OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Vitamin E

1,193 flagged reaction(s) · 158,126 total co-reports · max PRR 366.4
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Fractional Exhaled Nitric Oxide Increased 61 366.4 367.1 signal
2 Sleep Disorder Therapy 49 239.8 240.2 signal
3 Antacid Therapy 30 222.7 222.9 signal
4 Appendicolith 93 217.9 218.6 signal
5 Vaginal Flatulence 62 170.7 171.0 signal
6 Analgesic Therapy 51 133.7 133.9 signal
7 Drug Therapy 50 124.2 124.4 signal
8 Post Cholecystectomy Syndrome 40 111.1 111.2 signal
9 Anticoagulant Therapy 31 84.3 84.4 signal
10 Granulocyte Count Increased 40 73.4 73.5 signal
11 Electric Shock 68 58.4 58.6 signal
12 Blood Immunoglobulin A Increased 41 55.5 55.6 signal
13 Vitamin B12 Increased 53 48.1 48.2 signal
14 Glomerular Filtration Rate Increased 43 37.4 37.5 signal
15 Obstructive Sleep Apnoea Syndrome 59 29.6 29.6 signal
16 Dactylitis 41 29.2 29.2 signal
17 Myoglobin Blood Increased 62 28.2 28.3 signal
18 Female Genital Tract Fistula 67 27.1 27.2 signal
19 Intervertebral Discitis 73 26.9 26.9 signal
20 Blood Phosphorus Increased 101 25.8 25.9 signal
21 Rheumatoid Factor Increased 41 25.5 25.5 signal
22 Anaemia Postoperative 46 24.3 24.3 signal
23 Hyperphosphataemia 73 23.9 23.9 signal
24 Intramedullary Rod Insertion 71 23.7 23.7 signal
25 Open Reduction Of Fracture 37 22.1 22.1 signal
26 Cystocele 27 21.6 21.6 signal
27 Radiculopathy 82 21.5 21.5 signal
28 Muscle Cramp 52 19.9 20.0 signal
29 Chronic Sinusitis 103 18.9 19.0 signal
30 Blood Uric Acid Increased 144 17.1 17.2 signal
31 Proctitis 70 17.1 17.2 signal
32 Joint Noise 48 17.0 17.0 signal
33 Plantar Fasciitis 81 16.5 16.6 signal
34 Brain Natriuretic Peptide Increased 74 16.5 16.5 signal
35 Low Turnover Osteopathy 97 16.4 16.5 signal
36 Spondylolisthesis 40 15.7 15.8 signal
37 Fracture Nonunion 31 15.4 15.5 signal
38 Infective Pulmonary Exacerbation Of Cystic Fibrosis 115 14.3 14.4 signal
39 Total Lung Capacity Decreased 33 14.1 14.1 signal
40 Osteosclerosis 32 13.9 13.9 signal
41 White Blood Cells Urine Positive 37 13.5 13.5 signal
42 Hyperparathyroidism Secondary 50 13.5 13.5 signal
43 Aspartate Aminotransferase Abnormal 29 13.1 13.1 signal
44 Lumbar Spinal Stenosis 55 12.8 12.8 signal
45 Iron Deficiency 80 12.3 12.3 signal
46 Demyelination 73 12.1 12.1 signal
47 Aortic Stenosis 61 11.9 12.0 signal
48 Kyphosis 31 11.9 11.9 signal
49 Macular Degeneration 196 11.2 11.3 signal
50 Hyperlipidaemia 192 10.9 11.0 signal
51 Nephrogenic Anaemia 74 10.8 10.8 signal
52 Ventricular Hypertrophy 40 10.7 10.8 signal
53 Colonic Polyp 26 10.6 10.6 signal
54 Aortic Arteriosclerosis 40 10.5 10.6 signal
55 Spinal Osteoarthritis 134 10.3 10.4 signal
56 Essential Hypertension 39 10.2 10.2 signal
57 Vitamin B12 Deficiency 60 10.1 10.2 signal
58 Exostosis 136 10.1 10.2 signal
59 Monocyte Count Increased 53 9.9 9.9 signal
60 Intervertebral Disc Degeneration 132 9.6 9.7 signal
61 Activated Partial Thromboplastin Time Prolonged 72 9.6 9.6 signal
62 Vitamin D Deficiency 132 9.2 9.2 signal
63 Post-traumatic Stress Disorder 87 8.8 8.8 signal
64 Throat Clearing 48 8.8 8.8 signal
65 Difficulty In Walking 45 8.7 8.8 signal
66 Lung Opacity 31 8.2 8.2 signal
67 Stress Fracture 64 8.0 8.0 signal
68 Blood Pressure Systolic Decreased 53 7.9 8.0 signal
69 Myasthenia Gravis 92 7.9 7.9 signal
70 Carotid Artery Stenosis 41 7.9 7.9 signal
71 Diverticulum 84 7.9 7.9 signal
72 Appendicitis 107 7.8 7.8 signal
73 Renal Cyst 90 7.7 7.7 signal
74 Benign Prostatic Hyperplasia 58 7.6 7.6 signal
75 Hypophosphataemia 81 7.5 7.5 signal
76 Mitral Valve Incompetence 123 7.4 7.4 signal
77 Spinal Column Stenosis 52 7.4 7.4 signal
78 Endodontic Procedure 27 7.2 7.2 signal
79 Aortic Valve Incompetence 45 7.1 7.1 signal
80 Temperature Intolerance 107 7.1 7.1 signal
81 Cholecystitis Acute 59 7.1 7.1 signal
82 Blood Calcium Increased 91 7.0 7.0 signal
83 Low Density Lipoprotein Increased 78 6.9 6.9 signal
84 Rhinitis Allergic 45 6.9 6.9 signal
85 Ventricular Fibrillation 112 6.8 6.8 signal
86 Loose Tooth 32 6.7 6.7 signal
87 Renal Failure Chronic 77 6.7 6.7 signal
88 Ulcer 153 6.5 6.5 signal
89 Sensation Of Foreign Body 80 6.5 6.5 signal
90 Increased Upper Airway Secretion 49 6.4 6.4 signal
91 Rebound Acid Hypersecretion 29 6.4 6.4 signal
92 Progressive Multifocal Leukoencephalopathy 78 6.4 6.4 signal
93 Peripheral Vascular Disorder 49 6.4 6.4 signal
94 Orthopnoea 30 6.4 6.4 signal
95 Atelectasis 91 6.3 6.4 signal
96 Bursitis 113 6.3 6.3 signal
97 Muscle Spasticity 116 6.3 6.3 signal
98 Scoliosis 58 6.3 6.3 signal
99 Peptic Ulcer 31 6.3 6.3 signal
100 Femur Fracture 289 6.3 6.3 signal
101 Body Height Decreased 99 6.2 6.2 signal
102 Hepatic Cyst 31 6.2 6.2 signal
103 Blood Test Abnormal 128 6.2 6.2 signal
104 Osteopenia 139 6.2 6.2 signal
105 Oral Candidiasis 118 6.1 6.1 signal
106 Pre-existing Condition Improved 57 6.1 6.1 signal
107 Muscle Strain 78 6.1 6.1 signal
108 Stomach Discomfort 47 6.1 6.1 signal
109 Haemorrhagic Anaemia 40 6.1 6.1 signal
110 Coronary Artery Disease 271 6.0 6.0 signal
111 Osteoarthritis 373 5.9 6.0 signal
112 Hypercholesterolaemia 84 5.9 5.9 signal
113 Vaginal Discharge 87 5.8 5.9 signal
114 Cataract Operation 51 5.8 5.8 signal
115 Seasonal Allergy 121 5.8 5.8 signal
116 Angina Unstable 56 5.8 5.8 signal
117 Ear Pain 165 5.7 5.8 signal
118 Snoring 32 5.7 5.7 signal
119 Epigastric Discomfort 33 5.7 5.7 signal
120 Pulmonary Function Test Decreased 37 5.7 5.7 signal
121 Decreased Interest 49 5.6 5.6 signal
122 Gingival Disorder 32 5.6 5.6 signal
123 Diabetic Retinopathy 28 5.6 5.6 signal
124 Blood Cholesterol Increased 381 5.5 5.6 signal
125 Left Ventricular Hypertrophy 35 5.5 5.5 signal
126 Dental Caries 90 5.5 5.5 signal
127 Paraesthesia Oral 117 5.5 5.5 signal
128 Blood Pressure Diastolic Decreased 60 5.5 5.5 signal
129 Troponin Increased 61 5.5 5.5 signal
130 Secretion Discharge 99 5.4 5.4 signal
131 Spinal Disorder 76 5.4 5.4 signal
132 Tricuspid Valve Incompetence 63 5.4 5.4 signal
133 Joint Effusion 55 5.4 5.4 signal
134 Neuralgia 192 5.3 5.4 signal
135 Coordination Abnormal 111 5.3 5.3 signal
136 Multiple Allergies 62 5.3 5.3 signal
137 End Stage Renal Disease 145 5.3 5.3 signal
138 Spinal Compression Fracture 66 5.3 5.3 signal
139 Glucose Tolerance Impaired 46 5.3 5.3 signal
140 Faecal Incontinence 38 5.3 5.3 signal
141 Bone Lesion 28 5.2 5.2 signal
142 Therapy Cessation 396 5.2 5.3 signal
143 Obstructive Airways Disorder 86 5.2 5.2 signal
144 Micturition Urgency 87 5.2 5.2 signal
145 Tibia Fracture 36 5.2 5.2 signal
146 Cardiogenic Shock 109 5.2 5.2 signal
147 Hiatus Hernia 99 5.1 5.2 signal
148 Meniscus Injury 47 5.1 5.2 signal
149 Rotator Cuff Syndrome 98 5.1 5.1 signal
150 International Normalised Ratio Decreased 31 5.1 5.1 signal
151 Atrioventricular Block First Degree 33 5.1 5.1 signal
152 Synovial Cyst 35 5.1 5.1 signal
153 Cerebral Atrophy 30 5.1 5.1 signal
154 Hyperkeratosis 41 5.0 5.0 signal
155 Bundle Branch Block Right 34 5.0 5.0 signal
156 Appendicectomy 26 4.9 4.9 signal
157 Nocturia 88 4.9 4.9 signal
158 Pharyngolaryngeal Pain 39 4.9 4.9 signal
159 Gingivitis 39 4.9 4.9 signal
160 Cystic Fibrosis 40 4.8 4.9 signal
161 Cardiomegaly 89 4.8 4.8 signal
162 Compression Fracture 37 4.8 4.8 signal
163 Iron Deficiency Anaemia 64 4.7 4.7 signal
164 Incorrect Route Of Product Administration 117 4.7 4.7 signal
165 Oral Infection 27 4.7 4.7 signal
166 Dyslipidaemia 35 4.6 4.6 signal
167 Adrenal Insufficiency 82 4.6 4.6 signal
168 Intervertebral Disc Protrusion 150 4.6 4.6 signal
169 Bacterial Infection 127 4.6 4.6 signal
170 Blood Urea Increased 115 4.6 4.6 signal
171 Infusion Site Swelling 42 4.6 4.6 signal
172 Bundle Branch Block Left 29 4.6 4.6 signal
173 Intervertebral Disc Disorder 29 4.5 4.6 signal
174 Sleep Apnoea Syndrome 129 4.5 4.6 signal
175 Lung Neoplasm 29 4.5 4.5 signal
176 Dyspnoea Exertional 252 4.5 4.6 signal
177 Visual Disturbance 39 4.5 4.5 signal
178 Pneumothorax 106 4.5 4.5 signal
179 Coronary Artery Occlusion 91 4.5 4.5 signal
180 Groin Pain 58 4.4 4.4 signal
181 Sciatica 104 4.4 4.4 signal
182 Hepatic Steatosis 122 4.4 4.4 signal
183 Gastrooesophageal Reflux Disease 522 4.4 4.4 signal
184 Arteriosclerosis Coronary Artery 43 4.4 4.4 signal
185 Red Blood Cell Count Decreased 186 4.4 4.4 signal
186 Sinus Disorder 128 4.3 4.4 signal
187 Cardiac Murmur 56 4.3 4.3 signal
188 Tendonitis 100 4.3 4.3 signal
189 Foot Fracture 122 4.3 4.3 signal
190 Red Blood Cell Sedimentation Rate Increased 71 4.3 4.3 signal
191 Gout 115 4.3 4.3 signal
192 Laceration 61 4.3 4.3 signal
193 Vitreous Floaters 62 4.3 4.3 signal
194 Upper-airway Cough Syndrome 52 4.3 4.3 signal
195 Carpal Tunnel Syndrome 89 4.3 4.3 signal
196 Squamous Cell Carcinoma Of Skin 38 4.3 4.3 signal
197 Bone Disorder 115 4.2 4.2 signal
198 Ventricular Extrasystoles 65 4.2 4.2 signal
199 Lymphoedema 43 4.2 4.2 signal
200 Balance Disorder 539 4.2 4.3 signal
201 Diverticulum Intestinal 27 4.2 4.2 signal
202 Dry Mouth 501 4.2 4.2 signal
203 Jaw Disorder 34 4.1 4.1 signal
204 Sputum Discoloured 58 4.1 4.1 signal
205 Pathological Fracture 31 4.1 4.1 signal
206 Ligament Sprain 60 4.1 4.1 signal
207 Initial Insomnia 62 4.1 4.1 signal
208 Diabetic Neuropathy 30 4.1 4.1 signal
209 Rib Fracture 123 4.0 4.0 signal
210 Prothrombin Time Prolonged 36 4.0 4.0 signal
211 Arteriosclerosis 56 4.0 4.0 signal
212 Neutrophil Count Increased 61 4.0 4.0 signal
213 Haemorrhoids 115 4.0 4.0 signal
214 Oesophagitis 64 3.9 3.9 signal
215 Lung Infiltration 52 3.9 3.9 signal
216 Bladder Disorder 58 3.9 3.9 signal
217 Bronchitis 433 3.9 4.0 signal
218 Tendon Pain 44 3.9 3.9 signal
219 Hysterectomy 50 3.9 3.9 signal
220 Cyst 72 3.9 3.9 signal
221 Pelvic Fracture 45 3.9 3.9 signal
222 Humerus Fracture 28 3.9 3.9 signal
223 Exercise Tolerance Decreased 33 3.9 3.9 signal
224 Miosis 46 3.9 3.9 signal
225 Flatulence 326 3.9 3.9 signal
226 Nerve Compression 53 3.9 3.9 signal
227 Musculoskeletal Chest Pain 89 3.9 3.9 signal
228 Tooth Fracture 63 3.8 3.9 signal
229 Osteoporosis 235 3.8 3.9 signal
230 Sinus Headache 34 3.8 3.8 signal
231 Rales 33 3.8 3.8 signal
232 Wrist Fracture 68 3.8 3.8 signal
233 Blood Triglycerides Increased 100 3.8 3.8 signal
234 Large Intestine Polyp 39 3.8 3.8 signal
235 Chronic Obstructive Pulmonary Disease 293 3.8 3.8 signal
236 Ankle Fracture 87 3.8 3.8 signal
237 Oral Pain 126 3.8 3.8 signal
238 Vitamin D Decreased 48 3.8 3.8 signal
239 Joint Injury 119 3.7 3.8 signal
240 Night Sweats 179 3.7 3.8 signal
241 Sinusitis 571 3.7 3.8 signal
242 Cataract 329 3.7 3.8 signal
243 Urinary Incontinence 164 3.7 3.7 signal
244 Decubitus Ulcer 45 3.7 3.7 signal
245 Dry Throat 56 3.7 3.7 signal
246 Ascites 162 3.7 3.7 signal
247 Rhinitis 44 3.7 3.7 signal
248 Peroneal Nerve Palsy 31 3.7 3.7 signal
249 Obsessive-compulsive Disorder 44 3.7 3.7 signal
250 Uterine Leiomyoma 40 3.7 3.7 signal
251 Walking Aid User 36 3.7 3.7 signal
252 Impaired Healing 178 3.6 3.7 signal
253 Blood Alkaline Phosphatase Increased 134 3.6 3.6 signal
254 Dyspepsia 527 3.6 3.7 signal
255 Transient Ischaemic Attack 182 3.6 3.6 signal
256 Haematocrit Decreased 107 3.6 3.6 signal
257 Coronary Artery Stenosis 27 3.6 3.6 signal
258 Irritable Bowel Syndrome 114 3.6 3.6 signal
259 Blood Sodium Decreased 100 3.6 3.6 signal
260 Osteomyelitis 96 3.6 3.6 signal
261 Weight Fluctuation 55 3.6 3.6 signal
262 Breath Sounds Abnormal 26 3.5 3.5 signal
263 Food Poisoning 28 3.5 3.5 signal
264 Flank Pain 49 3.5 3.5 signal
265 Skin Atrophy 30 3.5 3.5 signal
266 Foot Deformity 58 3.5 3.5 signal
267 Tendon Disorder 34 3.5 3.5 signal
268 Blood Pressure Fluctuation 125 3.5 3.5 signal
269 Stress 373 3.5 3.5 signal
270 Arthritis 406 3.5 3.5 signal
271 Gingival Pain 41 3.5 3.5 signal
272 Body Temperature Increased 105 3.5 3.5 signal
273 Constipation 1,109 3.4 3.5 signal
274 Dermatitis Contact 58 3.4 3.4 signal
275 Hot Flush 385 3.4 3.5 signal
276 Increased Tendency To Bruise 47 3.4 3.4 signal
277 Ammonia Increased 26 3.4 3.4 signal
278 Limb Injury 138 3.4 3.4 signal
279 Ecchymosis 35 3.4 3.4 signal
280 Tooth Abscess 52 3.4 3.4 signal
281 Toothache 92 3.4 3.4 signal
282 Weight Decreased 1,416 3.4 3.5 signal
283 Oedema Peripheral 620 3.4 3.5 signal
284 Neuropathy Peripheral 479 3.4 3.4 signal
285 Dysphonia 295 3.4 3.4 signal
286 Polyp 33 3.4 3.4 signal
287 Arthropod Bite 37 3.4 3.4 signal
288 Gastroenteritis Viral 91 3.4 3.4 signal
289 Dry Eye 243 3.4 3.4 signal
290 Aspartate Aminotransferase Increased 266 3.4 3.4 signal
291 Pain In Jaw 142 3.4 3.4 signal
292 Cerebral Ischaemia 26 3.4 3.4 signal
293 Atrial Flutter 40 3.4 3.4 signal
294 Bowel Movement Irregularity 38 3.4 3.4 signal
295 Tooth Disorder 111 3.3 3.4 signal
296 Procedural Pain 137 3.3 3.3 signal
297 Dysstasia 145 3.3 3.3 signal
298 Gastritis 130 3.3 3.3 signal
299 Rectal Haemorrhage 213 3.3 3.3 signal
300 Back Pain 1,146 3.3 3.4 signal
301 Blood Testosterone Decreased 34 3.3 3.3 signal
302 Skin Laceration 53 3.3 3.3 signal
303 Oral Disorder 36 3.3 3.3 signal
304 Dizziness Postural 47 3.3 3.3 signal
305 Muscle Injury 40 3.3 3.3 signal
306 Abdominal Distension 506 3.3 3.3 signal
307 Pharmaceutical Product Complaint 128 3.3 3.3 signal
308 Upper Respiratory Tract Infection 224 3.3 3.3 signal
309 Chronic Kidney Disease 372 3.3 3.3 signal
310 Herpes Virus Infection 28 3.3 3.3 signal
311 Restless Legs Syndrome 88 3.3 3.3 signal
312 Blood Potassium Decreased 145 3.2 3.3 signal
313 Incontinence 51 3.2 3.2 signal
314 Onychoclasis 33 3.2 3.2 signal
315 Economic Problem 74 3.2 3.2 signal
316 Abasia 120 3.2 3.2 signal
317 Joint Range Of Motion Decreased 64 3.2 3.2 signal
318 Blood Calcium Decreased 54 3.2 3.2 signal
319 Contusion 460 3.2 3.3 signal
320 Middle Insomnia 89 3.2 3.2 signal
321 Scar 82 3.2 3.2 signal
322 Concussion 37 3.2 3.2 signal
323 Parosmia 36 3.2 3.2 signal
324 Breast Mass 32 3.2 3.2 signal
325 Pollakiuria 198 3.2 3.2 signal
326 Anorexia 62 3.2 3.2 signal
327 Body Temperature Decreased 47 3.2 3.2 signal
328 Eye Pain 261 3.2 3.2 signal
329 Extrasystoles 33 3.2 3.2 signal
330 Multiple Injuries 30 3.2 3.2 signal
331 Nephrolithiasis 215 3.2 3.2 signal
332 Muscle Tightness 76 3.2 3.2 signal
333 Cystitis 150 3.2 3.2 signal
334 Tenderness 49 3.2 3.2 signal
335 Muscle Atrophy 59 3.2 3.2 signal
336 Atrial Fibrillation 457 3.2 3.2 signal
337 Frequent Bowel Movements 126 3.2 3.2 signal
338 Blood Albumin Decreased 37 3.1 3.2 signal
339 Respiratory Disorder 140 3.1 3.1 signal
340 Decreased Activity 50 3.1 3.1 signal
341 Cholelithiasis 153 3.1 3.1 signal
342 Gastrointestinal Pain 51 3.1 3.1 signal
343 Pulmonary Mass 69 3.1 3.1 signal
344 Cardiac Flutter 30 3.1 3.1 signal
345 Nasal Dryness 29 3.1 3.1 signal
346 Aspiration 50 3.1 3.1 signal
347 Fibromyalgia 112 3.1 3.1 signal
348 Basal Cell Carcinoma 72 3.1 3.1 signal
349 Knee Arthroplasty 96 3.1 3.1 signal
350 Musculoskeletal Pain 243 3.1 3.1 signal
351 Multiple Sclerosis 221 3.1 3.1 signal
352 Back Disorder 75 3.1 3.1 signal
353 Ageusia 114 3.1 3.1 signal
354 Alanine Aminotransferase Increased 280 3.1 3.1 signal
355 Upper Limb Fracture 91 3.1 3.1 signal
356 Eructation 86 3.0 3.0 signal
357 Sinus Congestion 61 3.0 3.0 signal
358 Photophobia 84 3.0 3.0 signal
359 Muscle Spasms 824 3.0 3.1 signal
360 Muscular Weakness 510 3.0 3.1 signal
361 Hip Fracture 144 3.0 3.0 signal
362 Angina Pectoris 129 3.0 3.0 signal
363 Fall 1,480 3.0 3.1 signal
364 Heart Rate Irregular 101 3.0 3.0 signal
365 Erectile Dysfunction 114 3.0 3.0 signal
366 Muscle Disorder 36 3.0 3.0 signal
367 Ocular Discomfort 48 3.0 3.0 signal
368 Sleep Disorder 309 3.0 3.0 signal
369 Diverticulitis 122 3.0 3.0 signal
370 Blood Urine Present 84 3.0 3.0 signal
371 Cognitive Disorder 205 3.0 3.0 signal
372 Productive Cough 208 3.0 3.0 signal
373 Skin Infection 49 3.0 3.0 signal
374 Neck Pain 245 2.9 3.0 signal
375 Eye Infection 49 2.9 2.9 signal
376 Drooling 30 2.9 2.9 signal
377 Throat Irritation 195 2.9 2.9 signal
378 Flushing 445 2.9 3.0 signal
379 Nasal Congestion 255 2.9 2.9 signal
380 Bronchiectasis 29 2.9 2.9 signal
381 Feeling Jittery 83 2.9 2.9 signal
382 Tooth Extraction 54 2.9 2.9 signal
383 Hypothyroidism 138 2.9 2.9 signal
384 Impaired Gastric Emptying 55 2.9 2.9 signal
385 Wheezing 255 2.9 2.9 signal
386 Aortic Aneurysm 33 2.9 2.9 signal
387 Nerve Injury 48 2.9 2.9 signal
388 Pulmonary Hypertension 90 2.9 2.9 signal
389 Cellulitis 217 2.9 2.9 signal
390 Haematochezia 236 2.9 2.9 signal
391 Mass 60 2.9 2.9 signal
392 Joint Stiffness 112 2.9 2.9 signal
393 Type 2 Diabetes Mellitus 144 2.9 2.9 signal
394 Blood Potassium Increased 69 2.9 2.9 signal
395 Gait Disturbance 815 2.9 2.9 signal
396 Gallbladder Disorder 76 2.9 2.9 signal
397 Hand Fracture 30 2.8 2.8 signal
398 Cholecystectomy 48 2.8 2.8 signal
399 Hair Texture Abnormal 57 2.8 2.8 signal
400 Urinary Tract Infection 718 2.8 2.9 signal
401 Infusion Site Erythema 35 2.8 2.8 signal
402 Thyroid Disorder 65 2.8 2.8 signal
403 Pain In Extremity 1,243 2.8 2.9 signal
404 Post Procedural Infection 34 2.8 2.8 signal
405 Supraventricular Tachycardia 40 2.8 2.8 signal
406 Lower Gastrointestinal Haemorrhage 31 2.8 2.8 signal
407 Feeling Cold 116 2.8 2.8 signal
408 Anal Incontinence 37 2.8 2.8 signal
409 Hepatomegaly 41 2.8 2.8 signal
410 Tinnitus 191 2.8 2.8 signal
411 Hepatic Enzyme Increased 282 2.8 2.8 signal
412 Facial Pain 37 2.8 2.8 signal
413 Nail Disorder 36 2.8 2.8 signal
414 Refusal Of Treatment By Patient 27 2.8 2.8 signal
415 Hyperaesthesia 34 2.8 2.8 signal
416 Insurance Issue 61 2.8 2.8 signal
417 Arthropathy 229 2.8 2.8 signal
418 Malignant Melanoma 55 2.8 2.8 signal
419 Sensory Loss 33 2.7 2.7 signal
420 Hair Disorder 34 2.7 2.7 signal
421 Ovarian Cyst 41 2.7 2.7 signal
422 Asthenia 1,532 2.7 2.8 signal
423 Small Intestinal Obstruction 50 2.7 2.7 signal
424 Chest Discomfort 415 2.7 2.8 signal
425 Skin Mass 27 2.7 2.7 signal
426 Multiple Organ Dysfunction Syndrome 113 2.7 2.7 signal
427 Glycosylated Haemoglobin Increased 102 2.7 2.7 signal
428 Glaucoma 78 2.7 2.7 signal
429 Dysuria 149 2.7 2.7 signal
430 Haemoptysis 113 2.7 2.7 signal
431 Bone Pain 237 2.7 2.7 signal
432 Gastrointestinal Infection 36 2.7 2.7 signal
433 Sensory Disturbance 65 2.7 2.7 signal
434 Arthralgia 1,667 2.7 2.8 signal
435 Respiratory Tract Congestion 64 2.7 2.7 signal
436 Poor Quality Sleep 86 2.7 2.7 signal
437 Cough 1,122 2.7 2.8 signal
438 Insomnia 1,069 2.7 2.8 signal
439 Peripheral Swelling 612 2.7 2.7 signal
440 Depression 911 2.7 2.7 signal
441 Hypoaesthesia 597 2.7 2.7 signal
442 Tongue Disorder 29 2.7 2.7 signal
443 Burning Sensation 279 2.7 2.7 signal
444 Renal Pain 42 2.7 2.7 signal
445 White Blood Cell Count Increased 153 2.7 2.7 signal
446 Feeling Hot 243 2.7 2.7 signal
447 Blood Pressure Increased 606 2.7 2.7 signal
448 Impaired Driving Ability 45 2.7 2.7 signal
449 Thermal Burn 28 2.7 2.7 signal
450 Electrocardiogram Abnormal 31 2.6 2.6 signal
451 Chest Pain 729 2.6 2.7 signal
452 Head Injury 124 2.6 2.6 signal
453 Sinus Bradycardia 38 2.6 2.6 signal
454 Ear Discomfort 40 2.6 2.6 signal
455 Myalgia 663 2.6 2.7 signal
456 Local Swelling 69 2.6 2.6 signal
457 Post Procedural Complication 75 2.6 2.6 signal
458 Blood Pressure Systolic Increased 76 2.6 2.6 signal
459 Abdominal Pain Upper 792 2.6 2.6 signal
460 Emphysema 39 2.6 2.6 signal
461 Infusion Related Reaction 254 2.6 2.6 signal
462 Petechiae 40 2.6 2.6 signal
463 Gastroenteritis 56 2.6 2.6 signal
464 Herpes Zoster 221 2.6 2.6 signal
465 Musculoskeletal Discomfort 66 2.6 2.6 signal
466 Eating Disorder 82 2.6 2.6 signal
467 Eosinophilia 67 2.6 2.6 signal
468 Liver Function Test Abnormal 112 2.6 2.6 signal
469 Blood Magnesium Decreased 33 2.6 2.6 signal
470 Major Depression 28 2.6 2.6 signal
471 Squamous Cell Carcinoma 36 2.6 2.6 signal
472 Depressed Mood 201 2.6 2.6 signal
473 Full Blood Count Decreased 77 2.6 2.6 signal
474 Blood Iron Decreased 45 2.6 2.6 signal
475 Fungal Infection 127 2.6 2.6 signal
476 Chromaturia 86 2.6 2.6 signal
477 Skin Cancer 82 2.6 2.6 signal
478 Swelling 355 2.6 2.6 signal
479 Joint Dislocation 40 2.6 2.6 signal
480 Full Blood Count Abnormal 40 2.5 2.6 signal
481 Tooth Infection 50 2.5 2.6 signal
482 Diabetes Mellitus 290 2.5 2.6 signal
483 Back Injury 41 2.5 2.5 signal
484 Pulmonary Congestion 50 2.5 2.5 signal
485 Therapeutic Response Unexpected 170 2.5 2.5 signal
486 Heart Rate Decreased 133 2.5 2.5 signal
487 Paraesthesia 594 2.5 2.6 signal
488 Spinal Fracture 75 2.5 2.5 signal
489 Fluid Retention 191 2.5 2.5 signal
490 Thrombosis 303 2.5 2.5 signal
491 Musculoskeletal Stiffness 329 2.5 2.5 signal
492 Breast Pain 40 2.5 2.5 signal
493 Limb Discomfort 116 2.5 2.5 signal
494 Hepatic Cirrhosis 70 2.5 2.5 signal
495 Bipolar Disorder 41 2.5 2.5 signal
496 Dysphagia 353 2.5 2.5 signal
497 Gingival Bleeding 51 2.5 2.5 signal
498 Nephropathy 35 2.5 2.5 signal
499 Joint Swelling 448 2.5 2.5 signal
500 Localised Infection 90 2.5 2.5 signal
501 Hypersomnia 106 2.5 2.5 signal
502 Rhinorrhoea 238 2.5 2.5 signal
503 Head Discomfort 65 2.5 2.5 signal
504 Activities Of Daily Living Impaired 74 2.5 2.5 signal
505 Anaemia 703 2.5 2.5 signal
506 Skin Discolouration 169 2.5 2.5 signal
507 Nodule 48 2.5 2.5 signal
508 Myocardial Ischaemia 42 2.5 2.5 signal
509 Hair Colour Changes 46 2.5 2.5 signal
510 Hospice Care 36 2.5 2.5 signal
511 Cardiomyopathy 54 2.5 2.5 signal
512 Hypokinesia 53 2.5 2.5 signal
513 Dysgeusia 272 2.4 2.5 signal
514 Oropharyngeal Pain 337 2.4 2.5 signal
515 Cardiac Failure Congestive 295 2.4 2.5 signal
516 Dizziness 1,809 2.4 2.5 signal
517 Peripheral Coldness 50 2.4 2.4 signal
518 Dyskinesia 147 2.4 2.4 signal
519 Nervousness 190 2.4 2.4 signal
520 Fear 98 2.4 2.4 signal
521 Hyponatraemia 203 2.4 2.4 signal
522 Somnolence 726 2.4 2.5 signal
523 Fatigue 2,802 2.4 2.6 signal
524 Vision Blurred 492 2.4 2.4 signal
525 Hypertension 763 2.4 2.5 signal
526 Thirst 64 2.4 2.4 signal
527 Diplopia 93 2.4 2.4 signal
528 Hunger 48 2.4 2.4 signal
529 Tremor 592 2.4 2.4 signal
530 Sluggishness 36 2.4 2.4 signal
531 Arterial Occlusive Disease 28 2.4 2.4 signal
532 Abnormal Faeces 29 2.4 2.4 signal
533 Road Traffic Accident 148 2.4 2.4 signal
534 Nasopharyngitis 653 2.4 2.4 signal
535 Pneumonia Aspiration 88 2.4 2.4 signal
536 Acidosis 27 2.4 2.4 signal
537 Skin Ulcer 91 2.4 2.4 signal
538 Weight Increased 785 2.4 2.4 signal
539 Diarrhoea 2,265 2.4 2.5 signal
540 Viral Infection 117 2.4 2.4 signal
541 Muscle Twitching 81 2.4 2.4 signal
542 Ear Infection 93 2.4 2.4 signal
543 Bedridden 46 2.4 2.4 signal
544 Splenomegaly 41 2.4 2.4 signal
545 Procedural Complication 27 2.4 2.4 signal
546 Oxygen Saturation Decreased 195 2.3 2.4 signal
547 Hip Arthroplasty 53 2.3 2.3 signal
548 Glossodynia 78 2.3 2.3 signal
549 Abdominal Pain 811 2.3 2.4 signal
550 Colitis 131 2.3 2.3 signal
551 Lower Respiratory Tract Infection 157 2.3 2.3 signal
552 Skin Lesion 94 2.3 2.3 signal
553 Oral Discomfort 48 2.3 2.3 signal
554 Acute Respiratory Failure 66 2.3 2.3 signal
555 Breast Tenderness 26 2.3 2.3 signal
556 Palpitations 401 2.3 2.3 signal
557 Brain Fog 50 2.3 2.3 signal
558 Laboratory Test Abnormal 101 2.3 2.3 signal
559 Pseudomonas Infection 29 2.3 2.3 signal
560 Eye Discharge 35 2.3 2.3 signal
561 Bronchospasm 49 2.3 2.3 signal
562 Deformity 32 2.3 2.3 signal
563 Laryngitis 37 2.3 2.3 signal
564 Vertigo 207 2.3 2.3 signal
565 Taste Disorder 68 2.3 2.3 signal
566 Lethargy 195 2.3 2.3 signal
567 Cardiac Disorder 318 2.3 2.3 signal
568 Stomatitis 205 2.3 2.3 signal
569 Blood Creatinine Increased 221 2.3 2.3 signal
570 Liver Function Test Increased 72 2.3 2.3 signal
571 Blister 189 2.3 2.3 signal
572 Tardive Dyskinesia 96 2.3 2.3 signal
573 Amnesia 220 2.3 2.3 signal
574 Faeces Discoloured 73 2.3 2.3 signal
575 Pleural Effusion 205 2.3 2.3 signal
576 Thinking Abnormal 63 2.3 2.3 signal
577 Renal Disorder 157 2.3 2.3 signal
578 Lymphadenopathy 119 2.3 2.3 signal
579 Blood Thyroid Stimulating Hormone Increased 31 2.3 2.3 signal
580 Syncope 335 2.2 2.3 signal
581 Alopecia 658 2.2 2.3 signal
582 Cold Sweat 59 2.2 2.2 signal
583 Retching 71 2.2 2.2 signal
584 International Normalised Ratio Increased 96 2.2 2.2 signal
585 Madarosis 39 2.2 2.2 signal
586 Osteonecrosis Of Jaw 83 2.2 2.2 signal
587 Haemoglobin Decreased 342 2.2 2.2 signal
588 Mobility Decreased 238 2.2 2.2 signal
589 Renal Failure 444 2.2 2.2 signal
590 Gastrointestinal Disorder 293 2.2 2.2 signal
591 Grip Strength Decreased 29 2.2 2.2 signal
592 Dehydration 442 2.2 2.2 signal
593 Sneezing 74 2.2 2.2 signal
594 Hyperhidrosis 426 2.2 2.2 signal
595 Heart Rate Increased 327 2.2 2.2 signal
596 Headache 2,067 2.2 2.3 signal
597 Infusion Site Pain 42 2.2 2.2 signal
598 Abdominal Discomfort 548 2.2 2.2 signal
599 Blood Glucose Decreased 158 2.2 2.2 signal
600 Impaired Work Ability 70 2.2 2.2 signal
601 Speech Disorder 171 2.2 2.2 signal
602 Coagulopathy 54 2.2 2.2 signal
603 Hypercalcaemia 40 2.2 2.2 signal
604 White Blood Cell Count Decreased 351 2.2 2.2 signal
605 Feeling Abnormal 776 2.2 2.2 signal
606 Rash Pruritic 174 2.2 2.2 signal
607 Pharyngitis 40 2.2 2.2 signal
608 Pulmonary Thrombosis 35 2.2 2.2 signal
609 Clostridium Difficile Colitis 34 2.2 2.2 signal
610 Decreased Appetite 741 2.1 2.2 signal
611 Oedema 173 2.1 2.2 signal
612 Urine Output Decreased 28 2.1 2.1 signal
613 Anxiety 911 2.1 2.2 signal
614 Hallucination, Visual 67 2.1 2.1 signal
615 Knee Operation 31 2.1 2.1 signal
616 Increased Appetite 60 2.1 2.1 signal
617 Gastric Disorder 111 2.1 2.1 signal
618 Scratch 33 2.1 2.1 signal
619 Memory Impairment 438 2.1 2.2 signal
620 Fluid Overload 47 2.1 2.1 signal
621 Epistaxis 238 2.1 2.1 signal
622 Mental Status Changes 88 2.1 2.1 signal
623 Aphonia 44 2.1 2.1 signal
624 Eye Haemorrhage 42 2.1 2.1 signal
625 Eye Swelling 116 2.1 2.1 signal
626 Renal Injury 94 2.1 2.1 signal
627 Wound Infection 34 2.1 2.1 signal
628 Pain 1,924 2.1 2.2 signal
629 Dyspnoea 1,765 2.1 2.2 signal
630 Nausea 2,460 2.1 2.2 signal
631 Therapy Change 30 2.1 2.1 signal
632 Panic Attack 113 2.1 2.1 signal
633 Musculoskeletal Disorder 59 2.1 2.1 signal
634 Abdominal Pain Lower 78 2.1 2.1 signal
635 Hernia 59 2.1 2.1 signal
636 Influenza 342 2.1 2.1 signal
637 Abnormal Dreams 85 2.1 2.1 signal
638 Blood Count Abnormal 47 2.1 2.1 signal
639 Influenza Like Illness 252 2.0 2.1 signal
640 Lacrimation Increased 91 2.0 2.0 signal
641 Retinal Detachment 28 2.0 2.0 signal
642 Transfusion 32 2.0 2.0 signal
643 Intraocular Pressure Increased 39 2.0 2.0 signal
644 Loss Of Personal Independence In Daily Activities 144 2.0 2.0 signal
645 Hypoxia 106 2.0 2.0 signal
646 Wound 84 2.0 2.0 signal
647 Inappropriate Schedule Of Drug Administration 218 2.0 2.0 signal
648 Migraine 285 2.0 2.0 signal
649 Clostridium Difficile Infection 65 2.0 2.0 signal
650 Urticaria 499 2.0 2.0 signal
651 Throat Tightness 81 2.0 2.0 signal
652 Ocular Hyperaemia 140 2.0 2.0 signal
653 Spinal Pain 35 2.0 2.0 signal
654 Hypoaesthesia Oral 45 2.0 2.0 signal
655 Immunodeficiency 44 2.0 2.0 signal
656 Chills 350 2.0 2.0 signal
657 Restlessness 109 2.0 2.0 no signal
658 Glomerular Filtration Rate Decreased 36 2.0 2.0 no signal
659 Decreased Immune Responsiveness 29 2.0 2.0 no signal
660 Bone Density Decreased 94 2.0 2.0 no signal
661 Confusional State 480 2.0 2.0 no signal
662 Pruritus Generalised 65 2.0 2.0 no signal
663 Pruritus 1,119 2.0 2.0 no signal
664 Sepsis 330 2.0 2.0 no signal
665 Pharyngeal Oedema 46 2.0 2.0 no signal
666 Obesity 47 2.0 2.0 no signal
667 Cholecystitis 35 2.0 2.0 no signal
668 Swollen Tongue 92 2.0 2.0 no signal
669 Presyncope 71 2.0 2.0 no signal
670 Urosepsis 27 2.0 2.0 no signal
671 Renal Failure Acute 126 2.0 2.0 no signal
672 Orthostatic Hypotension 51 2.0 2.0 no signal
673 Lung Infection 46 2.0 2.0 no signal
674 Platelet Count Increased 38 2.0 2.0 no signal
675 Folliculitis 30 2.0 2.0 no signal
676 Device Failure 44 1.9 1.9 no signal
677 Dysarthria 109 1.9 1.9 no signal
678 Ventricular Tachycardia 48 1.9 1.9 no signal
679 Haematoma 75 1.9 1.9 no signal
680 Lower Limb Fracture 55 1.9 1.9 no signal
681 Candida Infection 48 1.9 1.9 no signal
682 Pharyngitis Streptococcal 31 1.9 1.9 no signal
683 Swelling Face 186 1.9 1.9 no signal
684 Kidney Infection 56 1.9 1.9 no signal
685 Renal Tubular Necrosis 28 1.9 1.9 no signal
686 Helicobacter Infection 29 1.9 1.9 no signal
687 Blood Bilirubin Increased 77 1.9 1.9 no signal
688 Skin Haemorrhage 41 1.9 1.9 no signal
689 Staphylococcal Infection 94 1.9 1.9 no signal
690 Eye Disorder 93 1.9 1.9 no signal
691 Pulmonary Fibrosis 54 1.9 1.9 no signal
692 Inflammation 145 1.9 1.9 no signal
693 Scab 32 1.9 1.9 no signal
694 Pneumonia 904 1.9 1.9 no signal
695 Skin Disorder 93 1.9 1.9 no signal
696 Multiple Sclerosis Relapse 193 1.9 1.9 no signal
697 Malnutrition 31 1.9 1.9 no signal
698 Choking 54 1.9 1.9 no signal
699 Product Substitution Issue 160 1.9 1.9 no signal
700 Delusion 43 1.9 1.9 no signal
701 Leukocytosis 50 1.9 1.9 no signal
702 Erythema 566 1.9 1.9 no signal
703 Pulmonary Oedema 123 1.8 1.8 no signal
704 Rash Generalised 72 1.8 1.8 no signal
705 Post Procedural Haemorrhage 32 1.8 1.8 no signal
706 Liver Disorder 121 1.8 1.8 no signal
707 Rash Macular 95 1.8 1.8 no signal
708 Tubulointerstitial Nephritis 51 1.8 1.8 no signal
709 Hypophagia 69 1.8 1.8 no signal
710 Injury 192 1.8 1.8 no signal
711 Blood Pressure Decreased 180 1.8 1.8 no signal
712 Deep Vein Thrombosis 177 1.8 1.8 no signal
713 Unevaluable Event 205 1.8 1.8 no signal
714 Eye Irritation 151 1.8 1.8 no signal
715 Hypotension 542 1.8 1.8 no signal
716 Discomfort 164 1.8 1.8 no signal
717 Eye Pruritus 89 1.8 1.8 no signal
718 Blindness Unilateral 38 1.8 1.8 no signal
719 Electrolyte Imbalance 31 1.8 1.8 no signal
720 Asthma 302 1.8 1.8 no signal
721 Disorientation 107 1.8 1.8 no signal
722 Infection 387 1.8 1.8 no signal
723 Aphasia 81 1.8 1.8 no signal
724 Drug Hypersensitivity 519 1.8 1.8 no signal
725 Rheumatoid Arthritis 302 1.8 1.8 no signal
726 Tendon Rupture 33 1.8 1.8 no signal
727 Movement Disorder 86 1.8 1.8 no signal
728 Sleep Disorder Due To A General Medical Condition 43 1.8 1.8 no signal
729 Feeding Disorder 53 1.8 1.8 no signal
730 Dementia 74 1.8 1.8 no signal
731 Paranoia 46 1.8 1.8 no signal
732 Anger 90 1.8 1.8 no signal
733 Mental Impairment 64 1.8 1.8 no signal
734 Hypokalaemia 121 1.8 1.8 no signal
735 Acute Myocardial Infarction 78 1.8 1.8 no signal
736 Ejection Fraction Decreased 41 1.8 1.8 no signal
737 Gait Inability 87 1.8 1.8 no signal
738 Blood Pressure Abnormal 52 1.8 1.8 no signal
739 Surgery 152 1.8 1.8 no signal
740 Pulmonary Embolism 250 1.8 1.8 no signal
741 Drug Intolerance 252 1.8 1.8 no signal
742 Apathy 38 1.8 1.8 no signal
743 Autoimmune Disorder 25 1.8 1.8 no signal
744 Sinus Tachycardia 37 1.8 1.8 no signal
745 Vomiting 1,222 1.7 1.8 no signal
746 Crying 95 1.7 1.8 no signal
747 Salivary Hypersecretion 26 1.7 1.7 no signal
748 Generalised Oedema 32 1.7 1.7 no signal
749 Hallucination 194 1.7 1.7 no signal
750 Rash Papular 58 1.7 1.7 no signal
751 Loss Of Consciousness 330 1.7 1.7 no signal
752 Oral Herpes 50 1.7 1.7 no signal
753 Anhedonia 68 1.7 1.7 no signal
754 Deafness 67 1.7 1.7 no signal
755 Lung Disorder 125 1.7 1.7 no signal
756 Blood Glucose Fluctuation 28 1.7 1.7 no signal
757 Respiratory Tract Infection 66 1.7 1.7 no signal
758 Pericardial Effusion 58 1.7 1.7 no signal
759 Visual Acuity Reduced 84 1.7 1.7 no signal
760 Drug Effect Decreased 137 1.7 1.7 no signal
761 Neoplasm Progression 88 1.7 1.7 no signal
762 Bone Loss 38 1.7 1.7 no signal
763 Gastrointestinal Haemorrhage 210 1.7 1.7 no signal
764 Photosensitivity Reaction 41 1.7 1.7 no signal
765 Condition Aggravated 749 1.7 1.7 no signal
766 Motor Dysfunction 25 1.7 1.7 no signal
767 Gastric Ulcer 47 1.7 1.7 no signal
768 Therapy Interrupted 170 1.7 1.7 no signal
769 Personality Change 23 1.7 1.7 no signal
770 Hypoglycaemia 119 1.6 1.6 no signal
771 Emotional Disorder 76 1.6 1.6 no signal
772 Abscess 39 1.6 1.6 no signal
773 Device Occlusion 34 1.6 1.6 no signal
774 Hypoacusis 105 1.6 1.6 no signal
775 Malaise 1,071 1.6 1.7 no signal
776 Convulsion 141 1.6 1.6 no signal
777 Mouth Ulceration 51 1.6 1.6 no signal
778 Poor Venous Access 25 1.6 1.6 no signal
779 Colitis Ulcerative 108 1.6 1.6 no signal
780 Product Dose Omission In Error 65 1.6 1.6 no signal
781 Haematuria 83 1.6 1.6 no signal
782 Nightmare 84 1.6 1.6 no signal
783 Colon Cancer 36 1.6 1.6 no signal
784 Hemiparesis 41 1.6 1.6 no signal
785 Dry Skin 316 1.6 1.6 no signal
786 Metastases To Liver 42 1.6 1.6 no signal
787 Intentional Product Misuse 207 1.6 1.6 no signal
788 Prostatic Specific Antigen Increased 33 1.6 1.6 no signal
789 Hereditary Angioedema 25 1.6 1.6 no signal
790 Lip Swelling 79 1.6 1.6 no signal
791 Immune System Disorder 31 1.6 1.6 no signal
792 Treatment Noncompliance 128 1.6 1.6 no signal
793 Rash 1,020 1.6 1.6 no signal
794 Accident 28 1.6 1.6 no signal
795 Hyperthyroidism 34 1.6 1.6 no signal
796 Anosmia 34 1.6 1.6 no signal
797 Conjunctivitis 43 1.6 1.6 no signal
798 Libido Decreased 29 1.6 1.6 no signal
799 Psoriatic Arthropathy 94 1.6 1.6 no signal
800 Pyrexia 808 1.6 1.6 no signal
801 Disturbance In Attention 126 1.6 1.6 no signal
802 Rash Erythematous 109 1.6 1.6 no signal
803 Lymphocyte Count Decreased 41 1.6 1.6 no signal
804 Mood Altered 63 1.6 1.6 no signal
805 Spinal Operation 28 1.6 1.6 no signal
806 Irritability 139 1.5 1.6 no signal
807 Quality Of Life Decreased 31 1.5 1.5 no signal
808 Visual Impairment 283 1.5 1.5 no signal
809 Blood Glucose Increased 434 1.5 1.5 no signal
810 Platelet Count Decreased 244 1.5 1.5 no signal
811 Contraindicated Product Administered 69 1.5 1.5 no signal
812 Injection Site Nodule 25 1.5 1.5 no signal
813 Dermatitis 47 1.5 1.5 no signal
814 Ataxia 27 1.5 1.5 no signal
815 Skin Exfoliation 188 1.5 1.5 no signal
816 Eyelid Ptosis 23 1.5 1.5 no signal
817 Blindness 92 1.5 1.5 no signal
818 Mood Swings 72 1.5 1.5 no signal
819 Upper Gastrointestinal Haemorrhage 38 1.5 1.5 no signal
820 Hepatic Encephalopathy 21 1.5 1.5 no signal
821 Hypersensitivity 416 1.5 1.5 no signal
822 Myocardial Infarction 394 1.5 1.5 no signal
823 Drug Dose Omission 375 1.5 1.5 no signal
824 Hypomagnesaemia 31 1.5 1.5 no signal
825 Arrhythmia 106 1.5 1.5 no signal
826 Cardiovascular Disorder 57 1.5 1.5 no signal
827 Urinary Retention 74 1.5 1.5 no signal
828 Blood Creatine Phosphokinase Increased 65 1.5 1.5 no signal
829 Therapeutic Product Effect Incomplete 157 1.5 1.5 no signal
830 Injection Site Haemorrhage 176 1.5 1.5 no signal
831 Intestinal Obstruction 83 1.5 1.5 no signal
832 Haematemesis 56 1.5 1.5 no signal
833 Cerebrovascular Accident 372 1.5 1.5 no signal
834 Skin Fissures 41 1.5 1.5 no signal
835 Neoplasm 25 1.5 1.5 no signal
836 Gamma-glutamyltransferase Increased 48 1.5 1.5 no signal
837 Pelvic Pain 39 1.4 1.4 no signal
838 Breast Cancer Metastatic 23 1.4 1.4 no signal
839 Sexual Dysfunction 25 1.4 1.4 no signal
840 Metastases To Bone 35 1.4 1.4 no signal
841 Incorrect Drug Administration Duration 61 1.4 1.4 no signal
842 Agitation 157 1.4 1.4 no signal
843 Respiratory Failure 155 1.4 1.4 no signal
844 Prescribed Overdose 41 1.4 1.4 no signal
845 Acute Kidney Injury 322 1.4 1.4 no signal
846 Prescribed Underdose 42 1.4 1.4 no signal
847 Sars-cov-2 Test Positive 28 1.4 1.4 no signal
848 Haemorrhage 219 1.4 1.4 no signal
849 Diabetes Mellitus Inadequate Control 37 1.4 1.4 no signal
850 Metastases To Lung 24 1.4 1.4 no signal
851 Device Related Infection 32 1.4 1.4 no signal
852 Product Dose Omission Issue 589 1.4 1.4 no signal
853 Product Use Complaint 32 1.4 1.4 no signal
854 Covid-19 365 1.4 1.4 no signal
855 Lymphopenia 29 1.4 1.4 no signal
856 Parkinsonism 20 1.4 1.4 no signal
857 Synovitis 37 1.4 1.4 no signal
858 Suicidal Ideation 187 1.4 1.4 no signal
859 Melaena 45 1.4 1.4 no signal
860 General Physical Health Deterioration 234 1.4 1.4 no signal
861 Inability To Afford Medication 20 1.4 1.4 no signal
862 Hepatitis 52 1.4 1.4 no signal
863 Grand Mal Convulsion 19 1.4 1.4 no signal
864 Unresponsive To Stimuli 52 1.4 1.4 no signal
865 No Therapeutic Response 25 1.4 1.4 no signal
866 Covid-19 Pneumonia 24 1.4 1.4 no signal
867 Impaired Quality Of Life 29 1.4 1.4 no signal
868 Tooth Loss 42 1.3 1.3 no signal
869 Mania 33 1.3 1.3 no signal
870 Fracture 38 1.3 1.3 no signal
871 Therapeutic Response Decreased 121 1.3 1.3 no signal
872 Multi-organ Failure 35 1.3 1.3 no signal
873 Illness 200 1.3 1.3 no signal
874 Pericarditis 33 1.3 1.3 no signal
875 Mental Disorder 86 1.3 1.3 no signal
876 Drug Administered At Inappropriate Site 21 1.3 1.3 no signal
877 Osteonecrosis 65 1.3 1.3 no signal
878 Drug Level Decreased 20 1.3 1.3 no signal
879 Drug Toxicity 27 1.3 1.3 no signal
880 Fistula 22 1.3 1.3 no signal
881 Disease Progression 230 1.3 1.3 no signal
882 Ill-defined Disorder 118 1.3 1.3 no signal
883 Transaminases Increased 43 1.3 1.3 no signal
884 Coeliac Disease 19 1.3 1.3 no signal
885 Adverse Drug Reaction 173 1.3 1.3 no signal
886 Multiple Fractures 32 1.3 1.3 no signal
887 Drug Administration Error 60 1.3 1.3 no signal
888 Jaundice 52 1.3 1.3 no signal
889 Product Odour Abnormal 20 1.3 1.3 no signal
890 Muscle Rigidity 23 1.3 1.3 no signal
891 Proteinuria 36 1.3 1.3 no signal
892 Leukopenia 95 1.3 1.3 no signal
893 Cyanosis 30 1.3 1.3 no signal
894 Intentional Dose Omission 52 1.3 1.3 no signal
895 Injection Site Erythema 234 1.3 1.3 no signal
896 Intentional Drug Misuse 40 1.3 1.3 no signal
897 Application Site Rash 26 1.3 1.3 no signal
898 Encephalopathy 46 1.3 1.3 no signal
899 Intestinal Perforation 21 1.3 1.3 no signal
900 Tachycardia 166 1.3 1.3 no signal
901 Pancreatitis 98 1.2 1.2 no signal
902 Injection Site Bruising 146 1.2 1.2 no signal
903 Polyneuropathy 22 1.2 1.2 no signal
904 Hyperglycaemia 67 1.2 1.2 no signal
905 Hyperbilirubinaemia 19 1.2 1.2 no signal
906 Injection Site Haematoma 27 1.2 1.2 no signal
907 Renal Impairment 154 1.2 1.2 no signal
908 Palmar-plantar Erythrodysaesthesia Syndrome 43 1.2 1.2 no signal
909 Hyperkalaemia 64 1.2 1.2 no signal
910 Product Packaging Issue 17 1.2 1.2 no signal
911 Abnormal Behaviour 73 1.2 1.2 no signal
912 Hallucination, Auditory 29 1.2 1.2 no signal
913 Drug Effect Incomplete 67 1.2 1.2 no signal
914 Subdural Haematoma 26 1.2 1.2 no signal
915 Paralysis 26 1.2 1.2 no signal
916 Skin Irritation 83 1.2 1.2 no signal
917 Anaphylactic Reaction 99 1.2 1.2 no signal
918 Metastases To Central Nervous System 23 1.2 1.2 no signal
919 Brain Injury 18 1.2 1.2 no signal
920 Delirium 62 1.2 1.2 no signal
921 Pain Of Skin 48 1.2 1.2 no signal
922 Application Site Pain 39 1.2 1.2 no signal
923 Application Site Pruritus 40 1.2 1.2 no signal
924 Psychotic Disorder 52 1.2 1.2 no signal
925 Hepatotoxicity 39 1.2 1.2 no signal
926 Euphoric Mood 18 1.2 1.2 no signal
927 Psoriasis 228 1.2 1.2 no signal
928 Injection Site Pruritus 115 1.2 1.2 no signal
929 Myelodysplastic Syndrome 25 1.2 1.2 no signal
930 Nervous System Disorder 54 1.2 1.2 no signal
931 Hepatic Failure 52 1.2 1.2 no signal
932 Acne 131 1.2 1.2 no signal
933 Ileus 21 1.1 1.1 no signal
934 Product Physical Issue 34 1.1 1.1 no signal
935 C-reactive Protein Increased 62 1.1 1.1 no signal
936 Bacteraemia 20 1.1 1.1 no signal
937 Injection Site Induration 22 1.1 1.1 no signal
938 Leukaemia 16 1.1 1.1 no signal
939 Hypotonia 17 1.1 1.1 no signal
940 Injection Site Discolouration 21 1.1 1.1 no signal
941 Drug Dispensing Error 26 1.1 1.1 no signal
942 Brain Oedema 21 1.1 1.1 no signal
943 Central Nervous System Lesion 23 1.1 1.1 no signal
944 Injection Site Irritation 21 1.1 1.1 no signal
945 Internal Haemorrhage 19 1.1 1.1 no signal
946 Product Use Issue 310 1.1 1.1 no signal
947 Bradycardia 88 1.1 1.1 no signal
948 Product Administration Error 33 1.1 1.1 no signal
949 Pancytopenia 92 1.1 1.1 no signal
950 Pallor 45 1.1 1.1 no signal
951 Sedation 43 1.1 1.1 no signal
952 Pulmonary Arterial Hypertension 24 1.1 1.1 no signal
953 Injection Site Rash 50 1.1 1.1 no signal
954 Vaginal Haemorrhage 70 1.1 1.1 no signal
955 Thrombocytopenia 183 1.1 1.1 no signal
956 Therapy Non-responder 73 1.1 1.1 no signal
957 Plasma Cell Myeloma 64 1.1 1.1 no signal
958 Therapeutic Response Shortened 52 1.1 1.1 no signal
959 Eczema 82 1.1 1.1 no signal
960 Wrong Technique In Drug Usage Process 60 1.1 1.1 no signal
961 Eyelid Oedema 19 1.1 1.1 no signal
962 Therapeutic Product Effect Decreased 72 1.1 1.1 no signal
963 Blood Glucose Abnormal 30 1.1 1.1 no signal
964 Drug Ineffective 2,132 1.1 1.1 no signal
965 Underdose 118 1.1 1.1 no signal
966 Injection Site Mass 59 1.1 1.1 no signal
967 Application Site Erythema 42 1.1 1.1 no signal
968 Respiratory Distress 44 1.1 1.1 no signal
969 Complication Associated With Device 21 1.1 1.1 no signal
970 Product Quality Issue 214 1.1 1.1 no signal
971 Inappropriate Antidiuretic Hormone Secretion 16 1.1 1.1 no signal
972 Blood Lactate Dehydrogenase Increased 25 1.1 1.1 no signal
973 Injection Site Urticaria 38 1.1 1.1 no signal
974 Psychomotor Hyperactivity 26 1.0 1.0 no signal
975 Uveitis 21 1.0 1.0 no signal
976 Lymphoma 24 1.0 1.0 no signal
977 Vasculitis 18 1.0 1.0 no signal
978 Skin Burning Sensation 109 1.0 1.0 no signal
979 Coma 73 1.0 1.0 no signal
980 Breast Cancer Female 41 1.0 1.0 no signal
981 Drug Interaction 241 1.0 1.0 no signal
982 Systemic Lupus Erythematosus 53 1.0 1.0 no signal
983 Adverse Event 138 1.0 1.0 no signal
984 Mydriasis 19 1.0 1.0 no signal
985 Pneumonitis 40 1.0 1.0 no signal
986 Dialysis 21 1.0 1.0 no signal
987 Product Packaging Quantity Issue 16 1.0 1.0 no signal
988 Disability 29 1.0 1.0 no signal
989 Rhabdomyolysis 61 1.0 1.0 no signal
990 Akathisia 20 1.0 1.0 no signal
991 Emotional Distress 178 1.0 1.0 no signal
992 Pharyngeal Swelling 14 1.0 1.0 no signal
993 Product Dose Omission 96 1.0 1.0 no signal
994 Inappropriate Schedule Of Product Administration 256 1.0 1.0 no signal
995 Affect Lability 14 1.0 1.0 no signal
996 Dermatitis Allergic 18 1.0 1.0 no signal
997 Intentional Product Use Issue 127 1.0 1.0 no signal
998 Seizure 165 1.0 1.0 no signal
999 Disease Recurrence 68 1.0 1.0 no signal
1000 Off Label Use 1,235 1.0 1.0 no signal
1001 Inflammatory Bowel Disease 14 1.0 1.0 no signal
1002 Expired Product Administered 47 0.9 0.9 no signal
1003 Disseminated Intravascular Coagulation 20 0.9 0.9 no signal
1004 Aggression 71 0.9 0.9 no signal
1005 Acute Respiratory Distress Syndrome 25 0.9 0.9 no signal
1006 Product Taste Abnormal 19 0.9 0.9 no signal
1007 Ovarian Cancer 13 0.9 0.9 no signal
1008 Cerebral Haemorrhage 50 0.9 0.9 no signal
1009 Injection Site Pain 422 0.9 0.9 no signal
1010 Product Availability Issue 31 0.9 0.9 no signal
1011 Mucosal Inflammation 36 0.9 0.9 no signal
1012 Withdrawal Syndrome 58 0.9 0.9 no signal
1013 Subarachnoid Haemorrhage 14 0.9 0.9 no signal
1014 Menorrhagia 27 0.9 0.9 no signal
1015 Pancreatitis Acute 30 0.9 0.9 no signal
1016 Injection Site Swelling 101 0.9 0.9 no signal
1017 Hospitalisation 203 0.9 0.9 no signal
1018 Injection Site Reaction 91 0.9 0.9 no signal
1019 Breast Cancer 124 0.9 0.9 no signal
1020 Incorrect Dose Administered 296 0.9 0.9 no signal
1021 Septic Shock 56 0.9 0.9 no signal
1022 Gastric Haemorrhage 15 0.9 0.9 no signal
1023 Ischaemic Stroke 23 0.9 0.9 no signal
1024 Diarrhoea Haemorrhagic 12 0.9 0.9 no signal
1025 Drug Effect Less Than Expected 18 0.9 0.9 no signal
1026 Eye Inflammation 12 0.9 0.9 no signal
1027 Metrorrhagia 22 0.9 0.9 no signal
1028 Cerebral Infarction 31 0.8 0.8 no signal
1029 Injection Site Discomfort 13 0.8 0.8 no signal
1030 Hypertensive Crisis 14 0.8 0.8 no signal
1031 Febrile Neutropenia 83 0.8 0.8 no signal
1032 Medication Error 69 0.8 0.8 no signal
1033 Product Use In Unapproved Indication 300 0.8 0.8 no signal
1034 Dermatitis Atopic 61 0.8 0.8 no signal
1035 Cardiac Arrest 101 0.8 0.8 no signal
1036 Hypocalcaemia 23 0.8 0.8 no signal
1037 Product Administered At Inappropriate Site 22 0.8 0.8 no signal
1038 Skin Reaction 17 0.8 0.8 no signal
1039 Haemorrhage Intracranial 18 0.8 0.8 no signal
1040 Electrocardiogram Qt Prolonged 43 0.8 0.8 no signal
1041 Needle Issue 34 0.8 0.8 no signal
1042 Drug Ineffective For Unapproved Indication 66 0.8 0.8 no signal
1043 Hypothermia 12 0.8 0.8 no signal
1044 Bone Marrow Failure 24 0.8 0.8 no signal
1045 Cytopenia 14 0.8 0.8 no signal
1046 Neutropenia 156 0.8 0.8 no signal
1047 Ankylosing Spondylitis 15 0.8 0.8 no signal
1048 Respiratory Arrest 32 0.8 0.8 no signal
1049 Depressed Level Of Consciousness 45 0.8 0.8 no signal
1050 Neoplasm Malignant 75 0.8 0.8 no signal
1051 Accidental Overdose 41 0.8 0.8 no signal
1052 Injection Site Extravasation 14 0.8 0.8 no signal
1053 Liver Injury 27 0.7 0.7 no signal
1054 Tachypnoea 15 0.7 0.7 no signal
1055 Neutrophil Count Decreased 44 0.7 0.7 no signal
1056 Product Prescribing Issue 22 0.7 0.7 no signal
1057 Cardiac Failure 85 0.7 0.7 no signal
1058 Application Site Irritation 13 0.7 0.7 no signal
1059 Product Adhesion Issue 37 0.7 0.7 no signal
1060 Sudden Death 11 0.7 0.7 no signal
1061 Cardio-respiratory Arrest 43 0.7 0.7 no signal
1062 Device Dislocation 44 0.7 0.7 no signal
1063 Product Dispensing Error 22 0.7 0.7 no signal
1064 Neuroleptic Malignant Syndrome 12 0.7 0.7 no signal
1065 Myoclonus 12 0.7 0.7 no signal
1066 Wrong Technique In Product Usage Process 201 0.7 0.7 no signal
1067 Stevens-johnson Syndrome 22 0.7 0.7 no signal
1068 Hepatitis C 12 0.7 0.7 no signal
1069 Adverse Reaction 13 0.7 0.7 no signal
1070 Device Issue 85 0.7 0.7 no signal
1071 Malignant Neoplasm Progression 99 0.7 0.7 no signal
1072 Rebound Effect 11 0.7 0.6 no signal
1073 Pemphigus 12 0.6 0.6 no signal
1074 Extrapyramidal Disorder 24 0.6 0.6 no signal
1075 Acute Hepatic Failure 13 0.6 0.6 no signal
1076 Extra Dose Administered 38 0.6 0.6 no signal
1077 Face Oedema 16 0.6 0.6 no signal
1078 Drug Prescribing Error 18 0.6 0.6 no signal
1079 Neurotoxicity 16 0.6 0.6 no signal
1080 Peritonitis 19 0.6 0.6 no signal
1081 Device Malfunction 61 0.6 0.6 no signal
1082 Drug Level Increased 15 0.6 0.6 no signal
1083 Rash Maculo-papular 20 0.6 0.6 no signal
1084 Incorrect Product Storage 12 0.6 0.6 no signal
1085 Death 764 0.6 0.6 no signal
1086 Shock 20 0.6 0.6 no signal
1087 Dystonia 17 0.6 0.6 no signal
1088 Brain Neoplasm 8 0.6 0.6 no signal
1089 Exposure During Pregnancy 54 0.6 0.6 no signal
1090 Device Defective 14 0.6 0.6 no signal
1091 Therapy Partial Responder 13 0.6 0.6 no signal
1092 Skeletal Injury 9 0.6 0.6 no signal
1093 Anaphylactic Shock 22 0.6 0.6 no signal
1094 Drug Withdrawal Syndrome 76 0.6 0.6 no signal
1095 Lung Neoplasm Malignant 35 0.6 0.6 no signal
1096 Product Prescribing Error 20 0.6 0.6 no signal
1097 Dysmenorrhoea 11 0.6 0.6 no signal
1098 Pregnancy 17 0.6 0.6 no signal
1099 Injection Site Warmth 17 0.6 0.6 no signal
1100 Interstitial Lung Disease 39 0.5 0.5 no signal
1101 Amenorrhoea 13 0.5 0.5 no signal
1102 Drug-induced Liver Injury 24 0.5 0.5 no signal
1103 Acute Myeloid Leukaemia 12 0.5 0.5 no signal
1104 Abortion Spontaneous 31 0.5 0.5 no signal
1105 Breast Cancer Stage I 7 0.5 0.5 no signal
1106 Thyroid Cancer 9 0.5 0.5 no signal
1107 Toxic Epidermal Necrolysis 11 0.5 0.5 no signal
1108 Prostate Cancer 59 0.5 0.5 no signal
1109 Circumstance Or Information Capable Of Leading To Medication Error 24 0.5 0.5 no signal
1110 Angioedema 31 0.5 0.5 no signal
1111 Metabolic Acidosis 22 0.5 0.5 no signal
1112 Suicide Attempt 42 0.5 0.5 no signal
1113 Incorrect Product Administration Duration 14 0.5 0.5 no signal
1114 Hand Deformity 9 0.5 0.5 no signal
1115 Cholestasis 13 0.5 0.5 no signal
1116 Overdose 146 0.5 0.4 no signal
1117 Schizophrenia 8 0.4 0.4 no signal
1118 Altered State Of Consciousness 14 0.4 0.4 no signal
1119 Injury Associated With Device 13 0.4 0.4 no signal
1120 Circulatory Collapse 11 0.4 0.4 no signal
1121 Menstruation Irregular 17 0.4 0.4 no signal
1122 Device Breakage 25 0.4 0.4 no signal
1123 Posterior Reversible Encephalopathy Syndrome 6 0.4 0.4 no signal
1124 Pancreatic Carcinoma 18 0.4 0.4 no signal
1125 Status Epilepticus 7 0.4 0.4 no signal
1126 Maternal Exposure During Pregnancy 54 0.4 0.4 no signal
1127 Product Complaint 15 0.4 0.4 no signal
1128 Caesarean Section 7 0.4 0.4 no signal
1129 Menstruation Delayed 6 0.4 0.4 no signal
1130 Exposure Via Skin Contact 13 0.4 0.4 no signal
1131 Respiratory Depression 7 0.4 0.4 no signal
1132 Drug Eruption 10 0.4 0.4 no signal
1133 Device Leakage 24 0.4 0.4 no signal
1134 Premature Baby 17 0.4 0.4 no signal
1135 Diabetic Ketoacidosis 13 0.4 0.4 no signal
1136 Hepatic Function Abnormal 20 0.4 0.4 no signal
1137 Erythema Multiforme 5 0.4 0.4 no signal
1138 Toxicity To Various Agents 90 0.4 0.4 no signal
1139 Device Use Issue 9 0.3 0.3 no signal
1140 Incorrect Dose Administered By Device 13 0.3 0.3 no signal
1141 Gynaecomastia 16 0.3 0.3 no signal
1142 Wrong Technique In Device Usage Process 23 0.3 0.3 no signal
1143 Treatment Failure 41 0.3 0.3 no signal
1144 Peritonitis Bacterial 5 0.3 0.3 no signal
1145 Poor Quality Product Administered 5 0.3 0.3 no signal
1146 Generalised Tonic-clonic Seizure 8 0.3 0.3 no signal
1147 Product Preparation Error 10 0.3 0.3 no signal
1148 Poisoning 6 0.3 0.3 no signal
1149 Cytokine Release Syndrome 9 0.3 0.3 no signal
1150 Syringe Issue 8 0.3 0.3 no signal
1151 Accidental Exposure To Product 45 0.3 0.3 no signal
1152 Sickle Cell Anaemia With Crisis 7 0.3 0.3 no signal
1153 Myocarditis 5 0.3 0.3 no signal
1154 Incorrect Route Of Drug Administration 16 0.3 0.3 no signal
1155 Bladder Cancer 26 0.3 0.3 no signal
1156 Epilepsy 13 0.3 0.3 no signal
1157 Hepatocellular Injury 6 0.3 0.3 no signal
1158 Abnormal Weight Gain 5 0.3 0.3 no signal
1159 Toxic Skin Eruption 4 0.3 0.3 no signal
1160 No Adverse Event 70 0.3 0.3 no signal
1161 Tuberculosis 5 0.3 0.3 no signal
1162 Foetal Exposure During Pregnancy 31 0.3 0.3 no signal
1163 Device Difficult To Use 25 0.3 0.3 no signal
1164 Premature Delivery 6 0.3 0.3 no signal
1165 Lactic Acidosis 12 0.3 0.3 no signal
1166 Serotonin Syndrome 7 0.2 0.2 no signal
1167 Cytomegalovirus Infection 6 0.2 0.2 no signal
1168 Nephropathy Toxic 4 0.2 0.2 no signal
1169 Drug Exposure During Pregnancy 12 0.2 0.2 no signal
1170 Intentional Self-injury 7 0.2 0.2 no signal
1171 Renal Cancer 16 0.2 0.2 no signal
1172 Hepatic Cancer 8 0.2 0.2 no signal
1173 Agranulocytosis 6 0.2 0.2 no signal
1174 Abortion Induced 3 0.2 0.2 no signal
1175 Gastric Cancer 8 0.2 0.2 no signal
1176 Device Delivery System Issue 8 0.2 0.2 no signal
1177 Product Storage Error 24 0.2 0.2 no signal
1178 Meningioma 4 0.2 0.2 no signal
1179 Device Use Error 9 0.2 0.2 no signal
1180 Completed Suicide 22 0.2 0.2 no signal
1181 Device Deployment Issue 3 0.2 0.2 no signal
1182 Drug Dependence 39 0.2 0.2 no signal
1183 Drug Effective For Unapproved Indication 7 0.2 0.2 no signal
1184 Complication Of Device Removal 4 0.2 0.2 no signal
1185 Intentional Overdose 15 0.2 0.2 no signal
1186 Drug Reaction With Eosinophilia And Systemic Symptoms 6 0.2 0.2 no signal
1187 Oesophageal Carcinoma 7 0.2 0.2 no signal
1188 Accidental Underdose 3 0.1 0.1 no signal
1189 Device Expulsion 13 0.1 0.1 no signal
1190 Drug Dose Omission By Device 13 0.1 0.1 no signal
1191 Complication Of Device Insertion 3 0.1 0.1 no signal
1192 Drug Abuse 13 0.1 0.1 no signal
1193 Dependence 3 0.0 0.0 no signal