OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Regorafenib

1,009 flagged reaction(s) · 52,630 total co-reports · max PRR 995.5
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Gastrointestinal Stromal Cancer 15 995.5 996.7 signal
2 Clear Cell Sarcoma Of Soft Tissue 5 559.9 560.2 signal
3 Dedifferentiated Liposarcoma 6 336.0 336.1 signal
4 Colorectal Cancer Metastatic 320 295.9 304.3 signal
5 Osteosarcoma Recurrent 8 275.7 275.9 signal
6 Metastases To Biliary Tract 5 242.1 242.2 signal
7 Oral Hyperaesthesia 5 235.8 235.9 signal
8 Thermohyperaesthesia 5 235.8 235.9 signal
9 Osteosarcoma Metastatic 11 234.6 234.9 signal
10 Protein Induced By Vitamin K Absence Or Antagonist Ii Increased 8 224.0 224.1 signal
11 Colorectal Cancer Recurrent 13 204.3 204.6 signal
12 Plantar Erythema 24 196.4 196.8 signal
13 Tumour Cavitation 5 182.8 182.9 signal
14 Rectal Cancer Stage Iv 5 175.7 175.7 signal
15 Metastases To Salivary Gland 5 169.0 169.1 signal
16 Alpha 1 Foetoprotein Increased 51 139.7 140.3 signal
17 Rectal Cancer Recurrent 6 139.6 139.7 signal
18 Colon Cancer Recurrent 19 135.6 135.9 signal
19 Hepatocellular Carcinoma 487 123.9 129.3 signal
20 Rectal Cancer Metastatic 22 123.2 123.4 signal
21 Palmar-plantar Erythrodysaesthesia Syndrome 1,439 119.1 136.0 signal
22 Gastrointestinal Stromal Tumour 142 101.7 102.9 signal
23 Carcinoembryonic Antigen Increased 101 100.3 101.1 signal
24 Colon Cancer Metastatic 78 92.7 93.4 signal
25 Rectosigmoid Cancer 9 76.4 76.5 signal
26 Palmoplantar Keratoderma 27 70.7 70.9 signal
27 Food Refusal 31 69.3 69.4 signal
28 Tumour Embolism 6 60.4 60.4 signal
29 Rectal Cancer 98 59.7 60.2 signal
30 Tumour Compression 10 58.9 59.0 signal
31 Metastases To Lung 329 53.3 54.8 signal
32 Metastases To Abdominal Cavity 14 52.9 53.0 signal
33 Tumour Marker Decreased 5 51.5 51.5 signal
34 Hyperkeratosis 149 50.3 50.9 signal
35 Rectal Adenocarcinoma 16 49.9 50.0 signal
36 Metastases To Abdominal Wall 5 48.4 48.4 signal
37 Tumour Perforation 8 47.9 48.0 signal
38 Tumour Ulceration 6 47.6 47.6 signal
39 Tumour Rupture 14 47.2 47.2 signal
40 Carbohydrate Antigen 19-9 Increased 13 46.7 46.7 signal
41 Hepatic Cancer Recurrent 7 45.8 45.8 signal
42 Metastases To Adrenals 22 44.5 44.6 signal
43 Colon Cancer 344 42.8 44.1 signal
44 Intestinal Metastasis 8 42.3 42.3 signal
45 Metastases To Pelvis 14 41.2 41.2 signal
46 Metastases To Peritoneum 54 40.0 40.2 signal
47 Retroperitoneal Lymphadenopathy 11 38.7 38.8 signal
48 Osteosarcoma 8 38.5 38.6 signal
49 Infected Neoplasm 5 37.6 37.7 signal
50 Tumour Associated Fever 8 37.0 37.1 signal
51 Liver Carcinoma Ruptured 5 36.7 36.7 signal
52 Scrotal Ulcer 5 35.0 35.0 signal
53 Pulmonary Cavitation 16 34.3 34.3 signal
54 Nephrostomy 6 33.9 33.9 signal
55 Angular Cheilitis 12 32.4 32.4 signal
56 Coma Hepatic 13 32.0 32.1 signal
57 Metastases To Liver 282 29.7 30.4 signal
58 Tumour Marker Increased 77 29.5 29.7 signal
59 Metastases To Ovary 5 29.1 29.1 signal
60 Adenocarcinoma Of Colon 29 28.5 28.6 signal
61 Intra-abdominal Fluid Collection 27 28.1 28.2 signal
62 Acoustic Neuroma 6 27.2 27.2 signal
63 Metastases To The Mediastinum 6 26.6 26.6 signal
64 Dysphonia 821 25.9 27.8 signal
65 Tumour Pain 18 25.0 25.1 signal
66 Colon Cancer Stage Iv 8 24.6 24.6 signal
67 Hepatic Atrophy 6 24.5 24.6 signal
68 Mediastinal Mass 5 24.3 24.4 signal
69 Cancer Pain 32 22.9 23.0 signal
70 Tumour Necrosis 13 22.7 22.8 signal
71 Palmar Erythema 14 22.4 22.5 signal
72 Metastases To Lymph Nodes 77 21.1 21.2 signal
73 Systolic Hypertension 5 20.9 20.9 signal
74 Exercise Tolerance Decreased 64 20.6 20.7 signal
75 Skin Induration 23 20.5 20.5 signal
76 Post-traumatic Pain 5 20.0 20.0 signal
77 Traumatic Fracture 8 19.9 19.9 signal
78 Malignant Ascites 8 19.1 19.2 signal
79 Bile Duct Obstruction 20 19.1 19.1 signal
80 Skin Toxicity 57 18.7 18.8 signal
81 Hepatic Encephalopathy 93 18.3 18.4 signal
82 Blood Bilirubin Increased 266 18.0 18.4 signal
83 Abdominal Lymphadenopathy 8 17.1 17.1 signal
84 Hepatic Pain 39 16.7 16.8 signal
85 Ocular Icterus 39 16.5 16.6 signal
86 Blister Infected 7 16.3 16.3 signal
87 Malignant Peritoneal Neoplasm 5 15.4 15.4 signal
88 Lymphadenopathy Mediastinal 16 15.4 15.4 signal
89 Ammonia Increased 42 15.1 15.1 signal
90 Blister 455 14.9 15.4 signal
91 Eastern Cooperative Oncology Group Performance Status Worsened 10 14.7 14.7 signal
92 Gastrointestinal Perforation 33 14.5 14.6 signal
93 Stoma Site Haemorrhage 12 14.4 14.4 signal
94 Oral Pain 173 14.1 14.3 signal
95 Impaired Self-care 16 13.9 13.9 signal
96 Perforation 6 13.8 13.8 signal
97 Aphagia 36 13.5 13.5 signal
98 Gastrointestinal Oedema 13 13.5 13.5 signal
99 Ascites 212 13.2 13.4 signal
100 Biliary Obstruction 9 13.2 13.2 signal
101 Tumour Haemorrhage 20 12.8 12.8 signal
102 Hyperammonaemic Encephalopathy 12 12.8 12.8 signal
103 Female Genital Tract Fistula 12 12.7 12.8 signal
104 Hepatic Cancer Metastatic 6 12.7 12.7 signal
105 Change Of Bowel Habit 14 12.5 12.5 signal
106 Blister Rupture 5 12.4 12.4 signal
107 Skin Hypertrophy 19 12.4 12.4 signal
108 Therapeutic Product Ineffective 26 12.1 12.1 signal
109 Skin Wound 11 12.1 12.1 signal
110 Tongue Ulceration 22 11.9 11.9 signal
111 Hepatic Lesion 28 11.8 11.9 signal
112 Hyperbilirubinaemia 66 11.7 11.8 signal
113 Appendix Cancer 6 11.7 11.7 signal
114 Intestinal Fistula 9 11.7 11.7 signal
115 Duodenal Perforation 6 11.3 11.3 signal
116 Skin Fissures 116 11.2 11.3 signal
117 Anal Ulcer 5 11.2 11.2 signal
118 Administration Site Extravasation 6 11.1 11.1 signal
119 Fluid Intake Reduced 30 11.1 11.1 signal
120 Protein Urine Present 30 11.0 11.1 signal
121 Gene Mutation 12 11.0 11.0 signal
122 Mucosal Inflammation 157 11.0 11.1 signal
123 Pharyngeal Ulceration 8 11.0 11.0 signal
124 Oesophageal Varices Haemorrhage 13 10.9 10.9 signal
125 Hypoproteinaemia 11 10.9 10.9 signal
126 Colorectal Cancer 286 10.8 11.1 signal
127 Metastases To Pleura 6 10.5 10.5 signal
128 Prerenal Failure 8 10.5 10.5 signal
129 Hepatic Mass 11 10.5 10.5 signal
130 Metastasis 41 10.4 10.5 signal
131 Gastrointestinal Fistula 5 10.4 10.4 signal
132 Stomatitis 342 10.3 10.6 signal
133 Jaundice 150 10.1 10.3 signal
134 Metastases To Central Nervous System 69 9.8 9.9 signal
135 Neuropathy Peripheral 504 9.7 10.1 signal
136 Aspartate Aminotransferase Abnormal 8 9.7 9.7 signal
137 Proctalgia 34 9.7 9.7 signal
138 Subileus 11 9.6 9.6 signal
139 Early Satiety 10 9.6 9.6 signal
140 Pre-existing Condition Improved 32 9.3 9.3 signal
141 Feeding Disorder 101 9.2 9.3 signal
142 Hepatic Function Abnormal 187 9.2 9.3 signal
143 Mucous Membrane Disorder 7 9.2 9.2 signal
144 Cell Death 10 9.2 9.2 signal
145 Bone Marrow Toxicity 6 9.1 9.1 signal
146 Proteinuria 94 9.1 9.2 signal
147 Performance Status Decreased 23 9.0 9.0 signal
148 Tongue Blistering 11 9.0 9.0 signal
149 Xerosis 6 8.9 8.9 signal
150 Glioblastoma 8 8.7 8.7 signal
151 Glossitis 17 8.7 8.7 signal
152 Biliary Dilatation 7 8.7 8.7 signal
153 Bilirubin Conjugated Increased 11 8.6 8.6 signal
154 Blood Bilirubin Abnormal 6 8.6 8.6 signal
155 Decreased Appetite 1,091 8.6 9.4 signal
156 Yellow Skin 22 8.6 8.6 signal
157 Oral Mucosal Blistering 30 8.6 8.6 signal
158 Disseminated Intravascular Coagulation 66 8.5 8.6 signal
159 Suspected Off Label Use 8 8.4 8.4 signal
160 Hypogeusia 9 8.4 8.4 signal
161 Abnormal Loss Of Weight 31 8.4 8.4 signal
162 Nephrotic Syndrome 31 8.3 8.3 signal
163 Metastases To Spine 15 8.2 8.2 signal
164 Hepatic Failure 133 8.0 8.1 signal
165 Physical Deconditioning 11 8.0 8.0 signal
166 Aphonia 61 8.0 8.0 signal
167 Pneumoperitoneum 8 8.0 8.0 signal
168 Gastrointestinal Motility Disorder 23 7.9 7.9 signal
169 Skin Exfoliation 359 7.9 8.1 signal
170 Hypoalbuminaemia 33 7.9 7.9 signal
171 Hepatic Neoplasm 14 7.8 7.8 signal
172 Medical Procedure 7 7.8 7.8 signal
173 Jaundice Cholestatic 15 7.7 7.7 signal
174 Hyperaesthesia 35 7.7 7.7 signal
175 Gait Inability 140 7.7 7.8 signal
176 Hyperammonaemia 21 7.7 7.7 signal
177 Decreased Activity 45 7.7 7.7 signal
178 Paronychia 18 7.6 7.6 signal
179 Myelosuppression 141 7.6 7.6 signal
180 Metastases To Bone 67 7.5 7.5 signal
181 Immune-mediated Hepatitis 8 7.4 7.4 signal
182 Blood Magnesium Decreased 35 7.4 7.4 signal
183 Tongue Discomfort 17 7.4 7.4 signal
184 Dyschezia 12 7.2 7.3 signal
185 Dermatitis Acneiform 24 7.2 7.2 signal
186 Cholangitis 24 7.1 7.1 signal
187 Abdominal Tenderness 19 7.0 7.0 signal
188 Therapy Partial Responder 57 6.9 6.9 signal
189 Hepatitis Fulminant 11 6.7 6.8 signal
190 Oropharyngeal Blistering 6 6.6 6.6 signal
191 Colostomy 7 6.5 6.5 signal
192 N-terminal Prohormone Brain Natriuretic Peptide Increased 5 6.5 6.5 signal
193 Congestive Cardiomyopathy 15 6.5 6.5 signal
194 Auditory Disorder 5 6.5 6.5 signal
195 Intestinal Haemorrhage 20 6.5 6.5 signal
196 Blood Electrolytes Decreased 5 6.4 6.4 signal
197 Genital Rash 5 6.4 6.4 signal
198 Product Prescribing Issue 70 6.3 6.3 signal
199 Dehydration 458 6.3 6.5 signal
200 Blood Albumin Decreased 27 6.2 6.2 signal
201 Coccydynia 5 6.2 6.2 signal
202 Hypophosphataemia 25 6.2 6.2 signal
203 Pain Of Skin 91 6.1 6.2 signal
204 Chromaturia 76 6.1 6.2 signal
205 Emergency Care 10 6.1 6.1 signal
206 Thyroiditis 10 6.1 6.1 signal
207 Bedridden 44 6.1 6.1 signal
208 Haematotoxicity 31 6.1 6.1 signal
209 Alanine Aminotransferase Abnormal 7 6.1 6.1 signal
210 Rash Vesicular 16 6.1 6.1 signal
211 Cachexia 17 6.0 6.1 signal
212 Urinary Bladder Haemorrhage 7 6.0 6.0 signal
213 Hypertension 695 6.0 6.3 signal
214 Rash Generalised 86 6.0 6.0 signal
215 Immune-mediated Myocarditis 5 5.9 5.9 signal
216 Oral Mucosal Erythema 5 5.9 5.9 signal
217 Aspartate Aminotransferase Increased 171 5.9 5.9 signal
218 Gastrointestinal Toxicity 15 5.8 5.8 signal
219 Blood Loss Anaemia 7 5.7 5.7 signal
220 Fibrin D Dimer Increased 11 5.6 5.6 signal
221 Odynophagia 18 5.5 5.6 signal
222 Lung Neoplasm 13 5.5 5.5 signal
223 Abdominal Mass 8 5.4 5.5 signal
224 Terminal State 20 5.4 5.4 signal
225 Blood Pressure Increased 456 5.4 5.6 signal
226 Malignant Pleural Effusion 5 5.4 5.4 signal
227 Abdominal Rigidity 8 5.4 5.4 signal
228 Skin Warm 17 5.3 5.3 signal
229 Glossodynia 65 5.3 5.3 signal
230 Lipase Increased 22 5.3 5.3 signal
231 Large Intestine Perforation 20 5.2 5.2 signal
232 Abasia 72 5.2 5.3 signal
233 Necrotising Fasciitis 10 5.2 5.2 signal
234 Posterior Reversible Encephalopathy Syndrome 27 5.2 5.2 signal
235 Pulmonary Mass 42 5.1 5.2 signal
236 Anal Fistula 15 5.1 5.1 signal
237 Anorectal Discomfort 15 5.1 5.1 signal
238 Hepatotoxicity 62 5.1 5.1 signal
239 Lip Pain 8 5.1 5.1 signal
240 Appetite Disorder 18 5.0 5.0 signal
241 Ileus 34 5.0 5.0 signal
242 Dyspnoea At Rest 8 5.0 5.0 signal
243 Haemorrhage Urinary Tract 7 5.0 5.0 signal
244 Skin Ulcer 71 5.0 5.0 signal
245 Abdominal Abscess 12 4.9 5.0 signal
246 Blood Alkaline Phosphatase Increased 67 4.9 4.9 signal
247 Hypophagia 68 4.9 4.9 signal
248 Hydronephrosis 20 4.9 4.9 signal
249 Exfoliative Rash 7 4.9 4.9 signal
250 Eating Disorder 57 4.9 4.9 signal
251 Hepatitis Toxic 7 4.9 4.9 signal
252 Gingival Pain 21 4.8 4.8 signal
253 Pain In Extremity 774 4.8 5.0 signal
254 Dermatitis Exfoliative Generalised 9 4.8 4.8 signal
255 Immune-mediated Hepatic Disorder 5 4.8 4.8 signal
256 Portal Hypertension 8 4.7 4.7 signal
257 Liver Disorder 114 4.7 4.7 signal
258 Gastric Perforation 7 4.7 4.7 signal
259 Disease Progression 300 4.6 4.7 signal
260 Urinary Tract Obstruction 6 4.6 4.6 signal
261 Hepatitis B Reactivation 8 4.6 4.6 signal
262 Asthenia 946 4.6 4.9 signal
263 Platelet Count Decreased 267 4.6 4.6 signal
264 Skin Erosion 8 4.6 4.6 signal
265 Anal Haemorrhage 7 4.5 4.5 signal
266 Intestinal Perforation 28 4.5 4.5 signal
267 Sensitive Skin 18 4.5 4.5 signal
268 Erythema Multiforme 23 4.5 4.5 signal
269 Hypersomnia 70 4.5 4.5 signal
270 Chest Injury 5 4.4 4.4 signal
271 Cholecystitis 29 4.4 4.5 signal
272 Rectal Discharge 9 4.4 4.4 signal
273 Anal Abscess 13 4.4 4.4 signal
274 Hypothyroidism 77 4.4 4.4 signal
275 Skin Reaction 34 4.4 4.4 signal
276 Alanine Aminotransferase Increased 147 4.4 4.4 signal
277 Rash Maculo-papular 53 4.4 4.4 signal
278 Off Label Use 2,073 4.3 5.1 signal
279 Transaminases Increased 53 4.3 4.4 signal
280 Metastatic Neoplasm 10 4.2 4.2 signal
281 Faeces Hard 9 4.2 4.2 signal
282 Lower Gastrointestinal Haemorrhage 17 4.2 4.2 signal
283 Weight Decreased 636 4.1 4.3 signal
284 Fatigue 1,769 4.1 4.7 signal
285 Intestinal Obstruction 85 4.1 4.2 signal
286 General Physical Health Deterioration 260 4.1 4.2 signal
287 Musculoskeletal Chest Pain 35 4.1 4.1 signal
288 Skin Disorder 75 4.1 4.1 signal
289 Large Intestinal Obstruction 5 4.1 4.1 signal
290 Temperature Intolerance 23 4.1 4.1 signal
291 Hyperthermia 17 4.1 4.1 signal
292 Mouth Ulceration 47 4.1 4.1 signal
293 Blood Sodium Decreased 42 4.1 4.1 signal
294 Hepatic Cancer 54 4.0 4.1 signal
295 Peripheral Sensory Neuropathy 13 4.0 4.1 signal
296 Cheilitis 12 4.0 4.0 signal
297 Faeces Soft 16 4.0 4.0 signal
298 Diarrhoea 1,418 4.0 4.4 signal
299 Blood Phosphorus Decreased 8 4.0 4.0 signal
300 Oral Fungal Infection 6 4.0 4.0 signal
301 Amylase Increased 8 4.0 4.0 signal
302 Therapy Change 21 4.0 4.0 signal
303 Melaena 48 4.0 4.0 signal
304 Pyrexia 752 4.0 4.2 signal
305 Hyperpyrexia 9 3.9 4.0 signal
306 Liver Abscess 7 3.9 3.9 signal
307 Liver Function Test Increased 46 3.9 3.9 signal
308 Blood Count Abnormal 33 3.9 3.9 signal
309 Proctitis 6 3.9 3.9 signal
310 Skin Abrasion 10 3.9 3.9 signal
311 Colorectal Cancer Stage Iv 10 3.9 3.9 signal
312 Hospice Care 21 3.9 3.9 signal
313 Hepatomegaly 21 3.9 3.9 signal
314 Dry Mouth 172 3.9 3.9 signal
315 Transfusion 22 3.8 3.8 signal
316 Pulmonary Pain 6 3.8 3.8 signal
317 Oral Discomfort 29 3.8 3.8 signal
318 Slow Speech 5 3.8 3.8 signal
319 Painful Respiration 5 3.8 3.8 signal
320 Abdominal Pain 481 3.8 3.9 signal
321 Hepatic Cyst 7 3.8 3.8 signal
322 C-reactive Protein Increased 75 3.8 3.8 signal
323 Blood Thyroid Stimulating Hormone Increased 19 3.7 3.7 signal
324 Altered State Of Consciousness 44 3.7 3.7 signal
325 Hospitalisation 310 3.7 3.8 signal
326 Pneumothorax 32 3.7 3.7 signal
327 Blood Lactate Dehydrogenase Increased 32 3.7 3.7 signal
328 Dry Skin 263 3.6 3.7 signal
329 Varices Oesophageal 6 3.6 3.6 signal
330 Faeces Discoloured 43 3.6 3.6 signal
331 Liver Function Test Abnormal 58 3.6 3.6 signal
332 Toxic Skin Eruption 20 3.6 3.6 signal
333 Constipation 427 3.6 3.7 signal
334 Catheter Site Pain 5 3.6 3.6 signal
335 Abdominal Infection 5 3.6 3.6 signal
336 Hiccups 16 3.6 3.6 signal
337 Blood Potassium Decreased 59 3.6 3.6 signal
338 Encephalopathy 48 3.6 3.6 signal
339 Blood Pressure Fluctuation 47 3.6 3.6 signal
340 Malignant Neoplasm Progression 198 3.5 3.6 signal
341 Urine Output Decreased 17 3.5 3.5 signal
342 Neoplasm Progression 68 3.5 3.5 signal
343 Aortic Dissection 8 3.5 3.5 signal
344 Blood Creatinine Decreased 6 3.5 3.5 signal
345 Skin Lesion 52 3.5 3.5 signal
346 Neoplasm 22 3.5 3.5 signal
347 Neurotoxicity 33 3.5 3.5 signal
348 Muscle Fatigue 8 3.4 3.4 signal
349 Limb Discomfort 58 3.4 3.4 signal
350 Ventricular Hypokinesia 6 3.4 3.4 signal
351 Protein Total Decreased 7 3.4 3.4 signal
352 Loss Of Personal Independence In Daily Activities 88 3.4 3.4 signal
353 Blood Urine Present 35 3.3 3.3 signal
354 Abdominal Pain Upper 375 3.3 3.4 signal
355 Gait Disturbance 350 3.3 3.4 signal
356 Cholecystitis Infective 5 3.3 3.3 signal
357 Pleuritic Pain 5 3.3 3.3 signal
358 Nail Discolouration 7 3.3 3.3 signal
359 Neoplasm Recurrence 6 3.2 3.2 signal
360 Obstruction 7 3.2 3.2 signal
361 Skin Papilloma 7 3.2 3.2 signal
362 Biliary Colic 5 3.2 3.2 signal
363 Disease Complication 8 3.2 3.2 signal
364 Epistaxis 130 3.2 3.2 signal
365 Gastrointestinal Pain 19 3.2 3.2 signal
366 Failure To Thrive 9 3.1 3.1 signal
367 Blood Pressure Diastolic Increased 8 3.1 3.1 signal
368 Small Intestinal Obstruction 21 3.1 3.1 signal
369 Bone Marrow Failure 35 3.1 3.1 signal
370 Hyperuricaemia 7 3.1 3.1 signal
371 Generalised Oedema 21 3.1 3.1 signal
372 Hypertensive Crisis 19 3.1 3.1 signal
373 Incoherent 11 3.1 3.1 signal
374 Acute Hepatic Failure 23 3.1 3.1 signal
375 Red Cell Distribution Width Increased 7 3.1 3.1 signal
376 Hypovolaemic Shock 8 3.1 3.1 signal
377 Dyspnoea Exertional 63 3.1 3.1 signal
378 Adverse Drug Reaction 150 3.0 3.1 signal
379 Embolism 14 3.0 3.1 signal
380 Burning Sensation 116 3.0 3.0 signal
381 Poor Peripheral Circulation 7 3.0 3.0 signal
382 Incorrect Dosage Administered 8 3.0 3.0 signal
383 Tearfulness 7 2.9 2.9 signal
384 Chest X-ray Abnormal 5 2.9 2.9 signal
385 Gingival Bleeding 22 2.9 2.9 signal
386 Rectal Haemorrhage 69 2.9 2.9 signal
387 Taste Disorder 32 2.9 2.9 signal
388 Cerebral Infarction 39 2.9 2.9 signal
389 Myocarditis 18 2.9 2.9 signal
390 Bile Duct Stone 5 2.9 2.9 signal
391 Blood Pressure Systolic Increased 31 2.9 2.9 signal
392 Systemic Inflammatory Response Syndrome 6 2.9 2.9 signal
393 Oropharyngeal Pain 146 2.9 2.9 signal
394 Enterocolitis 9 2.9 2.9 signal
395 Dry Throat 16 2.9 2.9 signal
396 Musculoskeletal Disorder 30 2.9 2.9 signal
397 Blood Test Abnormal 22 2.8 2.9 signal
398 Orthopnoea 5 2.8 2.8 signal
399 Paranasal Sinus Hypersecretion 6 2.8 2.8 signal
400 Skin Discolouration 71 2.8 2.8 signal
401 Peritonitis 32 2.8 2.8 signal
402 Haematochezia 85 2.8 2.8 signal
403 Poor Quality Sleep 33 2.8 2.8 signal
404 Haemoptysis 43 2.8 2.8 signal
405 Dysstasia 45 2.8 2.8 signal
406 Liver Injury 37 2.8 2.8 signal
407 Epigastric Discomfort 6 2.8 2.8 signal
408 Local Swelling 27 2.8 2.8 signal
409 Brain Neoplasm 14 2.8 2.8 signal
410 Mobility Decreased 108 2.7 2.8 signal
411 White Blood Cell Count Increased 58 2.7 2.7 signal
412 Skin Weeping 5 2.7 2.7 no signal
413 Peripheral Swelling 230 2.7 2.8 signal
414 Flank Pain 14 2.7 2.7 signal
415 Rash Erythematous 70 2.7 2.7 signal
416 Cerebral Haematoma 5 2.7 2.7 no signal
417 Erythema 302 2.7 2.7 signal
418 Gastric Haemorrhage 17 2.7 2.7 signal
419 Hyperthyroidism 21 2.6 2.6 signal
420 Hepatitis 37 2.6 2.6 signal
421 Gamma-glutamyltransferase Increased 32 2.6 2.6 signal
422 Thyroid Function Test Abnormal 6 2.6 2.6 signal
423 Drug Intolerance 138 2.6 2.6 signal
424 Aphthous Ulcer 11 2.6 2.6 signal
425 Carotid Artery Stenosis 5 2.6 2.6 no signal
426 Renal Pain 15 2.6 2.6 signal
427 Thrombocytopenia 158 2.6 2.6 signal
428 Haematemesis 36 2.6 2.6 signal
429 Urinary Retention 47 2.6 2.6 signal
430 Rash Macular 49 2.6 2.6 signal
431 Hepatic Enzyme Abnormal 7 2.6 2.6 signal
432 Haemorrhage Subcutaneous 5 2.6 2.6 no signal
433 Haemorrhagic Diathesis 5 2.5 2.5 no signal
434 Drug-induced Liver Injury 43 2.5 2.5 signal
435 Electrolyte Imbalance 16 2.5 2.5 signal
436 Coronary Artery Stenosis 7 2.5 2.5 signal
437 Anuria 12 2.5 2.5 signal
438 Renal Impairment 116 2.5 2.5 signal
439 Chapped Lips 6 2.5 2.5 signal
440 Hypomagnesaemia 19 2.5 2.5 signal
441 Food Intolerance 5 2.5 2.5 no signal
442 Drug Eruption 24 2.5 2.5 signal
443 Oral Disorder 10 2.5 2.5 signal
444 Blood Iron Decreased 16 2.5 2.5 signal
445 Partial Seizures 7 2.5 2.5 signal
446 Ejection Fraction Decreased 21 2.5 2.5 signal
447 Haemorrhagic Anaemia 6 2.4 2.4 no signal
448 Wheelchair User 6 2.4 2.4 no signal
449 Abnormal Faeces 11 2.4 2.4 signal
450 Tenderness 14 2.4 2.4 signal
451 Abdominal Distension 139 2.4 2.4 signal
452 Blood Calcium Decreased 15 2.4 2.4 signal
453 Squamous Cell Carcinoma Of Skin 8 2.4 2.4 signal
454 Hepatic Enzyme Increased 90 2.4 2.4 signal
455 Drug Resistance 34 2.4 2.4 signal
456 Blood Pressure Inadequately Controlled 8 2.4 2.4 signal
457 Anal Fissure 7 2.4 2.4 signal
458 Sepsis 146 2.4 2.4 signal
459 Myocardial Ischaemia 15 2.4 2.4 signal
460 Motor Dysfunction 13 2.3 2.3 signal
461 Disorientation 51 2.3 2.3 signal
462 Rash 556 2.3 2.4 signal
463 Umbilical Hernia 6 2.3 2.3 no signal
464 Venous Thrombosis 5 2.3 2.3 no signal
465 Dysphagia 120 2.3 2.3 signal
466 Dermatitis Bullous 9 2.3 2.3 signal
467 Haemophagocytic Lymphohistiocytosis 9 2.3 2.3 signal
468 Nocturia 15 2.3 2.3 signal
469 Hepatitis Acute 8 2.2 2.2 signal
470 Tongue Disorder 9 2.2 2.2 signal
471 Trigger Finger 5 2.2 2.2 no signal
472 Lip Dry 11 2.2 2.2 signal
473 Decubitus Ulcer 10 2.2 2.2 signal
474 Laboratory Test Abnormal 36 2.2 2.2 signal
475 Pancreatic Disorder 6 2.2 2.2 no signal
476 Haemorrhoidal Haemorrhage 6 2.2 2.2 no signal
477 Vomiting 570 2.2 2.3 signal
478 International Normalised Ratio Increased 35 2.2 2.2 signal
479 Hypoaesthesia 182 2.2 2.2 signal
480 Stevens-johnson Syndrome 27 2.2 2.2 signal
481 Flatulence 68 2.2 2.2 signal
482 Back Pain 279 2.2 2.2 signal
483 Splenomegaly 14 2.2 2.2 signal
484 Troponin Increased 9 2.2 2.2 signal
485 Postoperative Wound Infection 8 2.2 2.2 no signal
486 Urine Odour Abnormal 7 2.2 2.2 no signal
487 Night Sweats 38 2.1 2.1 signal
488 Malnutrition 13 2.1 2.1 signal
489 Purulent Discharge 5 2.1 2.1 no signal
490 Product Administered To Patient Of Inappropriate Age 7 2.1 2.1 no signal
491 Death 1,001 2.1 2.2 signal
492 Confusional State 188 2.1 2.1 signal
493 Dermatitis 24 2.1 2.1 signal
494 Prothrombin Time Prolonged 7 2.1 2.1 no signal
495 Gastric Ulcer 22 2.1 2.1 signal
496 Cerebral Ischaemia 6 2.1 2.1 no signal
497 Neuralgia 28 2.1 2.1 signal
498 Oral Candidiasis 15 2.1 2.1 signal
499 Oedema Peripheral 141 2.1 2.1 signal
500 Pleural Effusion 70 2.1 2.1 signal
501 Full Blood Count Abnormal 12 2.1 2.1 signal
502 Haematuria 39 2.1 2.1 signal
503 Pigmentation Disorder 7 2.1 2.1 no signal
504 Thrombotic Microangiopathy 11 2.1 2.1 signal
505 Product Supply Issue 8 2.1 2.1 no signal
506 Inflammation 58 2.1 2.1 signal
507 Haemorrhoids 22 2.0 2.0 signal
508 Hepatic Cirrhosis 21 2.0 2.0 signal
509 Anal Incontinence 10 2.0 2.0 signal
510 Paraesthesia Oral 16 2.0 2.0 signal
511 Dysuria 41 2.0 2.0 signal
512 Feeling Cold 31 2.0 2.0 signal
513 Gingivitis 6 2.0 2.0 no signal
514 Shock Haemorrhagic 9 2.0 2.0 no signal
515 Muscle Spasms 202 2.0 2.0 signal
516 Abdominal Hernia 5 2.0 2.0 no signal
517 Gastrointestinal Carcinoma 10 2.0 2.0 no signal
518 Renal Function Test Abnormal 5 2.0 2.0 no signal
519 Urosepsis 10 2.0 2.0 no signal
520 Red Blood Cell Count Decreased 31 2.0 2.0 no signal
521 Localised Oedema 5 2.0 2.0 no signal
522 Ear Discomfort 11 2.0 2.0 no signal
523 Pneumonitis 29 1.9 2.0 no signal
524 Interstitial Lung Disease 51 1.9 1.9 no signal
525 Left Ventricular Dysfunction 7 1.9 1.9 no signal
526 Subcutaneous Abscess 5 1.9 1.9 no signal
527 Frequent Bowel Movements 28 1.9 1.9 no signal
528 Therapy Cessation 53 1.9 1.9 no signal
529 Haemolysis 8 1.9 1.9 no signal
530 Nausea 815 1.9 1.9 no signal
531 Body Temperature Increased 21 1.9 1.9 no signal
532 Faecal Incontinence 5 1.9 1.9 no signal
533 Feeling Of Body Temperature Change 6 1.9 1.9 no signal
534 Onychoclasis 7 1.9 1.9 no signal
535 Anaemia 194 1.8 1.9 no signal
536 Energy Increased 6 1.8 1.8 no signal
537 Oropharyngeal Discomfort 9 1.8 1.8 no signal
538 Lung Disorder 49 1.8 1.8 no signal
539 Hyponatraemia 56 1.8 1.8 no signal
540 Cholestasis 19 1.8 1.8 no signal
541 Lymphadenopathy 35 1.8 1.8 no signal
542 Nephropathy Toxic 11 1.8 1.8 no signal
543 Chills 115 1.8 1.8 no signal
544 Thyroid Disorder 15 1.8 1.8 no signal
545 Neutrophil Count Increased 10 1.8 1.8 no signal
546 Mental Status Changes 27 1.8 1.8 no signal
547 Quality Of Life Decreased 13 1.8 1.8 no signal
548 Oliguria 6 1.8 1.8 no signal
549 Increased Upper Airway Secretion 5 1.8 1.8 no signal
550 Renal Disorder 45 1.8 1.8 no signal
551 Tooth Extraction 12 1.8 1.8 no signal
552 Hemiplegia 8 1.7 1.7 no signal
553 Nasal Dryness 6 1.7 1.7 no signal
554 Colitis 36 1.7 1.7 no signal
555 Mouth Haemorrhage 7 1.7 1.7 no signal
556 Lung Infection 15 1.7 1.7 no signal
557 Cerebral Haemorrhage 34 1.7 1.7 no signal
558 Brain Oedema 12 1.7 1.7 no signal
559 Blood Creatinine Increased 62 1.7 1.7 no signal
560 Neutrophil Count Decreased 38 1.7 1.7 no signal
561 Malaise 410 1.7 1.7 no signal
562 Productive Cough 44 1.7 1.7 no signal
563 Toxic Epidermal Necrolysis 14 1.7 1.7 no signal
564 Musculoskeletal Pain 49 1.7 1.7 no signal
565 Muscular Weakness 105 1.7 1.7 no signal
566 Cytopenia 11 1.7 1.7 no signal
567 Wound Infection 10 1.7 1.7 no signal
568 Paraesthesia 145 1.7 1.7 no signal
569 Urinary Tract Infection 156 1.7 1.7 no signal
570 Speech Disorder 48 1.7 1.7 no signal
571 Angina Unstable 6 1.7 1.7 no signal
572 Product Use Issue 171 1.7 1.7 no signal
573 Groin Pain 8 1.6 1.6 no signal
574 Abdominal Pain Lower 23 1.6 1.6 no signal
575 Bone Pain 53 1.6 1.6 no signal
576 Coagulopathy 15 1.6 1.6 no signal
577 Cardiotoxicity 8 1.6 1.6 no signal
578 Hypocalcaemia 17 1.6 1.6 no signal
579 Activities Of Daily Living Impaired 18 1.6 1.6 no signal
580 Pulmonary Haemorrhage 7 1.6 1.6 no signal
581 Chest Pain 166 1.6 1.6 no signal
582 Limb Injury 24 1.6 1.6 no signal
583 Leukocytosis 16 1.6 1.6 no signal
584 Cholecystitis Acute 5 1.6 1.6 no signal
585 Renal Cyst 7 1.6 1.6 no signal
586 Septic Shock 38 1.6 1.6 no signal
587 Pain 539 1.6 1.6 no signal
588 Internal Haemorrhage 10 1.6 1.6 no signal
589 Peripheral Coldness 12 1.6 1.6 no signal
590 Mouth Swelling 5 1.6 1.6 no signal
591 Pancreatitis 46 1.6 1.6 no signal
592 Rhinitis 7 1.6 1.6 no signal
593 Kidney Infection 17 1.6 1.6 no signal
594 Blood Potassium Increased 14 1.6 1.6 no signal
595 Blood Pressure Abnormal 17 1.6 1.6 no signal
596 White Blood Cell Count Decreased 93 1.6 1.6 no signal
597 Mass 12 1.6 1.6 no signal
598 Hypovolaemia 5 1.6 1.6 no signal
599 Lethargy 49 1.5 1.6 no signal
600 Pancreatitis Acute 19 1.5 1.5 no signal
601 Duodenal Ulcer 6 1.5 1.5 no signal
602 Alopecia 167 1.5 1.6 no signal
603 Hepatocellular Injury 12 1.5 1.5 no signal
604 Candida Infection 14 1.5 1.5 no signal
605 Pleurisy 5 1.5 1.5 no signal
606 Pharyngeal Swelling 8 1.5 1.5 no signal
607 Myalgia 142 1.5 1.5 no signal
608 Spinal Compression Fracture 7 1.5 1.5 no signal
609 Gastrointestinal Haemorrhage 70 1.5 1.5 no signal
610 Oedema 45 1.5 1.5 no signal
611 Dyspnoea 468 1.5 1.5 no signal
612 Wound 23 1.5 1.5 no signal
613 Facial Paralysis 7 1.5 1.5 no signal
614 Pelvic Pain 15 1.5 1.5 no signal
615 Gangrene 5 1.5 1.5 no signal
616 Pyelonephritis 7 1.5 1.5 no signal
617 Tachycardia 72 1.5 1.5 no signal
618 Delirium 28 1.5 1.5 no signal
619 Rash Papular 18 1.5 1.5 no signal
620 Tumour Lysis Syndrome 7 1.5 1.5 no signal
621 Retching 17 1.5 1.5 no signal
622 Heart Rate Increased 79 1.4 1.5 no signal
623 Scab 9 1.4 1.4 no signal
624 Micturition Urgency 9 1.4 1.4 no signal
625 Impaired Healing 26 1.4 1.4 no signal
626 Purpura 7 1.4 1.4 no signal
627 Gastrointestinal Infection 7 1.4 1.4 no signal
628 Acute Respiratory Failure 15 1.4 1.4 no signal
629 Coordination Abnormal 11 1.4 1.4 no signal
630 Leukopenia 39 1.4 1.4 no signal
631 Myositis 7 1.4 1.4 no signal
632 Urinary Incontinence 23 1.4 1.4 no signal
633 Product Use Complaint 12 1.4 1.4 no signal
634 Cough 215 1.4 1.4 no signal
635 Dysgeusia 57 1.4 1.4 no signal
636 Balance Disorder 66 1.4 1.4 no signal
637 Product Use In Unapproved Indication 186 1.4 1.4 no signal
638 Sciatica 12 1.4 1.4 no signal
639 Incontinence 8 1.4 1.4 no signal
640 Walking Aid User 5 1.4 1.4 no signal
641 Product Label Issue 5 1.4 1.4 no signal
642 Colitis Ischaemic 5 1.4 1.4 no signal
643 Hypokalaemia 34 1.3 1.3 no signal
644 Incorrect Product Administration Duration 15 1.3 1.3 no signal
645 General Physical Condition Abnormal 5 1.3 1.3 no signal
646 Product Packaging Quantity Issue 8 1.3 1.3 no signal
647 Encephalitis 5 1.3 1.3 no signal
648 Lymphoedema 5 1.3 1.3 no signal
649 Central Nervous System Lesion 10 1.3 1.3 no signal
650 Autoimmune Hepatitis 5 1.3 1.3 no signal
651 Dermatitis Allergic 9 1.3 1.3 no signal
652 Hair Growth Abnormal 5 1.3 1.3 no signal
653 Second Primary Malignancy 6 1.3 1.3 no signal
654 Acute Coronary Syndrome 6 1.3 1.3 no signal
655 Haemoglobin Decreased 74 1.3 1.3 no signal
656 Blood Creatine Phosphokinase Increased 21 1.3 1.3 no signal
657 Defaecation Urgency 5 1.3 1.3 no signal
658 Pulmonary Embolism 68 1.3 1.3 no signal
659 Upper Gastrointestinal Haemorrhage 12 1.3 1.3 no signal
660 Acute Myocardial Infarction 21 1.3 1.3 no signal
661 Neutropenia 96 1.3 1.3 no signal
662 Face Oedema 12 1.3 1.3 no signal
663 Skin Swelling 6 1.3 1.3 no signal
664 Thermal Burn 5 1.3 1.3 no signal
665 Vitamin D Decreased 6 1.3 1.3 no signal
666 Musculoskeletal Discomfort 12 1.3 1.3 no signal
667 Thinking Abnormal 13 1.3 1.3 no signal
668 Nail Disorder 6 1.3 1.3 no signal
669 Headache 431 1.3 1.3 no signal
670 Apathy 10 1.3 1.3 no signal
671 Depressed Level Of Consciousness 27 1.2 1.2 no signal
672 Blood Calcium Increased 6 1.2 1.2 no signal
673 Spinal Pain 8 1.2 1.2 no signal
674 Rash Pustular 5 1.2 1.2 no signal
675 Ageusia 17 1.2 1.2 no signal
676 Neck Pain 38 1.2 1.2 no signal
677 Adverse Reaction 9 1.2 1.2 no signal
678 Thirst 12 1.2 1.2 no signal
679 Facial Pain 6 1.2 1.2 no signal
680 Labelled Drug-drug Interaction Medication Error 6 1.2 1.2 no signal
681 Sunburn 5 1.2 1.2 no signal
682 Hypoaesthesia Oral 10 1.2 1.2 no signal
683 Haemorrhage 69 1.2 1.2 no signal
684 Pneumonia Bacterial 6 1.2 1.2 no signal
685 Pneumonia 212 1.2 1.2 no signal
686 Surgery 38 1.2 1.2 no signal
687 Acidosis 5 1.2 1.2 no signal
688 Impaired Work Ability 14 1.2 1.2 no signal
689 Retinal Detachment 6 1.2 1.2 no signal
690 Device Related Infection 10 1.2 1.2 no signal
691 Secretion Discharge 8 1.2 1.2 no signal
692 Atrial Fibrillation 63 1.2 1.2 no signal
693 Hemiparesis 11 1.2 1.2 no signal
694 Multiple Organ Dysfunction Syndrome 18 1.2 1.2 no signal
695 Gastrointestinal Disorder 57 1.2 1.2 no signal
696 Acute Kidney Injury 98 1.2 1.2 no signal
697 Pulmonary Thrombosis 7 1.2 1.2 no signal
698 Oesophagitis 7 1.2 1.2 no signal
699 Hair Colour Changes 8 1.2 1.2 no signal
700 Cardiac Failure 51 1.2 1.2 no signal
701 Dyspepsia 62 1.1 1.1 no signal
702 Skin Irritation 29 1.1 1.1 no signal
703 Respiratory Tract Congestion 10 1.1 1.1 no signal
704 Discomfort 38 1.1 1.1 no signal
705 Product Availability Issue 14 1.1 1.1 no signal
706 Atrial Flutter 5 1.1 1.1 no signal
707 Blood Disorder 5 1.1 1.1 no signal
708 Fistula 7 1.1 1.1 no signal
709 Stent Placement 5 1.1 1.1 no signal
710 Mental Impairment 15 1.1 1.1 no signal
711 Platelet Count Increased 8 1.1 1.1 no signal
712 Immunodeficiency 9 1.1 1.1 no signal
713 Abdominal Discomfort 102 1.1 1.1 no signal
714 Upper-airway Cough Syndrome 5 1.1 1.1 no signal
715 Pericardial Effusion 14 1.1 1.1 no signal
716 Bladder Disorder 6 1.1 1.1 no signal
717 Hyperkalaemia 21 1.1 1.1 no signal
718 Prescribed Underdose 12 1.1 1.1 no signal
719 Hypoglycaemia 29 1.1 1.1 no signal
720 Deep Vein Thrombosis 39 1.1 1.1 no signal
721 Infection 86 1.1 1.1 no signal
722 Aphasia 18 1.1 1.1 no signal
723 Pruritus Generalised 13 1.1 1.1 no signal
724 Hypothermia 6 1.1 1.1 no signal
725 Sluggishness 6 1.1 1.1 no signal
726 Pseudomonas Infection 5 1.1 1.1 no signal
727 Tachypnoea 8 1.1 1.1 no signal
728 Initial Insomnia 6 1.1 1.1 no signal
729 Illness 59 1.1 1.1 no signal
730 Drug Reaction With Eosinophilia And Systemic Symptoms 15 1.1 1.1 no signal
731 Thrombosis 47 1.1 1.1 no signal
732 Muscle Strain 5 1.1 1.1 no signal
733 Pollakiuria 24 1.0 1.0 no signal
734 Renal Failure 77 1.0 1.0 no signal
735 Grip Strength Decreased 5 1.0 1.0 no signal
736 Feeling Hot 35 1.0 1.0 no signal
737 Lymphopenia 8 1.0 1.0 no signal
738 Arrhythmia 27 1.0 1.0 no signal
739 Hypercalcaemia 7 1.0 1.0 no signal
740 Lung Infiltration 5 1.0 1.0 no signal
741 Febrile Neutropenia 37 1.0 1.0 no signal
742 Skin Haemorrhage 8 1.0 1.0 no signal
743 Aspiration 6 1.0 1.0 no signal
744 Depressed Mood 29 1.0 1.0 no signal
745 Unresponsive To Stimuli 14 1.0 1.0 no signal
746 Cardiomyopathy 8 1.0 1.0 no signal
747 Skin Infection 6 1.0 1.0 no signal
748 Localised Infection 13 1.0 1.0 no signal
749 Personality Change 5 1.0 1.0 no signal
750 Hypotension 107 1.0 1.0 no signal
751 Arthralgia 221 1.0 1.0 no signal
752 Therapeutic Response Unexpected 24 1.0 1.0 no signal
753 Hypercholesterolaemia 5 0.9 0.9 no signal
754 Hunger 7 0.9 0.9 no signal
755 Eosinophilia 9 0.9 0.9 no signal
756 Pallor 14 0.9 0.9 no signal
757 Multi-organ Failure 9 0.9 0.9 no signal
758 Swollen Tongue 16 0.9 0.9 no signal
759 Cold Sweat 9 0.9 0.9 no signal
760 Acute Respiratory Distress Syndrome 9 0.9 0.9 no signal
761 Polyneuropathy 6 0.9 0.9 no signal
762 Dizziness 251 0.9 0.9 no signal
763 Coma 24 0.9 0.9 no signal
764 Insomnia 134 0.9 0.9 no signal
765 Toothache 9 0.9 0.9 no signal
766 Somnolence 100 0.9 0.9 no signal
767 Peritonitis Bacterial 5 0.9 0.9 no signal
768 Sensory Disturbance 8 0.9 0.9 no signal
769 Cognitive Disorder 23 0.9 0.9 no signal
770 Sinus Tachycardia 7 0.9 0.9 no signal
771 Dialysis 7 0.9 0.9 no signal
772 Throat Irritation 22 0.9 0.9 no signal
773 Eyelid Ptosis 5 0.9 0.9 no signal
774 Epilepsy 15 0.9 0.9 no signal
775 Gastric Disorder 17 0.9 0.9 no signal
776 Cholelithiasis 16 0.9 0.9 no signal
777 Paralysis 7 0.9 0.9 no signal
778 No Therapeutic Response 6 0.9 0.9 no signal
779 Bacterial Infection 9 0.9 0.9 no signal
780 Heart Rate Irregular 11 0.9 0.9 no signal
781 Folliculitis 5 0.9 0.9 no signal
782 Loss Of Consciousness 62 0.9 0.9 no signal
783 Scratch 5 0.9 0.9 no signal
784 Rash Pruritic 26 0.9 0.9 no signal
785 Ventricular Extrasystoles 5 0.9 0.9 no signal
786 Increased Appetite 9 0.9 0.9 no signal
787 Product Dose Omission 31 0.9 0.8 no signal
788 Sudden Death 5 0.8 0.8 no signal
789 Drug Interaction 74 0.8 0.8 no signal
790 Ear Pain 9 0.8 0.8 no signal
791 Chest Discomfort 47 0.8 0.8 no signal
792 Laryngitis 5 0.8 0.8 no signal
793 Amnesia 30 0.8 0.8 no signal
794 Gastritis 12 0.8 0.8 no signal
795 Immune System Disorder 6 0.8 0.8 no signal
796 Intentional Product Use Issue 40 0.8 0.8 no signal
797 Head Discomfort 8 0.8 0.8 no signal
798 Hallucination 34 0.8 0.8 no signal
799 Blood Pressure Decreased 30 0.8 0.8 no signal
800 Lymphocyte Count Decreased 8 0.8 0.8 no signal
801 Respiratory Failure 33 0.8 0.8 no signal
802 Haematocrit Decreased 9 0.8 0.8 no signal
803 Fungal Infection 15 0.8 0.8 no signal
804 Hyperhidrosis 58 0.8 0.8 no signal
805 Unevaluable Event 34 0.8 0.8 no signal
806 Feeling Abnormal 108 0.8 0.8 no signal
807 Joint Range Of Motion Decreased 6 0.8 0.8 no signal
808 Pharyngeal Oedema 7 0.8 0.8 no signal
809 Ischaemic Stroke 8 0.8 0.8 no signal
810 Full Blood Count Decreased 9 0.8 0.8 no signal
811 Tremor 74 0.8 0.8 no signal
812 Sinus Congestion 6 0.8 0.8 no signal
813 Toxicity To Various Agents 74 0.8 0.8 no signal
814 Ulcer 7 0.8 0.8 no signal
815 Impaired Driving Ability 5 0.8 0.8 no signal
816 Fall 146 0.8 0.8 no signal
817 Abscess 7 0.8 0.8 no signal
818 Cystitis 14 0.8 0.8 no signal
819 Increased Tendency To Bruise 4 0.8 0.8 no signal
820 Musculoskeletal Stiffness 38 0.8 0.8 no signal
821 Fluid Retention 22 0.8 0.8 no signal
822 Device Occlusion 6 0.8 0.8 no signal
823 Photophobia 8 0.8 0.8 no signal
824 Post Procedural Haemorrhage 5 0.8 0.8 no signal
825 Eyelid Oedema 5 0.8 0.8 no signal
826 Diarrhoea Haemorrhagic 4 0.8 0.8 no signal
827 Eye Inflammation 4 0.8 0.8 no signal
828 Pruritus 159 0.8 0.8 no signal
829 Eructation 8 0.8 0.8 no signal
830 Deafness 11 0.8 0.8 no signal
831 Neoplasm Malignant 28 0.8 0.8 no signal
832 Angina Pectoris 12 0.8 0.8 no signal
833 Presyncope 10 0.8 0.8 no signal
834 Hyperglycaemia 15 0.8 0.7 no signal
835 Skin Burning Sensation 29 0.7 0.7 no signal
836 Contusion 39 0.7 0.7 no signal
837 Salivary Hypersecretion 4 0.7 0.7 no signal
838 Incorrect Dose Administered 90 0.7 0.7 no signal
839 Dysarthria 15 0.7 0.7 no signal
840 Respiratory Distress 11 0.7 0.7 no signal
841 Vaginal Discharge 4 0.7 0.7 no signal
842 Diverticulitis 11 0.7 0.7 no signal
843 Eye Discharge 4 0.7 0.7 no signal
844 Viral Infection 13 0.7 0.7 no signal
845 Rhinorrhoea 25 0.7 0.7 no signal
846 Diplopia 10 0.7 0.7 no signal
847 Rhabdomyolysis 16 0.7 0.7 no signal
848 Nodule 5 0.7 0.7 no signal
849 Visual Impairment 47 0.7 0.7 no signal
850 Restlessness 14 0.7 0.7 no signal
851 Cardio-respiratory Arrest 16 0.7 0.7 no signal
852 Adverse Event 35 0.7 0.7 no signal
853 Oxygen Saturation Decreased 21 0.7 0.7 no signal
854 Middle Insomnia 7 0.7 0.7 no signal
855 Movement Disorder 12 0.7 0.7 no signal
856 Renal Failure Acute 16 0.7 0.7 no signal
857 Hair Texture Abnormal 5 0.7 0.7 no signal
858 Cardiac Disorder 34 0.7 0.7 no signal
859 Memory Impairment 49 0.6 0.6 no signal
860 Disability 7 0.6 0.6 no signal
861 Myocardial Infarction 62 0.6 0.6 no signal
862 Abnormal Behaviour 14 0.6 0.6 no signal
863 Hypersensitivity 65 0.6 0.6 no signal
864 Nephrolithiasis 16 0.6 0.6 no signal
865 Gastrooesophageal Reflux Disease 28 0.6 0.6 no signal
866 Seizure 40 0.6 0.6 no signal
867 Urticaria 58 0.6 0.6 no signal
868 Muscle Twitching 8 0.6 0.6 no signal
869 Hypoxia 12 0.6 0.6 no signal
870 Drug Ineffective For Unapproved Indication 19 0.6 0.6 no signal
871 Drug Ineffective 444 0.6 0.6 no signal
872 Vision Blurred 46 0.6 0.6 no signal
873 Product Dose Omission In Error 9 0.6 0.6 no signal
874 Drug Dose Omission 56 0.6 0.6 no signal
875 Gout 6 0.6 0.6 no signal
876 Hallucination, Visual 7 0.6 0.6 no signal
877 Respiratory Disorder 10 0.6 0.6 no signal
878 Throat Tightness 9 0.6 0.6 no signal
879 Renal Injury 10 0.6 0.6 no signal
880 Spinal Operation 4 0.6 0.6 no signal
881 Herpes Zoster 19 0.6 0.6 no signal
882 Bone Loss 5 0.6 0.6 no signal
883 Vertigo 20 0.6 0.6 no signal
884 Hepatic Cytolysis 4 0.6 0.6 no signal
885 Dementia 9 0.6 0.6 no signal
886 Pancytopenia 18 0.6 0.6 no signal
887 Tendonitis 5 0.6 0.6 no signal
888 Poisoning 4 0.6 0.6 no signal
889 Head Injury 10 0.6 0.6 no signal
890 Product Dose Omission Issue 90 0.6 0.6 no signal
891 Acne 24 0.6 0.6 no signal
892 Pulmonary Fibrosis 6 0.6 0.6 no signal
893 Sneezing 7 0.6 0.6 no signal
894 Swelling 29 0.6 0.6 no signal
895 Muscle Tightness 5 0.6 0.6 no signal
896 Oral Herpes 6 0.6 0.6 no signal
897 Palpitations 36 0.6 0.6 no signal
898 Swelling Face 20 0.6 0.6 no signal
899 Shock 7 0.6 0.6 no signal
900 Vaginal Haemorrhage 13 0.6 0.6 no signal
901 Hot Flush 23 0.6 0.6 no signal
902 Photosensitivity Reaction 5 0.6 0.6 no signal
903 Cerebrovascular Accident 51 0.5 0.5 no signal
904 Intentional Product Misuse 26 0.5 0.5 no signal
905 Blood Urea Increased 5 0.5 0.5 no signal
906 Blindness 12 0.5 0.5 no signal
907 Treatment Failure 24 0.5 0.5 no signal
908 Rib Fracture 6 0.5 0.5 no signal
909 Joint Swelling 35 0.5 0.5 no signal
910 Blood Glucose Decreased 14 0.5 0.5 no signal
911 Influenza 32 0.5 0.5 no signal
912 Sleep Disorder 20 0.5 0.5 no signal
913 Cardiac Failure Congestive 23 0.5 0.5 no signal
914 Pain In Jaw 8 0.5 0.5 no signal
915 Clostridium Difficile Infection 6 0.5 0.5 no signal
916 Gastroenteritis Viral 5 0.5 0.5 no signal
917 Product Dispensing Error 6 0.5 0.5 no signal
918 Restless Legs Syndrome 5 0.5 0.5 no signal
919 Cardiovascular Disorder 7 0.5 0.5 no signal
920 Erectile Dysfunction 7 0.5 0.5 no signal
921 Agranulocytosis 5 0.5 0.5 no signal
922 Syncope 27 0.5 0.5 no signal
923 Respiratory Tract Infection 7 0.5 0.5 no signal
924 Therapy Non-responder 12 0.5 0.5 no signal
925 Tubulointerstitial Nephritis 5 0.5 0.5 no signal
926 Joint Stiffness 7 0.5 0.5 no signal
927 Transient Ischaemic Attack 9 0.5 0.5 no signal
928 Feeling Jittery 5 0.5 0.5 no signal
929 Lower Limb Fracture 5 0.5 0.5 no signal
930 Tinnitus 12 0.5 0.5 no signal
931 Disturbance In Attention 14 0.5 0.5 no signal
932 Cellulitis 13 0.5 0.5 no signal
933 Heart Rate Decreased 9 0.5 0.5 no signal
934 Influenza Like Illness 21 0.5 0.5 no signal
935 Respiratory Arrest 7 0.5 0.5 no signal
936 Lactic Acidosis 8 0.5 0.5 no signal
937 Nasopharyngitis 46 0.5 0.5 no signal
938 Pneumonia Aspiration 6 0.4 0.4 no signal
939 Osteonecrosis Of Jaw 6 0.4 0.4 no signal
940 Inappropriate Schedule Of Product Administration 42 0.4 0.4 no signal
941 Lacrimation Increased 7 0.4 0.4 no signal
942 Genital Haemorrhage 3 0.4 0.4 no signal
943 Bronchitis 17 0.4 0.4 no signal
944 Nervous System Disorder 7 0.4 0.4 no signal
945 Pulmonary Oedema 10 0.4 0.4 no signal
946 Lung Neoplasm Malignant 9 0.4 0.4 no signal
947 Upper Respiratory Tract Infection 10 0.4 0.4 no signal
948 Prostatic Specific Antigen Increased 3 0.4 0.4 no signal
949 Hypoacusis 9 0.4 0.4 no signal
950 Dry Eye 10 0.4 0.4 no signal
951 Drug Hypersensitivity 40 0.4 0.4 no signal
952 Eye Pain 11 0.4 0.4 no signal
953 Eczema 10 0.4 0.4 no signal
954 Ill-defined Disorder 12 0.4 0.4 no signal
955 Depression 45 0.4 0.4 no signal
956 Infusion Related Reaction 13 0.4 0.4 no signal
957 Gastric Cancer 5 0.4 0.4 no signal
958 Anaphylactic Shock 5 0.4 0.4 no signal
959 Anxiety 55 0.4 0.3 no signal
960 Haematoma 5 0.3 0.3 no signal
961 Arthritis 15 0.3 0.3 no signal
962 Metabolic Acidosis 6 0.3 0.3 no signal
963 Cataract 11 0.3 0.3 no signal
964 Blood Glucose Increased 35 0.3 0.3 no signal
965 Sinusitis 19 0.3 0.3 no signal
966 Fear 5 0.3 0.3 no signal
967 Mental Disorder 8 0.3 0.3 no signal
968 Eye Disorder 6 0.3 0.3 no signal
969 Lip Swelling 6 0.3 0.3 no signal
970 Nasal Congestion 10 0.3 0.3 no signal
971 Diabetes Mellitus 13 0.3 0.3 no signal
972 Cardiac Arrest 14 0.3 0.3 no signal
973 Road Traffic Accident 7 0.3 0.3 no signal
974 Underdose 12 0.3 0.3 no signal
975 Accidental Overdose 6 0.3 0.3 no signal
976 Drug Effect Incomplete 6 0.3 0.3 no signal
977 Emotional Disorder 5 0.3 0.3 no signal
978 Angioedema 7 0.3 0.3 no signal
979 Hip Fracture 5 0.3 0.3 no signal
980 Condition Aggravated 46 0.3 0.3 no signal
981 Wheezing 9 0.3 0.3 no signal
982 Staphylococcal Infection 5 0.3 0.3 no signal
983 Ocular Hyperaemia 7 0.3 0.3 no signal
984 Weight Increased 33 0.3 0.3 no signal
985 Therapeutic Product Effect Incomplete 10 0.3 0.3 no signal
986 Incorrect Drug Administration Duration 4 0.3 0.3 no signal
987 Wrong Technique In Product Usage Process 28 0.3 0.2 no signal
988 Flushing 14 0.2 0.2 no signal
989 Therapy Interrupted 9 0.2 0.2 no signal
990 Treatment Noncompliance 7 0.2 0.2 no signal
991 Disease Recurrence 6 0.2 0.2 no signal
992 Extra Dose Administered 5 0.2 0.2 no signal
993 Inappropriate Schedule Of Drug Administration 9 0.2 0.2 no signal
994 Agitation 9 0.2 0.2 no signal
995 Convulsion 7 0.2 0.2 no signal
996 Irritability 7 0.2 0.2 no signal
997 Migraine 11 0.2 0.2 no signal
998 Nervousness 6 0.2 0.2 no signal
999 Covid-19 18 0.2 0.2 no signal
1000 Injury 7 0.2 0.2 no signal
1001 Stress 7 0.2 0.2 no signal
1002 Chronic Obstructive Pulmonary Disease 5 0.2 0.2 no signal
1003 Anaphylactic Reaction 5 0.2 0.2 no signal
1004 Medication Error 5 0.2 0.2 no signal
1005 Arthropathy 5 0.2 0.2 no signal
1006 Chronic Kidney Disease 5 0.1 0.1 no signal
1007 Overdose 12 0.1 0.1 no signal
1008 Asthma 5 0.1 0.1 no signal
1009 No Adverse Event 6 0.1 0.1 no signal