Reaction

Protein Total Increased reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,618 reports · 69 co-occurring drugs

As of the last recalculation, Protein Total Increased appears in 2,618 FAERS reports alongside 69 co-occurring drug terms. The strongest observed disproportionality signal is EMTRICITABINE AND TENOFOVIR ALAFENAMIDE (PRR 41.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Emtricitabine And Tenofovir Alafenamide	58	41.6	41.8
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	91	41.3	41.5
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	44	39.5	39.7
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	49	39.4	39.6
Emtricitabine And Tenofovir Disoproxil Fumarate	200	37.7	37.8
Voclosporin	30	27.8	27.9
Tenofovir Disoproxil Fumarate	70	17.3	17.3
Chlorhexidine Gluconate	16	14.0	14.0
Ixazomib	44	12.3	12.4
Carfilzomib	42	12.0	12.0
Inclisiran	11	10.9	11.0
Calcium Gluconate	16	10.6	10.6
Bortezomib	105	9.7	9.7
Lenalidomide	430	9.5	9.5
Quinine	10	9.3	9.3
Fulvestrant	34	8.3	8.3
Thalidomide	35	7.7	7.7
Cladribine	9	7.5	7.5
Lisinopril And Hydrochlorothiazide Tablets	7	7.1	7.1
Atovaquone	7	6.9	6.9
Vemurafenib	10	6.6	6.6
Pomalidomide	81	6.4	6.4
Asfotase Alfa	8	6.4	6.4
Quetiapine Fumarate	23	6.2	6.2
Lisinopril And Hydrochlorothiazide	8	6.2	6.2
Letrozole Tablets	37	6.2	6.2
Prochlorperazine Maleate	7	6.1	6.1
Naproxen Sodium Tablet, Coated	10	5.9	5.9
Naproxen Sodium, Coated Tablets	10	5.9	5.9
Naproxen Sodium 220Mg	10	5.9	5.9
Paliperidone	17	5.8	5.8
Deferasirox	19	5.7	5.7
Letrozole	43	5.6	5.6
Zidovudine	9	5.4	5.4
Raltegravir	11	5.3	5.3
Dolutegravir Sodium	6	5.3	5.3
Lopinavir And Ritonavir	9	5.3	5.3
Thyroid, Porcine	7	5.2	5.2
Eplerenone	8	5.0	5.0
Axitinib	12	4.9	4.9
Acyclovir	68	4.8	4.8
Darunavir	9	4.7	4.7
Bendamustine Hcl	9	4.6	4.6
Dexamethasone 1.5 Mg	162	4.6	4.6
Acetaminophen And Codeine	7	4.6	4.6
Dexamethasone	162	4.6	4.6
Cortisone Acetate	7	4.5	4.5
Fosaprepitant Dimeglumine	7	4.1	4.1
Diclofenac Potassium, Film Coated	4	3.8	3.8
Diclofenac Potassium Tablets	4	3.8	3.8
Capecitabine	42	3.7	3.7
Diclofenac Potassium	5	3.7	3.7
Niraparib	10	3.6	3.6
Palbociclib	40	3.4	3.4
Paclitaxel (Aibumin-Bound)	32	3.1	3.1
Blinatumomab	4	3.1	3.1
Dofetilide	4	3.0	3.0
Cabozantinib	18	3.0	3.0
Paliperidone Palmitate	12	3.0	3.0
Pazopanib Hydrochloride	10	2.9	2.9
Clozapine	45	2.9	2.9
Daratumumab	13	2.6	2.6
Pseudoephedrine Hydrochloride	3	2.3	2.3
Patiromer	4	2.3	2.3
Glecaprevir And Pibrentasvir	3	2.2	2.2
Pseudoephedrine Hcl	3	2.2	2.2
Ledipasvir And Sofosbuvir	5	2.1	2.1
Diroximel Fumarate	3	2.0	2.0
Hydrocodone Bitartrate	9	1.6	1.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.