Reaction

Product Container Seal Issue reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,658 reports · 24 co-occurring drugs

As of the last recalculation, Product Container Seal Issue appears in 1,658 FAERS reports alongside 24 co-occurring drug terms. The strongest observed disproportionality signal is TRAVOPROST (PRR 68.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Travoprost4668.669.0
Icosapent Ethyl1217.817.8
Brinzolamide1116.016.0
Brivaracetam1115.515.5
Latanoprost5113.113.1
Testosterone Cypionate912.712.7
Brimonidine Tartrate1611.411.4
Lifitegrast1310.110.1
Dorzolamide Hydrochloride And Timolol Maleate69.69.6
Carboxymethylcellulose Sodium68.08.0
Vibegron57.87.9
Azelastine117.77.7
Timolol Maleate67.67.6
Cannabidiol147.67.6
Bimatoprost167.07.0
Guselkumab186.46.4
Paliperidone Palmitate166.36.3
Golimumab324.84.8
Naltrexone Hydrochloride And Bupropion Hydrochloride34.44.4
Ustekinumab334.14.1
Brexpiprazole53.83.8
Emtricitabine And Tenofovir Alafenamide33.33.3
Erenumab-Aooe81.81.8
Pimavanserin Tartrate61.41.4

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.