Reaction

Chronic Kidney Disease-Mineral And Bone Disorder reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,062 reports · 312 co-occurring drugs

As of the last recalculation, Chronic Kidney Disease-Mineral And Bone Disorder appears in 1,062 FAERS reports alongside 312 co-occurring drug terms. The strongest observed disproportionality signal is ESOMEPRAZOLE MAGNESIUM (PRR 187.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Esomeprazole Magnesium	723	187.6	188.1
Sevelamer Carbonate	86	159.5	160.7
Calcitriol Capsules 0.25 Mcg	128	142.2	143.1
Calcitriol Capsules 0.5 Mcg	128	142.2	143.1
Calcitriol	128	140.5	141.4
Cephalexin	125	128.2	128.9
Lansoprazole	542	120.8	121.1
Omeprazole Magnesium	753	111.0	111.2
Dexlansoprazole	180	101.6	102.1
Calcium Carbonate	246	93.1	93.5
Benzonatate	71	90.2	90.5
Cimetidine	42	89.0	89.3
Labetalol	48	73.9	74.1
Polyethylene Glycol	39	73.3	73.5
Mupirocin	48	73.0	73.3
Pantoprazole Sodium	365	73.0	73.2
Mupirocin Calcium	48	71.6	71.9
Clonidine	147	65.1	65.3
Meclizine Hcl 12.5Mg	42	62.8	63.0
Meclizine Hcl 25Mg	42	62.8	63.0
Meclizine Hcl 12.5 Mg	42	62.8	63.0
Meclizine Hcl 25 Mg	42	62.8	63.0
Epoetin Alfa	36	61.6	61.8
Iron Sucrose	29	61.3	61.4
Gentamicin	39	60.6	60.8
Metolazone	32	57.5	57.7
Amoxicillin	185	57.3	57.4
Sucralfate Oral	39	55.8	55.9
Chlorthalidone	32	55.7	55.8
Sucralfate Oral Suspension	39	55.6	55.8
Meclizine	44	55.1	55.2
Sodium Bicarbonate	61	54.5	54.6
Sodium Bicarbonate Injection,	61	54.5	54.6
Terazosin Hydrochloride	24	54.1	54.2
Cyclobenzaprine	121	53.5	53.6
Gentamicin Sulfate	41	52.9	53.0
Ciprofolxacin	163	52.5	52.6
Ciprofloxacin Tablets	163	52.5	52.6
Famotidine	241	51.7	51.8
Paricalcitol	35	50.2	50.3
Sucralfate	58	50.1	50.2
Clotrimazole	30	49.2	49.4
Dextrose	32	49.1	49.2
Drs. Clotrimazole	28	48.7	48.9
Family Wellness Clotrimazole	28	48.7	48.9
Clotrimazole Topical	28	48.7	48.8
Dextrose Monohydrate	32	48.4	48.5
Meclizine Hydrochloride	46	48.1	48.2
Ciprofloxacin	186	47.9	48.0
Isosorbide Mononitrate	48	47.5	47.6
Ciprofloxacin Hydrochloride	192	47.0	47.1
Clindamycin	64	47.0	47.1
Isosorbide Dinitrate	44	46.0	46.1
Doxepin	23	45.4	45.5
Doxyclycline Hyclate	38	45.3	45.4
Magnesium Hydroxide	30	44.9	45.0
Ferrous Sulfate	101	43.5	43.5
Carisoprodol	40	42.7	42.7
Tizanidine	49	42.1	42.2
Dolutegravir Sodium	19	42.0	42.1
Bisacodyl Suppositories	27	41.9	42.0
Biscodyl	27	41.6	41.6
Methocarbamol Tablets	34	41.1	41.2
Nystatin	54	40.7	40.8
Nitroglycerin	101	40.7	40.8
Clindamycin Phosphate	65	40.6	40.6
Nystatin Ointment	51	40.0	40.1
Nystatin Cream	51	39.9	40.0
Doxycycline Hyclate	119	38.8	38.9
Nifedipine	86	38.8	38.8
Doxycycline	120	38.7	38.8
Bisacodyl	27	38.6	38.6
Lisinopril	386	38.3	38.3
Doxepin Hydrochloride	24	38.1	38.2
Docusate Sodium - Sennosides	59	37.9	38.0
Indomethacin	25	37.8	37.9
Methocarbamol	42	37.7	37.8
Carvedilol	210	37.7	37.7
Rabeprazole Sodium	50	37.7	37.7
Amlodipine Besylate And Benazepril Hydrochloride	17	36.7	36.7
Terbinafine Hydrochloride	16	35.8	35.9
Dicyclomine Hydrochloride	25	35.2	35.3
Abacavir Sulfate	17	34.7	34.8
Cinacalcet Hydrochloride	75	33.9	33.9
Erythromycin	31	33.3	33.4
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	15	33.1	33.2
Gemfibrozil	25	33.0	33.1
Nitrofurantoin	27	32.9	33.0
Nitrofurantoin (Monohydrate/Macrocrystals)	27	32.5	32.5
Doxazosin	44	32.1	32.2
Colchicine	41	31.7	31.7
Torsemide	51	31.6	31.7
Levofloxacin	89	31.5	31.5
Levofloxacin In 5% Dextrose	89	31.5	31.5
Cefuroxime	18	31.4	31.4
Insulin Aspart	96	31.2	31.2
Glipizide	89	31.2	31.2
Docusate Sodium	84	30.9	30.9
Hyoscyamine Sulfate	14	30.3	30.3
Ropinirole	23	30.0	30.0
Ketoconazole Foam	22	29.8	29.8
Ketoconazole Cream, 2%	22	29.6	29.7
Meloxicam	81	29.5	29.5
Lubiprostone	14	29.4	29.4
Azithromycin	57	29.3	29.3
Azithromycin Dihydrate	81	29.2	29.3
Azithromycin Monohydrate	58	28.8	28.8
Valganciclovir	27	28.8	28.8
Valganciclovir Hydrochloride	27	28.8	28.8
Ondansetron	139	28.5	28.6
Ondansetron Tablets	139	28.5	28.6
Promethazine Hydrochloride	26	28.1	28.1
Emtricitabine And Tenofovir Alafenamide	16	28.1	28.1
Tenofovir Disoproxil Fumarate	45	27.8	27.9
Moxifloxacin Hydrochloride	28	27.8	27.8
Ezetimibe And Simvastatin	21	27.6	27.6
Niacin	16	27.4	27.4
Furosemide	367	26.9	26.9
Temazepam	49	26.7	26.7
Ketoconazole	23	26.6	26.6
Amlodipine Besylate	168	26.5	26.5
Lidicaine	62	26.3	26.3
Burn Relief	62	26.3	26.3
Lidocaine Hydrochloride And Epinephrine	62	26.3	26.3
Metronidazole Topical	60	26.1	26.1
Cefazolin	12	26.1	26.1
Ondansetron Hydrochloride	142	26.1	26.1
Doxazosin Mesylate	46	26.1	26.1
Lidocaine, Menthol	62	26.0	26.0
Glyburide	31	25.8	25.9
Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	13	25.6	25.7
Minocycline	15	25.6	25.6
Tizanidine Hydrochloride	23	25.5	25.5
Emtricitabine And Tenofovir Disoproxil Fumarate	56	25.3	25.4
Fenofibrate	44	25.3	25.4
Metoroprolol Tartrate	79	25.3	25.3
Losartan	185	24.9	24.9
Lidocaine Hydrochloride And Epinephrine Bitartrate	63	24.5	24.6
Amoxicillin And Clavulanate Potassium	33	24.5	24.6
Docusate Sodium 100Mg	29	24.4	24.4
Lidocaine 4%	62	23.6	23.6
Naproxen	87	23.6	23.6
Lovastatin	30	23.5	23.6
Oxycodone And Acetaminophen Tablets	14	23.3	23.3
Lisinopril And Hydrochlorothiazide	12	23.3	23.3
Guaifenesin	35	23.2	23.2
Ciprofloxacin Hydrochloride And Hydrocortisone	24	23.1	23.1
Loratadine Oral	55	23.1	23.1
Glimepiride	44	23.0	23.1
Lisinopril And Hydrochlorothiazide Tablets	9	22.6	22.7
Darunavir	17	22.4	22.4
Pioglitazone	47	22.2	22.3
Metronidazole	68	22.2	22.2
Bumetanide	29	22.1	22.1
Lidocaine	62	22.1	22.1
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	20	22.0	22.0
Esomeprazole Magnesium Capsule, Delayed Release	16	21.9	21.9
Esomeprazole Magnesium Delayed Release Capsules	16	21.9	21.9
Linagliptin	20	21.9	21.9
Esomeprazole Magnesium Dihydrate	16	21.8	21.9
Lidocaine Hydrochloride	63	21.7	21.7
Tobramycin Solution	13	21.5	21.5
Magnesium Oxide	44	21.5	21.5
Primidone	11	21.4	21.4
Oseltamivir Phosphate	26	21.4	21.4
Simvastatin	219	21.4	21.4
Fluticasone Propionate	125	21.3	21.3
Moxifloxacin	15	21.2	21.2
Sennosides 8.6 Mg Tablets	22	21.0	21.0
Senna	22	20.9	20.9
Tobramycin Sulfate	13	20.8	20.8
Zolpidem Tartrate	127	20.8	20.8
Potassium Chloride	109	20.8	20.8
Vancomycin	58	20.7	20.8
Lactulose	39	20.7	20.7
Oxybutynin	30	20.6	20.7
Hydroxyzine	48	20.6	20.6
Standardized Senna Concentrate	13	20.5	20.5
Fexofenadine	17	20.5	20.5
Metoprolol	214	20.4	20.4
Esomeprazole	61	20.4	20.4
Fluconazole	68	20.2	20.3
Atropine Sulfate	11	20.2	20.2
Allopurinol	140	20.1	20.1
Amlodipine	221	20.0	20.0
Metoprolol Tartrate	223	20.0	20.0
Oseltamivir	8	19.8	19.9
Tolterodine Tartrate	9	19.8	19.8
Cefazolin Sodium	12	19.7	19.7
Ibuprofen Capsule	167	19.3	19.3
Ibuprofen Tablet, Film Coated	167	19.3	19.3
Ibupfrofen	167	19.3	19.3
Ibuprofen Tablets Usp, 200Mg	167	19.3	19.3
Ibuprofen Oral	167	19.3	19.3
Ibuprofen Capsules 200 Mg	167	19.3	19.3
Ibuprofen 200 Mg	167	19.3	19.3
Ibuprofen 200Mg	167	19.3	19.3
Metoprolol Succinate	79	19.2	19.2
Ergocalciferol	281	19.1	19.1
Senna Leaf	22	19.1	19.1
Atropine	8	19.1	19.1
Human Insulin	12	19.0	19.1
Mometasone Furoate	39	19.0	19.0
Aspirin 325 Mg	343	18.9	18.9
Aspirin 81 Mg	343	18.9	18.9
Gabapentin	268	18.9	18.9
Hydrochlorothiazide	124	18.8	18.8
Vancomycin Hydrochloride	59	18.5	18.5
Aspirin	349	18.5	18.5
Desloratadine	10	18.4	18.5
Daspone	9	18.3	18.3
Dapsone Gel, 5%	9	18.3	18.3
Sennosides	27	18.1	18.2
Cholestyramine	11	18.0	18.0
Oxycodone And Acetaminophen	21	18.0	18.0
Potassium Chloride, Dextrose Monohydrate	79	18.0	18.0
Potassium Chloride Oral	79	18.0	18.0
Potassium Chloride Extended-Release	79	18.0	18.0
Acetaminophen And Codeine	11	17.9	17.9
Febuxostat	15	17.8	17.8
Losartan Potassium	67	17.7	17.7
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	127	17.5	17.5
Metoprolol Tartrate Injection	147	17.5	17.5
Diphenoxylate Hydrochloride And Atropine Sulfate	12	17.4	17.4
Clopidogrel	150	17.1	17.1
Losartan Potassium And Hydrochlorothiazide	10	17.0	17.0
Metoclopramide Hydrochloride	63	16.9	17.0
Mycophenolic Acid	27	16.9	17.0
Valsartan	84	16.9	16.9
Ranitidine	149	16.9	16.9
Raltegravir	14	16.8	16.8
Brimonidine Tartrate	15	16.7	16.7
Clopidogrel Bisulfate	81	16.7	16.7
Dapsone	9	16.7	16.7
Azelastine	15	16.6	16.6
Ritonavir	24	16.4	16.5
Omeprazole	230	16.4	16.4
Midazolam Hydrochloride	22	16.3	16.3
Psyllium Husk	8	16.0	16.0
Midazolam	20	15.8	15.8
Oxybutynin Chloride	7	15.7	15.8
Loratadine	80	15.7	15.7
Lamivudine	24	15.6	15.6
Atazanavir	11	15.1	15.2
Naproxen Sodium	100	15.0	15.0
Quinapril Hydrochloride	6	15.0	15.0
Butalbital, Acetaminophen, And Caffeine	8	14.8	14.8
Metoclopramide	40	14.8	14.8
Valganciclovir Hydrochloride Powder,	9	14.6	14.6
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	36	14.6	14.6
Bupropion	32	14.5	14.5
Diazepam Oral Solution (Concentrate)	62	14.4	14.4
Diazepam Oral	62	14.4	14.4
Paroxetine Hydrochloride Hemihydrate	24	14.4	14.4
Methoxy Polyethylene Glycol-Epoetin Beta	8	14.3	14.3
Alprazolam	132	14.2	14.2
Oxycodone	121	14.2	14.2
Piperacillin Sodium And Tazobactam Sodium	14	14.2	14.2
Paroxetine	24	14.1	14.1
Minoxidil Foam 5% (Womens)	23	13.9	14.0
Olmesartan Medoxomil	25	13.9	13.9
Sitagliptin	49	13.9	13.9
Icosapent Ethyl	6	13.9	13.9
Prasugrel Hydrochloride	7	13.6	13.6
Fluticasone Propionate And Salmeterol Xinafoate	40	13.5	13.5
Hydroxyzine Hydrochloride	9	13.5	13.5
Hydroxyzine Hydrochloride Oral	9	13.5	13.5
Erythropoietin	14	13.5	13.5
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	14	13.5	13.5
Naproxen Sodium, Pseudoephedrine Hydrochloride	14	13.5	13.5
Umeclidinium	6	13.2	13.2
Nicotine Polacrilex Mini	10	13.2	13.2
Nicotine Polarilex	10	13.2	13.2
Pravastatin Sodium	13	13.0	13.0
Atorvastatin Calcium	143	12.9	12.9
Heparin Sodium	9	12.9	12.9
Mycophenilic Acid	13	12.4	12.4
Nebivolol Hydrochloride	21	12.4	12.4
Insulin Glargine	135	12.1	12.1
Insulin Lispro	78	11.9	11.9
Zidovudine	8	11.8	11.8
Valsartan And Hydrochlorothiazide	8	11.6	11.6
Clobetasol Propionate Ointment Usp, 0.05%	6	11.5	11.5
Prochlorperazine	16	11.5	11.5
Clobetasol Propionate	6	11.4	11.4
Methadone	23	10.7	10.7
Tobramycin	13	10.7	10.7
Conjugated Estrogens	31	10.7	10.7
Bupivacaine	5	10.5	10.5
Acetaminophen, Aspirin (Nsaid) And Caffeine	9	10.5	10.5
Linaclotide	14	10.4	10.4
Oxycodone Hydrochloride And Acetaminophen	50	10.4	10.4
Minoxidil	23	10.2	10.2
Estrogens, Conjugated	30	10.2	10.2
Insulin Degludec	12	10.1	10.1
Sildenafil Citrate	62	10.1	10.1
Pitavastatin Calcium	5	9.6	9.6
Ranolazine	5	9.4	9.4
Eszopiclone	12	9.3	9.3
Brinzolamide	4	9.1	9.1
Miconazole Nitrate	4	9.0	9.0
Ticagrelor	14	8.7	8.7
Liraglutide	21	8.5	8.5
Acetaminophen, Aspirin, And Caffeine	9	8.4	8.4
Fluticasone Propionate And Salmeterol	17	8.1	8.1
Hydrocodone Bitartrate And Acetaminophen	22	7.8	7.8
Darbepoetin Alfa	21	7.8	7.8
Travoprost	3	6.8	6.8
Exenatide	16	6.0	6.0
Umeclidinium Bromide And Vilanterol Trifenatate	5	5.9	5.9
Patiromer	3	4.3	4.3
Tapentadol Hydrochloride	5	2.9	2.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.