OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Vemurafenib

1,000 flagged reaction(s) · 36,765 total co-reports · max PRR 2,307.7
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Radiosensitisation Therapy 4 2,307.7 2,308.4 signal
2 Epidermal Naevus Syndrome 4 1,153.8 1,154.2 signal
3 Neutrophilic Panniculitis 17 535.0 535.7 signal
4 Hairy Cell Leukaemia Recurrent 9 502.5 502.9 signal
5 Keratoacanthoma 105 321.1 323.9 signal
6 Keratosis Pilaris 34 273.7 274.5 signal
7 Liver Palpable 8 223.3 223.5 signal
8 Eccrine Squamous Syringometaplasia 4 216.3 216.4 signal
9 Braf Gene Mutation 9 194.7 194.9 signal
10 Serous Retinopathy 9 165.7 165.8 signal
11 Acanthoma 4 144.2 144.3 signal
12 Solar Dermatitis 20 139.6 139.8 signal
13 Braf V600e Mutation Positive 4 130.6 130.7 signal
14 Panniculitis Lobular 6 123.6 123.7 signal
15 Rash Follicular 10 120.2 120.3 signal
16 Septal Panniculitis 5 115.4 115.4 signal
17 Acantholysis 4 111.7 111.7 signal
18 Papilloma 19 111.5 111.6 signal
19 Skin Papilloma 234 108.6 110.7 signal
20 Cardiac Neoplasm Malignant 4 103.3 103.4 signal
21 Sunburn 373 92.4 95.4 signal
22 Melanosis 5 81.6 81.7 signal
23 Metastatic Malignant Melanoma 102 81.6 82.3 signal
24 Hairy Cell Leukaemia 10 79.4 79.5 signal
25 Serous Retinal Detachment 32 73.6 73.7 signal
26 Intracranial Tumour Haemorrhage 14 66.4 66.5 signal
27 Acrochordon 48 66.2 66.5 signal
28 Hyperkeratosis 192 63.1 64.1 signal
29 Skin Toxicity 176 57.2 58.0 signal
30 Melanocytic Naevus 137 56.6 57.2 signal
31 Gastrointestinal Lymphoma 8 56.3 56.3 signal
32 Transient Acantholytic Dermatosis 9 55.2 55.3 signal
33 Chorioretinopathy 43 54.0 54.2 signal
34 Overgrowth Bacterial 8 53.0 53.1 signal
35 Bacterial Diarrhoea 6 51.7 51.7 signal
36 Sideroblastic Anaemia 4 50.9 50.9 signal
37 Mucocutaneous Rash 4 47.7 47.8 signal
38 Organic Brain Syndrome 5 47.5 47.6 signal
39 Palmoplantar Keratoderma 19 47.5 47.6 signal
40 Melanoma Recurrent 11 47.2 47.3 signal
41 Radiation Skin Injury 30 46.5 46.6 signal
42 Squamous Cell Carcinoma 239 45.6 46.6 signal
43 Milia 9 45.4 45.4 signal
44 Photosensitivity Reaction 414 45.3 46.9 signal
45 Panniculitis 58 43.2 43.4 signal
46 Superficial Spreading Melanoma Stage Unspecified 6 42.4 42.4 signal
47 Autoimmune Colitis 15 41.9 41.9 signal
48 Peripheral Nerve Lesion 7 38.3 38.4 signal
49 Malignant Melanoma Stage Iv 6 37.8 37.8 signal
50 Radiation Necrosis 12 37.8 37.8 signal
51 Benign Neoplasm Of Skin 7 36.9 37.0 signal
52 Epidural Lipomatosis 7 36.0 36.0 signal
53 Squamous Cell Carcinoma Of Skin 120 35.7 36.0 signal
54 Brain Tumour Operation 4 35.3 35.3 signal
55 Metastases To Central Nervous System 244 34.1 34.8 signal
56 Vogt-koyanagi-harada Disease 4 33.3 33.3 signal
57 Acanthosis 6 32.6 32.6 signal
58 Anaplastic Astrocytoma 3 32.1 32.1 signal
59 Relapsing Fever 5 31.4 31.4 signal
60 Enanthema 10 30.9 30.9 signal
61 Mass 237 30.2 30.8 signal
62 Metastases To Gastrointestinal Tract 4 29.5 29.5 signal
63 Photodermatosis 7 29.3 29.3 signal
64 Neutrophilic Dermatosis 6 26.8 26.8 signal
65 Seborrhoeic Keratosis 22 26.7 26.8 signal
66 Malignant Melanoma In Situ 18 25.4 25.4 signal
67 Cutaneous Sarcoidosis 6 25.2 25.2 signal
68 Dermatitis Acneiform 82 24.1 24.3 signal
69 Neoplasm Skin 21 24.0 24.0 signal
70 Scar Pain 5 21.9 21.9 signal
71 Hypercreatinaemia 4 21.6 21.6 signal
72 Recall Phenomenon 10 21.2 21.3 signal
73 Fat Necrosis 7 20.5 20.5 signal
74 Skin Mass 76 20.3 20.4 signal
75 Xerosis 14 20.3 20.3 signal
76 Fibrous Histiocytoma 4 20.0 20.0 signal
77 Dysplastic Naevus 4 19.8 19.8 signal
78 Enterobacter Sepsis 4 19.2 19.2 signal
79 Defaecation Disorder 7 18.6 18.6 signal
80 Ocular Toxicity 11 18.4 18.4 signal
81 Nodal Arrhythmia 9 18.4 18.4 signal
82 Iridocyclitis 32 18.1 18.2 signal
83 Iris Adhesions 5 17.5 17.5 signal
84 Malignant Melanoma 131 17.3 17.5 signal
85 Central Serous Chorioretinopathy 6 17.2 17.2 signal
86 Metastases To Spleen 4 17.0 17.0 signal
87 Actinic Keratosis 25 17.0 17.0 signal
88 Rash Maculo-papular 211 16.9 17.1 signal
89 Limb Mass 20 16.2 16.2 signal
90 Retinopathy 34 16.1 16.2 signal
91 Uveitis 120 15.7 15.9 signal
92 Peripheral Motor Neuropathy 12 15.2 15.2 signal
93 Hypophysitis 17 14.9 15.0 signal
94 Dermal Cyst 20 14.4 14.4 signal
95 Detachment Of Retinal Pigment Epithelium 7 14.2 14.2 signal
96 Erythema Nodosum 28 14.1 14.2 signal
97 Oropharyngeal Candidiasis 7 13.7 13.7 signal
98 Neoplasm 87 13.3 13.4 signal
99 Toxic Skin Eruption 76 13.3 13.4 signal
100 Skin Hypopigmentation 13 13.1 13.1 signal
101 Rash Morbilliform 20 12.7 12.8 signal
102 Pseudolymphoma 4 12.6 12.6 signal
103 Metastases To Meninges 16 12.6 12.6 signal
104 Tumour Haemorrhage 20 12.4 12.4 signal
105 Blood Lactate Dehydrogenase Increased 110 12.2 12.3 signal
106 Alveolar Proteinosis 4 12.1 12.1 signal
107 Lip Ulceration 8 12.1 12.1 signal
108 Erythema Multiforme 62 11.7 11.8 signal
109 Radiation Injury 7 11.6 11.6 signal
110 Disease Progression 768 11.5 12.2 signal
111 Nipple Disorder 4 11.4 11.4 signal
112 Dermatitis Exfoliative Generalised 22 11.3 11.3 signal
113 Metastases To Pelvis 4 11.2 11.2 signal
114 Dermatitis Exfoliative 32 11.2 11.2 signal
115 Drug Reaction With Eosinophilia And Systemic Symptoms 161 11.1 11.3 signal
116 Hepatitis Viral 5 11.0 11.0 signal
117 Magnetic Resonance Imaging Head Abnormal 4 10.9 10.9 signal
118 Peritoneal Disorder 4 10.8 10.8 signal
119 Chronic Myelomonocytic Leukaemia 4 10.6 10.6 signal
120 Mycosis Fungoides 5 10.6 10.6 signal
121 Retinal Detachment 54 10.4 10.4 signal
122 Atrial Tachycardia 12 10.0 10.0 signal
123 Sarcoidosis 27 10.0 10.0 signal
124 Metastasis 40 9.8 9.9 signal
125 Intracranial Mass 5 9.4 9.4 signal
126 Tumour Pain 7 9.3 9.3 signal
127 Brain Stem Haemorrhage 5 9.2 9.2 signal
128 Squamous Cell Carcinoma Of Lung 4 9.2 9.2 signal
129 Metastases To Peritoneum 13 9.1 9.2 signal
130 Small Intestinal Haemorrhage 10 8.8 8.8 signal
131 Monoparesis 9 8.7 8.7 signal
132 Neurological Decompensation 11 8.5 8.5 signal
133 Rash Generalised 127 8.5 8.6 signal
134 Brain Neoplasm 43 8.2 8.3 signal
135 Transitional Cell Carcinoma 6 8.1 8.1 signal
136 Bone Neoplasm 5 8.1 8.1 signal
137 Rash Pustular 33 7.9 8.0 signal
138 Electrocardiogram Qt Prolonged 162 7.9 8.0 signal
139 Cholangitis Sclerosing 9 7.7 7.7 signal
140 Renal Function Test Abnormal 20 7.7 7.7 signal
141 Adenocarcinoma Gastric 4 7.6 7.7 signal
142 Vitiligo 10 7.6 7.6 signal
143 Lipase Increased 33 7.6 7.6 signal
144 Cystoid Macular Oedema 8 7.6 7.6 signal
145 Lymphadenopathy Mediastinal 8 7.4 7.4 signal
146 Alveolitis 6 7.4 7.4 signal
147 Electrocardiogram Change 4 7.4 7.4 signal
148 Hepatotoxicity 92 7.3 7.4 signal
149 Skin Reaction 58 7.3 7.3 signal
150 Neuroendocrine Carcinoma Of The Skin 4 7.2 7.2 signal
151 Thermal Burn 29 7.2 7.2 signal
152 Immune-mediated Hepatitis 8 7.2 7.2 signal
153 Mucosal Dryness 8 7.0 7.1 signal
154 Brain Operation 9 7.0 7.0 signal
155 Astigmatism 6 7.0 7.0 signal
156 Blood Bilirubin Abnormal 5 6.9 6.9 signal
157 Nipple Pain 8 6.9 6.9 signal
158 Paraparesis 7 6.9 6.9 signal
159 Metastases To Skin 4 6.9 6.9 signal
160 Adenocarcinoma Pancreas 5 6.8 6.8 signal
161 Lymphangiosis Carcinomatosa 4 6.8 6.8 signal
162 Amylase Increased 14 6.7 6.7 signal
163 Ejection Fraction Decreased 59 6.7 6.7 signal
164 Protein Total Increased 10 6.6 6.6 signal
165 Adenocarcinoma Of Colon 7 6.6 6.6 signal
166 Cholestatic Liver Injury 8 6.6 6.6 signal
167 Guillain-barre Syndrome 18 6.6 6.6 signal
168 Hepatocellular Injury 53 6.6 6.6 signal
169 Piloerection 4 6.5 6.5 signal
170 Lip Blister 10 6.5 6.5 signal
171 Acne Pustular 3 6.4 6.4 signal
172 Oral Fungal Infection 10 6.4 6.4 signal
173 Generalised Erythema 21 6.4 6.4 signal
174 Stevens-johnson Syndrome 81 6.4 6.4 signal
175 Skin Hypertrophy 10 6.3 6.3 signal
176 Rash 1,547 6.3 7.1 signal
177 Palmar-plantar Erythrodysaesthesia Syndrome 81 6.1 6.1 signal
178 Drug Eruption 61 6.1 6.1 signal
179 Fat Tissue Increased 5 6.1 6.1 signal
180 Abdominal Neoplasm 3 5.9 5.9 signal
181 Decreased Activity 36 5.9 5.9 signal
182 Cholestasis 64 5.9 5.9 signal
183 Nephritis 11 5.8 5.9 signal
184 Hypertrichosis 6 5.7 5.7 signal
185 Retinal Oedema 6 5.6 5.6 signal
186 Erysipelas 16 5.6 5.6 signal
187 Retinal Vein Occlusion 9 5.6 5.6 signal
188 Blood Creatine Phosphokinase Increased 92 5.5 5.6 signal
189 Face Oedema 53 5.5 5.5 signal
190 Gamma-glutamyltransferase Increased 68 5.4 5.4 signal
191 Lymphopenia 43 5.4 5.4 signal
192 Seborrhoeic Dermatitis 5 5.4 5.4 signal
193 Oropharyngeal Blistering 5 5.3 5.3 signal
194 Hyperaemia 6 5.3 5.3 signal
195 Metastatic Neoplasm 13 5.3 5.3 signal
196 Cardioactive Drug Level Increased 4 5.3 5.3 signal
197 Hyperthyroidism 43 5.2 5.2 signal
198 Blood Bilirubin Increased 80 5.2 5.2 signal
199 Skin Depigmentation 4 5.2 5.2 signal
200 Intentional Product Use Issue 257 5.1 5.2 signal
201 Kidney Fibrosis 5 5.1 5.1 signal
202 Macule 8 5.1 5.1 signal
203 Prerenal Failure 4 5.0 5.0 signal
204 Macular Oedema 16 5.0 5.0 signal
205 Blister 160 5.0 5.1 signal
206 Alopecia 561 5.0 5.2 signal
207 Metastases To Lymph Nodes 19 5.0 5.0 signal
208 Blood Alkaline Phosphatase Increased 69 4.9 4.9 signal
209 Pancreatic Enzymes Increased 4 4.8 4.8 signal
210 Eosinophilia 48 4.8 4.8 signal
211 Peripheral Sensory Neuropathy 16 4.8 4.8 signal
212 Subcutaneous Abscess 13 4.8 4.8 signal
213 Gingival Hypertrophy 4 4.7 4.7 signal
214 Papilloedema 12 4.7 4.7 signal
215 Hyperthermia 20 4.7 4.7 signal
216 Basal Cell Carcinoma 41 4.6 4.6 signal
217 Folliculitis 27 4.6 4.6 signal
218 Acute Febrile Neutrophilic Dermatosis 6 4.6 4.6 signal
219 Facial Paralysis 22 4.6 4.6 signal
220 Toxic Epidermal Necrolysis 39 4.5 4.6 signal
221 Mucosal Inflammation 67 4.5 4.5 signal
222 Cardiac Tamponade 12 4.4 4.4 signal
223 Pneumonia Viral 8 4.4 4.4 signal
224 Hypercholesterolaemia 24 4.4 4.4 signal
225 Arthralgia 1,039 4.4 4.7 signal
226 Purpura 22 4.4 4.4 signal
227 Neck Mass 7 4.4 4.4 signal
228 Acute Leukaemia 4 4.3 4.3 signal
229 Lymphoedema 17 4.3 4.3 signal
230 Skin Lesion 67 4.3 4.3 signal
231 Poor Quality Sleep 52 4.3 4.3 signal
232 Metastases To Lung 28 4.3 4.3 signal
233 Hyperpyrexia 10 4.2 4.2 signal
234 Diverticular Perforation 5 4.2 4.2 signal
235 Transaminases Increased 53 4.2 4.2 signal
236 Brain Oedema 30 4.2 4.2 signal
237 Systemic Inflammatory Response Syndrome 9 4.2 4.2 signal
238 Leukaemia Recurrent 4 4.2 4.2 signal
239 Dermatitis 49 4.2 4.2 signal
240 Dermatitis Bullous 17 4.2 4.2 signal
241 Staphylococcus Test Positive 5 4.1 4.1 signal
242 Hyperbilirubinaemia 24 4.1 4.1 signal
243 Papillary Thyroid Cancer 4 4.1 4.1 signal
244 Dysaesthesia 7 4.1 4.1 signal
245 Hepatitis 59 4.1 4.1 signal
246 Iritis 7 4.0 4.0 signal
247 Decreased Appetite 532 4.0 4.2 signal
248 Viith Nerve Paralysis 8 4.0 4.0 signal
249 Burns Second Degree 4 4.0 4.0 signal
250 Distributive Shock 5 4.0 4.0 signal
251 Facial Paresis 8 4.0 4.0 signal
252 Induration 4 3.9 3.9 signal
253 Paresis 5 3.9 3.9 signal
254 Rash Papular 50 3.9 3.9 signal
255 Dysgeusia 166 3.9 3.9 signal
256 Soft Tissue Infection 4 3.9 3.9 signal
257 Venous Occlusion 4 3.8 3.8 signal
258 Pneumonitis 59 3.8 3.8 signal
259 Hyperaesthesia 18 3.8 3.8 signal
260 Liver Abscess 7 3.8 3.8 signal
261 Dysphagia 204 3.8 3.8 signal
262 Oral Candidiasis 28 3.8 3.8 signal
263 Impaired Work Ability 46 3.8 3.8 signal
264 Pyrexia 742 3.8 4.0 signal
265 Blood Creatinine Increased 139 3.7 3.8 signal
266 Gastrointestinal Toxicity 10 3.7 3.7 signal
267 Myopia 5 3.7 3.7 signal
268 Lung Neoplasm 9 3.7 3.7 signal
269 Myalgia 355 3.7 3.8 signal
270 Metastases To Spine 7 3.7 3.7 signal
271 Behaviour Disorder 11 3.6 3.6 signal
272 Glomerulonephritis 5 3.6 3.6 signal
273 Blepharitis 8 3.6 3.6 signal
274 Furuncle 16 3.6 3.6 signal
275 Cell Death 4 3.5 3.5 signal
276 Neoplasm Progression 70 3.5 3.5 signal
277 Keratitis 6 3.5 3.5 signal
278 No Adverse Event 346 3.4 3.5 signal
279 Left Ventricular Dysfunction 13 3.4 3.4 signal
280 Bundle Branch Block Right 9 3.4 3.4 signal
281 Cardiotoxicity 17 3.4 3.4 signal
282 Hypertransaminasaemia 13 3.4 3.4 signal
283 Alanine Aminotransferase Abnormal 4 3.3 3.4 signal
284 Exfoliative Rash 5 3.3 3.3 signal
285 Hypophosphataemia 14 3.3 3.4 signal
286 Hepatitis Toxic 5 3.3 3.3 signal
287 Impaired Self-care 4 3.3 3.3 signal
288 Rash Erythematous 89 3.3 3.4 signal
289 Vasculitis 22 3.3 3.3 signal
290 Hypertriglyceridaemia 11 3.3 3.3 signal
291 Skin Infection 21 3.3 3.3 signal
292 Autoimmune Hepatitis 13 3.3 3.3 signal
293 Oral Mucosal Blistering 12 3.3 3.3 signal
294 Aspartate Aminotransferase Increased 99 3.3 3.3 signal
295 Skin Disorder 62 3.3 3.3 signal
296 Vitreous Detachment 4 3.3 3.3 signal
297 Paronychia 8 3.2 3.2 signal
298 Cerebellar Syndrome 4 3.2 3.2 no signal
299 Pleuritic Pain 5 3.2 3.2 signal
300 Pericarditis 30 3.2 3.2 signal
301 Tongue Blistering 4 3.1 3.1 no signal
302 Adenocarcinoma 4 3.1 3.1 no signal
303 Brain Neoplasm Malignant 8 3.1 3.1 signal
304 Lichenoid Keratosis 4 3.1 3.1 no signal
305 Skin Cancer 38 3.1 3.1 signal
306 Blood Creatinine Abnormal 6 3.1 3.1 signal
307 Amyloidosis 3 3.1 3.1 no signal
308 Periorbital Oedema 9 3.0 3.0 signal
309 Cerebral Ischaemia 9 3.0 3.0 signal
310 Gastritis Erosive 8 3.0 3.0 signal
311 Alopecia Areata 3 3.0 3.0 no signal
312 Hyperuricaemia 7 3.0 3.0 signal
313 Hypokalaemia 78 3.0 3.0 signal
314 Local Swelling 30 3.0 3.0 signal
315 Aphthous Ulcer 13 3.0 3.0 signal
316 Conjunctivitis 31 3.0 3.0 signal
317 Thyroiditis 5 2.9 2.9 signal
318 Atypical Pneumonia 5 2.9 2.9 signal
319 Alanine Aminotransferase Increased 103 2.9 3.0 signal
320 Scab 19 2.9 2.9 signal
321 Renal Failure Acute 72 2.9 3.0 signal
322 Rash Vesicular 8 2.9 2.9 signal
323 Haemophagocytic Lymphohistiocytosis 12 2.9 2.9 signal
324 Lymphadenitis 4 2.9 2.9 no signal
325 Pericardial Effusion 38 2.9 2.9 signal
326 Skin Exfoliation 137 2.9 2.9 signal
327 Liver Function Test Abnormal 48 2.9 2.9 signal
328 Hepatic Pain 7 2.9 2.9 signal
329 Retinal Tear 4 2.9 2.9 no signal
330 Urosepsis 15 2.9 2.9 signal
331 Cholangitis 10 2.8 2.9 signal
332 Nephropathy Toxic 18 2.8 2.8 signal
333 Intracranial Pressure Increased 9 2.8 2.8 signal
334 Body Temperature Increased 33 2.8 2.8 signal
335 Hypoalbuminaemia 12 2.8 2.8 signal
336 Adrenal Disorder 3 2.7 2.7 no signal
337 Malignant Neoplasm Progression 159 2.7 2.8 signal
338 Myositis 14 2.7 2.7 signal
339 Benign Prostatic Hyperplasia 8 2.7 2.7 signal
340 Nodule 20 2.7 2.7 signal
341 Erythema 312 2.7 2.7 signal
342 Yellow Skin 7 2.6 2.6 signal
343 Cerebral Haematoma 5 2.6 2.6 no signal
344 Anal Abscess 8 2.6 2.6 signal
345 Cerebral Haemorrhage 53 2.6 2.6 signal
346 Cheilitis 8 2.6 2.6 signal
347 Neoplasm Recurrence 5 2.6 2.6 no signal
348 Hepatic Enzyme Increased 100 2.6 2.6 signal
349 Gastric Perforation 4 2.6 2.6 no signal
350 Liver Function Test Increased 31 2.6 2.6 signal
351 Cyst 18 2.5 2.5 signal
352 Dermatitis Allergic 18 2.5 2.5 signal
353 Vitreous Haemorrhage 4 2.5 2.5 no signal
354 Papule 10 2.5 2.5 signal
355 Pancreatitis Acute 32 2.5 2.5 signal
356 Anal Haemorrhage 4 2.5 2.5 no signal
357 Proctitis 4 2.5 2.5 no signal
358 Metastases To Liver 25 2.5 2.5 signal
359 Renal Tubular Disorder 4 2.5 2.5 no signal
360 Jaundice Cholestatic 5 2.5 2.5 no signal
361 Neurological Symptom 8 2.5 2.5 signal
362 Hair Texture Abnormal 19 2.5 2.5 signal
363 Colitis 53 2.5 2.5 signal
364 Maculopathy 5 2.5 2.5 no signal
365 Ageusia 35 2.5 2.5 signal
366 Torsade De Pointes 11 2.5 2.5 signal
367 Blood Uric Acid Increased 8 2.4 2.4 signal
368 Stress Cardiomyopathy 8 2.4 2.4 signal
369 Cerebral Disorder 10 2.4 2.4 signal
370 Meningitis Aseptic 6 2.4 2.4 no signal
371 Dehydration 178 2.3 2.4 signal
372 Fatigue 1,033 2.3 2.5 signal
373 Myocarditis 15 2.3 2.3 signal
374 Pancreatitis 70 2.3 2.3 signal
375 Acute Coronary Syndrome 11 2.3 2.3 signal
376 Encephalitis 9 2.3 2.3 signal
377 Lymphocyte Count Decreased 23 2.3 2.3 signal
378 Pigmentation Disorder 8 2.3 2.3 signal
379 Localised Oedema 6 2.3 2.3 no signal
380 Acne 98 2.3 2.3 signal
381 Drug Resistance 33 2.3 2.3 signal
382 Performance Status Decreased 6 2.3 2.3 no signal
383 Diarrhoea 825 2.3 2.3 signal
384 Spinal Cord Compression 5 2.2 2.2 no signal
385 Nail Discolouration 5 2.2 2.2 no signal
386 Duodenal Ulcer 9 2.2 2.2 signal
387 Swelling 119 2.2 2.3 signal
388 Electrocardiogram Abnormal 10 2.2 2.2 signal
389 Photopsia 8 2.2 2.2 signal
390 Renal Failure 169 2.2 2.2 signal
391 Swelling Face 82 2.2 2.2 signal
392 Heart Rate Abnormal 7 2.2 2.2 no signal
393 Cytokine Release Syndrome 24 2.2 2.2 signal
394 Intestinal Perforation 14 2.2 2.2 signal
395 Spinal Osteoarthritis 11 2.2 2.2 signal
396 General Physical Health Deterioration 143 2.2 2.2 signal
397 Agranulocytosis 23 2.2 2.2 signal
398 Rash Pruritic 67 2.2 2.2 signal
399 Ocular Hyperaemia 58 2.2 2.2 signal
400 Hepatic Function Abnormal 46 2.2 2.2 signal
401 Skin Ulcer 32 2.2 2.2 signal
402 Mouth Ulceration 26 2.2 2.2 signal
403 Death 1,062 2.2 2.3 signal
404 Hepatic Neoplasm 4 2.2 2.2 no signal
405 Hyperglycaemia 44 2.1 2.1 signal
406 Anaemia 231 2.1 2.1 signal
407 Hepatic Enzyme Abnormal 6 2.1 2.1 no signal
408 Leukopenia 60 2.1 2.1 signal
409 Acute Kidney Injury 180 2.1 2.1 signal
410 Dry Skin 155 2.1 2.1 signal
411 Lip Oedema 5 2.1 2.1 no signal
412 Left Ventricular Failure 4 2.1 2.1 no signal
413 Stomatitis 71 2.1 2.1 signal
414 Pustular Psoriasis 4 2.0 2.0 no signal
415 Hyponatraemia 65 2.0 2.0 signal
416 Granuloma 4 2.0 2.0 no signal
417 Cardiomyopathy 17 2.0 2.0 signal
418 Polyarthritis 6 2.0 2.0 no signal
419 Rhabdomyolysis 47 2.0 2.0 no signal
420 Atrial Flutter 9 2.0 2.0 no signal
421 Fibrin D Dimer Increased 4 2.0 2.0 no signal
422 Conjunctival Hyperaemia 4 2.0 2.0 no signal
423 Cutaneous Vasculitis 4 2.0 2.0 no signal
424 Vision Blurred 153 2.0 2.0 no signal
425 Nervous System Disorder 35 2.0 2.0 no signal
426 Proteinuria 21 2.0 2.0 no signal
427 Liver Disorder 49 1.9 1.9 no signal
428 Asthenopia 6 1.9 1.9 no signal
429 Oesophagitis 12 1.9 1.9 no signal
430 Ventricular Arrhythmia 4 1.9 1.9 no signal
431 Polyneuropathy 13 1.9 1.9 no signal
432 Oedema 59 1.9 1.9 no signal
433 Photophobia 20 1.9 1.9 no signal
434 Intercepted Medication Error 5 1.9 1.9 no signal
435 Colitis Microscopic 5 1.9 1.9 no signal
436 Autoimmune Thyroiditis 4 1.9 1.9 no signal
437 Eye Inflammation 10 1.9 1.9 no signal
438 Visual Impairment 130 1.9 1.9 no signal
439 Chills 123 1.8 1.8 no signal
440 Supraventricular Tachycardia 10 1.8 1.8 no signal
441 C-reactive Protein Increased 38 1.8 1.8 no signal
442 Hypertonia 6 1.8 1.8 no signal
443 Tumour Lysis Syndrome 9 1.8 1.8 no signal
444 Pruritus 389 1.8 1.8 no signal
445 Nausea 811 1.8 1.9 no signal
446 Gastritis 27 1.8 1.8 no signal
447 Spinal Pain 12 1.8 1.8 no signal
448 Skin Odour Abnormal 4 1.8 1.8 no signal
449 Epilepsy 31 1.8 1.8 no signal
450 Odynophagia 6 1.8 1.8 no signal
451 Oesophageal Candidiasis 4 1.8 1.8 no signal
452 Vomiting 474 1.8 1.8 no signal
453 Cholecystitis 12 1.8 1.8 no signal
454 Cardiac Failure 81 1.8 1.8 no signal
455 Drug-induced Liver Injury 31 1.8 1.8 no signal
456 Pneumocystis Jirovecii Pneumonia 10 1.8 1.8 no signal
457 Haemorrhage Intracranial 15 1.8 1.8 no signal
458 Off Label Use 866 1.8 1.8 no signal
459 Hemiparesis 17 1.8 1.8 no signal
460 Peripheral Swelling 153 1.8 1.8 no signal
461 Acne Cystic 3 1.7 1.7 no signal
462 Activated Partial Thromboplastin Time Prolonged 5 1.7 1.7 no signal
463 Hiccups 8 1.7 1.7 no signal
464 Skin Discolouration 45 1.7 1.7 no signal
465 Laryngeal Oedema 6 1.7 1.7 no signal
466 Generalised Oedema 12 1.7 1.7 no signal
467 Chromaturia 22 1.7 1.7 no signal
468 Eosinophil Count Increased 8 1.7 1.7 no signal
469 Neutrophil Count Decreased 39 1.7 1.7 no signal
470 Embolism 8 1.7 1.7 no signal
471 Hordeolum 4 1.7 1.7 no signal
472 Central Nervous System Lesion 13 1.7 1.7 no signal
473 Eyelid Oedema 11 1.6 1.7 no signal
474 Bacteraemia 11 1.6 1.6 no signal
475 Skin Hyperpigmentation 8 1.6 1.6 no signal
476 Lymphadenopathy 33 1.6 1.6 no signal
477 Therapy Partial Responder 14 1.6 1.6 no signal
478 Asthenia 348 1.6 1.6 no signal
479 Ocular Icterus 4 1.6 1.6 no signal
480 Hydrocephalus 5 1.6 1.6 no signal
481 Renal Tubular Necrosis 9 1.6 1.6 no signal
482 Angioedema 40 1.6 1.6 no signal
483 Ventricular Tachycardia 15 1.6 1.6 no signal
484 Adverse Reaction 12 1.6 1.6 no signal
485 Blood Creatine Increased 4 1.6 1.6 no signal
486 Iron Deficiency 4 1.6 1.6 no signal
487 Candida Infection 15 1.6 1.6 no signal
488 Visual Acuity Reduced 30 1.6 1.6 no signal
489 Hypertensive Crisis 10 1.6 1.6 no signal
490 Necrosis 5 1.6 1.6 no signal
491 Hepatic Failure 27 1.6 1.6 no signal
492 Atrial Fibrillation 87 1.6 1.6 no signal
493 Hypercalcaemia 11 1.6 1.6 no signal
494 Urinary Tract Disorder 4 1.6 1.6 no signal
495 Blood Disorder 7 1.5 1.5 no signal
496 Sensory Loss 7 1.5 1.5 no signal
497 Hair Growth Abnormal 6 1.5 1.5 no signal
498 Ischaemia 4 1.5 1.5 no signal
499 Large Intestine Perforation 6 1.5 1.5 no signal
500 Rash Macular 30 1.5 1.5 no signal
501 Sepsis 96 1.5 1.5 no signal
502 Extrasystoles 6 1.5 1.5 no signal
503 Thrombocytopenia 95 1.5 1.5 no signal
504 Disseminated Intravascular Coagulation 12 1.5 1.5 no signal
505 Leukaemia 8 1.5 1.5 no signal
506 Second Primary Malignancy 7 1.5 1.5 no signal
507 Posterior Reversible Encephalopathy Syndrome 8 1.5 1.5 no signal
508 Chronic Lymphocytic Leukaemia 4 1.5 1.5 no signal
509 Abasia 21 1.5 1.5 no signal
510 Hepatitis Cholestatic 5 1.5 1.5 no signal
511 Constipation 180 1.5 1.5 no signal
512 Visual Field Defect 6 1.5 1.5 no signal
513 Tumour Marker Increased 4 1.5 1.5 no signal
514 Enterococcal Infection 4 1.4 1.4 no signal
515 Neutropenia 111 1.4 1.4 no signal
516 Joint Swelling 98 1.4 1.4 no signal
517 Hydronephrosis 6 1.4 1.4 no signal
518 Tubulointerstitial Nephritis 15 1.4 1.4 no signal
519 Multi-organ Failure 14 1.4 1.4 no signal
520 Groin Pain 7 1.4 1.4 no signal
521 Oedema Peripheral 97 1.4 1.4 no signal
522 Renal Impairment 66 1.4 1.4 no signal
523 Electrolyte Imbalance 9 1.4 1.4 no signal
524 Cachexia 4 1.4 1.4 no signal
525 Neoplasm Malignant 52 1.4 1.4 no signal
526 Jaundice 21 1.4 1.4 no signal
527 Partial Seizures 4 1.4 1.4 no signal
528 Haemolysis 6 1.4 1.4 no signal
529 Weight Decreased 215 1.4 1.4 no signal
530 Madarosis 9 1.3 1.3 no signal
531 Failure To Thrive 4 1.3 1.3 no signal
532 Gastroenteritis 11 1.3 1.3 no signal
533 Adrenal Insufficiency 9 1.3 1.3 no signal
534 Hyperlipidaemia 9 1.3 1.3 no signal
535 Bronchiectasis 5 1.3 1.3 no signal
536 Meningitis 5 1.3 1.3 no signal
537 Ascites 22 1.3 1.3 no signal
538 Gingivitis 4 1.3 1.3 no signal
539 Pleural Effusion 45 1.3 1.3 no signal
540 Lacrimation Increased 22 1.3 1.3 no signal
541 General Physical Condition Abnormal 5 1.3 1.3 no signal
542 Metastases To Bone 12 1.3 1.3 no signal
543 Small Intestinal Obstruction 9 1.3 1.3 no signal
544 Pulmonary Thrombosis 8 1.3 1.3 no signal
545 Gingival Bleeding 10 1.3 1.3 no signal
546 Eye Swelling 27 1.3 1.3 no signal
547 Aphasia 22 1.3 1.3 no signal
548 Leukocytosis 13 1.3 1.3 no signal
549 Vitreous Floaters 7 1.3 1.3 no signal
550 Hair Colour Changes 9 1.3 1.3 no signal
551 Acute Pulmonary Oedema 4 1.2 1.2 no signal
552 Febrile Neutropenia 47 1.2 1.2 no signal
553 Angiopathy 4 1.2 1.2 no signal
554 Vertigo 43 1.2 1.2 no signal
555 Pain Of Skin 19 1.2 1.2 no signal
556 Eating Disorder 15 1.2 1.2 no signal
557 Blood Potassium Decreased 21 1.2 1.2 no signal
558 Myocardial Ischaemia 8 1.2 1.2 no signal
559 Pyelonephritis 6 1.2 1.2 no signal
560 Pain In Extremity 205 1.2 1.2 no signal
561 Encephalopathy 17 1.2 1.2 no signal
562 Arrhythmia 33 1.2 1.2 no signal
563 Herpes Virus Infection 4 1.2 1.2 no signal
564 Myopathy 6 1.2 1.2 no signal
565 Motor Dysfunction 7 1.2 1.2 no signal
566 Ulcer 11 1.2 1.2 no signal
567 Neuropathy Peripheral 65 1.2 1.2 no signal
568 Hypovolaemia 4 1.2 1.2 no signal
569 Mouth Haemorrhage 5 1.2 1.2 no signal
570 Oral Disorder 5 1.2 1.2 no signal
571 Haemoptysis 19 1.2 1.2 no signal
572 Ventricular Extrasystoles 7 1.2 1.2 no signal
573 Haematuria 23 1.2 1.2 no signal
574 Lip Dry 6 1.2 1.2 no signal
575 Lip Swelling 22 1.2 1.2 no signal
576 Tendon Pain 5 1.2 1.2 no signal
577 Burning Sensation 46 1.2 1.2 no signal
578 Aortic Aneurysm 5 1.1 1.1 no signal
579 Acute Generalised Exanthematous Pustulosis 5 1.1 1.1 no signal
580 Ill-defined Disorder 39 1.1 1.1 no signal
581 Renal Failure Chronic 5 1.1 1.1 no signal
582 Intestinal Obstruction 24 1.1 1.1 no signal
583 Disorientation 25 1.1 1.1 no signal
584 Hypothyroidism 20 1.1 1.1 no signal
585 Musculoskeletal Pain 33 1.1 1.1 no signal
586 Therapy Change 6 1.1 1.1 no signal
587 Convulsion 36 1.1 1.1 no signal
588 Liver Injury 15 1.1 1.1 no signal
589 Status Epilepticus 7 1.1 1.1 no signal
590 Incoherent 4 1.1 1.1 no signal
591 Aphagia 3 1.1 1.1 no signal
592 Bone Pain 36 1.1 1.1 no signal
593 Hepatomegaly 6 1.1 1.1 no signal
594 Feeding Disorder 12 1.1 1.1 no signal
595 Cardiac Failure Acute 4 1.1 1.1 no signal
596 Hemiplegia 5 1.1 1.1 no signal
597 Taste Disorder 12 1.1 1.1 no signal
598 Joint Range Of Motion Decreased 8 1.1 1.1 no signal
599 Brain Injury 6 1.0 1.0 no signal
600 Postoperative Wound Infection 4 1.0 1.0 no signal
601 Hypophagia 15 1.0 1.0 no signal
602 Hepatic Steatosis 11 1.0 1.0 no signal
603 Ulcer Haemorrhage 4 1.0 1.0 no signal
604 Pseudomonas Infection 5 1.0 1.0 no signal
605 Muscular Weakness 67 1.0 1.0 no signal
606 Pneumonia 190 1.0 1.0 no signal
607 Skin Swelling 5 1.0 1.0 no signal
608 Ear Discomfort 6 1.0 1.0 no signal
609 Musculoskeletal Chest Pain 9 1.0 1.0 no signal
610 Eye Pain 32 1.0 1.0 no signal
611 Joint Effusion 4 1.0 1.0 no signal
612 Dry Eye 28 1.0 1.0 no signal
613 Nail Disorder 5 1.0 1.0 no signal
614 Cellulitis 29 1.0 1.0 no signal
615 Acute Myocardial Infarction 17 1.0 1.0 no signal
616 Formication 4 1.0 1.0 no signal
617 Multiple Organ Dysfunction Syndrome 16 1.0 1.0 no signal
618 Deafness 15 1.0 1.0 no signal
619 Lung Infection 9 1.0 1.0 no signal
620 Pulmonary Toxicity 4 1.0 1.0 no signal
621 Oral Herpes 11 1.0 1.0 no signal
622 Flatulence 32 1.0 1.0 no signal
623 Dysarthria 21 1.0 1.0 no signal
624 Haemolytic Anaemia 5 1.0 1.0 no signal
625 Uterine Leiomyoma 4 1.0 1.0 no signal
626 Blindness 22 0.9 0.9 no signal
627 Headache 338 0.9 0.9 no signal
628 Pemphigoid 4 0.9 0.9 no signal
629 Mental Status Changes 15 0.9 0.9 no signal
630 Lower Gastrointestinal Haemorrhage 4 0.9 0.9 no signal
631 Eye Infection 6 0.9 0.9 no signal
632 Personality Change 5 0.9 0.9 no signal
633 Diarrhoea Haemorrhagic 5 0.9 0.9 no signal
634 Joint Stiffness 14 0.9 0.9 no signal
635 Bedridden 7 0.9 0.9 no signal
636 Septic Shock 23 0.9 0.9 no signal
637 Blood Sodium Decreased 10 0.9 0.9 no signal
638 Parosmia 4 0.9 0.9 no signal
639 Drug Effect Decreased 29 0.9 0.9 no signal
640 Urticaria 87 0.9 0.9 no signal
641 Acidosis 4 0.9 0.9 no signal
642 Pancytopenia 29 0.9 0.9 no signal
643 Eye Disorder 17 0.9 0.9 no signal
644 Dry Mouth 42 0.9 0.9 no signal
645 Neurotoxicity 9 0.9 0.9 no signal
646 Tachycardia 46 0.9 0.9 no signal
647 Interstitial Lung Disease 25 0.9 0.9 no signal
648 Pharyngeal Oedema 8 0.9 0.9 no signal
649 Blood Iron Decreased 6 0.9 0.9 no signal
650 Haemorrhagic Stroke 4 0.9 0.9 no signal
651 Haematochezia 28 0.9 0.9 no signal
652 Oropharyngeal Pain 47 0.9 0.9 no signal
653 White Blood Cell Count Decreased 55 0.9 0.9 no signal
654 Confusional State 82 0.9 0.9 no signal
655 Dyspnoea Exertional 19 0.9 0.9 no signal
656 Hypomagnesaemia 7 0.9 0.9 no signal
657 Ataxia 6 0.9 0.9 no signal
658 Gingival Pain 4 0.9 0.9 no signal
659 Gout 9 0.9 0.9 no signal
660 Diplopia 13 0.9 0.9 no signal
661 Infection 72 0.9 0.9 no signal
662 Glomerular Filtration Rate Decreased 6 0.9 0.9 no signal
663 Neuralgia 12 0.9 0.9 no signal
664 Pulmonary Embolism 47 0.9 0.9 no signal
665 Escherichia Infection 4 0.9 0.9 no signal
666 Cataract 29 0.9 0.9 no signal
667 Myelodysplastic Syndrome 7 0.8 0.8 no signal
668 Petechiae 5 0.8 0.8 no signal
669 Hypocalcaemia 9 0.8 0.8 no signal
670 Blood Urea Increased 8 0.8 0.8 no signal
671 Gastric Ulcer 9 0.8 0.8 no signal
672 Clostridium Difficile Colitis 5 0.8 0.8 no signal
673 Lung Disorder 23 0.8 0.8 no signal
674 Platelet Count Decreased 50 0.8 0.8 no signal
675 Sudden Death 5 0.8 0.8 no signal
676 Inflammation 24 0.8 0.8 no signal
677 Respiratory Failure 34 0.8 0.8 no signal
678 Hypoaesthesia Oral 7 0.8 0.8 no signal
679 Aspiration 5 0.8 0.8 no signal
680 Appetite Disorder 3 0.8 0.8 no signal
681 Urine Output Decreased 4 0.8 0.8 no signal
682 Intervertebral Disc Protrusion 10 0.8 0.8 no signal
683 Blood Calcium Increased 4 0.8 0.8 no signal
684 Hypersomnia 13 0.8 0.8 no signal
685 Drug Interaction 72 0.8 0.8 no signal
686 Melaena 10 0.8 0.8 no signal
687 Therapy Cessation 23 0.8 0.8 no signal
688 Eye Haemorrhage 6 0.8 0.8 no signal
689 Drug Intolerance 43 0.8 0.8 no signal
690 Sciatica 7 0.8 0.8 no signal
691 Micturition Urgency 5 0.8 0.8 no signal
692 Heart Rate Irregular 10 0.8 0.8 no signal
693 Syncope 44 0.8 0.8 no signal
694 Hypertension 93 0.8 0.8 no signal
695 Optic Neuritis 4 0.8 0.8 no signal
696 Iron Deficiency Anaemia 4 0.8 0.8 no signal
697 Abdominal Pain 101 0.8 0.8 no signal
698 Ovarian Cancer 4 0.8 0.8 no signal
699 Appendicitis 4 0.8 0.8 no signal
700 Sinus Tachycardia 6 0.7 0.7 no signal
701 Retching 9 0.7 0.7 no signal
702 Covid-19 Pneumonia 5 0.7 0.7 no signal
703 Speech Disorder 22 0.7 0.7 no signal
704 Arthritis 33 0.7 0.7 no signal
705 Cytopenia 5 0.7 0.7 no signal
706 Autoimmune Disorder 4 0.7 0.7 no signal
707 Herpes Zoster 24 0.7 0.7 no signal
708 Upper Gastrointestinal Haemorrhage 7 0.7 0.7 no signal
709 Atelectasis 4 0.7 0.7 no signal
710 Myelosuppression 14 0.7 0.7 no signal
711 Hepatic Cytolysis 5 0.7 0.7 no signal
712 Laboratory Test Abnormal 12 0.7 0.7 no signal
713 Renal Disorder 19 0.7 0.7 no signal
714 Urinary Tract Infection 69 0.7 0.7 no signal
715 Cardiac Disorder 38 0.7 0.7 no signal
716 Pulmonary Mass 6 0.7 0.7 no signal
717 Oral Pain 9 0.7 0.7 no signal
718 Hypersensitivity 74 0.7 0.7 no signal
719 Respiratory Distress 11 0.7 0.7 no signal
720 Hypoacusis 17 0.7 0.7 no signal
721 Eyelid Ptosis 4 0.7 0.7 no signal
722 Seizure 45 0.7 0.7 no signal
723 Feeling Hot 24 0.7 0.7 no signal
724 Treatment Failure 32 0.7 0.7 no signal
725 Thyroid Disorder 6 0.7 0.7 no signal
726 Dyspnoea 220 0.7 0.7 no signal
727 Synovitis 7 0.7 0.7 no signal
728 Tenderness 4 0.7 0.7 no signal
729 Haemorrhage 40 0.7 0.7 no signal
730 Angina Pectoris 11 0.7 0.7 no signal
731 Hypoaesthesia 57 0.7 0.7 no signal
732 Transfusion 4 0.7 0.7 no signal
733 Product Prescribing Error 9 0.7 0.7 no signal
734 Hypotension 76 0.7 0.7 no signal
735 Pulmonary Oedema 17 0.7 0.7 no signal
736 Incontinence 4 0.7 0.7 no signal
737 Night Sweats 12 0.7 0.7 no signal
738 Flushing 38 0.7 0.7 no signal
739 Hypoxia 13 0.7 0.6 no signal
740 Laryngitis 4 0.6 0.6 no signal
741 Wound Infection 4 0.6 0.6 no signal
742 Pulmonary Fibrosis 7 0.6 0.6 no signal
743 Musculoskeletal Disorder 7 0.6 0.6 no signal
744 Acute Respiratory Failure 7 0.6 0.6 no signal
745 Heart Rate Increased 36 0.6 0.6 no signal
746 Diverticulitis 10 0.6 0.6 no signal
747 Malnutrition 4 0.6 0.6 no signal
748 Thrombosis 29 0.6 0.6 no signal
749 Aphonia 5 0.6 0.6 no signal
750 Cough 100 0.6 0.6 no signal
751 Blood Test Abnormal 5 0.6 0.6 no signal
752 Pain 219 0.6 0.6 no signal
753 Femur Fracture 11 0.6 0.6 no signal
754 Mitral Valve Incompetence 4 0.6 0.6 no signal
755 Dysuria 13 0.6 0.6 no signal
756 Cholecystectomy 4 0.6 0.6 no signal
757 Swollen Tongue 11 0.6 0.6 no signal
758 Paralysis 5 0.6 0.6 no signal
759 Anuria 3 0.6 0.6 no signal
760 Skin Haemorrhage 5 0.6 0.6 no signal
761 Gastrointestinal Haemorrhage 29 0.6 0.6 no signal
762 Paraesthesia 54 0.6 0.6 no signal
763 Dysphonia 20 0.6 0.6 no signal
764 Splenomegaly 4 0.6 0.6 no signal
765 Therapy Non-responder 15 0.6 0.6 no signal
766 Colon Cancer 5 0.6 0.6 no signal
767 Toxicity To Various Agents 56 0.6 0.6 no signal
768 Eye Pruritus 11 0.6 0.6 no signal
769 Therapy Interrupted 23 0.6 0.6 no signal
770 Abdominal Pain Upper 68 0.6 0.6 no signal
771 Haemoglobin Decreased 34 0.6 0.6 no signal
772 Blood Count Abnormal 5 0.6 0.6 no signal
773 Blood Thyroid Stimulating Hormone Increased 3 0.6 0.6 no signal
774 Rectal Haemorrhage 14 0.6 0.6 no signal
775 Device Related Infection 5 0.6 0.6 no signal
776 Wound 9 0.6 0.6 no signal
777 Haematotoxicity 3 0.6 0.6 no signal
778 Balance Disorder 28 0.6 0.6 no signal
779 Tendonitis 5 0.6 0.6 no signal
780 Pneumothorax 5 0.6 0.6 no signal
781 Abscess 5 0.6 0.5 no signal
782 Cystitis 10 0.5 0.5 no signal
783 White Blood Cell Count Increased 12 0.5 0.5 no signal
784 Intraocular Pressure Increased 4 0.5 0.5 no signal
785 Sensory Disturbance 5 0.5 0.5 no signal
786 Respiratory Tract Infection 8 0.5 0.5 no signal
787 Haematoma 8 0.5 0.5 no signal
788 Cerebrovascular Accident 52 0.5 0.5 no signal
789 Immune System Disorder 4 0.5 0.5 no signal
790 Chest Pain 56 0.5 0.5 no signal
791 Back Pain 69 0.5 0.5 no signal
792 Acute Hepatic Failure 4 0.5 0.5 no signal
793 Circulatory Collapse 5 0.5 0.5 no signal
794 Osteoporosis 12 0.5 0.5 no signal
795 Peripheral Coldness 4 0.5 0.5 no signal
796 Peritonitis 6 0.5 0.5 no signal
797 Drug Administration Error 9 0.5 0.5 no signal
798 Pollakiuria 12 0.5 0.5 no signal
799 Oral Discomfort 4 0.5 0.5 no signal
800 Insomnia 76 0.5 0.5 no signal
801 Coordination Abnormal 4 0.5 0.5 no signal
802 Acute Respiratory Distress Syndrome 5 0.5 0.5 no signal
803 Upper Respiratory Tract Infection 13 0.5 0.5 no signal
804 Hip Fracture 9 0.5 0.5 no signal
805 Red Blood Cell Count Decreased 8 0.5 0.5 no signal
806 Bronchospasm 4 0.5 0.5 no signal
807 Influenza Like Illness 23 0.5 0.5 no signal
808 Eczema 14 0.5 0.5 no signal
809 Lethargy 16 0.5 0.5 no signal
810 Product Dispensing Error 6 0.5 0.5 no signal
811 Hypokinesia 4 0.5 0.5 no signal
812 Dyspepsia 27 0.5 0.5 no signal
813 Impaired Healing 9 0.5 0.5 no signal
814 Pruritus Generalised 6 0.5 0.5 no signal
815 Myocardial Infarction 48 0.5 0.5 no signal
816 Coma 13 0.5 0.5 no signal
817 Bone Disorder 5 0.5 0.5 no signal
818 Immunodeficiency 4 0.5 0.5 no signal
819 Gastrointestinal Disorder 24 0.5 0.5 no signal
820 Bacterial Infection 5 0.5 0.5 no signal
821 Eye Irritation 15 0.5 0.5 no signal
822 Malaise 118 0.5 0.5 no signal
823 Neck Pain 15 0.5 0.5 no signal
824 Shock 6 0.5 0.5 no signal
825 Eructation 5 0.5 0.5 no signal
826 Gait Disturbance 50 0.5 0.5 no signal
827 Delirium 9 0.5 0.5 no signal
828 Amnesia 17 0.5 0.5 no signal
829 Gastric Disorder 9 0.5 0.5 no signal
830 Hyperkalaemia 9 0.5 0.5 no signal
831 Kidney Infection 5 0.4 0.4 no signal
832 Skin Burning Sensation 18 0.4 0.4 no signal
833 Activities Of Daily Living Impaired 5 0.4 0.4 no signal
834 Mental Impairment 6 0.4 0.4 no signal
835 Deep Vein Thrombosis 16 0.4 0.4 no signal
836 Cholelithiasis 8 0.4 0.4 no signal
837 International Normalised Ratio Increased 7 0.4 0.4 no signal
838 Infusion Related Reaction 16 0.4 0.4 no signal
839 Libido Decreased 3 0.4 0.4 no signal
840 Bronchitis 18 0.4 0.4 no signal
841 Gait Inability 8 0.4 0.4 no signal
842 Staphylococcal Infection 8 0.4 0.4 no signal
843 Viral Infection 8 0.4 0.4 no signal
844 Cytomegalovirus Infection 4 0.4 0.4 no signal
845 Fungal Infection 8 0.4 0.4 no signal
846 Amenorrhoea 4 0.4 0.4 no signal
847 Tinnitus 11 0.4 0.4 no signal
848 Anaphylactic Reaction 13 0.4 0.4 no signal
849 Urinary Incontinence 7 0.4 0.4 no signal
850 Transient Ischaemic Attack 8 0.4 0.4 no signal
851 Haematemesis 6 0.4 0.4 no signal
852 Blood Cholesterol Increased 11 0.4 0.4 no signal
853 Cardiovascular Disorder 6 0.4 0.4 no signal
854 Cardiac Failure Congestive 19 0.4 0.4 no signal
855 Anaphylactic Shock 6 0.4 0.4 no signal
856 Respiratory Disorder 7 0.4 0.4 no signal
857 Arthropathy 13 0.4 0.4 no signal
858 Palpitations 27 0.4 0.4 no signal
859 Clostridium Difficile Infection 5 0.4 0.4 no signal
860 Faeces Discoloured 5 0.4 0.4 no signal
861 Somnolence 46 0.4 0.4 no signal
862 Head Discomfort 4 0.4 0.4 no signal
863 Diabetes Mellitus Inadequate Control 4 0.4 0.4 no signal
864 Diabetes Mellitus 17 0.4 0.4 no signal
865 Dyskinesia 9 0.4 0.4 no signal
866 Metabolic Acidosis 7 0.4 0.4 no signal
867 Gastroenteritis Viral 4 0.4 0.4 no signal
868 Restless Legs Syndrome 4 0.4 0.4 no signal
869 Memory Impairment 30 0.4 0.4 no signal
870 Skin Irritation 10 0.4 0.4 no signal
871 Product Use In Unapproved Indication 53 0.4 0.4 no signal
872 Movement Disorder 7 0.4 0.4 no signal
873 Chest Discomfort 22 0.4 0.4 no signal
874 Drug Ineffective For Unapproved Indication 12 0.4 0.4 no signal
875 Discomfort 13 0.4 0.4 no signal
876 Increased Appetite 4 0.4 0.4 no signal
877 Skin Fissures 4 0.4 0.4 no signal
878 Abdominal Distension 22 0.4 0.4 no signal
879 Blood Urine Present 4 0.4 0.4 no signal
880 Mobility Decreased 15 0.4 0.4 no signal
881 Abdominal Discomfort 35 0.4 0.4 no signal
882 Blood Pressure Fluctuation 5 0.4 0.4 no signal
883 Anosmia 3 0.4 0.4 no signal
884 Presyncope 5 0.4 0.4 no signal
885 Localised Infection 5 0.4 0.4 no signal
886 Apathy 3 0.4 0.4 no signal
887 Choking 4 0.4 0.4 no signal
888 Musculoskeletal Stiffness 18 0.4 0.4 no signal
889 Tremor 34 0.4 0.4 no signal
890 Psychotic Disorder 6 0.4 0.4 no signal
891 Loss Of Consciousness 26 0.4 0.4 no signal
892 Blood Pressure Increased 31 0.4 0.4 no signal
893 Spinal Fracture 4 0.4 0.4 no signal
894 Epistaxis 15 0.4 0.4 no signal
895 Hallucination 15 0.4 0.4 no signal
896 Upper Limb Fracture 4 0.4 0.4 no signal
897 Dizziness 99 0.3 0.3 no signal
898 Lower Respiratory Tract Infection 9 0.3 0.3 no signal
899 Full Blood Count Decreased 4 0.3 0.3 no signal
900 Contusion 19 0.3 0.3 no signal
901 Abdominal Pain Lower 5 0.3 0.3 no signal
902 Fluid Retention 10 0.3 0.3 no signal
903 Muscle Spasms 36 0.3 0.3 no signal
904 Bone Marrow Failure 4 0.3 0.3 no signal
905 Lung Neoplasm Malignant 8 0.3 0.3 no signal
906 Cognitive Disorder 9 0.3 0.3 no signal
907 Acute Myeloid Leukaemia 3 0.3 0.3 no signal
908 Pulmonary Hypertension 4 0.3 0.3 no signal
909 Restlessness 7 0.3 0.3 no signal
910 Drug Ineffective 251 0.3 0.3 no signal
911 Productive Cough 9 0.3 0.3 no signal
912 Osteoarthritis 8 0.3 0.3 no signal
913 Depression 43 0.3 0.3 no signal
914 Fall 62 0.3 0.3 no signal
915 Frequent Bowel Movements 5 0.3 0.3 no signal
916 Throat Tightness 5 0.3 0.3 no signal
917 Unevaluable Event 14 0.3 0.3 no signal
918 Dementia 5 0.3 0.3 no signal
919 Colitis Ulcerative 8 0.3 0.3 no signal
920 Feeling Cold 5 0.3 0.3 no signal
921 Plasma Cell Myeloma 7 0.3 0.3 no signal
922 Throat Irritation 8 0.3 0.3 no signal
923 Nephrolithiasis 8 0.3 0.3 no signal
924 Gastrooesophageal Reflux Disease 14 0.3 0.3 no signal
925 Muscle Twitching 4 0.3 0.3 no signal
926 Pancreatic Carcinoma 5 0.3 0.3 no signal
927 Sleep Disorder 12 0.3 0.3 no signal
928 Dysstasia 5 0.3 0.3 no signal
929 Therapeutic Product Effect Incomplete 12 0.3 0.3 no signal
930 Diabetic Ketoacidosis 4 0.3 0.3 no signal
931 Hospitalisation 25 0.3 0.3 no signal
932 Cerebral Infarction 4 0.3 0.3 no signal
933 Mental Disorder 7 0.3 0.3 no signal
934 Pneumonia Aspiration 4 0.3 0.3 no signal
935 Extrapyramidal Disorder 4 0.3 0.3 no signal
936 Adverse Drug Reaction 14 0.3 0.3 no signal
937 Depressed Level Of Consciousness 6 0.3 0.3 no signal
938 Ear Infection 4 0.3 0.3 no signal
939 Abnormal Behaviour 6 0.3 0.3 no signal
940 Mood Altered 4 0.3 0.3 no signal
941 Disease Recurrence 7 0.3 0.3 no signal
942 Pallor 4 0.3 0.3 no signal
943 Hot Flush 11 0.3 0.3 no signal
944 Medication Error 8 0.3 0.3 no signal
945 Anxiety 41 0.3 0.2 no signal
946 Altered State Of Consciousness 3 0.2 0.2 no signal
947 Intentional Product Misuse 12 0.2 0.2 no signal
948 Drug Effective For Unapproved Indication 4 0.2 0.2 no signal
949 Underdose 10 0.2 0.2 no signal
950 Blood Pressure Decreased 9 0.2 0.2 no signal
951 Therapeutic Product Effect Decreased 6 0.2 0.2 no signal
952 Chronic Obstructive Pulmonary Disease 7 0.2 0.2 no signal
953 Coronary Artery Disease 4 0.2 0.2 no signal
954 Limb Discomfort 4 0.2 0.2 no signal
955 Gynaecomastia 4 0.2 0.2 no signal
956 Sinusitis 13 0.2 0.2 no signal
957 Influenza 14 0.2 0.2 no signal
958 Nasopharyngitis 23 0.2 0.2 no signal
959 Hepatic Cancer 3 0.2 0.2 no signal
960 Surgery 7 0.2 0.2 no signal
961 Cardiac Arrest 10 0.2 0.2 no signal
962 Urinary Retention 4 0.2 0.2 no signal
963 Illness 12 0.2 0.2 no signal
964 Bradycardia 6 0.2 0.2 no signal
965 Crying 4 0.2 0.2 no signal
966 Accidental Overdose 4 0.2 0.2 no signal
967 Wrong Technique In Drug Usage Process 4 0.2 0.2 no signal
968 Feeling Abnormal 26 0.2 0.2 no signal
969 Condition Aggravated 32 0.2 0.2 no signal
970 Wrong Technique In Product Usage Process 21 0.2 0.2 no signal
971 Hypoglycaemia 5 0.2 0.2 no signal
972 Suicidal Ideation 9 0.2 0.2 no signal
973 Weight Increased 21 0.2 0.2 no signal
974 Vaginal Haemorrhage 4 0.2 0.2 no signal
975 Rhinorrhoea 6 0.2 0.2 no signal
976 Hyperhidrosis 12 0.2 0.2 no signal
977 Product Storage Error 8 0.2 0.2 no signal
978 Disturbance In Attention 5 0.2 0.2 no signal
979 Chronic Kidney Disease 7 0.2 0.2 no signal
980 Prostate Cancer 7 0.2 0.2 no signal
981 Therapeutic Response Decreased 5 0.1 0.1 no signal
982 Drug Hypersensitivity 16 0.1 0.1 no signal
983 Agitation 6 0.1 0.1 no signal
984 Covid-19 14 0.1 0.1 no signal
985 Drug Dose Omission 13 0.1 0.1 no signal
986 Breast Cancer 7 0.1 0.1 no signal
987 Blood Glucose Increased 13 0.1 0.1 no signal
988 Incorrect Dose Administered 15 0.1 0.1 no signal
989 Rheumatoid Arthritis 7 0.1 0.1 no signal
990 Product Dose Omission 4 0.1 0.1 no signal
991 Product Dose Omission Issue 16 0.1 0.1 no signal
992 Product Use Issue 10 0.1 0.1 no signal
993 Migraine 5 0.1 0.1 no signal
994 Bladder Cancer 3 0.1 0.1 no signal
995 Foetal Exposure During Pregnancy 4 0.1 0.1 no signal
996 Overdose 10 0.1 0.1 no signal
997 Maternal Exposure During Pregnancy 4 0.1 0.1 no signal
998 Injection Site Pain 10 0.1 0.1 no signal
999 Adverse Event 3 0.1 0.1 no signal
1000 Product Quality Issue 4 0.1 0.1 no signal