OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Canagliflozin

1,109 flagged reaction(s) · 80,286 total co-reports · max PRR 1,864.5
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Metatarsal Excision 102 1,864.5 1,870.9 signal
2 Limb Amputation 269 1,448.5 1,461.7 signal
3 Diabetic Foot Infection 834 1,007.5 1,036.5 signal
4 Osteomyelitis Acute 283 764.9 772.2 signal
5 Malignant Mediastinal Neoplasm 56 762.7 764.2 signal
6 Diabetic Neuropathic Ulcer 11 545.8 546.0 signal
7 Toe Amputation 2,195 535.9 578.5 signal
8 Foot Amputation 582 470.6 480.0 signal
9 Genital Infection Fungal 281 364.8 368.3 signal
10 Gas Gangrene 117 362.8 364.2 signal
11 Diabetic Ulcer 225 320.3 322.7 signal
12 Amputation 325 247.8 250.5 signal
13 Diabetic Foot 788 244.7 251.3 signal
14 Ischaemic Skin Ulcer 19 194.1 194.2 signal
15 Leg Amputation 792 167.3 171.8 signal
16 Osteomyelitis Chronic 114 158.4 159.0 signal
17 Dry Gangrene 114 155.0 155.6 signal
18 Gangrene 1,086 153.9 159.7 signal
19 Neuropathic Arthropathy 114 152.0 152.6 signal
20 Diabetic Gangrene 50 148.4 148.7 signal
21 Cellulitis Of Male External Genital Organ 16 118.2 118.3 signal
22 Diabetic Ketoacidosis 3,435 118.0 133.3 signal
23 Osteomyelitis 2,165 95.8 103.3 signal
24 Balanoposthitis 92 91.3 91.6 signal
25 Urine Output Increased 239 70.6 71.1 signal
26 Cellulitis Gangrenous 18 70.2 70.3 signal
27 Ketoacidosis 643 66.3 67.8 signal
28 Genital Infection 28 65.7 65.8 signal
29 Euglycaemic Diabetic Ketoacidosis 293 55.9 56.4 signal
30 Staphylococcal Osteomyelitis 13 52.2 52.2 signal
31 Vascular Stenosis 20 43.6 43.6 signal
32 Joint Ankylosis 33 43.0 43.1 signal
33 Urine Ketone Body 9 40.9 40.9 signal
34 Extremity Necrosis 95 40.3 40.4 signal
35 Ketonuria 41 37.5 37.5 signal
36 Urinary Tract Infection Fungal 28 36.4 36.4 signal
37 Blood Ketone Body 17 36.2 36.2 signal
38 Musculoskeletal Toxicity 9 36.1 36.1 signal
39 Urine Ketone Body Present 77 36.1 36.2 signal
40 Acetonaemia 12 35.8 35.8 signal
41 Necrotising Soft Tissue Infection 11 35.5 35.6 signal
42 Penile Infection 9 34.0 34.0 signal
43 Penile Erythema 17 33.3 33.3 signal
44 Glucose Urine Present 57 33.2 33.2 signal
45 Necrotising Oesophagitis 22 33.0 33.0 signal
46 Diabetic Ketosis 16 32.8 32.8 signal
47 Fungal Infection 1,447 32.0 33.6 signal
48 Vulvovaginitis 11 27.3 27.3 signal
49 Scrotal Abscess 14 27.1 27.1 signal
50 Blood Ketone Body Increased 28 26.3 26.3 signal
51 Ketosis 37 26.2 26.2 signal
52 Bone Cyst 33 25.6 25.6 signal
53 Fasciitis 23 25.6 25.6 signal
54 Necrotising Fasciitis 123 25.5 25.6 signal
55 Vulvovaginal Mycotic Infection 125 23.2 23.3 signal
56 Vulvitis 10 22.5 22.5 signal
57 Creatinine Renal Clearance Increased 23 22.2 22.2 signal
58 Necrosis Ischaemic 14 22.0 22.0 signal
59 Myopathy Toxic 18 21.9 21.9 signal
60 Genitourinary Tract Infection 8 21.6 21.6 signal
61 Genital Abscess 12 21.4 21.4 signal
62 Abscess Limb 125 21.3 21.3 signal
63 Phimosis 21 21.2 21.2 signal
64 Asthma-chronic Obstructive Pulmonary Disease Overlap Syndrome 15 20.9 20.9 signal
65 Cerebral Fungal Infection 8 20.7 20.7 signal
66 Microalbuminuria 21 20.0 20.0 signal
67 Bone Operation 18 19.8 19.8 signal
68 Abnormal Loss Of Weight 185 19.8 19.9 signal
69 Finger Amputation 20 19.8 19.8 signal
70 Peripheral Ischaemia 109 19.3 19.3 signal
71 Disability Assessment Scale Score Increased 8 18.6 18.6 signal
72 Therapeutic Response Increased 24 18.6 18.6 signal
73 Perineal Abscess 11 17.7 17.7 signal
74 Vulval Abscess 10 17.7 17.7 signal
75 Glycosuria 33 17.6 17.6 signal
76 Glycosylated Haemoglobin Decreased 37 16.7 16.8 signal
77 Blood Immunoglobulin E Increased 56 16.6 16.6 signal
78 Vulvovaginal Candidiasis 30 16.2 16.2 signal
79 Pruritus Genital 52 16.1 16.1 signal
80 Skin Ulcer 572 16.0 16.2 signal
81 Genital Rash 31 15.7 15.7 signal
82 Diabetic Gastroparesis 8 15.7 15.7 signal
83 Groin Abscess 25 15.4 15.4 signal
84 Albumin Urine Present 8 15.2 15.2 signal
85 Wound Necrosis 10 14.8 14.8 signal
86 Cellulitis 1,035 14.7 15.2 signal
87 Blood Uric Acid Decreased 10 14.7 14.8 signal
88 Glycosylated Haemoglobin Increased 515 14.7 14.9 signal
89 Glomerular Filtration Rate Decreased 243 14.4 14.5 signal
90 Soft Tissue Necrosis 13 13.5 13.5 signal
91 Anion Gap Increased 24 12.8 12.8 signal
92 Alanine Aminotransferase Abnormal 36 12.3 12.3 signal
93 Creatinine Renal Clearance Abnormal 8 12.2 12.2 signal
94 Vulvovaginal Pruritus 86 12.2 12.2 signal
95 Osteolysis 34 11.9 11.9 signal
96 Soft Tissue Injury 12 11.3 11.3 signal
97 Debridement 12 11.2 11.2 signal
98 Urosepsis 143 11.1 11.1 signal
99 Full Blood Count Abnormal 161 10.9 11.0 signal
100 Hepatic Fibrosis 51 10.7 10.7 signal
101 Renal Abscess 12 10.6 10.6 signal
102 Infected Skin Ulcer 28 10.6 10.6 signal
103 Metabolic Encephalopathy 44 10.5 10.5 signal
104 Hypertrophy 8 10.5 10.5 signal
105 Skin Injury 47 10.2 10.2 signal
106 Red Blood Cell Sedimentation Rate Abnormal 33 10.1 10.1 signal
107 Arthritis Bacterial 57 10.0 10.0 signal
108 Necrosis 74 9.4 9.5 signal
109 Acute Kidney Injury 1,998 9.4 10.0 signal
110 Steroid Diabetes 19 9.3 9.3 signal
111 Polyuria 106 9.2 9.3 signal
112 Micturition Disorder 44 9.1 9.1 signal
113 Hyperglycaemic Hyperosmolar Nonketotic Syndrome 14 9.0 9.0 signal
114 Perirectal Abscess 14 8.9 8.9 signal
115 Prostatitis 38 8.9 8.9 signal
116 Hemianopia Homonymous 9 8.8 8.8 signal
117 Metabolic Acidosis 383 8.6 8.7 signal
118 Polydipsia 47 8.5 8.5 signal
119 Pollakiuria 491 8.4 8.5 signal
120 Thirst 209 8.4 8.4 signal
121 Blood Pressure Diastolic Abnormal 30 8.3 8.3 signal
122 Genital Burning Sensation 10 8.2 8.2 signal
123 Blood Bicarbonate Decreased 22 8.2 8.2 signal
124 Pyelonephritis 99 8.2 8.2 signal
125 Vaginal Infection 54 8.2 8.2 signal
126 Extradural Abscess 9 8.1 8.1 signal
127 Bronchiectasis 75 8.0 8.0 signal
128 Glycosylated Haemoglobin Abnormal 13 7.8 7.8 signal
129 Breast Disorder 22 7.7 7.7 signal
130 Diabetes Mellitus Inadequate Control 189 7.6 7.6 signal
131 Drug Prescribing Error 205 7.5 7.5 signal
132 Acidosis 77 7.2 7.2 signal
133 Wound Dehiscence 34 7.1 7.1 signal
134 Fungal Skin Infection 40 7.1 7.1 signal
135 Cerebral Venous Sinus Thrombosis 8 6.9 6.9 signal
136 Pyelonephritis Acute 19 6.9 6.9 signal
137 Localised Infection 234 6.9 6.9 signal
138 Hypovolaemia 55 6.7 6.7 signal
139 Vaginal Disorder 9 6.7 6.7 signal
140 Bone Erosion 33 6.6 6.6 signal
141 Polycythaemia 19 6.6 6.6 signal
142 Blood Glucose Fluctuation 101 6.5 6.5 signal
143 Metabolic Surgery 10 6.4 6.4 signal
144 Mycobacterial Infection 15 6.2 6.2 signal
145 Pancreatitis Necrotising 18 5.6 5.6 signal
146 Rectal Abscess 13 5.5 5.5 signal
147 Postoperative Wound Infection 50 5.3 5.3 signal
148 Hyperglycaemia 264 5.2 5.2 signal
149 Penile Pain 22 5.1 5.1 signal
150 Diabetic Neuropathy 34 4.8 4.8 signal
151 Peripheral Arterial Occlusive Disease 28 4.8 4.8 signal
152 Respiratory Alkalosis 11 4.8 4.8 signal
153 Flank Pain 63 4.8 4.8 signal
154 Systemic Inflammatory Response Syndrome 25 4.7 4.7 signal
155 Pancreatitis 347 4.6 4.7 signal
156 Renal Pain 69 4.6 4.6 signal
157 Blood Glucose Increased 1,234 4.6 4.8 signal
158 Hyperkalaemia 226 4.6 4.6 signal
159 Lower Respiratory Tract Congestion 11 4.6 4.6 signal
160 Intensive Care 9 4.6 4.6 signal
161 Nocturia 77 4.5 4.5 signal
162 Insulin Resistance 13 4.5 4.5 signal
163 Type 2 Diabetes Mellitus 206 4.3 4.3 signal
164 Blood Pressure Systolic Abnormal 15 4.3 4.3 signal
165 Urinary Tract Infection 1,018 4.2 4.4 signal
166 Peripheral Vascular Disorder 31 4.2 4.2 signal
167 Blood Glucose Abnormal 110 4.2 4.2 signal
168 Tympanic Membrane Perforation 10 4.2 4.2 signal
169 Blood Glucose Decreased 282 4.1 4.2 signal
170 Blood Ph Decreased 10 4.1 4.1 signal
171 Blood Pressure Diastolic Decreased 43 4.1 4.1 signal
172 C-reactive Protein Abnormal 36 4.0 4.0 signal
173 Hypoglycaemia 272 4.0 4.0 signal
174 Pancreatitis Acute 125 4.0 4.0 signal
175 Urine Odour Abnormal 33 4.0 4.0 signal
176 Skin Necrosis 29 3.9 3.9 signal
177 Renal Tubular Acidosis 12 3.9 3.9 signal
178 Dehydration 730 3.9 3.9 signal
179 Oral Fungal Infection 15 3.9 3.9 signal
180 Genital Pain 8 3.8 3.8 signal
181 Renal Failure 711 3.8 3.8 signal
182 Diabetic Coma 15 3.8 3.8 signal
183 Vitamin B12 Decreased 15 3.7 3.7 signal
184 Low Density Lipoprotein Increased 40 3.7 3.7 signal
185 Urinary Tract Infection Bacterial 13 3.7 3.7 signal
186 Sepsis 573 3.6 3.7 signal
187 Hepatosplenomegaly 13 3.6 3.6 signal
188 Varices Oesophageal 15 3.5 3.5 signal
189 Impaired Healing 163 3.5 3.5 signal
190 Foot Deformity 55 3.5 3.5 signal
191 Trigger Finger 20 3.5 3.5 signal
192 Injection Site Nodule 54 3.5 3.5 signal
193 Dysuria 181 3.5 3.5 signal
194 Lactic Acidosis 157 3.5 3.5 signal
195 Weight Decreased 1,346 3.4 3.5 signal
196 Gastrointestinal Infection 43 3.4 3.4 signal
197 Blood Potassium Increased 78 3.4 3.4 signal
198 Adverse Event 440 3.4 3.4 signal
199 Intercepted Medication Error 22 3.3 3.3 signal
200 Haemoglobin Increased 21 3.3 3.3 signal
201 Hepatic Cirrhosis 87 3.3 3.3 signal
202 Urine Analysis Abnormal 14 3.3 3.3 signal
203 Anti-cyclic Citrullinated Peptide Antibody Positive 33 3.3 3.3 signal
204 Treatment Noncompliance 249 3.2 3.3 signal
205 Vulvovaginal Discomfort 20 3.2 3.2 signal
206 Diabetic Nephropathy 10 3.2 3.2 signal
207 Intentional Device Misuse 20 3.2 3.2 signal
208 Product Label Issue 30 3.2 3.2 signal
209 Blood Creatinine Decreased 14 3.2 3.2 signal
210 Bladder Spasm 8 3.0 3.0 signal
211 Anal Abscess 23 3.0 3.0 signal
212 Pancreatic Carcinoma Metastatic 12 3.0 3.0 signal
213 Impaired Gastric Emptying 53 2.9 2.9 signal
214 Wound Complication 14 2.9 2.9 signal
215 Renal Injury 122 2.9 2.9 signal
216 Micturition Urgency 46 2.9 2.9 signal
217 Vulvovaginal Dryness 13 2.9 2.9 signal
218 Blood Lactic Acid Increased 21 2.8 2.8 signal
219 Blood Pressure Systolic Decreased 18 2.8 2.8 signal
220 Creatinine Renal Clearance Decreased 16 2.8 2.8 signal
221 Haemorrhage Urinary Tract 10 2.8 2.8 signal
222 Staphylococcal Bacteraemia 17 2.8 2.8 signal
223 Gastroenteritis 57 2.8 2.8 signal
224 Diabetic Complication 10 2.8 2.8 signal
225 Escherichia Bacteraemia 9 2.7 2.7 signal
226 Blood Urine Present 74 2.7 2.7 signal
227 Hepatic Steatosis 72 2.7 2.7 signal
228 Hunger 52 2.7 2.7 signal
229 Dizziness Postural 37 2.7 2.7 signal
230 Body Temperature Fluctuation 8 2.7 2.7 signal
231 Hypernatraemia 19 2.7 2.7 signal
232 Pancreatitis Chronic 9 2.7 2.7 signal
233 Protein Urine Present 19 2.7 2.7 signal
234 Ingrowing Nail 9 2.7 2.7 signal
235 Urine Abnormality 17 2.7 2.7 signal
236 Urine Flow Decreased 9 2.7 2.7 signal
237 Hypovolaemic Shock 18 2.7 2.7 signal
238 Hypersensitivity Vasculitis 10 2.7 2.7 signal
239 Inappropriate Schedule Of Drug Administration 271 2.7 2.7 signal
240 Weight Fluctuation 39 2.6 2.6 signal
241 Blood Triglycerides Increased 66 2.6 2.6 signal
242 Finger Deformity 18 2.6 2.6 signal
243 Gastric Bypass 8 2.6 2.6 signal
244 Cystitis 117 2.6 2.6 signal
245 Candida Infection 61 2.6 2.6 signal
246 Food Craving 18 2.6 2.6 signal
247 Hydronephrosis 27 2.6 2.6 signal
248 Gastrointestinal Hypomotility 8 2.5 2.5 signal
249 Food Poisoning 19 2.5 2.5 signal
250 Blood Creatinine Increased 233 2.5 2.5 signal
251 Urinary Tract Disorder 16 2.5 2.5 signal
252 Lipase Increased 27 2.5 2.5 signal
253 Blood Count Abnormal 54 2.5 2.5 signal
254 Haematocrit Increased 8 2.5 2.5 signal
255 Kidney Infection 68 2.4 2.5 signal
256 Oral Candidiasis 45 2.4 2.4 signal
257 Multiple Allergies 27 2.4 2.4 signal
258 Wound Infection 37 2.4 2.4 signal
259 Subcutaneous Abscess 16 2.4 2.4 signal
260 Injection Site Extravasation 41 2.3 2.3 signal
261 Staphylococcal Sepsis 16 2.3 2.3 signal
262 Bladder Pain 10 2.2 2.2 signal
263 Vulvovaginal Burning Sensation 19 2.2 2.2 signal
264 Escherichia Sepsis 9 2.2 2.2 signal
265 Acute Respiratory Failure 59 2.2 2.2 signal
266 Hyperkeratosis 17 2.2 2.2 signal
267 Drug Dose Omission 514 2.2 2.2 signal
268 Diabetes Mellitus 234 2.2 2.2 signal
269 Renal Tubular Necrosis 30 2.2 2.2 signal
270 Foot Operation 15 2.2 2.2 signal
271 Toxic Encephalopathy 15 2.1 2.1 signal
272 Haematuria 104 2.1 2.1 signal
273 Nephrolithiasis 138 2.1 2.1 signal
274 Ulcer 48 2.1 2.1 signal
275 Incontinence 31 2.1 2.1 signal
276 Eructation 55 2.0 2.0 signal
277 Wound 80 2.0 2.0 signal
278 Endotracheal Intubation 8 2.0 2.0 no signal
279 Renal Impairment 237 2.0 2.0 no signal
280 Facial Paresis 10 2.0 2.0 no signal
281 Oesophageal Candidiasis 11 2.0 2.0 no signal
282 Nephrogenic Anaemia 13 2.0 2.0 no signal
283 Skin Abrasion 13 2.0 2.0 no signal
284 Nephropathy 26 2.0 2.0 no signal
285 Gastrooesophageal Reflux Disease 221 1.9 2.0 no signal
286 Sleep Disorder Due To A General Medical Condition 44 1.9 1.9 no signal
287 Bladder Disorder 27 1.9 1.9 no signal
288 Septic Shock 117 1.9 1.9 no signal
289 Acute Myocardial Infarction 80 1.9 1.9 no signal
290 Blood Creatine Increased 12 1.9 1.9 no signal
291 Injection Site Mass 98 1.9 1.9 no signal
292 Proctalgia 17 1.9 1.9 no signal
293 Diabetic Retinopathy 9 1.9 1.9 no signal
294 Abscess 42 1.9 1.9 no signal
295 Asthma 295 1.9 1.9 no signal
296 Blood Pressure Fluctuation 63 1.8 1.8 no signal
297 Nodule 34 1.8 1.8 no signal
298 Hand Deformity 34 1.8 1.8 no signal
299 Metabolic Disorder 15 1.8 1.8 no signal
300 Suspected Counterfeit Product 10 1.8 1.8 no signal
301 Hyperphagia 10 1.8 1.8 no signal
302 Orthostatic Hypotension 44 1.8 1.8 no signal
303 Body Temperature Decreased 25 1.8 1.8 no signal
304 Vulvovaginal Pain 12 1.8 1.8 no signal
305 Haemorrhagic Anaemia 11 1.7 1.7 no signal
306 Amylase Increased 9 1.7 1.7 no signal
307 Decubitus Ulcer 20 1.7 1.7 no signal
308 Bacterial Sepsis 8 1.7 1.7 no signal
309 Pancreatic Disorder 12 1.7 1.7 no signal
310 Hypophagia 61 1.7 1.7 no signal
311 Tenderness 25 1.7 1.7 no signal
312 Rash Generalised 62 1.7 1.7 no signal
313 Escherichia Urinary Tract Infection 10 1.7 1.7 no signal
314 Blood Creatinine Abnormal 8 1.6 1.6 no signal
315 Benign Prostatic Hyperplasia 12 1.6 1.6 no signal
316 Pharyngeal Oedema 36 1.6 1.6 no signal
317 Cholecystitis Acute 13 1.6 1.6 no signal
318 Urinary Incontinence 68 1.6 1.6 no signal
319 Prostatomegaly 9 1.6 1.6 no signal
320 Skin Odour Abnormal 9 1.6 1.6 no signal
321 Onychomycosis 10 1.6 1.6 no signal
322 Renal Disorder 106 1.6 1.6 no signal
323 Jaundice Cholestatic 8 1.6 1.6 no signal
324 Blood Urea Increased 38 1.6 1.6 no signal
325 Respiratory Rate Increased 20 1.6 1.6 no signal
326 Myocardial Infarction 394 1.6 1.6 no signal
327 Ligament Sprain 22 1.6 1.6 no signal
328 Nonspecific Reaction 12 1.6 1.6 no signal
329 Freezing Phenomenon 8 1.6 1.6 no signal
330 Pre-existing Condition Improved 14 1.6 1.6 no signal
331 Product Use Issue 410 1.5 1.6 no signal
332 Nephrotic Syndrome 15 1.5 1.5 no signal
333 Renal Function Test Abnormal 10 1.5 1.5 no signal
334 Blood Cholesterol Abnormal 10 1.5 1.5 no signal
335 Hallucination, Auditory 34 1.5 1.5 no signal
336 Obesity 34 1.5 1.5 no signal
337 Therapeutic Response Unexpected 95 1.5 1.5 no signal
338 Leukocytosis 38 1.5 1.5 no signal
339 Atrioventricular Block Complete 14 1.5 1.5 no signal
340 Wheezing 123 1.5 1.5 no signal
341 Blood Pressure Systolic Increased 40 1.4 1.4 no signal
342 Bacteraemia 24 1.4 1.4 no signal
343 Hypercalcaemia 25 1.4 1.4 no signal
344 Chronic Kidney Disease 155 1.4 1.4 no signal
345 Hyperchlorhydria 12 1.4 1.4 no signal
346 Psoriatic Arthropathy 81 1.4 1.4 no signal
347 Hepatic Enzyme Abnormal 10 1.4 1.4 no signal
348 Staphylococcal Infection 66 1.4 1.4 no signal
349 Sensory Loss 16 1.4 1.4 no signal
350 Drug Level Above Therapeutic 9 1.4 1.4 no signal
351 Obstructive Airways Disorder 22 1.4 1.4 no signal
352 Blood Pressure Diastolic Increased 9 1.4 1.4 no signal
353 Cerebrovascular Accident 326 1.4 1.4 no signal
354 Photopsia 12 1.3 1.3 no signal
355 Product Prescribing Error 45 1.3 1.3 no signal
356 Hepatocellular Injury 27 1.3 1.3 no signal
357 Furuncle 15 1.3 1.3 no signal
358 Pemphigoid 14 1.3 1.3 no signal
359 Large Intestine Polyp 13 1.3 1.3 no signal
360 Overweight 10 1.3 1.3 no signal
361 Dry Mouth 151 1.3 1.3 no signal
362 Blood Pressure Decreased 123 1.3 1.3 no signal
363 Chapped Lips 8 1.3 1.3 no signal
364 Foot Fracture 35 1.3 1.3 no signal
365 Cerebral Infarction 45 1.3 1.3 no signal
366 Polyp 12 1.3 1.3 no signal
367 Synovitis 33 1.3 1.3 no signal
368 Urine Output Decreased 16 1.3 1.3 no signal
369 Erectile Dysfunction 47 1.3 1.3 no signal
370 Mass 25 1.3 1.3 no signal
371 Angiopathy 10 1.2 1.2 no signal
372 Flatulence 100 1.2 1.2 no signal
373 Wrong Technique In Drug Usage Process 65 1.2 1.2 no signal
374 Incorrect Dose Administered 396 1.2 1.2 no signal
375 Transaminases Increased 39 1.2 1.2 no signal
376 Partial Seizures 9 1.2 1.2 no signal
377 Adverse Drug Reaction 156 1.2 1.2 no signal
378 Ear Disorder 8 1.2 1.2 no signal
379 Pruritus Generalised 38 1.2 1.2 no signal
380 Blood Potassium Decreased 52 1.2 1.2 no signal
381 Cardiovascular Disorder 44 1.2 1.2 no signal
382 Drug-induced Liver Injury 53 1.2 1.2 no signal
383 Hypertriglyceridaemia 10 1.2 1.2 no signal
384 Dizziness 843 1.2 1.2 no signal
385 Appetite Disorder 11 1.2 1.2 no signal
386 Muscle Atrophy 21 1.2 1.2 no signal
387 Gout 30 1.2 1.2 no signal
388 Injection Site Haemorrhage 132 1.2 1.2 no signal
389 Hypoacusis 71 1.2 1.2 no signal
390 Medication Residue Present 8 1.2 1.2 no signal
391 Facial Paralysis 14 1.2 1.2 no signal
392 Product Packaging Quantity Issue 18 1.2 1.2 no signal
393 Arterial Occlusive Disease 13 1.2 1.2 no signal
394 Cold Sweat 29 1.2 1.2 no signal
395 Vitamin D Decreased 14 1.2 1.2 no signal
396 Inflammatory Marker Increased 8 1.2 1.2 no signal
397 Blood Cholesterol Increased 76 1.1 1.1 no signal
398 Prostatic Disorder 9 1.1 1.1 no signal
399 Heart Rate Abnormal 9 1.1 1.1 no signal
400 Product Packaging Issue 15 1.1 1.1 no signal
401 Post Procedural Infection 13 1.1 1.1 no signal
402 Gastroenteritis Viral 29 1.1 1.1 no signal
403 Injury 113 1.1 1.1 no signal
404 Muscle Disorder 13 1.1 1.1 no signal
405 Arteriosclerosis 15 1.1 1.1 no signal
406 Rhabdomyolysis 66 1.1 1.1 no signal
407 Dyslipidaemia 8 1.1 1.1 no signal
408 Unevaluable Event 119 1.1 1.1 no signal
409 Drug Diversion 9 1.1 1.1 no signal
410 Feeling Jittery 30 1.1 1.1 no signal
411 Presyncope 38 1.1 1.1 no signal
412 Sleep Apnoea Syndrome 30 1.1 1.1 no signal
413 Carpal Tunnel Syndrome 22 1.1 1.1 no signal
414 Mouth Swelling 9 1.1 1.1 no signal
415 Chromaturia 35 1.1 1.1 no signal
416 Tooth Fracture 17 1.1 1.1 no signal
417 Nasal Congestion 90 1.1 1.1 no signal
418 Rhinorrhoea 98 1.1 1.1 no signal
419 C-reactive Protein Increased 55 1.1 1.1 no signal
420 Renal Cyst 12 1.1 1.1 no signal
421 Hypothyroidism 48 1.1 1.1 no signal
422 Hypokalaemia 69 1.1 1.1 no signal
423 Product Dose Omission 99 1.1 1.1 no signal
424 Heart Rate Increased 147 1.0 1.0 no signal
425 Blood Calcium Increased 13 1.0 1.0 no signal
426 Fracture 28 1.0 1.0 no signal
427 Back Injury 16 1.0 1.0 no signal
428 Limb Injury 40 1.0 1.0 no signal
429 Dialysis 21 1.0 1.0 no signal
430 Hypotension 295 1.0 1.0 no signal
431 End Stage Renal Disease 27 1.0 1.0 no signal
432 Accidental Exposure To Product By Child 10 1.0 1.0 no signal
433 Intestinal Ischaemia 8 1.0 1.0 no signal
434 Injection Site Injury 8 1.0 1.0 no signal
435 Injection Site Discomfort 15 1.0 1.0 no signal
436 Therapy Change 14 1.0 1.0 no signal
437 Joint Effusion 10 1.0 1.0 no signal
438 Hair Disorder 12 1.0 1.0 no signal
439 Increased Appetite 27 1.0 1.0 no signal
440 Skin Discolouration 66 1.0 1.0 no signal
441 Upper Respiratory Tract Infection 66 1.0 1.0 no signal
442 Encephalopathy 35 1.0 1.0 no signal
443 Lip Swelling 47 1.0 1.0 no signal
444 Dyspepsia 138 1.0 1.0 no signal
445 Sinus Congestion 19 1.0 1.0 no signal
446 Oxygen Saturation Decreased 78 1.0 1.0 no signal
447 Gallbladder Disorder 25 1.0 1.0 no signal
448 Vaginal Discharge 14 1.0 1.0 no signal
449 Faeces Soft 10 1.0 1.0 no signal
450 Peripheral Coldness 19 1.0 1.0 no signal
451 Incorrect Dose Administered By Device 35 1.0 1.0 no signal
452 Abdominal Discomfort 230 1.0 1.0 no signal
453 Hypophosphataemia 10 1.0 1.0 no signal
454 Muscle Tightness 22 1.0 1.0 no signal
455 Fibromyalgia 33 1.0 1.0 no signal
456 Poor Venous Access 14 1.0 1.0 no signal
457 Vomiting 634 1.0 1.0 no signal
458 Urinary Retention 45 1.0 1.0 no signal
459 Angina Pectoris 39 1.0 1.0 no signal
460 Back Disorder 22 0.9 0.9 no signal
461 Decreased Appetite 312 0.9 0.9 no signal
462 Hyperhidrosis 173 0.9 0.9 no signal
463 Blister 75 0.9 0.9 no signal
464 Frequent Bowel Movements 36 0.9 0.9 no signal
465 Underdose 97 0.9 0.9 no signal
466 Therapy Cessation 67 0.9 0.9 no signal
467 Iron Deficiency Anaemia 12 0.9 0.9 no signal
468 Coronary Artery Occlusion 18 0.9 0.9 no signal
469 Accidental Underdose 19 0.9 0.9 no signal
470 Prostatic Specific Antigen Increased 18 0.9 0.9 no signal
471 Body Height Decreased 14 0.9 0.9 no signal
472 Ischaemic Stroke 23 0.9 0.9 no signal
473 Nausea 1,015 0.9 0.9 no signal
474 Dry Throat 13 0.9 0.9 no signal
475 Lower Respiratory Tract Infection 58 0.9 0.9 no signal
476 Muscle Spasms 234 0.9 0.9 no signal
477 Blood Magnesium Decreased 11 0.9 0.9 no signal
478 Back Pain 296 0.9 0.9 no signal
479 Abdominal Pain 296 0.9 0.9 no signal
480 Pancreatic Carcinoma 37 0.9 0.9 no signal
481 Proteinuria 24 0.9 0.9 no signal
482 Lethargy 73 0.9 0.9 no signal
483 Dental Caries 14 0.9 0.9 no signal
484 Red Blood Cell Sedimentation Rate Increased 14 0.9 0.9 no signal
485 Groin Pain 11 0.9 0.9 no signal
486 Rotator Cuff Syndrome 16 0.9 0.9 no signal
487 Sensory Disturbance 20 0.9 0.9 no signal
488 Therapeutic Product Effect Decreased 55 0.9 0.9 no signal
489 Cardiac Flutter 8 0.9 0.9 no signal
490 Gastrointestinal Disorder 109 0.9 0.9 no signal
491 Facial Pain 11 0.9 0.9 no signal
492 Weight Increased 274 0.9 0.9 no signal
493 Tubulointerstitial Nephritis 23 0.9 0.9 no signal
494 Drug Dispensing Error 19 0.9 0.9 no signal
495 Escherichia Infection 10 0.9 0.9 no signal
496 Blindness Transient 9 0.9 0.9 no signal
497 Psychiatric Symptom 9 0.9 0.9 no signal
498 Electrolyte Imbalance 14 0.9 0.9 no signal
499 Eating Disorder 26 0.9 0.9 no signal
500 Diarrhoea 780 0.9 0.9 no signal
501 Blood Pressure Abnormal 24 0.9 0.9 no signal
502 Movement Disorder 39 0.9 0.9 no signal
503 Rash 524 0.9 0.8 no signal
504 Skin Disorder 40 0.8 0.8 no signal
505 Loss Of Personal Independence In Daily Activities 57 0.8 0.8 no signal
506 Sciatica 19 0.8 0.8 no signal
507 Retinal Detachment 11 0.8 0.8 no signal
508 Dysstasia 35 0.8 0.8 no signal
509 Wrong Technique In Product Usage Process 241 0.8 0.8 no signal
510 Abdominal Pain Upper 245 0.8 0.8 no signal
511 Blood Pressure Increased 182 0.8 0.8 no signal
512 Middle Insomnia 22 0.8 0.8 no signal
513 Cataract 70 0.8 0.8 no signal
514 Tooth Abscess 12 0.8 0.8 no signal
515 Feeling Abnormal 282 0.8 0.8 no signal
516 Off Label Use 1,016 0.8 0.8 no signal
517 Skin Infection 13 0.8 0.8 no signal
518 Constipation 252 0.8 0.8 no signal
519 Disability 23 0.8 0.8 no signal
520 Hysterectomy 10 0.8 0.8 no signal
521 Device Leakage 49 0.8 0.8 no signal
522 Abasia 29 0.8 0.8 no signal
523 Photosensitivity Reaction 19 0.8 0.8 no signal
524 Mental Impairment 28 0.8 0.8 no signal
525 Laceration 11 0.8 0.8 no signal
526 Swollen Tongue 36 0.8 0.8 no signal
527 Upper Limb Fracture 23 0.8 0.8 no signal
528 Arthropathy 64 0.8 0.8 no signal
529 Defaecation Urgency 8 0.8 0.8 no signal
530 Bedridden 15 0.8 0.8 no signal
531 Gastritis 30 0.8 0.8 no signal
532 Extrasystoles 8 0.8 0.8 no signal
533 Malaise 501 0.8 0.8 no signal
534 Surgery 66 0.8 0.8 no signal
535 Blindness Unilateral 16 0.8 0.8 no signal
536 Blood Creatine Phosphokinase Increased 33 0.8 0.8 no signal
537 Dermatitis Allergic 14 0.8 0.8 no signal
538 Impaired Work Ability 24 0.8 0.8 no signal
539 Oropharyngeal Discomfort 10 0.8 0.8 no signal
540 Needle Issue 32 0.8 0.8 no signal
541 Hypersomnia 32 0.8 0.8 no signal
542 Stent Placement 9 0.8 0.8 no signal
543 Hair Texture Abnormal 15 0.8 0.8 no signal
544 Respiratory Failure 81 0.8 0.8 no signal
545 Peripheral Swelling 170 0.8 0.8 no signal
546 Liver Disorder 49 0.8 0.8 no signal
547 Gastric Ulcer 21 0.8 0.8 no signal
548 Urticaria 183 0.8 0.8 no signal
549 Gastrointestinal Pain 12 0.8 0.8 no signal
550 Cholecystitis 13 0.8 0.8 no signal
551 Gastric Disorder 38 0.8 0.8 no signal
552 Dysgeusia 81 0.8 0.8 no signal
553 Retching 23 0.8 0.8 no signal
554 Infection 155 0.8 0.8 no signal
555 Spinal Operation 13 0.8 0.8 no signal
556 Seasonal Allergy 15 0.7 0.7 no signal
557 Scratch 11 0.7 0.7 no signal
558 Transient Ischaemic Attack 36 0.7 0.7 no signal
559 Haematemesis 27 0.7 0.7 no signal
560 Cardiac Operation 9 0.7 0.7 no signal
561 Product Odour Abnormal 11 0.7 0.7 no signal
562 Small Intestinal Obstruction 13 0.7 0.7 no signal
563 Syncope 106 0.7 0.7 no signal
564 Asthenia 398 0.7 0.7 no signal
565 Intentional Product Use Issue 93 0.7 0.7 no signal
566 Impaired Driving Ability 12 0.7 0.7 no signal
567 Secretion Discharge 13 0.7 0.7 no signal
568 Scar 18 0.7 0.7 no signal
569 Hallucination, Visual 22 0.7 0.7 no signal
570 Activities Of Daily Living Impaired 21 0.7 0.7 no signal
571 Neuropathy Peripheral 98 0.7 0.7 no signal
572 Intentional Product Misuse 90 0.7 0.7 no signal
573 Hair Colour Changes 13 0.7 0.7 no signal
574 Knee Operation 10 0.7 0.7 no signal
575 Road Traffic Accident 43 0.7 0.7 no signal
576 Madarosis 12 0.7 0.7 no signal
577 Rib Fracture 21 0.7 0.7 no signal
578 Spinal Osteoarthritis 9 0.7 0.7 no signal
579 Palpitations 119 0.7 0.7 no signal
580 Atrial Fibrillation 99 0.7 0.7 no signal
581 Productive Cough 48 0.7 0.7 no signal
582 Anal Incontinence 9 0.7 0.7 no signal
583 Blood Sodium Decreased 19 0.7 0.7 no signal
584 Hypomagnesaemia 14 0.7 0.7 no signal
585 Aphonia 14 0.7 0.7 no signal
586 Rash Pruritic 54 0.7 0.7 no signal
587 Hypertension 212 0.7 0.7 no signal
588 Chronic Obstructive Pulmonary Disease 52 0.7 0.7 no signal
589 Blood Test Abnormal 14 0.7 0.7 no signal
590 Wrong Drug Administered 9 0.7 0.7 no signal
591 Skin Lesion 27 0.7 0.7 no signal
592 Fall 329 0.7 0.7 no signal
593 Musculoskeletal Discomfort 17 0.7 0.7 no signal
594 Nephropathy Toxic 11 0.7 0.7 no signal
595 Nerve Injury 11 0.7 0.7 no signal
596 Exostosis 9 0.7 0.7 no signal
597 Loss Of Consciousness 126 0.7 0.7 no signal
598 Eye Infection 11 0.7 0.7 no signal
599 Oral Pain 22 0.7 0.7 no signal
600 Drug Level Decreased 10 0.7 0.7 no signal
601 Drug Intolerance 94 0.7 0.7 no signal
602 Abnormal Faeces 8 0.7 0.7 no signal
603 Cholelithiasis 32 0.7 0.7 no signal
604 Incorrect Product Storage 13 0.7 0.7 no signal
605 Thyroid Disorder 15 0.7 0.7 no signal
606 Device Related Infection 15 0.7 0.7 no signal
607 Depression 222 0.7 0.7 no signal
608 Myocarditis 11 0.7 0.7 no signal
609 Hypersensitivity 180 0.7 0.7 no signal
610 Burning Sensation 68 0.7 0.7 no signal
611 Libido Decreased 12 0.7 0.7 no signal
612 Erythema Multiforme 9 0.7 0.7 no signal
613 Pemphigus 12 0.7 0.7 no signal
614 Personality Change 9 0.7 0.7 no signal
615 Dyspnoea Exertional 36 0.7 0.7 no signal
616 Muscular Weakness 109 0.7 0.7 no signal
617 Acute Coronary Syndrome 8 0.7 0.7 no signal
618 Bladder Cancer 57 0.7 0.7 no signal
619 Swelling 89 0.7 0.7 no signal
620 Feeding Disorder 19 0.7 0.7 no signal
621 Nervousness 50 0.7 0.7 no signal
622 Neuralgia 23 0.7 0.7 no signal
623 Abdominal Distension 98 0.7 0.7 no signal
624 Musculoskeletal Disorder 18 0.7 0.7 no signal
625 Tooth Disorder 21 0.7 0.7 no signal
626 Swelling Face 61 0.7 0.7 no signal
627 Colon Cancer 14 0.7 0.7 no signal
628 Heart Rate Decreased 33 0.7 0.7 no signal
629 Restless Legs Syndrome 17 0.7 0.7 no signal
630 Covid-19 Pneumonia 11 0.7 0.7 no signal
631 Accident 11 0.7 0.7 no signal
632 Vitamin D Deficiency 9 0.7 0.7 no signal
633 Haemorrhoids 18 0.6 0.6 no signal
634 Hepatomegaly 9 0.6 0.6 no signal
635 Thyroid Cancer 11 0.6 0.6 no signal
636 Pain In Extremity 268 0.6 0.6 no signal
637 Hypoaesthesia 136 0.6 0.6 no signal
638 Abdominal Pain Lower 23 0.6 0.6 no signal
639 Drug Level Increased 15 0.6 0.6 no signal
640 Tendonitis 14 0.6 0.6 no signal
641 Chest Pain 167 0.6 0.6 no signal
642 Drug Administration Error 28 0.6 0.6 no signal
643 Joint Swelling 108 0.6 0.6 no signal
644 Drug Hypersensitivity 174 0.6 0.6 no signal
645 Hypokinesia 13 0.6 0.6 no signal
646 Vision Blurred 122 0.6 0.6 no signal
647 Eye Swelling 33 0.6 0.6 no signal
648 Alopecia 175 0.6 0.6 no signal
649 Drug Interaction 141 0.6 0.6 no signal
650 Tendon Rupture 11 0.6 0.6 no signal
651 Myalgia 151 0.6 0.6 no signal
652 Bronchitis 66 0.6 0.6 no signal
653 Pneumothorax 14 0.6 0.6 no signal
654 Arrhythmia 42 0.6 0.6 no signal
655 Cholecystectomy 10 0.6 0.6 no signal
656 Feeling Hot 54 0.6 0.6 no signal
657 Ear Discomfort 9 0.6 0.6 no signal
658 Prescribed Overdose 17 0.6 0.6 no signal
659 Choking 17 0.6 0.6 no signal
660 Injection Site Pruritus 58 0.6 0.6 no signal
661 Myocardial Ischaemia 10 0.6 0.6 no signal
662 Brain Oedema 11 0.6 0.6 no signal
663 Injection Site Irritation 11 0.6 0.6 no signal
664 Knee Arthroplasty 18 0.6 0.6 no signal
665 Oral Discomfort 12 0.6 0.6 no signal
666 Renal Failure Acute 37 0.6 0.6 no signal
667 Intervertebral Disc Degeneration 8 0.6 0.6 no signal
668 Musculoskeletal Stiffness 75 0.6 0.6 no signal
669 Head Injury 27 0.6 0.6 no signal
670 Stress 61 0.6 0.6 no signal
671 Sputum Discoloured 8 0.6 0.6 no signal
672 Breast Pain 9 0.6 0.6 no signal
673 Dyspnoea 477 0.6 0.6 no signal
674 Balance Disorder 73 0.6 0.6 no signal
675 Amnesia 55 0.6 0.6 no signal
676 Drug Effect Incomplete 31 0.6 0.6 no signal
677 Confusional State 136 0.6 0.6 no signal
678 Ageusia 21 0.6 0.6 no signal
679 Gait Disturbance 161 0.6 0.6 no signal
680 Hepatic Enzyme Increased 57 0.6 0.6 no signal
681 Ankle Fracture 13 0.6 0.6 no signal
682 Muscle Rigidity 10 0.6 0.6 no signal
683 Heart Rate Irregular 19 0.6 0.6 no signal
684 Immune System Disorder 11 0.6 0.6 no signal
685 Paraesthesia Oral 12 0.6 0.6 no signal
686 Hyperlipidaemia 10 0.6 0.6 no signal
687 Glaucoma 16 0.6 0.6 no signal
688 Medication Error 46 0.6 0.6 no signal
689 Cough 231 0.6 0.6 no signal
690 Discomfort 50 0.6 0.6 no signal
691 Injection Site Bruising 65 0.6 0.6 no signal
692 Sars-cov-2 Test Positive 11 0.6 0.6 no signal
693 Pruritus 311 0.6 0.6 no signal
694 Joint Range Of Motion Decreased 11 0.6 0.6 no signal
695 Tachycardia 73 0.6 0.6 no signal
696 Intervertebral Disc Protrusion 18 0.6 0.6 no signal
697 Bone Disorder 15 0.6 0.6 no signal
698 Jaundice 22 0.6 0.6 no signal
699 Laboratory Test Abnormal 24 0.6 0.6 no signal
700 Psychotic Disorder 24 0.6 0.6 no signal
701 Gastrointestinal Haemorrhage 68 0.6 0.6 no signal
702 Visual Impairment 99 0.6 0.6 no signal
703 Thinking Abnormal 15 0.6 0.6 no signal
704 Arthritis 63 0.6 0.6 no signal
705 Hypoaesthesia Oral 12 0.6 0.6 no signal
706 Joint Injury 17 0.6 0.6 no signal
707 Angioedema 35 0.6 0.6 no signal
708 Sinusitis 81 0.6 0.6 no signal
709 Lower Limb Fracture 15 0.6 0.6 no signal
710 Initial Insomnia 8 0.6 0.6 no signal
711 Ventricular Tachycardia 13 0.6 0.6 no signal
712 Disorientation 31 0.5 0.5 no signal
713 Nasopharyngitis 144 0.5 0.5 no signal
714 Post Procedural Complication 15 0.5 0.5 no signal
715 Rheumatoid Arthritis 88 0.5 0.5 no signal
716 Fatigue 604 0.5 0.5 no signal
717 Osteoarthritis 33 0.5 0.5 no signal
718 Cardiac Failure Congestive 63 0.5 0.5 no signal
719 Oedema 42 0.5 0.5 no signal
720 Fear 21 0.5 0.5 no signal
721 Influenza Like Illness 64 0.5 0.5 no signal
722 Toothache 14 0.5 0.5 no signal
723 Headache 484 0.5 0.5 no signal
724 Contusion 74 0.5 0.5 no signal
725 Drug Ineffective 1,012 0.5 0.5 no signal
726 Oropharyngeal Pain 71 0.5 0.5 no signal
727 Arthralgia 317 0.5 0.5 no signal
728 Hyponatraemia 43 0.5 0.5 no signal
729 Therapeutic Product Effect Incomplete 54 0.5 0.5 no signal
730 Hemiparesis 13 0.5 0.5 no signal
731 Hepatic Failure 23 0.5 0.5 no signal
732 Transfusion 8 0.5 0.5 no signal
733 Ovarian Cancer 7 0.5 0.5 no signal
734 Liver Function Test Abnormal 22 0.5 0.5 no signal
735 Vaginal Haemorrhage 32 0.5 0.5 no signal
736 Wrist Fracture 9 0.5 0.5 no signal
737 Hepatic Encephalopathy 7 0.5 0.5 no signal
738 Poor Quality Sleep 16 0.5 0.5 no signal
739 Epistaxis 56 0.5 0.5 no signal
740 Cardiac Failure 60 0.5 0.5 no signal
741 Shock 17 0.5 0.5 no signal
742 Liver Injury 18 0.5 0.5 no signal
743 Colitis 28 0.5 0.5 no signal
744 Suicidal Ideation 68 0.5 0.5 no signal
745 Product Use In Unapproved Indication 181 0.5 0.5 no signal
746 Blindness 30 0.5 0.5 no signal
747 Generalised Tonic-clonic Seizure 12 0.5 0.5 no signal
748 Pallor 20 0.5 0.5 no signal
749 Pulmonary Thrombosis 8 0.5 0.5 no signal
750 Hypercholesterolaemia 7 0.5 0.5 no signal
751 Oesophagitis 8 0.5 0.5 no signal
752 Generalised Oedema 9 0.5 0.5 no signal
753 White Blood Cell Count Increased 28 0.5 0.5 no signal
754 Rash Erythematous 34 0.5 0.5 no signal
755 Speech Disorder 38 0.5 0.5 no signal
756 Influenza 81 0.5 0.5 no signal
757 Diverticulitis 20 0.5 0.5 no signal
758 Paraesthesia 114 0.5 0.5 no signal
759 Coronary Artery Disease 22 0.5 0.5 no signal
760 Ear Pain 14 0.5 0.5 no signal
761 Stevens-johnson Syndrome 16 0.5 0.5 no signal
762 Feeling Cold 20 0.5 0.5 no signal
763 Alanine Aminotransferase Increased 44 0.5 0.5 no signal
764 Tremor 119 0.5 0.5 no signal
765 Ear Infection 19 0.5 0.5 no signal
766 Pelvic Pain 13 0.5 0.5 no signal
767 Coeliac Disease 7 0.5 0.5 no signal
768 Inability To Afford Medication 7 0.5 0.5 no signal
769 Upper Gastrointestinal Haemorrhage 12 0.5 0.5 no signal
770 Limb Discomfort 22 0.5 0.5 no signal
771 Hepatitis 18 0.5 0.5 no signal
772 Depressed Mood 37 0.5 0.5 no signal
773 Cardiogenic Shock 10 0.5 0.5 no signal
774 Musculoskeletal Pain 37 0.5 0.5 no signal
775 Internal Haemorrhage 8 0.5 0.5 no signal
776 Product Quality Issue 94 0.5 0.5 no signal
777 Rectal Haemorrhage 30 0.5 0.5 no signal
778 Pain 426 0.5 0.5 no signal
779 Respiratory Tract Congestion 11 0.5 0.5 no signal
780 Haematochezia 38 0.5 0.5 no signal
781 Sluggishness 7 0.5 0.5 no signal
782 Deep Vein Thrombosis 45 0.5 0.5 no signal
783 Vasculitis 8 0.5 0.5 no signal
784 Temperature Intolerance 7 0.5 0.5 no signal
785 Post Procedural Haemorrhage 8 0.5 0.5 no signal
786 Dysphonia 40 0.5 0.5 no signal
787 Tooth Infection 9 0.5 0.5 no signal
788 Drug Eruption 12 0.5 0.5 no signal
789 Euphoric Mood 7 0.5 0.5 no signal
790 Extra Dose Administered 27 0.5 0.5 no signal
791 Chest Discomfort 69 0.5 0.5 no signal
792 Dermatitis 14 0.5 0.5 no signal
793 Hepatic Function Abnormal 25 0.5 0.5 no signal
794 Pulmonary Mass 10 0.5 0.5 no signal
795 Macular Degeneration 8 0.5 0.5 no signal
796 Cardiac Disorder 63 0.5 0.5 no signal
797 Thrombosis 54 0.5 0.5 no signal
798 Memory Impairment 92 0.5 0.5 no signal
799 Injection Site Pain 203 0.5 0.5 no signal
800 Fluid Retention 34 0.5 0.5 no signal
801 Disturbance In Attention 36 0.5 0.5 no signal
802 Mouth Ulceration 14 0.5 0.5 no signal
803 Blood Bilirubin Increased 18 0.5 0.5 no signal
804 Irritability 40 0.5 0.5 no signal
805 Anaphylactic Shock 17 0.5 0.5 no signal
806 Therapeutic Response Decreased 40 0.5 0.5 no signal
807 Nightmare 23 0.5 0.5 no signal
808 Therapeutic Response Shortened 21 0.5 0.5 no signal
809 Device Failure 10 0.5 0.5 no signal
810 Sleep Disorder 46 0.5 0.5 no signal
811 Respiratory Tract Infection 17 0.5 0.5 no signal
812 Product Physical Issue 13 0.5 0.5 no signal
813 Product Administration Error 13 0.5 0.5 no signal
814 Nerve Compression 6 0.5 0.5 no signal
815 Ileus 8 0.5 0.5 no signal
816 Pneumonia 210 0.5 0.5 no signal
817 Muscle Twitching 15 0.5 0.5 no signal
818 Economic Problem 10 0.5 0.5 no signal
819 Faeces Discoloured 14 0.5 0.5 no signal
820 Appendicitis 6 0.5 0.5 no signal
821 Laryngitis 7 0.5 0.5 no signal
822 Ocular Discomfort 7 0.5 0.5 no signal
823 Cyst 8 0.5 0.5 no signal
824 Pharyngitis 8 0.5 0.5 no signal
825 Eye Disorder 21 0.5 0.5 no signal
826 Coordination Abnormal 9 0.5 0.5 no signal
827 Diarrhoea Haemorrhagic 6 0.5 0.5 no signal
828 Vertigo 39 0.5 0.4 no signal
829 Eye Inflammation 6 0.4 0.4 no signal
830 Melaena 14 0.4 0.4 no signal
831 Insomnia 169 0.4 0.4 no signal
832 Osteonecrosis 21 0.4 0.4 no signal
833 Rash Macular 22 0.4 0.4 no signal
834 Viral Infection 21 0.4 0.4 no signal
835 Tinnitus 29 0.4 0.4 no signal
836 Accidental Overdose 23 0.4 0.4 no signal
837 Colitis Ulcerative 28 0.4 0.4 no signal
838 Psoriasis 82 0.4 0.4 no signal
839 Skin Haemorrhage 9 0.4 0.4 no signal
840 Inflammation 32 0.4 0.4 no signal
841 Unresponsive To Stimuli 16 0.4 0.4 no signal
842 Hospitalisation 94 0.4 0.4 no signal
843 Wrong Technique In Device Usage Process 28 0.4 0.4 no signal
844 Multiple Organ Dysfunction Syndrome 17 0.4 0.4 no signal
845 Neck Pain 34 0.4 0.4 no signal
846 Nervous System Disorder 19 0.4 0.4 no signal
847 Pneumonia Aspiration 15 0.4 0.4 no signal
848 Coagulopathy 10 0.4 0.4 no signal
849 Psychomotor Hyperactivity 10 0.4 0.4 no signal
850 Taste Disorder 12 0.4 0.4 no signal
851 Toxic Epidermal Necrolysis 9 0.4 0.4 no signal
852 Device Malfunction 40 0.4 0.4 no signal
853 Lymphadenopathy 21 0.4 0.4 no signal
854 Bacterial Infection 11 0.4 0.4 no signal
855 Hip Fracture 19 0.4 0.4 no signal
856 Dysphagia 56 0.4 0.4 no signal
857 Helicobacter Infection 6 0.4 0.4 no signal
858 Subarachnoid Haemorrhage 6 0.4 0.4 no signal
859 Somnolence 118 0.4 0.4 no signal
860 Treatment Failure 48 0.4 0.4 no signal
861 Adrenal Insufficiency 7 0.4 0.4 no signal
862 Neutrophil Count Increased 6 0.4 0.4 no signal
863 Mobility Decreased 41 0.4 0.4 no signal
864 Lung Disorder 28 0.4 0.4 no signal
865 Neoplasm Malignant 38 0.4 0.4 no signal
866 Visual Acuity Reduced 19 0.4 0.4 no signal
867 Disseminated Intravascular Coagulation 8 0.4 0.4 no signal
868 Blood Alkaline Phosphatase Increased 14 0.4 0.4 no signal
869 Sudden Death 6 0.4 0.4 no signal
870 Anger 19 0.4 0.4 no signal
871 Pulmonary Oedema 25 0.4 0.4 no signal
872 Drug Ineffective For Unapproved Indication 31 0.4 0.4 no signal
873 Herpes Zoster 32 0.4 0.4 no signal
874 Pulmonary Embolism 53 0.4 0.4 no signal
875 Sinus Disorder 11 0.4 0.4 no signal
876 Inappropriate Schedule Of Product Administration 98 0.4 0.4 no signal
877 Apathy 8 0.4 0.4 no signal
878 Delirium 19 0.4 0.4 no signal
879 Anaphylactic Reaction 30 0.4 0.4 no signal
880 Bone Pain 32 0.4 0.4 no signal
881 Coma 26 0.4 0.4 no signal
882 Conjunctivitis 10 0.4 0.4 no signal
883 Cardiomyopathy 8 0.4 0.4 no signal
884 Circumstance Or Information Capable Of Leading To Medication Error 18 0.4 0.4 no signal
885 Injection Site Urticaria 13 0.4 0.4 no signal
886 Platelet Count Increased 7 0.4 0.4 no signal
887 Deafness 14 0.4 0.4 no signal
888 Therapy Partial Responder 8 0.4 0.4 no signal
889 Erythema 109 0.4 0.4 no signal
890 Squamous Cell Carcinoma 5 0.4 0.4 no signal
891 Leukaemia 5 0.4 0.4 no signal
892 Hypocalcaemia 10 0.4 0.4 no signal
893 Skin Fissures 10 0.4 0.4 no signal
894 Agitation 39 0.4 0.4 no signal
895 Pulmonary Congestion 7 0.4 0.4 no signal
896 Dermatitis Contact 6 0.4 0.4 no signal
897 Posterior Reversible Encephalopathy Syndrome 5 0.4 0.4 no signal
898 Eye Pain 29 0.4 0.4 no signal
899 Neoplasm 6 0.4 0.4 no signal
900 Chills 61 0.4 0.4 no signal
901 Anxiety 148 0.4 0.4 no signal
902 Musculoskeletal Chest Pain 8 0.4 0.4 no signal
903 Eye Pruritus 17 0.4 0.4 no signal
904 Irritable Bowel Syndrome 11 0.4 0.4 no signal
905 Vitreous Floaters 5 0.4 0.4 no signal
906 Pyrexia 177 0.4 0.4 no signal
907 Head Discomfort 9 0.4 0.4 no signal
908 Blood Iron Decreased 6 0.4 0.4 no signal
909 Clostridium Difficile Infection 11 0.4 0.4 no signal
910 Hot Flush 38 0.4 0.4 no signal
911 Mental Status Changes 14 0.4 0.4 no signal
912 Mood Swings 16 0.4 0.4 no signal
913 Diplopia 13 0.4 0.4 no signal
914 Respiratory Disorder 15 0.4 0.4 no signal
915 Cardiac Arrest 41 0.3 0.3 no signal
916 Drug Effect Decreased 27 0.3 0.3 no signal
917 Hallucination 37 0.3 0.3 no signal
918 Hypothermia 5 0.3 0.3 no signal
919 Device Issue 43 0.3 0.3 no signal
920 Sneezing 11 0.3 0.3 no signal
921 Covid-19 87 0.3 0.3 no signal
922 Oedema Peripheral 60 0.3 0.3 no signal
923 Rash Papular 11 0.3 0.3 no signal
924 Aspartate Aminotransferase Increased 26 0.3 0.3 no signal
925 Bradycardia 26 0.3 0.3 no signal
926 Impaired Quality Of Life 7 0.3 0.3 no signal
927 Intentional Overdose 31 0.3 0.3 no signal
928 Osteoporosis 20 0.3 0.3 no signal
929 Hypoxia 17 0.3 0.3 no signal
930 Injection Site Discolouration 6 0.3 0.3 no signal
931 Hyperthyroidism 7 0.3 0.3 no signal
932 Anosmia 7 0.3 0.3 no signal
933 Expired Product Administered 16 0.3 0.3 no signal
934 Tooth Extraction 6 0.3 0.3 no signal
935 Renal Cancer 23 0.3 0.3 no signal
936 Cardio-respiratory Arrest 20 0.3 0.3 no signal
937 Ocular Hyperaemia 22 0.3 0.3 no signal
938 Throat Irritation 21 0.3 0.3 no signal
939 Skin Exfoliation 39 0.3 0.3 no signal
940 Gastric Cancer 12 0.3 0.3 no signal
941 Circulatory Collapse 8 0.3 0.3 no signal
942 Abnormal Dreams 13 0.3 0.3 no signal
943 Decreased Activity 5 0.3 0.3 no signal
944 Skin Cancer 10 0.3 0.3 no signal
945 Device Use Issue 8 0.3 0.3 no signal
946 Paranoia 8 0.3 0.3 no signal
947 Pharyngitis Streptococcal 5 0.3 0.3 no signal
948 Haematoma 12 0.3 0.3 no signal
949 Condition Aggravated 139 0.3 0.3 no signal
950 Mental Disorder 20 0.3 0.3 no signal
951 Joint Stiffness 12 0.3 0.3 no signal
952 Bipolar Disorder 5 0.3 0.3 no signal
953 Metastases To Liver 8 0.3 0.3 no signal
954 Application Site Pain 10 0.3 0.3 no signal
955 Gait Inability 15 0.3 0.3 no signal
956 Local Swelling 8 0.3 0.3 no signal
957 Adverse Reaction 6 0.3 0.3 no signal
958 International Normalised Ratio Increased 13 0.3 0.3 no signal
959 Abnormal Behaviour 18 0.3 0.3 no signal
960 Seizure 51 0.3 0.3 no signal
961 Fistula 5 0.3 0.3 no signal
962 Tachypnoea 6 0.3 0.3 no signal
963 Flushing 45 0.3 0.3 no signal
964 Brain Neoplasm 4 0.3 0.3 no signal
965 Lacrimation Increased 13 0.3 0.3 no signal
966 Device Occlusion 6 0.3 0.3 no signal
967 Stomatitis 26 0.3 0.3 no signal
968 Pleural Effusion 26 0.3 0.3 no signal
969 Injection Site Swelling 32 0.3 0.3 no signal
970 Migraine 40 0.3 0.3 no signal
971 Neuroleptic Malignant Syndrome 5 0.3 0.3 no signal
972 Ataxia 5 0.3 0.3 no signal
973 Femur Fracture 13 0.3 0.3 no signal
974 Product Dose Omission Issue 119 0.3 0.3 no signal
975 Subdural Haematoma 6 0.3 0.3 no signal
976 Anhedonia 11 0.3 0.3 no signal
977 Injection Site Erythema 51 0.3 0.3 no signal
978 Face Oedema 7 0.3 0.3 no signal
979 Hepatic Cancer 10 0.3 0.3 no signal
980 Illness 41 0.3 0.3 no signal
981 Ascites 12 0.3 0.3 no signal
982 Throat Tightness 11 0.3 0.3 no signal
983 Hospice Care 4 0.3 0.3 no signal
984 Depressed Level Of Consciousness 16 0.3 0.3 no signal
985 No Therapeutic Response 5 0.3 0.3 no signal
986 Spinal Fracture 8 0.3 0.3 no signal
987 Prescribed Underdose 8 0.3 0.3 no signal
988 Intestinal Obstruction 15 0.3 0.3 no signal
989 Salivary Hypersecretion 4 0.3 0.3 no signal
990 Haemorrhage Intracranial 6 0.3 0.3 no signal
991 Poisoning 5 0.3 0.3 no signal
992 Injection Site Rash 12 0.3 0.3 no signal
993 Hip Arthroplasty 6 0.3 0.3 no signal
994 Dementia 11 0.3 0.3 no signal
995 Platelet Count Decreased 42 0.3 0.3 no signal
996 Infusion Related Reaction 26 0.3 0.3 no signal
997 Injection Site Reaction 27 0.3 0.3 no signal
998 Pericardial Effusion 9 0.3 0.3 no signal
999 Pain In Jaw 11 0.3 0.3 no signal
1000 Lymphoma 6 0.3 0.3 no signal
1001 Product Use Complaint 6 0.3 0.3 no signal
1002 Cognitive Disorder 18 0.3 0.3 no signal
1003 Hereditary Angioedema 4 0.3 0.3 no signal
1004 Eye Haemorrhage 5 0.3 0.3 no signal
1005 Product Taste Abnormal 5 0.3 0.3 no signal
1006 Uveitis 5 0.3 0.3 no signal
1007 Mood Altered 10 0.3 0.3 no signal
1008 Anaemia 70 0.3 0.3 no signal
1009 Cholestasis 7 0.3 0.3 no signal
1010 Gingival Bleeding 5 0.3 0.3 no signal
1011 Cerebral Haemorrhage 13 0.3 0.3 no signal
1012 Haemorrhage 38 0.3 0.3 no signal
1013 Aphasia 11 0.3 0.3 no signal
1014 Eczema 18 0.3 0.3 no signal
1015 Haemoptysis 10 0.3 0.3 no signal
1016 Panic Attack 13 0.3 0.3 no signal
1017 Drug Resistance 9 0.2 0.2 no signal
1018 Red Blood Cell Count Decreased 10 0.2 0.2 no signal
1019 Bone Density Decreased 11 0.2 0.2 no signal
1020 Dysarthria 13 0.2 0.2 no signal
1021 Ill-defined Disorder 21 0.2 0.2 no signal
1022 Device Delivery System Issue 9 0.2 0.2 no signal
1023 Sexual Dysfunction 4 0.2 0.2 no signal
1024 Toxicity To Various Agents 57 0.2 0.2 no signal
1025 Contraindicated Product Administered 10 0.2 0.2 no signal
1026 Intentional Dose Omission 9 0.2 0.2 no signal
1027 Skin Irritation 15 0.2 0.2 no signal
1028 Respiratory Distress 9 0.2 0.2 no signal
1029 Product Dispensing Error 7 0.2 0.2 no signal
1030 Glossodynia 7 0.2 0.2 no signal
1031 Intraocular Pressure Increased 4 0.2 0.2 no signal
1032 Dry Eye 15 0.2 0.2 no signal
1033 Ankylosing Spondylitis 4 0.2 0.2 no signal
1034 General Physical Health Deterioration 35 0.2 0.2 no signal
1035 Mania 5 0.2 0.2 no signal
1036 Crying 11 0.2 0.2 no signal
1037 Haemoglobin Decreased 31 0.2 0.2 no signal
1038 Menorrhagia 6 0.2 0.2 no signal
1039 Palmar-plantar Erythrodysaesthesia Syndrome 7 0.2 0.2 no signal
1040 Injury Associated With Device 6 0.2 0.2 no signal
1041 Incorrect Product Administration Duration 6 0.2 0.2 no signal
1042 Acute Hepatic Failure 4 0.2 0.2 no signal
1043 Product Preparation Error 6 0.2 0.2 no signal
1044 Emotional Distress 35 0.2 0.2 no signal
1045 Night Sweats 9 0.2 0.2 no signal
1046 Death 240 0.2 0.2 no signal
1047 Acne 21 0.2 0.2 no signal
1048 Fluid Overload 4 0.2 0.2 no signal
1049 Therapy Non-responder 12 0.2 0.2 no signal
1050 Eye Irritation 15 0.2 0.2 no signal
1051 Dry Skin 35 0.2 0.2 no signal
1052 Product Storage Error 23 0.2 0.2 no signal
1053 Rebound Effect 3 0.2 0.2 no signal
1054 Device Use Error 9 0.2 0.2 no signal
1055 Bone Loss 4 0.2 0.2 no signal
1056 Withdrawal Syndrome 11 0.2 0.2 no signal
1057 Metastases To Lung 3 0.2 0.2 no signal
1058 Procedural Pain 7 0.2 0.2 no signal
1059 Electrocardiogram Qt Prolonged 9 0.2 0.2 no signal
1060 Neutrophil Count Decreased 10 0.2 0.2 no signal
1061 Schizophrenia 3 0.2 0.2 no signal
1062 Prostate Cancer 20 0.2 0.2 no signal
1063 Product Substitution Issue 14 0.2 0.2 no signal
1064 Lung Neoplasm Malignant 10 0.2 0.2 no signal
1065 Muscle Spasticity 3 0.2 0.2 no signal
1066 Abnormal Weight Gain 3 0.2 0.2 no signal
1067 White Blood Cell Count Decreased 26 0.2 0.2 no signal
1068 Amenorrhoea 4 0.2 0.2 no signal
1069 Oesophageal Carcinoma 7 0.2 0.2 no signal
1070 Therapy Interrupted 16 0.2 0.2 no signal
1071 Application Site Erythema 6 0.2 0.2 no signal
1072 Product Availability Issue 5 0.2 0.2 no signal
1073 Pain Of Skin 6 0.2 0.2 no signal
1074 Dyskinesia 9 0.2 0.2 no signal
1075 Incorrect Route Of Drug Administration 8 0.2 0.2 no signal
1076 Tardive Dyskinesia 6 0.1 0.1 no signal
1077 Incorrect Drug Administration Duration 6 0.1 0.1 no signal
1078 Disease Recurrence 10 0.1 0.1 no signal
1079 Dystonia 4 0.1 0.1 no signal
1080 Completed Suicide 17 0.1 0.1 no signal
1081 Injection Site Warmth 4 0.1 0.1 no signal
1082 Multiple Sclerosis 9 0.1 0.1 no signal
1083 Interstitial Lung Disease 9 0.1 0.1 no signal
1084 Overdose 40 0.1 0.1 no signal
1085 Application Site Pruritus 4 0.1 0.1 no signal
1086 Disease Progression 20 0.1 0.1 no signal
1087 Skin Burning Sensation 12 0.1 0.1 no signal
1088 Malignant Neoplasm Progression 17 0.1 0.1 no signal
1089 Product Administered At Inappropriate Site 3 0.1 0.1 no signal
1090 Product Complaint 4 0.1 0.1 no signal
1091 Aggression 8 0.1 0.1 no signal
1092 Breast Cancer 15 0.1 0.1 no signal
1093 Abortion Spontaneous 6 0.1 0.1 no signal
1094 Exposure During Pregnancy 9 0.1 0.1 no signal
1095 Thrombocytopenia 16 0.1 0.1 no signal
1096 Intentional Drug Misuse 3 0.1 0.1 no signal
1097 Product Adhesion Issue 5 0.1 0.1 no signal
1098 Dermatitis Atopic 7 0.1 0.1 no signal
1099 No Adverse Event 24 0.1 0.1 no signal
1100 Accidental Exposure To Product 13 0.1 0.1 no signal
1101 Multiple Sclerosis Relapse 8 0.1 0.1 no signal
1102 Breast Cancer Female 3 0.1 0.1 no signal
1103 Foetal Exposure During Pregnancy 9 0.1 0.1 no signal
1104 Gynaecomastia 3 0.1 0.1 no signal
1105 Device Difficult To Use 6 0.1 0.1 no signal
1106 Neutropenia 12 0.1 0.1 no signal
1107 Drug Withdrawal Syndrome 7 0.1 0.1 no signal
1108 Drug Dose Omission By Device 4 0.0 0.0 no signal
1109 Drug Dependence 8 0.0 0.0 no signal