OpenPV Signal Explorer
FAERS disproportionality dashboard
Reaction

Disease Complication reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,538 reports · 123 co-occurring drugs

As of the last recalculation, Disease Complication appears in 4,538 FAERS reports alongside 123 co-occurring drug terms. The strongest observed disproportionality signal is SODIUM CHLORIDE, SODIUM LACTATE, CALCIUM CHLORIDE, MAGNESIUM CHLORIDE AND DEXTROSE (PRR 36.3).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride And Dextrose6436.336.6
Voxelotor12726.726.8
Dornase Alfa10124.124.3
Icodextrin, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride11317.117.1
Rifaximin6614.614.7
Epoprostenol4114.514.5
Bosentan13913.013.0
Selexipag6311.311.4
Macitentan14910.210.2
Paricalcitol299.59.5
Tobramycin489.29.3
Gentamicin269.29.2
Piperacillin And Tazobactam248.68.7
Gentamicin Sulfate298.58.5
Remdesivir238.08.0
Lumacaftor And Ivacaftor147.57.5
Sildenafil Powder,547.07.0
Riociguat497.07.0
Cefuroxime176.86.9
Piperacillin Sodium And Tazobactam Sodium296.86.8
Sildenafil826.66.6
Agalsidase Beta136.56.5
Piperacillin Sodium,Tazobactam Sodium376.46.4
Dextrose186.36.3
Dextrose Monohydrate186.26.2
Erythropoietin276.16.1
Ruxolitinib865.65.6
Nintedanib375.45.5
Tobramycin Solution135.05.0
Febuxostat Tablets 40 Mg115.05.0
Febuxostat Tablets 80 Mg115.05.0
Deferasirox284.94.9
Tobramycin Sulfate134.84.8
Meropenem334.74.7
Metolazone114.54.5
Blinatumomab104.44.4
Tadalafil894.14.1
Dolutegravir Sodium84.14.1
Abiraterone124.14.1
Propofol324.04.0
Atovaquone74.04.0
Pancrelipase333.93.9
Temozolomide183.93.9
Sirolimus113.83.8
Sildenafil Citrate1023.73.7
Ursosiol153.53.5
Prochlorperazine Maleate73.53.5
Ursodiol163.43.4
Mycophenilic Acid153.33.3
Febuxostat123.33.3
Calcitriol Capsules 0.25 Mcg143.23.2
Calcitriol Capsules 0.5 Mcg143.23.2
Calcitriol143.23.2
Regorafenib83.23.2
Sodium Chloride Tablet503.13.1
Sodium Chloride Tablets503.13.1
Imatinib123.13.1
Niraparib153.13.1
Carfilzomib193.13.1
Umeclidinium63.13.1
Sodium Chloride523.03.0
Eltrombopag Olamine153.03.0
Sitagliptin And Metformin Hydrochloride143.03.0
Treprostinil803.03.0
Ivacaftor52.92.9
Rotigotine92.92.9
Fondaparinux Sodium52.82.8
Lutetium Lu 177 Vipivotide Tetraxetan82.82.8
Cytarabine362.82.8
Abemaciclib122.82.8
Teduglutide82.72.7
Ambrisentan732.72.7
Memantine82.72.7
Memantine Hydrochloride82.72.7
Thalidomide212.62.6
Trifluridine And Tipiracil62.62.6
Tolvaptan82.52.5
Vigabatrin82.52.5
Glecaprevir And Pibrentasvir62.52.5
Palivizumab82.42.4
Entecavir62.42.4
Droxidopa112.32.3
Eculizumab272.32.3
Timolol62.32.3
Levodopa62.32.3
Fam-Trastuzumab Deruxtecan-Nxki52.32.3
Acalabrutinib62.32.3
Durvalumab102.32.3
Brentuximab Vedotin52.22.2
Abiraterone Acetate202.22.2
Darbepoetin Alfa262.22.2
Nilotinib142.22.2
Ifosfamide102.12.1
Methadone Hydrochloride52.12.1
Pirfenidone182.02.0
Sevelamer Carbonate52.02.0
Baricitinib41.91.9
Belimumab131.91.9
Pomalidomide401.81.8
Dofetilide41.71.7
Enzalutamide221.71.7
Osimertinib121.71.7
Venetoclax231.71.7
Canakinumab41.71.7
Lenalidomide1531.71.7
Alpelisib31.61.6
Tafamidis41.61.6
Dextrose Monohydrate, Sodium Chloride, Sodium Lactate, Calcium Chloride, Magnesium Chloride31.61.6
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate141.61.6
Azacitidine101.51.5
Fentanyl Citrate61.51.5
Romiplostim51.51.5
Bictegravir Sodium, Emtricitabine, And Tenofovir Alafenamide Fumarate61.51.5
Elexacaftor, Tezacaftor, And Ivacaftor41.51.5
Dasatinib111.41.4
Pazopanib Hydrochloride81.41.4
Ixazomib81.31.3
Pimavanserin Tartrate141.21.2
Brexpiprazole41.11.1
Ledipasvir And Sofosbuvir41.01.0
Abaloparatide50.80.8
Valbenazine40.70.7
Cinacalcet Hydrochloride50.50.5

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Data source: openFDA FAERS. See the OpenPV methodology and limitations.