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Drug

Diphenoxylate Hydrochloride And Atropine Sulfate

1,158 flagged reaction(s) · 69,746 total co-reports · max PRR 519.6
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Vaginal Flatulence 77 519.6 522.6 signal
2 Presbyacusis 60 368.8 370.5 signal
3 Gastrointestinal Stoma Output Abnormal 16 192.8 193.0 signal
4 Pleural Thickening 56 137.8 138.4 signal
5 Pleural Fibrosis 70 112.2 112.8 signal
6 Blood Magnesium Increased 57 103.7 104.1 signal
7 Gastrointestinal Stoma Output Increased 26 91.6 91.8 signal
8 Female Genital Tract Fistula 88 82.9 83.5 signal
9 Gastroenteritis Radiation 15 73.2 73.3 signal
10 Bone Cyst 41 70.2 70.4 signal
11 Short-bowel Syndrome 23 56.3 56.4 signal
12 Chronic Sinusitis 124 52.7 53.2 signal
13 Stoma Complication 33 51.4 51.6 signal
14 Radiculopathy 83 50.0 50.3 signal
15 Proctitis 88 49.9 50.2 signal
16 Osteosclerosis 49 49.3 49.5 signal
17 Bulimia Nervosa 11 39.3 39.3 signal
18 Pouchitis 21 38.4 38.5 signal
19 Faecal Volume Decreased 11 35.8 35.9 signal
20 Gastrointestinal Stoma Complication 33 33.2 33.3 signal
21 Deafness Neurosensory 64 30.6 30.8 signal
22 Rectal Fissure 12 29.5 29.6 signal
23 Macular Degeneration 217 28.5 29.0 signal
24 Epigastric Discomfort 68 27.1 27.3 signal
25 Perirectal Abscess 13 18.1 18.1 signal
26 Chronic Kidney Disease-mineral And Bone Disorder 12 17.4 17.4 signal
27 Intestinal Dilatation 14 16.4 16.5 signal
28 Culture Urine Positive 14 15.4 15.4 signal
29 Blood Magnesium Decreased 85 15.3 15.4 signal
30 Small Intestinal Obstruction 117 14.8 14.9 signal
31 Therapeutic Reaction Time Decreased 28 14.8 14.8 signal
32 Paraesthesia Oral 134 14.5 14.6 signal
33 Vascular Device Infection 42 14.4 14.5 signal
34 Failure To Thrive 47 14.0 14.0 signal
35 Blood Electrolytes Abnormal 11 13.8 13.8 signal
36 Hyperparathyroidism Secondary 22 13.5 13.5 signal
37 Incisional Hernia 12 13.4 13.4 signal
38 Nephrogenic Anaemia 40 13.3 13.3 signal
39 Frequent Bowel Movements 229 13.2 13.4 signal
40 Rectal Abscess 14 12.9 12.9 signal
41 Vaginal Discharge 82 12.7 12.7 signal
42 Aortic Arteriosclerosis 21 12.6 12.6 signal
43 Intestinal Mass 11 12.6 12.6 signal
44 Gastrointestinal Wall Thickening 12 12.5 12.5 signal
45 Radiotherapy 15 12.1 12.2 signal
46 Cancer Pain 20 12.1 12.1 signal
47 Oral Candidiasis 101 12.0 12.1 signal
48 Obstruction 31 12.0 12.1 signal
49 Abdominal Adhesions 24 11.7 11.7 signal
50 Osteolysis 15 11.3 11.3 signal
51 Adhesion 11 11.2 11.2 signal
52 Mitral Valve Prolapse 12 11.2 11.2 signal
53 Crohn's Disease 49 10.9 11.0 signal
54 Intestinal Stenosis 29 10.7 10.7 signal
55 Osteopenia 104 10.6 10.6 signal
56 Cyst 84 10.5 10.5 signal
57 Pancreatic Carcinoma Metastatic 19 10.3 10.3 signal
58 Oral Intake Reduced 16 10.1 10.1 signal
59 Colitis 245 10.1 10.2 signal
60 Infusion Site Discharge 11 10.0 10.0 signal
61 Cervical Spinal Stenosis 11 9.8 9.9 signal
62 Proctalgia 40 9.6 9.7 signal
63 Hypovolaemia 36 9.5 9.6 signal
64 Atelectasis 59 9.4 9.5 signal
65 Large Intestinal Stenosis 12 9.4 9.4 signal
66 Malnutrition 67 9.3 9.4 signal
67 Exostosis 55 9.3 9.4 signal
68 Metabolic Encephalopathy 18 9.3 9.3 signal
69 Diverticulum Intestinal 26 9.2 9.3 signal
70 Abnormal Faeces 48 9.1 9.1 signal
71 Lactose Intolerance 15 9.0 9.0 signal
72 Cholangitis Sclerosing 12 9.0 9.0 signal
73 Essential Hypertension 15 9.0 9.0 signal
74 Dehydration 767 8.9 9.4 signal
75 Device Infusion Issue 14 8.8 8.9 signal
76 Enteritis 36 8.8 8.8 signal
77 Abdominal Abscess 25 8.8 8.8 signal
78 Abdominal Hernia 25 8.5 8.5 signal
79 Faeces Hard 21 8.4 8.4 signal
80 Weight Fluctuation 55 8.2 8.2 signal
81 Sprue-like Enteropathy 26 8.1 8.1 signal
82 Blood Potassium Increased 85 8.1 8.1 signal
83 Fistula 59 8.1 8.1 signal
84 Clostridium Difficile Colitis 55 8.0 8.0 signal
85 Oesophageal Ulcer 20 8.0 8.0 signal
86 Clostridium Difficile Infection 112 8.0 8.1 signal
87 Ileostomy 13 8.0 8.0 signal
88 Abscess Intestinal 11 7.9 7.9 signal
89 Ingrowing Nail 12 7.9 7.9 signal
90 Procedural Pain 140 7.8 7.9 signal
91 Anal Fissure 27 7.8 7.8 signal
92 Electrolyte Imbalance 58 7.8 7.8 signal
93 Gastrointestinal Obstruction 12 7.8 7.8 signal
94 Bone Lesion 18 7.7 7.7 signal
95 Spinal Osteoarthritis 44 7.7 7.7 signal
96 Blood Potassium Decreased 148 7.6 7.7 signal
97 Blood Potassium Abnormal 13 7.6 7.6 signal
98 Thrombophlebitis Superficial 15 7.5 7.5 signal
99 Rectal Cancer 15 7.5 7.5 signal
100 Vitamin B12 Decreased 14 7.5 7.5 signal
101 Hiatus Hernia 62 7.4 7.4 signal
102 Lumbar Spinal Stenosis 14 7.4 7.4 signal
103 Azotaemia 19 7.3 7.3 signal
104 Anal Incontinence 42 7.3 7.3 signal
105 Purulent Discharge 20 7.2 7.2 signal
106 Blood Culture Positive 14 7.1 7.1 signal
107 Defaecation Urgency 32 7.1 7.1 signal
108 Rectal Haemorrhage 197 7.1 7.2 signal
109 Oesophageal Candidiasis 18 7.0 7.0 signal
110 Protein Total Decreased 17 7.0 7.0 signal
111 Metastases To Spine 15 6.9 6.9 signal
112 Mucous Stools 22 6.9 6.9 signal
113 Deformity 41 6.8 6.8 signal
114 Abdominal Infection 11 6.7 6.7 signal
115 Faecal Incontinence 21 6.7 6.7 signal
116 Appetite Disorder 28 6.6 6.7 signal
117 Intestinal Obstruction 161 6.6 6.7 signal
118 Performance Status Decreased 20 6.6 6.6 signal
119 Iron Deficiency 19 6.6 6.6 signal
120 Excoriation 11 6.6 6.6 signal
121 Diarrhoea 2,730 6.6 8.0 signal
122 Duodenitis 13 6.6 6.6 signal
123 Colitis Ulcerative 189 6.5 6.6 signal
124 Haemorrhoids 82 6.5 6.5 signal
125 Blood Iron Decreased 49 6.4 6.4 signal
126 Clostridial Infection 14 6.3 6.3 signal
127 Large Intestinal Ulcer 11 6.3 6.3 signal
128 Ileus 50 6.3 6.3 signal
129 Fluid Intake Reduced 20 6.3 6.3 signal
130 Colitis Microscopic 19 6.3 6.3 signal
131 Lung Infiltration 36 6.2 6.3 signal
132 Compression Fracture 21 6.2 6.2 signal
133 Loose Tooth 13 6.2 6.2 signal
134 Infusion Site Haemorrhage 13 6.2 6.2 signal
135 Anal Fistula 21 6.1 6.1 signal
136 Hepatic Lesion 17 6.1 6.1 signal
137 Irritable Bowel Syndrome 84 6.1 6.1 signal
138 Wound Dehiscence 13 5.9 5.9 signal
139 Squamous Cell Carcinoma Of Skin 23 5.9 5.9 signal
140 Skin Lesion 104 5.9 5.9 signal
141 Emphysema 38 5.8 5.8 signal
142 Diverticulum 27 5.8 5.8 signal
143 Skin Papilloma 15 5.8 5.8 signal
144 Hypokalaemia 171 5.8 5.8 signal
145 Lung Neoplasm 16 5.7 5.8 signal
146 Cardiomegaly 46 5.7 5.7 signal
147 Seasonal Allergy 52 5.7 5.7 signal
148 Decubitus Ulcer 30 5.7 5.7 signal
149 Hypomagnesaemia 51 5.7 5.7 signal
150 Hospice Care 36 5.6 5.7 signal
151 Mental Status Changes 101 5.6 5.6 signal
152 Oesophageal Disorder 14 5.6 5.6 signal
153 Multiple Myeloma 17 5.5 5.6 signal
154 Flatulence 203 5.5 5.6 signal
155 Rebound Acid Hypersecretion 11 5.5 5.5 signal
156 Oesophageal Pain 14 5.5 5.5 signal
157 Scoliosis 22 5.5 5.5 signal
158 Tricuspid Valve Incompetence 28 5.5 5.5 signal
159 Haematochezia 193 5.4 5.5 signal
160 Hair Colour Changes 44 5.4 5.4 signal
161 End Stage Renal Disease 64 5.4 5.4 signal
162 Gastrointestinal Infection 31 5.4 5.4 signal
163 Renal Failure Chronic 27 5.3 5.4 signal
164 Blood Calcium Decreased 39 5.3 5.3 signal
165 Gastrointestinal Sounds Abnormal 17 5.3 5.3 signal
166 Large Intestine Perforation 24 5.3 5.3 signal
167 Paranasal Sinus Discomfort 13 5.3 5.3 signal
168 Carotid Artery Stenosis 12 5.3 5.3 signal
169 Yellow Skin 16 5.3 5.3 signal
170 Bacteraemia 40 5.2 5.3 signal
171 Vitamin D Deficiency 33 5.2 5.2 signal
172 Tooth Abscess 34 5.1 5.1 signal
173 Abscess 53 5.1 5.1 signal
174 Osteoarthritis 141 5.1 5.2 signal
175 Cachexia 17 5.1 5.1 signal
176 Upper-airway Cough Syndrome 27 5.1 5.1 signal
177 Blood Albumin Decreased 26 5.1 5.1 signal
178 Facial Bones Fracture 12 5.1 5.1 signal
179 Bundle Branch Block Left 14 5.1 5.1 signal
180 Malabsorption 17 5.1 5.1 signal
181 Plantar Fasciitis 11 5.0 5.0 signal
182 Dental Caries 36 5.0 5.0 signal
183 Supraventricular Extrasystoles 11 5.0 5.0 signal
184 Cerebral Atrophy 13 5.0 5.0 signal
185 Gastrointestinal Inflammation 25 5.0 5.0 signal
186 Colectomy 18 5.0 5.0 signal
187 Haematocrit Decreased 64 4.9 5.0 signal
188 Abdominal Pain 744 4.9 5.2 signal
189 Klebsiella Infection 16 4.9 4.9 signal
190 Large Intestine Polyp 22 4.9 4.9 signal
191 Weight Decreased 885 4.9 5.2 signal
192 Pathological Fracture 16 4.9 4.9 signal
193 Gingival Pain 25 4.8 4.9 signal
194 Hypoalbuminaemia 24 4.8 4.9 signal
195 Red Cell Distribution Width Increased 13 4.8 4.8 signal
196 Peripheral Vascular Disorder 16 4.8 4.8 signal
197 Prostatomegaly 12 4.7 4.7 signal
198 Polyp 20 4.7 4.7 signal
199 Odynophagia 18 4.7 4.7 signal
200 Faeces Discoloured 66 4.7 4.7 signal
201 Increased Tendency To Bruise 28 4.7 4.7 signal
202 Musculoskeletal Chest Pain 47 4.7 4.7 signal
203 Palmar-plantar Erythrodysaesthesia Syndrome 70 4.6 4.6 signal
204 Diarrhoea Haemorrhagic 28 4.6 4.6 signal
205 Umbilical Hernia 14 4.6 4.6 signal
206 Enterocolitis 17 4.6 4.6 signal
207 Metastases To Liver 52 4.6 4.6 signal
208 Non-small Cell Lung Cancer 14 4.6 4.6 signal
209 Abnormal Loss Of Weight 20 4.6 4.6 signal
210 Hyperlipidaemia 35 4.5 4.5 signal
211 Hypervolaemia 14 4.5 4.5 signal
212 Onychoclasis 20 4.5 4.5 signal
213 Systemic Inflammatory Response Syndrome 11 4.5 4.5 signal
214 Pulmonary Mass 43 4.5 4.5 signal
215 Thyroid Function Test Abnormal 12 4.4 4.4 signal
216 Eating Disorder 61 4.4 4.4 signal
217 Iron Deficiency Anaemia 26 4.4 4.4 signal
218 Dermatitis Acneiform 17 4.3 4.3 signal
219 Blood Creatinine Increased 183 4.3 4.4 signal
220 Skin Abrasion 13 4.3 4.3 signal
221 Decreased Appetite 643 4.3 4.4 signal
222 Staphylococcal Bacteraemia 12 4.3 4.3 signal
223 Renal Cyst 22 4.3 4.3 signal
224 Gastroenteritis Viral 50 4.3 4.3 signal
225 Oral Pain 62 4.3 4.3 signal
226 Intestinal Perforation 31 4.3 4.3 signal
227 Bowel Movement Irregularity 21 4.3 4.3 signal
228 Onychomycosis 12 4.2 4.2 signal
229 Splenomegaly 32 4.2 4.2 signal
230 Full Blood Count Decreased 55 4.2 4.2 signal
231 Hyperkeratosis 15 4.2 4.2 signal
232 Benign Prostatic Hyperplasia 14 4.2 4.2 signal
233 Blood Creatine Increased 12 4.2 4.2 signal
234 Dyspepsia 264 4.2 4.2 signal
235 Intervertebral Disc Degeneration 25 4.1 4.1 signal
236 Ovarian Cyst 27 4.1 4.1 signal
237 Hypophagia 68 4.1 4.2 signal
238 Hydronephrosis 20 4.1 4.1 signal
239 Multiple Allergies 21 4.1 4.1 signal
240 Renal Tubular Necrosis 26 4.1 4.1 signal
241 Gastrointestinal Motility Disorder 14 4.1 4.1 signal
242 Ligament Sprain 26 4.1 4.1 signal
243 Hepatic Steatosis 49 4.1 4.1 signal
244 Lipase Increased 20 4.0 4.0 signal
245 Inguinal Hernia 16 4.0 4.0 signal
246 Intestinal Resection 14 4.0 4.0 signal
247 Abdominal Tenderness 13 4.0 4.0 signal
248 Poor Venous Access 27 4.0 4.0 signal
249 Colon Cancer 39 4.0 4.0 signal
250 Blood Sodium Decreased 49 4.0 4.0 signal
251 Muscle Fatigue 11 4.0 4.0 signal
252 Device Related Infection 40 4.0 4.0 signal
253 Escherichia Urinary Tract Infection 11 4.0 4.0 signal
254 Infusion Site Pain 33 4.0 4.0 signal
255 Rales 15 4.0 4.0 signal
256 Wound Infection 28 4.0 4.0 signal
257 Hiccups 21 4.0 4.0 signal
258 Mitral Valve Incompetence 29 4.0 4.0 signal
259 Gastrointestinal Pain 28 3.9 3.9 signal
260 Gastritis 67 3.9 3.9 signal
261 Sinus Tachycardia 36 3.9 3.9 signal
262 Gastroenteritis 37 3.9 3.9 signal
263 Cellulitis 128 3.9 3.9 signal
264 Red Blood Cell Count Decreased 72 3.9 3.9 signal
265 Nephrolithiasis 115 3.9 3.9 signal
266 Ulcer 40 3.9 3.9 signal
267 Renal Failure Acute 108 3.9 3.9 signal
268 Spinal Column Stenosis 12 3.9 3.9 signal
269 Varicose Vein 13 3.9 3.9 signal
270 Spinal Compression Fracture 21 3.9 3.9 signal
271 Infusion Related Reaction 165 3.9 3.9 signal
272 Atrial Flutter 20 3.8 3.9 signal
273 Gastrooesophageal Reflux Disease 200 3.8 3.9 signal
274 Blood Alkaline Phosphatase Increased 62 3.8 3.9 signal
275 Rhinitis Allergic 11 3.8 3.8 signal
276 Stomatitis 149 3.8 3.8 signal
277 Hair Growth Abnormal 17 3.8 3.8 signal
278 Uterine Leiomyoma 18 3.8 3.8 signal
279 Vitamin D Decreased 21 3.8 3.8 signal
280 Tooth Fracture 27 3.8 3.8 signal
281 Arthropod Bite 18 3.8 3.8 signal
282 Escherichia Infection 20 3.8 3.8 signal
283 Metastases To Bone 40 3.8 3.8 signal
284 Anaemia 466 3.8 3.9 signal
285 Cholelithiasis 80 3.8 3.8 signal
286 Sinus Congestion 33 3.8 3.8 signal
287 Cardiac Valve Disease 14 3.8 3.8 signal
288 Hypoxia 85 3.7 3.8 signal
289 Insurance Issue 36 3.7 3.7 signal
290 Arteriosclerosis Coronary Artery 16 3.7 3.7 signal
291 Immunosuppression 21 3.7 3.7 signal
292 Sepsis 270 3.7 3.8 signal
293 Gingivitis 13 3.7 3.7 signal
294 Hair Disorder 20 3.7 3.7 signal
295 Candida Infection 40 3.7 3.7 signal
296 Nocturia 29 3.7 3.7 signal
297 Faecaloma 13 3.7 3.7 signal
298 Localised Oedema 11 3.7 3.7 signal
299 Laboratory Test Abnormal 70 3.7 3.7 signal
300 Rosacea 11 3.7 3.7 signal
301 Blood Disorder 19 3.7 3.7 signal
302 Plasma Cell Myeloma 92 3.6 3.6 signal
303 Urinary Tract Infection 400 3.6 3.7 signal
304 Prostatic Disorder 13 3.6 3.6 signal
305 Disease Progression 277 3.6 3.7 signal
306 Abdominal Distension 244 3.6 3.7 signal
307 Oral Mucosal Blistering 15 3.6 3.6 signal
308 Gastrointestinal Disorder 207 3.6 3.7 signal
309 Metastases To Lung 27 3.6 3.6 signal
310 Rib Fracture 48 3.6 3.6 signal
311 Constipation 502 3.6 3.7 signal
312 Oral Disorder 17 3.6 3.6 signal
313 Nail Disorder 20 3.5 3.6 signal
314 Sleep Apnoea Syndrome 44 3.5 3.6 signal
315 Oesophagitis 25 3.5 3.5 signal
316 Staphylococcal Infection 75 3.5 3.5 signal
317 Bacterial Infection 42 3.5 3.5 signal
318 Skin Ulcer 58 3.5 3.5 signal
319 Ascites 66 3.5 3.5 signal
320 Haemorrhoidal Haemorrhage 11 3.4 3.5 signal
321 Anal Abscess 12 3.4 3.4 signal
322 Hepatomegaly 22 3.4 3.4 signal
323 Muscle Atrophy 28 3.4 3.4 signal
324 Mucosal Inflammation 58 3.4 3.4 signal
325 Madarosis 26 3.4 3.4 signal
326 Pre-existing Condition Improved 14 3.4 3.4 signal
327 Faeces Soft 16 3.4 3.4 signal
328 Foot Fracture 42 3.4 3.4 signal
329 Kidney Infection 43 3.4 3.4 signal
330 Platelet Count Decreased 232 3.4 3.4 signal
331 Hypophosphataemia 16 3.4 3.4 signal
332 Basal Cell Carcinoma 34 3.4 3.4 signal
333 Rotator Cuff Syndrome 28 3.3 3.4 signal
334 Infusion Site Erythema 18 3.3 3.4 signal
335 Therapeutic Product Effect Incomplete 153 3.3 3.4 signal
336 Lung Infection 34 3.3 3.3 signal
337 Incoherent 14 3.3 3.3 signal
338 Hair Texture Abnormal 29 3.3 3.3 signal
339 Local Swelling 38 3.3 3.3 signal
340 Haemoglobin Decreased 221 3.3 3.3 signal
341 Tooth Disorder 48 3.3 3.3 signal
342 Blood Count Abnormal 33 3.3 3.3 signal
343 Renal Failure 286 3.3 3.3 signal
344 Hyperbilirubinaemia 22 3.3 3.3 signal
345 Duodenal Ulcer 15 3.3 3.3 signal
346 Right Ventricular Failure 15 3.3 3.3 signal
347 Cholecystitis Acute 12 3.3 3.3 signal
348 Cerebral Ischaemia 11 3.3 3.3 signal
349 Pain In Jaw 60 3.3 3.3 signal
350 Tenderness 22 3.2 3.3 signal
351 White Blood Cell Count Decreased 228 3.2 3.3 signal
352 Blood Lactic Acid Increased 11 3.2 3.2 signal
353 Breast Mass 14 3.2 3.2 signal
354 Post Procedural Complication 40 3.2 3.2 signal
355 Postoperative Wound Infection 14 3.2 3.2 signal
356 Thyroid Disorder 32 3.2 3.2 signal
357 Bursitis 25 3.2 3.2 signal
358 Cardiac Murmur 18 3.2 3.2 signal
359 Pleural Effusion 126 3.2 3.2 signal
360 Limb Injury 56 3.2 3.2 signal
361 Food Poisoning 11 3.2 3.2 signal
362 Cystitis 66 3.2 3.2 signal
363 Pulmonary Hypertension 43 3.2 3.2 signal
364 Bronchitis 153 3.2 3.2 signal
365 Anorectal Discomfort 11 3.2 3.2 signal
366 Urine Output Decreased 18 3.2 3.2 signal
367 Nausea 1,620 3.2 3.5 signal
368 Neuropathy Peripheral 194 3.2 3.2 signal
369 Multiple Injuries 13 3.1 3.1 signal
370 Acute Respiratory Failure 39 3.1 3.1 signal
371 Cheilitis 11 3.1 3.1 signal
372 Retching 43 3.1 3.1 signal
373 Economic Problem 31 3.1 3.1 signal
374 Dry Eye 97 3.1 3.1 signal
375 Neoplasm 23 3.1 3.1 signal
376 Chronic Obstructive Pulmonary Disease 104 3.1 3.1 signal
377 Anorexia 26 3.1 3.1 signal
378 Brain Fog 29 3.1 3.1 signal
379 Troponin Increased 15 3.1 3.1 signal
380 Supraventricular Tachycardia 19 3.1 3.1 signal
381 Incontinence 21 3.1 3.1 signal
382 Scar 34 3.1 3.1 signal
383 Bedridden 26 3.1 3.1 signal
384 International Normalised Ratio Increased 57 3.1 3.1 signal
385 Transient Ischaemic Attack 67 3.0 3.1 signal
386 Post Procedural Infection 16 3.0 3.0 signal
387 Skin Infection 22 3.0 3.0 signal
388 Oedema Peripheral 241 3.0 3.1 signal
389 Osteoporosis 81 3.0 3.0 signal
390 Spinal Fracture 39 3.0 3.0 signal
391 Drug Level Decreased 20 3.0 3.0 signal
392 Gallbladder Disorder 35 3.0 3.0 signal
393 Vomiting 916 3.0 3.2 signal
394 Mouth Ulceration 41 3.0 3.0 signal
395 Body Height Decreased 21 3.0 3.0 signal
396 Metastases To Lymph Nodes 13 3.0 3.0 signal
397 Cholecystitis 23 3.0 3.0 signal
398 Flank Pain 18 3.0 3.0 signal
399 Product Distribution Issue 17 3.0 3.0 signal
400 Nodule 25 3.0 3.0 signal
401 Asthenia 716 2.9 3.0 signal
402 Electrocardiogram Abnormal 15 2.9 2.9 signal
403 Dysphonia 111 2.9 2.9 signal
404 Fatigue 1,475 2.9 3.2 signal
405 Chronic Kidney Disease 145 2.9 2.9 signal
406 Gastric Ulcer 36 2.9 2.9 signal
407 Orthostatic Hypotension 33 2.9 2.9 signal
408 Impaired Healing 62 2.9 2.9 signal
409 Laceration 18 2.9 2.9 signal
410 Lymphoedema 13 2.9 2.9 signal
411 Deep Vein Thrombosis 123 2.9 2.9 signal
412 Impaired Gastric Emptying 24 2.9 2.9 signal
413 Joint Injury 40 2.9 2.9 signal
414 Intervertebral Disc Protrusion 41 2.9 2.9 signal
415 Hypersomnia 53 2.9 2.9 signal
416 Bone Disorder 34 2.9 2.9 signal
417 Dermatitis Contact 21 2.9 2.9 signal
418 Fluid Retention 94 2.9 2.9 signal
419 Diverticulitis 51 2.8 2.9 signal
420 Upper Respiratory Tract Infection 85 2.8 2.9 signal
421 Drug Intolerance 177 2.8 2.9 signal
422 Dyspnoea Exertional 69 2.8 2.8 signal
423 Blood Pressure Systolic Increased 36 2.8 2.8 signal
424 Fungal Infection 61 2.8 2.8 signal
425 Fluid Overload 27 2.8 2.8 signal
426 Cardiomyopathy 27 2.8 2.8 signal
427 Dysuria 67 2.8 2.8 signal
428 Adverse Reaction 24 2.8 2.8 signal
429 Concussion 14 2.8 2.8 signal
430 Transfusion 19 2.8 2.8 signal
431 Malignant Neoplasm Progression 184 2.8 2.8 signal
432 Skin Mass 12 2.8 2.8 signal
433 Arteriosclerosis 17 2.8 2.8 signal
434 Respiratory Rate Increased 16 2.8 2.8 signal
435 Oral Discomfort 25 2.8 2.8 signal
436 Blood Pressure Increased 275 2.8 2.8 signal
437 Hypothyroidism 57 2.8 2.8 signal
438 Generalised Oedema 22 2.8 2.8 signal
439 Infusion Site Swelling 11 2.8 2.8 signal
440 Mass 25 2.7 2.8 signal
441 Hypercalcaemia 22 2.7 2.8 signal
442 Hypercholesterolaemia 17 2.7 2.7 signal
443 Pancytopenia 99 2.7 2.8 signal
444 Major Depression 13 2.7 2.7 signal
445 Mouth Haemorrhage 13 2.7 2.7 signal
446 Breast Cancer Metastatic 19 2.7 2.7 signal
447 Sciatica 28 2.7 2.7 signal
448 Sinus Disorder 35 2.7 2.7 signal
449 Respiratory Tract Congestion 28 2.7 2.7 signal
450 Ageusia 44 2.7 2.7 signal
451 Cytopenia 21 2.7 2.7 signal
452 Increased Appetite 33 2.7 2.7 signal
453 Gingival Bleeding 24 2.7 2.7 signal
454 Blood Pressure Diastolic Decreased 13 2.7 2.7 signal
455 Taste Disorder 35 2.7 2.7 signal
456 Frustration Tolerance Decreased 14 2.7 2.7 signal
457 Muscle Strain 15 2.7 2.7 signal
458 Urosepsis 16 2.7 2.7 signal
459 Sinusitis 178 2.7 2.7 signal
460 Cardiac Failure Congestive 140 2.7 2.7 signal
461 Hypoaesthesia Oral 26 2.7 2.7 signal
462 Bone Pain 101 2.7 2.7 signal
463 Renal Impairment 144 2.7 2.7 signal
464 Haemoglobin Abnormal 11 2.6 2.7 signal
465 Osteomyelitis 31 2.6 2.6 signal
466 Body Temperature Decreased 17 2.6 2.6 signal
467 Foot Deformity 19 2.6 2.6 signal
468 Productive Cough 81 2.6 2.6 signal
469 Carpal Tunnel Syndrome 24 2.6 2.6 signal
470 Upper Limb Fracture 34 2.6 2.6 signal
471 Blood Bilirubin Increased 46 2.6 2.6 signal
472 Squamous Cell Carcinoma 16 2.6 2.6 signal
473 Hyperkalaemia 59 2.6 2.6 signal
474 Refusal Of Treatment By Patient 11 2.6 2.6 signal
475 Night Sweats 54 2.6 2.6 signal
476 Embolism 14 2.6 2.6 signal
477 Contusion 161 2.6 2.6 signal
478 Pyrexia 579 2.6 2.6 signal
479 Ejection Fraction Decreased 26 2.6 2.6 signal
480 Wrist Fracture 20 2.6 2.6 signal
481 Tooth Infection 22 2.6 2.6 signal
482 Blood Urea Increased 28 2.6 2.6 signal
483 Hernia 32 2.6 2.6 signal
484 Blood Pressure Fluctuation 40 2.6 2.6 signal
485 Gastrointestinal Haemorrhage 139 2.5 2.6 signal
486 Pneumonia 534 2.5 2.6 signal
487 Hip Fracture 53 2.5 2.6 signal
488 Pulmonary Thrombosis 18 2.5 2.5 signal
489 Tongue Disorder 12 2.5 2.5 signal
490 Furuncle 13 2.5 2.5 signal
491 Arthritis 129 2.5 2.5 signal
492 Colitis Ischaemic 11 2.5 2.5 signal
493 Coeliac Disease 16 2.5 2.5 signal
494 Pancreatitis 86 2.5 2.5 signal
495 Abdominal Pain Lower 41 2.5 2.5 signal
496 Infection 233 2.5 2.5 signal
497 Rhinitis 13 2.5 2.5 signal
498 Localised Infection 39 2.5 2.5 signal
499 Respiration Abnormal 11 2.5 2.5 signal
500 Renal Disorder 75 2.5 2.5 signal
501 Hypotension 321 2.5 2.5 signal
502 Acute Kidney Injury 244 2.5 2.5 signal
503 Ecchymosis 11 2.5 2.5 signal
504 Thrombosis 129 2.5 2.5 signal
505 Septic Shock 69 2.5 2.5 signal
506 Coronary Artery Occlusion 22 2.5 2.5 signal
507 Dysphagia 151 2.5 2.5 signal
508 Ear Pain 31 2.5 2.5 signal
509 Restless Legs Syndrome 29 2.5 2.5 signal
510 Encephalopathy 39 2.5 2.5 signal
511 Joint Effusion 11 2.4 2.5 signal
512 Blood Pressure Decreased 105 2.4 2.5 signal
513 Muscle Spasms 290 2.4 2.5 signal
514 Sleep Disorder 110 2.4 2.4 signal
515 Pharyngitis Streptococcal 17 2.4 2.4 signal
516 Thrombocytopenia 175 2.4 2.4 signal
517 Back Pain 364 2.4 2.5 signal
518 Glossodynia 35 2.4 2.4 signal
519 Osteonecrosis Of Jaw 39 2.4 2.4 signal
520 Dizziness Postural 15 2.4 2.4 signal
521 Metastases To Central Nervous System 20 2.4 2.4 signal
522 Feeding Disorder 31 2.4 2.4 signal
523 Blood Glucose Fluctuation 17 2.4 2.4 signal
524 Coronary Artery Disease 47 2.4 2.4 signal
525 Heart Rate Irregular 35 2.4 2.4 signal
526 Ventricular Extrasystoles 16 2.4 2.4 signal
527 Pseudomonas Infection 13 2.4 2.4 signal
528 Blister 86 2.4 2.4 signal
529 Epistaxis 115 2.4 2.4 signal
530 Blood Urine Present 29 2.3 2.3 signal
531 Arterial Occlusive Disease 12 2.3 2.3 signal
532 Cataract 90 2.3 2.3 signal
533 Dysarthria 57 2.3 2.3 signal
534 Abdominal Pain Upper 311 2.3 2.4 signal
535 Wound 42 2.3 2.3 signal
536 Atrial Fibrillation 147 2.3 2.3 signal
537 Adrenal Insufficiency 18 2.3 2.3 signal
538 Injection Site Irritation 19 2.3 2.3 signal
539 Respiratory Failure 109 2.3 2.3 signal
540 Leukocytosis 27 2.3 2.3 signal
541 Hepatic Enzyme Increased 101 2.3 2.3 signal
542 Proteinuria 28 2.3 2.3 signal
543 Metabolic Acidosis 47 2.3 2.3 signal
544 Hypocalcaemia 28 2.3 2.3 signal
545 Myocardial Ischaemia 17 2.3 2.3 signal
546 Pneumonitis 40 2.3 2.3 signal
547 Sluggishness 15 2.3 2.3 signal
548 Aspiration 16 2.3 2.3 signal
549 Hyponatraemia 83 2.3 2.3 signal
550 Pulmonary Oedema 66 2.3 2.3 signal
551 Liver Function Test Abnormal 43 2.3 2.3 signal
552 Head Injury 46 2.2 2.2 signal
553 Chills 171 2.2 2.3 signal
554 Tendon Rupture 18 2.2 2.2 signal
555 Liver Function Test Increased 31 2.2 2.2 signal
556 Syncope 145 2.2 2.2 signal
557 Jaundice 39 2.2 2.2 signal
558 Mobility Decreased 103 2.2 2.2 signal
559 Toothache 26 2.2 2.2 signal
560 Neck Pain 80 2.2 2.2 signal
561 Fall 475 2.2 2.2 signal
562 Pulmonary Embolism 136 2.2 2.2 signal
563 Joint Dislocation 15 2.2 2.2 signal
564 Neoplasm Progression 50 2.2 2.2 signal
565 Joint Range Of Motion Decreased 19 2.2 2.2 signal
566 Eye Haemorrhage 19 2.2 2.2 signal
567 Abdominal Discomfort 237 2.2 2.2 signal
568 Haematemesis 36 2.2 2.2 signal
569 Brain Neoplasm 13 2.2 2.2 signal
570 Throat Tightness 38 2.2 2.2 signal
571 Glomerular Filtration Rate Decreased 17 2.2 2.2 signal
572 Internal Haemorrhage 16 2.2 2.2 signal
573 Myasthenia Gravis 11 2.2 2.2 signal
574 Ear Infection 37 2.1 2.2 signal
575 Febrile Neutropenia 92 2.1 2.1 signal
576 Skin Laceration 15 2.1 2.1 signal
577 Pneumothorax 22 2.1 2.1 signal
578 Influenza 155 2.1 2.1 signal
579 Oedema 75 2.1 2.1 signal
580 Coagulopathy 23 2.1 2.1 signal
581 Skin Disorder 46 2.1 2.1 signal
582 Peripheral Swelling 212 2.1 2.1 signal
583 Arthropathy 77 2.1 2.1 signal
584 Peripheral Coldness 19 2.1 2.1 signal
585 Sputum Discoloured 13 2.1 2.1 signal
586 Haematuria 47 2.1 2.1 signal
587 Spinal Disorder 13 2.1 2.1 signal
588 Blood Calcium Increased 12 2.1 2.1 signal
589 Injection Site Haematoma 20 2.1 2.1 signal
590 Stress 98 2.1 2.1 signal
591 Aphonia 19 2.1 2.1 signal
592 Malaise 594 2.1 2.1 signal
593 Oropharyngeal Pain 125 2.1 2.1 signal
594 Hypertension 286 2.1 2.1 signal
595 Chest Pain 250 2.1 2.1 signal
596 Thirst 24 2.1 2.1 signal
597 Activities Of Daily Living Impaired 27 2.1 2.1 signal
598 Obstructive Airways Disorder 15 2.1 2.1 signal
599 Dysgeusia 100 2.1 2.1 signal
600 Gout 24 2.1 2.1 signal
601 Dialysis 19 2.1 2.1 signal
602 Hyperaesthesia 11 2.0 2.0 signal
603 Inflammatory Bowel Disease 13 2.0 2.0 signal
604 Amnesia 86 2.0 2.0 signal
605 Blood Pressure Abnormal 26 2.0 2.0 signal
606 Syringe Issue 23 2.0 2.0 signal
607 Weight Increased 292 2.0 2.0 signal
608 Pericardial Effusion 30 2.0 2.0 signal
609 Herpes Zoster 75 2.0 2.0 signal
610 Drug Effect Incomplete 48 2.0 2.0 signal
611 Platelet Count Increased 17 2.0 2.0 signal
612 Cough 364 2.0 2.0 signal
613 Aspartate Aminotransferase Increased 69 2.0 2.0 signal
614 Skin Cancer 28 2.0 2.0 signal
615 Hyperglycaemia 47 2.0 2.0 no signal
616 Ankle Fracture 20 2.0 2.0 no signal
617 Musculoskeletal Pain 68 2.0 2.0 no signal
618 Lethargy 74 2.0 2.0 no signal
619 Urinary Incontinence 38 2.0 2.0 no signal
620 Hypoaesthesia 192 2.0 2.0 no signal
621 Nephropathy 12 2.0 2.0 no signal
622 Temperature Intolerance 13 2.0 2.0 no signal
623 White Blood Cell Count Increased 49 2.0 2.0 no signal
624 Confusional State 206 2.0 2.0 no signal
625 Pain 782 2.0 2.0 no signal
626 Lymphadenopathy 45 2.0 2.0 no signal
627 Quality Of Life Decreased 17 1.9 2.0 no signal
628 Pain In Extremity 373 1.9 2.0 no signal
629 Viral Infection 42 1.9 1.9 no signal
630 Arthralgia 523 1.9 2.0 no signal
631 Muscle Twitching 29 1.9 1.9 no signal
632 Eye Infection 14 1.9 1.9 no signal
633 Rash Pruritic 67 1.9 1.9 no signal
634 Nasopharyngitis 229 1.9 1.9 no signal
635 Chromaturia 28 1.9 1.9 no signal
636 Sinus Bradycardia 12 1.9 1.9 no signal
637 Joint Swelling 149 1.9 1.9 no signal
638 Facial Pain 11 1.9 1.9 no signal
639 Respiratory Tract Infection 32 1.9 1.9 no signal
640 Vitreous Floaters 12 1.9 1.9 no signal
641 Product Dose Omission In Error 33 1.9 1.9 no signal
642 Tubulointerstitial Nephritis 23 1.9 1.9 no signal
643 Diabetes Mellitus 94 1.9 1.9 no signal
644 Depression 280 1.9 1.9 no signal
645 Body Temperature Increased 25 1.9 1.9 no signal
646 Musculoskeletal Discomfort 21 1.9 1.9 no signal
647 Sudden Death 13 1.9 1.9 no signal
648 Gastric Haemorrhage 14 1.9 1.9 no signal
649 Ventricular Tachycardia 20 1.9 1.9 no signal
650 Back Injury 13 1.8 1.9 no signal
651 Swelling 112 1.8 1.9 no signal
652 Laryngitis 13 1.8 1.8 no signal
653 Neuralgia 29 1.8 1.8 no signal
654 Dyspnoea 675 1.8 1.9 no signal
655 Contraindicated Product Administered 36 1.8 1.8 no signal
656 Tachycardia 106 1.8 1.8 no signal
657 Heart Rate Increased 118 1.8 1.8 no signal
658 Blood Thyroid Stimulating Hormone Increased 11 1.8 1.8 no signal
659 Migraine 113 1.8 1.8 no signal
660 Eyelid Ptosis 12 1.8 1.8 no signal
661 Neutropenia 159 1.8 1.8 no signal
662 Respiratory Disorder 35 1.8 1.8 no signal
663 Therapy Non-responder 52 1.8 1.8 no signal
664 Skin Fissures 22 1.8 1.8 no signal
665 Limb Discomfort 36 1.8 1.8 no signal
666 Drug Hypersensitivity 225 1.8 1.8 no signal
667 Tendonitis 18 1.8 1.8 no signal
668 Presyncope 28 1.8 1.8 no signal
669 Illness 116 1.8 1.8 no signal
670 Immunodeficiency 17 1.8 1.8 no signal
671 Pulmonary Fibrosis 22 1.8 1.8 no signal
672 Micturition Urgency 13 1.8 1.8 no signal
673 Cholecystectomy 13 1.8 1.8 no signal
674 Balance Disorder 99 1.8 1.8 no signal
675 Glaucoma 22 1.8 1.8 no signal
676 Coordination Abnormal 16 1.8 1.8 no signal
677 Blood Triglycerides Increased 20 1.7 1.7 no signal
678 Hepatic Cirrhosis 21 1.7 1.7 no signal
679 Alanine Aminotransferase Increased 69 1.7 1.7 no signal
680 Muscular Weakness 127 1.7 1.7 no signal
681 Vasculitis 13 1.7 1.7 no signal
682 Haematoma 29 1.7 1.7 no signal
683 Wrong Technique In Drug Usage Process 41 1.7 1.7 no signal
684 Angina Pectoris 32 1.7 1.7 no signal
685 Loss Of Consciousness 142 1.7 1.7 no signal
686 Pollakiuria 46 1.7 1.7 no signal
687 Therapeutic Product Effect Decreased 49 1.7 1.7 no signal
688 Pelvic Pain 20 1.7 1.7 no signal
689 Pulmonary Arterial Hypertension 16 1.7 1.7 no signal
690 Adverse Drug Reaction 98 1.7 1.7 no signal
691 Alopecia 215 1.7 1.7 no signal
692 Pharyngeal Oedema 17 1.7 1.7 no signal
693 Myalgia 185 1.7 1.7 no signal
694 Skin Discolouration 50 1.7 1.7 no signal
695 Nervousness 57 1.7 1.7 no signal
696 Lung Disorder 53 1.7 1.7 no signal
697 Ovarian Cancer 10 1.7 1.7 no signal
698 Eye Discharge 11 1.7 1.7 no signal
699 Swelling Face 70 1.7 1.7 no signal
700 Appendicitis 10 1.7 1.7 no signal
701 Ear Discomfort 11 1.7 1.7 no signal
702 Haemoptysis 30 1.7 1.7 no signal
703 Insomnia 286 1.7 1.7 no signal
704 Headache 671 1.7 1.7 no signal
705 Photophobia 20 1.6 1.7 no signal
706 Rhinorrhoea 69 1.6 1.7 no signal
707 Cardiac Disorder 100 1.6 1.6 no signal
708 Dizziness 530 1.6 1.7 no signal
709 Immune System Disorder 14 1.6 1.6 no signal
710 Impaired Driving Ability 12 1.6 1.6 no signal
711 Tooth Loss 22 1.6 1.6 no signal
712 Urinary Retention 35 1.6 1.6 no signal
713 Skeletal Injury 11 1.6 1.6 no signal
714 No Therapeutic Response 13 1.6 1.6 no signal
715 Autoimmune Disorder 10 1.6 1.6 no signal
716 Pharyngitis 13 1.6 1.6 no signal
717 Pneumonia Aspiration 26 1.6 1.6 no signal
718 Hunger 14 1.6 1.6 no signal
719 Dry Mouth 84 1.6 1.6 no signal
720 Neutrophil Count Decreased 42 1.6 1.6 no signal
721 Convulsion 60 1.6 1.6 no signal
722 Breast Pain 11 1.6 1.6 no signal
723 Joint Stiffness 27 1.6 1.6 no signal
724 Injection Site Bruising 81 1.6 1.6 no signal
725 Hepatic Failure 31 1.6 1.6 no signal
726 Spinal Pain 12 1.6 1.6 no signal
727 Hyperhidrosis 132 1.6 1.6 no signal
728 Influenza Like Illness 84 1.6 1.6 no signal
729 Central Nervous System Lesion 14 1.6 1.6 no signal
730 Dementia 28 1.5 1.5 no signal
731 Rash Macular 35 1.5 1.5 no signal
732 Bladder Disorder 10 1.5 1.5 no signal
733 Neoplasm Malignant 67 1.5 1.5 no signal
734 Haemorrhage 105 1.5 1.6 no signal
735 Musculoskeletal Stiffness 88 1.5 1.5 no signal
736 Anxiety 286 1.5 1.6 no signal
737 Red Blood Cell Sedimentation Rate Increased 11 1.5 1.5 no signal
738 Chest Discomfort 101 1.5 1.5 no signal
739 Flushing 101 1.5 1.5 no signal
740 Dry Throat 10 1.5 1.5 no signal
741 Complication Associated With Device 13 1.5 1.5 no signal
742 Disorientation 39 1.5 1.5 no signal
743 Initial Insomnia 10 1.5 1.5 no signal
744 Road Traffic Accident 41 1.5 1.5 no signal
745 Rash Papular 22 1.5 1.5 no signal
746 Choking 19 1.5 1.5 no signal
747 Type 2 Diabetes Mellitus 33 1.5 1.5 no signal
748 Secretion Discharge 12 1.5 1.5 no signal
749 Rash 421 1.5 1.5 no signal
750 Scab 11 1.5 1.5 no signal
751 Gait Disturbance 186 1.5 1.5 no signal
752 Folliculitis 10 1.5 1.5 no signal
753 Feeling Cold 27 1.5 1.5 no signal
754 Erythema 198 1.5 1.5 no signal
755 Hepatic Encephalopathy 9 1.5 1.5 no signal
756 Feeling Abnormal 231 1.5 1.5 no signal
757 Nasal Congestion 56 1.5 1.5 no signal
758 Blood Glucose Decreased 46 1.5 1.5 no signal
759 Vertigo 58 1.5 1.5 no signal
760 Brain Oedema 12 1.5 1.5 no signal
761 Dry Skin 125 1.5 1.5 no signal
762 Hypoglycaemia 46 1.5 1.5 no signal
763 Gastric Disorder 33 1.5 1.5 no signal
764 Renal Pain 10 1.5 1.5 no signal
765 Eructation 18 1.5 1.5 no signal
766 Blood Cholesterol Increased 44 1.5 1.5 no signal
767 Lower Limb Fracture 18 1.5 1.5 no signal
768 Leukopenia 47 1.5 1.5 no signal
769 Synovitis 17 1.5 1.5 no signal
770 Throat Irritation 42 1.4 1.4 no signal
771 Sneezing 21 1.4 1.4 no signal
772 Prostatic Specific Antigen Increased 13 1.4 1.4 no signal
773 Drug Dose Omission 157 1.4 1.4 no signal
774 Device Occlusion 13 1.4 1.4 no signal
775 Drug Effect Decreased 51 1.4 1.4 no signal
776 Hospitalisation 142 1.4 1.4 no signal
777 Product Use Issue 174 1.4 1.4 no signal
778 Wheezing 55 1.4 1.4 no signal
779 Inappropriate Schedule Of Product Administration 164 1.4 1.4 no signal
780 Knee Operation 9 1.4 1.4 no signal
781 Treatment Failure 76 1.4 1.4 no signal
782 Blood Test Abnormal 13 1.4 1.4 no signal
783 Covid-19 Pneumonia 11 1.4 1.4 no signal
784 Tremor 153 1.4 1.4 no signal
785 Hypersensitivity 170 1.4 1.4 no signal
786 Multi-organ Failure 16 1.4 1.4 no signal
787 Pruritus Generalised 20 1.4 1.4 no signal
788 Memory Impairment 125 1.4 1.4 no signal
789 Somnolence 182 1.4 1.4 no signal
790 Respiratory Distress 25 1.4 1.4 no signal
791 Subdural Haematoma 13 1.4 1.4 no signal
792 Product Use Complaint 14 1.4 1.4 no signal
793 Myocardial Infarction 158 1.4 1.4 no signal
794 Nerve Injury 10 1.4 1.4 no signal
795 Pancreatitis Acute 20 1.4 1.4 no signal
796 Malignant Melanoma 12 1.4 1.4 no signal
797 Product Dose Omission 59 1.4 1.4 no signal
798 Hot Flush 67 1.4 1.4 no signal
799 Injection Site Pruritus 59 1.4 1.4 no signal
800 Tooth Extraction 11 1.4 1.4 no signal
801 Hemiparesis 15 1.4 1.4 no signal
802 Oxygen Saturation Decreased 49 1.4 1.4 no signal
803 Vision Blurred 119 1.3 1.3 no signal
804 Conjunctivitis 16 1.3 1.3 no signal
805 Dermatitis 18 1.3 1.3 no signal
806 Nerve Compression 8 1.3 1.3 no signal
807 Off Label Use 752 1.3 1.4 no signal
808 Petechiae 9 1.3 1.3 no signal
809 Melaena 19 1.3 1.3 no signal
810 Drug Ineffective 1,130 1.3 1.4 no signal
811 Back Disorder 14 1.3 1.3 no signal
812 Inflammation 44 1.3 1.3 no signal
813 Device Failure 13 1.3 1.3 no signal
814 Post Procedural Haemorrhage 10 1.3 1.3 no signal
815 Hip Arthroplasty 13 1.3 1.3 no signal
816 Therapy Interrupted 59 1.3 1.3 no signal
817 Full Blood Count Abnormal 9 1.3 1.3 no signal
818 Dysstasia 25 1.3 1.3 no signal
819 Heart Rate Decreased 30 1.3 1.3 no signal
820 Paraesthesia 134 1.3 1.3 no signal
821 Injury 60 1.3 1.3 no signal
822 Leukaemia 8 1.3 1.3 no signal
823 Diplopia 22 1.3 1.3 no signal
824 Unevaluable Event 64 1.3 1.3 no signal
825 Inappropriate Schedule Of Drug Administration 61 1.3 1.3 no signal
826 Poor Quality Sleep 18 1.3 1.3 no signal
827 Posterior Reversible Encephalopathy Syndrome 8 1.3 1.3 no signal
828 Decreased Activity 9 1.3 1.3 no signal
829 Accident 10 1.3 1.3 no signal
830 Ataxia 10 1.3 1.3 no signal
831 Hypoacusis 36 1.3 1.3 no signal
832 Pharyngeal Swelling 8 1.3 1.3 no signal
833 Liver Disorder 37 1.3 1.3 no signal
834 Injection Site Pain 253 1.3 1.3 no signal
835 Pulmonary Congestion 11 1.3 1.3 no signal
836 Anhedonia 22 1.3 1.3 no signal
837 Cyanosis 13 1.3 1.3 no signal
838 Oral Herpes 16 1.3 1.3 no signal
839 Rheumatoid Arthritis 93 1.3 1.3 no signal
840 Bipolar Disorder 9 1.3 1.3 no signal
841 Systemic Lupus Erythematosus 29 1.3 1.3 no signal
842 Injection Site Nodule 9 1.3 1.3 no signal
843 Injection Site Haemorrhage 65 1.3 1.3 no signal
844 Knee Arthroplasty 17 1.3 1.3 no signal
845 Eye Swelling 30 1.2 1.3 no signal
846 Surgery 47 1.2 1.2 no signal
847 Blood Glucose Abnormal 15 1.2 1.2 no signal
848 Intentional Product Use Issue 71 1.2 1.2 no signal
849 Emotional Disorder 25 1.2 1.2 no signal
850 Needle Issue 23 1.2 1.2 no signal
851 Swollen Tongue 25 1.2 1.2 no signal
852 Head Discomfort 14 1.2 1.2 no signal
853 Covid-19 140 1.2 1.2 no signal
854 Diabetes Mellitus Inadequate Control 14 1.2 1.2 no signal
855 Dyskinesia 32 1.2 1.2 no signal
856 Eye Pruritus 26 1.2 1.2 no signal
857 Burning Sensation 55 1.2 1.2 no signal
858 Subarachnoid Haemorrhage 8 1.2 1.2 no signal
859 Anaphylactic Reaction 43 1.2 1.2 no signal
860 Fibromyalgia 19 1.2 1.2 no signal
861 Blindness Unilateral 11 1.2 1.2 no signal
862 Mental Disorder 34 1.2 1.2 no signal
863 Neutrophil Count Increased 8 1.2 1.2 no signal
864 Palpitations 91 1.2 1.2 no signal
865 Acute Myocardial Infarction 23 1.2 1.2 no signal
866 Discomfort 47 1.2 1.2 no signal
867 Lung Neoplasm Malignant 32 1.2 1.2 no signal
868 Cardiac Arrest 64 1.2 1.2 no signal
869 Bradycardia 41 1.2 1.2 no signal
870 Pallor 21 1.2 1.2 no signal
871 Bronchospasm 11 1.2 1.2 no signal
872 Paralysis 11 1.2 1.2 no signal
873 Cerebrovascular Accident 130 1.2 1.2 no signal
874 Depressed Mood 40 1.2 1.2 no signal
875 Injection Site Mass 28 1.2 1.2 no signal
876 Aphasia 23 1.2 1.2 no signal
877 Skin Exfoliation 63 1.2 1.2 no signal
878 Abasia 19 1.2 1.2 no signal
879 Product Dose Omission Issue 215 1.2 1.2 no signal
880 Cerebral Haemorrhage 27 1.2 1.2 no signal
881 Obesity 12 1.2 1.2 no signal
882 Device Use Issue 13 1.2 1.2 no signal
883 Personality Change 7 1.2 1.2 no signal
884 Speech Disorder 39 1.1 1.1 no signal
885 Therapy Cessation 38 1.1 1.1 no signal
886 Blood Glucose Increased 140 1.1 1.1 no signal
887 Panic Attack 27 1.1 1.1 no signal
888 Depressed Level Of Consciousness 29 1.1 1.1 no signal
889 Hallucination 55 1.1 1.1 no signal
890 Feeling Jittery 14 1.1 1.1 no signal
891 Visual Impairment 90 1.1 1.1 no signal
892 Musculoskeletal Disorder 14 1.1 1.1 no signal
893 Injection Site Erythema 90 1.1 1.1 no signal
894 Therapy Change 7 1.1 1.1 no signal
895 Injection Site Discolouration 9 1.1 1.1 no signal
896 Peritonitis 15 1.1 1.1 no signal
897 Drug Toxicity 10 1.1 1.1 no signal
898 Rash Generalised 19 1.1 1.1 no signal
899 Ventricular Fibrillation 8 1.1 1.1 no signal
900 Treatment Noncompliance 39 1.1 1.1 no signal
901 Incorrect Dose Administered 161 1.1 1.1 no signal
902 Irritability 43 1.1 1.1 no signal
903 Product Availability Issue 16 1.1 1.1 no signal
904 Upper Gastrointestinal Haemorrhage 12 1.1 1.1 no signal
905 Femur Fracture 22 1.1 1.1 no signal
906 Disability 14 1.1 1.1 no signal
907 Acute Myeloid Leukaemia 11 1.1 1.1 no signal
908 Impaired Quality Of Life 10 1.1 1.1 no signal
909 Gait Inability 23 1.1 1.1 no signal
910 Arrhythmia 33 1.1 1.1 no signal
911 Motor Dysfunction 7 1.1 1.1 no signal
912 Condition Aggravated 208 1.1 1.1 no signal
913 Therapeutic Response Unexpected 31 1.1 1.1 no signal
914 Hypokinesia 10 1.1 1.1 no signal
915 Device Issue 60 1.1 1.1 no signal
916 Ocular Hyperaemia 32 1.1 1.1 no signal
917 Eyelid Oedema 8 1.1 1.1 no signal
918 Cold Sweat 12 1.0 1.0 no signal
919 Incorrect Product Storage 9 1.0 1.0 no signal
920 Ill-defined Disorder 41 1.0 1.0 no signal
921 Sars-cov-2 Test Positive 9 1.0 1.0 no signal
922 Product Taste Abnormal 9 1.0 1.0 no signal
923 Delirium 23 1.0 1.0 no signal
924 Drug Level Increased 11 1.0 1.0 no signal
925 Therapy Partial Responder 10 1.0 1.0 no signal
926 Osteonecrosis 22 1.0 1.0 no signal
927 Multiple Fractures 11 1.0 1.0 no signal
928 General Physical Health Deterioration 76 1.0 1.0 no signal
929 Unresponsive To Stimuli 17 1.0 1.0 no signal
930 Asthma 74 1.0 1.0 no signal
931 Visual Acuity Reduced 22 1.0 1.0 no signal
932 Pancreatic Carcinoma 19 1.0 1.0 no signal
933 Retinal Detachment 6 1.0 1.0 no signal
934 Loss Of Personal Independence In Daily Activities 31 1.0 1.0 no signal
935 Death 560 1.0 1.0 no signal
936 Product Packaging Issue 6 1.0 1.0 no signal
937 Multiple Organ Dysfunction Syndrome 18 1.0 1.0 no signal
938 Acne 49 1.0 1.0 no signal
939 Product Packaging Quantity Issue 7 1.0 1.0 no signal
940 Eye Disorder 21 1.0 1.0 no signal
941 Nervous System Disorder 20 1.0 1.0 no signal
942 Disseminated Intravascular Coagulation 9 1.0 1.0 no signal
943 Eye Pain 35 1.0 1.0 no signal
944 Renal Injury 19 1.0 1.0 no signal
945 Bone Density Decreased 20 1.0 1.0 no signal
946 Tinnitus 29 1.0 1.0 no signal
947 Agitation 46 1.0 1.0 no signal
948 Cognitive Disorder 29 1.0 1.0 no signal
949 Acute Respiratory Distress Syndrome 11 1.0 1.0 no signal
950 Affect Lability 6 1.0 1.0 no signal
951 Movement Disorder 20 1.0 1.0 no signal
952 Injection Site Induration 8 1.0 1.0 no signal
953 Abnormal Dreams 17 0.9 0.9 no signal
954 Inability To Afford Medication 6 0.9 0.9 no signal
955 Pharmaceutical Product Complaint 16 0.9 0.9 no signal
956 Cytomegalovirus Infection 10 0.9 0.9 no signal
957 Salivary Hypersecretion 6 0.9 0.9 no signal
958 Pneumocystis Jirovecii Pneumonia 6 0.9 0.9 no signal
959 Haemorrhage Intracranial 9 0.9 0.9 no signal
960 Rash Erythematous 28 0.9 0.9 no signal
961 Pruritus 225 0.9 0.9 no signal
962 Cardio-respiratory Arrest 25 0.9 0.9 no signal
963 Uveitis 8 0.9 0.9 no signal
964 Product Prescribing Issue 12 0.9 0.9 no signal
965 Cardiovascular Disorder 15 0.9 0.9 no signal
966 Hepatitis 15 0.9 0.9 no signal
967 Intentional Dose Omission 16 0.9 0.9 no signal
968 Circulatory Collapse 10 0.9 0.9 no signal
969 Electrocardiogram Qt Prolonged 21 0.9 0.9 no signal
970 Lymphoma 9 0.9 0.9 no signal
971 Device Malfunction 39 0.9 0.9 no signal
972 Accidental Overdose 21 0.9 0.9 no signal
973 Restlessness 21 0.9 0.9 no signal
974 Lip Swelling 19 0.9 0.9 no signal
975 Respiratory Depression 7 0.9 0.9 no signal
976 Intentional Drug Misuse 12 0.9 0.9 no signal
977 Lymphocyte Count Decreased 10 0.9 0.9 no signal
978 Muscle Spasticity 7 0.9 0.9 no signal
979 Blood Lactate Dehydrogenase Increased 9 0.9 0.9 no signal
980 Mood Swings 18 0.9 0.9 no signal
981 Tardive Dyskinesia 16 0.9 0.9 no signal
982 Injection Site Extravasation 7 0.9 0.9 no signal
983 Cardiogenic Shock 8 0.9 0.9 no signal
984 Impaired Work Ability 12 0.9 0.9 no signal
985 Skin Haemorrhage 8 0.9 0.9 no signal
986 Myelodysplastic Syndrome 8 0.9 0.9 no signal
987 Lower Respiratory Tract Infection 25 0.8 0.8 no signal
988 Product Administration Error 11 0.8 0.8 no signal
989 Photosensitivity Reaction 9 0.8 0.8 no signal
990 Drug Administration Error 17 0.8 0.8 no signal
991 Mydriasis 7 0.8 0.8 no signal
992 Diabetic Ketoacidosis 13 0.8 0.8 no signal
993 Middle Insomnia 10 0.8 0.8 no signal
994 Face Oedema 9 0.8 0.8 no signal
995 Shock 12 0.8 0.8 no signal
996 Coma 25 0.8 0.8 no signal
997 Seizure 60 0.8 0.8 no signal
998 Feeling Hot 32 0.8 0.8 no signal
999 Tachypnoea 7 0.8 0.8 no signal
1000 Delusion 8 0.8 0.8 no signal
1001 Thrombotic Microangiopathy 5 0.8 0.8 no signal
1002 Sexual Dysfunction 6 0.8 0.8 no signal
1003 Parkinsonism 5 0.8 0.8 no signal
1004 Cardiac Failure 41 0.8 0.8 no signal
1005 Intentional Product Misuse 44 0.8 0.8 no signal
1006 Multiple Sclerosis 24 0.8 0.8 no signal
1007 Disturbance In Attention 27 0.8 0.8 no signal
1008 Brain Injury 5 0.8 0.8 no signal
1009 Skin Reaction 7 0.8 0.8 no signal
1010 Spinal Operation 6 0.8 0.8 no signal
1011 Thyroid Cancer 6 0.8 0.8 no signal
1012 Mental Impairment 12 0.8 0.8 no signal
1013 Pregnancy 10 0.8 0.8 no signal
1014 Injection Site Rash 15 0.8 0.8 no signal
1015 Hypothermia 5 0.8 0.8 no signal
1016 Incorrect Product Administration Duration 10 0.8 0.8 no signal
1017 Inappropriate Antidiuretic Hormone Secretion 5 0.8 0.8 no signal
1018 Generalised Tonic-clonic Seizure 8 0.8 0.8 no signal
1019 Injection Site Swelling 37 0.8 0.8 no signal
1020 Mania 8 0.7 0.7 no signal
1021 Drug-induced Liver Injury 15 0.7 0.7 no signal
1022 Scratch 5 0.7 0.7 no signal
1023 Thinking Abnormal 9 0.7 0.7 no signal
1024 Mood Altered 13 0.7 0.7 no signal
1025 Hereditary Angioedema 5 0.7 0.7 no signal
1026 Lacrimation Increased 14 0.7 0.7 no signal
1027 Respiratory Arrest 13 0.7 0.7 no signal
1028 Injection Site Reaction 32 0.7 0.7 no signal
1029 Prescribed Overdose 9 0.7 0.7 no signal
1030 Product Prescribing Error 11 0.7 0.7 no signal
1031 Ocular Discomfort 5 0.7 0.7 no signal
1032 Sedation 12 0.7 0.7 no signal
1033 Nightmare 16 0.7 0.7 no signal
1034 Adverse Event 42 0.7 0.7 no signal
1035 Hepatic Cancer 11 0.7 0.7 no signal
1036 Abnormal Behaviour 18 0.7 0.7 no signal
1037 Hepatotoxicity 10 0.7 0.7 no signal
1038 Urticaria 75 0.7 0.7 no signal
1039 Ischaemic Stroke 8 0.7 0.7 no signal
1040 Pain Of Skin 12 0.7 0.7 no signal
1041 Anger 15 0.7 0.7 no signal
1042 Disease Recurrence 21 0.7 0.7 no signal
1043 Crying 16 0.7 0.7 no signal
1044 Injection Site Warmth 9 0.7 0.7 no signal
1045 Unintentional Medical Device Removal 5 0.7 0.7 no signal
1046 Erectile Dysfunction 11 0.7 0.7 no signal
1047 Breast Cancer Stage I 4 0.7 0.7 no signal
1048 Drug Effect Less Than Expected 6 0.7 0.7 no signal
1049 Vaginal Haemorrhage 18 0.7 0.7 no signal
1050 Fracture 8 0.7 0.7 no signal
1051 Deafness 11 0.6 0.6 no signal
1052 Emotional Distress 51 0.6 0.6 no signal
1053 Product Dispensing Error 9 0.6 0.6 no signal
1054 Anosmia 6 0.6 0.6 no signal
1055 Injection Site Urticaria 10 0.6 0.6 no signal
1056 Libido Decreased 5 0.6 0.6 no signal
1057 Product Physical Issue 8 0.6 0.6 no signal
1058 Injury Associated With Device 8 0.6 0.6 no signal
1059 Underdose 29 0.6 0.6 no signal
1060 Bone Loss 6 0.6 0.6 no signal
1061 Eye Irritation 22 0.6 0.6 no signal
1062 Epilepsy 12 0.6 0.6 no signal
1063 Suicidal Ideation 36 0.6 0.6 no signal
1064 Helicobacter Infection 4 0.6 0.6 no signal
1065 Bone Marrow Failure 8 0.6 0.6 no signal
1066 Euphoric Mood 4 0.6 0.6 no signal
1067 Injection Site Discomfort 4 0.6 0.6 no signal
1068 Angioedema 17 0.6 0.6 no signal
1069 C-reactive Protein Increased 14 0.6 0.6 no signal
1070 Drug Ineffective For Unapproved Indication 21 0.6 0.6 no signal
1071 Drug Administered At Inappropriate Site 4 0.6 0.6 no signal
1072 Psychotic Disorder 11 0.6 0.6 no signal
1073 Akathisia 5 0.6 0.6 no signal
1074 Pericarditis 6 0.6 0.6 no signal
1075 Withdrawal Syndrome 15 0.5 0.5 no signal
1076 Psoriasis 46 0.5 0.5 no signal
1077 Prescribed Underdose 7 0.5 0.5 no signal
1078 Hepatic Function Abnormal 13 0.5 0.5 no signal
1079 Incorrect Drug Administration Duration 10 0.5 0.5 no signal
1080 Therapeutic Response Decreased 21 0.5 0.5 no signal
1081 Hyperthyroidism 5 0.5 0.5 no signal
1082 Medication Error 19 0.5 0.5 no signal
1083 Neuroleptic Malignant Syndrome 4 0.5 0.5 no signal
1084 Drug Interaction 53 0.5 0.5 no signal
1085 Renal Cancer 16 0.5 0.5 no signal
1086 Product Use In Unapproved Indication 80 0.5 0.5 no signal
1087 Gastrointestinal Carcinoma 3 0.5 0.5 no signal
1088 Product Quality Issue 44 0.5 0.5 no signal
1089 Drug Dispensing Error 5 0.5 0.5 no signal
1090 Device Dislocation 14 0.5 0.5 no signal
1091 Cytokine Release Syndrome 6 0.5 0.5 no signal
1092 Anaphylactic Shock 8 0.5 0.5 no signal
1093 Intraocular Pressure Increased 4 0.5 0.5 no signal
1094 Tuberculosis 4 0.5 0.5 no signal
1095 Interstitial Lung Disease 15 0.5 0.5 no signal
1096 Sleep Disorder Due To A General Medical Condition 5 0.5 0.5 no signal
1097 Decreased Immune Responsiveness 3 0.5 0.5 no signal
1098 Psychomotor Hyperactivity 5 0.5 0.5 no signal
1099 Abortion Spontaneous 12 0.5 0.5 no signal
1100 Eczema 15 0.5 0.5 no signal
1101 Peritonitis Bacterial 3 0.5 0.5 no signal
1102 Device Use Error 10 0.5 0.5 no signal
1103 Application Site Rash 4 0.4 0.4 no signal
1104 Product Odour Abnormal 3 0.4 0.4 no signal
1105 Wrong Technique In Product Usage Process 57 0.4 0.4 no signal
1106 Aggression 14 0.4 0.4 no signal
1107 Glycosylated Haemoglobin Increased 7 0.4 0.4 no signal
1108 Gastric Cancer 7 0.4 0.4 no signal
1109 Expired Product Administered 9 0.4 0.4 no signal
1110 Overdose 57 0.4 0.4 no signal
1111 Drug Prescribing Error 5 0.4 0.4 no signal
1112 Breast Cancer 24 0.4 0.4 no signal
1113 Therapeutic Response Shortened 8 0.4 0.4 no signal
1114 Menorrhagia 5 0.4 0.4 no signal
1115 Extra Dose Administered 10 0.4 0.4 no signal
1116 Multiple Sclerosis Relapse 17 0.4 0.4 no signal
1117 Hepatitis C 3 0.4 0.4 no signal
1118 Product Substitution Issue 14 0.4 0.4 no signal
1119 Extrapyramidal Disorder 6 0.4 0.4 no signal
1120 Skin Burning Sensation 17 0.4 0.4 no signal
1121 Circumstance Or Information Capable Of Leading To Medication Error 8 0.4 0.4 no signal
1122 Drug Withdrawal Syndrome 21 0.4 0.4 no signal
1123 Device Leakage 10 0.4 0.4 no signal
1124 Dysmenorrhoea 3 0.4 0.4 no signal
1125 Exposure During Pregnancy 14 0.3 0.3 no signal
1126 Psoriatic Arthropathy 9 0.3 0.3 no signal
1127 Breast Cancer Female 6 0.3 0.3 no signal
1128 Toxicity To Various Agents 36 0.3 0.3 no signal
1129 Suicide Attempt 13 0.3 0.3 no signal
1130 Serotonin Syndrome 4 0.3 0.3 no signal
1131 Device Adhesion Issue 3 0.3 0.3 no signal
1132 Gynaecomastia 6 0.3 0.3 no signal
1133 Sickle Cell Anaemia With Crisis 3 0.3 0.3 no signal
1134 Premature Delivery 3 0.3 0.3 no signal
1135 Prostate Cancer 15 0.3 0.3 no signal
1136 Drug Dependence 29 0.3 0.3 no signal
1137 Skin Irritation 8 0.3 0.3 no signal
1138 No Adverse Event 29 0.3 0.3 no signal
1139 Incorrect Dose Administered By Device 4 0.2 0.2 no signal
1140 Completed Suicide 13 0.2 0.2 no signal
1141 Dystonia 3 0.2 0.2 no signal
1142 Device Breakage 6 0.2 0.2 no signal
1143 Drug Exposure During Pregnancy 5 0.2 0.2 no signal
1144 Product Preparation Error 3 0.2 0.2 no signal
1145 Product Adhesion Issue 5 0.2 0.2 no signal
1146 Incorrect Route Of Drug Administration 5 0.2 0.2 no signal
1147 Exposure Via Skin Contact 3 0.2 0.2 no signal
1148 Application Site Pruritus 3 0.2 0.2 no signal
1149 Drug Abuse 11 0.2 0.2 no signal
1150 Wrong Technique In Device Usage Process 6 0.2 0.2 no signal
1151 Colorectal Cancer 6 0.2 0.2 no signal
1152 Bladder Cancer 7 0.2 0.2 no signal
1153 Product Storage Error 10 0.2 0.2 no signal
1154 Device Delivery System Issue 3 0.2 0.2 no signal
1155 Application Site Erythema 3 0.2 0.2 no signal
1156 Oesophageal Carcinoma 3 0.2 0.2 no signal
1157 Myelosuppression 3 0.1 0.1 no signal
1158 Device Difficult To Use 5 0.1 0.1 no signal