OpenPV Signal Explorer
FAERS disproportionality dashboard
Reaction

Distributive Shock reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,181 reports · 95 co-occurring drugs

As of the last recalculation, Distributive Shock appears in 2,181 FAERS reports alongside 95 co-occurring drug terms. The strongest observed disproportionality signal is NOREPINEPHRINE (PRR 76.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Norepinephrine8276.076.6
Norepinephrine Bitartrate10069.469.9
Amlodipine75640.440.5
Basiliximab3428.028.1
Methocarbamol Tablets4325.025.0
Pyrazinamide2424.624.7
Guanfacine2024.524.5
Cariprazine2323.823.9
Calcium Gluconate2520.020.1
Rifampin2818.518.6
Bupropion8318.418.5
Methocarbamol4318.418.5
Adrenalinum7718.318.4
Mycophenilic Acid3817.817.8
Hydroxyzine8116.816.8
Metformin Hydrochloride Tablets9115.815.8
Metformin Hydrochloride Extended-Release Tablets9115.815.8
Metformin Hydrochloride Tablet9115.815.8
Metformin Hydrochloride9315.615.6
Isoniazid2414.314.3
Terazosin Hydrochloride1314.014.0
Cyclobenzaprine7114.014.0
Brexpiprazole2313.413.4
Hydroxyzine Hydrochloride1712.412.4
Hydroxyzine Hydrochloride Oral1712.412.4
Epinephrine7811.811.8
Mycophenolic Acid3811.511.5
Felodipine Extended-Release Tablets1311.011.0
Felodipine1311.011.0
Magnesium Oxide4410.210.2
Cefepime Hydrochloride1710.110.2
Cefepime1510.010.1
Amlodipine Besylate1439.99.9
Ziprasidone189.89.8
Lamotirigine719.79.8
Lamotrigine Extended-Release719.79.8
Lamotrigine Chewable Dispersible719.79.8
Cyclobenzaprine Hydrochloride99.69.6
Metformin3059.39.3
Clonidine499.39.3
Ethyl Alcohol258.98.9
Oxazepam198.58.5
Febuxostat Tablets 40 Mg98.58.5
Febuxostat Tablets 80 Mg98.58.5
Valsartan Oral478.48.4
Sodium Bicarbonate208.38.3
Sodium Bicarbonate Injection,208.38.3
Piperacillin And Tazobactam118.28.2
Midazolam Hydrochloride238.28.2
Carisoprodol168.18.1
Midazolam218.08.0
Dextrose118.08.0
Dextrose Monohydrate117.97.9
Venlafaxine577.87.8
Fluoxetine537.77.8
Diltiazem Hydrochloride Extended-Release Tablets97.67.6
Propranolol Hydrochloride557.47.4
Metformin Er 500 Mg2147.47.4
Metformin Er 750 Mg2147.47.4
Rocuronium Bromide97.37.3
Methimazole67.37.3
Colchicine207.37.3
Vancomycin437.27.2
Meropenem247.27.2
Isopropyl Alcohol257.17.1
Metronidazole Topical357.17.1
Fenofibrate267.17.1
Tamsulosin Hydrochloride157.17.1
Sevoflurane66.96.9
Piperacillin Sodium,Tazobactam Sodium196.96.9
Linezolid216.86.8
Aripiprazole Oral296.86.8
Aripiprazole Orally Disintegrating296.86.8
Vancomycin Hydrochloride446.56.5
Linagliptin126.36.3
Alcohol256.26.2
Lisinopril1816.16.1
Tacrolimus Ointment 0.1%745.85.8
Tacrolimus Extended-Release Capsules745.85.8
Micafungin Sodium55.65.6
Propofol215.55.5
Febuxostat95.15.1
Bupivacaine55.15.1
Pegaspargase64.74.7
Atazanavir74.74.7
Amphetamine44.64.6
Icosapent Ethyl44.54.5
Vemurafenib54.04.0
Axicabtagene Ciloleucel43.93.9
Temozolomide83.63.6
Daptomycin33.13.1
Minoxidil Foam 5% (Womens)92.62.6
Exenatide132.42.4
Minoxidil91.91.9
Nirmatrelvir And Ritonavir81.41.4

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Data source: openFDA FAERS. See the OpenPV methodology and limitations.