Reaction
Application Site Urticaria reporting signals
As of the last recalculation, Application Site Urticaria appears in 2,235 FAERS reports alongside 18 co-occurring drug terms. The strongest observed disproportionality signal is NICOTINE (PRR 127.7).
Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
| Drug | Co-reports | PRR | ROR |
|---|---|---|---|
| Nicotine | 445 | 127.7 | 129.1 |
| Methylphenidate | 140 | 48.0 | 48.2 |
| Buprenorphine | 205 | 22.6 | 22.7 |
| Estradiol | 188 | 22.0 | 22.1 |
| Crisaborole | 22 | 21.6 | 21.6 |
| Nicotine Polacrilex | 84 | 21.2 | 21.2 |
| Rotigotine | 29 | 18.9 | 18.9 |
| Nicotine Polacrilex Mini | 20 | 12.5 | 12.5 |
| Nicotine Polarilex | 20 | 12.5 | 12.5 |
| Estradiol Gel 0.1% | 47 | 9.9 | 9.9 |
| Estradiol Transdermal | 47 | 9.9 | 9.9 |
| Progesterone | 23 | 9.5 | 9.5 |
| Oxybutynin | 26 | 8.4 | 8.4 |
| Thyroid, Porcine | 7 | 6.1 | 6.1 |
| Minoxidil | 22 | 4.6 | 4.6 |
| Minoxidil Foam 5% (Womens) | 13 | 3.7 | 3.7 |
| Diclofenac Potassium | 4 | 3.5 | 3.5 |
| Salicylic Acid | 4 | 0.7 | 0.7 |