OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Voxelotor

708 flagged reaction(s) · 53,272 total co-reports · max PRR 2,377.3
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Sickle Cell Anaemia With Crisis 11,218 2,377.3 4,782.7 signal
2 Acute Chest Syndrome 391 766.2 779.9 signal
3 Sickle Cell Disease 174 576.0 580.5 signal
4 Double Heterozygous Sickling Disorders 3 556.2 556.2 signal
5 Exchange Blood Transfusion 4 309.0 309.0 signal
6 Retinopathy Sickle Cell 3 185.4 185.4 signal
7 Hypersplenism 77 174.1 174.7 signal
8 Delayed Haemolytic Transfusion Reaction 5 85.8 85.8 signal
9 Reticulocyte Count Abnormal 8 71.3 71.3 signal
10 Pharmacophobia 5 63.5 63.5 signal
11 Abdominal Symptom 50 63.2 63.4 signal
12 Emergency Care 125 41.2 41.5 signal
13 Sickle Cell Anaemia 26 39.1 39.1 signal
14 Disease Complication 127 26.7 26.8 signal
15 Reticulocytopenia 4 26.7 26.7 signal
16 Priapism 91 25.3 25.4 signal
17 Reticulocyte Count Increased 20 23.7 23.8 signal
18 Intentional Product Misuse To Child 3 23.4 23.4 signal
19 Coronavirus Infection 152 21.9 22.0 signal
20 Expulsion Of Medication 11 21.2 21.2 signal
21 Therapy Cessation 1,040 19.5 20.4 signal
22 Product Use Complaint 298 18.4 18.7 signal
23 Haemoglobin Increased 86 18.3 18.4 signal
24 Arteriovenous Fistula Operation 5 17.7 17.7 signal
25 Product Dose Omission Issue 5,172 17.4 22.3 signal
26 Blood Bilirubin Decreased 11 17.0 17.0 signal
27 Infusion 7 16.2 16.2 signal
28 Central Venous Catheter Removal 7 14.1 14.1 signal
29 Cholelithotomy 3 13.2 13.2 signal
30 Insurance Issue 201 12.9 13.0 signal
31 Therapy Interrupted 900 12.4 12.9 signal
32 Bone Infarction 6 12.4 12.4 signal
33 Haemoglobin Abnormal 82 12.2 12.2 signal
34 Bone Marrow Transplant 24 12.1 12.1 signal
35 Nail Pigmentation 3 11.8 11.8 signal
36 Discontinued Product Administered 4 11.7 11.7 signal
37 Adenotonsillectomy 3 11.5 11.5 signal
38 Tooth Impacted 5 10.2 10.2 signal
39 Medical Induction Of Coma 4 9.0 9.0 signal
40 Hepatic Enzyme Decreased 4 8.5 8.5 signal
41 Product Size Issue 47 8.4 8.4 signal
42 Faeces Soft 58 7.6 7.6 signal
43 Haemochromatosis 7 7.2 7.2 signal
44 Central Venous Catheterisation 23 7.2 7.2 signal
45 Blood Lactate Dehydrogenase Abnormal 5 7.0 7.0 signal
46 Iron Overload 8 7.0 7.0 signal
47 Haemoglobin Decreased 753 6.9 7.1 signal
48 Haematocrit Abnormal 9 6.9 6.9 signal
49 Blood Iron Increased 13 6.5 6.5 signal
50 Splenectomy 8 6.5 6.5 signal
51 Therapy Non-responder 295 6.3 6.3 signal
52 Drainage 3 6.0 6.0 signal
53 Medical Procedure 10 5.8 5.8 signal
54 Abdominal Discomfort 969 5.5 5.7 signal
55 Abdominal Pain Upper 1,171 5.4 5.6 signal
56 Transfusion 59 5.3 5.3 signal
57 Endoscopy 3 4.8 4.8 signal
58 Diarrhoea 3,187 4.7 5.3 signal
59 Nail Discolouration 19 4.6 4.6 signal
60 Vaccination Complication 4 4.6 4.6 signal
61 Tonsillectomy 8 4.5 4.5 signal
62 Blood Bilirubin Abnormal 6 4.5 4.5 signal
63 Transfusion Reaction 4 4.3 4.3 signal
64 Scleral Discolouration 3 4.3 4.3 signal
65 Skin Ulcer 114 4.2 4.2 signal
66 Ocular Icterus 19 4.1 4.1 signal
67 Thrombocytosis 16 4.1 4.1 signal
68 Painful Erection 3 4.1 4.1 signal
69 Product Administration Interrupted 33 4.1 4.1 signal
70 Full Blood Count Increased 5 3.9 3.9 signal
71 Eye Colour Change 4 3.7 3.7 signal
72 Wisdom Teeth Removal 5 3.6 3.6 signal
73 Osteonecrosis 124 3.5 3.5 signal
74 Infected Skin Ulcer 7 3.5 3.5 signal
75 Oxygen Therapy 6 3.5 3.5 signal
76 Product Dose Omission In Error 98 3.4 3.5 signal
77 Colonoscopy 8 3.4 3.4 signal
78 Hip Surgery 19 3.4 3.4 signal
79 Spleen Disorder 6 3.3 3.3 signal
80 Full Blood Count Abnormal 37 3.3 3.3 signal
81 Alanine Aminotransferase Abnormal 7 3.1 3.1 signal
82 Epigastric Discomfort 13 3.1 3.1 signal
83 Aspartate Aminotransferase Abnormal 5 3.1 3.1 signal
84 Wrong Dose 8 3.1 3.1 signal
85 Post-acute Covid-19 Syndrome 4 3.0 3.0 no signal
86 Treatment Noncompliance 175 3.0 3.1 signal
87 Product After Taste 3 3.0 3.0 no signal
88 Frequent Bowel Movements 86 3.0 3.0 signal
89 Intentional Product Misuse 277 3.0 3.0 signal
90 Sars-cov-2 Test Positive 40 2.8 2.8 signal
91 Tonsillar Hypertrophy 5 2.8 2.8 signal
92 Pulmonary Hypertension 61 2.7 2.8 signal
93 Trichorrhexis 8 2.7 2.7 signal
94 Off Label Use 2,417 2.6 2.8 signal
95 Gastrointestinal Tract Irritation 3 2.6 2.6 no signal
96 Headache 1,691 2.5 2.7 signal
97 Abdominal Pain 627 2.5 2.6 signal
98 Energy Increased 16 2.5 2.5 signal
99 Platelet Count Increased 35 2.5 2.5 signal
100 Mouth Injury 4 2.5 2.5 no signal
101 Hip Arthroplasty 39 2.4 2.4 signal
102 Cholelithiasis 84 2.4 2.4 signal
103 Nausea 2,016 2.4 2.5 signal
104 Gallbladder Operation 10 2.3 2.3 signal
105 Dental Operation 6 2.3 2.3 no signal
106 Hepatic Enzyme Abnormal 12 2.3 2.3 signal
107 Gastrointestinal Tube Insertion 6 2.3 2.3 no signal
108 Dialysis 34 2.3 2.3 signal
109 Rhinovirus Infection 9 2.2 2.2 signal
110 Intentional Dose Omission 64 2.2 2.2 signal
111 Haemolysis 18 2.2 2.2 signal
112 Embolism Venous 7 2.2 2.2 no signal
113 Product Dose Omission 151 2.1 2.2 signal
114 Shoulder Arthroplasty 6 2.1 2.1 no signal
115 Viral Infection 74 2.1 2.1 signal
116 Infectious Mononucleosis 5 2.1 2.1 no signal
117 Skin Depigmentation 3 2.1 2.1 no signal
118 Rash Pruritic 117 2.0 2.0 signal
119 Oral Surgery 5 2.0 2.0 no signal
120 Intensive Care 3 2.0 2.0 no signal
121 Endotracheal Intubation 6 2.0 2.0 no signal
122 Appendix Disorder 3 2.0 2.0 no signal
123 Gastroenteritis Viral 38 2.0 2.0 no signal
124 Hypervolaemia 10 2.0 2.0 no signal
125 Sluggishness 21 1.9 1.9 no signal
126 Axillary Pain 3 1.9 1.9 no signal
127 Increased Appetite 38 1.9 1.9 no signal
128 Hospitalisation 307 1.9 1.9 no signal
129 Eye Operation 9 1.9 1.9 no signal
130 Renal Function Test Abnormal 9 1.8 1.8 no signal
131 Adverse Event 180 1.8 1.8 no signal
132 Change Of Bowel Habit 4 1.8 1.8 no signal
133 Cholecystectomy 22 1.8 1.8 no signal
134 Costochondritis 3 1.7 1.7 no signal
135 Ill-defined Disorder 110 1.7 1.7 no signal
136 Vomiting 833 1.7 1.7 no signal
137 Pain 1,085 1.7 1.7 no signal
138 Heavy Menstrual Bleeding 14 1.7 1.7 no signal
139 Blood Count Abnormal 27 1.7 1.7 no signal
140 Laziness 3 1.6 1.6 no signal
141 Exposure To Sars-cov-2 3 1.6 1.6 no signal
142 Gastrointestinal Disorder 153 1.6 1.6 no signal
143 Arthritis Infective 8 1.6 1.6 no signal
144 Serum Ferritin Increased 9 1.6 1.6 no signal
145 Food Poisoning 9 1.6 1.6 no signal
146 Appendicectomy 6 1.6 1.6 no signal
147 Pulmonary Infarction 4 1.6 1.6 no signal
148 Illness 166 1.6 1.6 no signal
149 Platelet Disorder 4 1.5 1.5 no signal
150 Systemic Inflammatory Response Syndrome 6 1.5 1.5 no signal
151 Polymenorrhoea 5 1.5 1.5 no signal
152 Faeces Hard 6 1.5 1.5 no signal
153 Covid-19 271 1.4 1.4 no signal
154 Urine Odour Abnormal 9 1.4 1.4 no signal
155 Full Blood Count Decreased 30 1.4 1.4 no signal
156 Limb Operation 7 1.4 1.4 no signal
157 Gout 26 1.4 1.4 no signal
158 Bowel Movement Irregularity 11 1.4 1.4 no signal
159 Red Blood Cell Count Increased 4 1.4 1.4 no signal
160 Ear Swelling 3 1.3 1.3 no signal
161 Blood Test Abnormal 20 1.3 1.3 no signal
162 Vascular Occlusion 3 1.3 1.3 no signal
163 Hepatic Pain 6 1.3 1.3 no signal
164 Adenovirus Infection 4 1.3 1.3 no signal
165 Vein Disorder 7 1.3 1.3 no signal
166 Swelling Face 90 1.3 1.3 no signal
167 Appetite Disorder 9 1.3 1.3 no signal
168 Atypical Pneumonia 4 1.3 1.3 no signal
169 Lip Dry 12 1.3 1.3 no signal
170 Pneumonia 431 1.3 1.3 no signal
171 Rash 574 1.2 1.3 no signal
172 Haematocrit Increased 3 1.2 1.2 no signal
173 Migraine 124 1.2 1.2 no signal
174 Fatigue 1,007 1.2 1.2 no signal
175 Haematological Infection 3 1.2 1.2 no signal
176 Flatulence 73 1.2 1.2 no signal
177 Periorbital Swelling 7 1.2 1.2 no signal
178 Ulcer 20 1.2 1.2 no signal
179 Weight Abnormal 3 1.2 1.2 no signal
180 Near Death Experience 4 1.2 1.2 no signal
181 Blood Bilirubin Increased 33 1.1 1.1 no signal
182 Malaise 535 1.1 1.1 no signal
183 Stem Cell Transplant 3 1.1 1.1 no signal
184 Chest Pain 224 1.1 1.1 no signal
185 Seasonal Allergy 17 1.1 1.1 no signal
186 Penis Disorder 3 1.1 1.1 no signal
187 Pharyngitis Streptococcal 13 1.1 1.1 no signal
188 Hypoaesthesia Oral 18 1.1 1.1 no signal
189 Plantar Fasciitis 4 1.1 1.1 no signal
190 Blood Iron Decreased 14 1.1 1.1 no signal
191 Vitamin D Decreased 10 1.1 1.1 no signal
192 Musculoskeletal Chest Pain 18 1.1 1.1 no signal
193 Respiratory Syncytial Virus Infection 10 1.1 1.1 no signal
194 Product Distribution Issue 10 1.1 1.1 no signal
195 Product Dispensing Issue 4 1.1 1.1 no signal
196 Nonspecific Reaction 6 1.0 1.0 no signal
197 Vascular Device Infection 5 1.0 1.0 no signal
198 Retinopathy 4 1.0 1.0 no signal
199 Chromaturia 24 1.0 1.0 no signal
200 Neutrophil Count Abnormal 3 1.0 1.0 no signal
201 Pyrexia 367 1.0 1.0 no signal
202 Renal Disorder 49 1.0 1.0 no signal
203 Pulmonary Pain 3 1.0 1.0 no signal
204 Jaundice 28 1.0 1.0 no signal
205 Kidney Transplant Rejection 5 1.0 1.0 no signal
206 Rehabilitation Therapy 4 1.0 1.0 no signal
207 Retching 22 1.0 1.0 no signal
208 Thrombosis 82 1.0 1.0 no signal
209 Defaecation Urgency 7 0.9 0.9 no signal
210 Bone Marrow Disorder 3 0.9 0.9 no signal
211 Dyschezia 3 0.9 0.9 no signal
212 Creatinine Renal Clearance Decreased 4 0.9 0.9 no signal
213 Menstrual Disorder 8 0.9 0.9 no signal
214 Peripheral Swelling 149 0.9 0.9 no signal
215 Tonsillitis 5 0.9 0.9 no signal
216 Constipation 207 0.9 0.9 no signal
217 Uterine Leiomyoma 7 0.9 0.9 no signal
218 Haematocrit Decreased 19 0.9 0.9 no signal
219 Hallucinations, Mixed 4 0.9 0.9 no signal
220 Splenomegaly 11 0.9 0.9 no signal
221 Gait Inability 31 0.9 0.9 no signal
222 Poor Peripheral Circulation 4 0.9 0.9 no signal
223 Vitamin D Deficiency 9 0.9 0.9 no signal
224 Intentional Product Use Issue 80 0.9 0.9 no signal
225 Recalled Product Administered 8 0.9 0.9 no signal
226 Tongue Discolouration 4 0.9 0.9 no signal
227 Dehydration 121 0.9 0.9 no signal
228 Weight Decreased 251 0.8 0.8 no signal
229 Thirst 16 0.8 0.8 no signal
230 Oropharyngeal Discomfort 8 0.8 0.8 no signal
231 Pain In Extremity 264 0.8 0.8 no signal
232 Hepatic Enzyme Increased 60 0.8 0.8 no signal
233 Respiration Abnormal 6 0.8 0.8 no signal
234 Blood Lactate Dehydrogenase Increased 14 0.8 0.8 no signal
235 Abdominal Distension 90 0.8 0.8 no signal
236 Functional Gastrointestinal Disorder 3 0.8 0.8 no signal
237 Decreased Appetite 200 0.8 0.8 no signal
238 Renal Impairment 72 0.8 0.8 no signal
239 Hypersensitivity 159 0.8 0.8 no signal
240 Product Preparation Issue 5 0.8 0.8 no signal
241 Influenza 95 0.8 0.8 no signal
242 Fibrin D Dimer Increased 3 0.8 0.8 no signal
243 Hypersomnia 24 0.8 0.8 no signal
244 Paraesthesia Oral 12 0.8 0.8 no signal
245 Eye Haemorrhage 11 0.8 0.8 no signal
246 Gastrointestinal Pain 9 0.8 0.8 no signal
247 Skin Hyperpigmentation 7 0.8 0.8 no signal
248 Pigmentation Disorder 5 0.8 0.8 no signal
249 Bone Pain 47 0.8 0.8 no signal
250 Blood Potassium Increased 13 0.8 0.8 no signal
251 Back Pain 186 0.8 0.8 no signal
252 Aneurysm 4 0.8 0.8 no signal
253 Loss Of Control Of Legs 3 0.7 0.7 no signal
254 Oral Infection 3 0.7 0.7 no signal
255 Nodule 10 0.7 0.7 no signal
256 Aplastic Anaemia 4 0.7 0.7 no signal
257 Somnolence 153 0.7 0.7 no signal
258 Skin Mass 5 0.7 0.7 no signal
259 Eating Disorder 16 0.7 0.7 no signal
260 Vitamin B12 Deficiency 3 0.7 0.7 no signal
261 Laboratory Test Abnormal 22 0.7 0.7 no signal
262 Enuresis 3 0.7 0.7 no signal
263 Surgery 43 0.7 0.7 no signal
264 Pregnancy 15 0.7 0.7 no signal
265 Hypoxia 26 0.7 0.7 no signal
266 Organ Failure 3 0.7 0.7 no signal
267 Product Physical Consistency Issue 4 0.7 0.7 no signal
268 Goitre 3 0.7 0.7 no signal
269 Dizziness 362 0.7 0.7 no signal
270 Exposure During Pregnancy 45 0.7 0.7 no signal
271 Eosinophil Count Increased 6 0.7 0.7 no signal
272 Thyroid Function Test Abnormal 3 0.7 0.7 no signal
273 Streptococcal Infection 4 0.7 0.7 no signal
274 Urticaria 119 0.7 0.7 no signal
275 Pruritus 264 0.7 0.7 no signal
276 Musculoskeletal Discomfort 12 0.7 0.7 no signal
277 Epistaxis 52 0.7 0.7 no signal
278 Staphylococcal Bacteraemia 3 0.7 0.7 no signal
279 Oral Disorder 5 0.6 0.6 no signal
280 Bacteraemia 8 0.6 0.6 no signal
281 Rhinitis Allergic 3 0.6 0.6 no signal
282 Urine Abnormality 3 0.6 0.6 no signal
283 Red Blood Cell Count Decreased 19 0.6 0.6 no signal
284 Platelet Count Abnormal 4 0.6 0.6 no signal
285 Osteomyelitis 12 0.6 0.6 no signal
286 Liver Function Test Increased 14 0.6 0.6 no signal
287 Liver Disorder 29 0.6 0.6 no signal
288 Gastrooesophageal Reflux Disease 52 0.6 0.6 no signal
289 Limb Discomfort 20 0.6 0.6 no signal
290 Pulmonary Embolism 61 0.6 0.6 no signal
291 Loss Of Personal Independence In Daily Activities 30 0.6 0.6 no signal
292 Product Availability Issue 14 0.6 0.6 no signal
293 Therapeutic Response Unexpected 28 0.6 0.6 no signal
294 Presyncope 15 0.6 0.6 no signal
295 Weight Increased 138 0.6 0.6 no signal
296 Abnormal Faeces 5 0.6 0.6 no signal
297 Ligament Sprain 6 0.6 0.6 no signal
298 Protein Urine Present 3 0.6 0.6 no signal
299 Cognitive Disorder 28 0.6 0.6 no signal
300 Taste Disorder 12 0.6 0.6 no signal
301 Drug Interaction 95 0.6 0.6 no signal
302 White Blood Cell Count Increased 23 0.6 0.6 no signal
303 Road Traffic Accident 25 0.6 0.6 no signal
304 Bacterial Infection 11 0.6 0.6 no signal
305 Hypertransaminasaemia 4 0.6 0.6 no signal
306 Hyperbilirubinaemia 6 0.5 0.5 no signal
307 Intermenstrual Bleeding 3 0.5 0.5 no signal
308 Blood Magnesium Decreased 5 0.5 0.5 no signal
309 Periorbital Oedema 3 0.5 0.5 no signal
310 Glomerular Filtration Rate Decreased 7 0.5 0.5 no signal
311 Feeling Jittery 11 0.5 0.5 no signal
312 Oral Discomfort 8 0.5 0.5 no signal
313 Nasopharyngitis 106 0.5 0.5 no signal
314 Oxygen Saturation Decreased 32 0.5 0.5 no signal
315 Stress 41 0.5 0.5 no signal
316 Infection 82 0.5 0.5 no signal
317 Renal Pain 6 0.5 0.5 no signal
318 Dermatitis Allergic 7 0.5 0.5 no signal
319 Facial Pain 5 0.5 0.5 no signal
320 Lethargy 32 0.5 0.5 no signal
321 Blood Pressure Abnormal 11 0.5 0.5 no signal
322 Pulmonary Thrombosis 6 0.5 0.5 no signal
323 Intentional Underdose 4 0.5 0.5 no signal
324 Choking Sensation 3 0.5 0.5 no signal
325 Feeling Abnormal 131 0.5 0.5 no signal
326 Rash Maculo-papular 12 0.5 0.5 no signal
327 Dyspepsia 53 0.5 0.5 no signal
328 Arthralgia 222 0.5 0.5 no signal
329 Dysmenorrhoea 7 0.5 0.5 no signal
330 Asthenia 199 0.5 0.5 no signal
331 Knee Arthroplasty 11 0.5 0.5 no signal
332 Swelling 49 0.5 0.5 no signal
333 Lower Limb Fracture 10 0.5 0.5 no signal
334 Supraventricular Tachycardia 5 0.5 0.5 no signal
335 Product Taste Abnormal 7 0.5 0.5 no signal
336 Muscle Spasms 95 0.5 0.5 no signal
337 Skin Warm 3 0.5 0.5 no signal
338 Mood Altered 14 0.5 0.5 no signal
339 Pulmonary Oedema 23 0.5 0.5 no signal
340 Furuncle 4 0.5 0.5 no signal
341 Pleurisy 3 0.5 0.5 no signal
342 Aphonia 7 0.5 0.5 no signal
343 Multiple Organ Dysfunction Syndrome 14 0.5 0.5 no signal
344 Sinus Headache 3 0.5 0.5 no signal
345 Toxic Skin Eruption 5 0.5 0.5 no signal
346 Condition Aggravated 145 0.5 0.4 no signal
347 Weight Fluctuation 5 0.5 0.5 no signal
348 Skin Discolouration 22 0.4 0.4 no signal
349 Proteinuria 9 0.4 0.4 no signal
350 Vertigo 29 0.4 0.4 no signal
351 Incontinence 5 0.4 0.4 no signal
352 Cardiac Operation 4 0.4 0.4 no signal
353 White Blood Cell Count Abnormal 3 0.4 0.4 no signal
354 Mental Status Changes 13 0.4 0.4 no signal
355 Joint Injury 10 0.4 0.4 no signal
356 Night Sweats 15 0.4 0.4 no signal
357 Cerebrovascular Accident 79 0.4 0.4 no signal
358 Galactorrhoea 3 0.4 0.4 no signal
359 Respiratory Tract Infection 12 0.4 0.4 no signal
360 Faeces Discoloured 10 0.4 0.4 no signal
361 Localised Infection 11 0.4 0.4 no signal
362 Fluid Retention 23 0.4 0.4 no signal
363 Adverse Reaction 6 0.4 0.4 no signal
364 Skin Infection 5 0.4 0.4 no signal
365 Hunger 6 0.4 0.4 no signal
366 Rash Papular 10 0.4 0.4 no signal
367 Scab 5 0.4 0.4 no signal
368 Gingival Bleeding 6 0.4 0.4 no signal
369 Retinal Detachment 4 0.4 0.4 no signal
370 Dyspnoea 244 0.4 0.4 no signal
371 Appendicitis 4 0.4 0.4 no signal
372 Flank Pain 4 0.4 0.4 no signal
373 Product Supply Issue 3 0.4 0.4 no signal
374 Retinal Haemorrhage 3 0.4 0.4 no signal
375 Cholecystitis 5 0.4 0.4 no signal
376 Gastric Ulcer 8 0.4 0.4 no signal
377 Accident 5 0.4 0.4 no signal
378 Amenorrhoea 7 0.4 0.4 no signal
379 Palpitations 49 0.4 0.4 no signal
380 Pharyngeal Swelling 4 0.4 0.4 no signal
381 Therapy Change 4 0.4 0.4 no signal
382 Atelectasis 4 0.4 0.4 no signal
383 Haemorrhoids 8 0.4 0.4 no signal
384 Arthropod Bite 3 0.4 0.4 no signal
385 Cerebral Disorder 3 0.4 0.4 no signal
386 Eye Swelling 15 0.4 0.4 no signal
387 Pharyngitis 5 0.4 0.4 no signal
388 Salivary Hypersecretion 4 0.4 0.4 no signal
389 Joint Swelling 48 0.4 0.4 no signal
390 Blindness 16 0.4 0.4 no signal
391 Lip Swelling 13 0.4 0.4 no signal
392 Feeling Hot 24 0.4 0.4 no signal
393 Gallbladder Disorder 7 0.4 0.4 no signal
394 Muscle Twitching 9 0.4 0.4 no signal
395 Oropharyngeal Pain 36 0.4 0.4 no signal
396 Lung Disorder 19 0.4 0.4 no signal
397 Leukocytosis 7 0.4 0.4 no signal
398 Product Preparation Error 8 0.4 0.4 no signal
399 Pelvic Fracture 3 0.4 0.4 no signal
400 Death 331 0.4 0.4 no signal
401 Panic Attack 14 0.4 0.4 no signal
402 Tooth Infection 5 0.4 0.4 no signal
403 Respiratory Tract Congestion 6 0.4 0.4 no signal
404 Menstruation Irregular 10 0.4 0.4 no signal
405 Ear Infection 10 0.4 0.4 no signal
406 Blood Disorder 3 0.4 0.4 no signal
407 Drug Intolerance 36 0.4 0.4 no signal
408 Poor Quality Sleep 8 0.4 0.4 no signal
409 Rash Macular 13 0.4 0.4 no signal
410 Dysphagia 35 0.3 0.3 no signal
411 Limb Injury 10 0.3 0.3 no signal
412 Ocular Discomfort 4 0.3 0.3 no signal
413 Hiccups 3 0.3 0.3 no signal
414 Sleep Apnoea Syndrome 7 0.3 0.3 no signal
415 Blood Potassium Decreased 11 0.3 0.3 no signal
416 Peripheral Coldness 5 0.3 0.3 no signal
417 Feeling Cold 10 0.3 0.3 no signal
418 Glossodynia 8 0.3 0.3 no signal
419 Blindness Unilateral 5 0.3 0.3 no signal
420 Pseudomonas Infection 3 0.3 0.3 no signal
421 Sinus Disorder 7 0.3 0.3 no signal
422 Drug Reaction With Eosinophilia And Systemic Symptoms 9 0.3 0.3 no signal
423 Impaired Driving Ability 4 0.3 0.3 no signal
424 Scar 6 0.3 0.3 no signal
425 Internal Haemorrhage 4 0.3 0.3 no signal
426 Upper Respiratory Tract Infection 16 0.3 0.3 no signal
427 Nail Disorder 3 0.3 0.3 no signal
428 Gastric Disorder 12 0.3 0.3 no signal
429 Chest Discomfort 35 0.3 0.3 no signal
430 Brain Fog 5 0.3 0.3 no signal
431 Gastritis 9 0.3 0.3 no signal
432 Head Discomfort 6 0.3 0.3 no signal
433 Fluid Overload 5 0.3 0.3 no signal
434 Anal Incontinence 3 0.3 0.3 no signal
435 Gastrointestinal Infection 3 0.3 0.3 no signal
436 Wrist Fracture 4 0.3 0.3 no signal
437 Hot Flush 25 0.3 0.3 no signal
438 Seizure 38 0.3 0.3 no signal
439 Neuralgia 8 0.3 0.3 no signal
440 Hepatic Cytolysis 4 0.3 0.3 no signal
441 Bone Disorder 6 0.3 0.3 no signal
442 Alopecia 64 0.3 0.3 no signal
443 Generalised Oedema 4 0.3 0.3 no signal
444 Transient Ischaemic Attack 11 0.3 0.3 no signal
445 Adverse Drug Reaction 29 0.3 0.3 no signal
446 Chills 38 0.3 0.3 no signal
447 Cyst 4 0.3 0.3 no signal
448 Tooth Extraction 4 0.3 0.3 no signal
449 Product Complaint 8 0.3 0.3 no signal
450 Rash Erythematous 15 0.3 0.3 no signal
451 Ageusia 8 0.3 0.3 no signal
452 Pain In Jaw 9 0.3 0.3 no signal
453 Abdominal Pain Lower 8 0.3 0.3 no signal
454 Anaemia 60 0.3 0.3 no signal
455 Discomfort 19 0.3 0.3 no signal
456 Acute Respiratory Failure 6 0.3 0.3 no signal
457 Skin Exfoliation 26 0.3 0.3 no signal
458 Insomnia 83 0.3 0.3 no signal
459 Lymphadenopathy 11 0.3 0.3 no signal
460 Oral Candidiasis 4 0.3 0.3 no signal
461 Urinary Tract Infection 52 0.3 0.3 no signal
462 Bedridden 4 0.3 0.3 no signal
463 Hepatomegaly 3 0.3 0.3 no signal
464 Staphylococcal Infection 10 0.3 0.3 no signal
465 Product Administration Error 6 0.3 0.3 no signal
466 Ovarian Cyst 3 0.3 0.3 no signal
467 Eczema 15 0.3 0.3 no signal
468 Dry Mouth 24 0.3 0.3 no signal
469 Sepsis 33 0.3 0.3 no signal
470 Acute Hepatic Failure 4 0.3 0.3 no signal
471 Subarachnoid Haemorrhage 3 0.3 0.3 no signal
472 Tooth Abscess 3 0.3 0.3 no signal
473 Deep Vein Thrombosis 19 0.3 0.3 no signal
474 Menstruation Delayed 3 0.3 0.3 no signal
475 Depressed Mood 15 0.3 0.3 no signal
476 Clostridium Difficile Colitis 3 0.3 0.3 no signal
477 Dry Skin 37 0.3 0.3 no signal
478 Ischaemic Stroke 5 0.3 0.3 no signal
479 Wound Infection 3 0.3 0.3 no signal
480 Hypokinesia 4 0.3 0.3 no signal
481 Pulmonary Arterial Hypertension 4 0.3 0.3 no signal
482 Gastroenteritis 4 0.3 0.3 no signal
483 Sinusitis 28 0.3 0.3 no signal
484 Conjunctivitis 5 0.3 0.3 no signal
485 Dental Caries 3 0.3 0.3 no signal
486 Therapeutic Product Effect Decreased 12 0.3 0.3 no signal
487 Malnutrition 3 0.3 0.3 no signal
488 Diplopia 7 0.3 0.3 no signal
489 Neck Pain 15 0.3 0.3 no signal
490 Hepatic Cirrhosis 5 0.3 0.3 no signal
491 Blood Calcium Decreased 3 0.2 0.2 no signal
492 Aspartate Aminotransferase Increased 14 0.2 0.2 no signal
493 Heart Rate Increased 26 0.2 0.2 no signal
494 Device Related Infection 4 0.2 0.2 no signal
495 Ankle Fracture 4 0.2 0.2 no signal
496 Choking 5 0.2 0.2 no signal
497 Sleep Disorder 18 0.2 0.2 no signal
498 Kidney Infection 5 0.2 0.2 no signal
499 Haematochezia 14 0.2 0.2 no signal
500 Wrong Technique In Product Usage Process 51 0.2 0.2 no signal
501 Wound 7 0.2 0.2 no signal
502 Mood Swings 8 0.2 0.2 no signal
503 Cough 70 0.2 0.2 no signal
504 Irritability 15 0.2 0.2 no signal
505 Rhinorrhoea 16 0.2 0.2 no signal
506 Drug Hypersensitivity 48 0.2 0.2 no signal
507 Body Temperature Increased 5 0.2 0.2 no signal
508 Alanine Aminotransferase Increased 15 0.2 0.2 no signal
509 Cardiomegaly 3 0.2 0.2 no signal
510 Skin Disorder 8 0.2 0.2 no signal
511 Pollakiuria 10 0.2 0.2 no signal
512 Incorrect Route Of Product Administration 4 0.2 0.2 no signal
513 Hypoaesthesia 35 0.2 0.2 no signal
514 Hypoacusis 10 0.2 0.2 no signal
515 Asthma 26 0.2 0.2 no signal
516 Hepatic Failure 7 0.2 0.2 no signal
517 Product Dispensing Error 5 0.2 0.2 no signal
518 Mental Disorder 10 0.2 0.2 no signal
519 Hyperkalaemia 8 0.2 0.2 no signal
520 Eosinophilia 4 0.2 0.2 no signal
521 Joint Stiffness 6 0.2 0.2 no signal
522 Burning Sensation 16 0.2 0.2 no signal
523 Anxiety 65 0.2 0.2 no signal
524 Dysgeusia 17 0.2 0.2 no signal
525 Hyperhidrosis 29 0.2 0.2 no signal
526 Joint Range Of Motion Decreased 3 0.2 0.2 no signal
527 Cardiac Disorder 21 0.2 0.2 no signal
528 Oral Pain 5 0.2 0.2 no signal
529 Hair Texture Abnormal 3 0.2 0.2 no signal
530 Nasal Congestion 13 0.2 0.2 no signal
531 Toothache 4 0.2 0.2 no signal
532 Skin Lesion 6 0.2 0.2 no signal
533 Heart Rate Irregular 5 0.2 0.2 no signal
534 Pallor 6 0.2 0.2 no signal
535 Crying 8 0.2 0.2 no signal
536 Depression 50 0.2 0.2 no signal
537 Memory Impairment 30 0.2 0.2 no signal
538 Cellulitis 11 0.2 0.2 no signal
539 Pericardial Effusion 5 0.2 0.2 no signal
540 Photophobia 4 0.2 0.2 no signal
541 Ocular Hyperaemia 10 0.2 0.2 no signal
542 Skin Reaction 3 0.2 0.2 no signal
543 Foot Fracture 4 0.2 0.2 no signal
544 Eructation 4 0.2 0.2 no signal
545 Blood Urine Present 4 0.2 0.2 no signal
546 Cholestasis 4 0.2 0.2 no signal
547 Product Use Issue 39 0.2 0.2 no signal
548 Pancreatitis 11 0.2 0.2 no signal
549 Platelet Count Decreased 22 0.2 0.2 no signal
550 Apathy 3 0.2 0.2 no signal
551 Ear Pain 4 0.2 0.2 no signal
552 Cardiac Arrest 17 0.2 0.2 no signal
553 Ascites 6 0.2 0.2 no signal
554 Renal Failure 27 0.2 0.2 no signal
555 Blood Alkaline Phosphatase Increased 5 0.2 0.2 no signal
556 Product Physical Issue 4 0.2 0.2 no signal
557 Systemic Lupus Erythematosus 7 0.2 0.2 no signal
558 Product Prescribing Issue 4 0.2 0.2 no signal
559 Blood Pressure Increased 30 0.2 0.2 no signal
560 Tinnitus 9 0.2 0.2 no signal
561 Rib Fracture 4 0.2 0.2 no signal
562 Erectile Dysfunction 5 0.2 0.2 no signal
563 Emotional Disorder 6 0.2 0.2 no signal
564 Haematoma 5 0.2 0.2 no signal
565 Nervousness 10 0.2 0.2 no signal
566 Paraesthesia 30 0.2 0.2 no signal
567 Head Injury 6 0.2 0.2 no signal
568 Pneumothorax 3 0.2 0.2 no signal
569 Hallucination, Auditory 3 0.2 0.2 no signal
570 Abscess 3 0.2 0.2 no signal
571 Contusion 18 0.2 0.2 no signal
572 Loss Of Consciousness 24 0.2 0.2 no signal
573 Pain Of Skin 5 0.2 0.2 no signal
574 Eye Disorder 6 0.2 0.2 no signal
575 Chronic Kidney Disease 14 0.2 0.2 no signal
576 Angioedema 8 0.2 0.2 no signal
577 Inappropriate Schedule Of Product Administration 32 0.2 0.2 no signal
578 Pleural Effusion 11 0.2 0.2 no signal
579 Sneezing 4 0.2 0.2 no signal
580 Arthritis 14 0.2 0.2 no signal
581 Anger 6 0.2 0.2 no signal
582 Abnormal Behaviour 7 0.2 0.2 no signal
583 Cardiac Failure Congestive 14 0.2 0.2 no signal
584 Dysphonia 10 0.2 0.2 no signal
585 Musculoskeletal Stiffness 15 0.2 0.2 no signal
586 Musculoskeletal Pain 9 0.2 0.2 no signal
587 Cold Sweat 3 0.2 0.2 no signal
588 Product Prescribing Error 4 0.2 0.2 no signal
589 Vision Blurred 23 0.2 0.2 no signal
590 Coma 8 0.2 0.2 no signal
591 Oedema 9 0.2 0.2 no signal
592 White Blood Cell Count Decreased 18 0.2 0.2 no signal
593 Liver Injury 4 0.2 0.2 no signal
594 Atrial Fibrillation 16 0.2 0.2 no signal
595 End Stage Renal Disease 3 0.2 0.2 no signal
596 Swollen Tongue 5 0.2 0.2 no signal
597 Nervous System Disorder 5 0.2 0.1 no signal
598 Throat Irritation 7 0.1 0.1 no signal
599 Fall 52 0.1 0.1 no signal
600 Blood Creatinine Increased 10 0.1 0.1 no signal
601 Eye Pruritus 5 0.1 0.1 no signal
602 Acute Kidney Injury 23 0.1 0.1 no signal
603 Urinary Retention 5 0.1 0.1 no signal
604 Fungal Infection 5 0.1 0.1 no signal
605 Dyskinesia 6 0.1 0.1 no signal
606 Disturbance In Attention 8 0.1 0.1 no signal
607 Myalgia 25 0.1 0.1 no signal
608 Disease Recurrence 7 0.1 0.1 no signal
609 Respiratory Arrest 4 0.1 0.1 no signal
610 Diabetes Mellitus 11 0.1 0.1 no signal
611 Visual Impairment 17 0.1 0.1 no signal
612 Cardiac Failure 11 0.1 0.1 no signal
613 Liver Function Test Abnormal 4 0.1 0.1 no signal
614 Restlessness 5 0.1 0.1 no signal
615 Inflammation 7 0.1 0.1 no signal
616 Hepatic Function Abnormal 5 0.1 0.1 no signal
617 Bronchitis 10 0.1 0.1 no signal
618 Lacrimation Increased 4 0.1 0.1 no signal
619 Renal Injury 4 0.1 0.1 no signal
620 Tremor 22 0.1 0.1 no signal
621 Unevaluable Event 10 0.1 0.1 no signal
622 Muscular Weakness 15 0.1 0.1 no signal
623 Skin Irritation 6 0.1 0.1 no signal
624 Balance Disorder 11 0.1 0.1 no signal
625 Eye Pain 7 0.1 0.1 no signal
626 Eye Irritation 7 0.1 0.1 no signal
627 Arthropathy 7 0.1 0.1 no signal
628 Gait Disturbance 24 0.1 0.1 no signal
629 Blister 7 0.1 0.1 no signal
630 Drug Ineffective 164 0.1 0.1 no signal
631 Mental Impairment 3 0.1 0.1 no signal
632 Respiratory Failure 9 0.1 0.1 no signal
633 Amnesia 8 0.1 0.1 no signal
634 Impaired Healing 4 0.1 0.1 no signal
635 Influenza Like Illness 10 0.1 0.1 no signal
636 Blood Pressure Decreased 8 0.1 0.1 no signal
637 Expired Product Administered 4 0.1 0.1 no signal
638 Syncope 12 0.1 0.1 no signal
639 Wheezing 7 0.1 0.1 no signal
640 Acne 9 0.1 0.1 no signal
641 Haematemesis 3 0.1 0.1 no signal
642 Hypertension 25 0.1 0.1 no signal
643 Anaphylactic Shock 3 0.1 0.1 no signal
644 Unresponsive To Stimuli 3 0.1 0.1 no signal
645 Stomatitis 7 0.1 0.1 no signal
646 Nightmare 4 0.1 0.1 no signal
647 Heart Rate Decreased 4 0.1 0.1 no signal
648 Cerebral Haemorrhage 4 0.1 0.1 no signal
649 Underdose 8 0.1 0.1 no signal
650 Dysuria 4 0.1 0.1 no signal
651 Medication Error 6 0.1 0.1 no signal
652 Thrombocytopenia 12 0.1 0.1 no signal
653 Dyspnoea Exertional 4 0.1 0.1 no signal
654 Confusional State 17 0.1 0.1 no signal
655 Angina Pectoris 3 0.1 0.1 no signal
656 Therapeutic Response Decreased 6 0.1 0.1 no signal
657 Aphasia 3 0.1 0.1 no signal
658 Skin Burning Sensation 7 0.1 0.1 no signal
659 Oedema Peripheral 12 0.1 0.1 no signal
660 Femur Fracture 3 0.1 0.1 no signal
661 Withdrawal Syndrome 4 0.1 0.1 no signal
662 Osteoarthritis 4 0.1 0.1 no signal
663 Cystitis 3 0.1 0.1 no signal
664 Hip Fracture 3 0.1 0.1 no signal
665 Movement Disorder 3 0.1 0.1 no signal
666 Anaphylactic Reaction 5 0.1 0.1 no signal
667 Tachycardia 8 0.1 0.1 no signal
668 Pancytopenia 5 0.1 0.1 no signal
669 Visual Acuity Reduced 3 0.1 0.1 no signal
670 Nephrolithiasis 4 0.1 0.1 no signal
671 Herpes Zoster 5 0.1 0.1 no signal
672 Delirium 3 0.1 0.1 no signal
673 Myocardial Infarction 15 0.1 0.1 no signal
674 Arrhythmia 4 0.1 0.1 no signal
675 Mobility Decreased 6 0.1 0.1 no signal
676 Agitation 6 0.1 0.1 no signal
677 Hallucination 6 0.1 0.1 no signal
678 Colitis 3 0.1 0.1 no signal
679 Haemorrhage 8 0.1 0.1 no signal
680 Suicidal Ideation 7 0.1 0.1 no signal
681 Extra Dose Administered 3 0.1 0.1 no signal
682 Hypotension 15 0.1 0.1 no signal
683 Neutrophil Count Decreased 3 0.1 0.1 no signal
684 Foetal Exposure During Pregnancy 6 0.1 0.1 no signal
685 Osteoporosis 3 0.1 0.1 no signal
686 Gastrointestinal Haemorrhage 6 0.1 0.1 no signal
687 Septic Shock 3 0.1 0.1 no signal
688 Maternal Exposure During Pregnancy 6 0.1 0.1 no signal
689 Disease Progression 8 0.1 0.1 no signal
690 Emotional Distress 8 0.1 0.1 no signal
691 Productive Cough 3 0.1 0.1 no signal
692 Incorrect Dose Administered 14 0.1 0.1 no signal
693 Neoplasm Malignant 4 0.1 0.1 no signal
694 Flushing 6 0.1 0.1 no signal
695 Speech Disorder 3 0.1 0.1 no signal
696 Injury 4 0.1 0.1 no signal
697 Therapeutic Product Effect Incomplete 4 0.1 0.1 no signal
698 Bradycardia 3 0.1 0.1 no signal
699 Hyponatraemia 3 0.1 0.1 no signal
700 Cataract 3 0.0 0.0 no signal
701 Erythema 10 0.0 0.0 no signal
702 Rheumatoid Arthritis 4 0.0 0.0 no signal
703 General Physical Health Deterioration 4 0.0 0.0 no signal
704 Neuropathy Peripheral 3 0.0 0.0 no signal
705 Neutropenia 4 0.0 0.0 no signal
706 No Adverse Event 4 0.0 0.0 no signal
707 Blood Glucose Increased 4 0.0 0.0 no signal
708 Product Use In Unapproved Indication 5 0.0 0.0 no signal