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Which drugs are most reported with Faeces soft?

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 7,142 reports · 324 co-occurring drugs

As of the last recalculation, Faeces Soft appears in 7,142 FAERS reports alongside 324 co-occurring drug terms. The strongest observed disproportionality signal is VEDOLIZUMAB (PRR 35.4).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Vedolizumab	916	35.4	35.8
Nintedanib	311	30.2	30.5
Selexipag	171	19.7	19.9
Instalax Polyethylene Glycol 3350	75	17.8	17.9
Polyethylene Glycol 400	75	17.4	17.5
Lanreotide Acetate	45	16.8	16.9
Mesalamine	292	15.8	15.8
Octreotide Acetate	138	13.4	13.4
Infliximab-Dyyb	127	12.9	12.9
Psyllium Husk	40	11.9	11.9
Polyethylene Glycol 3350	358	11.4	11.5
Ado-Trastuzumab Emtansine	29	10.1	10.1
Cholestyramine	41	9.9	10.0
Abemaciclib	58	8.5	8.5
Loperamide Hydrochloride And Dimethicone	86	7.9	7.9
Loperamide Hydrochloride	115	7.6	7.6
Voxelotor	58	7.6	7.6
Pantoprazole Sodium In 0.9% Sodium Chloride	156	7.5	7.5
Pantoprazole Sodium Injection	156	7.5	7.5
Teduglutide	34	7.4	7.4
Dexlansoprazole	104	7.4	7.4
Telmisartan	41	6.7	6.7
Diroximel Fumarate	27	6.6	6.6
Apremilast	312	6.5	6.5
Iron	143	6.3	6.4
Dimenhydrinate	22	6.0	6.0
Riociguat	66	5.9	6.0
Tadalafil	195	5.8	5.8
Loperamide Hydrochloride Oral	20	5.7	5.7
Alpelisib	17	5.7	5.7
Desoximetasone	36	5.5	5.5
Loperamide Hcl	24	5.5	5.5
Teriflunomide	80	5.2	5.2
Relugolix	41	5.1	5.1
Calcium	251	5.1	5.1
Rabeprazole	38	5.0	5.0
Colchicine	45	5.0	5.0
Heparin Sodium	23	4.9	4.9
Hydrocortisone	143	4.7	4.7
Cabozantinib	75	4.6	4.6
0Xygen	75	4.5	4.5
Oxygen	75	4.5	4.5
Treprostinil	183	4.3	4.3
Tolvaptan	21	4.2	4.2
Azathioprine	125	4.2	4.2
Macitentan	98	4.2	4.2
Dicyclomine Hydrochloride	20	4.1	4.1
Pantoprazole	343	4.1	4.1
Ciprofloxacin Hydrochloride And Hydrocortisone	29	4.1	4.1
Ursosiol	27	4.1	4.1
Selinexor	12	4.0	4.0
Regorafenib	16	4.0	4.0
Human Immunoglobulin G	28	4.0	4.0
Dutasteride	11	3.9	4.0
Goserelin	18	3.9	3.9
Zinc	33	3.9	3.9
Magnesium	109	3.9	3.9
Vitamin C	121	3.9	3.9
Zinc Chloride	33	3.9	3.9
Valganciclovir	25	3.9	3.9
Valganciclovir Hydrochloride	25	3.9	3.9
Methylprednisolone Sodium Succinate	61	3.9	3.9
Fosaprepitant Dimeglumine	18	3.8	3.8
Epoprostenol	17	3.8	3.8
Icosapent Ethyl	11	3.8	3.8
Indapamide	23	3.7	3.8
Linaclotide	34	3.7	3.7
Bosentan	64	3.7	3.7
Pancrelipase	49	3.7	3.7
Lubiprostone	12	3.7	3.7
Zinc Gluconate	33	3.7	3.7
Oxybutynin Chloride	11	3.7	3.7
Aprepitant	23	3.6	3.6
Vibegron	10	3.6	3.6
Rucaparib	11	3.6	3.6
Ursodiol	27	3.6	3.6
Prednisone	585	3.6	3.6
Axitinib	24	3.6	3.6
Budesonide	72	3.6	3.6
Ergocalciferol	452	3.6	3.6
Bosutinib	11	3.6	3.6
Candesartan	43	3.5	3.5
Pantoprazole Sodium	173	3.5	3.5
Febuxostat Tablets 40 Mg	12	3.4	3.4
Febuxostat Tablets 80 Mg	12	3.4	3.4
Rosuvastatin Calcium	33	3.4	3.4
Diphenoxylate Hydrochloride And Atropine Sulfate	16	3.4	3.4
Valsartan Oral	63	3.4	3.4
Adalimumab-Adaz	61	3.4	3.4
Risankizumab-Rzaa	92	3.3	3.3
Infliximab	242	3.3	3.3
Thiamine Hydrochloride, Riboflavin 5 Phosphate Sodium, Dexpanthenol And Niacinamide	34	3.3	3.3
Standardized Senna Concentrate	14	3.2	3.2
Cannabidiol	26	3.2	3.2
Pertuzumab	30	3.2	3.2
Ixazomib	31	3.1	3.2
Tamsulosin Hydrochloride	22	3.1	3.2
Orlistat	27	3.0	3.0
Tramadol Hydrochloride	39	3.0	3.0
Lenvatinib	34	3.0	3.0
Bisoprolol Fumarate	136	3.0	3.0
Pirfenidone	41	2.9	2.9
Azelastine	18	2.9	2.9
Letrozole Tablets	48	2.9	2.9
Ciprofloxacin Hydrochloride	96	2.9	2.9
Docusate Sodium - Sennosides	32	2.9	2.9
Niraparib	22	2.9	2.9
Pramipexole	15	2.9	2.9
Pitavastatin Calcium	10	2.9	2.9
Sildenafil	56	2.8	2.8
Biotin	30	2.8	2.8
Human Insulin	12	2.8	2.8
Metronidazole	61	2.8	2.8
Hydrocortisone Sodium Succinate	9	2.8	2.8
Triamcinolone Acetonide Ointment Usp, 0.05%	22	2.7	2.7
Hydrocortisone Acetate	68	2.7	2.7
Ambrisentan	116	2.7	2.7
Fenofibrate	33	2.7	2.7
Pazopanib Hydrochloride	25	2.7	2.7
Liothyronine Sodium	8	2.7	2.7
Nystatin Ointment	24	2.7	2.7
Nystatin Cream	24	2.7	2.7
Anti-Itch	61	2.7	2.7
Anti-Pruritic	61	2.7	2.7
Antipruritic (Anti-Itch)	61	2.7	2.7
Cool Relief Gel With Aloe	61	2.7	2.7
Drs. Hydrocortisone	61	2.7	2.7
Hydrocortisone Continuous Spray	61	2.7	2.7
Hydrocortisone Spray	61	2.7	2.7
Anti-Itch Cream	61	2.7	2.7
Hydrocortisone Lotion	61	2.7	2.7
Hydrocortisone Cream 1%	61	2.7	2.7
Hydrocortisone Cream 1/2%	61	2.7	2.7
Hydrocortisone 1%	61	2.7	2.7
Letrozole	56	2.7	2.7
Hydrocortisone Cream	61	2.7	2.7
Benzonatate	15	2.6	2.6
Amlodipine Besylate And Valsartan	10	2.6	2.6
Oral Semaglutide	66	2.6	2.6
Metoprolol Succinate Er Tablets	56	2.6	2.6
Methimazole	7	2.6	2.6
Cyanocobalamin	29	2.6	2.6
Nystatin	24	2.6	2.6
Cetirizine Hcl	8	2.5	2.5
Atovaquone	7	2.5	2.5
Sunitinib Malate	34	2.5	2.5
Fexofenadine Hcl	8	2.5	2.5
Alendronate Sodium Tablet	16	2.5	2.5
Amlodipine	227	2.5	2.5
Palbociclib	81	2.5	2.5
Irbesartan	38	2.5	2.5
Hydroxyurea	18	2.5	2.5
Sucralfate Oral	12	2.5	2.5
Ciprofloxacin	77	2.5	2.5
Sucralfate Oral Suspension	12	2.5	2.5
Lapatinib	13	2.4	2.4
Febuxostat	14	2.4	2.4
Folic Acid	204	2.4	2.4
Rifampin	12	2.4	2.4
Capecitabine	74	2.4	2.4
Acetaminophen, Guaifenesin, And Phenylephrine Hydrochloride	128	2.4	2.4
Fulvestrant	26	2.3	2.3
Venlafaxine	56	2.3	2.3
Valsartan	82	2.3	2.3
Amlodipine Besylate	114	2.3	2.3
Cyclobenzaprine	39	2.3	2.3
Mycophenolic Acid	25	2.3	2.3
Triamcinolone Acetonide	24	2.3	2.3
Chlorthalidone	9	2.3	2.3
Metformin Er 500 Mg	228	2.2	2.2
Metformin Er 750 Mg	228	2.2	2.2
Metoprolol Tartrate Injection	143	2.2	2.2
Rosuvastatin	154	2.2	2.2
Doxazosin	21	2.2	2.2
Butalbital, Acetaminophen, And Caffeine	8	2.2	2.2
Oxazepam	16	2.2	2.2
Metformin	260	2.2	2.2
Magnesium Oxide	31	2.2	2.2
Metformin Hydrochloride Tablets	42	2.1	2.1
Metformin Hydrochloride Extended-Release Tablets	42	2.1	2.1
Metformin Hydrochloride Tablet	42	2.1	2.1
Metformin Hydrochloride	43	2.1	2.1
Glecaprevir And Pibrentasvir	8	2.1	2.1
Nitrofurantoin	12	2.1	2.1
Mirabegron	28	2.1	2.1
Patiromer	10	2.1	2.1
Prochlorperazine	20	2.1	2.1
Doxazosin Mesylate	26	2.1	2.1
Nitrofurantoin (Monohydrate/Macrocrystals)	12	2.1	2.1
Metoprolol Succinate	62	2.1	2.1
Metoprolol	178	2.1	2.1
Naltrexone Hydrochloride And Bupropion Hydrochloride	6	2.1	2.1
Anastrozole Tablets	15	2.0	2.0
Fish Oil	63	2.0	2.0
Ferrous Sulfate	35	2.0	2.0
Valacyclovir Hydrochloride	49	2.0	2.0
Clobazam	17	2.0	2.0
Metoprolol Tartrate	188	2.0	2.0
Sildenafil Citrate	88	2.0	2.0
Famotidine	81	2.0	2.0
Niacin	8	2.0	2.0
Dimethyl Fumarate	84	2.0	2.0
Losartan	118	2.0	2.0
Abaloparatide	20	2.0	2.0
Nifedipine	32	2.0	2.0
Sildenafil Powder,	24	2.0	2.0
Timolol	8	1.9	1.9
Atorvastatin Calcium, Film Coated	46	1.9	1.9
Escitslopram	38	1.9	1.9
Nirmatrelvir And Ritonavir	35	1.9	1.9
Ondansetron Hydrochloride	79	1.9	1.9
Eculizumab	35	1.9	1.9
Diclofenac Sodium 1%	23	1.9	1.9
Diclofenac Sodium Topical	23	1.9	1.9
Diclofenac Sodium Topical Gel, 1%	23	1.9	1.9
Elexacaftor, Tezacaftor, And Ivacaftor	8	1.9	1.9
Posaconazole Delayed-Release	7	1.9	1.9
Lisinopril And Hydrochlorothiazide Tablets	5	1.9	1.9
Mercaptopurine	11	1.8	1.9
Ribociclib	20	1.8	1.8
Sertraline	74	1.8	1.8
Ibrutinib	51	1.8	1.8
Duloxetine	44	1.8	1.8
Mycophenilic Acid	13	1.8	1.8
Ondansetron	68	1.8	1.8
Ondansetron Tablets	68	1.8	1.8
Rifaximin	13	1.8	1.8
Posaconazole	10	1.8	1.8
Zonisamide	9	1.8	1.8
Pravastatin Sodium	12	1.8	1.8
Fexofenadine Hydrochloride	13	1.7	1.7
Ustekinumab	61	1.7	1.7
Pregabalin	160	1.7	1.7
Rifampicin	6	1.7	1.7
Bicalutamide	9	1.7	1.7
Guaifenesin	18	1.7	1.7
Valsartan And Hydrochlorothiazide	8	1.7	1.7
Amikacin	10	1.7	1.7
Lovastatin	15	1.7	1.7
Trastuzumab	40	1.7	1.7
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	12	1.7	1.7
Naproxen Sodium, Pseudoephedrine Hydrochloride	12	1.7	1.7
Amantadine	9	1.7	1.7
Avapritinib	7	1.7	1.7
Acalabrutinib	7	1.7	1.7
Voclosporin	5	1.7	1.7
Sitagliptin	41	1.7	1.7
Trifluridine And Tipiracil	6	1.6	1.6
Ruxolitinib	40	1.6	1.6
Umeclidinium	5	1.6	1.6
Tocilizumab	63	1.6	1.6
Vigabatrin	8	1.6	1.6
Oxybutynin	16	1.6	1.6
Prochlorperazine Maleate	5	1.6	1.6
Darunavir	8	1.5	1.5
Enzalutamide	31	1.5	1.5
Adalimumab	365	1.5	1.5
Iron Sucrose	5	1.5	1.5
Sitagliptin And Metformin Hydrochloride	11	1.5	1.5
Tafamidis	6	1.5	1.5
Venetoclax	31	1.5	1.5
Ozanimod Hydrochloride	4	1.4	1.4
Sorafenib	10	1.4	1.4
Tofacitinib	88	1.4	1.4
Granisetron	5	1.4	1.4
Dofetilide	5	1.4	1.4
Naproxen Sodium Tablet	25	1.4	1.4
Lumacaftor And Ivacaftor	4	1.4	1.4
Irinotecan Hydrochloride	6	1.4	1.4
Pemetrexed	10	1.4	1.4
Canakinumab	5	1.3	1.3
Pembrolizumab	48	1.3	1.3
Siponimod	4	1.3	1.3
Dapagliflozin	14	1.3	1.3
Dolutegravir Sodium	4	1.3	1.3
Peginterferon Alfa-2A	23	1.2	1.2
Hydromorphone Hydrochloride	39	1.2	1.2
Ledipasvir And Sofosbuvir	8	1.2	1.2
Vortioxetine	7	1.2	1.2
Oxaliplatin	29	1.1	1.1
Velpatasvir And Sofosbuvir	5	1.1	1.1
Paclitaxel (Aibumin-Bound)	32	1.1	1.1
Suvorexant	5	1.1	1.1
Nivolumab	37	1.1	1.1
Upadacitinib	31	1.1	1.1
Dabrafenib	8	1.1	1.1
Inclisiran	3	1.1	1.1
Abiraterone	5	1.1	1.1
Dalfampridine	26	1.1	1.1
Denosumab	73	1.1	1.1
Cenobamate	3	1.0	1.0
Ribavirin	23	1.0	1.0
Diclofenac Potassium, Film Coated	3	1.0	1.0
Diclofenac Potassium Tablets	3	1.0	1.0
Fremanezumab-Vfrm	4	1.0	1.0
Travoprost	3	1.0	1.0
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	14	1.0	1.0
Vismodegib	3	1.0	1.0
Olaparib	7	1.0	1.0
Canagliflozin	10	1.0	1.0
Ipilimumab	14	0.9	0.9
Alirocumab	8	0.9	0.9
Lenalidomide	134	0.9	0.9
Rimegepant Sulfate	4	0.9	0.9
Bimatoprost	9	0.9	0.9
Eltrombopag Olamine	7	0.9	0.9
Encorafenib	3	0.9	0.9
Buprenorphine	28	0.9	0.9
Umeclidinium Bromide And Vilanterol Trifenatate	5	0.9	0.9
Budesonide, Glycopyrrolate, And Formoterol Fumarate	3	0.8	0.8
Methoxy Polyethylene Glycol-Epoetin Beta	3	0.8	0.8
Leuprolide Acetate	21	0.8	0.8
Apalutamide	3	0.7	0.7
Ranitidine Hydrochloride	12	0.6	0.6
Abiraterone Acetate	9	0.6	0.6
Sacubitril And Valsartan	25	0.6	0.6
Dornase Alfa	4	0.6	0.6
Dulaglutide	17	0.6	0.6
Bimekizumab	4	0.5	0.5
Evolocumab	27	0.5	0.5
Tirzepatide	22	0.4	0.4
Valbenazine	3	0.3	0.3
Copper	4	0.3	0.3
Pimavanserin Tartrate	5	0.3	0.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.