Reaction

Cancer Pain reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 2,534 reports · 143 co-occurring drugs

As of the last recalculation, Cancer Pain appears in 2,534 FAERS reports alongside 143 co-occurring drug terms. The strongest observed disproportionality signal is TRIFLURIDINE AND TIPIRACIL (PRR 27.2).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Trifluridine And Tipiracil	35	27.2	27.2
Fulvestrant	96	24.8	24.8
Bicalutamide	43	23.6	23.6
Cabozantinib	129	23.2	23.2
Regorafenib	32	22.9	23.0
Bupivacaine	23	20.4	20.4
Enzalutamide	120	17.6	17.6
Lenvatinib	67	17.2	17.2
Letrozole Tablets	96	17.0	17.0
Axitinib	39	16.7	16.7
Palbociclib	167	15.3	15.4
Letrozole	110	15.3	15.3
Sorafenib	37	14.8	14.9
Goserelin	24	14.8	14.8
Tranexamic Acid	15	13.9	14.0
Ribociclib	51	13.5	13.5
Ado-Trastuzumab Emtansine	13	12.7	12.7
Prochlorperazine Maleate	14	12.5	12.6
Octreotide Acetate	46	12.5	12.6
Pembrolizumab	150	12.4	12.4
Irinotecan Hydrochloride	19	12.2	12.2
Diphenoxylate Hydrochloride And Atropine Sulfate	20	12.1	12.1
Senna	30	11.8	11.8
Sennosides 8.6 Mg Tablets	29	11.5	11.5
Prochlorperazine	38	11.4	11.4
Zoledronic Acid	54	11.3	11.3
Abemaciclib	27	11.2	11.2
Senna Leaf	31	11.2	11.2
Abiraterone	18	10.9	10.9
Everolimus Tablets	22	10.9	10.9
Magnesium Oxide	54	10.8	10.8
Dexamethasone Sodium Phosphate	13	10.6	10.6
Loperamide Hydrochloride Oral	13	10.5	10.5
Nivolumab	117	10.4	10.4
Sunitinib Malate	48	10.2	10.2
Pemetrexed	26	10.1	10.1
Hyoscyamine Sulfate	11	9.9	9.9
Leuprolide Acetate	90	9.8	9.9
Fam-Trastuzumab Deruxtecan-Nxki	12	9.8	9.8
Morphine	85	9.6	9.7
Pazopanib Hydrochloride	31	9.5	9.5
Fentanyl	109	9.5	9.5
Anastrozole Tablets	24	9.3	9.3
Loperamide Hcl	14	9.0	9.0
Bisacodyl Suppositories	14	8.9	8.9
Everolimus	54	8.9	8.9
Biscodyl	14	8.9	8.9
Abiraterone Acetate	43	8.7	8.7
Standardized Senna Concentrate	13	8.5	8.5
Exemestane	22	8.5	8.5
Oxycodone	181	8.5	8.5
Trimethoprim	12	8.4	8.4
Methocarbamol Tablets	17	8.4	8.4
Methocarbamol	23	8.4	8.4
Sennosides	30	8.3	8.3
Pemetrexed Disodium	38	8.3	8.3
Bisacodyl	14	8.2	8.2
Dronabinol	8	8.2	8.2
Lidocaine Hydrochloride	58	8.1	8.1
Travoprost	8	7.6	7.6
Encorafenib	9	7.5	7.5
Atezolizumab	34	7.3	7.3
Lidocaine Hydrochloride And Epinephrine Bitartrate	46	7.2	7.2
Anastrozole	31	7.0	7.0
Ipilimumab	36	6.9	6.9
Dextrose	11	6.9	6.9
Lutetium Lu 177 Vipivotide Tetraxetan	11	6.9	6.9
Panitumumab	13	6.8	6.9
Dextrose Monohydrate	11	6.8	6.8
Oxycodone Hydrochloride	168	6.7	6.7
Quinine	7	6.7	6.7
Carboplatin	100	6.7	6.7
Miconazole Nitrate	7	6.6	6.6
Ondansetron	85	6.6	6.6
Ondansetron Tablets	85	6.6	6.6
Rucaparib	7	6.5	6.5
Drs. Clotrimazole	9	6.4	6.4
Family Wellness Clotrimazole	9	6.4	6.4
Clotrimazole Topical	9	6.4	6.4
Gefitinib	7	6.4	6.4
Ondansetron Hydrochloride	92	6.4	6.4
Lanreotide Acetate	6	6.3	6.3
Paclitaxel (Aibumin-Bound)	61	6.2	6.2
Oxycodone And Acetaminophen Tablets	9	6.2	6.2
Paclitaxel	72	6.1	6.1
Morphine Sulfate	87	6.1	6.1
Clotrimazole	9	6.0	6.0
Fosaprepitant Dimeglumine	10	6.0	6.0
Loperamide Hydrochloride	31	5.8	5.8
Suvorexant	9	5.7	5.7
Alpelisib	6	5.7	5.7
Metoclopramide Hydrochloride	52	5.6	5.6
Olaparib	14	5.5	5.5
Granisetron Hydrochloride	7	5.5	5.5
Fexofenadine	11	5.5	5.5
Heparin Sodium	9	5.4	5.4
Denosumab	126	5.3	5.3
Docetaxel Anhydrous	43	5.3	5.3
Docetaxel	43	5.3	5.3
Triamcinolone Acetonide Ointment Usp, 0.05%	15	5.3	5.3
Carboxymethylcellulose Sodium	6	5.3	5.3
Capecitabine	55	5.0	5.0
Cetuximab	19	5.0	5.0
Osimertinib	19	4.9	4.9
Niraparib	13	4.8	4.8
Methadone	24	4.6	4.6
Relugolix	13	4.5	4.5
Oxycodone Hydrochloride And Acetaminophen	53	4.5	4.5
Aprepitant	10	4.5	4.5
Hydromorphone Hydrochloride	48	4.3	4.4
Lapatinib	8	4.2	4.2
Trastuzumab	35	4.2	4.2
Polatuzumab Vedotin	5	4.2	4.2
Bevacizumab	62	4.2	4.2
Dexamethasone 1.5 Mg	141	4.1	4.1
Dexamethasone	142	4.1	4.1
Carfilzomib	14	4.1	4.1
Durvalumab	10	4.0	4.1
Pitavastatin Calcium	5	4.0	4.0
Tolvaptan	7	4.0	4.0
Granisetron	5	3.9	3.9
Temozolomide	10	3.9	3.9
Gemcitabine Hydrochloride	25	3.9	3.9
Crizotinib	6	3.9	3.9
Selinexor	4	3.8	3.8
Mometasone Furoate And Formoterol Fumarate Dihydrate	7	3.7	3.7
Oxycodone And Acetaminophen	10	3.5	3.5
Entecavir	5	3.5	3.5
Erlotinib	4	3.4	3.4
Daratumumab	16	3.3	3.3
Cisplatin	31	3.3	3.3
Erlotinib Hydrochloride	5	3.3	3.3
Fentanyl Citrate	7	3.2	3.2
Lenalidomide	154	3.1	3.1
Bortezomib	33	3.1	3.1
Apalutamide	4	2.8	2.8
Vismodegib	3	2.8	2.8
Bosutinib	3	2.7	2.7
Dabrafenib	7	2.7	2.7
Pomalidomide	32	2.6	2.6
Axicabtagene Ciloleucel	3	2.5	2.5
Tapentadol Hydrochloride	8	2.0	2.0
Pegfilgrastim	19	1.6	1.6

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.