OpenPV Signal Explorer
FAERS disproportionality dashboard
← All drugs
Drug

Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate

1,019 flagged reaction(s) · 78,006 total co-reports · max PRR 1,291.0
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Mycoplasma Genitalium Infection 9 1,291.0 1,291.7 signal
2 Abiotrophia Defectiva Endocarditis 4 918.1 918.3 signal
3 Bone Demineralisation 278 414.3 420.8 signal
4 Viral Load Abnormal 41 367.6 368.4 signal
5 Bone Loss 3,468 345.6 427.7 signal
6 Bone Density Decreased 6,622 308.4 487.1 signal
7 Skeletal Injury 2,122 296.7 336.2 signal
8 Multiple Fractures 3,147 273.4 331.1 signal
9 Tooth Loss 3,426 228.8 282.3 signal
10 Bone Density Abnormal 467 164.5 168.8 signal
11 Osteopenia 1,881 163.8 182.8 signal
12 Tooth Injury 506 152.3 156.7 signal
13 Protein Total Abnormal 150 151.0 152.3 signal
14 Cd4 Lymphocyte Percentage Decreased 5 147.1 147.2 signal
15 Osteonecrosis 3,385 132.5 162.9 signal
16 Product Use In Unapproved Therapeutic Environment 73 112.3 112.7 signal
17 Degenerative Bone Disease 38 109.3 109.5 signal
18 Renal Injury 2,488 105.2 121.9 signal
19 Anhedonia 2,154 103.1 116.9 signal
20 Hiv Viraemia 16 96.6 96.7 signal
21 Viral Load Increased 281 90.3 91.7 signal
22 Cd4 Lymphocytes Abnormal 15 89.2 89.3 signal
23 Hiv-associated Neurocognitive Disorder 8 89.1 89.2 signal
24 Osteoporosis 2,781 84.3 99.5 signal
25 Monkeypox 17 83.0 83.1 signal
26 Blood Hiv Rna Increased 118 82.0 82.5 signal
27 Secondary Syphilis 6 74.0 74.1 signal
28 Fear-related Avoidance Of Activities 9 72.2 72.3 signal
29 Teeth Brittle 60 70.2 70.4 signal
30 Vitamin D Deficiency 504 63.4 65.2 signal
31 Genotype Drug Resistance Test Positive 51 60.1 60.3 signal
32 Glomerular Filtration Rate Abnormal 68 59.1 59.3 signal
33 Chronic Kidney Disease 3,644 58.1 72.6 signal
34 Osteomalacia 74 58.0 58.2 signal
35 Viral Load 8 56.0 56.0 signal
36 Fanconi Syndrome Acquired 79 55.0 55.2 signal
37 Economic Problem 694 54.9 57.0 signal
38 Pelvic Kidney 5 53.1 53.1 signal
39 Eosinophilic Pustular Folliculitis 4 51.6 51.6 signal
40 Cd4 Lymphocytes Decreased 88 49.4 49.7 signal
41 Drug Resistance Mutation 7 48.1 48.1 signal
42 Nephropathy 358 46.1 47.1 signal
43 Cd4 Lymphocytes Increased 9 46.1 46.1 signal
44 Protein Total Increased 91 41.3 41.5 signal
45 Viraemia 45 38.9 39.0 signal
46 Encephalocele 8 38.1 38.1 signal
47 Virologic Failure 168 37.4 37.7 signal
48 Cryptococcal Meningoencephalitis 4 36.7 36.7 signal
49 Glomerular Filtration Rate Increased 24 35.4 35.4 signal
50 Avulsion Fracture 8 33.3 33.3 signal
51 Acute Hepatitis B 9 32.1 32.1 signal
52 Kidney Rupture 5 31.9 31.9 signal
53 Immune Reconstitution Inflammatory Syndrome 130 31.0 31.2 signal
54 Hand Fracture 178 30.0 30.3 signal
55 Syphilis 18 29.5 29.5 signal
56 Oesophageal Squamous Cell Carcinoma 6 29.2 29.2 signal
57 Fracture 459 28.9 29.6 signal
58 Disseminated Mycobacterium Avium Complex Infection 5 28.0 28.0 signal
59 Renal Tubular Dysfunction 13 27.7 27.7 signal
60 Renal Failure 3,037 27.0 32.3 signal
61 Gonorrhoea 6 26.4 26.4 signal
62 Fat Redistribution 5 25.4 25.4 signal
63 T-lymphocyte Count Decreased 14 24.3 24.4 signal
64 Emotional Distress 2,435 23.8 27.3 signal
65 Cd4/cd8 Ratio Decreased 4 23.3 23.3 signal
66 Gastrointestinal Tube Insertion 49 23.3 23.3 signal
67 Adamts13 Activity Decreased 5 23.2 23.2 signal
68 Acquired Immunodeficiency Syndrome 10 23.0 23.1 signal
69 Tooth Fracture 214 23.0 23.3 signal
70 Chronic Kidney Disease-mineral And Bone Disorder 20 22.0 22.0 signal
71 Jaw Fracture 40 21.9 21.9 signal
72 Sitting Disability 11 21.8 21.9 signal
73 Foot Fracture 344 21.4 21.8 signal
74 Osteoporotic Fracture 34 20.9 20.9 signal
75 Fibula Fracture 51 20.8 20.9 signal
76 Forearm Fracture 12 20.4 20.4 signal
77 Hepatitis B Surface Antibody Positive 5 20.1 20.1 signal
78 Viral Mutation Identified 60 19.1 19.2 signal
79 Shoulder Fracture 24 18.2 18.2 signal
80 Hiv Infection 46 18.0 18.0 signal
81 Superinfection Bacterial 12 17.9 17.9 signal
82 Tibia Fracture 71 17.8 17.9 signal
83 Hiv Test Positive 10 17.7 17.7 signal
84 Ankle Fracture 229 17.4 17.6 signal
85 Vertebral Foraminal Stenosis 12 17.1 17.1 signal
86 Wrist Fracture 161 15.8 16.0 signal
87 Hepatitis B Dna Increased 9 15.7 15.7 signal
88 Hepatitis B Core Antibody Positive 5 15.7 15.7 signal
89 Blood Beta-d-glucan Increased 4 15.4 15.4 signal
90 Hemiparaesthesia 5 15.3 15.3 signal
91 Radius Fracture 31 15.1 15.1 signal
92 Haemangioma Congenital 6 14.8 14.8 signal
93 Ulna Fracture 12 14.2 14.2 signal
94 Blood Creatinine Increased 786 14.1 14.7 signal
95 Comminuted Fracture 4 14.1 14.1 signal
96 Clavicle Fracture 46 14.1 14.1 signal
97 Cerebral Toxoplasmosis 11 13.8 13.8 signal
98 Scapula Fracture 6 13.7 13.7 signal
99 Intervertebral Disc Degeneration 106 13.4 13.5 signal
100 Pathogen Resistance 102 13.2 13.2 signal
101 Fractured Coccyx 14 13.1 13.1 signal
102 Gastrostomy 17 13.0 13.0 signal
103 Chlamydial Infection 8 12.4 12.4 signal
104 Bone Disorder 192 12.3 12.4 signal
105 Product Confusion 8 12.1 12.1 signal
106 End Stage Renal Disease 179 11.4 11.5 signal
107 Renal Impairment 810 11.4 11.9 signal
108 Renal Tubular Injury 11 11.2 11.2 signal
109 Albuminuria 5 11.0 11.0 signal
110 Pneumomediastinum 16 10.5 10.5 signal
111 Fat Tissue Increased 13 10.5 10.5 signal
112 Rib Fracture 182 10.4 10.5 signal
113 Glomerular Filtration Rate Decreased 107 10.4 10.4 signal
114 Blood Creatine Phosphokinase Abnormal 4 10.2 10.2 signal
115 Intervertebral Disc Space Narrowing 7 10.2 10.2 signal
116 Blood Creatine Increased 38 10.0 10.1 signal
117 Osteogenesis Imperfecta 5 10.0 10.0 signal
118 Spinal Osteoarthritis 75 10.0 10.0 signal
119 Cervical Radiculopathy 6 9.8 9.8 signal
120 Proteinuria 157 9.8 9.8 signal
121 Pathological Fracture 42 9.7 9.7 signal
122 Facial Bones Fracture 30 9.6 9.6 signal
123 Anxiety 2,282 9.4 10.6 signal
124 Atypical Mycobacterial Infection 11 9.3 9.3 signal
125 Humerus Fracture 38 9.2 9.2 signal
126 Endotracheal Intubation 21 8.8 8.8 signal
127 Lipodystrophy Acquired 16 8.8 8.8 signal
128 Glycosuria 10 8.7 8.7 signal
129 Patella Fracture 17 8.5 8.6 signal
130 Foetal Heart Rate Deceleration Abnormality 5 8.3 8.3 signal
131 Enteral Nutrition 4 8.3 8.3 signal
132 Counterfeit Product Administered 9 8.3 8.3 signal
133 Spinal Compression Fracture 59 8.2 8.3 signal
134 Hepatitis B Reactivation 22 8.1 8.1 signal
135 Spinal Stenosis 28 8.0 8.0 signal
136 Protein Urine Present 34 8.0 8.0 signal
137 Mycobacterium Avium Complex Infection 18 7.9 7.9 signal
138 Upper Limb Fracture 134 7.8 7.9 signal
139 Exposure To Communicable Disease 5 7.8 7.8 signal
140 Persecutory Delusion 16 7.6 7.6 signal
141 Blood Creatinine Abnormal 22 7.5 7.5 signal
142 Trisomy 21 8 7.4 7.4 signal
143 Partner Stress 6 7.3 7.3 signal
144 Craniofacial Fracture 5 7.2 7.2 signal
145 Lumbar Vertebral Fracture 28 7.2 7.2 signal
146 Anal Cancer 6 7.2 7.2 signal
147 Tooth Erosion 7 7.2 7.2 signal
148 Multiple-drug Resistance 19 7.2 7.2 signal
149 Lower Limb Fracture 117 7.2 7.2 signal
150 Hip Arthroplasty 93 7.2 7.2 signal
151 Osteoarthritis 253 7.0 7.1 signal
152 Product Counterfeit 10 7.0 7.0 signal
153 Bone Deformity 4 7.0 7.0 signal
154 Abdominal Lymphadenopathy 5 6.8 6.8 signal
155 Pharyngeal Inflammation 7 6.8 6.8 signal
156 Meningitis Cryptococcal 10 6.8 6.8 signal
157 Cervical Spinal Stenosis 10 6.8 6.8 signal
158 Cytomegalovirus Chorioretinitis 11 6.7 6.7 signal
159 Renal Cyst 45 6.6 6.6 signal
160 Dental Caries 62 6.6 6.6 signal
161 Oropharyngeal Candidiasis 5 6.5 6.5 signal
162 Toxoplasmosis 6 6.5 6.5 signal
163 Cervical Vertebral Fracture 19 6.5 6.5 signal
164 Lipids Increased 11 6.4 6.4 signal
165 Seborrhoeic Dermatitis 9 6.4 6.4 signal
166 Acute Kidney Injury 825 6.3 6.6 signal
167 Decreased Activity 58 6.3 6.3 signal
168 Dyslipidaemia 27 6.2 6.2 signal
169 Suspected Counterfeit Product 20 5.9 5.9 signal
170 Compression Fracture 26 5.8 5.8 signal
171 Hepatitis B 30 5.8 5.8 signal
172 Polyhydramnios 5 5.7 5.7 signal
173 Sternal Fracture 6 5.7 5.7 signal
174 Waist Circumference Increased 5 5.6 5.6 signal
175 Product Dispensing Error 104 5.6 5.6 signal
176 Spinal Fracture 94 5.5 5.5 signal
177 Abscess Drainage 4 5.4 5.4 signal
178 Spondylolisthesis 8 5.4 5.4 signal
179 Exercise Tolerance Decreased 26 5.3 5.3 signal
180 Hip Fracture 145 5.3 5.3 signal
181 Anogenital Warts 4 5.2 5.2 signal
182 Lumbar Spinal Stenosis 13 5.2 5.2 signal
183 Renal Mass 9 5.1 5.1 signal
184 Osteochondrosis 5 5.0 5.0 signal
185 Bone Cyst 4 5.0 5.0 signal
186 Quality Of Life Decreased 57 5.0 5.0 signal
187 Pain 2,546 4.8 5.5 signal
188 Facet Joint Syndrome 13 4.8 4.8 signal
189 Product Packaging Difficult To Open 10 4.7 4.7 signal
190 Fractured Sacrum 5 4.7 4.7 signal
191 Renal Atrophy 5 4.7 4.7 signal
192 Intervertebral Disc Disorder 17 4.6 4.6 signal
193 Drug Resistance 98 4.5 4.5 signal
194 Shoulder Arthroplasty 10 4.4 4.4 signal
195 Renal Pain 39 4.3 4.3 signal
196 Stress Fracture 20 4.3 4.3 signal
197 Renal Tubular Acidosis 8 4.3 4.3 signal
198 Agoraphobia 5 4.3 4.3 signal
199 Vaccination Failure 6 4.2 4.2 signal
200 Halo Vision 4 4.1 4.1 signal
201 Tooth Extraction 43 4.0 4.0 signal
202 Renal Tubular Necrosis 33 3.9 3.9 signal
203 Femoral Neck Fracture 17 3.9 3.9 signal
204 Loss Of Personal Independence In Daily Activities 156 3.8 3.9 signal
205 Hyperaesthesia Teeth 4 3.8 3.8 signal
206 Drug Screen False Positive 9 3.8 3.8 signal
207 Histoplasmosis Disseminated 5 3.7 3.7 signal
208 Hyperparathyroidism Secondary 8 3.7 3.7 signal
209 Product Package Associated Injury 7 3.7 3.7 signal
210 Tinea Pedis 5 3.7 3.7 signal
211 Intercepted Product Dispensing Error 5 3.6 3.6 signal
212 Iga Nephropathy 5 3.6 3.6 signal
213 Glucose Tolerance Impaired 18 3.6 3.6 signal
214 Thoracic Vertebral Fracture 9 3.6 3.6 signal
215 Renal Transplant 11 3.6 3.6 signal
216 Intentional Dose Omission 83 3.5 3.6 signal
217 Hepatic Cytolysis 37 3.5 3.5 signal
218 Creatinine Renal Clearance Decreased 12 3.5 3.5 signal
219 Dysstasia 87 3.5 3.5 signal
220 Infusion Site Discharge 5 3.4 3.4 signal
221 Hyperparathyroidism 6 3.4 3.4 signal
222 Blood Creatinine Decreased 9 3.4 3.4 signal
223 Fanconi Syndrome 4 3.3 3.3 signal
224 Nephrolithiasis 127 3.2 3.3 signal
225 Product Temperature Excursion Issue 13 3.2 3.2 signal
226 Pneumocystis Jirovecii Pneumonia 27 3.1 3.2 signal
227 Opportunistic Infection 5 3.1 3.1 signal
228 Spinal Column Injury 6 3.1 3.1 signal
229 Post-traumatic Stress Disorder 18 3.1 3.1 signal
230 Epicondylitis 4 3.1 3.1 no signal
231 Mechanical Ventilation 5 3.0 3.0 signal
232 Lichen Planus 6 3.0 3.0 signal
233 Poisoning Deliberate 24 3.0 3.0 signal
234 Gene Mutation 5 2.9 2.9 signal
235 Femur Fracture 78 2.9 2.9 signal
236 Blood Lactic Acid Increased 13 2.9 2.9 signal
237 Loose Tooth 8 2.9 2.9 signal
238 Product Storage Error 207 2.8 2.8 signal
239 Sleep Terror 10 2.8 2.8 signal
240 Abnormal Dreams 66 2.8 2.8 signal
241 Disseminated Tuberculosis 6 2.7 2.7 signal
242 Renal Neoplasm 5 2.7 2.7 no signal
243 Treatment Noncompliance 127 2.7 2.7 signal
244 Extremity Necrosis 4 2.7 2.7 no signal
245 Depressive Symptom 8 2.7 2.7 signal
246 Radiculopathy 6 2.7 2.7 signal
247 Alcohol Poisoning 6 2.6 2.6 signal
248 Product Dispensing Issue 8 2.6 2.6 signal
249 Pancreatitis Necrotising 5 2.6 2.6 no signal
250 Exostosis 20 2.6 2.6 signal
251 Pelvic Fracture 17 2.6 2.6 signal
252 Lymphoedema 15 2.5 2.5 signal
253 Weight Increased 481 2.5 2.6 signal
254 Haemangioma 5 2.5 2.5 no signal
255 Pancreatitis Chronic 5 2.5 2.5 no signal
256 Pulmonary Tuberculosis 9 2.5 2.5 signal
257 Weight Abnormal 5 2.4 2.4 no signal
258 Mixed Liver Injury 6 2.4 2.4 no signal
259 Oesophageal Candidiasis 8 2.4 2.4 signal
260 Emergency Care 6 2.4 2.4 no signal
261 Renal Disorder 94 2.3 2.4 signal
262 Miosis 16 2.3 2.3 signal
263 Foetal Growth Restriction 12 2.3 2.3 signal
264 Nephropathy Toxic 22 2.3 2.3 signal
265 Product Use Complaint 30 2.3 2.3 signal
266 Lipoma 5 2.3 2.3 no signal
267 Skin Abrasion 9 2.2 2.2 signal
268 Bipolar Disorder 21 2.2 2.2 signal
269 Circumstance Or Information Capable Of Leading To Medication Error 64 2.2 2.2 signal
270 Maternal Exposure During Pregnancy 167 2.2 2.2 signal
271 Bone Pain 111 2.2 2.2 signal
272 Cholestatic Liver Injury 4 2.2 2.2 no signal
273 Weight Bearing Difficulty 5 2.2 2.2 no signal
274 Muscle Atrophy 23 2.1 2.1 signal
275 Nephritis 6 2.1 2.1 no signal
276 Accident At Work 4 2.1 2.1 no signal
277 Haemophagocytic Lymphohistiocytosis 13 2.1 2.1 signal
278 Calcinosis 4 2.1 2.1 no signal
279 Plantar Fasciitis 6 2.1 2.1 no signal
280 Skin Odour Abnormal 7 2.1 2.1 no signal
281 Lung Consolidation 5 2.1 2.1 no signal
282 Depression 406 2.1 2.1 signal
283 Renal Tubular Disorder 5 2.1 2.1 no signal
284 Nightmare 60 2.0 2.0 signal
285 Hypertriglyceridaemia 10 2.0 2.0 no signal
286 Toxic Skin Eruption 17 2.0 2.0 no signal
287 Pollakiuria 69 1.9 1.9 no signal
288 Tooth Disorder 37 1.9 1.9 no signal
289 Tuberculosis 21 1.9 1.9 no signal
290 Scoliosis 10 1.9 1.9 no signal
291 Necrosis 9 1.9 1.9 no signal
292 Nephrotic Syndrome 11 1.9 1.9 no signal
293 Cytomegalovirus Viraemia 7 1.9 1.9 no signal
294 Product Colour Issue 8 1.8 1.8 no signal
295 Hepatitis C 19 1.8 1.8 no signal
296 Hepatosplenomegaly 4 1.8 1.8 no signal
297 Lymphoma 24 1.8 1.8 no signal
298 Liver Function Test Increased 33 1.8 1.8 no signal
299 Near Death Experience 5 1.8 1.8 no signal
300 Product Dose Omission In Error 41 1.8 1.8 no signal
301 Hyperlactacidaemia 4 1.8 1.8 no signal
302 Blood Cholesterol Abnormal 7 1.8 1.8 no signal
303 Product Packaging Issue 14 1.8 1.8 no signal
304 Intervertebral Disc Protrusion 33 1.8 1.8 no signal
305 Nephrogenic Anaemia 7 1.7 1.7 no signal
306 Impaired Work Ability 32 1.7 1.7 no signal
307 Bradypnoea 4 1.7 1.7 no signal
308 Mobility Decreased 106 1.7 1.7 no signal
309 Pre-eclampsia 7 1.7 1.7 no signal
310 Hydronephrosis 11 1.7 1.7 no signal
311 Hyperbilirubinaemia 15 1.7 1.7 no signal
312 Loss Of Libido 13 1.7 1.7 no signal
313 Erythema Nodosum 5 1.7 1.7 no signal
314 Muscle Fatigue 6 1.7 1.7 no signal
315 Hyperlipidaemia 17 1.7 1.7 no signal
316 Thrombotic Thrombocytopenic Purpura 5 1.6 1.6 no signal
317 Haemodialysis 12 1.6 1.6 no signal
318 Throat Cancer 6 1.6 1.6 no signal
319 Cytomegalovirus Infection Reactivation 6 1.6 1.6 no signal
320 Vitamin D Decreased 12 1.6 1.6 no signal
321 Hepatic Steatosis 26 1.6 1.6 no signal
322 Liver Transplant 5 1.6 1.6 no signal
323 Liver Injury 33 1.6 1.6 no signal
324 Wrong Product Administered 9 1.6 1.6 no signal
325 Blood Triglycerides Increased 24 1.6 1.6 no signal
326 Benign Prostatic Hyperplasia 7 1.6 1.6 no signal
327 Progressive Multifocal Leukoencephalopathy 11 1.6 1.6 no signal
328 Joint Dislocation 14 1.5 1.5 no signal
329 Kidney Infection 26 1.5 1.5 no signal
330 Prescription Drug Used Without A Prescription 8 1.5 1.5 no signal
331 Disease Complication 6 1.5 1.5 no signal
332 Meniscus Injury 8 1.5 1.5 no signal
333 Colitis Microscopic 6 1.5 1.5 no signal
334 Gestational Diabetes 6 1.5 1.5 no signal
335 Family Stress 4 1.5 1.5 no signal
336 Polydipsia 5 1.5 1.5 no signal
337 Hyperphagia 5 1.5 1.5 no signal
338 Obesity 20 1.5 1.5 no signal
339 Skin Lesion 34 1.5 1.5 no signal
340 Dysuria 46 1.5 1.5 no signal
341 Spinal Fusion Surgery 5 1.4 1.4 no signal
342 Erectile Dysfunction 32 1.4 1.4 no signal
343 Chromaturia 28 1.4 1.4 no signal
344 Haemarthrosis 11 1.4 1.4 no signal
345 Gait Disturbance 234 1.4 1.4 no signal
346 Psychiatric Symptom 9 1.4 1.4 no signal
347 Peripheral Sensory Neuropathy 7 1.4 1.4 no signal
348 Spinal Pain 14 1.4 1.4 no signal
349 Febrile Bone Marrow Aplasia 5 1.4 1.4 no signal
350 Anxiety Disorder 4 1.4 1.4 no signal
351 Odynophagia 7 1.4 1.4 no signal
352 Lipase Increased 9 1.4 1.4 no signal
353 Helicobacter Infection 12 1.4 1.4 no signal
354 Abscess Limb 5 1.4 1.4 no signal
355 Hepatic Fibrosis 4 1.4 1.4 no signal
356 Rotator Cuff Syndrome 15 1.4 1.4 no signal
357 Peripheral Coldness 16 1.4 1.4 no signal
358 Spinal Disorder 11 1.3 1.3 no signal
359 Hepatic Failure 35 1.3 1.3 no signal
360 Ocular Icterus 5 1.3 1.3 no signal
361 Immunodeficiency 17 1.3 1.3 no signal
362 Lactic Acidosis 37 1.3 1.3 no signal
363 Transaminases Increased 25 1.3 1.3 no signal
364 Physical Disability 5 1.3 1.3 no signal
365 Anorectal Discomfort 6 1.3 1.3 no signal
366 Urine Abnormality 5 1.3 1.3 no signal
367 Haemoglobin Increased 5 1.3 1.3 no signal
368 Polyuria 9 1.3 1.3 no signal
369 Pancreatitis 58 1.3 1.3 no signal
370 Amylase Increased 4 1.3 1.3 no signal
371 Renal Function Test Abnormal 5 1.3 1.3 no signal
372 Live Birth 9 1.3 1.3 no signal
373 Abortion Induced 10 1.2 1.2 no signal
374 Hypercholesterolaemia 10 1.2 1.2 no signal
375 Product Label Issue 7 1.2 1.2 no signal
376 Low Density Lipoprotein Increased 8 1.2 1.2 no signal
377 Therapy Change 10 1.2 1.2 no signal
378 Guillain-barre Syndrome 5 1.2 1.2 no signal
379 Mental Disorder 45 1.2 1.2 no signal
380 Product Preparation Issue 6 1.2 1.2 no signal
381 Dysphagia 97 1.2 1.2 no signal
382 Gastrointestinal Sounds Abnormal 5 1.2 1.2 no signal
383 Decreased Interest 6 1.2 1.2 no signal
384 Labelled Drug-drug Interaction Medication Error 9 1.2 1.2 no signal
385 Type 1 Diabetes Mellitus 6 1.2 1.2 no signal
386 Nocturia 12 1.2 1.2 no signal
387 Blood Calcium Decreased 11 1.1 1.1 no signal
388 Malabsorption 5 1.1 1.1 no signal
389 Blood Creatine Phosphokinase Increased 28 1.1 1.1 no signal
390 Major Depression 7 1.1 1.1 no signal
391 Squamous Cell Carcinoma 9 1.1 1.1 no signal
392 Sensation Of Foreign Body 8 1.1 1.1 no signal
393 Escherichia Urinary Tract Infection 4 1.1 1.1 no signal
394 Pancreatitis Acute 21 1.1 1.1 no signal
395 Autoimmune Disorder 9 1.1 1.1 no signal
396 Pharyngeal Swelling 9 1.1 1.1 no signal
397 Osteomyelitis 17 1.1 1.1 no signal
398 Hepatic Pain 4 1.1 1.1 no signal
399 Haemodynamic Instability 7 1.1 1.1 no signal
400 Pancytopenia 52 1.1 1.1 no signal
401 Nonspecific Reaction 5 1.1 1.1 no signal
402 Aspergillus Infection 6 1.1 1.1 no signal
403 Product Administration Interrupted 7 1.1 1.1 no signal
404 Dysphemia 4 1.1 1.1 no signal
405 Foetal Exposure During Pregnancy 74 1.1 1.1 no signal
406 Recalled Product Administered 8 1.1 1.1 no signal
407 Tubulointerstitial Nephritis 17 1.1 1.1 no signal
408 Product Distribution Issue 8 1.1 1.1 no signal
409 Arthritis 71 1.0 1.0 no signal
410 Sleep Disorder 63 1.0 1.0 no signal
411 Anal Incontinence 8 1.0 1.0 no signal
412 Streptococcal Infection 5 1.0 1.0 no signal
413 Gout 16 1.0 1.0 no signal
414 Cholestasis 17 1.0 1.0 no signal
415 Joint Injury 19 1.0 1.0 no signal
416 Fear 24 1.0 1.0 no signal
417 Product Dose Omission 58 1.0 1.0 no signal
418 Musculoskeletal Discomfort 15 1.0 1.0 no signal
419 Blood Testosterone Decreased 6 1.0 1.0 no signal
420 Arthritis Infective 4 1.0 1.0 no signal
421 Infusion Site Pain 11 1.0 1.0 no signal
422 Rales 5 1.0 1.0 no signal
423 Product Dose Omission Issue 245 1.0 1.0 no signal
424 Product Label Confusion 5 1.0 1.0 no signal
425 Erythema Multiforme 8 1.0 1.0 no signal
426 Haematuria 29 1.0 1.0 no signal
427 Infusion Site Erythema 7 1.0 1.0 no signal
428 Eating Disorder 18 1.0 1.0 no signal
429 Back Pain 195 1.0 1.0 no signal
430 Acute Respiratory Failure 16 1.0 1.0 no signal
431 Paralysis 12 1.0 1.0 no signal
432 Glycosylated Haemoglobin Increased 21 1.0 1.0 no signal
433 Hypervolaemia 4 1.0 1.0 no signal
434 Incorrect Route Of Product Administration 14 1.0 1.0 no signal
435 Body Height Decreased 9 1.0 1.0 no signal
436 Bursitis 10 1.0 1.0 no signal
437 Facial Paralysis 7 1.0 1.0 no signal
438 Multiple Organ Dysfunction Syndrome 23 1.0 1.0 no signal
439 Knee Arthroplasty 17 0.9 0.9 no signal
440 Laboratory Test Abnormal 24 0.9 0.9 no signal
441 Pyelonephritis 7 0.9 0.9 no signal
442 Liver Disorder 36 0.9 0.9 no signal
443 Infusion Site Swelling 5 0.9 0.9 no signal
444 Ligament Sprain 8 0.9 0.9 no signal
445 Acute Hepatic Failure 11 0.9 0.9 no signal
446 Hepatic Cirrhosis 15 0.9 0.9 no signal
447 Product Administration Error 16 0.9 0.9 no signal
448 Exposure During Pregnancy 49 0.9 0.9 no signal
449 Blood Urine Present 15 0.9 0.9 no signal
450 Product Prescribing Issue 16 0.9 0.9 no signal
451 Musculoskeletal Disorder 15 0.9 0.9 no signal
452 Oropharyngeal Discomfort 7 0.9 0.9 no signal
453 Pericardial Effusion 18 0.9 0.9 no signal
454 Myositis 7 0.9 0.9 no signal
455 Proctalgia 5 0.9 0.9 no signal
456 Toothache 14 0.9 0.9 no signal
457 Abortion Spontaneous 31 0.9 0.9 no signal
458 Drug Interaction 122 0.9 0.9 no signal
459 Appetite Disorder 5 0.9 0.9 no signal
460 Affective Disorder 6 0.9 0.9 no signal
461 Insomnia 203 0.9 0.9 no signal
462 Apathy 11 0.9 0.9 no signal
463 Rash Papular 17 0.9 0.9 no signal
464 Sciatica 12 0.9 0.9 no signal
465 Brain Fog 11 0.9 0.9 no signal
466 Product Physical Issue 15 0.9 0.9 no signal
467 Food Poisoning 4 0.9 0.9 no signal
468 Paranoia 13 0.9 0.9 no signal
469 Coronavirus Infection 5 0.9 0.9 no signal
470 Poor Quality Sleep 16 0.9 0.9 no signal
471 Blood Bilirubin Increased 20 0.9 0.9 no signal
472 Drug Eruption 13 0.9 0.9 no signal
473 Hiccups 6 0.9 0.9 no signal
474 Faecaloma 4 0.9 0.9 no signal
475 Hallucination 55 0.9 0.9 no signal
476 Diabetes Mellitus 56 0.9 0.9 no signal
477 Hepatic Function Abnormal 27 0.8 0.8 no signal
478 Suicide Attempt 44 0.8 0.8 no signal
479 Rash Maculo-papular 16 0.8 0.8 no signal
480 Malnutrition 8 0.8 0.8 no signal
481 Neuropathy Peripheral 68 0.8 0.8 no signal
482 Candida Infection 12 0.8 0.8 no signal
483 Panic Attack 26 0.8 0.8 no signal
484 Product Container Issue 6 0.8 0.8 no signal
485 Product Supply Issue 5 0.8 0.8 no signal
486 Dermatitis Contact 8 0.8 0.8 no signal
487 Arthralgia 291 0.8 0.8 no signal
488 Rhabdomyolysis 29 0.8 0.8 no signal
489 Abdominal Distension 72 0.8 0.8 no signal
490 Oral Candidiasis 9 0.8 0.8 no signal
491 Mood Swings 22 0.8 0.8 no signal
492 Hyperventilation 4 0.8 0.8 no signal
493 Hospitalisation 105 0.8 0.8 no signal
494 Hyperglycaemia 25 0.8 0.8 no signal
495 Hyperkalaemia 24 0.8 0.8 no signal
496 Premature Delivery 11 0.8 0.8 no signal
497 Eosinophilia 12 0.8 0.8 no signal
498 Initial Insomnia 7 0.8 0.8 no signal
499 Bradykinesia 4 0.8 0.8 no signal
500 Hypophosphataemia 5 0.8 0.8 no signal
501 Cytopenia 8 0.8 0.8 no signal
502 Cytomegalovirus Infection 11 0.8 0.8 no signal
503 Bowel Movement Irregularity 5 0.8 0.8 no signal
504 Acidosis 5 0.8 0.8 no signal
505 Night Sweats 21 0.8 0.8 no signal
506 Agranulocytosis 12 0.8 0.8 no signal
507 Back Injury 7 0.8 0.8 no signal
508 Libido Decreased 8 0.8 0.8 no signal
509 Atrioventricular Block 5 0.8 0.8 no signal
510 Neoplasm Malignant 43 0.8 0.7 no signal
511 Ocular Discomfort 7 0.7 0.7 no signal
512 Cyst 8 0.7 0.7 no signal
513 Product Packaging Quantity Issue 7 0.7 0.7 no signal
514 Gastrointestinal Pain 7 0.7 0.7 no signal
515 Gynaecomastia 20 0.7 0.7 no signal
516 Hepatocellular Injury 9 0.7 0.7 no signal
517 Suicidal Ideation 58 0.7 0.7 no signal
518 Myalgia 107 0.7 0.7 no signal
519 Low Birth Weight Baby 5 0.7 0.7 no signal
520 Hypersomnia 18 0.7 0.7 no signal
521 Impaired Quality Of Life 9 0.7 0.7 no signal
522 Hepatitis 16 0.7 0.7 no signal
523 Treatment Failure 51 0.7 0.7 no signal
524 Alanine Aminotransferase Increased 38 0.7 0.7 no signal
525 Hepatitis Acute 4 0.7 0.7 no signal
526 Hypertension 131 0.7 0.7 no signal
527 Hypokalaemia 28 0.7 0.7 no signal
528 Abnormal Faeces 5 0.7 0.7 no signal
529 Hospice Care 6 0.7 0.7 no signal
530 Neoplasm 7 0.7 0.7 no signal
531 Insurance Issue 9 0.7 0.7 no signal
532 Blood Alkaline Phosphatase Increased 15 0.7 0.7 no signal
533 Coagulopathy 10 0.7 0.7 no signal
534 Product Use Issue 112 0.7 0.7 no signal
535 Splenomegaly 7 0.7 0.7 no signal
536 Bacteraemia 7 0.7 0.7 no signal
537 Motor Dysfunction 6 0.7 0.7 no signal
538 Jaundice 16 0.7 0.7 no signal
539 Bacterial Infection 11 0.7 0.7 no signal
540 Hypophagia 15 0.7 0.7 no signal
541 Limb Injury 16 0.7 0.7 no signal
542 Hepatic Enzyme Increased 40 0.7 0.7 no signal
543 Accident 7 0.7 0.7 no signal
544 Temperature Intolerance 6 0.7 0.7 no signal
545 Tooth Abscess 6 0.7 0.7 no signal
546 Hypertransaminasaemia 4 0.7 0.7 no signal
547 Product Communication Issue 5 0.7 0.7 no signal
548 Drug Level Decreased 6 0.7 0.7 no signal
549 Increased Appetite 11 0.7 0.7 no signal
550 Folliculitis 6 0.7 0.7 no signal
551 Encephalitis 4 0.7 0.7 no signal
552 Therapy Interrupted 40 0.7 0.7 no signal
553 Spinal Operation 7 0.7 0.7 no signal
554 Asthenia 217 0.7 0.7 no signal
555 Gait Inability 19 0.7 0.7 no signal
556 Formication 4 0.7 0.7 no signal
557 Extrasystoles 4 0.7 0.7 no signal
558 Metabolic Acidosis 18 0.7 0.7 no signal
559 Pneumothorax 9 0.7 0.7 no signal
560 Rash 246 0.7 0.7 no signal
561 Groin Pain 5 0.7 0.7 no signal
562 Seasonal Allergy 8 0.7 0.7 no signal
563 Epilepsy 17 0.6 0.6 no signal
564 Stress 40 0.6 0.6 no signal
565 Anaemia 106 0.6 0.6 no signal
566 Feeding Disorder 11 0.6 0.6 no signal
567 Drug-induced Liver Injury 17 0.6 0.6 no signal
568 Generalised Tonic-clonic Seizure 9 0.6 0.6 no signal
569 Therapy Cessation 28 0.6 0.6 no signal
570 Aspartate Aminotransferase Increased 29 0.6 0.6 no signal
571 Brain Neoplasm 5 0.6 0.6 no signal
572 Death 467 0.6 0.6 no signal
573 Nerve Injury 6 0.6 0.6 no signal
574 Feeling Drunk 4 0.6 0.6 no signal
575 Flank Pain 5 0.6 0.6 no signal
576 Type 2 Diabetes Mellitus 18 0.6 0.6 no signal
577 Face Oedema 9 0.6 0.6 no signal
578 Myocarditis 6 0.6 0.6 no signal
579 Micturition Urgency 6 0.6 0.6 no signal
580 Movement Disorder 17 0.6 0.6 no signal
581 Road Traffic Accident 22 0.6 0.6 no signal
582 Diffuse Large B-cell Lymphoma 4 0.6 0.6 no signal
583 Hepatocellular Carcinoma 4 0.6 0.6 no signal
584 Internal Haemorrhage 6 0.6 0.6 no signal
585 Fatigue 407 0.6 0.6 no signal
586 Joint Range Of Motion Decreased 7 0.6 0.6 no signal
587 Mouth Ulceration 11 0.6 0.6 no signal
588 Sleep Apnoea Syndrome 10 0.6 0.6 no signal
589 Aortic Aneurysm 4 0.6 0.6 no signal
590 Respiratory Failure 38 0.6 0.6 no signal
591 Gastric Disorder 18 0.6 0.6 no signal
592 Thrombotic Microangiopathy 5 0.6 0.6 no signal
593 Blood Cholesterol Increased 24 0.6 0.6 no signal
594 General Physical Health Deterioration 59 0.6 0.6 no signal
595 Nervous System Disorder 16 0.6 0.6 no signal
596 Blood Iron Decreased 6 0.6 0.6 no signal
597 Drug Screen Positive 4 0.6 0.6 no signal
598 Covid-19 Pneumonia 6 0.6 0.6 no signal
599 Rash Pruritic 27 0.6 0.6 no signal
600 Neck Pain 28 0.6 0.6 no signal
601 Atrial Flutter 4 0.6 0.6 no signal
602 Carpal Tunnel Syndrome 7 0.6 0.6 no signal
603 Premature Baby 15 0.6 0.6 no signal
604 Sensory Disturbance 8 0.6 0.6 no signal
605 Disseminated Intravascular Coagulation 7 0.6 0.6 no signal
606 Stevens-johnson Syndrome 11 0.6 0.6 no signal
607 Schizophrenia 6 0.6 0.6 no signal
608 Hypothermia 5 0.6 0.6 no signal
609 Cerebral Infarction 12 0.6 0.6 no signal
610 Escherichia Infection 4 0.6 0.6 no signal
611 Ear Discomfort 5 0.6 0.6 no signal
612 Hyperthyroidism 7 0.6 0.6 no signal
613 Hyperaesthesia 4 0.6 0.6 no signal
614 Shock 11 0.6 0.6 no signal
615 Abnormal Weight Gain 6 0.6 0.6 no signal
616 Disturbance In Attention 26 0.6 0.6 no signal
617 Abdominal Discomfort 80 0.6 0.6 no signal
618 Haemorrhage 50 0.6 0.6 no signal
619 Intentional Product Use Issue 42 0.6 0.6 no signal
620 Atrial Septal Defect 4 0.6 0.6 no signal
621 Blood Urea Increased 8 0.6 0.6 no signal
622 Depressed Mood 25 0.6 0.6 no signal
623 Eructation 9 0.6 0.6 no signal
624 Pulmonary Mass 7 0.5 0.5 no signal
625 Colon Cancer 7 0.5 0.5 no signal
626 Illness 47 0.5 0.5 no signal
627 Mental Status Changes 13 0.5 0.5 no signal
628 Sudden Death 5 0.5 0.5 no signal
629 Accidental Overdose 17 0.5 0.5 no signal
630 Unevaluable Event 35 0.5 0.5 no signal
631 Ill-defined Disorder 28 0.5 0.5 no signal
632 Rash Macular 16 0.5 0.5 no signal
633 Flatulence 26 0.5 0.5 no signal
634 Neutropenia 62 0.5 0.5 no signal
635 Grip Strength Decreased 4 0.5 0.5 no signal
636 Hypoaesthesia 68 0.5 0.5 no signal
637 Musculoskeletal Chest Pain 7 0.5 0.5 no signal
638 Taste Disorder 9 0.5 0.5 no signal
639 Headache 281 0.5 0.5 no signal
640 Skin Infection 5 0.5 0.5 no signal
641 Alopecia 88 0.5 0.5 no signal
642 Head Injury 14 0.5 0.5 no signal
643 Mood Altered 12 0.5 0.5 no signal
644 Muscle Spasms 81 0.5 0.5 no signal
645 Leukopenia 22 0.5 0.5 no signal
646 Psychotic Disorder 13 0.5 0.5 no signal
647 Cholecystectomy 5 0.5 0.5 no signal
648 Hallucination, Auditory 7 0.5 0.5 no signal
649 Akathisia 6 0.5 0.5 no signal
650 Gingival Bleeding 6 0.5 0.5 no signal
651 Central Nervous System Lesion 6 0.5 0.5 no signal
652 Pain In Extremity 128 0.5 0.5 no signal
653 Diarrhoea 278 0.5 0.5 no signal
654 Blood Potassium Increased 7 0.5 0.5 no signal
655 Drug Reaction With Eosinophilia And Systemic Symptoms 11 0.5 0.5 no signal
656 Pulmonary Hypertension 9 0.5 0.5 no signal
657 Middle Insomnia 8 0.5 0.5 no signal
658 Cognitive Disorder 20 0.5 0.5 no signal
659 Vomiting 201 0.5 0.5 no signal
660 Back Disorder 7 0.5 0.5 no signal
661 Thinking Abnormal 8 0.5 0.5 no signal
662 Photosensitivity Reaction 7 0.5 0.5 no signal
663 Skin Fissures 8 0.5 0.5 no signal
664 Nausea 334 0.5 0.5 no signal
665 Staphylococcal Infection 14 0.5 0.5 no signal
666 Dialysis 6 0.5 0.5 no signal
667 Adrenal Insufficiency 5 0.5 0.5 no signal
668 Paraesthesia Oral 6 0.5 0.5 no signal
669 Skin Haemorrhage 6 0.5 0.5 no signal
670 Muscular Weakness 47 0.5 0.5 no signal
671 Neuralgia 10 0.5 0.5 no signal
672 Knee Operation 4 0.5 0.5 no signal
673 Wrong Technique In Product Usage Process 83 0.5 0.5 no signal
674 Injury 29 0.5 0.5 no signal
675 Inability To Afford Medication 4 0.5 0.5 no signal
676 Ileus 5 0.5 0.5 no signal
677 Gamma-glutamyltransferase Increased 9 0.5 0.5 no signal
678 Hypercalcaemia 5 0.5 0.5 no signal
679 Hepatomegaly 4 0.5 0.5 no signal
680 Secretion Discharge 5 0.5 0.5 no signal
681 Tendon Rupture 5 0.5 0.5 no signal
682 Pyrexia 139 0.5 0.5 no signal
683 Productive Cough 19 0.5 0.5 no signal
684 Gastrooesophageal Reflux Disease 32 0.5 0.5 no signal
685 Neoplasm Progression 14 0.5 0.5 no signal
686 Colitis 15 0.5 0.5 no signal
687 Weight Decreased 111 0.5 0.5 no signal
688 Dyspepsia 39 0.5 0.5 no signal
689 Lymphocyte Count Decreased 7 0.5 0.5 no signal
690 Lymphadenopathy 14 0.5 0.5 no signal
691 Arthropathy 22 0.5 0.5 no signal
692 Ischaemic Stroke 7 0.5 0.5 no signal
693 Poor Quality Product Administered 4 0.5 0.5 no signal
694 Muscle Twitching 9 0.5 0.5 no signal
695 Limb Discomfort 12 0.5 0.5 no signal
696 Poor Venous Access 4 0.5 0.5 no signal
697 Scratch 4 0.4 0.4 no signal
698 Irritability 23 0.4 0.4 no signal
699 Joint Stiffness 10 0.4 0.4 no signal
700 Immune System Disorder 5 0.4 0.4 no signal
701 Full Blood Count Abnormal 4 0.4 0.4 no signal
702 Musculoskeletal Pain 20 0.4 0.4 no signal
703 Clostridium Difficile Colitis 4 0.4 0.4 no signal
704 Retching 8 0.4 0.4 no signal
705 Liver Function Test Abnormal 11 0.4 0.4 no signal
706 Irritable Bowel Syndrome 8 0.4 0.4 no signal
707 Abdominal Pain 87 0.4 0.4 no signal
708 Ascites 11 0.4 0.4 no signal
709 Covid-19 66 0.4 0.4 no signal
710 Hunger 5 0.4 0.4 no signal
711 Urinary Incontinence 11 0.4 0.4 no signal
712 Altered State Of Consciousness 8 0.4 0.4 no signal
713 Tinnitus 17 0.4 0.4 no signal
714 Decreased Appetite 85 0.4 0.4 no signal
715 Oesophageal Carcinoma 11 0.4 0.4 no signal
716 Pulmonary Thrombosis 4 0.4 0.4 no signal
717 Seizure 42 0.4 0.4 no signal
718 Cholelithiasis 12 0.4 0.4 no signal
719 Impaired Healing 12 0.4 0.4 no signal
720 Contraindicated Product Administered 11 0.4 0.4 no signal
721 Hyperhidrosis 47 0.4 0.4 no signal
722 Glaucoma 7 0.4 0.4 no signal
723 Skin Disorder 12 0.4 0.4 no signal
724 Dehydration 48 0.4 0.4 no signal
725 Feeling Cold 10 0.4 0.4 no signal
726 Coma 17 0.4 0.4 no signal
727 Blood Test Abnormal 5 0.4 0.4 no signal
728 Drug Effect Less Than Expected 5 0.4 0.4 no signal
729 Musculoskeletal Stiffness 31 0.4 0.4 no signal
730 Hemiparesis 6 0.4 0.4 no signal
731 Migraine 33 0.4 0.4 no signal
732 Angina Pectoris 10 0.4 0.4 no signal
733 Abdominal Pain Upper 71 0.4 0.4 no signal
734 Dysarthria 13 0.4 0.4 no signal
735 Anosmia 5 0.4 0.4 no signal
736 Sexual Dysfunction 4 0.4 0.4 no signal
737 Paraesthesia 54 0.4 0.4 no signal
738 Pruritus 129 0.4 0.4 no signal
739 Head Discomfort 6 0.4 0.4 no signal
740 Gastrointestinal Disorder 30 0.4 0.4 no signal
741 Peripheral Swelling 52 0.4 0.4 no signal
742 Influenza Like Illness 28 0.4 0.4 no signal
743 Product Prescribing Error 8 0.4 0.4 no signal
744 Polyneuropathy 4 0.4 0.4 no signal
745 Dizziness 167 0.4 0.4 no signal
746 Throat Tightness 9 0.4 0.4 no signal
747 Renal Cancer 16 0.4 0.4 no signal
748 Toxic Epidermal Necrolysis 5 0.4 0.4 no signal
749 Off Label Use 286 0.4 0.4 no signal
750 Chest Pain 61 0.4 0.4 no signal
751 Vertigo 20 0.4 0.4 no signal
752 Encephalopathy 8 0.4 0.4 no signal
753 Increased Tendency To Bruise 3 0.4 0.4 no signal
754 Medication Error 18 0.4 0.4 no signal
755 Device Related Infection 5 0.4 0.4 no signal
756 Septic Shock 14 0.4 0.4 no signal
757 Chills 38 0.4 0.4 no signal
758 Emotional Disorder 10 0.4 0.4 no signal
759 Memory Impairment 44 0.4 0.4 no signal
760 Dyspnoea Exertional 12 0.4 0.4 no signal
761 Pruritus Generalised 7 0.4 0.4 no signal
762 Delirium 11 0.4 0.4 no signal
763 Hepatotoxicity 7 0.4 0.4 no signal
764 Product Use In Unapproved Indication 77 0.4 0.4 no signal
765 Gastric Ulcer 6 0.4 0.4 no signal
766 Sepsis 35 0.4 0.4 no signal
767 Lethargy 18 0.4 0.4 no signal
768 Herpes Zoster 18 0.4 0.4 no signal
769 Urinary Tract Infection 53 0.4 0.4 no signal
770 Affect Lability 3 0.4 0.4 no signal
771 Muscle Tightness 5 0.4 0.4 no signal
772 Swelling Face 20 0.4 0.4 no signal
773 Mucosal Inflammation 8 0.4 0.4 no signal
774 Dyspnoea 173 0.4 0.3 no signal
775 Inappropriate Schedule Of Product Administration 54 0.4 0.4 no signal
776 Deafness 8 0.4 0.4 no signal
777 Hot Flush 23 0.4 0.4 no signal
778 Thrombocytopenia 34 0.4 0.4 no signal
779 Inflammatory Bowel Disease 3 0.4 0.4 no signal
780 Mania 5 0.4 0.4 no signal
781 Chest Discomfort 31 0.4 0.4 no signal
782 Disorientation 12 0.4 0.4 no signal
783 Feeling Abnormal 72 0.3 0.3 no signal
784 Intentional Overdose 19 0.3 0.3 no signal
785 Product Taste Abnormal 4 0.3 0.3 no signal
786 Oedema 16 0.3 0.3 no signal
787 Fluid Retention 15 0.3 0.3 no signal
788 Feeling Hot 18 0.3 0.3 no signal
789 Cough 82 0.3 0.3 no signal
790 Diabetic Ketoacidosis 7 0.3 0.3 no signal
791 Product Preparation Error 6 0.3 0.3 no signal
792 Dermatitis 6 0.3 0.3 no signal
793 Localised Infection 7 0.3 0.3 no signal
794 Balance Disorder 25 0.3 0.3 no signal
795 Swollen Tongue 9 0.3 0.3 no signal
796 Drug Abuse 24 0.3 0.3 no signal
797 Cold Sweat 5 0.3 0.3 no signal
798 Skin Discolouration 13 0.3 0.3 no signal
799 Diabetes Mellitus Inadequate Control 5 0.3 0.3 no signal
800 Pain In Jaw 8 0.3 0.3 no signal
801 Thirst 5 0.3 0.3 no signal
802 Toxicity To Various Agents 47 0.3 0.3 no signal
803 Gallbladder Disorder 5 0.3 0.3 no signal
804 Eczema 14 0.3 0.3 no signal
805 International Normalised Ratio Increased 8 0.3 0.3 no signal
806 Cellulitis 14 0.3 0.3 no signal
807 Rash Erythematous 13 0.3 0.3 no signal
808 Leukocytosis 5 0.3 0.3 no signal
809 Visual Impairment 34 0.3 0.3 no signal
810 Pulmonary Arterial Hypertension 4 0.3 0.3 no signal
811 Injection Site Nodule 3 0.3 0.3 no signal
812 Eye Pruritus 9 0.3 0.3 no signal
813 Loss Of Consciousness 35 0.3 0.3 no signal
814 Restlessness 10 0.3 0.3 no signal
815 Disease Recurrence 13 0.3 0.3 no signal
816 Neutrophil Count Decreased 11 0.3 0.3 no signal
817 Acute Myocardial Infarction 8 0.3 0.3 no signal
818 Blood Glucose Abnormal 5 0.3 0.3 no signal
819 Diplopia 7 0.3 0.3 no signal
820 Therapeutic Product Effect Incomplete 19 0.3 0.3 no signal
821 Chronic Obstructive Pulmonary Disease 14 0.3 0.3 no signal
822 Photophobia 5 0.3 0.3 no signal
823 Lung Disorder 13 0.3 0.3 no signal
824 Exposure Via Skin Contact 6 0.3 0.3 no signal
825 Skin Exfoliation 22 0.3 0.3 no signal
826 Cerebrovascular Accident 45 0.3 0.3 no signal
827 Device Failure 4 0.3 0.3 no signal
828 Blood Pressure Increased 40 0.3 0.3 no signal
829 Frequent Bowel Movements 7 0.3 0.3 no signal
830 Post Procedural Complication 5 0.3 0.3 no signal
831 Oropharyngeal Pain 24 0.3 0.3 no signal
832 Delusion 4 0.3 0.3 no signal
833 Oral Herpes 5 0.3 0.3 no signal
834 Hypoxia 9 0.3 0.3 no signal
835 Fall 85 0.3 0.3 no signal
836 Condition Aggravated 77 0.3 0.3 no signal
837 Eye Pain 14 0.3 0.3 no signal
838 Abscess 4 0.3 0.3 no signal
839 Blood Lactate Dehydrogenase Increased 4 0.3 0.3 no signal
840 Blister 14 0.3 0.3 no signal
841 Drug Intolerance 24 0.3 0.3 no signal
842 Presyncope 6 0.3 0.3 no signal
843 Palpitations 29 0.3 0.3 no signal
844 Mental Impairment 6 0.3 0.3 no signal
845 Urticaria 41 0.3 0.3 no signal
846 Swelling 23 0.3 0.3 no signal
847 Body Temperature Increased 5 0.3 0.3 no signal
848 Eye Swelling 9 0.3 0.3 no signal
849 Febrile Neutropenia 16 0.3 0.3 no signal
850 Surgery 14 0.3 0.3 no signal
851 Expired Product Administered 8 0.3 0.3 no signal
852 Dysgeusia 18 0.3 0.3 no signal
853 Pancreatic Carcinoma 7 0.3 0.3 no signal
854 Viral Infection 8 0.3 0.3 no signal
855 Urinary Retention 8 0.3 0.3 no signal
856 Dermatitis Atopic 12 0.3 0.3 no signal
857 Ageusia 6 0.3 0.3 no signal
858 Aggression 12 0.3 0.3 no signal
859 Hallucination, Visual 5 0.3 0.3 no signal
860 Pneumonia 77 0.3 0.3 no signal
861 Poisoning 3 0.3 0.3 no signal
862 Drug Ineffective 313 0.3 0.3 no signal
863 Hypersensitivity 44 0.3 0.3 no signal
864 Haematemesis 6 0.3 0.3 no signal
865 Anger 8 0.3 0.3 no signal
866 Device Use Error 8 0.3 0.3 no signal
867 Dry Mouth 19 0.3 0.3 no signal
868 Cardiac Disorder 22 0.3 0.3 no signal
869 Inflammation 12 0.3 0.3 no signal
870 Myocardial Infarction 41 0.3 0.3 no signal
871 Blood Potassium Decreased 7 0.3 0.3 no signal
872 Heart Rate Increased 23 0.3 0.3 no signal
873 Respiratory Tract Infection 6 0.3 0.3 no signal
874 Agitation 17 0.3 0.3 no signal
875 Clostridium Difficile Infection 5 0.3 0.3 no signal
876 Gastritis 6 0.3 0.3 no signal
877 Burning Sensation 16 0.3 0.3 no signal
878 Complication Associated With Device 3 0.3 0.3 no signal
879 Constipation 49 0.3 0.3 no signal
880 Acute Respiratory Distress Syndrome 4 0.3 0.3 no signal
881 Ear Infection 6 0.3 0.3 no signal
882 Extra Dose Administered 9 0.3 0.3 no signal
883 Therapeutic Response Unexpected 10 0.3 0.3 no signal
884 Uveitis 3 0.3 0.3 no signal
885 Product Administered At Inappropriate Site 4 0.3 0.3 no signal
886 Injection Site Mass 8 0.3 0.3 no signal
887 Upper Respiratory Tract Infection 10 0.3 0.3 no signal
888 Influenza 24 0.2 0.2 no signal
889 Haemoptysis 6 0.2 0.2 no signal
890 Amnesia 14 0.2 0.2 no signal
891 Somnolence 43 0.2 0.2 no signal
892 Speech Disorder 11 0.2 0.2 no signal
893 Cytokine Release Syndrome 4 0.2 0.2 no signal
894 Nervousness 11 0.2 0.2 no signal
895 Feeling Jittery 4 0.2 0.2 no signal
896 Hernia 4 0.2 0.2 no signal
897 Accidental Underdose 3 0.2 0.2 no signal
898 Dystonia 4 0.2 0.2 no signal
899 Vision Blurred 28 0.2 0.2 no signal
900 Haemorrhoids 4 0.2 0.2 no signal
901 Haemoglobin Decreased 21 0.2 0.2 no signal
902 Angioedema 9 0.2 0.2 no signal
903 Disability 4 0.2 0.2 no signal
904 Blood Pressure Abnormal 4 0.2 0.2 no signal
905 Adverse Drug Reaction 18 0.2 0.2 no signal
906 Blood Glucose Increased 38 0.2 0.2 no signal
907 Pneumonia Aspiration 5 0.2 0.2 no signal
908 Drug Withdrawal Syndrome Neonatal 3 0.2 0.2 no signal
909 Product Complaint 5 0.2 0.2 no signal
910 Anaphylactic Reaction 11 0.2 0.2 no signal
911 Cardiac Failure Congestive 16 0.2 0.2 no signal
912 Oedema Peripheral 24 0.2 0.2 no signal
913 Flushing 20 0.2 0.2 no signal
914 Intentional Product Misuse 17 0.2 0.2 no signal
915 Cardiovascular Disorder 5 0.2 0.2 no signal
916 Infection 28 0.2 0.2 no signal
917 Skin Ulcer 5 0.2 0.2 no signal
918 C-reactive Protein Increased 7 0.2 0.2 no signal
919 Malaise 84 0.2 0.2 no signal
920 Dry Skin 25 0.2 0.2 no signal
921 Platelet Count Decreased 20 0.2 0.2 no signal
922 Cardiac Failure 15 0.2 0.2 no signal
923 Pneumonitis 5 0.2 0.2 no signal
924 Injection Site Pain 56 0.2 0.2 no signal
925 Joint Swelling 22 0.2 0.2 no signal
926 Discomfort 11 0.2 0.2 no signal
927 Respiratory Distress 5 0.2 0.2 no signal
928 Diverticulitis 5 0.2 0.2 no signal
929 Fungal Infection 6 0.2 0.2 no signal
930 Hypotension 36 0.2 0.2 no signal
931 Pulmonary Embolism 17 0.2 0.2 no signal
932 Hyponatraemia 10 0.2 0.2 no signal
933 Depressed Level Of Consciousness 7 0.2 0.2 no signal
934 Heart Rate Irregular 4 0.2 0.2 no signal
935 Confusional State 28 0.2 0.2 no signal
936 Nasal Congestion 10 0.2 0.2 no signal
937 Rhinorrhoea 11 0.2 0.2 no signal
938 Wheezing 10 0.2 0.2 no signal
939 Cardiac Arrest 14 0.2 0.2 no signal
940 Interstitial Lung Disease 8 0.2 0.2 no signal
941 Sinusitis 17 0.2 0.2 no signal
942 Crying 6 0.2 0.2 no signal
943 Pleural Effusion 10 0.2 0.2 no signal
944 Haematochezia 9 0.2 0.2 no signal
945 Nasopharyngitis 30 0.2 0.2 no signal
946 Drug Hypersensitivity 31 0.2 0.2 no signal
947 Therapeutic Product Effect Decreased 7 0.2 0.2 no signal
948 Therapy Non-responder 7 0.2 0.2 no signal
949 Colitis Ulcerative 7 0.2 0.2 no signal
950 Throat Irritation 7 0.2 0.2 no signal
951 Cystitis 5 0.2 0.2 no signal
952 Gastric Cancer 4 0.2 0.2 no signal
953 Anaphylactic Shock 4 0.2 0.2 no signal
954 White Blood Cell Count Increased 6 0.2 0.2 no signal
955 Incorrect Dose Administered 35 0.2 0.2 no signal
956 Haematoma 4 0.2 0.2 no signal
957 Wrong Technique In Device Usage Process 7 0.2 0.2 no signal
958 Eye Disorder 5 0.2 0.2 no signal
959 Skin Irritation 7 0.2 0.2 no signal
960 Erythema 31 0.2 0.2 no signal
961 Lip Swelling 5 0.2 0.2 no signal
962 Injection Site Pruritus 10 0.2 0.2 no signal
963 Ocular Hyperaemia 7 0.2 0.2 no signal
964 Transient Ischaemic Attack 5 0.2 0.2 no signal
965 Injection Site Reaction 10 0.2 0.2 no signal
966 Acne 11 0.2 0.2 no signal
967 Tremor 24 0.2 0.2 no signal
968 Dementia 4 0.2 0.2 no signal
969 Atrial Fibrillation 14 0.2 0.2 no signal
970 Cardio-respiratory Arrest 6 0.2 0.2 no signal
971 Systemic Lupus Erythematosus 5 0.2 0.2 no signal
972 Cerebral Haemorrhage 5 0.2 0.2 no signal
973 Dysphonia 8 0.2 0.2 no signal
974 Tachycardia 12 0.2 0.2 no signal
975 Cataract 8 0.2 0.2 no signal
976 Therapeutic Response Decreased 8 0.2 0.2 no signal
977 Aphasia 4 0.2 0.2 no signal
978 Adverse Event 12 0.2 0.2 no signal
979 No Adverse Event 23 0.2 0.1 no signal
980 Arrhythmia 6 0.1 0.1 no signal
981 Drug Ineffective For Unapproved Indication 7 0.1 0.1 no signal
982 Contusion 12 0.1 0.1 no signal
983 Thrombosis 10 0.1 0.1 no signal
984 Rheumatoid Arthritis 14 0.1 0.1 no signal
985 Hepatic Cancer 3 0.1 0.1 no signal
986 Dyskinesia 5 0.1 0.1 no signal
987 Product Substitution Issue 7 0.1 0.1 no signal
988 Syncope 12 0.1 0.1 no signal
989 White Blood Cell Count Decreased 13 0.1 0.1 no signal
990 Device Dislocation 5 0.1 0.1 no signal
991 Bradycardia 6 0.1 0.1 no signal
992 Bronchitis 8 0.1 0.1 no signal
993 Deep Vein Thrombosis 7 0.1 0.1 no signal
994 Asthma 12 0.1 0.1 no signal
995 Overdose 23 0.1 0.1 no signal
996 Blood Pressure Decreased 7 0.1 0.1 no signal
997 Disease Progression 12 0.1 0.1 no signal
998 Injection Site Bruising 8 0.1 0.1 no signal
999 Psoriasis 13 0.1 0.1 no signal
1000 Blindness 4 0.1 0.1 no signal
1001 Epistaxis 7 0.1 0.1 no signal
1002 Eye Irritation 5 0.1 0.1 no signal
1003 Oxygen Saturation Decreased 5 0.1 0.1 no signal
1004 Product Quality Issue 12 0.1 0.1 no signal
1005 Myelosuppression 3 0.1 0.1 no signal
1006 Prostate Cancer 7 0.1 0.1 no signal
1007 Gastrointestinal Haemorrhage 7 0.1 0.1 no signal
1008 Dry Eye 4 0.1 0.1 no signal
1009 Device Breakage 3 0.1 0.1 no signal
1010 Malignant Neoplasm Progression 7 0.1 0.1 no signal
1011 Accidental Exposure To Product 6 0.1 0.1 no signal
1012 Completed Suicide 5 0.1 0.1 no signal
1013 Device Issue 5 0.1 0.1 no signal
1014 Injection Site Erythema 7 0.1 0.1 no signal
1015 Bladder Cancer 3 0.1 0.1 no signal
1016 Device Difficult To Use 3 0.1 0.1 no signal
1017 Drug Withdrawal Syndrome 4 0.1 0.1 no signal
1018 Breast Cancer 4 0.0 0.0 no signal
1019 Drug Dependence 4 0.0 0.0 no signal