OpenPV Signal Explorer
FAERS disproportionality dashboard
Reaction

Palmoplantar Keratoderma reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 711 reports · 61 co-occurring drugs

As of the last recalculation, Palmoplantar Keratoderma appears in 711 FAERS reports alongside 61 co-occurring drug terms. The strongest observed disproportionality signal is FELODIPINE EXTENDED-RELEASE TABLETS (PRR 2,181.6).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Felodipine Extended-Release Tablets3872,181.62,258.8
Felodipine3872,181.52,258.6
Linagliptin3831,331.41,360.1
Amitriptyline Hydrochloride3731,308.11,336.7
Isosorbide Dinitrate3661,129.91,151.6
Isosorbide Mononitrate3741,112.81,133.3
Dapagliflozin389798.2808.2
Esomeprazole377377.7380.0
Cetirizine Hydrochloride Allergy252376.8380.0
Cetirizine Hydrochloride Tablets252376.7379.9
Apixaban389374.6376.8
Candesartan267350.3352.9
Digoxin387345.3347.2
Cetirizine385315.6317.2
Naproxen381304.8306.3
Candesartan Cilexetil152215.0216.2
Esomeprazole Magnesium Capsule, Delayed Release86197.2198.4
Esomeprazole Magnesium Delayed Release Capsules86197.2198.4
Esomeprazole Magnesium Dihydrate86196.4197.6
Levothyroxine Sodium Anhydrous343192.7193.4
Bisoprolol Fumarate396191.3191.9
Hydrochlorothiazide386169.0169.4
Naproxen Sodium383168.9169.4
Cetirizine Hydrochloride384147.1147.4
Lansoprazole393143.2143.5
Cetiirizine146126.7127.2
Losartan334104.6104.8
Esomeprazole Magnesium385103.9104.0
Simvastatin38898.798.9
Fexofenadine4381.081.2
Sotalol Hydrochloride4380.580.7
Bumetanide6477.978.0
Sorafenib4770.971.0
Regorafenib2770.770.9
Omeprazole38670.570.6
Levothyroxine Sodium34661.861.9
Insulin Glargine-Yfgn4361.261.3
Docusate Sodium 100Mg4356.056.1
Omeprazole Magnesium38654.154.2
Doxazosin4347.847.9
Vemurafenib1947.547.6
Fluticasone Propionate Nasal4344.144.2
Sildenafil Powder,4337.637.6
Doxazosin Mesylate4337.037.1
Lactulose4435.735.8
Warfarin Sodium4530.330.3
Senna Leaf2330.130.2
Nitroglycerin4727.427.4
Sennosides 8.6 Mg Tablets1927.227.3
Senna1927.127.1
Losartan Potassium5923.823.8
Citalopram Hydrobromide7723.523.5
Sildenafil4323.123.1
Dabrafenib1521.321.3
Sennosides2121.221.2
Dextrose920.320.3
Dextrose Monohydrate920.020.0
Sitagliptin4519.419.5
Vortioxetine1017.417.4
Encorafenib411.911.9
Salicylic Acid42.22.2

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.