OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Canakinumab

1,006 flagged reaction(s) · 40,722 total co-reports · max PRR 15,382.6
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Familial Cold Autoinflammatory Syndrome 16 15,382.6 15,405.5 signal
2 Mevalonate Kinase Deficiency 6 11,537.0 11,543.4 signal
3 Muckle-wells Syndrome 39 8,332.3 8,362.6 signal
4 X-linked Lymphoproliferative Syndrome 24 5,127.5 5,139.0 signal
5 Bronchial Atresia 5 4,807.1 4,809.3 signal
6 Actinomycotic Sepsis 17 4,086.0 4,092.5 signal
7 Chronic Infantile Neurological Cutaneous And Articular Syndrome 13 3,571.0 3,575.3 signal
8 Hyper Igd Syndrome 8 2,563.8 2,565.7 signal
9 Cryopyrin Associated Periodic Syndrome 106 2,370.0 2,393.6 signal
10 Tumour Necrosis Factor Receptor-associated Periodic Syndrome 27 1,573.2 1,577.2 signal
11 Familial Mediterranean Fever 81 1,403.1 1,413.8 signal
12 Chemokine Increased 11 1,321.9 1,323.3 signal
13 Serum Amyloid A Protein Increased 53 1,009.0 1,014.0 signal
14 Vascular Cognitive Impairment 5 600.9 601.2 signal
15 Autoinflammatory Disease 45 544.2 546.5 signal
16 Intestinal Sepsis 49 468.7 470.9 signal
17 Short Stature 50 462.2 464.4 signal
18 Familial Amyloidosis 4 427.3 427.5 signal
19 Pericardial Calcification 7 313.0 313.2 signal
20 Periodontal Inflammation 5 291.3 291.5 signal
21 Interleukin Level Increased 60 247.0 248.4 signal
22 Spinal Instability 26 228.3 228.8 signal
23 Herpes Zoster Infection Neurological 16 215.1 215.5 signal
24 Atlantoaxial Instability 10 192.3 192.5 signal
25 Pulmonary Septal Thickening 8 189.9 190.0 signal
26 Vexas Syndrome 8 189.9 190.0 signal
27 Apparent Death 324 189.9 195.7 signal
28 Clubbing 33 170.6 171.1 signal
29 Secondary Amyloidosis 12 168.4 168.6 signal
30 Pneumonia Lipoid 10 160.2 160.4 signal
31 Chronic Recurrent Multifocal Osteomyelitis 8 150.8 150.9 signal
32 Hypertensive Cardiomyopathy 19 140.5 140.8 signal
33 Juvenile Idiopathic Arthritis 154 130.8 132.7 signal
34 Lymph Nodes Scan Abnormal 7 115.0 115.1 signal
35 Epidural Lipomatosis 19 112.4 112.6 signal
36 Hyperferritinaemia 19 93.7 93.8 signal
37 Pleural Adhesion 9 91.6 91.6 signal
38 Muscle Abscess 27 88.3 88.5 signal
39 Congenital Aplasia 12 84.2 84.3 signal
40 Cellulitis Staphylococcal 24 74.3 74.5 signal
41 Haemophagocytic Lymphohistiocytosis 261 73.1 74.8 signal
42 Asteatosis 4 71.2 71.2 signal
43 Joint Arthroplasty 60 67.4 67.8 signal
44 Growth Failure 11 63.9 64.0 signal
45 Steroid Dependence 26 61.5 61.6 signal
46 Focal Nodular Hyperplasia 16 61.0 61.1 signal
47 Growth Retardation 86 58.3 58.8 signal
48 Secondary Adrenocortical Insufficiency 42 56.3 56.5 signal
49 C-reactive Protein Abnormal 165 51.5 52.3 signal
50 Pneumonia Streptococcal 28 51.0 51.1 signal
51 Gastroenteritis Adenovirus 4 50.9 51.0 signal
52 Scarlet Fever 8 50.1 50.1 signal
53 Histiocytosis Haematophagic 74 49.1 49.4 signal
54 Hla Marker Study Positive 4 49.0 49.0 signal
55 Blood Creatine Phosphokinase Decreased 8 47.8 47.8 signal
56 Alveolar Proteinosis 14 47.7 47.8 signal
57 Delayed Puberty 6 47.1 47.1 signal
58 Cushingoid 76 47.0 47.3 signal
59 Red Blood Cell Sedimentation Rate Increased 253 45.5 46.6 signal
60 Terminal State 151 44.9 45.5 signal
61 Red Blood Cell Sedimentation Rate 6 42.4 42.4 signal
62 Extravasation Blood 5 42.4 42.4 signal
63 Pulmonary Thrombosis 210 38.2 38.9 signal
64 Cystitis Viral 7 36.5 36.5 signal
65 Upper Respiratory Tract Inflammation 22 36.2 36.3 signal
66 Chondrocalcinosis 11 34.6 34.7 signal
67 Inappropriate Schedule Of Drug Administration 1,242 34.1 38.5 signal
68 Spondyloarthropathy 10 33.2 33.2 signal
69 Obstructive Sleep Apnoea Syndrome 22 31.2 31.3 signal
70 Serum Ferritin Increased 81 30.5 30.8 signal
71 Juvenile Arthritis 5 29.8 29.8 signal
72 Hyperplasia 13 28.4 28.4 signal
73 Cor Pulmonale Acute 4 28.3 28.3 signal
74 Joint Ankylosis 8 27.6 27.6 signal
75 Superinfection Bacterial 11 27.5 27.5 signal
76 Amyloidosis 24 27.5 27.5 signal
77 Diverticulitis 381 27.2 28.2 signal
78 Cutaneous Symptom 9 26.6 26.6 signal
79 Steatohepatitis 7 25.7 25.7 signal
80 Wrist Deformity 8 25.5 25.5 signal
81 Varicella Zoster Virus Infection 25 23.9 23.9 signal
82 Obliterative Bronchiolitis 16 23.8 23.8 signal
83 Activated Partial Thromboplastin Time Shortened 5 23.4 23.4 signal
84 Pneumonia Mycoplasmal 9 22.3 22.3 signal
85 Lymphangitis 9 22.2 22.2 signal
86 Red Blood Cell Sedimentation Rate Abnormal 25 21.2 21.2 signal
87 Adenoidal Hypertrophy 4 20.9 20.9 signal
88 Infection Reactivation 12 20.6 20.7 signal
89 Hepatosplenomegaly 26 19.8 19.9 signal
90 Meningitis Listeria 5 19.2 19.2 signal
91 Graft Versus Host Disease In Gastrointestinal Tract 20 18.5 18.5 signal
92 Sputum Abnormal 6 18.1 18.1 signal
93 Concomitant Disease Aggravated 56 17.8 17.9 signal
94 Product Temperature Excursion Issue 43 17.8 17.9 signal
95 Ileal Ulcer 9 17.6 17.6 signal
96 Rotavirus Infection 5 17.3 17.3 signal
97 Epstein-barr Virus Infection Reactivation 11 17.1 17.1 signal
98 C-reactive Protein Increased 316 17.1 17.6 signal
99 Hypergammaglobulinaemia 4 16.4 16.4 signal
100 Inflammatory Marker Increased 40 16.0 16.1 signal
101 Skin Oedema 8 15.6 15.6 signal
102 Tonsillitis 41 15.5 15.5 signal
103 Vitiligo 18 15.3 15.4 signal
104 Small Intestine Ulcer 5 15.0 15.1 signal
105 Concomitant Disease Progression 15 14.9 14.9 signal
106 Intestinal Dilatation 10 14.8 14.8 signal
107 Gene Mutation 15 14.8 14.8 signal
108 Stent Placement 60 14.6 14.7 signal
109 Impetigo 11 14.6 14.6 signal
110 Product Supply Issue 52 14.5 14.5 signal
111 Epiglottitis 4 14.4 14.4 signal
112 Pulmonary Veno-occlusive Disease 5 14.1 14.1 signal
113 Blood Fibrinogen Decreased 8 14.0 14.0 signal
114 Photosensitivity Reaction 116 13.8 14.0 signal
115 Symptom Recurrence 41 13.7 13.8 signal
116 Otitis Media 23 13.6 13.7 signal
117 Otitis Media Acute 5 13.3 13.3 signal
118 Anaemia Of Chronic Disease 6 13.0 13.0 signal
119 Cardiac Amyloidosis 7 12.6 12.6 signal
120 Pulmonary Function Test Abnormal 10 12.6 12.6 signal
121 Hand-foot-and-mouth Disease 5 12.2 12.2 signal
122 Dactylitis 6 12.0 12.0 signal
123 Autoimmune Thyroiditis 23 12.0 12.0 signal
124 Pneumonia Viral 19 11.7 11.7 signal
125 Nephrocalcinosis 7 11.6 11.6 signal
126 Graft Versus Host Disease In Skin 13 11.6 11.6 signal
127 Varicella 14 11.4 11.4 signal
128 Acute Graft Versus Host Disease In Skin 16 11.4 11.4 signal
129 Infectious Mononucleosis 13 11.3 11.3 signal
130 Non-alcoholic Steatohepatitis 6 11.2 11.2 signal
131 Osteoporotic Fracture 11 11.2 11.2 signal
132 Arthritis Infective 26 11.0 11.0 signal
133 Rhinovirus Infection 21 10.8 10.8 signal
134 Bronchial Wall Thickening 4 10.8 10.8 signal
135 Inappropriate Schedule Of Product Administration 960 10.6 11.6 signal
136 Bacterial Sepsis 17 10.2 10.2 signal
137 Deep Vein Thrombosis 336 10.1 10.4 signal
138 Faecal Calprotectin Increased 16 10.1 10.1 signal
139 Lung Opacity 13 9.9 9.9 signal
140 Pharyngitis Streptococcal 54 9.8 9.8 signal
141 Interstitial Lung Disease 238 9.6 9.8 signal
142 Spinal Stenosis 20 9.6 9.6 signal
143 Gastric Dilatation 8 9.4 9.4 signal
144 Tonsillar Hypertrophy 8 9.4 9.4 signal
145 Polyarthritis 25 9.3 9.3 signal
146 Vein Disorder 24 9.3 9.3 signal
147 Knee Deformity 7 9.2 9.2 signal
148 Immune Thrombocytopenia 21 9.2 9.2 signal
149 Enterovirus Infection 4 9.2 9.2 signal
150 Infection Susceptibility Increased 10 9.0 9.0 signal
151 Pseudomonal Sepsis 8 8.9 8.9 signal
152 Blood Albumin Increased 4 8.8 8.8 signal
153 Systemic Mycosis 5 8.4 8.4 signal
154 Bone Cyst 4 8.3 8.3 signal
155 Normal Newborn 23 8.3 8.3 signal
156 Gastroenteritis 61 8.2 8.2 signal
157 Adrenal Disorder 8 8.2 8.2 signal
158 Pyrexia 1,431 8.1 9.2 signal
159 Haemophilus Infection 4 8.0 8.0 signal
160 Enteritis Infectious 7 8.0 8.0 signal
161 Blood Immunoglobulin G Increased 5 8.0 8.0 signal
162 Contraindicated Product Administered 123 8.0 8.1 signal
163 Pulmonary Embolism 389 8.0 8.2 signal
164 Joint Swelling 490 8.0 8.3 signal
165 Type Iv Hypersensitivity Reaction 11 7.9 7.9 signal
166 Epstein-barr Virus Infection 25 7.9 7.9 signal
167 Butterfly Rash 4 7.8 7.8 signal
168 Beta Haemolytic Streptococcal Infection 5 7.8 7.8 signal
169 Hepatic Steatosis 74 7.8 7.8 signal
170 Inflammatory Bowel Disease 39 7.8 7.8 signal
171 Streptococcal Infection 22 7.7 7.7 signal
172 Incorrect Dose Administered By Product 6 7.7 7.7 signal
173 Pyoderma Gangrenosum 14 7.7 7.7 signal
174 Allergy To Animal 4 7.5 7.5 signal
175 Joint Effusion 26 7.3 7.4 signal
176 Subcutaneous Abscess 18 7.3 7.3 signal
177 Lymphadenitis 9 7.3 7.3 signal
178 Wrong Dose 9 7.3 7.3 signal
179 Hand Fracture 26 7.2 7.2 signal
180 Discharge 5 7.2 7.2 signal
181 Nasal Discharge Discolouration 5 7.1 7.1 signal
182 Physical Deconditioning 9 7.0 7.0 signal
183 Oesophageal Candidiasis 14 6.9 6.9 signal
184 Osteopenia 54 6.9 7.0 signal
185 Kidney Fibrosis 6 6.8 6.8 signal
186 Groin Abscess 4 6.7 6.7 signal
187 Bone Erosion 12 6.6 6.6 signal
188 Sars-cov-2 Test Positive 45 6.6 6.6 signal
189 Crepitations 10 6.5 6.5 signal
190 Sinus Node Dysfunction 6 6.4 6.4 signal
191 Arthropod Bite 24 6.4 6.4 signal
192 Blood Lactate Dehydrogenase Increased 52 6.4 6.4 signal
193 Hepatomegaly 32 6.3 6.4 signal
194 Enterocolitis 18 6.2 6.2 signal
195 Inflammation 161 6.1 6.2 signal
196 Herpes Zoster 178 6.0 6.1 signal
197 Cytomegalovirus Colitis 7 6.0 6.0 signal
198 Deafness Neurosensory 10 6.0 6.0 signal
199 Lymphadenopathy 108 6.0 6.0 signal
200 Cytomegalovirus Infection Reactivation 13 6.0 6.0 signal
201 Exposure Via Father 4 5.9 5.9 signal
202 Knee Arthroplasty 63 5.9 5.9 signal
203 Atypical Pneumonia 9 5.9 5.9 signal
204 Clostridium Difficile Colitis 32 5.9 5.9 signal
205 Drug Reaction With Eosinophilia And Systemic Symptoms 75 5.7 5.8 signal
206 Hypertransaminasaemia 20 5.7 5.7 signal
207 Body Temperature Increased 60 5.7 5.8 signal
208 Failure To Thrive 15 5.6 5.6 signal
209 Condition Aggravated 867 5.6 6.0 signal
210 Atypical Mycobacterial Infection 4 5.6 5.6 signal
211 Respiratory Symptom 8 5.6 5.6 signal
212 Wound Infection 31 5.6 5.6 signal
213 Thrombosis 230 5.6 5.7 signal
214 Neutrophil Count Abnormal 8 5.5 5.5 signal
215 Renal Failure 378 5.5 5.7 signal
216 Illness 283 5.5 5.6 signal
217 Fibrin D Dimer Increased 10 5.5 5.5 signal
218 Cutaneous Vasculitis 10 5.5 5.5 signal
219 Pharyngeal Erythema 6 5.4 5.4 signal
220 Sepsis 309 5.4 5.5 signal
221 Skin Papilloma 11 5.4 5.4 signal
222 Conjunctivitis Allergic 4 5.3 5.3 signal
223 Viral Infection 90 5.3 5.3 signal
224 Intracranial Pressure Increased 15 5.3 5.3 signal
225 Bk Virus Infection 9 5.2 5.3 signal
226 Chronic Gastritis 6 5.2 5.2 signal
227 Pleurisy 16 5.2 5.2 signal
228 Idiopathic Intracranial Hypertension 6 5.2 5.2 signal
229 Mastitis 5 5.2 5.2 signal
230 Pharyngitis 33 5.2 5.2 signal
231 Splenomegaly 31 5.2 5.2 signal
232 Astigmatism 4 5.2 5.2 signal
233 Ear Infection 69 5.1 5.1 signal
234 Arthropathy 145 5.1 5.1 signal
235 Coronavirus Infection 17 5.0 5.0 signal
236 Paronychia 11 5.0 5.0 signal
237 Macule 7 4.9 4.9 signal
238 Stomatitis 153 4.9 5.0 signal
239 Multi-organ Disorder 5 4.9 4.9 signal
240 Cellulitis 125 4.8 4.9 signal
241 Decreased Immune Responsiveness 24 4.8 4.8 signal
242 Papilloedema 11 4.7 4.7 signal
243 Gastrointestinal Perforation 10 4.7 4.7 signal
244 Pneumocystis Jirovecii Pneumonia 24 4.7 4.7 signal
245 Alanine Aminotransferase Abnormal 5 4.7 4.7 signal
246 Arthritis 185 4.6 4.6 signal
247 Upper Respiratory Tract Infection 108 4.6 4.6 signal
248 Skin Infection 26 4.5 4.6 signal
249 Acute Sinusitis 4 4.5 4.5 signal
250 Depression Suicidal 8 4.5 4.5 signal
251 Meningitis 15 4.4 4.4 signal
252 Incorrect Dose Administered 504 4.4 4.5 signal
253 Pulmonary Hypertension 46 4.3 4.3 signal
254 Osteoporosis 89 4.2 4.2 signal
255 Rhinorrhoea 139 4.2 4.3 signal
256 Synovial Cyst 10 4.2 4.2 signal
257 Breakthrough Pain 5 4.2 4.2 signal
258 Rhinitis 17 4.1 4.1 signal
259 Adenovirus Infection 6 4.1 4.1 signal
260 Anxiety Disorder 7 4.1 4.1 signal
261 Panniculitis 5 4.0 4.0 signal
262 Anal Abscess 11 4.0 4.0 signal
263 Influenza 229 4.0 4.1 signal
264 Hepatic Cytolysis 25 4.0 4.0 signal
265 Glomerulonephritis 5 4.0 4.0 signal
266 Pericarditis 34 4.0 4.0 signal
267 Lymphocyte Count Decreased 36 4.0 4.0 signal
268 Product Distribution Issue 18 4.0 4.0 signal
269 Body Temperature Decreased 20 3.9 3.9 signal
270 Cytopenia 24 3.9 3.9 signal
271 Empyema 4 3.9 3.9 signal
272 Therapy Partial Responder 30 3.9 3.9 signal
273 Loss Of Therapeutic Response 6 3.9 3.9 signal
274 Immunosuppression 17 3.8 3.8 signal
275 Gastroenteritis Viral 35 3.8 3.8 signal
276 Injection Site Extravasation 24 3.8 3.8 signal
277 Lung Disorder 94 3.7 3.8 signal
278 Staphylococcal Infection 63 3.7 3.7 signal
279 Sarcoidosis 9 3.7 3.7 signal
280 Maternal Exposure Timing Unspecified 7 3.7 3.7 signal
281 Viral Upper Respiratory Tract Infection 9 3.7 3.7 signal
282 Mouth Ulceration 39 3.6 3.6 signal
283 Transaminases Increased 41 3.6 3.6 signal
284 Drug Ineffective For Unapproved Indication 102 3.6 3.6 signal
285 Drug Resistance 47 3.6 3.6 signal
286 Intentional Product Use Issue 159 3.5 3.6 signal
287 Urticaria 300 3.5 3.6 signal
288 Disease Recurrence 86 3.5 3.5 signal
289 Suspected Covid-19 6 3.5 3.5 signal
290 Conjunctivitis 33 3.5 3.5 signal
291 Meningitis Aseptic 8 3.5 3.5 signal
292 Proctitis 5 3.5 3.5 signal
293 Postoperative Wound Infection 12 3.5 3.5 signal
294 Covid-19 310 3.4 3.5 signal
295 Ocular Discomfort 19 3.4 3.4 signal
296 Nasal Congestion 102 3.4 3.4 signal
297 Hidradenitis 15 3.4 3.4 signal
298 Uveitis 23 3.3 3.3 signal
299 Eye Inflammation 16 3.3 3.3 signal
300 Aphthous Ulcer 13 3.3 3.3 signal
301 Foot Fracture 32 3.3 3.3 signal
302 Conjunctival Hyperaemia 6 3.3 3.3 signal
303 Angina Unstable 11 3.3 3.3 signal
304 Bone Marrow Disorder 5 3.2 3.2 signal
305 Malaise 727 3.2 3.4 signal
306 Autism Spectrum Disorder 9 3.2 3.2 signal
307 Drug Intolerance 158 3.2 3.2 signal
308 Cardiac Dysfunction 6 3.2 3.2 signal
309 Quality Of Life Decreased 22 3.2 3.2 signal
310 Abscess 26 3.2 3.2 signal
311 Multiple-drug Resistance 5 3.2 3.2 signal
312 Spinal Fracture 32 3.1 3.1 signal
313 Erysipelas 8 3.1 3.1 signal
314 Blood Pressure Systolic Increased 31 3.1 3.1 signal
315 Oropharyngeal Pain 146 3.1 3.1 signal
316 Rhinitis Allergic 7 3.1 3.1 signal
317 Haemoglobin Decreased 162 3.1 3.1 signal
318 Incorrect Route Of Product Administration 26 3.0 3.0 signal
319 Near Death Experience 5 3.0 3.0 signal
320 Pain 941 3.0 3.2 signal
321 Wound Secretion 6 3.0 3.0 signal
322 Lyme Disease 5 2.9 2.9 signal
323 Skin Lesion 41 2.9 2.9 signal
324 Product Leakage 8 2.9 2.9 signal
325 Uterine Leiomyoma 11 2.9 2.9 signal
326 Deafness 39 2.9 2.9 signal
327 Eosinophilia 26 2.9 2.9 signal
328 Tuberculosis 19 2.9 2.9 signal
329 Spinal Disorder 14 2.9 2.9 signal
330 Arthralgia 611 2.9 3.0 signal
331 Hydronephrosis 11 2.9 2.9 signal
332 Therapy Non-responder 65 2.8 2.9 signal
333 Infection 209 2.8 2.9 signal
334 Neuralgia 35 2.8 2.8 signal
335 Obesity 23 2.8 2.8 signal
336 Papule 10 2.8 2.8 signal
337 Acute Coronary Syndrome 12 2.8 2.8 signal
338 Immunodeficiency 21 2.8 2.8 signal
339 Respiratory Tract Infection 37 2.8 2.8 signal
340 Breath Sounds Abnormal 7 2.8 2.8 signal
341 Immune-mediated Enterocolitis 5 2.8 2.8 signal
342 Pseudomonas Infection 12 2.8 2.8 signal
343 Enteritis 9 2.8 2.8 signal
344 Neutrophilia 8 2.7 2.8 signal
345 Hypogammaglobulinaemia 9 2.7 2.7 signal
346 Appendicitis 13 2.7 2.7 signal
347 Ear Pain 27 2.7 2.7 signal
348 Drug Administered To Patient Of Inappropriate Age 10 2.7 2.7 signal
349 Tooth Abscess 14 2.7 2.7 signal
350 Product Use In Unapproved Indication 332 2.7 2.7 signal
351 Autoimmune Disorder 13 2.6 2.7 signal
352 Scratch 14 2.6 2.6 signal
353 Ileus Paralytic 6 2.6 2.6 signal
354 Adrenal Insufficiency 16 2.6 2.6 signal
355 Injection Site Vesicles 8 2.6 2.6 signal
356 Troponin Increased 10 2.6 2.6 signal
357 Eosinophil Count Increased 11 2.6 2.6 signal
358 Nasopharyngitis 244 2.6 2.6 signal
359 Skin Plaque 11 2.5 2.5 signal
360 Duodenitis 4 2.5 2.5 no signal
361 Rash 564 2.5 2.6 signal
362 Bronchopulmonary Aspergillosis 10 2.5 2.5 signal
363 Haemolysis 10 2.5 2.5 signal
364 Therapeutic Response Shortened 41 2.5 2.5 signal
365 Infusion Site Extravasation 8 2.5 2.5 signal
366 Product Storage Error 111 2.5 2.5 signal
367 Localised Infection 31 2.5 2.5 signal
368 Pyelonephritis 11 2.5 2.5 signal
369 Fracture 24 2.5 2.5 signal
370 Brain Oedema 16 2.5 2.5 signal
371 Syringe Issue 22 2.4 2.5 signal
372 Product Availability Issue 28 2.4 2.4 signal
373 Hepatitis Acute 8 2.4 2.4 signal
374 Respiratory Disorder 37 2.4 2.4 signal
375 Wound 34 2.4 2.4 signal
376 Abdominal Pain 284 2.4 2.4 signal
377 Anaphylactoid Reaction 5 2.4 2.4 no signal
378 Hyperuricaemia 5 2.4 2.4 no signal
379 Ill-defined Disorder 74 2.4 2.4 signal
380 Osteomyelitis 22 2.4 2.4 signal
381 Fluid Intake Reduced 6 2.4 2.4 no signal
382 Injection Site Inflammation 6 2.4 2.4 no signal
383 Demyelination 5 2.4 2.4 no signal
384 Staphylococcal Sepsis 6 2.4 2.4 no signal
385 Pneumonia Bacterial 11 2.3 2.4 signal
386 Attention Deficit Hyperactivity Disorder 5 2.3 2.3 no signal
387 Skin Warm 7 2.3 2.3 signal
388 Product Administration Error 24 2.3 2.3 signal
389 Bronchiectasis 8 2.3 2.3 signal
390 Cough 334 2.3 2.4 signal
391 Atrial Septal Defect 10 2.3 2.3 signal
392 Needle Issue 34 2.3 2.3 signal
393 Acute Respiratory Distress Syndrome 21 2.3 2.3 signal
394 Activated Partial Thromboplastin Time Prolonged 6 2.3 2.3 no signal
395 Escherichia Urinary Tract Infection 5 2.3 2.3 no signal
396 Abscess Limb 5 2.3 2.3 no signal
397 Drug Dispensing Error 18 2.3 2.3 signal
398 Posterior Reversible Encephalopathy Syndrome 11 2.3 2.3 signal
399 Respiratory Syncytial Virus Infection 10 2.3 2.3 signal
400 Sensitivity To Weather Change 6 2.2 2.2 no signal
401 Skin Disorder 38 2.2 2.2 signal
402 Product Prescribing Error 27 2.2 2.2 signal
403 Lymphopenia 16 2.2 2.2 signal
404 Bronchiolitis 4 2.2 2.2 no signal
405 Gamma-glutamyltransferase Increased 25 2.2 2.2 signal
406 Food Poisoning 6 2.2 2.2 no signal
407 Liver Function Test Increased 24 2.2 2.2 signal
408 Blood Disorder 9 2.2 2.2 signal
409 Gastrointestinal Infection 10 2.2 2.2 signal
410 Renal Tubular Necrosis 11 2.2 2.2 signal
411 Gingivitis 6 2.2 2.2 no signal
412 Iron Deficiency Anaemia 10 2.1 2.1 signal
413 Pericardial Effusion 25 2.1 2.1 signal
414 Ear Disorder 5 2.1 2.1 no signal
415 Leukopenia 54 2.1 2.1 signal
416 Bacterial Infection 20 2.1 2.1 signal
417 Intercepted Medication Error 5 2.1 2.1 no signal
418 Bronchitis 79 2.1 2.1 signal
419 Hepatic Enzyme Increased 72 2.1 2.1 signal
420 Skin Swelling 9 2.1 2.1 no signal
421 Hepatic Necrosis 4 2.1 2.1 no signal
422 Injection Site Rash 32 2.1 2.1 signal
423 Tenderness 11 2.1 2.1 signal
424 Cataract 62 2.0 2.0 signal
425 Joint Dislocation 11 2.0 2.0 signal
426 Rales 6 2.0 2.0 no signal
427 Pneumonia 333 2.0 2.0 signal
428 Hypertriglyceridaemia 6 2.0 2.0 no signal
429 Glucose Tolerance Impaired 6 2.0 2.0 no signal
430 Incorrect Dosage Administered 5 2.0 2.0 no signal
431 Aspartate Aminotransferase Increased 54 2.0 2.0 no signal
432 Odynophagia 6 2.0 2.0 no signal
433 Ligament Sprain 10 2.0 2.0 no signal
434 Cerebral Atrophy 4 2.0 2.0 no signal
435 Product Administered To Patient Of Inappropriate Age 6 1.9 1.9 no signal
436 Alanine Aminotransferase Increased 61 1.9 1.9 no signal
437 Arthritis Bacterial 4 1.9 1.9 no signal
438 Hepatitis 25 1.9 1.9 no signal
439 Cardiomegaly 12 1.9 1.9 no signal
440 Product Dispensing Error 21 1.9 1.9 no signal
441 Hyperpyrexia 4 1.9 1.9 no signal
442 Maternal Exposure During Pregnancy 85 1.9 1.9 no signal
443 Hypokinesia 14 1.9 1.9 no signal
444 Productive Cough 45 1.9 1.9 no signal
445 Hordeolum 4 1.9 1.9 no signal
446 Myocardial Infarction 166 1.8 1.9 no signal
447 Feeling Abnormal 227 1.8 1.9 no signal
448 Rash Erythematous 44 1.8 1.8 no signal
449 Neck Pain 52 1.8 1.8 no signal
450 Thrombotic Microangiopathy 9 1.8 1.8 no signal
451 Drug Ineffective 1,212 1.8 1.9 no signal
452 Therapeutic Product Effect Incomplete 65 1.8 1.8 no signal
453 Immune System Disorder 12 1.8 1.8 no signal
454 Deafness Unilateral 5 1.8 1.8 no signal
455 Abdominal Abscess 4 1.8 1.8 no signal
456 Gastrointestinal Disorder 80 1.8 1.8 no signal
457 Dental Caries 10 1.8 1.8 no signal
458 Blood Creatine Increased 4 1.8 1.8 no signal
459 Nephropathy Toxic 10 1.8 1.8 no signal
460 Haematochezia 49 1.7 1.7 no signal
461 Haemoglobin Increased 4 1.7 1.7 no signal
462 Intestinal Haemorrhage 5 1.7 1.7 no signal
463 General Physical Condition Abnormal 6 1.7 1.7 no signal
464 White Blood Cell Count Increased 34 1.7 1.7 no signal
465 Neutrophil Count Increased 9 1.7 1.7 no signal
466 Disease Complication 4 1.7 1.7 no signal
467 Chills 102 1.7 1.7 no signal
468 Autoimmune Hepatitis 6 1.7 1.7 no signal
469 Treatment Failure 71 1.7 1.7 no signal
470 Large Intestine Perforation 6 1.7 1.7 no signal
471 Blood Pressure Diastolic Increased 4 1.7 1.7 no signal
472 Fear Of Injection 6 1.7 1.7 no signal
473 Ocular Hyperaemia 40 1.7 1.7 no signal
474 Escherichia Infection 7 1.7 1.7 no signal
475 Flank Pain 8 1.7 1.7 no signal
476 Pallor 23 1.6 1.6 no signal
477 Cytomegalovirus Infection 14 1.6 1.6 no signal
478 Impaired Quality Of Life 12 1.6 1.6 no signal
479 Glaucoma 16 1.6 1.6 no signal
480 Multiple Organ Dysfunction Syndrome 23 1.6 1.6 no signal
481 Off Label Use 715 1.6 1.6 no signal
482 Colitis 31 1.6 1.6 no signal
483 Heart Rate Decreased 29 1.6 1.6 no signal
484 Myalgia 139 1.6 1.6 no signal
485 Generalised Oedema 10 1.6 1.6 no signal
486 Hepatotoxicity 18 1.6 1.6 no signal
487 Secretion Discharge 10 1.6 1.6 no signal
488 Night Sweats 26 1.6 1.6 no signal
489 Scoliosis 5 1.6 1.6 no signal
490 Hepatic Enzyme Abnormal 4 1.6 1.6 no signal
491 Hepatic Cirrhosis 15 1.6 1.6 no signal
492 Intestinal Perforation 9 1.6 1.6 no signal
493 Hypomagnesaemia 11 1.5 1.5 no signal
494 Purpura 7 1.5 1.5 no signal
495 Respiratory Rate Increased 7 1.5 1.5 no signal
496 Facial Pain 7 1.5 1.5 no signal
497 Coagulopathy 13 1.5 1.5 no signal
498 Skin Reaction 11 1.5 1.5 no signal
499 Pneumonitis 21 1.5 1.5 no signal
500 Concussion 6 1.5 1.5 no signal
501 Hepatocellular Injury 11 1.5 1.5 no signal
502 Peritonitis 16 1.5 1.5 no signal
503 Vasculitis 9 1.5 1.5 no signal
504 Herpes Simplex 5 1.5 1.5 no signal
505 Melaena 17 1.5 1.5 no signal
506 Platelet Count Increased 10 1.5 1.5 no signal
507 Furuncle 6 1.5 1.5 no signal
508 Cholecystitis 9 1.5 1.5 no signal
509 Covid-19 Pneumonia 9 1.5 1.5 no signal
510 Low Birth Weight Baby 6 1.5 1.5 no signal
511 Hypertension 160 1.5 1.5 no signal
512 Gingival Pain 6 1.5 1.5 no signal
513 Swelling 70 1.5 1.5 no signal
514 Sinusitis 77 1.5 1.5 no signal
515 Joint Injury 16 1.5 1.5 no signal
516 Decreased Activity 8 1.5 1.5 no signal
517 Liver Disorder 33 1.5 1.5 no signal
518 Hypoacusis 32 1.5 1.5 no signal
519 Stress 53 1.4 1.4 no signal
520 Thrombocytopenia 82 1.4 1.4 no signal
521 Drug Hypersensitivity 142 1.4 1.4 no signal
522 Pharyngeal Swelling 7 1.4 1.4 no signal
523 Gait Inability 24 1.4 1.4 no signal
524 Oral Herpes 14 1.4 1.4 no signal
525 Aphonia 10 1.4 1.4 no signal
526 Ascites 21 1.4 1.4 no signal
527 Mobility Decreased 51 1.4 1.4 no signal
528 Incorrect Dose Administered By Device 18 1.4 1.4 no signal
529 Fluid Retention 36 1.4 1.4 no signal
530 Musculoskeletal Stiffness 62 1.4 1.4 no signal
531 Status Epilepticus 8 1.4 1.4 no signal
532 Headache 441 1.4 1.4 no signal
533 Injection Site Reaction 48 1.4 1.4 no signal
534 Hypersomnia 20 1.4 1.4 no signal
535 Weight Increased 155 1.4 1.4 no signal
536 Faeces Soft 5 1.3 1.3 no signal
537 Nail Disorder 6 1.3 1.3 no signal
538 Hypothermia 7 1.3 1.3 no signal
539 Hyperventilation 4 1.3 1.3 no signal
540 Proteinuria 13 1.3 1.3 no signal
541 Rash Pruritic 37 1.3 1.3 no signal
542 Gastritis 18 1.3 1.3 no signal
543 Tooth Infection 9 1.3 1.3 no signal
544 Bacteraemia 8 1.3 1.3 no signal
545 Folliculitis 7 1.3 1.3 no signal
546 Incorrect Product Storage 9 1.3 1.3 no signal
547 Hepatic Function Abnormal 25 1.3 1.3 no signal
548 Pain In Extremity 199 1.3 1.3 no signal
549 Anaphylactic Reaction 37 1.3 1.3 no signal
550 Erythema 138 1.3 1.3 no signal
551 Oropharyngeal Discomfort 6 1.3 1.3 no signal
552 Septic Shock 29 1.3 1.3 no signal
553 Pulmonary Oedema 30 1.3 1.3 no signal
554 Limb Injury 18 1.3 1.3 no signal
555 Therapeutic Response Decreased 40 1.3 1.3 no signal
556 Chest Pain 123 1.3 1.3 no signal
557 Kidney Infection 13 1.3 1.3 no signal
558 Musculoskeletal Pain 35 1.3 1.3 no signal
559 Disease Progression 78 1.3 1.3 no signal
560 Hyperthermia 5 1.3 1.3 no signal
561 Hypothyroidism 21 1.3 1.3 no signal
562 Candida Infection 11 1.3 1.3 no signal
563 Hypoalbuminaemia 5 1.3 1.3 no signal
564 Urinary Tract Infection 111 1.3 1.3 no signal
565 Retinal Detachment 6 1.3 1.3 no signal
566 Mucosal Inflammation 17 1.3 1.3 no signal
567 Feeding Disorder 13 1.3 1.3 no signal
568 Vomiting 305 1.3 1.3 no signal
569 Agranulocytosis 12 1.3 1.3 no signal
570 Joint Stiffness 17 1.3 1.3 no signal
571 Swelling Face 42 1.3 1.3 no signal
572 Laryngitis 7 1.3 1.3 no signal
573 Blepharospasm 4 1.3 1.3 no signal
574 Gastrointestinal Inflammation 5 1.3 1.3 no signal
575 Renal Disorder 30 1.3 1.3 no signal
576 Mass 9 1.3 1.3 no signal
577 Diarrhoea Haemorrhagic 6 1.2 1.2 no signal
578 Gastrointestinal Pain 7 1.2 1.2 no signal
579 Sputum Discoloured 6 1.2 1.2 no signal
580 Tachycardia 56 1.2 1.2 no signal
581 Haemoglobin Abnormal 4 1.2 1.2 no signal
582 Blood Triglycerides Increased 11 1.2 1.2 no signal
583 Product Use Issue 116 1.2 1.2 no signal
584 Prescribed Overdose 12 1.2 1.2 no signal
585 Atelectasis 6 1.2 1.2 no signal
586 Pulmonary Arterial Hypertension 9 1.2 1.2 no signal
587 Neutrophil Count Decreased 25 1.2 1.2 no signal
588 Post Procedural Infection 5 1.2 1.2 no signal
589 Vitamin D Deficiency 6 1.2 1.2 no signal
590 Product Dose Omission Issue 175 1.2 1.2 no signal
591 Bone Pain 36 1.2 1.2 no signal
592 Nodule 8 1.2 1.2 no signal
593 Drug Administration Error 19 1.2 1.2 no signal
594 Rheumatoid Arthritis 69 1.2 1.2 no signal
595 Lethargy 35 1.2 1.2 no signal
596 Leukocytosis 11 1.2 1.2 no signal
597 Vertigo 37 1.2 1.2 no signal
598 Crying 22 1.2 1.2 no signal
599 Blood Pressure Decreased 40 1.2 1.2 no signal
600 Cardiac Failure Acute 4 1.2 1.2 no signal
601 Spinal Pain 7 1.2 1.2 no signal
602 Abdominal Pain Upper 122 1.2 1.2 no signal
603 Incorrect Product Administration Duration 12 1.2 1.2 no signal
604 Sluggishness 6 1.2 1.2 no signal
605 Tachypnoea 8 1.2 1.2 no signal
606 Facial Paralysis 5 1.1 1.1 no signal
607 Respiratory Failure 43 1.1 1.1 no signal
608 Helicobacter Infection 6 1.1 1.1 no signal
609 Temperature Intolerance 6 1.1 1.1 no signal
610 Musculoskeletal Chest Pain 9 1.1 1.1 no signal
611 Lymphoma 9 1.1 1.1 no signal
612 Encephalitis 4 1.1 1.1 no signal
613 Liver Injury 14 1.1 1.1 no signal
614 Muscle Strain 5 1.1 1.1 no signal
615 Oral Pain 13 1.1 1.1 no signal
616 Petechiae 6 1.1 1.1 no signal
617 Eczema 29 1.1 1.1 no signal
618 Acute Respiratory Failure 11 1.1 1.1 no signal
619 Abortion Spontaneous 23 1.1 1.1 no signal
620 White Blood Cell Count Decreased 62 1.1 1.1 no signal
621 Cyanosis 9 1.1 1.1 no signal
622 Influenza Like Illness 47 1.1 1.1 no signal
623 Neutropenia 77 1.1 1.1 no signal
624 Renal Pain 6 1.1 1.1 no signal
625 Groin Pain 5 1.1 1.1 no signal
626 Haemorrhoids 11 1.1 1.1 no signal
627 Blood Alkaline Phosphatase Increased 14 1.1 1.1 no signal
628 Anti-cyclic Citrullinated Peptide Antibody Positive 4 1.1 1.1 no signal
629 Lung Infiltration 5 1.1 1.1 no signal
630 Eating Disorder 12 1.1 1.1 no signal
631 Movement Disorder 18 1.1 1.1 no signal
632 Myositis 5 1.1 1.1 no signal
633 Diverticulum 4 1.1 1.1 no signal
634 Blood Bilirubin Increased 15 1.1 1.1 no signal
635 Device Dislocation 24 1.1 1.1 no signal
636 Impaired Healing 18 1.1 1.1 no signal
637 Blood Creatine Phosphokinase Increased 16 1.1 1.1 no signal
638 Ventricular Tachycardia 9 1.1 1.1 no signal
639 Urosepsis 5 1.1 1.1 no signal
640 Hypoxia 19 1.1 1.1 no signal
641 Malnutrition 6 1.1 1.1 no signal
642 Feeling Cold 15 1.0 1.0 no signal
643 Migraine 51 1.0 1.0 no signal
644 Hypertensive Crisis 6 1.0 1.0 no signal
645 Sneezing 12 1.0 1.0 no signal
646 Injection Site Urticaria 13 1.0 1.0 no signal
647 Blister 30 1.0 1.0 no signal
648 Seizure 61 1.0 1.0 no signal
649 Arteriosclerosis 5 1.0 1.0 no signal
650 Leukaemia 5 1.0 1.0 no signal
651 Food Allergy 4 1.0 1.0 no signal
652 Anaemia 100 1.0 1.0 no signal
653 Back Pain 121 1.0 1.0 no signal
654 Pancytopenia 29 1.0 1.0 no signal
655 Oedema 28 1.0 1.0 no signal
656 Dysuria 19 1.0 1.0 no signal
657 Infusion Related Reaction 34 1.0 1.0 no signal
658 Injection Site Swelling 39 1.0 1.0 no signal
659 Abdominal Pain Lower 13 1.0 1.0 no signal
660 Basal Cell Carcinoma 8 1.0 1.0 no signal
661 Hyperhidrosis 66 1.0 1.0 no signal
662 Affective Disorder 4 1.0 1.0 no signal
663 Faeces Discoloured 11 1.0 1.0 no signal
664 Fatigue 393 1.0 1.0 no signal
665 Therapeutic Product Effect Decreased 22 1.0 1.0 no signal
666 Motor Dysfunction 5 1.0 1.0 no signal
667 Pleural Effusion 30 1.0 1.0 no signal
668 Paralysis 7 0.9 0.9 no signal
669 Lower Respiratory Tract Infection 22 0.9 0.9 no signal
670 Angina Pectoris 14 0.9 0.9 no signal
671 Myelodysplastic Syndrome 7 0.9 0.9 no signal
672 Hyperaesthesia 4 0.9 0.9 no signal
673 Cyst 6 0.9 0.9 no signal
674 Peripheral Swelling 74 0.9 0.9 no signal
675 Psychomotor Hyperactivity 8 0.9 0.9 no signal
676 Weight Fluctuation 5 0.9 0.9 no signal
677 General Physical Health Deterioration 55 0.9 0.9 no signal
678 Gastrointestinal Haemorrhage 40 0.9 0.9 no signal
679 Hypophagia 12 0.9 0.9 no signal
680 Feeling Hot 29 0.9 0.9 no signal
681 Oral Candidiasis 6 0.9 0.9 no signal
682 Product Packaging Quantity Issue 5 0.9 0.9 no signal
683 Skin Discolouration 21 0.9 0.9 no signal
684 Rash Generalised 12 0.9 0.9 no signal
685 Diarrhoea 293 0.9 0.9 no signal
686 Device Related Infection 7 0.9 0.9 no signal
687 Mental Impairment 11 0.9 0.9 no signal
688 Pulmonary Congestion 6 0.9 0.9 no signal
689 Febrile Neutropenia 30 0.9 0.9 no signal
690 Rash Maculo-papular 10 0.9 0.9 no signal
691 Encephalopathy 11 0.9 0.9 no signal
692 Gout 8 0.9 0.9 no signal
693 Rash Papular 10 0.9 0.9 no signal
694 Jaundice 12 0.9 0.9 no signal
695 Dysstasia 13 0.9 0.9 no signal
696 Toothache 8 0.9 0.9 no signal
697 Pneumothorax 7 0.9 0.9 no signal
698 Injection Site Haemorrhage 35 0.9 0.9 no signal
699 Laboratory Test Abnormal 13 0.9 0.9 no signal
700 Ulcer 7 0.9 0.9 no signal
701 Hypersensitivity 81 0.9 0.9 no signal
702 Peripheral Coldness 6 0.8 0.8 no signal
703 Eye Pain 24 0.8 0.8 no signal
704 Respiratory Distress 12 0.8 0.8 no signal
705 Photophobia 8 0.8 0.8 no signal
706 Blood Test Abnormal 6 0.8 0.8 no signal
707 Intestinal Obstruction 16 0.8 0.8 no signal
708 Seasonal Allergy 6 0.8 0.8 no signal
709 Disseminated Intravascular Coagulation 6 0.8 0.8 no signal
710 Gait Disturbance 81 0.8 0.8 no signal
711 Fungal Infection 14 0.8 0.8 no signal
712 Accident 5 0.8 0.8 no signal
713 Pulmonary Fibrosis 8 0.8 0.8 no signal
714 Muscle Rigidity 5 0.8 0.8 no signal
715 Hypercholesterolaemia 4 0.8 0.8 no signal
716 Blood Urea Increased 7 0.8 0.8 no signal
717 Clostridium Difficile Infection 9 0.8 0.8 no signal
718 Medication Error 23 0.8 0.8 no signal
719 Bursitis 5 0.8 0.8 no signal
720 Presyncope 10 0.8 0.8 no signal
721 Weight Decreased 115 0.8 0.8 no signal
722 Drug Effective For Unapproved Indication 12 0.8 0.8 no signal
723 Drug Prescribing Error 8 0.8 0.8 no signal
724 Haematuria 14 0.8 0.8 no signal
725 No Therapeutic Response 5 0.8 0.8 no signal
726 Insurance Issue 6 0.8 0.8 no signal
727 Platelet Count Decreased 43 0.8 0.8 no signal
728 Pulmonary Mass 6 0.8 0.8 no signal
729 Ageusia 10 0.8 0.8 no signal
730 Dyspnoea Exertional 15 0.8 0.8 no signal
731 Hypotonia 4 0.8 0.8 no signal
732 Brain Injury 4 0.8 0.8 no signal
733 Toxic Skin Eruption 4 0.8 0.8 no signal
734 Suicide Attempt 24 0.8 0.8 no signal
735 Injection Site Bruising 31 0.8 0.8 no signal
736 Injection Site Pain 119 0.8 0.8 no signal
737 Blood Count Abnormal 6 0.8 0.8 no signal
738 Injection Site Warmth 8 0.8 0.8 no signal
739 Hyperbilirubinaemia 4 0.8 0.8 no signal
740 Limb Discomfort 12 0.8 0.8 no signal
741 Injection Site Discomfort 4 0.8 0.8 no signal
742 Injection Site Induration 5 0.8 0.8 no signal
743 Haematoma 10 0.7 0.7 no signal
744 Dysmenorrhoea 5 0.7 0.7 no signal
745 Road Traffic Accident 16 0.7 0.7 no signal
746 Pruritus 144 0.7 0.7 no signal
747 Incontinence 4 0.7 0.7 no signal
748 Adverse Reaction 5 0.7 0.7 no signal
749 Mood Swings 12 0.7 0.7 no signal
750 Injection Site Pruritus 25 0.7 0.7 no signal
751 Cystitis 12 0.7 0.7 no signal
752 Premature Delivery 6 0.7 0.7 no signal
753 Heart Rate Increased 37 0.7 0.7 no signal
754 Rash Macular 13 0.7 0.7 no signal
755 Skin Irritation 17 0.7 0.7 no signal
756 Systemic Lupus Erythematosus 13 0.7 0.7 no signal
757 Blood Urine Present 7 0.7 0.7 no signal
758 Sleep Apnoea Syndrome 7 0.7 0.7 no signal
759 Cholelithiasis 12 0.7 0.7 no signal
760 Musculoskeletal Disorder 7 0.7 0.7 no signal
761 Hepatic Failure 11 0.7 0.7 no signal
762 Choking 7 0.7 0.7 no signal
763 Foot Deformity 4 0.7 0.7 no signal
764 Blood Pressure Increased 55 0.7 0.7 no signal
765 Eye Infection 4 0.7 0.7 no signal
766 Wheezing 21 0.7 0.7 no signal
767 Drug Effect Less Than Expected 5 0.7 0.7 no signal
768 Device Leakage 15 0.7 0.7 no signal
769 Contusion 34 0.7 0.7 no signal
770 Blood Pressure Abnormal 7 0.7 0.7 no signal
771 Myocarditis 4 0.7 0.7 no signal
772 Dehydration 47 0.7 0.7 no signal
773 Nervous System Disorder 11 0.7 0.7 no signal
774 Circulatory Collapse 6 0.7 0.7 no signal
775 Haematocrit Decreased 7 0.7 0.7 no signal
776 Cardiogenic Shock 5 0.7 0.7 no signal
777 Nephrolithiasis 16 0.7 0.7 no signal
778 Musculoskeletal Discomfort 6 0.7 0.7 no signal
779 Subdural Haematoma 5 0.7 0.7 no signal
780 Abdominal Discomfort 58 0.7 0.7 no signal
781 Abdominal Distension 36 0.7 0.7 no signal
782 Anosmia 5 0.7 0.7 no signal
783 Brain Fog 5 0.7 0.7 no signal
784 Post Procedural Haemorrhage 4 0.7 0.7 no signal
785 Burning Sensation 24 0.7 0.7 no signal
786 Underdose 25 0.7 0.7 no signal
787 Accidental Exposure To Product 34 0.7 0.7 no signal
788 Asthenia 127 0.7 0.7 no signal
789 Cardiac Failure 27 0.7 0.7 no signal
790 Colon Cancer 5 0.7 0.7 no signal
791 Haemorrhage 35 0.7 0.7 no signal
792 Synovitis 6 0.6 0.6 no signal
793 Osteonecrosis 11 0.6 0.6 no signal
794 Mood Altered 9 0.6 0.6 no signal
795 Discomfort 20 0.6 0.6 no signal
796 Syncope 33 0.6 0.6 no signal
797 Irritable Bowel Syndrome 7 0.6 0.6 no signal
798 Swollen Tongue 10 0.6 0.6 no signal
799 Cardiac Disorder 30 0.6 0.6 no signal
800 Increased Appetite 6 0.6 0.6 no signal
801 Abasia 8 0.6 0.6 no signal
802 Anxiety 91 0.6 0.6 no signal
803 Nausea 250 0.6 0.6 no signal
804 Gastric Ulcer 6 0.6 0.6 no signal
805 Acne 24 0.6 0.6 no signal
806 Colitis Ulcerative 14 0.6 0.6 no signal
807 Pancreatitis Acute 7 0.6 0.6 no signal
808 Anaphylactic Shock 8 0.6 0.6 no signal
809 Mydriasis 4 0.6 0.6 no signal
810 Dyspnoea 175 0.6 0.6 no signal
811 Insomnia 82 0.6 0.6 no signal
812 Epistaxis 23 0.6 0.6 no signal
813 Osteoarthritis 13 0.6 0.6 no signal
814 Generalised Tonic-clonic Seizure 5 0.6 0.6 no signal
815 Speech Disorder 16 0.6 0.6 no signal
816 Eye Disorder 10 0.6 0.6 no signal
817 Decreased Appetite 70 0.6 0.6 no signal
818 Lip Swelling 10 0.6 0.6 no signal
819 Abnormal Behaviour 12 0.6 0.6 no signal
820 Prescribed Underdose 6 0.6 0.6 no signal
821 Upper Limb Fracture 6 0.6 0.6 no signal
822 Injection Site Erythema 37 0.6 0.6 no signal
823 Drug Effect Incomplete 11 0.6 0.6 no signal
824 Full Blood Count Decreased 6 0.6 0.6 no signal
825 Epilepsy 9 0.6 0.6 no signal
826 Acute Hepatic Failure 4 0.6 0.6 no signal
827 Drug-induced Liver Injury 9 0.6 0.6 no signal
828 Palpitations 34 0.6 0.6 no signal
829 Dermatitis 6 0.6 0.6 no signal
830 Central Nervous System Lesion 4 0.6 0.6 no signal
831 Acute Kidney Injury 44 0.6 0.6 no signal
832 Fibromyalgia 7 0.6 0.6 no signal
833 Haemoptysis 8 0.6 0.6 no signal
834 Metastases To Liver 5 0.6 0.6 no signal
835 Head Discomfort 5 0.6 0.6 no signal
836 Cold Sweat 5 0.6 0.6 no signal
837 Foetal Exposure During Pregnancy 23 0.6 0.6 no signal
838 Local Swelling 5 0.6 0.6 no signal
839 Muscular Weakness 32 0.5 0.5 no signal
840 Cerebral Haemorrhage 10 0.5 0.5 no signal
841 Bronchospasm 4 0.5 0.5 no signal
842 Hyperglycaemia 10 0.5 0.5 no signal
843 Dizziness 137 0.5 0.5 no signal
844 Pelvic Pain 5 0.5 0.5 no signal
845 Diabetes Mellitus 21 0.5 0.5 no signal
846 Cardiovascular Disorder 7 0.5 0.5 no signal
847 Angioedema 12 0.5 0.5 no signal
848 End Stage Renal Disease 5 0.5 0.5 no signal
849 Injection Site Mass 10 0.5 0.5 no signal
850 Fluid Overload 4 0.5 0.5 no signal
851 Urinary Incontinence 8 0.5 0.5 no signal
852 Oxygen Saturation Decreased 15 0.5 0.5 no signal
853 Throat Irritation 12 0.5 0.5 no signal
854 Premature Baby 8 0.5 0.5 no signal
855 Pancreatitis 14 0.5 0.5 no signal
856 Rebound Effect 3 0.5 0.5 no signal
857 Cytokine Release Syndrome 5 0.5 0.5 no signal
858 Hyperkalaemia 9 0.5 0.5 no signal
859 Dysphonia 15 0.5 0.5 no signal
860 Gynaecomastia 8 0.5 0.5 no signal
861 Fall 83 0.5 0.5 no signal
862 Constipation 54 0.5 0.5 no signal
863 Irritability 15 0.5 0.5 no signal
864 Incorrect Route Of Drug Administration 9 0.5 0.5 no signal
865 Nervousness 13 0.5 0.5 no signal
866 Pain In Jaw 7 0.5 0.5 no signal
867 Blood Potassium Increased 4 0.5 0.5 no signal
868 Bone Marrow Failure 5 0.5 0.5 no signal
869 Loss Of Consciousness 31 0.5 0.5 no signal
870 Product Dose Omission 16 0.5 0.5 no signal
871 Product Preparation Error 5 0.5 0.5 no signal
872 Pemphigus 3 0.5 0.5 no signal
873 Pneumonia Aspiration 6 0.5 0.5 no signal
874 Skin Exfoliation 20 0.5 0.5 no signal
875 Liver Function Test Abnormal 7 0.5 0.5 no signal
876 Visual Acuity Reduced 8 0.5 0.5 no signal
877 Hot Flush 18 0.5 0.5 no signal
878 Poisoning 3 0.5 0.5 no signal
879 Face Oedema 4 0.5 0.5 no signal
880 Haematemesis 6 0.5 0.5 no signal
881 Chest Discomfort 24 0.5 0.5 no signal
882 Vaginal Haemorrhage 10 0.5 0.5 no signal
883 Lacrimation Increased 7 0.5 0.5 no signal
884 Intraocular Pressure Increased 3 0.5 0.5 no signal
885 Delirium 8 0.5 0.5 no signal
886 Device Use Issue 4 0.5 0.5 no signal
887 Ankylosing Spondylitis 3 0.4 0.4 no signal
888 Mental Disorder 10 0.4 0.4 no signal
889 Oedema Peripheral 28 0.4 0.4 no signal
890 Renal Impairment 19 0.4 0.4 no signal
891 Hypoglycaemia 11 0.4 0.4 no signal
892 Disorientation 9 0.4 0.4 no signal
893 Bradycardia 12 0.4 0.4 no signal
894 Hypotension 45 0.4 0.4 no signal
895 Tooth Disorder 5 0.4 0.4 no signal
896 Pain Of Skin 6 0.4 0.4 no signal
897 Heart Rate Irregular 5 0.4 0.4 no signal
898 Drug Effect Decreased 12 0.4 0.4 no signal
899 Shock 5 0.4 0.4 no signal
900 Alopecia 43 0.4 0.4 no signal
901 Hip Fracture 7 0.4 0.4 no signal
902 Wrong Technique In Product Usage Process 44 0.4 0.4 no signal
903 Bone Disorder 4 0.4 0.4 no signal
904 Tinnitus 10 0.4 0.4 no signal
905 Adverse Event 20 0.4 0.4 no signal
906 Eye Swelling 8 0.4 0.4 no signal
907 Mental Status Changes 6 0.4 0.4 no signal
908 Atrial Fibrillation 21 0.4 0.4 no signal
909 Eye Irritation 12 0.4 0.4 no signal
910 Asthma 24 0.4 0.4 no signal
911 Withdrawal Syndrome 9 0.4 0.4 no signal
912 Hypocalcaemia 4 0.4 0.4 no signal
913 Visual Impairment 26 0.4 0.4 no signal
914 Incorrect Drug Administration Duration 6 0.4 0.4 no signal
915 Sleep Disorder 14 0.4 0.4 no signal
916 Blood Creatinine Increased 13 0.4 0.4 no signal
917 Flushing 20 0.4 0.4 no signal
918 Neoplasm Malignant 13 0.4 0.4 no signal
919 Emotional Disorder 6 0.4 0.4 no signal
920 Blood Cholesterol Increased 9 0.4 0.4 no signal
921 Rhabdomyolysis 8 0.4 0.4 no signal
922 No Adverse Event 34 0.4 0.4 no signal
923 Death 165 0.4 0.4 no signal
924 Cardio-respiratory Arrest 8 0.4 0.4 no signal
925 Head Injury 6 0.4 0.4 no signal
926 Metabolic Acidosis 6 0.4 0.4 no signal
927 Arrhythmia 9 0.4 0.4 no signal
928 Hypoaesthesia 28 0.4 0.4 no signal
929 Paraesthesia 29 0.4 0.4 no signal
930 Depression 42 0.4 0.4 no signal
931 Psoriasis 24 0.4 0.4 no signal
932 Dementia 5 0.3 0.3 no signal
933 Adverse Drug Reaction 16 0.3 0.3 no signal
934 Toxicity To Various Agents 30 0.3 0.3 no signal
935 Therapeutic Response Unexpected 8 0.3 0.3 no signal
936 Anger 6 0.3 0.3 no signal
937 Red Blood Cell Count Decreased 5 0.3 0.3 no signal
938 Gastrooesophageal Reflux Disease 14 0.3 0.3 no signal
939 Psoriatic Arthropathy 7 0.3 0.3 no signal
940 Chronic Obstructive Pulmonary Disease 9 0.3 0.3 no signal
941 Blindness 7 0.3 0.3 no signal
942 Diabetic Ketoacidosis 4 0.3 0.3 no signal
943 Blood Pressure Fluctuation 4 0.3 0.3 no signal
944 Blood Potassium Decreased 5 0.3 0.3 no signal
945 Product Administered At Inappropriate Site 3 0.3 0.3 no signal
946 Panic Attack 6 0.3 0.3 no signal
947 Coronary Artery Disease 5 0.3 0.3 no signal
948 Rectal Haemorrhage 7 0.3 0.3 no signal
949 Dermatitis Atopic 8 0.3 0.3 no signal
950 Therapy Interrupted 11 0.3 0.3 no signal
951 Dysphagia 15 0.3 0.3 no signal
952 Suicidal Ideation 14 0.3 0.3 no signal
953 Muscle Spasms 28 0.3 0.3 no signal
954 Depressed Mood 8 0.3 0.3 no signal
955 Menstruation Irregular 4 0.3 0.3 no signal
956 Menorrhagia 3 0.3 0.3 no signal
957 Urinary Retention 5 0.3 0.3 no signal
958 Balance Disorder 13 0.3 0.3 no signal
959 Agitation 11 0.3 0.3 no signal
960 Circumstance Or Information Capable Of Leading To Medication Error 5 0.3 0.3 no signal
961 Device Issue 13 0.3 0.3 no signal
962 Type 2 Diabetes Mellitus 5 0.3 0.3 no signal
963 Dyskinesia 6 0.3 0.3 no signal
964 Lung Neoplasm Malignant 6 0.3 0.3 no signal
965 Cardiac Arrest 12 0.3 0.3 no signal
966 Dyspepsia 14 0.3 0.3 no signal
967 Cerebrovascular Accident 24 0.3 0.3 no signal
968 Vision Blurred 19 0.3 0.3 no signal
969 Amnesia 9 0.3 0.3 no signal
970 Dysarthria 5 0.3 0.3 no signal
971 Tremor 22 0.3 0.3 no signal
972 Aphasia 4 0.3 0.3 no signal
973 Hypokalaemia 6 0.3 0.3 no signal
974 Somnolence 26 0.3 0.3 no signal
975 Convulsion 7 0.2 0.2 no signal
976 Pollakiuria 5 0.2 0.2 no signal
977 Device Malfunction 8 0.2 0.2 no signal
978 Hospitalisation 18 0.2 0.2 no signal
979 Therapy Cessation 6 0.2 0.2 no signal
980 Overdose 23 0.2 0.2 no signal
981 Coma 5 0.2 0.2 no signal
982 Pancreatic Carcinoma 3 0.2 0.2 no signal
983 Multiple Sclerosis Relapse 7 0.2 0.2 no signal
984 Drug Interaction 16 0.2 0.2 no signal
985 Extra Dose Administered 4 0.2 0.2 no signal
986 Dry Skin 13 0.2 0.2 no signal
987 Dry Mouth 8 0.2 0.2 no signal
988 Treatment Noncompliance 5 0.2 0.2 no signal
989 Chronic Kidney Disease 7 0.2 0.2 no signal
990 Memory Impairment 12 0.2 0.2 no signal
991 Cardiac Failure Congestive 7 0.2 0.2 no signal
992 Cognitive Disorder 4 0.2 0.2 no signal
993 Breast Cancer 8 0.2 0.2 no signal
994 Neuropathy Peripheral 8 0.2 0.2 no signal
995 Blood Glucose Increased 16 0.2 0.2 no signal
996 Blood Glucose Decreased 4 0.2 0.2 no signal
997 Exposure During Pregnancy 5 0.2 0.2 no signal
998 Hallucination 6 0.2 0.2 no signal
999 Dysgeusia 5 0.1 0.1 no signal
1000 Unevaluable Event 5 0.1 0.1 no signal
1001 Drug Dependence 10 0.1 0.1 no signal
1002 Product Quality Issue 8 0.1 0.1 no signal
1003 Drug Dose Omission By Device 4 0.1 0.1 no signal
1004 Drug Dose Omission 7 0.1 0.1 no signal
1005 Emotional Distress 5 0.1 0.1 no signal
1006 Confusional State 5 0.1 0.1 no signal