OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Norepinephrine

1,020 flagged reaction(s) · 45,323 total co-reports · max PRR 2,615.2
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Appendicolith 215 2,615.2 2,669.2 signal
2 Sleep Disorder Therapy 66 1,088.5 1,095.3 signal
3 Antacid Therapy 41 1,023.0 1,027.0 signal
4 Vitamin B1 Increased 13 903.6 904.7 signal
5 Electrocardiogram T Wave Alternans 12 753.4 754.2 signal
6 Schizencephaly 11 648.7 649.4 signal
7 Diabetic Macroangiopathy 7 544.9 545.3 signal
8 Analgesic Therapy 64 521.2 524.3 signal
9 Drug Therapy 60 456.1 458.7 signal
10 Cerebral Haemorrhage Foetal 11 436.9 437.3 signal
11 Blood Lactic Acid Decreased 30 414.1 415.3 signal
12 Cardiac Output Increased 28 386.5 387.5 signal
13 Covid-19 Treatment 11 375.6 376.0 signal
14 Systolic Anterior Motion Of Mitral Valve 12 328.9 329.3 signal
15 Myoglobin Urine Present 35 321.3 322.4 signal
16 Anticoagulant Therapy 38 313.4 314.5 signal
17 Vitamin B1 Decreased 32 289.7 290.5 signal
18 Myocardial Calcification 13 248.0 248.3 signal
19 Sigmoid Sinus Thrombosis 7 243.3 243.4 signal
20 Bacteroides Infection 28 239.0 239.6 signal
21 Propofol Infusion Syndrome 73 227.7 229.2 signal
22 Malignant Melanoma Stage 0 18 217.6 218.0 signal
23 Burkholderia Test Positive 12 210.4 210.6 signal
24 Electrocardiogram U Wave Present 6 208.5 208.6 signal
25 Congenital Hiatus Hernia 21 206.4 206.8 signal
26 Left Ventricle Outflow Tract Obstruction 29 178.6 179.1 signal
27 Adrenergic Syndrome 6 157.8 157.9 signal
28 Vasoplegia Syndrome 117 154.2 155.9 signal
29 Cafe Au Lait Spots 7 153.1 153.2 signal
30 Hyperdynamic Left Ventricle 16 136.6 136.8 signal
31 Myoglobinaemia 7 123.8 123.9 signal
32 Vascular Resistance Systemic Decreased 8 123.6 123.7 signal
33 Blood Phosphorus Increased 142 108.5 109.9 signal
34 Pulmonary Haematoma 6 106.2 106.2 signal
35 Dry Gangrene 32 105.0 105.3 signal
36 Genital Erosion 14 99.4 99.6 signal
37 Drug-device Interaction 5 97.3 97.4 signal
38 Anion Gap 29 93.6 93.9 signal
39 Pulmonary Hypertensive Crisis 12 93.0 93.1 signal
40 Myocardial Stunning 6 91.9 92.0 signal
41 Acid Base Balance Abnormal 10 90.9 91.0 signal
42 Hyperphosphataemia 93 90.5 91.3 signal
43 Distributive Shock 82 76.0 76.6 signal
44 Cardiogenic Shock 525 75.4 79.2 signal
45 Hyperlactacidaemia 96 74.5 75.2 signal
46 Respiratory Gas Exchange Disorder 13 71.7 71.8 signal
47 Myocardial Depression 8 68.0 68.0 signal
48 Phaeochromocytoma Crisis 7 67.4 67.5 signal
49 Antibiotic Level Above Therapeutic 13 66.2 66.3 signal
50 Mean Arterial Pressure Decreased 8 64.1 64.1 signal
51 Renal Cortical Necrosis 7 61.9 62.0 signal
52 Systolic Dysfunction 32 61.8 62.0 signal
53 Kidney Duplex 7 60.0 60.1 signal
54 Human Herpesvirus 6 Infection Reactivation 10 58.4 58.5 signal
55 Pharyngeal Haemorrhage 35 57.4 57.6 signal
56 Cutaneous Mucormycosis 5 56.9 56.9 signal
57 Cytotoxic Oedema 7 53.4 53.5 signal
58 Locked-in Syndrome 12 53.0 53.0 signal
59 Diabetes Insipidus 62 51.8 52.1 signal
60 Gastrointestinal Ischaemia 7 51.0 51.1 signal
61 Multiple Organ Dysfunction Syndrome 680 49.3 52.6 signal
62 Haemodynamic Instability 182 49.1 49.9 signal
63 Electrocardiogram P Wave Abnormal 6 48.9 48.9 signal
64 Bronchopulmonary Aspergillosis Allergic 22 48.5 48.6 signal
65 Pneumonitis Aspiration 8 47.9 47.9 signal
66 Appendicitis 220 47.8 48.8 signal
67 Laryngomalacia 8 47.8 47.8 signal
68 Disseminated Mucormycosis 9 46.8 46.9 signal
69 Disseminated Strongyloidiasis 5 46.8 46.8 signal
70 Extremity Necrosis 40 46.0 46.2 signal
71 Ventricular Fibrillation 249 45.1 46.2 signal
72 Csf Pressure Increased 6 44.9 44.9 signal
73 Tuberculosis Gastrointestinal 7 44.5 44.5 signal
74 Foetal Exposure During Delivery 15 44.2 44.2 signal
75 Pulseless Electrical Activity 91 44.0 44.3 signal
76 Peripheral Ischaemia 89 43.8 44.2 signal
77 Necrosis Ischaemic 10 43.5 43.6 signal
78 Bronchopulmonary Dysplasia 17 42.7 42.8 signal
79 Methaemoglobinaemia 48 42.0 42.2 signal
80 Clostridial Sepsis 5 41.9 42.0 signal
81 Ischaemic Hepatitis 28 41.7 41.8 signal
82 Electrocardiogram T Wave Amplitude Decreased 7 40.9 40.9 signal
83 Total Lung Capacity Decreased 32 40.2 40.3 signal
84 Maternal Exposure During Delivery 19 39.3 39.4 signal
85 Vasoconstriction 17 39.3 39.4 signal
86 Myocardial Injury 19 38.4 38.5 signal
87 Pneumonia Necrotising 12 37.5 37.6 signal
88 Stress Cardiomyopathy 108 37.5 37.9 signal
89 Blindness Cortical 9 37.0 37.1 signal
90 Necrotising Oesophagitis 9 36.8 36.8 signal
91 Symmetrical Drug-related Intertriginous And Flexural Exanthema 14 35.4 35.5 signal
92 Mucosal Erosion 16 35.4 35.5 signal
93 Electrocardiogram Qrs Complex Prolonged 90 35.3 35.6 signal
94 Acute Lung Injury 21 35.3 35.4 signal
95 Iron Deficiency 78 35.2 35.5 signal
96 Shock 395 34.7 36.0 signal
97 Compartment Syndrome 45 34.6 34.8 signal
98 Dilatation Intrahepatic Duct Acquired 5 34.6 34.6 signal
99 Anion Gap Increased 23 34.4 34.5 signal
100 Ventricular Hypokinesia 55 34.3 34.4 signal
101 Blood Uric Acid Increased 97 33.7 34.0 signal
102 Device Computer Issue 5 33.2 33.2 signal
103 Symptom Masked 12 33.1 33.2 signal
104 Abdominal Compartment Syndrome 10 32.2 32.2 signal
105 Activated Partial Thromboplastin Time Prolonged 81 31.9 32.2 signal
106 Reversible Cerebral Vasoconstriction Syndrome 31 31.7 31.7 signal
107 Electrocardiogram Repolarisation Abnormality 12 30.5 30.6 signal
108 Procedural Hypotension 13 30.4 30.4 signal
109 Ear Malformation 7 29.9 30.0 signal
110 Unmasking Of Previously Unidentified Disease 16 29.8 29.9 signal
111 Hyperthermia Malignant 22 29.8 29.9 signal
112 Limb Amputation 6 29.8 29.8 signal
113 Wolff-parkinson-white Syndrome 7 29.6 29.6 signal
114 Lung Opacity 38 29.5 29.6 signal
115 Brash Syndrome 20 29.5 29.6 signal
116 Drug Effect Prolonged 8 28.6 28.6 signal
117 Mechanical Ileus 8 28.2 28.2 signal
118 Jarisch-herxheimer Reaction 10 28.0 28.0 signal
119 Laboratory Test Interference 11 28.0 28.0 signal
120 Left Ventricular Dilatation 7 28.0 28.0 signal
121 Apallic Syndrome 10 27.4 27.4 signal
122 Lower Respiratory Tract Infection Bacterial 7 27.2 27.2 signal
123 Local Anaesthetic Systemic Toxicity 14 27.0 27.0 signal
124 Hypophosphataemia 99 26.9 27.2 signal
125 Respiratory Tract Haemorrhage 8 26.8 26.8 signal
126 Neurodevelopmental Disorder 9 26.5 26.5 signal
127 Troponin Increased 100 26.5 26.7 signal
128 Myasthenia Gravis 104 26.4 26.6 signal
129 Electrocardiogram Qrs Complex Shortened 5 26.3 26.3 signal
130 Acidosis 100 26.1 26.3 signal
131 Anal Stenosis 7 26.0 26.1 signal
132 Aortic Stenosis 45 25.8 25.9 signal
133 Acute Respiratory Distress Syndrome 227 25.6 26.2 signal
134 Delayed Graft Function 9 25.4 25.4 signal
135 Neonatal Asphyxia 9 25.3 25.4 signal
136 Electrocardiogram St Segment Depression 28 25.3 25.4 signal
137 Hypoperfusion 13 24.8 24.9 signal
138 Sepsis Neonatal 10 24.8 24.8 signal
139 Apgar Score Low 16 24.7 24.7 signal
140 Brain Death 38 24.4 24.5 signal
141 Non-cardiogenic Pulmonary Oedema 13 24.4 24.5 signal
142 Subcutaneous Emphysema 12 24.4 24.4 signal
143 Motor Developmental Delay 7 24.2 24.3 signal
144 Fungal Sepsis 10 23.8 23.8 signal
145 Heparin-induced Thrombocytopenia 59 23.8 23.9 signal
146 Electrocardiogram St Segment Elevation 39 23.4 23.5 signal
147 Retinal Ischaemia 7 23.3 23.3 signal
148 Intestinal Ischaemia 64 23.3 23.4 signal
149 Metabolic Acidosis 364 22.9 23.7 signal
150 Respiratory Acidosis 45 22.9 23.0 signal
151 Dysbiosis 9 22.4 22.4 signal
152 Phimosis 8 22.2 22.2 signal
153 Acinetobacter Infection 12 22.1 22.1 signal
154 Blood Magnesium Increased 10 22.1 22.1 signal
155 Clostridium Test Positive 24 21.9 22.0 signal
156 Toxic Epidermal Necrolysis 163 21.6 21.9 signal
157 Serratia Infection 8 21.5 21.5 signal
158 Septic Shock 454 20.9 21.8 signal
159 Coma Scale Abnormal 30 20.9 20.9 signal
160 Nodal Arrhythmia 9 20.7 20.7 signal
161 Hypercapnia 31 20.7 20.7 signal
162 Cytokine Storm 7 20.5 20.5 signal
163 Lactic Acidosis 326 20.2 20.9 signal
164 Oliguria 63 20.2 20.3 signal
165 Perforation 8 20.0 20.1 signal
166 Ventricular Arrhythmia 36 19.6 19.7 signal
167 Amylase Increased 36 19.6 19.6 signal
168 Atrioventricular Block First Degree 42 19.2 19.3 signal
169 Nodal Rhythm 14 19.0 19.0 signal
170 Toxic Encephalopathy 47 19.0 19.0 signal
171 Hypoxic-ischaemic Encephalopathy 25 18.9 19.0 signal
172 Mucormycosis 24 18.6 18.6 signal
173 Product Ineffective For Unapproved Use 13 18.5 18.5 signal
174 Cardiovascular Insufficiency 15 18.4 18.4 signal
175 Ventricular Tachycardia 153 18.4 18.6 signal
176 Ischaemia 42 18.1 18.1 signal
177 Anuria 78 17.9 18.1 signal
178 Patent Ductus Arteriosus 35 17.4 17.5 signal
179 Pulmonary Valve Stenosis 7 17.3 17.3 signal
180 Ascites 255 17.2 17.6 signal
181 Arteriospasm Coronary 34 17.1 17.2 signal
182 Dilated Cardiomyopathy 8 17.1 17.1 signal
183 Infantile Apnoea 7 17.1 17.1 signal
184 Pupil Fixed 15 17.1 17.1 signal
185 Pulse Absent 41 17.1 17.2 signal
186 Fanconi Syndrome 12 17.0 17.0 signal
187 Developmental Hip Dysplasia 7 16.7 16.7 signal
188 Fungaemia 13 16.5 16.5 signal
189 Cerebellar Infarction 14 16.5 16.5 signal
190 Pericardial Haemorrhage 18 16.3 16.4 signal
191 Anticholinergic Syndrome 13 16.2 16.2 signal
192 Pneumatosis Intestinalis 23 16.1 16.1 signal
193 Continuous Haemodiafiltration 8 16.0 16.0 signal
194 Electrocardiogram Pr Prolongation 6 15.9 15.9 signal
195 Bezoar 11 15.9 15.9 signal
196 Klebsiella Sepsis 9 15.9 15.9 signal
197 Gastrointestinal Necrosis 23 15.8 15.8 signal
198 Serotonin Syndrome 151 15.7 15.9 signal
199 Critical Illness 6 15.5 15.5 signal
200 Circulatory Collapse 131 15.2 15.4 signal
201 Product Contamination Microbial 9 15.2 15.2 signal
202 Haematoma Muscle 9 15.2 15.2 signal
203 Haemoperitoneum 6 15.2 15.2 signal
204 Colour Blindness 7 15.1 15.1 signal
205 Klebsiella Infection 38 15.0 15.1 signal
206 Blood Fibrinogen Increased 6 15.0 15.0 signal
207 Pyelocaliectasis 7 14.9 14.9 signal
208 Embolism Arterial 9 14.9 14.9 signal
209 Acute Left Ventricular Failure 5 14.7 14.7 signal
210 Hypervolaemia 35 14.5 14.5 signal
211 Blood Lactic Acid Increased 38 14.4 14.5 signal
212 Haemothorax 21 14.4 14.4 signal
213 Respiratory Depression 88 14.3 14.4 signal
214 Myoglobin Blood Increased 11 14.2 14.3 signal
215 Disseminated Intravascular Coagulation 99 13.9 14.0 signal
216 Intestinal Pseudo-obstruction 6 13.8 13.8 signal
217 Nephrogenic Diabetes Insipidus 8 13.8 13.8 signal
218 Gangrene 42 13.7 13.8 signal
219 Low Birth Weight Baby 55 13.7 13.8 signal
220 Metabolic Alkalosis 11 13.7 13.7 signal
221 Systemic Candida 17 13.7 13.7 signal
222 Antiphospholipid Syndrome 11 13.7 13.7 signal
223 Pleuritic Pain 19 13.6 13.6 signal
224 Rash Morbilliform 19 13.6 13.6 signal
225 Cardiac Output Decreased 6 13.6 13.6 signal
226 Right Ventricular Failure 48 13.5 13.5 signal
227 Strongyloidiasis 11 13.5 13.5 signal
228 Wrong Product Administered 45 13.5 13.5 signal
229 Cardiac Arrest 561 13.4 14.1 signal
230 Livedo Reticularis 14 13.3 13.3 signal
231 Candida Sepsis 6 13.2 13.2 signal
232 Enterococcal Bacteraemia 7 13.2 13.2 signal
233 Muscle Necrosis 6 13.1 13.1 signal
234 Drug Reaction With Eosinophilia And Systemic Symptoms 168 13.1 13.2 signal
235 Incorrect Route Of Product Administration 108 12.8 12.9 signal
236 Immune Effector Cell-associated Neurotoxicity Syndrome 36 12.7 12.8 signal
237 Megacolon 10 12.7 12.7 signal
238 Brain Herniation 19 12.6 12.6 signal
239 Bradypnoea 17 12.6 12.6 signal
240 Renal Tubular Necrosis 62 12.5 12.6 signal
241 Cryptorchism 7 12.4 12.4 signal
242 Pulmonary Sepsis 9 12.3 12.4 signal
243 Acute Generalised Exanthematous Pustulosis 48 12.3 12.4 signal
244 Coagulopathy 102 12.2 12.3 signal
245 Foetal Distress Syndrome 13 12.2 12.2 signal
246 Torsade De Pointes 48 12.1 12.2 signal
247 Optic Nerve Injury 7 12.1 12.1 signal
248 Procalcitonin Increased 7 12.0 12.0 signal
249 Bradycardia 320 12.0 12.3 signal
250 Pneumoperitoneum 11 11.9 11.9 signal
251 Pneumonia Klebsiella 11 11.9 11.9 signal
252 Vasodilatation 15 11.8 11.8 signal
253 Device Related Sepsis 12 11.7 11.7 signal
254 Brugada Syndrome 6 11.6 11.6 signal
255 Escherichia Test Positive 7 11.6 11.6 signal
256 Bacterial Infection 108 11.5 11.6 signal
257 Blood Ph Decreased 10 11.5 11.5 signal
258 Long Qt Syndrome 14 11.5 11.5 signal
259 Biliary Tract Disorder 8 11.5 11.5 signal
260 Acute Respiratory Failure 110 11.4 11.5 signal
261 Hypoxia 201 11.4 11.6 signal
262 Catheter Site Haemorrhage 14 11.3 11.3 signal
263 Cerebellar Atrophy 5 11.2 11.2 signal
264 Electrocardiogram Qt Prolonged 203 11.2 11.4 signal
265 Cardiotoxicity 50 11.2 11.2 signal
266 Pneumomediastinum 10 11.1 11.1 signal
267 Cerebellar Haemorrhage 8 11.1 11.1 signal
268 Right Ventricular Dysfunction 6 11.0 11.1 signal
269 Pseudomonas Infection 47 11.0 11.1 signal
270 Multi-organ Disorder 11 11.0 11.0 signal
271 Intentional Overdose 352 11.0 11.3 signal
272 Sinus Bradycardia 53 10.9 10.9 signal
273 Angle Closure Glaucoma 14 10.8 10.9 signal
274 Hypernatraemia 27 10.8 10.8 signal
275 Supraventricular Tachycardia 52 10.8 10.8 signal
276 Myoclonic Epilepsy 8 10.8 10.8 signal
277 Troponin I Increased 9 10.7 10.7 signal
278 Systemic Infection 9 10.7 10.7 signal
279 Tonic Clonic Movements 7 10.7 10.7 signal
280 Dacryostenosis Acquired 7 10.7 10.7 signal
281 Alpha Haemolytic Streptococcal Infection 5 10.7 10.7 signal
282 Cerebral Haematoma 18 10.6 10.7 signal
283 Metabolic Encephalopathy 16 10.6 10.6 signal
284 Extravasation 22 10.5 10.6 signal
285 Premature Delivery 85 10.5 10.6 signal
286 Fixed Eruption 9 10.5 10.5 signal
287 Kounis Syndrome 12 10.5 10.5 signal
288 Respiratory Failure 386 10.5 10.8 signal
289 Acute Kidney Injury 798 10.4 11.2 signal
290 Hypotonia Neonatal 8 10.4 10.4 signal
291 Hypotension 1,045 10.3 11.4 signal
292 Mechanical Ventilation 10 10.3 10.3 signal
293 Necrosis 29 10.3 10.3 signal
294 Splenic Infarction 9 10.3 10.3 signal
295 Shock Haemorrhagic 42 10.2 10.3 signal
296 Pseudomonal Sepsis 9 10.1 10.1 signal
297 Cardiomyopathy 75 10.0 10.1 signal
298 Bronchopulmonary Aspergillosis 39 10.0 10.0 signal
299 Leukocytosis 91 10.0 10.1 signal
300 Enterococcal Infection 24 9.8 9.8 signal
301 Electrocardiogram Abnormal 39 9.8 9.8 signal
302 Sepsis 552 9.8 10.3 signal
303 False Positive Investigation Result 5 9.8 9.8 signal
304 Consciousness Fluctuating 5 9.7 9.7 signal
305 Device Infusion Issue 12 9.7 9.7 signal
306 Pulmonary Arterial Pressure Increased 8 9.7 9.7 signal
307 Hyponatraemia 274 9.7 9.9 signal
308 Capillary Leak Syndrome 10 9.7 9.7 signal
309 Sinus Tachycardia 69 9.6 9.7 signal
310 Retroperitoneal Haemorrhage 12 9.6 9.6 signal
311 Renal Infarct 7 9.5 9.5 signal
312 Tachyarrhythmia 12 9.5 9.5 signal
313 Drug Clearance Decreased 6 9.4 9.4 signal
314 Cardiac Ventricular Thrombosis 6 9.4 9.4 signal
315 Hypothermia 48 9.4 9.4 signal
316 Troponin T Increased 6 9.3 9.4 signal
317 Hepatorenal Syndrome 8 9.3 9.4 signal
318 Left Ventricular Dysfunction 31 9.2 9.2 signal
319 Cardiac Dysfunction 17 9.2 9.2 signal
320 Coma 220 9.1 9.3 signal
321 Rhabdomyolysis 192 9.1 9.3 signal
322 Intra-abdominal Haemorrhage 11 9.1 9.1 signal
323 Pneumonia Staphylococcal 9 9.0 9.1 signal
324 Retroperitoneal Haematoma 10 9.0 9.0 signal
325 Arrhythmia Supraventricular 5 9.0 9.0 signal
326 Neonatal Respiratory Distress Syndrome 16 8.9 8.9 signal
327 Hyperthermia 34 8.9 8.9 signal
328 Systemic Inflammatory Response Syndrome 17 8.9 8.9 signal
329 Immune Thrombocytopenia 20 8.9 8.9 signal
330 Cytokine Release Syndrome 85 8.8 8.9 signal
331 Cholestasis 85 8.8 8.9 signal
332 Bundle Branch Block Left 19 8.8 8.8 signal
333 Cardiac Tamponade 21 8.7 8.7 signal
334 Intermittent Claudication 7 8.7 8.7 signal
335 Orthopnoea 14 8.7 8.7 signal
336 Diffuse Alveolar Damage 5 8.6 8.6 signal
337 Respiratory Alkalosis 7 8.6 8.6 signal
338 Drug Ineffective For Unapproved Indication 238 8.5 8.6 signal
339 Optic Atrophy 7 8.5 8.5 signal
340 Cardiac Failure Acute 28 8.3 8.4 signal
341 Chronic Respiratory Failure 5 8.3 8.3 signal
342 Hyperlipidaemia 50 8.3 8.3 signal
343 Tachypnoea 56 8.2 8.2 signal
344 Pneumonia Fungal 16 8.2 8.2 signal
345 Premature Baby 124 8.1 8.2 signal
346 Blood Calcium Increased 36 8.1 8.1 signal
347 Cardiopulmonary Failure 16 8.1 8.1 signal
348 Venoocclusive Liver Disease 20 8.1 8.1 signal
349 Breath Sounds Abnormal 20 8.0 8.0 signal
350 Benign Prostatic Hyperplasia 21 8.0 8.0 signal
351 Skin Necrosis 21 8.0 8.0 signal
352 Multi-organ Failure 70 7.9 7.9 signal
353 Necrotising Fasciitis 14 7.9 7.9 signal
354 Brain Oedema 50 7.8 7.9 signal
355 Vascular Stent Thrombosis 8 7.8 7.8 signal
356 Respiratory Symptom 11 7.8 7.8 signal
357 Toxicity To Various Agents 656 7.7 8.2 signal
358 End Stage Renal Disease 72 7.7 7.8 signal
359 Device Connection Issue 8 7.7 7.7 signal
360 Hyperkalaemia 136 7.7 7.8 signal
361 Colitis Ischaemic 26 7.7 7.7 signal
362 Coagulation Time Prolonged 6 7.6 7.6 signal
363 Pupillary Reflex Impaired 7 7.6 7.6 signal
364 Heart Valve Incompetence 11 7.6 7.6 signal
365 Autonomic Nervous System Imbalance 11 7.6 7.6 signal
366 Clostridial Infection 13 7.5 7.5 signal
367 Inhibitory Drug Interaction 6 7.5 7.5 signal
368 Hypertriglyceridaemia 22 7.5 7.5 signal
369 Graft Versus Host Disease In Gastrointestinal Tract 8 7.4 7.4 signal
370 Neuralgia 91 7.4 7.5 signal
371 Atrioventricular Block 29 7.4 7.4 signal
372 Bacteraemia 44 7.4 7.4 signal
373 Haemophagocytic Lymphohistiocytosis 27 7.4 7.4 signal
374 Areflexia 10 7.4 7.4 signal
375 Staphylococcal Bacteraemia 16 7.3 7.3 signal
376 Type Iv Hypersensitivity Reaction 10 7.3 7.3 signal
377 Generalised Tonic-clonic Seizure 60 7.3 7.3 signal
378 Bradyarrhythmia 6 7.2 7.2 signal
379 Fibrin D Dimer Increased 13 7.2 7.2 signal
380 Adrenocortical Insufficiency Acute 7 7.2 7.2 signal
381 Clonus 10 7.2 7.2 signal
382 Pathogen Resistance 33 7.2 7.2 signal
383 Hepatic Cytolysis 44 7.1 7.2 signal
384 Aspiration 39 7.1 7.1 signal
385 Electrocardiogram T Wave Inversion 8 7.1 7.1 signal
386 Pulmonary Alveolar Haemorrhage 20 7.1 7.1 signal
387 Oxygen Saturation Abnormal 10 7.1 7.1 signal
388 Cardiac Failure Chronic 15 7.0 7.0 signal
389 Cell Death 7 7.0 7.0 signal
390 Hyperbilirubinaemia 36 6.9 6.9 signal
391 Brain Injury 35 6.9 6.9 signal
392 Ventricular Dysfunction 9 6.9 6.9 signal
393 Drug Level Below Therapeutic 19 6.8 6.9 signal
394 Recalled Product 6 6.8 6.8 signal
395 Atrioventricular Block Complete 23 6.8 6.8 signal
396 Tumour Lysis Syndrome 30 6.8 6.8 signal
397 Stridor 10 6.7 6.7 signal
398 Encephalopathy 83 6.7 6.8 signal
399 Transaminases Increased 75 6.7 6.7 signal
400 Bacterial Sepsis 11 6.7 6.7 signal
401 Hypovolaemic Shock 16 6.6 6.7 signal
402 Liver Function Test Increased 71 6.6 6.6 signal
403 Pulmonary Oedema 148 6.5 6.6 signal
404 Escherichia Infection 27 6.5 6.5 signal
405 Tachycardia 292 6.5 6.7 signal
406 Conduction Disorder 6 6.5 6.5 signal
407 Rales 19 6.5 6.5 signal
408 Myoclonus 39 6.5 6.5 signal
409 Posterior Reversible Encephalopathy Syndrome 31 6.4 6.5 signal
410 Bundle Branch Block Right 15 6.4 6.4 signal
411 Anticoagulation Drug Level Above Therapeutic 5 6.4 6.4 signal
412 Hypertransaminasaemia 22 6.4 6.4 signal
413 Mydriasis 41 6.3 6.3 signal
414 Acute Hepatic Failure 43 6.3 6.3 signal
415 Depressed Level Of Consciousness 123 6.2 6.2 signal
416 Arterial Thrombosis 6 6.1 6.1 signal
417 Neurological Decompensation 7 6.1 6.1 signal
418 Pulmonary Haemorrhage 24 6.1 6.1 signal
419 Escherichia Urinary Tract Infection 13 6.1 6.1 signal
420 Immunosuppressant Drug Level Increased 10 6.0 6.0 signal
421 Hepatitis Fulminant 9 6.0 6.0 signal
422 Acute Pulmonary Oedema 17 6.0 6.0 signal
423 Staphylococcal Sepsis 15 6.0 6.0 signal
424 Haemangioma 7 6.0 6.0 signal
425 Ulcer 48 6.0 6.0 signal
426 Status Epilepticus 34 5.9 6.0 signal
427 Haemolysis 23 5.9 5.9 signal
428 Atrioventricular Block Second Degree 9 5.9 5.9 signal
429 Polycythaemia 6 5.8 5.8 signal
430 Therapy Non-responder 131 5.8 5.9 signal
431 Aspergillus Infection 19 5.8 5.8 signal
432 Brain Natriuretic Peptide Increased 9 5.8 5.8 signal
433 Hepatic Failure 88 5.8 5.8 signal
434 Dermatitis Exfoliative Generalised 10 5.8 5.8 signal
435 Blood Chloride Increased 5 5.7 5.7 signal
436 Blood Lactate Dehydrogenase Increased 46 5.7 5.7 signal
437 Pulmonary Congestion 38 5.7 5.7 signal
438 Atrial Flutter 23 5.7 5.7 signal
439 Inflammatory Marker Increased 14 5.6 5.7 signal
440 Stress 205 5.6 5.7 signal
441 Ileus 35 5.6 5.6 signal
442 Anaemia Macrocytic 6 5.6 5.6 signal
443 Procedural Haemorrhage 11 5.6 5.6 signal
444 Hyperammonaemia 14 5.5 5.5 signal
445 Product Packaging Issue 26 5.5 5.6 signal
446 Aortic Valve Stenosis 5 5.5 5.5 signal
447 Gout 50 5.5 5.5 signal
448 Nephrogenic Anaemia 13 5.5 5.5 signal
449 Device Alarm Issue 5 5.5 5.5 signal
450 Candida Infection 46 5.5 5.5 signal
451 Hepatotoxicity 61 5.4 5.5 signal
452 Urine Output Decreased 24 5.4 5.4 signal
453 Mitral Valve Incompetence 31 5.4 5.4 signal
454 Graft Versus Host Disease In Skin 6 5.4 5.4 signal
455 Thrombosis In Device 9 5.4 5.4 signal
456 Gastrointestinal Hypomotility 6 5.3 5.3 signal
457 Cardio-respiratory Arrest 113 5.3 5.4 signal
458 Pulmonary Hypertension 56 5.3 5.3 signal
459 Pseudomembranous Colitis 6 5.3 5.3 signal
460 Neutropenic Sepsis 19 5.2 5.3 signal
461 Drug Level Above Therapeutic 12 5.2 5.2 signal
462 Left Ventricular Failure 9 5.2 5.2 signal
463 Myocardial Ischaemia 30 5.2 5.2 signal
464 Drug Level Increased 43 5.1 5.1 signal
465 Diastolic Dysfunction 8 5.1 5.1 signal
466 Atelectasis 25 5.1 5.1 signal
467 Rash Maculo-papular 57 5.1 5.1 signal
468 Mental Status Changes 71 5.1 5.1 signal
469 Bronchiectasis 17 5.0 5.1 signal
470 Respiratory Distress 70 5.0 5.0 signal
471 Pneumonia Aspiration 63 5.0 5.0 signal
472 Blood Potassium Increased 41 5.0 5.0 signal
473 Acute Coronary Syndrome 21 5.0 5.0 signal
474 Euglycaemic Diabetic Ketoacidosis 10 5.0 5.0 signal
475 Ejection Fraction Decreased 39 5.0 5.0 signal
476 Lung Consolidation 7 4.9 4.9 signal
477 Blood Creatine Increased 11 4.9 4.9 signal
478 Thrombocytosis 9 4.9 4.9 signal
479 Covid-19 Pneumonia 29 4.8 4.8 signal
480 Delirium 84 4.8 4.8 signal
481 Speech Disorder Developmental 7 4.8 4.8 signal
482 Blood Test Abnormal 34 4.8 4.8 signal
483 Obstructive Airways Disorder 27 4.8 4.8 signal
484 Aspartate Aminotransferase Increased 128 4.8 4.8 signal
485 Diverticular Perforation 5 4.8 4.8 signal
486 Intraventricular Haemorrhage 6 4.8 4.8 signal
487 Sedation Complication 6 4.7 4.7 signal
488 General Physical Health Deterioration 275 4.7 4.8 signal
489 Hepatic Necrosis 9 4.7 4.7 signal
490 Alanine Aminotransferase Increased 146 4.7 4.7 signal
491 Erysipelas 12 4.7 4.7 signal
492 Disseminated Tuberculosis 6 4.7 4.7 signal
493 Dilatation Ventricular 5 4.6 4.6 signal
494 Abdominal Distension 244 4.6 4.7 signal
495 Cholestatic Liver Injury 5 4.6 4.6 signal
496 Blood Cholesterol Increased 108 4.6 4.6 signal
497 Prothrombin Time Prolonged 14 4.6 4.6 signal
498 Ventricular Extrasystoles 24 4.6 4.6 signal
499 Anaphylactic Shock 59 4.6 4.6 signal
500 Blood Creatine Phosphokinase Increased 67 4.5 4.5 signal
501 Venous Thrombosis 9 4.5 4.5 signal
502 Blood Creatinine Increased 149 4.5 4.6 signal
503 Multiple-drug Resistance 7 4.5 4.5 signal
504 Nystagmus 12 4.5 4.5 signal
505 Ileus Paralytic 10 4.4 4.5 signal
506 Eosinophilic Pneumonia 7 4.4 4.4 signal
507 Eosinophilia 39 4.4 4.4 signal
508 Hypovolaemia 13 4.4 4.4 signal
509 Small For Dates Baby 11 4.4 4.4 signal
510 Pneumonia Bacterial 20 4.3 4.3 signal
511 Paradoxical Drug Reaction 8 4.3 4.3 signal
512 Thrombocytopenia 241 4.3 4.3 signal
513 Ammonia Increased 11 4.3 4.3 signal
514 Nephropathy Toxic 24 4.3 4.3 signal
515 Posture Abnormal 7 4.3 4.3 signal
516 Endotracheal Intubation 6 4.2 4.2 signal
517 Drug Interaction 336 4.2 4.3 signal
518 Sputum Discoloured 20 4.2 4.2 signal
519 Nervous System Disorder 66 4.2 4.2 signal
520 Tumour Haemorrhage 6 4.2 4.2 signal
521 Blood Pressure Decreased 139 4.1 4.2 signal
522 Hypoalbuminaemia 16 4.1 4.1 signal
523 Chronic Obstructive Pulmonary Disease 109 4.1 4.2 signal
524 Pleural Effusion 127 4.1 4.2 signal
525 Pneumothorax 33 4.1 4.1 signal
526 Blood Urea Increased 35 4.1 4.1 signal
527 Escherichia Sepsis 6 4.1 4.1 signal
528 Clostridium Difficile Colitis 22 4.1 4.1 signal
529 Renal Impairment 173 4.1 4.1 signal
530 Blood Bilirubin Increased 56 4.1 4.1 signal
531 Mixed Liver Injury 6 4.1 4.1 signal
532 Unresponsive To Stimuli 53 4.1 4.1 signal
533 Altered State Of Consciousness 44 4.0 4.0 signal
534 Infarction 14 4.0 4.0 signal
535 Upper Gastrointestinal Haemorrhage 34 4.0 4.0 signal
536 Adrenal Insufficiency 24 4.0 4.0 signal
537 Haemodialysis 17 4.0 4.0 signal
538 Hyperreflexia 7 4.0 4.0 signal
539 Crepitations 6 3.9 4.0 signal
540 Foetal Exposure During Pregnancy 162 3.9 4.0 signal
541 Foetal Growth Restriction 12 3.9 3.9 signal
542 Jaundice Cholestatic 7 3.9 3.9 signal
543 Organ Failure 8 3.9 3.9 signal
544 Suicide Attempt 119 3.9 3.9 signal
545 Endocarditis 10 3.9 3.9 signal
546 Urosepsis 18 3.9 3.9 signal
547 Condition Aggravated 589 3.9 4.0 signal
548 Hypercalcaemia 24 3.8 3.9 signal
549 Portal Hypertension 6 3.8 3.8 signal
550 Cerebral Ischaemia 10 3.8 3.8 signal
551 Hypokalaemia 88 3.8 3.8 signal
552 Electrolyte Imbalance 22 3.8 3.8 signal
553 Respiratory Rate Decreased 6 3.8 3.8 signal
554 Congestive Cardiomyopathy 8 3.7 3.7 signal
555 Renal Failure 253 3.7 3.8 signal
556 Skin Warm 11 3.7 3.7 signal
557 Drug Ineffective 2,486 3.7 4.6 signal
558 Post Procedural Haemorrhage 22 3.7 3.7 signal
559 Anaesthetic Complication 5 3.7 3.7 signal
560 Poor Peripheral Circulation 8 3.7 3.7 signal
561 Pulmonary Embolism 178 3.7 3.7 signal
562 Subarachnoid Haemorrhage 19 3.7 3.7 signal
563 Polyuria 15 3.6 3.6 signal
564 Hypoventilation 6 3.6 3.6 signal
565 Dermatitis Bullous 13 3.6 3.6 signal
566 Generalised Oedema 22 3.5 3.5 signal
567 Coronary Artery Stenosis 9 3.5 3.5 signal
568 Autoimmune Haemolytic Anaemia 6 3.5 3.5 signal
569 Azotaemia 7 3.4 3.5 signal
570 Encephalitis 12 3.4 3.4 signal
571 Foetal Death 9 3.4 3.4 signal
572 Ventricular Septal Defect 10 3.4 3.4 signal
573 Aplastic Anaemia 9 3.4 3.4 signal
574 Intentional Product Misuse 148 3.4 3.4 signal
575 Thrombotic Thrombocytopenic Purpura 6 3.4 3.4 signal
576 Liver Injury 41 3.3 3.4 signal
577 Hypotonia 17 3.3 3.4 signal
578 Pre-eclampsia 8 3.3 3.3 signal
579 Micturition Urgency 19 3.3 3.3 signal
580 Stevens-johnson Syndrome 37 3.3 3.3 signal
581 Exposure During Pregnancy 103 3.3 3.3 signal
582 Incorrect Drug Administration Rate 7 3.3 3.3 signal
583 Hypoglycaemia 80 3.3 3.3 signal
584 Cholangitis 10 3.2 3.2 signal
585 Dry Mouth 131 3.2 3.2 signal
586 Transfusion 17 3.2 3.2 signal
587 Intracranial Pressure Increased 9 3.2 3.2 signal
588 Neurotoxicity 28 3.2 3.2 signal
589 Haemoptysis 45 3.2 3.2 signal
590 Pericardial Effusion 37 3.2 3.2 signal
591 Pneumocystis Jirovecii Pneumonia 16 3.2 3.2 signal
592 Maternal Exposure During Pregnancy 141 3.2 3.2 signal
593 Decubitus Ulcer 13 3.2 3.2 signal
594 Angiopathy 9 3.1 3.1 signal
595 Hepatic Function Abnormal 59 3.1 3.2 signal
596 Large Intestine Perforation 11 3.1 3.1 signal
597 Pulmonary Arterial Hypertension 23 3.1 3.1 signal
598 Rhinovirus Infection 6 3.1 3.1 signal
599 Staphylococcal Infection 52 3.1 3.1 signal
600 Clostridium Difficile Infection 34 3.1 3.1 signal
601 Agranulocytosis 29 3.1 3.1 signal
602 Embolism 13 3.1 3.1 signal
603 Thrombosis 125 3.1 3.1 signal
604 Blood Pressure Systolic Decreased 7 3.1 3.1 signal
605 Pulmonary Mass 23 3.1 3.1 signal
606 Febrile Neutropenia 101 3.0 3.0 signal
607 Mouth Haemorrhage 11 3.0 3.0 signal
608 Muscle Haemorrhage 6 3.0 3.0 signal
609 Fluid Overload 22 2.9 2.9 signal
610 Lower Gastrointestinal Haemorrhage 11 2.9 2.9 signal
611 Normal Newborn 8 2.9 2.9 signal
612 Anaphylactoid Reaction 6 2.9 2.9 signal
613 Diabetes Mellitus 112 2.9 2.9 signal
614 Guillain-barre Syndrome 7 2.9 2.9 signal
615 Leg Amputation 6 2.9 2.9 signal
616 Peritonitis 30 2.9 2.9 signal
617 Cardiovascular Disorder 37 2.9 2.9 signal
618 Live Birth 12 2.8 2.8 signal
619 Drug Resistance 37 2.8 2.9 signal
620 Anaphylactic Reaction 79 2.8 2.9 signal
621 Hyperglycaemia 52 2.8 2.8 signal
622 Hypocalcaemia 27 2.8 2.8 signal
623 Overdose 309 2.8 2.9 signal
624 Full Blood Count Abnormal 15 2.8 2.8 signal
625 Hypophagia 36 2.8 2.8 signal
626 Cholecystitis Acute 8 2.8 2.8 signal
627 Abdominal Tenderness 7 2.8 2.8 signal
628 Dialysis 20 2.8 2.8 signal
629 Aortic Valve Incompetence 6 2.8 2.8 signal
630 Product Administration Error 28 2.8 2.8 signal
631 Post Transplant Lymphoproliferative Disorder 7 2.8 2.8 signal
632 Cardiac Failure 112 2.8 2.8 signal
633 Abortion Induced 13 2.7 2.7 signal
634 Drug Level Decreased 14 2.7 2.7 signal
635 Injection Site Extravasation 17 2.7 2.7 signal
636 Acute Myocardial Infarction 40 2.7 2.7 signal
637 Product Use In Unapproved Indication 330 2.7 2.7 signal
638 Lung Infiltration 12 2.7 2.7 signal
639 Neuroleptic Malignant Syndrome 16 2.7 2.7 signal
640 Muscle Rigidity 16 2.6 2.6 signal
641 Intestinal Perforation 15 2.6 2.6 signal
642 Haemolytic Anaemia 12 2.6 2.6 signal
643 Hepatitis Cholestatic 8 2.6 2.6 signal
644 Haemorrhage Intracranial 20 2.6 2.6 signal
645 Off Label Use 1,155 2.6 2.8 signal
646 Myocarditis 15 2.6 2.6 signal
647 Hypokinesia 19 2.6 2.6 signal
648 Overweight 7 2.6 2.6 signal
649 International Normalised Ratio Increased 37 2.5 2.5 signal
650 Abdominal Pain 298 2.5 2.6 signal
651 Atrial Fibrillation 125 2.5 2.5 signal
652 Lymphopenia 18 2.5 2.5 signal
653 Duodenal Ulcer 9 2.5 2.5 signal
654 Haemorrhagic Stroke 10 2.5 2.5 signal
655 Tricuspid Valve Incompetence 10 2.5 2.5 signal
656 Renal Failure Acute 54 2.5 2.5 signal
657 Hypertensive Crisis 14 2.5 2.5 signal
658 Paralysis 18 2.5 2.5 signal
659 Conjunctivitis 23 2.5 2.5 signal
660 Blood Disorder 10 2.5 2.5 signal
661 Glomerular Filtration Rate Decreased 15 2.4 2.4 signal
662 Labelled Drug-drug Interaction Medication Error 11 2.4 2.4 signal
663 Haematoma 32 2.4 2.4 signal
664 Enterocolitis 7 2.4 2.4 signal
665 Arrhythmia 58 2.4 2.4 signal
666 Sleep Disorder 85 2.4 2.4 signal
667 Seizure 139 2.4 2.4 signal
668 Metabolic Disorder 7 2.4 2.4 signal
669 Accidental Overdose 44 2.4 2.4 signal
670 Anaemia 228 2.4 2.4 signal
671 Toxic Skin Eruption 12 2.3 2.3 signal
672 Cerebral Infarction 29 2.3 2.3 signal
673 Leukopenia 59 2.3 2.3 signal
674 Diffuse Large B-cell Lymphoma 9 2.3 2.3 signal
675 Body Temperature Increased 24 2.3 2.3 signal
676 Procedural Complication 9 2.3 2.3 signal
677 Pancytopenia 65 2.3 2.3 signal
678 Dermatitis Acneiform 7 2.3 2.3 no signal
679 Congenital Anomaly 9 2.3 2.3 signal
680 Myopathy 10 2.3 2.3 signal
681 Pulmonary Fibrosis 22 2.3 2.3 signal
682 Inguinal Hernia 7 2.3 2.3 no signal
683 Cytomegalovirus Infection 19 2.3 2.3 signal
684 Cyanosis 18 2.3 2.3 signal
685 Cardiomegaly 14 2.2 2.2 signal
686 Infusion Site Extravasation 7 2.2 2.2 no signal
687 Hepatocellular Injury 16 2.2 2.2 signal
688 Transplant Rejection 9 2.2 2.2 signal
689 Hepatomegaly 11 2.2 2.2 signal
690 Agitation 82 2.2 2.2 signal
691 Chromaturia 25 2.2 2.2 signal
692 Hydrocephalus 6 2.2 2.2 no signal
693 Enteritis 7 2.2 2.2 no signal
694 Mouth Ulceration 23 2.2 2.2 signal
695 Swelling 102 2.2 2.2 signal
696 Motor Dysfunction 11 2.1 2.1 signal
697 Constipation 235 2.1 2.2 signal
698 Somnolence 218 2.1 2.2 signal
699 Acute Graft Versus Host Disease 5 2.1 2.1 no signal
700 Jaundice 29 2.1 2.1 signal
701 Intestinal Haemorrhage 6 2.1 2.1 no signal
702 Haematocrit Decreased 21 2.1 2.1 signal
703 Hypercholesterolaemia 10 2.1 2.1 signal
704 Blood Alkaline Phosphatase Increased 26 2.1 2.1 signal
705 Melaena 23 2.1 2.1 signal
706 Pneumonitis 28 2.0 2.0 signal
707 Drug Intolerance 99 2.0 2.0 signal
708 Respiration Abnormal 7 2.0 2.0 no signal
709 Purpura 9 2.0 2.0 no signal
710 Coronary Artery Disease 31 2.0 2.0 signal
711 Blood Albumin Decreased 8 2.0 2.0 no signal
712 Respiratory Rate Increased 9 2.0 2.0 no signal
713 Hypomagnesaemia 14 2.0 2.0 no signal
714 Blister 56 2.0 2.0 no signal
715 Extrasystoles 7 2.0 2.0 no signal
716 Malnutrition 11 2.0 2.0 no signal
717 Pneumonia 319 1.9 2.0 no signal
718 Inappropriate Antidiuretic Hormone Secretion 10 1.9 1.9 no signal
719 Bronchospasm 14 1.9 1.9 no signal
720 Gastrointestinal Haemorrhage 82 1.9 1.9 no signal
721 Upper Respiratory Tract Infection 45 1.9 1.9 no signal
722 Respiratory Disorder 29 1.9 1.9 no signal
723 Hepatic Encephalopathy 9 1.9 1.9 no signal
724 C-reactive Protein Increased 35 1.9 1.9 no signal
725 Atrial Septal Defect 8 1.9 1.9 no signal
726 Lower Respiratory Tract Infection 43 1.9 1.9 no signal
727 Liver Disorder 42 1.9 1.9 no signal
728 Post Procedural Complication 18 1.8 1.8 no signal
729 Joint Injury 20 1.8 1.8 no signal
730 Herpes Simplex 6 1.8 1.8 no signal
731 Polyneuropathy 11 1.8 1.8 no signal
732 Cerebral Haemorrhage 33 1.8 1.8 no signal
733 Oxygen Saturation Decreased 51 1.8 1.8 no signal
734 Deafness Unilateral 5 1.8 1.8 no signal
735 Subdural Haematoma 13 1.8 1.8 no signal
736 Ischaemic Stroke 16 1.8 1.8 no signal
737 Gastric Ulcer 17 1.8 1.8 no signal
738 Myositis 8 1.8 1.8 no signal
739 Lung Infection 14 1.8 1.8 no signal
740 Abnormal Loss Of Weight 6 1.8 1.8 no signal
741 Rebound Effect 10 1.7 1.7 no signal
742 Drug Diversion 5 1.7 1.7 no signal
743 Platelet Count Decreased 93 1.7 1.7 no signal
744 Peripheral Coldness 12 1.7 1.7 no signal
745 Spinal Pain 10 1.7 1.7 no signal
746 Drug Eruption 15 1.7 1.7 no signal
747 Arteriosclerosis 8 1.7 1.7 no signal
748 Drug-induced Liver Injury 26 1.7 1.7 no signal
749 Colitis 31 1.6 1.6 no signal
750 Haemorrhage 86 1.6 1.6 no signal
751 Lethargy 47 1.6 1.6 no signal
752 Treatment Failure 67 1.6 1.6 no signal
753 Chronic Kidney Disease 62 1.6 1.6 no signal
754 Pancreatitis Acute 18 1.6 1.6 no signal
755 Lung Disorder 39 1.6 1.6 no signal
756 Neutrophil Count Decreased 32 1.6 1.6 no signal
757 Product Prescribing Issue 16 1.6 1.6 no signal
758 Gamma-glutamyltransferase Increased 17 1.5 1.5 no signal
759 Renal Injury 23 1.5 1.5 no signal
760 Haemoglobin Decreased 78 1.5 1.5 no signal
761 Cholecystitis 9 1.5 1.5 no signal
762 Erythema Multiforme 7 1.5 1.5 no signal
763 Drug Hypersensitivity 145 1.5 1.5 no signal
764 Pyrexia 258 1.5 1.5 no signal
765 Hypertension 157 1.5 1.5 no signal
766 Asphyxia 6 1.4 1.4 no signal
767 Therapy Partial Responder 11 1.4 1.4 no signal
768 Ecchymosis 5 1.4 1.4 no signal
769 Vomiting 339 1.4 1.4 no signal
770 Blood Pressure Abnormal 14 1.4 1.4 no signal
771 Pyelonephritis 6 1.4 1.4 no signal
772 Pallor 19 1.4 1.4 no signal
773 Tubulointerstitial Nephritis 13 1.4 1.4 no signal
774 Oral Candidiasis 9 1.4 1.4 no signal
775 Gastroenteritis 10 1.4 1.4 no signal
776 Liver Function Test Abnormal 20 1.3 1.3 no signal
777 Angioedema 30 1.3 1.3 no signal
778 Lymphocyte Count Decreased 12 1.3 1.3 no signal
779 Disease Progression 80 1.3 1.3 no signal
780 Haematemesis 17 1.3 1.3 no signal
781 Hepatic Enzyme Increased 45 1.3 1.3 no signal
782 Optic Neuritis 6 1.3 1.3 no signal
783 Small Intestinal Obstruction 8 1.3 1.3 no signal
784 White Blood Cell Count Increased 25 1.3 1.3 no signal
785 Apnoea 5 1.3 1.3 no signal
786 Neutropenia 86 1.3 1.3 no signal
787 Deep Vein Thrombosis 41 1.2 1.2 no signal
788 Obesity 10 1.2 1.2 no signal
789 Haematuria 21 1.2 1.2 no signal
790 Abnormal Faeces 5 1.2 1.2 no signal
791 Pancreatitis 32 1.2 1.2 no signal
792 Drug Withdrawal Syndrome Neonatal 9 1.2 1.2 no signal
793 Skin Disorder 20 1.2 1.2 no signal
794 Sars-cov-2 Test Positive 8 1.2 1.2 no signal
795 Oedema Peripheral 73 1.2 1.2 no signal
796 Contraindicated Product Administered 18 1.2 1.2 no signal
797 Ataxia 7 1.2 1.2 no signal
798 Cytopenia 7 1.2 1.2 no signal
799 Oedema 31 1.1 1.1 no signal
800 Fungal Infection 19 1.1 1.1 no signal
801 Incontinence 6 1.1 1.1 no signal
802 Oral Herpes 11 1.1 1.1 no signal
803 Transient Ischaemic Attack 19 1.1 1.1 no signal
804 Skin Discolouration 25 1.1 1.1 no signal
805 Diabetic Ketoacidosis 13 1.1 1.1 no signal
806 Respiratory Arrest 15 1.1 1.1 no signal
807 Cellulitis 27 1.1 1.1 no signal
808 Heart Rate Increased 53 1.1 1.1 no signal
809 Grand Mal Convulsion 5 1.1 1.1 no signal
810 Rash Erythematous 25 1.1 1.1 no signal
811 Device Failure 8 1.0 1.0 no signal
812 Epilepsy 16 1.0 1.0 no signal
813 Therapy Change 5 1.0 1.0 no signal
814 Gastric Haemorrhage 6 1.0 1.0 no signal
815 Thrombotic Microangiopathy 5 1.0 1.0 no signal
816 Loss Of Consciousness 66 1.0 1.0 no signal
817 Vasculitis 6 1.0 1.0 no signal
818 Acute Myeloid Leukaemia 8 1.0 1.0 no signal
819 Drug Effective For Unapproved Indication 15 1.0 1.0 no signal
820 Gingival Bleeding 7 1.0 1.0 no signal
821 Caesarean Section 6 1.0 1.0 no signal
822 Heart Rate Decreased 18 1.0 1.0 no signal
823 Hepatitis 13 1.0 1.0 no signal
824 Disease Recurrence 24 1.0 1.0 no signal
825 Blood Potassium Decreased 15 1.0 1.0 no signal
826 Bone Marrow Failure 10 1.0 1.0 no signal
827 Inflammation 25 1.0 1.0 no signal
828 Neutrophil Count Increased 5 1.0 1.0 no signal
829 Immunodeficiency 7 0.9 0.9 no signal
830 Hemiparesis 8 0.9 0.9 no signal
831 Hiatus Hernia 6 0.9 0.9 no signal
832 Platelet Count Increased 6 0.9 0.9 no signal
833 Intentional Product Use Issue 40 0.9 0.9 no signal
834 Complication Associated With Device 6 0.9 0.9 no signal
835 Device Related Infection 7 0.9 0.9 no signal
836 Cognitive Disorder 21 0.9 0.9 no signal
837 Blood Triglycerides Increased 8 0.9 0.9 no signal
838 Urinary Retention 15 0.9 0.9 no signal
839 Blood Calcium Decreased 5 0.9 0.9 no signal
840 Completed Suicide 37 0.9 0.9 no signal
841 Dyspnoea 248 0.9 0.9 no signal
842 Restlessness 16 0.9 0.9 no signal
843 Covid-19 77 0.9 0.9 no signal
844 Medication Error 24 0.9 0.9 no signal
845 Coordination Abnormal 6 0.8 0.8 no signal
846 Psychomotor Hyperactivity 7 0.8 0.8 no signal
847 Hyperthyroidism 6 0.8 0.8 no signal
848 Myelodysplastic Syndrome 6 0.8 0.8 no signal
849 Face Oedema 7 0.8 0.8 no signal
850 No Adverse Event 72 0.8 0.8 no signal
851 Rash Macular 14 0.8 0.8 no signal
852 Intestinal Obstruction 15 0.8 0.8 no signal
853 Aphasia 12 0.8 0.8 no signal
854 Musculoskeletal Stiffness 34 0.8 0.8 no signal
855 Folliculitis 4 0.8 0.8 no signal
856 Dermatitis 8 0.8 0.8 no signal
857 Nausea 304 0.8 0.8 no signal
858 Cardiac Failure Congestive 31 0.8 0.8 no signal
859 Death 322 0.7 0.7 no signal
860 Blood Sodium Decreased 7 0.7 0.7 no signal
861 Dysarthria 14 0.7 0.7 no signal
862 Wheezing 22 0.7 0.7 no signal
863 Confusional State 60 0.7 0.7 no signal
864 Gastrooesophageal Reflux Disease 29 0.7 0.7 no signal
865 Product Use Issue 67 0.7 0.7 no signal
866 Hyperhidrosis 46 0.7 0.7 no signal
867 Withdrawal Syndrome 15 0.7 0.7 no signal
868 Myelosuppression 12 0.7 0.7 no signal
869 Feeding Disorder 7 0.7 0.7 no signal
870 Syncope 35 0.7 0.7 no signal
871 Red Blood Cell Count Decreased 10 0.7 0.7 no signal
872 Mucosal Inflammation 9 0.7 0.7 no signal
873 Product Preparation Error 7 0.7 0.7 no signal
874 Product Prescribing Error 8 0.7 0.7 no signal
875 Interstitial Lung Disease 16 0.7 0.7 no signal
876 Haematotoxicity 3 0.6 0.6 no signal
877 No Therapeutic Response 4 0.6 0.6 no signal
878 Drug Abuse 27 0.6 0.6 no signal
879 Hepatic Steatosis 6 0.6 0.6 no signal
880 Leukaemia 3 0.6 0.6 no signal
881 Poisoning 4 0.6 0.6 no signal
882 Hypothyroidism 10 0.6 0.6 no signal
883 Abscess 5 0.6 0.6 no signal
884 Treatment Noncompliance 17 0.6 0.6 no signal
885 Asthma 35 0.6 0.6 no signal
886 Tremor 51 0.6 0.6 no signal
887 Peritonitis Bacterial 3 0.6 0.6 no signal
888 Dysphagia 28 0.6 0.6 no signal
889 Productive Cough 14 0.6 0.6 no signal
890 Blindness 12 0.6 0.6 no signal
891 Therapy Cessation 15 0.6 0.6 no signal
892 Infection 42 0.6 0.6 no signal
893 Coronary Artery Occlusion 4 0.6 0.6 no signal
894 Drug Toxicity 4 0.6 0.6 no signal
895 Mental Impairment 7 0.6 0.6 no signal
896 Urinary Tract Infection 49 0.6 0.6 no signal
897 Systemic Lupus Erythematosus 10 0.6 0.6 no signal
898 Therapeutic Response Decreased 17 0.6 0.6 no signal
899 Disorientation 11 0.5 0.5 no signal
900 Skin Exfoliation 23 0.5 0.5 no signal
901 Cholelithiasis 9 0.5 0.5 no signal
902 Sedation 7 0.5 0.5 no signal
903 Epistaxis 20 0.5 0.5 no signal
904 Chills 31 0.5 0.5 no signal
905 Muscle Twitching 6 0.5 0.5 no signal
906 Nightmare 9 0.5 0.5 no signal
907 Emotional Disorder 8 0.5 0.5 no signal
908 Infusion Related Reaction 17 0.5 0.5 no signal
909 Swollen Tongue 8 0.5 0.5 no signal
910 Therapeutic Product Effect Incomplete 18 0.5 0.5 no signal
911 Haematochezia 14 0.5 0.5 no signal
912 Mental Disorder 11 0.5 0.5 no signal
913 Extra Dose Administered 10 0.5 0.5 no signal
914 Amenorrhoea 4 0.5 0.5 no signal
915 Aggression 12 0.5 0.5 no signal
916 Erythema 49 0.5 0.5 no signal
917 Muscular Weakness 27 0.5 0.5 no signal
918 Tuberculosis 3 0.5 0.5 no signal
919 Respiratory Tract Infection 6 0.5 0.5 no signal
920 Faeces Discoloured 5 0.5 0.5 no signal
921 Product Dispensing Error 5 0.5 0.5 no signal
922 Anorexia 3 0.5 0.5 no signal
923 Gastrointestinal Disorder 20 0.4 0.4 no signal
924 Asthenia 85 0.4 0.4 no signal
925 Therapeutic Product Effect Decreased 10 0.4 0.4 no signal
926 Drug Administration Error 7 0.4 0.4 no signal
927 Skin Lesion 6 0.4 0.4 no signal
928 Akathisia 3 0.4 0.4 no signal
929 Dehydration 29 0.4 0.4 no signal
930 Renal Disorder 10 0.4 0.4 no signal
931 Dyspnoea Exertional 8 0.4 0.4 no signal
932 White Blood Cell Count Decreased 23 0.4 0.4 no signal
933 Pain In Jaw 6 0.4 0.4 no signal
934 Rash 90 0.4 0.4 no signal
935 Cerebrovascular Accident 35 0.4 0.4 no signal
936 Underdose 15 0.4 0.4 no signal
937 Accidental Exposure To Product 20 0.4 0.4 no signal
938 Hallucination 15 0.4 0.4 no signal
939 Cough 55 0.4 0.4 no signal
940 Incorrect Dose Administered 42 0.4 0.4 no signal
941 Rectal Haemorrhage 8 0.4 0.4 no signal
942 Disturbance In Attention 10 0.4 0.4 no signal
943 Drug Withdrawal Syndrome 16 0.4 0.4 no signal
944 Visual Acuity Reduced 6 0.4 0.4 no signal
945 Hypersensitivity 33 0.4 0.3 no signal
946 Chest Pain 33 0.4 0.3 no signal
947 Diarrhoea 114 0.3 0.3 no signal
948 Fluid Retention 9 0.3 0.3 no signal
949 Myocardial Infarction 31 0.3 0.3 no signal
950 Convulsion 10 0.3 0.3 no signal
951 Urticaria 27 0.3 0.3 no signal
952 Eczema 8 0.3 0.3 no signal
953 Inappropriate Schedule Of Product Administration 28 0.3 0.3 no signal
954 Malignant Neoplasm Progression 16 0.3 0.3 no signal
955 Cystitis 5 0.3 0.3 no signal
956 Therapeutic Response Unexpected 7 0.3 0.3 no signal
957 Expired Product Administered 5 0.3 0.3 no signal
958 Stomatitis 9 0.3 0.3 no signal
959 Suicidal Ideation 13 0.3 0.3 no signal
960 Myalgia 24 0.3 0.3 no signal
961 Tardive Dyskinesia 4 0.3 0.3 no signal
962 Abdominal Pain Upper 28 0.3 0.3 no signal
963 Device Malfunction 9 0.3 0.3 no signal
964 Nephrolithiasis 6 0.3 0.3 no signal
965 Therapy Interrupted 9 0.3 0.3 no signal
966 Dyskinesia 5 0.2 0.2 no signal
967 Amnesia 8 0.2 0.2 no signal
968 Drug Dose Omission By Device 9 0.2 0.2 no signal
969 Cardiac Disorder 11 0.2 0.2 no signal
970 Device Delivery System Issue 3 0.2 0.2 no signal
971 Speech Disorder 6 0.2 0.2 no signal
972 Depressed Mood 6 0.2 0.2 no signal
973 Decreased Appetite 26 0.2 0.2 no signal
974 Incorrect Route Of Drug Administration 4 0.2 0.2 no signal
975 Wrong Technique In Device Usage Process 5 0.2 0.2 no signal
976 Malaise 48 0.2 0.2 no signal
977 Chest Discomfort 11 0.2 0.2 no signal
978 Flushing 11 0.2 0.2 no signal
979 Surgery 6 0.2 0.2 no signal
980 Irritability 6 0.2 0.2 no signal
981 Discomfort 6 0.2 0.2 no signal
982 Dizziness 49 0.2 0.2 no signal
983 Fall 32 0.2 0.2 no signal
984 Pain 59 0.2 0.2 no signal
985 Fatigue 74 0.2 0.2 no signal
986 Neuropathy Peripheral 9 0.2 0.2 no signal
987 Anxiety 27 0.2 0.2 no signal
988 Palpitations 11 0.2 0.2 no signal
989 Drug Effect Decreased 5 0.2 0.2 no signal
990 Blood Pressure Increased 14 0.2 0.2 no signal
991 Visual Impairment 11 0.2 0.2 no signal
992 Muscle Spasms 16 0.2 0.2 no signal
993 Pruritus 32 0.2 0.2 no signal
994 Headache 53 0.2 0.2 no signal
995 Mobility Decreased 6 0.2 0.2 no signal
996 Paraesthesia 13 0.2 0.2 no signal
997 Product Quality Issue 11 0.2 0.2 no signal
998 Product Dose Omission Issue 23 0.2 0.2 no signal
999 Blood Glucose Increased 15 0.2 0.2 no signal
1000 Peripheral Swelling 12 0.2 0.2 no signal
1001 Contusion 7 0.1 0.1 no signal
1002 Abdominal Discomfort 12 0.1 0.1 no signal
1003 Device Issue 6 0.1 0.1 no signal
1004 Insomnia 17 0.1 0.1 no signal
1005 Influenza 7 0.1 0.1 no signal
1006 Adverse Event 5 0.1 0.1 no signal
1007 Dependence 3 0.1 0.1 no signal
1008 Arthralgia 22 0.1 0.1 no signal
1009 Dyspepsia 5 0.1 0.1 no signal
1010 Weight Decreased 14 0.1 0.1 no signal
1011 Drug Dependence 8 0.1 0.1 no signal
1012 Back Pain 11 0.1 0.1 no signal
1013 Pain In Extremity 13 0.1 0.1 no signal
1014 Gait Disturbance 8 0.1 0.1 no signal
1015 Weight Increased 9 0.1 0.1 no signal
1016 Depression 9 0.1 0.1 no signal
1017 Hospitalisation 6 0.1 0.1 no signal
1018 Wrong Technique In Product Usage Process 7 0.1 0.1 no signal
1019 Nasopharyngitis 6 0.1 0.1 no signal
1020 Alopecia 6 0.1 0.1 no signal