Reaction

Systolic Dysfunction reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,040 reports · 38 co-occurring drugs

As of the last recalculation, Systolic Dysfunction appears in 1,040 FAERS reports alongside 38 co-occurring drug terms. The strongest observed disproportionality signal is NOREPINEPHRINE (PRR 61.8).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Norepinephrine	32	61.8	62.0
Norepinephrine Bitartrate	32	45.9	46.0
Ciclesonide	27	40.7	40.8
Atropine	15	36.7	36.8
Atropine Sulfate	17	32.0	32.0
Phenobarbital	20	28.1	28.2
Esomeprazole Magnesium Capsule, Delayed Release	19	26.7	26.7
Esomeprazole Magnesium Delayed Release Capsules	19	26.7	26.7
Esomeprazole Magnesium Dihydrate	19	26.6	26.6
Telmisartan	22	25.2	25.2
Linagliptin	22	24.6	24.7
Clobazam	27	22.7	22.7
Esomeprazole	59	20.1	20.1
Polyethylene Glycol	10	18.7	18.7
Tranexamic Acid	8	18.1	18.1
Selexipag	22	17.4	17.4
Bisoprolol Fumarate	104	16.9	16.9
Midazolam Hydrochloride	22	16.7	16.7
Pertuzumab	22	16.5	16.5
Ramipril	90	15.8	15.8
Doxorubicin Hydrochloride	25	15.7	15.7
Trastuzumab	51	15.6	15.6
Epoprostenol	10	15.4	15.4
Clopidogrel Bisulfate	73	15.3	15.3
Doxorubicin	57	13.5	13.5
Aripiprazole Oral	27	13.4	13.4
Aripiprazole Orally Disintegrating	27	13.4	13.4
Propofol	23	12.9	12.9
Eplerenone	8	12.6	12.6
Tafamidis	7	12.0	12.0
Sacubitril And Valsartan	64	11.7	11.7
Agalsidase Beta	5	10.9	10.9
Clozapine	60	10.1	10.1
Amphetamine	4	9.7	9.7
Docetaxel Anhydrous	31	9.5	9.5
Docetaxel	31	9.5	9.5
Paliperidone	10	8.7	8.7
Carfilzomib	12	8.6	8.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.