Reaction

C-Reactive Protein Abnormal reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 6,324 reports · 273 co-occurring drugs

As of the last recalculation, C-Reactive Protein Abnormal appears in 6,324 FAERS reports alongside 273 co-occurring drug terms. The strongest observed disproportionality signal is DICLOFENAC POTASSIUM, FILM COATED (PRR 556.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Diclofenac Potassium, Film Coated	1,162	556.6	646.2
Diclofenac Potassium Tablets	1,162	556.2	645.6
Desoximetasone	1,902	469.4	521.7
Cortisone Acetate	1,294	433.5	484.4
Diclofenac Potassium	1,162	433.4	485.8
Naproxen Sodium Tablet, Coated	1,282	390.6	431.6
Naproxen Sodium, Coated Tablets	1,282	390.6	431.6
Naproxen Sodium 220Mg	1,282	390.0	430.9
Pseudoephedrine Hydrochloride	1,009	384.4	426.4
Pseudoephedrine Hcl	1,009	358.4	394.7
Sulfasalazine	3,578	345.3	361.9
Leflunomide	3,855	309.0	320.9
Tocilizumab	3,774	268.5	277.7
Tofacitinib Citrate	888	259.2	278.1
Chlorhexidine Gluconate	642	257.3	276.8
Hydroxychloroquine	2,765	215.8	224.1
Abatacept	3,681	207.9	213.6
Hydroxychloroquine Sulfate	2,946	198.4	205.0
Diclofenac Sodium 1%	1,600	197.0	206.2
Diclofenac Sodium Topical	1,600	197.0	206.2
Diclofenac Sodium Topical Gel, 1%	1,600	196.6	205.8
Acetaminophen And Codeine	638	191.6	202.2
Adalimumab-Adaz	1,968	177.7	184.6
Adalimumab-Fkjp	1,784	176.2	183.2
Adalimumab-Aaty	1,782	172.1	178.9
Cetirizine Hydrochloride Allergy	1,229	165.5	172.5
Cetirizine Hydrochloride Tablets	1,229	165.5	172.5
Golimumab	2,449	152.8	157.2
Hydrocortisone Sodium Succinate	333	123.0	127.5
Methotrexate Sodium	4,659	117.0	118.2
Tofacitinib	3,219	115.9	118.0
Minocycline	378	113.4	117.2
Botulinum Toxin Type A	378	106.5	109.8
Sarilumab	751	106.1	109.1
Certolizumab Pegol	2,354	104.7	106.9
Methotrexate	4,291	102.3	103.3
Diclofenac	1,865	100.6	102.9
Infliximab	3,220	97.8	99.3
Doxyclycline Hyclate	468	97.6	100.4
Cetirizine	1,662	95.3	97.3
Triamcinolone Acetonide Ointment Usp, 0.05%	611	95.0	97.5
Cetiirizine	1,007	92.9	95.1
Alendronate Sodium	1,968	92.7	94.6
Rituximab	3,054	91.0	92.4
Calcium Gluconate	311	89.3	91.6
Isopropyl Alcohol	792	88.0	90.1
Anakinra	397	84.0	86.0
Aprepitant	431	82.4	84.3
Naproxen Sodium	2,280	81.6	82.9
Naproxen	1,485	81.0	82.6
Ustekinumab	1,765	78.3	79.7
Tramadol Hydrochloride	786	78.3	80.0
Risedronate Sodium	662	78.2	79.9
Alcohol	792	76.6	78.2
Etanercept	4,313	72.4	72.9
Triamcinolone Acetonide	611	71.9	73.4
Hydrocortisone Acetate	1,272	71.8	73.1
Thiamine Hydrochloride	249	68.5	69.9
Quetiapine Fumarate	560	68.4	69.7
Dimenhydrinate	211	67.4	68.7
Antacid	840	67.0	68.2
Fosaprepitant Dimeglumine	265	66.2	67.4
Calcium Carbonate	1,077	63.4	64.4
Celecoxib	1,816	63.3	64.2
Adalimumab	4,334	61.9	62.3
Secukinumab	2,058	61.7	62.5
Febuxostat Tablets 40 Mg	183	61.0	62.1
Febuxostat Tablets 80 Mg	183	61.0	62.1
Hydrocortisone	1,313	60.8	61.7
Folic Acid	2,657	59.8	60.4
Diclofenac Sodium	1,901	59.0	59.8
Anti-Itch	1,003	58.3	59.2
Anti-Pruritic	1,003	58.3	59.2
Antipruritic (Anti-Itch)	1,003	58.3	59.2
Cool Relief Gel With Aloe	1,003	58.3	59.2
Drs. Hydrocortisone	1,003	58.3	59.2
Hydrocortisone Continuous Spray	1,003	58.3	59.2
Hydrocortisone Spray	1,003	58.3	59.2
Anti-Itch Cream	1,003	58.3	59.2
Hydrocortisone Lotion	1,003	58.3	59.2
Hydrocortisone Cream 1%	1,003	58.3	59.2
Hydrocortisone Cream 1/2%	1,003	58.3	59.2
Hydrocortisone 1%	1,003	58.3	59.1
Hydrocortisone Cream	1,003	58.0	58.9
Pantoprazole Sodium In 0.9% Sodium Chloride	913	56.5	57.3
Pantoprazole Sodium Injection	913	56.5	57.3
Doxycycline Hyclate	930	53.0	53.7
Doxycycline	930	52.4	53.1
Canakinumab	165	51.5	52.3
Vitamin C	1,160	50.7	51.3
Candesartan	490	48.9	49.6
Febuxostat	239	48.7	49.4
Diltiazem Hydrochloride Extended-Release Tablets	161	47.8	48.4
Moxifloxacin Hydrochloride	280	47.5	48.2
Apremilast	1,577	46.9	47.4
Diphenhydramine Hydrochloride Capsule, Liquid Filled	289	46.6	47.2
Ascorbic Acid	311	46.2	46.9
Oxycodone And Acetaminophen Tablets	161	45.6	46.2
Cetirizine Hydrochloride	1,666	44.8	45.2
Methylprednisolone Sodium Succinate	569	44.2	44.8
Oxycodone	1,801	43.9	44.4
Atomoxetine Hydrochloride	298	43.2	43.7
Prednisone	3,242	42.5	42.8
Methylprednisolone Acetate	99	41.3	41.8
Azathioprine	911	39.6	40.0
Ramipril	1,199	39.1	39.5
Meloxicam	611	38.2	38.6
Trimethoprim	134	38.2	38.6
Erythromycin	204	37.0	37.4
Erenumab-Aooe	556	36.3	36.7
Moxifloxacin	145	34.6	35.0
Mycophenolate Mofetil Hydrochloride	1,161	34.2	34.5
Colchicine	262	34.1	34.4
Mycophenolate Mofetil	1,157	34.1	34.4
Acetaminophen Tablet Extended Release	1,839	33.0	33.3
Pain Reliever	1,839	33.0	33.3
Acetaminophen 500Mg	1,839	33.0	33.3
Mirabegron	366	33.0	33.3
Mepolizumab	445	31.6	31.9
Indomethacin	110	27.8	28.0
Magnesium	627	27.8	28.0
Ibuprofen Capsule	1,230	25.0	25.1
Ibuprofen Tablet, Film Coated	1,230	25.0	25.1
Ibupfrofen	1,230	25.0	25.1
Ibuprofen Tablets Usp, 200Mg	1,230	25.0	25.1
Ibuprofen Oral	1,230	24.9	25.1
Ibuprofen Capsules 200 Mg	1,230	24.9	25.1
Ibuprofen 200 Mg	1,230	24.9	25.1
Ibuprofen 200Mg	1,230	24.9	25.1
Pantoprazole Sodium	915	23.6	23.7
Oxycodone And Acetaminophen	161	23.3	23.5
Acetaminophen	2,113	22.8	22.9
Icosapent Ethyl	58	22.6	22.8
Alendronate Sodium Tablet	123	22.3	22.4
Pantoprazole	1,355	22.2	22.3
Ibuprofen And Diphenhydramine Citrate	153	22.1	22.3
Ibuprofen	1,349	20.5	20.6
Fish Oil	502	19.8	19.9
Lorazepam	923	19.6	19.7
Lansoprazole	900	19.2	19.3
Cyanocobalamin	187	19.2	19.3
Sulfamethoxazole And Trimethoprim	435	18.1	18.2
Dexlansoprazole	221	18.0	18.1
Tretinoin	44	18.0	18.1
Rosuvastatin Calcium	145	17.3	17.4
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	745	17.2	17.3
Methylprednisolone	645	17.0	17.1
Quetiapine	861	16.9	16.9
Ergocalciferol	1,524	16.9	16.9
Levothyroxine Sodium Anhydrous	471	16.6	16.7
Topiramate	438	16.5	16.6
Morphine	354	16.5	16.6
Diltiazem Hydrochloride	163	15.9	16.0
Pregabalin	1,081	15.6	15.6
Buprenorphine	397	15.0	15.1
Prednisolone	710	14.5	14.5
Prednisolone Oral	710	14.5	14.5
Prednisolone Oral Solution	710	14.5	14.5
Calcium	595	14.4	14.5
Cimetidine	37	12.7	12.8
Diphenhydramine Hydrochloride	583	12.6	12.7
Mesalamine	201	12.1	12.2
Oxycodone Hydrochloride	708	12.0	12.0
Ciclesonide	47	11.4	11.5
Cyclosporine	366	11.4	11.5
Metformin Hydrochloride Tablets	192	11.3	11.4
Metformin Hydrochloride Extended-Release Tablets	192	11.3	11.4
Metformin Hydrochloride Tablet	192	11.3	11.4
Metformin Hydrochloride	193	11.0	11.1
Vedolizumab	276	11.0	11.0
Lamotrigine	413	11.0	11.0
Zinc	81	10.9	11.0
Zinc Chloride	81	10.9	10.9
Human Immunoglobulin G	66	10.6	10.7
Brentuximab Vedotin	32	10.3	10.4
Zinc Gluconate	81	10.3	10.3
Ranitidine Hydrochloride	158	9.8	9.8
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	88	9.7	9.7
Lisinopril	780	9.4	9.4
Oxycodone Hydrochloride And Acetaminophen	247	8.5	8.5
Diphenhydramine	157	8.4	8.4
Cyclobenzaprine Hydrochloride	22	8.1	8.1
Ibuprofen Sodium	99	7.7	7.7
Ibuprofen Tablets, Coated	98	7.7	7.7
Levothyroxine Sodium	664	7.7	7.7
Albuterol	266	7.6	7.6
Candesartan Cilexetil	54	6.8	6.8
Fluticasone Furoate	24	6.5	6.6
Magnesium Hydroxide	23	5.6	5.6
Dexamethasone 1.5 Mg	469	5.6	5.6
Dexamethasone	469	5.5	5.5
Dexamethasone Sodium Phosphate	17	5.5	5.5
Infliximab-Dyyb	47	5.3	5.3
Pramipexole	24	5.2	5.2
Baricitinib	15	5.1	5.1
Cyclobenzaprine	77	5.1	5.1
Bendamustine Hydrochloride	17	4.7	4.7
Trazodone Hydrochloride	22	4.6	4.6
Budesonide	79	4.5	4.5
Tobramycin Solution	16	4.4	4.4
Tobramycin Sulfate	16	4.3	4.3
Telmisartan	23	4.3	4.3
Albuterol Sulfate	362	4.2	4.2
Gentamicin Sulfate	20	4.2	4.2
Bendamustine Hcl	19	4.0	4.0
Canagliflozin	36	4.0	4.0
Leucovorin Calcium	23	4.0	4.0
Metronidazole Topical	57	4.0	4.0
Mycophenilic Acid	24	3.8	3.8
Nifedipine	54	3.8	3.8
Valsartan Oral	62	3.8	3.8
Naproxen Sodium Tablet	60	3.7	3.8
Ranitidine	219	3.7	3.7
Ciprofolxacin	80	3.7	3.7
Ciprofloxacin Tablets	80	3.7	3.7
Hydromorphone Hydrochloride	101	3.7	3.7
Amitriptyline Hydrochloride	19	3.6	3.6
Loperamide Hydrochloride Oral	11	3.5	3.6
Magnesium Oxide	44	3.5	3.5
Esomeprazole Magnesium Capsule, Delayed Release	15	3.4	3.4
Esomeprazole Magnesium Delayed Release Capsules	15	3.4	3.4
Esomeprazole Magnesium Dihydrate	15	3.4	3.4
Ciprofloxacin Hydrochloride	99	3.4	3.4
Oseltamivir	8	3.3	3.3
Olmesartan Medoxomil	36	3.3	3.3
Mycophenolic Acid	32	3.3	3.3
Sodium Bicarbonate	23	3.3	3.3
Sodium Bicarbonate Injection,	23	3.3	3.3
Irbesartan	44	3.3	3.3
Metformin	337	3.2	3.2
Atenolol	128	3.2	3.2
Upadacitinib	76	3.1	3.1
Ciprofloxacin	85	3.1	3.1
Metronidazole	59	3.1	3.1
Gentamicin	12	3.0	3.0
Loperamide Hcl	11	2.8	2.8
Atorvastatin Calcium	206	2.8	2.8
Iron Sucrose	8	2.8	2.8
Estradiol	69	2.6	2.6
Lamotirigine	57	2.6	2.6
Lamotrigine Extended-Release	57	2.6	2.6
Lamotrigine Chewable Dispersible	57	2.6	2.6
Morphine Sulfate	96	2.6	2.6
Iron	52	2.6	2.6
Bleomycin Sulfate	8	2.6	2.6
Cefazolin	7	2.5	2.5
Ketoprofen	10	2.5	2.5
Fluticasone Propionate Nasal	23	2.5	2.5
Valsartan	74	2.3	2.3
Latanoprost	35	2.3	2.3
Tobramycin	16	2.2	2.2
Cefazolin Sodium	8	2.2	2.2
Bupivacaine	6	2.1	2.1
Bupropion Hydrochloride	62	2.1	2.1
Bupropion	28	2.1	2.1
Propranolol Hydrochloride	45	2.1	2.1
Metformin Er 500 Mg	182	2.0	2.0
Metformin Er 750 Mg	182	2.0	2.0
Apixaban	40	2.0	2.0
Prednisolone Acetate	6	1.9	1.9
Daptomycin	5	1.8	1.8
Dapagliflozin	17	1.8	1.8
Dorzolamide Hydrochloride And Timolol Maleate	4	1.7	1.7
Pembrolizumab	51	1.6	1.6
Ixekizumab	16	1.4	1.4
Rivaroxaban	89	1.4	1.4
Pemetrexed	9	1.4	1.4
Ifosfamide	9	1.4	1.4
Bortezomib	33	1.2	1.2
Azacitidine For	6	1.1	1.1
Blinatumomab	3	0.9	0.9
Salicylic Acid	14	0.9	0.9
Onabotulinumtoxina	20	0.9	0.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.