7	6.7
Mupirocin	11	6.6	6.6
Hydrochlorothiazide	109	6.3	6.3
Trimethoprim	9	6.2	6.2
Everolimus	38	6.1	6.1
Secukinumab	117	6.1	6.1
Tadalafil	73	6.0	6.0
Fludarabine Phosphate	29	6.0	6.0
Simvastatin	175	6.0	6.0
Ixekizumab	26	5.7	5.7
Minoxidil Foam 5% (Womens)	23	5.7	5.7
Phenobarbital	10	5.6	5.6
Valsartan	71	5.6	5.6
Primidone	7	5.6	5.6
Minocycline	8	5.6	5.6
Fingolimod Hcl	58	5.5	5.5
Melphalan Hydrochloride	17	5.5	5.5
Terbinafine Hydrochloride	6	5.5	5.5
Melphalan	15	5.4	5.4
Bendamustine Hcl	10	5.2	5.2
Posaconazole Delayed-Release	7	5.2	5.2
Finasteride	38	5.1	5.2
Valacyclovir Hydrochloride	44	5.1	5.1
Thalidomide	23	5.1	5.1
Sorafenib	13	5.1	5.1
Sildenafil Citrate	78	5.1	5.1
Lovastatin	16	5.1	5.1
Dutasteride	5	5.0	5.0
Encorafenib	6	4.9	4.9
Timolol Maleate	6	4.9	4.9
Lisinopril And Hydrochlorothiazide	6	4.8	4.8
Timolol	7	4.7	4.7
Siponimod	5	4.5	4.5
Dabrafenib	11	4.2	4.2
Minoxidil	23	4.2	4.2
Bortezomib	41	3.7	3.7
Ruxolitinib	31	3.5	3.5
Trametinib	8	2.7	2.7
Pemetrexed	7	2.6	2.6
Bimatoprost	9	2.5	2.5
Conjugated Estrogens And Medroxyprogesterone Acetate	6	2.1	2.1
Apremilast	23	1.3	1.3
Pegfilgrastim	15	1.2	1.2
Tapentadol Hydrochloride	5	1.2	1.2

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.