OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Cholestyramine

1,145 flagged reaction(s) · 53,523 total co-reports · max PRR 438.5
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Intestinal Intraepithelial Lymphocytes Increased 13 438.5 439.0 signal
2 Microvillous Inclusion Disease 13 360.7 361.1 signal
3 Pulmonary Interstitial Emphysema Syndrome 19 267.9 268.4 signal
4 Alveolar Lung Disease 20 203.6 203.9 signal
5 Probiotic Therapy 10 197.7 197.9 signal
6 Gastrointestinal Anastomotic Stenosis 9 180.0 180.2 signal
7 Cryptitis 13 178.9 179.1 signal
8 Foreign Body In Mouth 9 172.0 172.2 signal
9 Bile Acid Malabsorption 23 160.2 160.5 signal
10 Bile Acids Increased 9 103.2 103.3 signal
11 Nerve Degeneration 9 91.6 91.7 signal
12 Apoptosis 14 81.9 82.0 signal
13 Product Solubility Abnormal 179 64.8 65.8 signal
14 Laparotomy 13 51.1 51.1 signal
15 Post Procedural Diarrhoea 14 49.4 49.4 signal
16 Short-bowel Syndrome 17 46.7 46.8 signal
17 Anastomotic Ulcer 11 42.9 43.0 signal
18 Product Physical Consistency Issue 131 42.8 43.3 signal
19 Intestinal Anastomosis 15 42.7 42.7 signal
20 Gastrointestinal Stoma Output Increased 11 42.4 42.5 signal
21 Terminal Ileitis 14 41.5 41.5 signal
22 Faecal Volume Decreased 10 36.8 36.9 signal
23 Thyrotoxic Crisis 22 34.6 34.7 signal
24 Faecal Calprotectin Increased 55 31.3 31.4 signal
25 Gastrointestinal Wall Thickening 26 31.1 31.1 signal
26 Diffuse Alveolar Damage 20 30.7 30.8 signal
27 Erosive Duodenitis 13 28.9 28.9 signal
28 Stoma Complication 15 26.0 26.0 signal
29 Therapeutic Reaction Time Decreased 41 24.6 24.7 signal
30 Ileal Stenosis 22 21.8 21.9 signal
31 Small Intestinal Stenosis 13 21.6 21.6 signal
32 Foetal Heart Rate Abnormal 11 21.0 21.0 signal
33 Foreign Body In Throat 36 20.9 21.0 signal
34 Product Taste Abnormal 157 20.6 20.9 signal
35 Enterocutaneous Fistula 10 20.1 20.1 signal
36 Vascular Device Infection 51 19.9 20.0 signal
37 Cholangitis Sclerosing 23 19.7 19.7 signal
38 Mesenteric Vein Thrombosis 11 19.4 19.4 signal
39 Cerebral Venous Sinus Thrombosis 9 19.4 19.4 signal
40 Intestinal Stenosis 46 19.3 19.3 signal
41 Biopsy 10 19.0 19.0 signal
42 Alpha Haemolytic Streptococcal Infection 10 18.9 19.0 signal
43 Anal Fissure 56 18.5 18.6 signal
44 Colitis Microscopic 49 18.4 18.5 signal
45 Chronic Kidney Disease-mineral And Bone Disorder 11 18.0 18.0 signal
46 Gastric Polyps 22 17.1 17.1 signal
47 Streptococcal Bacteraemia 10 16.4 16.4 signal
48 Hyperparathyroidism Secondary 23 16.0 16.0 signal
49 Gastrointestinal Stoma Complication 14 15.8 15.8 signal
50 Sacroiliitis 17 15.8 15.8 signal
51 Duodenitis 27 15.5 15.5 signal
52 Product Residue Present 45 14.9 15.0 signal
53 Abdominal Adhesions 26 14.4 14.4 signal
54 Drug Level Above Therapeutic 36 13.9 14.0 signal
55 Proctalgia 50 13.7 13.7 signal
56 Abdominal Rigidity 21 13.7 13.7 signal
57 Foreign Body In Respiratory Tract 10 13.3 13.3 signal
58 Blood Electrolytes Abnormal 9 12.8 12.8 signal
59 Nephrogenic Anaemia 33 12.4 12.4 signal
60 Sprue-like Enteropathy 33 11.7 11.7 signal
61 Ischaemic Hepatitis 9 11.7 11.7 signal
62 Abdominal Hernia 30 11.5 11.6 signal
63 Intestinal Resection 35 11.5 11.5 signal
64 Infusion Site Discharge 11 11.3 11.3 signal
65 Eosinophilic Pneumonia 20 11.2 11.2 signal
66 Large Intestine Polyp 44 11.1 11.2 signal
67 Product Use Complaint 96 10.9 10.9 signal
68 Costochondritis 10 10.7 10.8 signal
69 Cholestatic Liver Injury 13 10.6 10.7 signal
70 Weight Gain Poor 14 10.6 10.6 signal
71 Small Intestinal Obstruction 74 10.6 10.6 signal
72 Frequent Bowel Movements 158 10.3 10.4 signal
73 Enteritis 36 9.9 10.0 signal
74 Faeces Soft 41 9.9 10.0 signal
75 Product Packaging Difficult To Open 14 9.9 9.9 signal
76 Drug Level Below Therapeutic 31 9.9 9.9 signal
77 Poor Venous Access 58 9.9 9.9 signal
78 Drug Level Decreased 57 9.8 9.8 signal
79 Large Intestinal Stenosis 11 9.7 9.8 signal
80 Ileostomy 14 9.7 9.7 signal
81 Lymphocyte Count Increased 18 9.7 9.7 signal
82 Fistula 62 9.6 9.7 signal
83 Oropharyngeal Discomfort 49 9.6 9.6 signal
84 Blood Magnesium Decreased 47 9.5 9.6 signal
85 Intestinal Polyp 9 9.5 9.5 signal
86 Erythema Nodosum 19 9.5 9.5 signal
87 Renal Mass 11 9.3 9.4 signal
88 Hypovolaemia 31 9.3 9.3 signal
89 Hepatic Fibrosis 18 9.2 9.2 signal
90 Rebound Acid Hypersecretion 16 9.1 9.2 signal
91 Hypervolaemia 25 9.1 9.1 signal
92 Malabsorption 27 9.1 9.1 signal
93 Plasma Cell Myeloma Recurrent 17 9.1 9.1 signal
94 Bile Duct Obstruction 10 9.1 9.1 signal
95 Escherichia Bacteraemia 12 9.1 9.1 signal
96 Clostridium Test Positive 11 8.8 8.8 signal
97 Crohn's Disease 35 8.8 8.8 signal
98 Anorectal Disorder 10 8.7 8.7 signal
99 Varices Oesophageal 15 8.7 8.7 signal
100 Choking Sensation 27 8.6 8.6 signal
101 Anal Incontinence 43 8.5 8.5 signal
102 Clostridium Difficile Colitis 51 8.4 8.4 signal
103 Abnormal Faeces 39 8.3 8.4 signal
104 Clostridium Difficile Infection 102 8.2 8.3 signal
105 Escherichia Urinary Tract Infection 20 8.2 8.3 signal
106 Product Odour Abnormal 48 8.1 8.1 signal
107 Gastrointestinal Obstruction 11 8.1 8.1 signal
108 Serum Ferritin Increased 24 8.0 8.0 signal
109 Anal Fistula 24 7.9 7.9 signal
110 Diverticulum 32 7.8 7.8 signal
111 Infrequent Bowel Movements 11 7.7 7.7 signal
112 Intestinal Obstruction 164 7.7 7.8 signal
113 Bowel Movement Irregularity 33 7.6 7.6 signal
114 Functional Gastrointestinal Disorder 15 7.6 7.6 signal
115 Abdominal Tenderness 21 7.4 7.4 signal
116 Hyperammonaemia 21 7.4 7.4 signal
117 Hepatic Encephalopathy 39 7.3 7.3 signal
118 Aphthous Ulcer 32 7.3 7.3 signal
119 Defaecation Urgency 29 7.3 7.3 signal
120 Abdominal Mass 11 7.2 7.2 signal
121 Anorectal Discomfort 22 7.2 7.2 signal
122 Iron Deficiency 18 7.1 7.1 signal
123 Intraventricular Haemorrhage 10 7.0 7.0 signal
124 Gastrointestinal Inflammation 31 7.0 7.0 signal
125 Cholecystitis Infective 11 6.9 7.0 signal
126 Anal Abscess 21 6.8 6.9 signal
127 Reaction To Excipient 9 6.8 6.8 signal
128 Diverticulum Intestinal 17 6.8 6.8 signal
129 Lactose Intolerance 10 6.8 6.8 signal
130 Colitis 143 6.6 6.7 signal
131 Colectomy 21 6.6 6.6 signal
132 Vitamin B12 Deficiency 15 6.5 6.5 signal
133 Hepatic Steatosis 69 6.5 6.5 signal
134 Large Intestinal Ulcer 10 6.5 6.5 signal
135 Ear Congestion 10 6.5 6.5 signal
136 Infusion Site Extravasation 23 6.5 6.5 signal
137 Hyperthyroidism 53 6.4 6.4 signal
138 Gastrointestinal Sounds Abnormal 18 6.4 6.4 signal
139 Blood Pressure Diastolic Decreased 27 6.4 6.4 signal
140 Retching 77 6.3 6.4 signal
141 Haemorrhoids 70 6.3 6.3 signal
142 Prostatomegaly 14 6.2 6.2 signal
143 Labyrinthitis 9 6.2 6.2 signal
144 Renal Cyst 28 6.2 6.2 signal
145 Malnutrition 39 6.1 6.2 signal
146 Pancreatic Carcinoma Metastatic 10 6.1 6.1 signal
147 Body Temperature Decreased 34 6.0 6.0 signal
148 Musculoskeletal Chest Pain 53 6.0 6.0 signal
149 Infusion Site Haemorrhage 11 5.9 5.9 signal
150 Metabolic Encephalopathy 10 5.8 5.8 signal
151 Irritable Bowel Syndrome 71 5.8 5.8 signal
152 Hiatus Hernia 43 5.8 5.8 signal
153 Pancreatic Disorder 16 5.7 5.7 signal
154 Haemorrhoidal Haemorrhage 16 5.7 5.7 signal
155 Ileus 40 5.7 5.7 signal
156 Product Substitution Issue 183 5.6 5.6 signal
157 Bile Duct Stone 10 5.5 5.5 signal
158 Biliary Colic 9 5.5 5.5 signal
159 Seasonal Allergy 44 5.5 5.5 signal
160 Weight Fluctuation 32 5.4 5.4 signal
161 Impaired Gastric Emptying 39 5.3 5.4 signal
162 Spondylitis 11 5.3 5.3 signal
163 Hypomagnesaemia 42 5.3 5.3 signal
164 Blood Pressure Diastolic Increased 14 5.3 5.3 signal
165 Hepatic Lesion 13 5.3 5.3 signal
166 Cholecystectomy 34 5.2 5.2 signal
167 Diarrhoea Haemorrhagic 28 5.2 5.2 signal
168 Drug Ineffective For Unapproved Indication 165 5.2 5.2 signal
169 Abdominal Abscess 13 5.1 5.2 signal
170 Clostridial Infection 10 5.1 5.1 signal
171 Infusion Site Swelling 18 5.1 5.1 signal
172 Portal Hypertension 9 5.1 5.1 signal
173 Social Problem 12 5.1 5.1 signal
174 Systemic Inflammatory Response Syndrome 11 5.1 5.1 signal
175 Infusion Site Pruritus 9 5.0 5.0 signal
176 Immune-mediated Enterocolitis 10 5.0 5.0 signal
177 Cholelithiasis 93 5.0 5.0 signal
178 Hepatitis Cholestatic 17 5.0 5.0 signal
179 Flatulence 160 4.9 5.0 signal
180 Squamous Cell Carcinoma Of Skin 17 4.9 4.9 signal
181 Cholecystitis Chronic 19 4.9 4.9 signal
182 Vitamin D Deficiency 27 4.8 4.9 signal
183 End Stage Renal Disease 51 4.8 4.9 signal
184 Low Birth Weight Baby 22 4.8 4.8 signal
185 Obstruction 11 4.8 4.8 signal
186 Intestinal Ischaemia 15 4.8 4.8 signal
187 Hepatic Cirrhosis 51 4.8 4.8 signal
188 Spinal Osteoarthritis 24 4.8 4.8 signal
189 Viral Upper Respiratory Tract Infection 13 4.7 4.8 signal
190 Basal Cell Carcinoma 42 4.7 4.7 signal
191 Intervertebral Disc Degeneration 25 4.7 4.7 signal
192 Vitamin D Decreased 23 4.7 4.7 signal
193 Plantar Fasciitis 9 4.7 4.7 signal
194 Hyperlipidaemia 32 4.7 4.7 signal
195 Blood Albumin Decreased 21 4.6 4.6 signal
196 Hepatic Cyst 9 4.6 4.6 signal
197 Diarrhoea 1,695 4.6 5.2 signal
198 Gallbladder Disorder 47 4.6 4.6 signal
199 Drug Specific Antibody Present 17 4.6 4.6 signal
200 Blood Alkaline Phosphatase Increased 65 4.6 4.6 signal
201 Appetite Disorder 17 4.6 4.6 signal
202 Hepatic Enzyme Abnormal 13 4.6 4.6 signal
203 Polyp 17 4.5 4.5 signal
204 Blood Potassium Decreased 78 4.5 4.6 signal
205 Post Procedural Infection 21 4.5 4.5 signal
206 Nephrolithiasis 118 4.5 4.5 signal
207 Diverticulitis 71 4.5 4.5 signal
208 Umbilical Hernia 12 4.5 4.5 signal
209 Gastrointestinal Pain 28 4.5 4.5 signal
210 Haematocrit Decreased 51 4.5 4.5 signal
211 Gastroenteritis 37 4.4 4.4 signal
212 Electrolyte Imbalance 29 4.4 4.4 signal
213 Hernia 48 4.4 4.4 signal
214 Incontinence 26 4.3 4.3 signal
215 International Normalised Ratio Decreased 10 4.3 4.3 signal
216 Hypokalaemia 111 4.2 4.3 signal
217 Red Cell Distribution Width Increased 10 4.2 4.2 signal
218 Tongue Discomfort 10 4.2 4.2 signal
219 Choking 46 4.1 4.2 signal
220 Blood Pressure Fluctuation 57 4.1 4.2 signal
221 Abdominal Pain 546 4.1 4.3 signal
222 Abdominal Distension 239 4.0 4.1 signal
223 Cholecystitis Acute 13 4.0 4.0 signal
224 Multiple Allergies 18 4.0 4.0 signal
225 Iron Deficiency Anaemia 21 4.0 4.0 signal
226 Intentional Product Use Issue 201 4.0 4.0 signal
227 Oesophageal Candidiasis 9 4.0 4.0 signal
228 Tooth Infection 30 4.0 4.0 signal
229 Generalised Oedema 28 4.0 4.0 signal
230 Gastrointestinal Motility Disorder 12 4.0 4.0 signal
231 Throat Irritation 101 3.9 4.0 signal
232 Appendicitis 21 3.9 4.0 signal
233 Faecal Incontinence 11 3.9 3.9 signal
234 Azotaemia 9 3.9 3.9 signal
235 Flank Pain 21 3.9 3.9 signal
236 Chronic Kidney Disease 171 3.9 3.9 signal
237 Glomerular Filtration Rate Decreased 27 3.9 3.9 signal
238 Osteopenia 34 3.9 3.9 signal
239 Dehydration 297 3.9 4.0 signal
240 Jaundice 60 3.9 3.9 signal
241 Uveitis 30 3.9 3.9 signal
242 Haemoglobin Increased 10 3.9 3.9 signal
243 Faecaloma 12 3.9 3.9 signal
244 Odynophagia 13 3.8 3.8 signal
245 Aneurysm 11 3.8 3.8 signal
246 Infusion Site Pain 28 3.8 3.8 signal
247 Rectal Haemorrhage 94 3.8 3.8 signal
248 Pleurisy 13 3.8 3.8 signal
249 Autoimmune Hepatitis 15 3.8 3.8 signal
250 Insurance Issue 32 3.8 3.8 signal
251 Heart Rate Decreased 76 3.8 3.8 signal
252 Blood Pressure Systolic Increased 42 3.7 3.8 signal
253 Abscess 34 3.7 3.7 signal
254 Blood Iron Decreased 25 3.7 3.7 signal
255 Hepatic Pain 9 3.7 3.7 signal
256 Polyarthritis 11 3.7 3.7 signal
257 Hypoalbuminaemia 16 3.7 3.7 signal
258 Metastasis 15 3.7 3.7 signal
259 Oropharyngeal Pain 193 3.6 3.7 signal
260 Muscle Strain 18 3.6 3.6 signal
261 Ocular Icterus 9 3.6 3.6 signal
262 Postoperative Wound Infection 14 3.6 3.6 signal
263 Pre-existing Condition Improved 13 3.6 3.6 signal
264 Infusion Site Erythema 17 3.6 3.6 signal
265 Coagulopathy 34 3.6 3.6 signal
266 Gastroenteritis Viral 37 3.6 3.6 signal
267 Arthropod Bite 15 3.6 3.6 signal
268 Mucous Stools 10 3.5 3.5 signal
269 Cystitis 64 3.5 3.5 signal
270 Haematochezia 110 3.5 3.5 signal
271 Blood Bilirubin Increased 54 3.5 3.5 signal
272 Lipase Increased 15 3.4 3.4 signal
273 Atelectasis 19 3.4 3.4 signal
274 Skin Cancer 42 3.4 3.4 signal
275 Cholecystitis 23 3.4 3.4 signal
276 Gastrointestinal Infection 17 3.3 3.3 signal
277 Abdominal Pain Lower 48 3.3 3.3 signal
278 Constipation 409 3.3 3.4 signal
279 Eosinophilia 33 3.3 3.3 signal
280 Cholestasis 36 3.3 3.3 signal
281 Weight Decreased 517 3.2 3.3 signal
282 Increased Tendency To Bruise 17 3.2 3.2 signal
283 Ascites 54 3.2 3.2 signal
284 Coeliac Disease 18 3.2 3.2 signal
285 Inflammatory Bowel Disease 18 3.2 3.2 signal
286 Upper Respiratory Tract Infection 84 3.2 3.2 signal
287 Tenderness 19 3.2 3.2 signal
288 Nocturia 22 3.2 3.2 signal
289 Inflammation 93 3.2 3.2 signal
290 Skin Mass 12 3.2 3.2 signal
291 Product Distribution Issue 16 3.2 3.2 signal
292 Red Blood Cell Sedimentation Rate Increased 20 3.1 3.2 signal
293 Blood Potassium Increased 29 3.1 3.1 signal
294 Intestinal Perforation 20 3.1 3.1 signal
295 Abnormal Loss Of Weight 12 3.1 3.1 signal
296 Blood Calcium Decreased 20 3.1 3.1 signal
297 Ammonia Increased 9 3.1 3.1 signal
298 Mouth Ulceration 37 3.1 3.1 signal
299 Gastrooesophageal Reflux Disease 141 3.1 3.1 signal
300 Gamma-glutamyltransferase Increased 39 3.1 3.1 signal
301 Faeces Discoloured 38 3.1 3.1 signal
302 Lower Gastrointestinal Haemorrhage 13 3.1 3.1 signal
303 Device Related Infection 27 3.1 3.1 signal
304 Muscle Atrophy 22 3.1 3.1 signal
305 Herpes Virus Infection 10 3.0 3.0 signal
306 Compression Fracture 9 3.0 3.0 signal
307 Large Intestine Perforation 12 3.0 3.0 signal
308 Gout 31 3.0 3.0 signal
309 Urinary Tract Infection 293 3.0 3.1 signal
310 Rales 10 3.0 3.0 signal
311 Post Procedural Complication 33 3.0 3.0 signal
312 Joint Stiffness 45 3.0 3.0 signal
313 Productive Cough 81 3.0 3.0 signal
314 Night Sweats 55 3.0 3.0 signal
315 Rotator Cuff Syndrome 22 3.0 3.0 signal
316 Acute Kidney Injury 259 3.0 3.0 signal
317 Economic Problem 26 2.9 3.0 signal
318 Covid-19 Pneumonia 20 2.9 2.9 signal
319 Concussion 13 2.9 2.9 signal
320 Gastrointestinal Disorder 148 2.9 2.9 signal
321 Pelvic Fracture 13 2.9 2.9 signal
322 Gingivitis 9 2.9 2.9 signal
323 Hyperbilirubinaemia 17 2.9 2.9 signal
324 Brain Fog 24 2.9 2.9 signal
325 Red Blood Cell Count Decreased 47 2.9 2.9 signal
326 Full Blood Count Decreased 33 2.9 2.9 signal
327 Ulcer 26 2.8 2.9 signal
328 Splenomegaly 19 2.8 2.8 signal
329 Ear Infection 43 2.8 2.8 signal
330 Acute Respiratory Failure 31 2.8 2.8 signal
331 Myopathy 14 2.8 2.8 signal
332 Rhinorrhoea 104 2.8 2.8 signal
333 Renal Failure 215 2.8 2.8 signal
334 Eye Infection 18 2.8 2.8 signal
335 Osteomyelitis 29 2.8 2.8 signal
336 Ecchymosis 11 2.8 2.8 signal
337 Blood Pressure Increased 245 2.8 2.8 signal
338 Impaired Quality Of Life 23 2.8 2.8 signal
339 Urine Output Decreased 14 2.8 2.8 signal
340 Hiccups 13 2.8 2.8 signal
341 Intestinal Haemorrhage 9 2.8 2.8 signal
342 Groin Pain 14 2.8 2.8 signal
343 Sputum Discoloured 15 2.8 2.8 signal
344 Heart Rate Irregular 36 2.8 2.8 signal
345 Oral Discomfort 22 2.8 2.8 signal
346 Enterocolitis 9 2.8 2.8 signal
347 Scar 27 2.7 2.8 signal
348 Bronchitis 117 2.7 2.8 signal
349 Therapeutic Response Shortened 50 2.7 2.8 signal
350 Blood Uric Acid Increased 9 2.7 2.7 signal
351 Gastritis 41 2.7 2.7 signal
352 Sinus Congestion 21 2.7 2.7 signal
353 Pancreatitis 82 2.7 2.7 signal
354 Dyspepsia 152 2.7 2.7 signal
355 Tendonitis 24 2.7 2.7 signal
356 Liver Function Test Abnormal 45 2.7 2.7 signal
357 Alanine Aminotransferase Increased 94 2.7 2.7 signal
358 Arthralgia 633 2.7 2.8 signal
359 Aspartate Aminotransferase Increased 81 2.7 2.7 signal
360 Sciatica 24 2.6 2.6 signal
361 Bladder Disorder 15 2.6 2.6 signal
362 Mitral Valve Incompetence 17 2.6 2.6 signal
363 Micturition Urgency 17 2.6 2.6 signal
364 Uterine Leiomyoma 11 2.6 2.6 signal
365 Hypophosphataemia 11 2.6 2.6 signal
366 Ovarian Cyst 15 2.6 2.6 signal
367 Colitis Ischaemic 10 2.6 2.6 signal
368 Oxygen Saturation Decreased 83 2.6 2.6 signal
369 Haemoglobin Decreased 153 2.6 2.6 signal
370 Breast Mass 10 2.6 2.6 signal
371 Squamous Cell Carcinoma 14 2.6 2.6 signal
372 Plasma Cell Myeloma 58 2.6 2.6 signal
373 Neck Pain 83 2.6 2.6 signal
374 Sleep Apnoea Syndrome 28 2.6 2.6 signal
375 Supraventricular Tachycardia 14 2.6 2.6 signal
376 Neuropathy Peripheral 138 2.5 2.6 signal
377 Middle Insomnia 27 2.5 2.5 signal
378 Stress 104 2.5 2.5 signal
379 Thrombotic Microangiopathy 14 2.5 2.5 signal
380 Joint Effusion 10 2.5 2.5 signal
381 Hypothyroidism 46 2.5 2.5 signal
382 Fungal Infection 48 2.5 2.5 signal
383 Lymphadenopathy 51 2.5 2.5 signal
384 Skin Lesion 39 2.5 2.5 signal
385 Extrasystoles 10 2.5 2.5 signal
386 Laboratory Test Abnormal 42 2.5 2.5 signal
387 Exostosis 13 2.5 2.5 signal
388 Skin Plaque 12 2.5 2.5 signal
389 Eructation 27 2.5 2.5 signal
390 Renal Failure Acute 61 2.5 2.5 signal
391 Product Supply Issue 10 2.5 2.5 signal
392 Nerve Compression 13 2.5 2.5 signal
393 Osteoporosis 58 2.5 2.5 signal
394 Blood Thyroid Stimulating Hormone Increased 13 2.5 2.5 signal
395 Decreased Activity 15 2.4 2.4 signal
396 Rash Maculo-papular 31 2.4 2.4 signal
397 Decreased Appetite 324 2.4 2.5 signal
398 Neutropenic Sepsis 10 2.4 2.4 signal
399 Arthritis 110 2.4 2.5 signal
400 Therapy Partial Responder 21 2.4 2.4 signal
401 Contusion 134 2.4 2.4 signal
402 Pyelonephritis 12 2.4 2.4 signal
403 Oedema Peripheral 170 2.4 2.4 signal
404 Limb Discomfort 43 2.4 2.4 signal
405 Osteoarthritis 59 2.4 2.4 signal
406 Back Injury 15 2.4 2.4 signal
407 Rash Papular 31 2.4 2.4 signal
408 Cardiac Murmur 12 2.4 2.4 signal
409 Arteriosclerosis 13 2.4 2.4 signal
410 Dry Throat 14 2.4 2.4 signal
411 Hypocalcaemia 26 2.4 2.4 signal
412 Oesophagitis 15 2.4 2.4 signal
413 Wheezing 81 2.4 2.4 signal
414 Limb Injury 37 2.4 2.4 signal
415 Sinusitis 140 2.4 2.4 signal
416 Neutrophil Count Increased 14 2.4 2.4 signal
417 Bacteraemia 16 2.4 2.4 signal
418 Cough 380 2.4 2.4 signal
419 Skin Ulcer 35 2.4 2.4 signal
420 Foot Deformity 15 2.4 2.4 signal
421 Decubitus Ulcer 11 2.4 2.4 signal
422 Rash Macular 47 2.4 2.4 signal
423 Respiratory Rate Increased 12 2.4 2.4 signal
424 Respiratory Tract Infection 35 2.4 2.4 signal
425 Nerve Injury 15 2.3 2.3 signal
426 Upper-airway Cough Syndrome 11 2.3 2.3 signal
427 Polyuria 11 2.3 2.3 signal
428 Back Pain 312 2.3 2.4 signal
429 Pulmonary Hypertension 28 2.3 2.3 signal
430 Product Availability Issue 30 2.3 2.3 signal
431 Wrist Fracture 16 2.3 2.3 signal
432 Nasal Congestion 78 2.3 2.3 signal
433 Hyperaesthesia 11 2.3 2.3 signal
434 Multiple Organ Dysfunction Syndrome 37 2.3 2.3 signal
435 General Symptom 10 2.3 2.3 signal
436 Troponin Increased 10 2.3 2.3 signal
437 Hepatic Enzyme Increased 90 2.3 2.3 signal
438 Muscle Spasms 243 2.3 2.3 signal
439 Herpes Zoster 76 2.3 2.3 signal
440 Hepatomegaly 13 2.3 2.3 signal
441 Nephrotic Syndrome 9 2.3 2.3 signal
442 Oedema 71 2.3 2.3 signal
443 Sepsis 146 2.3 2.3 signal
444 Oral Candidiasis 17 2.3 2.3 signal
445 Colitis Ulcerative 58 2.3 2.3 signal
446 Pancreatitis Acute 29 2.3 2.3 signal
447 Tooth Disorder 29 2.3 2.3 signal
448 Blood Triglycerides Increased 23 2.3 2.3 signal
449 Papule 9 2.3 2.3 signal
450 Pharyngitis Streptococcal 14 2.3 2.3 signal
451 Peripheral Swelling 198 2.3 2.3 signal
452 Hyperkalaemia 45 2.3 2.3 signal
453 Thrombosis 104 2.3 2.3 signal
454 Cellulitis 65 2.2 2.3 signal
455 Wound Infection 14 2.2 2.2 signal
456 Toxic Skin Eruption 13 2.2 2.2 signal
457 Tinnitus 59 2.2 2.2 signal
458 Carpal Tunnel Syndrome 18 2.2 2.2 signal
459 Off Label Use 1,111 2.2 2.4 signal
460 Dyspnoea Exertional 48 2.2 2.2 signal
461 Musculoskeletal Discomfort 22 2.2 2.2 signal
462 Pulmonary Mass 19 2.2 2.2 signal
463 Hip Fracture 41 2.2 2.2 signal
464 Duodenal Ulcer 9 2.2 2.2 signal
465 Tooth Abscess 13 2.2 2.2 signal
466 Eye Haemorrhage 17 2.2 2.2 signal
467 Abdominal Pain Upper 261 2.2 2.2 signal
468 Tooth Fracture 14 2.2 2.2 signal
469 Hand Fracture 9 2.2 2.2 signal
470 Electrocardiogram Abnormal 10 2.2 2.2 signal
471 Dental Caries 14 2.2 2.2 signal
472 Drug-induced Liver Injury 39 2.2 2.2 signal
473 Candida Infection 21 2.2 2.2 signal
474 Laceration 12 2.2 2.2 signal
475 Gingival Pain 10 2.2 2.2 signal
476 Atrial Fibrillation 122 2.2 2.2 signal
477 Cataract 74 2.2 2.2 signal
478 Illness 125 2.2 2.2 signal
479 Bursitis 15 2.2 2.2 signal
480 Asthenia 467 2.2 2.2 signal
481 Inappropriate Schedule Of Product Administration 219 2.2 2.2 signal
482 Abdominal Discomfort 207 2.2 2.2 signal
483 Transfusion 13 2.2 2.2 signal
484 Head Injury 39 2.2 2.2 signal
485 Ear Pain 24 2.2 2.2 signal
486 Influenza 138 2.2 2.2 signal
487 Vitreous Floaters 12 2.2 2.2 signal
488 Shock Haemorrhagic 10 2.1 2.1 signal
489 Myositis 11 2.1 2.1 signal
490 Encephalopathy 30 2.1 2.1 signal
491 Platelet Count Increased 16 2.1 2.1 signal
492 Rash Pruritic 66 2.1 2.1 signal
493 Mental Status Changes 34 2.1 2.1 signal
494 Blood Pressure Decreased 81 2.1 2.1 signal
495 Liver Function Test Increased 26 2.1 2.1 signal
496 Ligament Sprain 12 2.1 2.1 signal
497 Nasopharyngitis 224 2.1 2.1 signal
498 Restless Legs Syndrome 22 2.1 2.1 signal
499 Chronic Obstructive Pulmonary Disease 63 2.1 2.1 signal
500 White Blood Cell Count Decreased 131 2.1 2.1 signal
501 Hydronephrosis 9 2.1 2.1 signal
502 Pneumonia Bacterial 11 2.1 2.1 signal
503 Pneumonia 389 2.1 2.1 signal
504 Orthostatic Hypotension 21 2.1 2.1 signal
505 Body Height Decreased 13 2.1 2.1 signal
506 Pain In Jaw 34 2.1 2.1 signal
507 Dysphonia 70 2.1 2.1 signal
508 Respiratory Tract Congestion 19 2.1 2.1 signal
509 Product Container Issue 10 2.1 2.1 signal
510 Condition Aggravated 358 2.1 2.1 signal
511 Dementia 33 2.1 2.1 signal
512 Dysphagia 112 2.1 2.1 signal
513 Pseudomonas Infection 10 2.1 2.1 signal
514 Cardiac Operation 10 2.1 2.1 signal
515 Temperature Intolerance 12 2.1 2.1 signal
516 Aortic Aneurysm 9 2.1 2.1 no signal
517 Tubulointerstitial Nephritis 22 2.0 2.1 signal
518 Product Administration Interrupted 9 2.0 2.0 no signal
519 Anhedonia 31 2.0 2.0 signal
520 Eating Disorder 25 2.0 2.0 signal
521 Low Density Lipoprotein Increased 9 2.0 2.0 no signal
522 Fatigue 905 2.0 2.1 signal
523 Platelet Count Decreased 124 2.0 2.0 signal
524 Leukocytosis 21 2.0 2.0 signal
525 Sinus Disorder 23 2.0 2.0 signal
526 Foot Fracture 22 2.0 2.0 signal
527 Renal Disorder 54 2.0 2.0 signal
528 Respiratory Syncytial Virus Infection 10 2.0 2.0 signal
529 Product Physical Issue 23 2.0 2.0 signal
530 Pollakiuria 48 2.0 2.0 signal
531 Immunosuppression 10 2.0 2.0 signal
532 Deep Vein Thrombosis 75 2.0 2.0 signal
533 Myalgia 195 2.0 2.0 signal
534 Therapy Non-responder 51 2.0 2.0 no signal
535 Hypophagia 29 2.0 2.0 no signal
536 Furuncle 9 2.0 2.0 no signal
537 Infusion Related Reaction 75 2.0 2.0 no signal
538 Thrombocytopenia 126 2.0 2.0 no signal
539 Blood Lactate Dehydrogenase Increased 18 2.0 2.0 no signal
540 Vomiting 527 2.0 2.0 no signal
541 Injection Site Extravasation 14 2.0 2.0 no signal
542 Transient Ischaemic Attack 38 2.0 2.0 no signal
543 Procedural Pain 31 2.0 2.0 no signal
544 Covid-19 197 1.9 2.0 no signal
545 Skin Haemorrhage 16 1.9 1.9 no signal
546 Lupus-like Syndrome 10 1.9 1.9 no signal
547 Muscle Disorder 9 1.9 1.9 no signal
548 Anaemia 211 1.9 1.9 no signal
549 Toothache 20 1.9 1.9 no signal
550 Feeding Disorder 22 1.9 1.9 no signal
551 Gastric Ulcer 21 1.9 1.9 no signal
552 Pain In Extremity 325 1.9 1.9 no signal
553 Fall 365 1.9 1.9 no signal
554 Taste Disorder 22 1.9 1.9 no signal
555 Product Use In Unapproved Indication 268 1.9 1.9 no signal
556 Ankle Fracture 17 1.9 1.9 no signal
557 Intervertebral Disc Protrusion 24 1.9 1.9 no signal
558 Pruritus Generalised 24 1.9 1.9 no signal
559 Premature Baby 33 1.9 1.9 no signal
560 Hepatic Failure 33 1.9 1.9 no signal
561 Gastric Disorder 38 1.9 1.9 no signal
562 Drug Intolerance 105 1.9 1.9 no signal
563 Dysgeusia 81 1.9 1.9 no signal
564 Fluid Retention 55 1.9 1.9 no signal
565 Localised Infection 26 1.9 1.9 no signal
566 Balance Disorder 93 1.9 1.9 no signal
567 Nodule 14 1.9 1.9 no signal
568 Fibromyalgia 26 1.9 1.9 no signal
569 Oral Pain 24 1.9 1.9 no signal
570 Increased Appetite 20 1.9 1.9 no signal
571 Blood Sodium Decreased 20 1.9 1.9 no signal
572 Premature Delivery 17 1.9 1.9 no signal
573 Toxic Epidermal Necrolysis 16 1.9 1.9 no signal
574 Unevaluable Event 80 1.8 1.9 no signal
575 Sensory Disturbance 17 1.8 1.8 no signal
576 Eczema 53 1.8 1.8 no signal
577 Heart Rate Increased 104 1.8 1.8 no signal
578 Gastrointestinal Haemorrhage 88 1.8 1.8 no signal
579 C-reactive Protein Increased 38 1.8 1.8 no signal
580 Autoimmune Disorder 10 1.8 1.8 no signal
581 Malignant Melanoma 14 1.8 1.8 no signal
582 Pharyngitis 13 1.8 1.8 no signal
583 Quality Of Life Decreased 14 1.8 1.8 no signal
584 Nausea 821 1.8 1.9 no signal
585 Neuralgia 25 1.8 1.8 no signal
586 Blood Cholesterol Increased 48 1.8 1.8 no signal
587 Sneezing 23 1.8 1.8 no signal
588 Staphylococcal Infection 34 1.8 1.8 no signal
589 Spinal Pain 12 1.8 1.8 no signal
590 Viral Infection 34 1.8 1.8 no signal
591 Chills 120 1.8 1.8 no signal
592 Kidney Infection 20 1.8 1.8 no signal
593 Skin Laceration 11 1.8 1.8 no signal
594 Chromaturia 23 1.8 1.8 no signal
595 Drug Reaction With Eosinophilia And Systemic Symptoms 26 1.8 1.8 no signal
596 Epistaxis 76 1.8 1.8 no signal
597 Laryngitis 11 1.8 1.8 no signal
598 Hypersomnia 29 1.8 1.8 no signal
599 Amnesia 66 1.8 1.8 no signal
600 Blood Urea Increased 17 1.8 1.8 no signal
601 Restlessness 37 1.8 1.8 no signal
602 Upper Gastrointestinal Haemorrhage 17 1.8 1.8 no signal
603 Skin Fissures 19 1.8 1.8 no signal
604 Pruritus 380 1.8 1.8 no signal
605 Joint Swelling 121 1.8 1.8 no signal
606 Spinal Fracture 20 1.8 1.8 no signal
607 Mucosal Inflammation 26 1.7 1.7 no signal
608 Blood Test Abnormal 14 1.7 1.7 no signal
609 Hot Flush 75 1.7 1.7 no signal
610 Emphysema 10 1.7 1.7 no signal
611 White Blood Cell Count Increased 38 1.7 1.7 no signal
612 Optic Neuritis 9 1.7 1.7 no signal
613 Pleural Effusion 60 1.7 1.7 no signal
614 Pulmonary Congestion 13 1.7 1.7 no signal
615 Flushing 100 1.7 1.7 no signal
616 Impaired Work Ability 21 1.7 1.7 no signal
617 Feeling Hot 60 1.7 1.7 no signal
618 Oral Herpes 19 1.7 1.7 no signal
619 Urosepsis 9 1.7 1.7 no signal
620 Blood Count Abnormal 15 1.7 1.7 no signal
621 International Normalised Ratio Increased 28 1.7 1.7 no signal
622 Bacterial Infection 18 1.7 1.7 no signal
623 Dermatitis Contact 11 1.7 1.7 no signal
624 Impaired Driving Ability 11 1.7 1.7 no signal
625 Renal Injury 29 1.7 1.7 no signal
626 Scratch 10 1.7 1.7 no signal
627 Cyst 12 1.7 1.7 no signal
628 Weight Increased 214 1.7 1.7 no signal
629 Pericardial Effusion 22 1.7 1.7 no signal
630 Eye Inflammation 9 1.7 1.7 no signal
631 Gingival Bleeding 13 1.7 1.7 no signal
632 Upper Limb Fracture 19 1.7 1.7 no signal
633 Spinal Disorder 9 1.7 1.7 no signal
634 Cardiomyopathy 14 1.7 1.7 no signal
635 Urinary Incontinence 28 1.6 1.7 no signal
636 Neutropenia 128 1.6 1.7 no signal
637 Impaired Healing 31 1.6 1.6 no signal
638 Vasculitis 11 1.6 1.6 no signal
639 Post Procedural Haemorrhage 11 1.6 1.6 no signal
640 Hypercholesterolaemia 9 1.6 1.6 no signal
641 Pulmonary Oedema 42 1.6 1.6 no signal
642 Joint Injury 20 1.6 1.6 no signal
643 Glaucoma 18 1.6 1.6 no signal
644 Pyrexia 322 1.6 1.6 no signal
645 Mass 13 1.6 1.6 no signal
646 Rib Fracture 19 1.6 1.6 no signal
647 Conjunctivitis 17 1.6 1.6 no signal
648 Bone Disorder 17 1.6 1.6 no signal
649 Musculoskeletal Stiffness 81 1.6 1.6 no signal
650 Discomfort 56 1.6 1.6 no signal
651 Pneumonia Aspiration 23 1.6 1.6 no signal
652 Dysuria 34 1.6 1.6 no signal
653 Drug Effect Less Than Expected 13 1.6 1.6 no signal
654 Product Use Issue 172 1.6 1.6 no signal
655 Hypertension 195 1.6 1.6 no signal
656 Migraine 87 1.6 1.6 no signal
657 Dermatitis 19 1.6 1.6 no signal
658 Malaise 403 1.6 1.6 no signal
659 Pallor 25 1.6 1.6 no signal
660 Metabolic Acidosis 29 1.6 1.6 no signal
661 Pulmonary Thrombosis 10 1.6 1.6 no signal
662 Eye Disorder 30 1.6 1.6 no signal
663 Headache 573 1.6 1.6 no signal
664 Renal Tubular Necrosis 9 1.6 1.6 no signal
665 Nervousness 48 1.6 1.6 no signal
666 Hospice Care 9 1.6 1.6 no signal
667 Dyspnoea 516 1.6 1.6 no signal
668 Neoplasm Progression 32 1.6 1.6 no signal
669 Swelling Face 59 1.6 1.6 no signal
670 Insomnia 241 1.6 1.6 no signal
671 Dry Mouth 73 1.6 1.6 no signal
672 Muscular Weakness 102 1.6 1.6 no signal
673 Skin Infection 10 1.6 1.6 no signal
674 Influenza Like Illness 74 1.6 1.6 no signal
675 Hyponatraemia 50 1.6 1.6 no signal
676 Eyelid Ptosis 9 1.5 1.5 no signal
677 Epilepsy 27 1.5 1.5 no signal
678 Haematoma 23 1.5 1.5 no signal
679 Hypoxia 31 1.5 1.5 no signal
680 Scab 10 1.5 1.5 no signal
681 Pancytopenia 49 1.5 1.5 no signal
682 Needle Issue 25 1.5 1.5 no signal
683 Coronary Artery Occlusion 12 1.5 1.5 no signal
684 Respiratory Distress 24 1.5 1.5 no signal
685 Movement Disorder 28 1.5 1.5 no signal
686 Tooth Loss 18 1.5 1.5 no signal
687 Arthropathy 48 1.5 1.5 no signal
688 Chest Pain 159 1.5 1.5 no signal
689 Product Dose Omission In Error 23 1.5 1.5 no signal
690 Septic Shock 37 1.5 1.5 no signal
691 Blood Creatinine Increased 56 1.5 1.5 no signal
692 Cardiac Failure Congestive 69 1.5 1.5 no signal
693 Syncope 85 1.5 1.5 no signal
694 Skin Discolouration 39 1.5 1.5 no signal
695 Dialysis 12 1.5 1.5 no signal
696 Burning Sensation 59 1.5 1.5 no signal
697 Poor Quality Sleep 18 1.5 1.5 no signal
698 Cardiogenic Shock 12 1.5 1.5 no signal
699 Blood Urine Present 16 1.5 1.5 no signal
700 Macular Degeneration 10 1.5 1.5 no signal
701 Lymphoma 13 1.5 1.5 no signal
702 Lower Limb Fracture 16 1.5 1.5 no signal
703 Pharyngeal Swelling 8 1.5 1.5 no signal
704 Cerebrovascular Accident 142 1.5 1.5 no signal
705 Ejection Fraction Decreased 13 1.5 1.5 no signal
706 Musculoskeletal Pain 44 1.5 1.5 no signal
707 Product Dose Omission Issue 236 1.4 1.5 no signal
708 Anxiety 236 1.4 1.5 no signal
709 Presyncope 20 1.4 1.4 no signal
710 Hypotension 165 1.4 1.4 no signal
711 Joint Range Of Motion Decreased 11 1.4 1.4 no signal
712 Blood Creatine Phosphokinase Increased 24 1.4 1.4 no signal
713 Lethargy 47 1.4 1.4 no signal
714 Melaena 18 1.4 1.4 no signal
715 Immunodeficiency 12 1.4 1.4 no signal
716 Throat Tightness 22 1.4 1.4 no signal
717 Depression 186 1.4 1.4 no signal
718 Gait Disturbance 156 1.4 1.4 no signal
719 Liver Disorder 36 1.4 1.4 no signal
720 Eye Swelling 30 1.4 1.4 no signal
721 Urinary Retention 27 1.4 1.4 no signal
722 Surgery 47 1.4 1.4 no signal
723 Secretion Discharge 10 1.4 1.4 no signal
724 Acute Hepatic Failure 11 1.4 1.4 no signal
725 Blood Pressure Abnormal 16 1.4 1.4 no signal
726 Stomatitis 49 1.4 1.4 no signal
727 Cardiomegaly 10 1.4 1.4 no signal
728 Intentional Dose Omission 22 1.4 1.4 no signal
729 Exposure During Pregnancy 50 1.4 1.4 no signal
730 Muscle Tightness 13 1.4 1.4 no signal
731 Hypoglycaemia 39 1.4 1.4 no signal
732 Palpitations 94 1.4 1.4 no signal
733 Bone Pain 47 1.4 1.4 no signal
734 Feeling Abnormal 192 1.4 1.4 no signal
735 Hypotonia 8 1.4 1.4 no signal
736 Aphasia 24 1.4 1.4 no signal
737 Treatment Noncompliance 43 1.4 1.4 no signal
738 Wound 22 1.4 1.4 no signal
739 Pain 486 1.4 1.4 no signal
740 Dyskinesia 32 1.4 1.4 no signal
741 Aphonia 11 1.4 1.4 no signal
742 Sluggishness 8 1.4 1.4 no signal
743 Hypoaesthesia 118 1.4 1.4 no signal
744 Cytokine Release Syndrome 15 1.4 1.4 no signal
745 Haematuria 27 1.4 1.4 no signal
746 Liver Injury 19 1.4 1.4 no signal
747 Helicobacter Infection 8 1.4 1.4 no signal
748 Chest Discomfort 80 1.4 1.4 no signal
749 Mental Impairment 19 1.4 1.4 no signal
750 Anaphylactic Reaction 43 1.4 1.4 no signal
751 Poor Quality Product Administered 8 1.4 1.4 no signal
752 Hepatitis 20 1.4 1.4 no signal
753 Skin Disorder 26 1.4 1.4 no signal
754 Neoplasm 9 1.4 1.4 no signal
755 Muscle Twitching 18 1.4 1.4 no signal
756 Dizziness 387 1.4 1.4 no signal
757 Renal Impairment 65 1.4 1.4 no signal
758 Eyelid Oedema 9 1.3 1.3 no signal
759 Blister 43 1.3 1.3 no signal
760 Respiratory Disorder 23 1.3 1.3 no signal
761 Pulmonary Embolism 73 1.3 1.3 no signal
762 Tremor 127 1.3 1.3 no signal
763 Deafness 20 1.3 1.3 no signal
764 Hereditary Angioedema 8 1.3 1.3 no signal
765 Bedridden 10 1.3 1.3 no signal
766 Confusional State 123 1.3 1.3 no signal
767 Joint Dislocation 8 1.3 1.3 no signal
768 Therapeutic Response Unexpected 34 1.3 1.3 no signal
769 Paraesthesia 119 1.3 1.3 no signal
770 Product Packaging Issue 7 1.3 1.3 no signal
771 Rash 326 1.3 1.3 no signal
772 Product Administration Error 15 1.3 1.3 no signal
773 Injection Site Haematoma 11 1.3 1.3 no signal
774 Breast Pain 8 1.3 1.3 no signal
775 Rash Erythematous 35 1.3 1.3 no signal
776 Nephropathy 7 1.3 1.3 no signal
777 Spinal Operation 9 1.3 1.3 no signal
778 Infection 107 1.3 1.3 no signal
779 Hair Texture Abnormal 10 1.3 1.3 no signal
780 Unresponsive To Stimuli 19 1.3 1.3 no signal
781 Aspiration 8 1.3 1.3 no signal
782 Cold Sweat 13 1.3 1.3 no signal
783 Urticaria 122 1.3 1.3 no signal
784 Body Temperature Increased 15 1.3 1.3 no signal
785 Bipolar Disorder 8 1.3 1.3 no signal
786 Hyperhidrosis 94 1.3 1.3 no signal
787 Dizziness Postural 7 1.3 1.3 no signal
788 Hepatic Function Abnormal 27 1.3 1.3 no signal
789 Febrile Neutropenia 48 1.3 1.3 no signal
790 Drug Level Increased 12 1.3 1.3 no signal
791 Ventricular Tachycardia 12 1.3 1.3 no signal
792 Dry Eye 35 1.3 1.3 no signal
793 Osteonecrosis Of Jaw 18 1.3 1.3 no signal
794 Ageusia 18 1.3 1.3 no signal
795 Drug Ineffective 946 1.3 1.3 no signal
796 Dysarthria 27 1.3 1.3 no signal
797 Decreased Immune Responsiveness 7 1.2 1.2 no signal
798 Hyperglycaemia 26 1.2 1.2 no signal
799 General Physical Health Deterioration 82 1.2 1.2 no signal
800 Inability To Afford Medication 7 1.2 1.2 no signal
801 Haematemesis 18 1.2 1.2 no signal
802 Injury 50 1.2 1.2 no signal
803 Hemiparesis 12 1.2 1.2 no signal
804 Intraocular Pressure Increased 9 1.2 1.2 no signal
805 Haemorrhage 73 1.2 1.2 no signal
806 Mobility Decreased 50 1.2 1.2 no signal
807 Activities Of Daily Living Impaired 14 1.2 1.2 no signal
808 Asthma 78 1.2 1.2 no signal
809 Gait Inability 23 1.2 1.2 no signal
810 Bone Density Decreased 22 1.2 1.2 no signal
811 Lung Disorder 34 1.2 1.2 no signal
812 Maternal Exposure During Pregnancy 61 1.2 1.2 no signal
813 Myelodysplastic Syndrome 10 1.2 1.2 no signal
814 Obesity 11 1.2 1.2 no signal
815 Vertigo 42 1.2 1.2 no signal
816 Hypokinesia 10 1.2 1.2 no signal
817 Product Prescribing Issue 14 1.2 1.2 no signal
818 Initial Insomnia 7 1.2 1.2 no signal
819 Sexual Dysfunction 8 1.2 1.2 no signal
820 Metastases To Liver 12 1.2 1.2 no signal
821 Palmar-plantar Erythrodysaesthesia Syndrome 16 1.2 1.2 no signal
822 Ear Discomfort 7 1.2 1.2 no signal
823 Head Discomfort 12 1.2 1.2 no signal
824 Complication Associated With Device 9 1.2 1.2 no signal
825 Hypersensitivity 126 1.2 1.2 no signal
826 Musculoskeletal Disorder 13 1.2 1.2 no signal
827 Lymphocyte Count Decreased 12 1.2 1.2 no signal
828 Local Swelling 12 1.2 1.2 no signal
829 Bradycardia 36 1.2 1.2 no signal
830 Diabetes Mellitus Inadequate Control 12 1.2 1.2 no signal
831 Fluid Overload 10 1.2 1.2 no signal
832 Back Disorder 11 1.2 1.2 no signal
833 Ventricular Extrasystoles 7 1.2 1.2 no signal
834 Loss Of Personal Independence In Daily Activities 32 1.2 1.2 no signal
835 Accident 8 1.2 1.2 no signal
836 Lacrimation Increased 20 1.2 1.2 no signal
837 Hunger 9 1.2 1.2 no signal
838 Road Traffic Accident 28 1.2 1.2 no signal
839 Adrenal Insufficiency 8 1.2 1.2 no signal
840 Speech Disorder 35 1.2 1.2 no signal
841 Tachypnoea 9 1.2 1.2 no signal
842 Fear 18 1.2 1.2 no signal
843 Lip Swelling 22 1.2 1.2 no signal
844 Alopecia 130 1.2 1.2 no signal
845 Hip Arthroplasty 10 1.1 1.1 no signal
846 Shock 15 1.1 1.1 no signal
847 Hepatitis C 8 1.1 1.1 no signal
848 Diplopia 17 1.1 1.1 no signal
849 Foetal Exposure During Pregnancy 53 1.1 1.1 no signal
850 Drug Effective For Unapproved Indication 19 1.1 1.1 no signal
851 Agranulocytosis 12 1.1 1.1 no signal
852 Dysstasia 19 1.1 1.1 no signal
853 Memory Impairment 89 1.1 1.1 no signal
854 Device Occlusion 9 1.1 1.1 no signal
855 Tendon Rupture 8 1.1 1.1 no signal
856 Incorrect Dose Administered 145 1.1 1.1 no signal
857 Respiratory Failure 47 1.1 1.1 no signal
858 Blood Glucose Decreased 31 1.1 1.1 no signal
859 Sleep Disorder 45 1.1 1.1 no signal
860 Acute Myocardial Infarction 19 1.1 1.1 no signal
861 Leukopenia 32 1.1 1.1 no signal
862 Pharyngeal Oedema 10 1.1 1.1 no signal
863 Vision Blurred 87 1.1 1.1 no signal
864 Sinus Tachycardia 9 1.1 1.1 no signal
865 Lung Infection 10 1.1 1.1 no signal
866 Cyanosis 10 1.1 1.1 no signal
867 Poisoning 8 1.1 1.1 no signal
868 Arrhythmia 30 1.1 1.1 no signal
869 Transaminases Increased 14 1.1 1.1 no signal
870 Pain Of Skin 17 1.1 1.1 no signal
871 Hallucination, Auditory 10 1.1 1.1 no signal
872 Subdural Haematoma 9 1.1 1.1 no signal
873 Paraesthesia Oral 9 1.1 1.1 no signal
874 Angina Pectoris 18 1.1 1.1 no signal
875 Erythema 128 1.1 1.1 no signal
876 Knee Arthroplasty 13 1.1 1.1 no signal
877 Drug Hypersensitivity 121 1.1 1.1 no signal
878 Therapy Change 6 1.1 1.1 no signal
879 Lower Respiratory Tract Infection 28 1.1 1.1 no signal
880 Thirst 11 1.1 1.1 no signal
881 Ischaemic Stroke 11 1.1 1.1 no signal
882 Internal Haemorrhage 7 1.1 1.1 no signal
883 Myocardial Ischaemia 7 1.1 1.1 no signal
884 Feeling Cold 17 1.1 1.1 no signal
885 Therapy Interrupted 42 1.1 1.1 no signal
886 Immune System Disorder 8 1.1 1.1 no signal
887 Depressed Mood 32 1.1 1.1 no signal
888 Photosensitivity Reaction 10 1.1 1.1 no signal
889 Delirium 21 1.1 1.1 no signal
890 Therapy Cessation 31 1.1 1.1 no signal
891 Myocardial Infarction 106 1.1 1.1 no signal
892 Visual Impairment 74 1.0 1.0 no signal
893 Haemorrhage Intracranial 9 1.0 1.0 no signal
894 Swelling 56 1.0 1.0 no signal
895 Injection Site Mass 22 1.0 1.0 no signal
896 Injection Site Bruising 47 1.0 1.0 no signal
897 Motor Dysfunction 6 1.0 1.0 no signal
898 Product Prescribing Error 14 1.0 1.0 no signal
899 Photophobia 11 1.0 1.0 no signal
900 Ataxia 7 1.0 1.0 no signal
901 Injection Site Warmth 12 1.0 1.0 no signal
902 Glossodynia 13 1.0 1.0 no signal
903 Adverse Drug Reaction 52 1.0 1.0 no signal
904 Peripheral Coldness 8 1.0 1.0 no signal
905 Therapeutic Response Decreased 35 1.0 1.0 no signal
906 Acute Myeloid Leukaemia 9 1.0 1.0 no signal
907 Dry Skin 76 1.0 1.0 no signal
908 Prostatic Specific Antigen Increased 8 1.0 1.0 no signal
909 Petechiae 6 1.0 1.0 no signal
910 Disease Progression 68 1.0 1.0 no signal
911 Eye Pruritus 19 1.0 1.0 no signal
912 Rash Generalised 15 1.0 1.0 no signal
913 Syringe Issue 10 1.0 1.0 no signal
914 Pharmaceutical Product Complaint 15 1.0 1.0 no signal
915 Loss Of Consciousness 73 1.0 1.0 no signal
916 Inappropriate Schedule Of Drug Administration 41 1.0 1.0 no signal
917 Renal Pain 6 1.0 1.0 no signal
918 Therapeutic Product Effect Incomplete 40 1.0 1.0 no signal
919 Tooth Extraction 7 1.0 1.0 no signal
920 Dermatitis Allergic 7 1.0 1.0 no signal
921 Malignant Neoplasm Progression 57 1.0 1.0 no signal
922 Cognitive Disorder 26 1.0 1.0 no signal
923 Bronchospasm 8 1.0 1.0 no signal
924 Product Dose Omission 37 1.0 1.0 no signal
925 Hair Colour Changes 7 1.0 1.0 no signal
926 Glycosylated Haemoglobin Increased 14 1.0 1.0 no signal
927 Drug Interaction 88 1.0 1.0 no signal
928 Rhabdomyolysis 23 1.0 1.0 no signal
929 Multiple Sclerosis Relapse 38 1.0 1.0 no signal
930 Diabetes Mellitus 42 1.0 1.0 no signal
931 Treatment Failure 45 1.0 1.0 no signal
932 Femur Fracture 17 1.0 1.0 no signal
933 Somnolence 110 1.0 1.0 no signal
934 Abortion Spontaneous 22 1.0 1.0 no signal
935 Injection Site Nodule 6 1.0 1.0 no signal
936 Blood Glucose Fluctuation 6 1.0 1.0 no signal
937 Tuberculosis 7 0.9 0.9 no signal
938 Eye Pain 30 0.9 0.9 no signal
939 Neutrophil Count Decreased 22 0.9 0.9 no signal
940 Hepatotoxicity 12 0.9 0.9 no signal
941 Injection Site Pruritus 36 0.9 0.9 no signal
942 Blood Glucose Abnormal 10 0.9 0.9 no signal
943 Hospitalisation 82 0.9 0.9 no signal
944 Haemoptysis 15 0.9 0.9 no signal
945 Colon Cancer 8 0.9 0.9 no signal
946 Hypoacusis 23 0.9 0.9 no signal
947 Ocular Hyperaemia 25 0.9 0.9 no signal
948 Injection Site Erythema 66 0.9 0.9 no signal
949 Deformity 5 0.9 0.9 no signal
950 Face Oedema 9 0.9 0.9 no signal
951 Cardiac Arrest 44 0.9 0.9 no signal
952 Leukaemia 5 0.9 0.9 no signal
953 Injection Site Haemorrhage 42 0.9 0.9 no signal
954 Coronary Artery Disease 16 0.9 0.9 no signal
955 Disease Recurrence 25 0.9 0.9 no signal
956 Injection Site Pain 159 0.9 0.9 no signal
957 Drug Exposure During Pregnancy 18 0.9 0.9 no signal
958 Multiple Sclerosis 25 0.9 0.9 no signal
959 Pneumonitis 14 0.9 0.9 no signal
960 Tachycardia 46 0.9 0.9 no signal
961 Sinus Bradycardia 5 0.9 0.9 no signal
962 Emotional Disorder 16 0.9 0.9 no signal
963 Mood Altered 14 0.9 0.9 no signal
964 Injection Site Swelling 39 0.9 0.9 no signal
965 Parkinsonism 5 0.9 0.9 no signal
966 Drug Effect Decreased 28 0.9 0.9 no signal
967 Expired Product Administered 17 0.9 0.9 no signal
968 Cardiac Disorder 48 0.9 0.9 no signal
969 Caesarean Section 6 0.9 0.9 no signal
970 Acute Respiratory Distress Syndrome 9 0.9 0.9 no signal
971 Brain Injury 5 0.9 0.9 no signal
972 Vaginal Discharge 5 0.9 0.9 no signal
973 Blood Glucose Increased 94 0.9 0.9 no signal
974 Interstitial Lung Disease 24 0.9 0.9 no signal
975 Seizure 57 0.9 0.9 no signal
976 Neoplasm Malignant 33 0.9 0.9 no signal
977 Pelvic Pain 9 0.9 0.9 no signal
978 Injection Site Rash 15 0.9 0.9 no signal
979 Skin Exfoliation 41 0.9 0.9 no signal
980 Hepatocellular Injury 7 0.9 0.9 no signal
981 Incorrect Drug Administration Duration 14 0.9 0.9 no signal
982 Eye Discharge 5 0.9 0.9 no signal
983 Libido Decreased 6 0.8 0.8 no signal
984 Folliculitis 5 0.8 0.8 no signal
985 Muscle Spasticity 6 0.8 0.8 no signal
986 Suicidal Ideation 44 0.8 0.8 no signal
987 Nervous System Disorder 15 0.8 0.8 no signal
988 Disorientation 19 0.8 0.8 no signal
989 Full Blood Count Abnormal 5 0.8 0.8 no signal
990 Type 2 Diabetes Mellitus 16 0.8 0.8 no signal
991 Medication Error 26 0.8 0.8 no signal
992 Ankylosing Spondylitis 6 0.8 0.8 no signal
993 Mental Disorder 20 0.8 0.8 no signal
994 Device Issue 40 0.8 0.8 no signal
995 Product Packaging Quantity Issue 5 0.8 0.8 no signal
996 Disability 9 0.8 0.8 no signal
997 Thyroid Disorder 7 0.8 0.8 no signal
998 Osteonecrosis 15 0.8 0.8 no signal
999 Delusion 7 0.8 0.8 no signal
1000 Therapeutic Product Effect Decreased 20 0.8 0.8 no signal
1001 Swollen Tongue 14 0.8 0.8 no signal
1002 Myocarditis 5 0.8 0.8 no signal
1003 Mood Swings 14 0.8 0.8 no signal
1004 Crying 16 0.8 0.8 no signal
1005 Extrapyramidal Disorder 11 0.8 0.8 no signal
1006 Drug Effect Incomplete 16 0.8 0.8 no signal
1007 Abnormal Dreams 12 0.8 0.8 no signal
1008 Gastric Haemorrhage 5 0.8 0.8 no signal
1009 Psoriasis 56 0.7 0.7 no signal
1010 Metastases To Bone 7 0.7 0.7 no signal
1011 Coordination Abnormal 6 0.7 0.7 no signal
1012 Grand Mal Convulsion 4 0.7 0.7 no signal
1013 Madarosis 5 0.7 0.7 no signal
1014 Hallucination 32 0.7 0.7 no signal
1015 Lymphopenia 6 0.7 0.7 no signal
1016 Proteinuria 8 0.7 0.7 no signal
1017 Cytomegalovirus Infection 7 0.7 0.7 no signal
1018 Polyneuropathy 5 0.7 0.7 no signal
1019 Acne 32 0.7 0.7 no signal
1020 Myoclonus 5 0.7 0.7 no signal
1021 Cytopenia 5 0.7 0.7 no signal
1022 Muscle Rigidity 5 0.7 0.7 no signal
1023 Visual Acuity Reduced 14 0.7 0.7 no signal
1024 Diabetic Ketoacidosis 10 0.7 0.7 no signal
1025 Anosmia 6 0.7 0.7 no signal
1026 Affect Lability 4 0.7 0.7 no signal
1027 Eye Irritation 23 0.7 0.7 no signal
1028 Emotional Distress 50 0.7 0.7 no signal
1029 Drug Dose Omission 69 0.7 0.7 no signal
1030 Panic Attack 15 0.7 0.7 no signal
1031 Dystonia 8 0.7 0.7 no signal
1032 Death 353 0.7 0.7 no signal
1033 Product Quality Issue 55 0.7 0.7 no signal
1034 Rheumatoid Arthritis 45 0.7 0.7 no signal
1035 Peritonitis Bacterial 4 0.7 0.7 no signal
1036 Pregnancy 8 0.7 0.7 no signal
1037 Ill-defined Disorder 24 0.7 0.7 no signal
1038 Hypothermia 4 0.7 0.7 no signal
1039 Incorrect Product Administration Duration 8 0.7 0.7 no signal
1040 Agitation 29 0.7 0.7 no signal
1041 Skin Burning Sensation 28 0.7 0.7 no signal
1042 Blindness 16 0.7 0.7 no signal
1043 Irritability 23 0.7 0.7 no signal
1044 Cardio-respiratory Arrest 16 0.7 0.7 no signal
1045 Incorrect Product Storage 5 0.7 0.7 no signal
1046 Sars-cov-2 Test Positive 5 0.7 0.7 no signal
1047 Lactic Acidosis 12 0.7 0.7 no signal
1048 Sleep Disorder Due To A General Medical Condition 6 0.6 0.6 no signal
1049 Adverse Event 34 0.6 0.6 no signal
1050 Ocular Discomfort 4 0.6 0.6 no signal
1051 Feeling Jittery 7 0.6 0.6 no signal
1052 Contraindicated Product Administered 11 0.6 0.6 no signal
1053 Cerebral Haemorrhage 13 0.6 0.6 no signal
1054 Multiple Fractures 6 0.6 0.6 no signal
1055 Prescribed Overdose 7 0.6 0.6 no signal
1056 Cardiac Failure 29 0.6 0.6 no signal
1057 Exposure Via Skin Contact 8 0.6 0.6 no signal
1058 Tardive Dyskinesia 10 0.6 0.6 no signal
1059 Metastases To Lung 4 0.6 0.6 no signal
1060 Pancreatic Carcinoma 10 0.6 0.6 no signal
1061 Pulmonary Arterial Hypertension 5 0.6 0.6 no signal
1062 Bone Marrow Failure 7 0.6 0.6 no signal
1063 Multi-organ Failure 6 0.6 0.6 no signal
1064 Peritonitis 7 0.6 0.6 no signal
1065 Coma 16 0.6 0.6 no signal
1066 Electrocardiogram Qt Prolonged 12 0.6 0.6 no signal
1067 Disturbance In Attention 18 0.6 0.6 no signal
1068 Underdose 24 0.6 0.6 no signal
1069 Hepatic Cytolysis 4 0.6 0.6 no signal
1070 Skin Irritation 15 0.6 0.6 no signal
1071 Injection Site Discolouration 4 0.6 0.6 no signal
1072 Fracture 6 0.6 0.6 no signal
1073 Injection Site Irritation 4 0.6 0.6 no signal
1074 Anaphylactic Shock 8 0.5 0.5 no signal
1075 Systemic Lupus Erythematosus 11 0.5 0.5 no signal
1076 Intentional Product Misuse 27 0.5 0.5 no signal
1077 Erectile Dysfunction 8 0.5 0.5 no signal
1078 Convulsion 18 0.5 0.5 no signal
1079 Knee Operation 3 0.5 0.5 no signal
1080 Injection Site Induration 4 0.5 0.5 no signal
1081 Breast Cancer 29 0.5 0.5 no signal
1082 Vaginal Haemorrhage 13 0.5 0.5 no signal
1083 Adverse Reaction 4 0.5 0.5 no signal
1084 Prostate Cancer 24 0.5 0.5 no signal
1085 Akathisia 4 0.5 0.5 no signal
1086 Wrong Technique In Product Usage Process 59 0.5 0.5 no signal
1087 Injection Site Reaction 20 0.5 0.5 no signal
1088 Lung Neoplasm Malignant 12 0.5 0.5 no signal
1089 Drug Toxicity 4 0.5 0.5 no signal
1090 Injection Site Urticaria 7 0.5 0.5 no signal
1091 Nightmare 10 0.5 0.5 no signal
1092 Withdrawal Syndrome 12 0.5 0.5 no signal
1093 Blindness Unilateral 4 0.5 0.5 no signal
1094 Device Malfunction 19 0.5 0.5 no signal
1095 Abasia 7 0.5 0.5 no signal
1096 Synovitis 5 0.5 0.5 no signal
1097 Meningioma 4 0.5 0.5 no signal
1098 Bone Loss 4 0.5 0.5 no signal
1099 Serotonin Syndrome 5 0.5 0.5 no signal
1100 Drug Prescribing Error 5 0.4 0.4 no signal
1101 Depressed Level Of Consciousness 10 0.4 0.4 no signal
1102 Extra Dose Administered 10 0.4 0.4 no signal
1103 Renal Cancer 12 0.4 0.4 no signal
1104 Psoriatic Arthropathy 10 0.4 0.4 no signal
1105 Injury Associated With Device 5 0.4 0.4 no signal
1106 Accidental Overdose 9 0.4 0.4 no signal
1107 Respiratory Depression 3 0.4 0.4 no signal
1108 Wrong Technique In Drug Usage Process 9 0.4 0.4 no signal
1109 Intentional Drug Misuse 5 0.4 0.4 no signal
1110 Device Use Issue 4 0.4 0.4 no signal
1111 Product Dispensing Error 5 0.4 0.4 no signal
1112 Dysmenorrhoea 3 0.4 0.4 no signal
1113 Abnormal Behaviour 9 0.4 0.4 no signal
1114 No Adverse Event 40 0.4 0.4 no signal
1115 Drug Administration Error 7 0.4 0.4 no signal
1116 Breast Cancer Female 6 0.4 0.4 no signal
1117 Overdose 48 0.4 0.4 no signal
1118 Application Site Rash 3 0.4 0.4 no signal
1119 Device Breakage 8 0.4 0.4 no signal
1120 Device Failure 3 0.3 0.3 no signal
1121 Product Preparation Error 4 0.3 0.3 no signal
1122 Incorrect Route Of Drug Administration 7 0.3 0.3 no signal
1123 Aggression 9 0.3 0.3 no signal
1124 Hepatic Cancer 4 0.3 0.3 no signal
1125 Toxicity To Various Agents 27 0.3 0.3 no signal
1126 Incorrect Dose Administered By Device 4 0.3 0.3 no signal
1127 Gastric Cancer 4 0.3 0.3 no signal
1128 Application Site Erythema 4 0.3 0.3 no signal
1129 Device Difficult To Use 10 0.3 0.3 no signal
1130 Product Storage Error 13 0.3 0.3 no signal
1131 Accidental Exposure To Product 15 0.3 0.3 no signal
1132 Completed Suicide 12 0.2 0.2 no signal
1133 Device Leakage 6 0.2 0.2 no signal
1134 Dermatitis Atopic 7 0.2 0.2 no signal
1135 Application Site Pruritus 3 0.2 0.2 no signal
1136 Product Complaint 3 0.2 0.2 no signal
1137 Bladder Cancer 7 0.2 0.2 no signal
1138 Device Use Error 4 0.2 0.2 no signal
1139 Device Dislocation 5 0.2 0.2 no signal
1140 Device Delivery System Issue 3 0.2 0.2 no signal
1141 Drug Withdrawal Syndrome 10 0.2 0.2 no signal
1142 Intentional Overdose 7 0.2 0.2 no signal
1143 Myelosuppression 3 0.2 0.2 no signal
1144 Product Adhesion Issue 3 0.1 0.1 no signal
1145 Drug Dose Omission By Device 6 0.1 0.1 no signal