Reaction

Hyperlactacidaemia reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,604 reports · 113 co-occurring drugs

As of the last recalculation, Hyperlactacidaemia appears in 2,604 FAERS reports alongside 113 co-occurring drug terms. The strongest observed disproportionality signal is NOREPINEPHRINE (PRR 74.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Norepinephrine	96	74.5	75.2
Zidovudine	111	69.3	69.8
Norepinephrine Bitartrate	115	66.8	67.3
Linezolid	166	47.5	47.8
Nevirapine	49	44.2	44.5
Lamivudine	141	38.5	38.7
Lopinavir And Ritonavir	62	37.4	37.6
Abacavir Sulfate	40	33.3	33.5
Lamivudine Oral	92	30.1	30.2
Efavirenz	38	27.6	27.7
Metformin	804	25.6	25.7
Metformin Hydrochloride Tablet	172	25.6	25.7
Metformin Hydrochloride Tablets	171	25.4	25.5
Metformin Hydrochloride Extended-Release Tablets	171	25.4	25.5
Metformin Hydrochloride	173	25.0	25.0
Dextrose Monohydrate	38	23.0	23.1
Dextrose	37	22.8	22.8
Metformin Er 500 Mg	633	21.9	21.9
Metformin Er 750 Mg	633	21.9	21.9
Amikacin	42	20.0	20.0
Ritonavir	68	19.1	19.1
Linagliptin	42	18.7	18.7
Ganciclovir Sodium	24	18.3	18.3
Ganciclovir	23	18.1	18.2
Meropenem	70	17.9	17.9
Acetylcysteine	17	14.5	14.5
Sitagliptin And Metformin Hydrochloride	35	13.1	13.2
Adrenalinum	66	13.0	13.0
Ritonavir 100 Mg	24	13.0	13.0
Piperacillin And Tazobactam	20	12.6	12.6
Propofol	55	12.3	12.3
Felodipine Extended-Release Tablets	17	12.0	12.0
Felodipine	17	12.0	12.0
Raltegravir	24	11.7	11.7
Ceftriaxone	47	11.6	11.7
Phytonadione	12	11.4	11.4
Magnesium Sulfate In Water For	18	11.3	11.4
Heparin Sodium	19	11.1	11.1
Magnesium Sulfate Heptahydrate	18	11.1	11.1
Magnesium Sulfate	18	11.1	11.1
Valproic Acid	42	10.8	10.8
Piperacillin Sodium,Tazobactam Sodium	35	10.7	10.7
Cefuroxime	15	10.5	10.6
Ceftriaxone Sodium	48	10.2	10.2
Valproate Sodium	25	9.8	9.8
Voriconazole Injection	26	9.7	9.7
Nebivolol	19	9.6	9.6
Indapamide	20	9.0	9.0
Candesartan	39	8.9	8.9
Haloperidol Lactate	27	8.8	8.8
Irbesartan	48	8.7	8.7
Ampicillin	9	8.7	8.7
Ampicillin Sodium	9	8.7	8.7
Daptomycin	10	8.7	8.7
Sevoflurane	9	8.7	8.7
Haloperidol	26	8.6	8.6
Epinephrine	68	8.5	8.5
Oxazepam	22	8.2	8.2
Piperacillin Sodium And Tazobactam Sodium	20	8.2	8.2
Candesartan Cilexetil	26	8.0	8.0
Sodium Bicarbonate	23	8.0	8.0
Sodium Bicarbonate Injection,	23	8.0	8.0
Anti-Thymocyte Globulin (Rabbit)	8	7.9	8.0
Dapagliflozin	29	7.4	7.4
Insulin Glargine-Yfgn	20	7.4	7.4
Atazanavir	13	7.3	7.3
Midazolam Hydrochloride	24	7.2	7.2
Moxifloxacin Hydrochloride	18	7.1	7.1
Tenofovir Disoproxil Fumarate	29	7.1	7.1
Oseltamivir	7	7.0	7.0
Voriconazole	26	6.9	6.9
Rocuronium Bromide	10	6.8	6.8
Telmisartan	15	6.8	6.8
Desloratadine	9	6.7	6.7
Divalproex Sodium	38	6.6	6.6
Ethyl Alcohol	22	6.5	6.5
Sulfamethoxazole And Trimethoprim	67	6.5	6.5
Sitagliptin	57	6.4	6.4
Rifampicin	8	6.3	6.3
Fluoxetine	51	6.2	6.2
Colchicine	20	6.1	6.1
Ramipril	89	5.9	5.9
Gemfibrozil	11	5.8	5.8
Amphotericin B	9	5.8	5.8
Midazolam	18	5.7	5.7
Gentamicin	9	5.5	5.5
Entecavir	8	5.5	5.5
Isopropyl Alcohol	23	5.5	5.5
Agalsidase Beta	6	5.2	5.2
Posaconazole Delayed-Release	7	5.1	5.1
Iron Sucrose	6	5.0	5.0
Isosorbide Mononitrate	13	5.0	5.0
Eplerenone	8	5.0	5.0
Iohexol	5	4.8	4.8
Alcohol	23	4.8	4.8
Risperidone	77	4.7	4.7
Febuxostat Tablets 40 Mg	6	4.7	4.7
Febuxostat Tablets 80 Mg	6	4.7	4.7
Brentuximab Vedotin	6	4.7	4.7
Fosaprepitant Dimeglumine	8	4.7	4.7
Oseltamivir Phosphate	14	4.6	4.6
Nebivolol Hydrochloride	19	4.5	4.5
Rifampin	8	4.4	4.4
Metformin Hcl	30	4.4	4.4
Pyrazinamide	5	4.3	4.3
Darunavir	8	4.2	4.2
Empagliflozin	32	3.8	3.8
Tenofovir Disoproxil Fumarate Tablets	4	3.7	3.7
Bendamustine Hydrochloride	5	3.3	3.3
Emtricitabine And Tenofovir Disoproxil Fumarate	14	2.5	2.5
Obinutuzumab	5	2.4	2.4
Encorafenib	3	2.4	2.4
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate	4	1.8	1.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.