OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Progesterone

1,165 flagged reaction(s) · 100,377 total co-reports · max PRR 254.7
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Temperature Regulation Disorder 472 254.7 260.1 signal
2 Ovarian Hyperstimulation Syndrome 348 161.3 163.8 signal
3 Autoimmune Dermatitis 21 151.5 151.7 signal
4 Progesterone Decreased 36 120.8 121.0 signal
5 Food Allergy 607 80.6 82.8 signal
6 Placenta Accreta 17 78.9 78.9 signal
7 Fallopian Tube Disorder 23 77.2 77.2 signal
8 Blood Oestrogen Decreased 46 66.8 66.9 signal
9 Adnexal Torsion 20 62.1 62.1 signal
10 Foetal Death 304 57.4 58.2 signal
11 Premature Ageing 17 57.0 57.1 signal
12 Endometrial Thickening 29 51.8 51.9 signal
13 Ovarian Enlargement 20 50.1 50.1 signal
14 Keratoconus 17 44.4 44.4 signal
15 Postmenopausal Haemorrhage 118 44.2 44.4 signal
16 Congenital Umbilical Hernia 17 43.7 43.7 signal
17 Coeliac Disease 441 43.4 44.2 signal
18 Immunodeficiency 597 38.9 40.0 signal
19 Breast Hyperplasia 14 38.0 38.0 signal
20 Bursitis 450 35.7 36.4 signal
21 Butterfly Rash 37 35.3 35.4 signal
22 Endometrial Hyperplasia 30 35.3 35.3 signal
23 Plagiocephaly 18 34.3 34.3 signal
24 Abortion Threatened 18 34.1 34.1 signal
25 Disease Risk Factor 14 34.0 34.1 signal
26 Neonatal Asphyxia 25 33.7 33.7 signal
27 Endometrial Disorder 14 33.0 33.0 signal
28 Eosinophilic Pneumonia Acute 28 30.9 31.0 signal
29 Hypospadias 65 30.0 30.1 signal
30 Developmental Hip Dysplasia 24 27.3 27.3 signal
31 Blood Oestrogen Increased 16 26.2 26.2 signal
32 Hellp Syndrome 17 26.1 26.1 signal
33 Premature Labour 156 25.9 26.1 signal
34 Progesterone Receptor Assay Positive 25 25.0 25.1 signal
35 Breast Cancer In Situ 33 24.2 24.3 signal
36 Uterine Polyp 44 23.1 23.2 signal
37 Twin Pregnancy 20 22.4 22.4 signal
38 Prescribed Overdose 448 21.8 22.3 signal
39 Human Herpesvirus 6 Infection 44 21.8 21.8 signal
40 Preterm Premature Rupture Of Membranes 27 21.4 21.4 signal
41 Congenital Anomaly 174 21.0 21.2 signal
42 Congenital Hydronephrosis 16 21.0 21.0 signal
43 Oestrogen Receptor Assay Positive 25 20.5 20.6 signal
44 Menopausal Symptoms 49 20.2 20.3 signal
45 Ectopic Pregnancy 65 19.8 19.9 signal
46 Amniotic Cavity Infection 15 19.5 19.6 signal
47 Haemorrhage In Pregnancy 29 19.0 19.0 signal
48 Gestational Diabetes 91 18.2 18.3 signal
49 Premature Rupture Of Membranes 45 17.4 17.5 signal
50 Neonatal Respiratory Distress 16 17.3 17.3 signal
51 Menopause 47 17.3 17.3 signal
52 Bronchopulmonary Dysplasia 14 16.4 16.4 signal
53 Foetal Heart Rate Abnormal 16 16.2 16.2 signal
54 Hormone Level Abnormal 82 16.0 16.0 signal
55 Oligohydramnios 57 15.9 16.0 signal
56 Respiratory Disorder Neonatal 27 15.9 15.9 signal
57 Cryptorchism 19 15.9 15.9 signal
58 Atrial Septal Defect 142 15.8 15.9 signal
59 Death Neonatal 23 15.6 15.7 signal
60 Ventricular Septal Defect 91 14.8 14.8 signal
61 Exposure During Pregnancy 949 14.3 14.9 signal
62 Breast Tenderness 115 14.2 14.3 signal
63 Hepatic Necrosis 57 14.1 14.1 signal
64 Subclavian Vein Thrombosis 17 13.9 13.9 signal
65 Drug Exposure Before Pregnancy 15 13.8 13.8 signal
66 Haemangioma 34 13.7 13.7 signal
67 Hypotonia Neonatal 22 13.4 13.5 signal
68 Product Odour Abnormal 148 13.3 13.4 signal
69 Intermenstrual Bleeding 73 13.2 13.3 signal
70 Low Birth Weight Baby 108 12.7 12.7 signal
71 Upper Respiratory Tract Infection 623 12.6 12.9 signal
72 Contraindicated Product Administered 402 12.4 12.7 signal
73 Small For Dates Baby 66 12.4 12.4 signal
74 Pre-eclampsia 61 12.0 12.0 signal
75 Rash Erythematous 587 11.7 12.0 signal
76 Patent Ductus Arteriosus 50 11.7 11.7 signal
77 Intra-uterine Death 20 11.5 11.5 signal
78 Uterine Haemorrhage 52 11.4 11.4 signal
79 Product Adhesion Issue 432 11.4 11.6 signal
80 Premature Delivery 191 11.1 11.2 signal
81 Microcephaly 15 11.0 11.0 signal
82 Premature Baby 356 11.0 11.2 signal
83 Adnexa Uteri Pain 15 11.0 11.0 signal
84 Gestational Hypertension 15 10.9 10.9 signal
85 Neonatal Respiratory Distress Syndrome 41 10.8 10.8 signal
86 Maternal Exposure Before Pregnancy 77 10.6 10.6 signal
87 Pre-existing Condition Improved 71 10.5 10.5 signal
88 Foetal Exposure During Pregnancy 899 10.3 10.7 signal
89 Abortion Missed 14 10.2 10.2 signal
90 Fluid Retention 552 10.1 10.3 signal
91 Abortion Spontaneous 436 10.1 10.3 signal
92 Suspected Product Quality Issue 19 10.0 10.0 signal
93 Infertility 16 9.9 9.9 signal
94 Foetal Growth Restriction 62 9.6 9.6 signal
95 Uterine Disorder 24 9.5 9.5 signal
96 Application Site Urticaria 23 9.5 9.5 signal
97 Foetal Distress Syndrome 21 9.2 9.2 signal
98 Hepatic Enzyme Increased 672 9.2 9.5 signal
99 Terminal Insomnia 17 9.1 9.1 signal
100 Premature Separation Of Placenta 15 9.0 9.0 signal
101 Allergic Reaction To Excipient 19 9.0 9.0 signal
102 Polycystic Ovaries 15 8.9 8.9 signal
103 Vulvovaginal Discomfort 42 8.9 8.9 signal
104 Vaginal Haemorrhage 404 8.8 9.0 signal
105 Vaginal Discharge 95 8.8 8.8 signal
106 Poor Quality Product Administered 96 8.7 8.8 signal
107 Abortion 27 8.6 8.6 signal
108 Maternal Exposure During Pregnancy 803 8.5 8.7 signal
109 Endometrial Cancer 20 8.4 8.4 signal
110 Adrenal Disorder 17 8.2 8.2 signal
111 Talipes 27 8.1 8.1 signal
112 Breast Enlargement 28 7.9 7.9 signal
113 Breast Swelling 23 7.9 7.9 signal
114 Breast Cyst 15 7.8 7.8 signal
115 Application Site Rash 116 7.8 7.8 signal
116 Vulvovaginal Dryness 27 7.8 7.8 signal
117 Application Site Pruritus 190 7.8 7.8 signal
118 Breast Cancer Female 225 7.8 7.8 signal
119 Normal Newborn 45 7.7 7.7 signal
120 Joint Noise 16 7.7 7.7 signal
121 Periorbital Oedema 42 7.5 7.5 signal
122 Decreased Immune Responsiveness 79 7.5 7.5 signal
123 Maternal Exposure Timing Unspecified 30 7.5 7.5 signal
124 Nipple Pain 16 7.3 7.3 signal
125 Uterine Leiomyoma 57 7.2 7.2 signal
126 Blood Pressure Systolic Abnormal 19 7.1 7.1 signal
127 Abnormal Uterine Bleeding 19 7.1 7.1 signal
128 Live Birth 63 7.0 7.0 signal
129 Suicidal Behaviour 31 6.9 6.9 signal
130 Infusion Related Reaction 489 6.9 7.0 signal
131 Reaction To Excipient 17 6.9 6.9 signal
132 Fine Motor Skill Dysfunction 21 6.8 6.8 signal
133 Chronic Sinusitis 27 6.7 6.7 signal
134 Product Administration Interrupted 55 6.7 6.7 signal
135 Blood Pressure Diastolic Increased 33 6.6 6.6 signal
136 Infusion Site Bruising 15 6.5 6.5 signal
137 Eosinophilic Pneumonia 22 6.5 6.5 signal
138 Breast Pain 74 6.4 6.5 signal
139 Speech Disorder Developmental 20 6.4 6.4 signal
140 Endometriosis 33 6.4 6.4 signal
141 Hordeolum 29 6.4 6.4 signal
142 Caesarean Section 80 6.3 6.3 signal
143 Ovarian Cyst 68 6.3 6.3 signal
144 Application Site Irritation 84 6.3 6.3 signal
145 Breast Cancer Metastatic 71 6.1 6.2 signal
146 Blood Pressure Diastolic Abnormal 17 6.1 6.1 signal
147 Pregnancy 133 6.1 6.1 signal
148 Hyperhidrosis 836 6.0 6.2 signal
149 Metrorrhagia 111 6.0 6.0 signal
150 Asthma 716 5.9 6.1 signal
151 Application Site Erythema 168 5.9 6.0 signal
152 Infusion Site Swelling 39 5.9 5.9 signal
153 Hot Flush 475 5.8 5.9 signal
154 Infusion Site Haemorrhage 20 5.7 5.7 signal
155 Rheumatoid Arthritis 692 5.7 5.8 signal
156 Hepatic Encephalopathy 57 5.7 5.7 signal
157 Maternal Drugs Affecting Foetus 47 5.6 5.6 signal
158 Product Contamination Physical 15 5.6 5.6 signal
159 Heavy Menstrual Bleeding 48 5.6 5.6 signal
160 Attention Deficit Hyperactivity Disorder 25 5.6 5.6 signal
161 Urinary Tract Infection Bacterial 15 5.5 5.5 signal
162 Electric Shock Sensation 16 5.5 5.5 signal
163 Brain Fog 86 5.5 5.5 signal
164 Autoimmune Thyroiditis 22 5.4 5.4 signal
165 Bruxism 31 5.3 5.3 signal
166 Application Site Swelling 28 5.2 5.2 signal
167 Invasive Ductal Breast Carcinoma 15 5.1 5.1 signal
168 Intentional Product Misuse 476 5.1 5.2 signal
169 Infusion Site Pruritus 17 5.1 5.1 signal
170 Therapeutic Reaction Time Decreased 16 5.0 5.0 signal
171 Night Sweats 174 5.0 5.0 signal
172 Feeling Drunk 39 4.8 4.8 signal
173 Ear Congestion 14 4.8 4.8 signal
174 Application Site Discolouration 21 4.8 4.8 signal
175 Breast Mass 34 4.7 4.7 signal
176 Plantar Fasciitis 17 4.7 4.7 signal
177 Hysterectomy 43 4.6 4.6 signal
178 Polymenorrhoea 16 4.6 4.6 signal
179 Joint Swelling 595 4.6 4.7 signal
180 Breast Cancer 463 4.6 4.6 signal
181 Multiple-drug Resistance 15 4.5 4.5 signal
182 Blood Thyroid Stimulating Hormone Decreased 22 4.5 4.5 signal
183 Lyme Disease 16 4.5 4.5 signal
184 Snoring 18 4.4 4.4 signal
185 Congestive Cardiomyopathy 20 4.4 4.4 signal
186 Umbilical Hernia 22 4.3 4.3 signal
187 Product Substitution Issue 270 4.3 4.4 signal
188 Hypersensitivity 868 4.3 4.5 signal
189 Recalled Product Administered 41 4.3 4.3 signal
190 Application Site Burn 23 4.3 4.3 signal
191 Depression Suicidal 16 4.3 4.3 signal
192 Intervertebral Disc Degeneration 43 4.3 4.3 signal
193 Maternal Exposure During Breast Feeding 18 4.2 4.3 signal
194 Onychomycosis 20 4.2 4.2 signal
195 Nerve Compression 42 4.2 4.2 signal
196 Hyperacusis 17 4.2 4.2 signal
197 Head Discomfort 80 4.2 4.2 signal
198 Retching 96 4.2 4.2 signal
199 Rhinitis Allergic 20 4.2 4.2 signal
200 Iron Deficiency 20 4.2 4.2 signal
201 Hair Growth Abnormal 31 4.1 4.1 signal
202 Bladder Pain 14 4.1 4.1 signal
203 Meniscus Injury 27 4.1 4.1 signal
204 Drug Effect Increased 14 4.0 4.0 signal
205 Drug Tolerance 22 4.0 4.0 signal
206 Seasonal Allergy 61 4.0 4.0 signal
207 Skin Odour Abnormal 17 4.0 4.0 signal
208 Erythema Nodosum 15 4.0 4.0 signal
209 Dysmenorrhoea 56 4.0 4.0 signal
210 Depressive Symptom 15 3.9 4.0 signal
211 Glucose Tolerance Impaired 25 3.9 3.9 signal
212 Vaginal Infection 20 3.9 3.9 signal
213 Hangover 15 3.9 3.9 signal
214 Drug Intolerance 407 3.9 4.0 signal
215 Drug Exposure During Pregnancy 145 3.9 3.9 signal
216 Fibromyalgia 102 3.9 3.9 signal
217 Product Use Issue 785 3.9 4.0 signal
218 Sleep Apnoea Syndrome 80 3.9 3.9 signal
219 Post-traumatic Stress Disorder 28 3.9 3.9 signal
220 Vulvovaginal Pruritus 21 3.8 3.9 signal
221 Poor Quality Sleep 88 3.8 3.8 signal
222 Application Site Exfoliation 17 3.8 3.8 signal
223 Vulvovaginal Mycotic Infection 16 3.8 3.8 signal
224 Photosensitivity Reaction 67 3.8 3.8 signal
225 Middle Insomnia 75 3.7 3.7 signal
226 Menstrual Disorder 33 3.7 3.7 signal
227 Paranasal Sinus Discomfort 15 3.7 3.7 signal
228 Migraine 376 3.7 3.7 signal
229 Streptococcal Infection 22 3.7 3.7 signal
230 Neurological Symptom 22 3.6 3.6 signal
231 Stress Fracture 21 3.6 3.6 signal
232 Infusion Site Erythema 32 3.6 3.6 signal
233 Food Intolerance 14 3.5 3.5 signal
234 Therapeutic Product Ineffective 15 3.5 3.5 signal
235 Meningioma 56 3.5 3.5 signal
236 Vitamin D Deficiency 37 3.5 3.5 signal
237 Product Formulation Issue 25 3.5 3.5 signal
238 Vulvovaginal Burning Sensation 23 3.5 3.5 signal
239 Hereditary Angioedema 39 3.4 3.4 signal
240 Stillbirth 18 3.4 3.4 signal
241 Dyspareunia 17 3.4 3.4 signal
242 Tendon Pain 28 3.4 3.4 signal
243 Device Adhesion Issue 56 3.4 3.4 signal
244 Thrombocytopenia 409 3.4 3.4 signal
245 Malabsorption 19 3.4 3.4 signal
246 Oral Herpes 71 3.4 3.4 signal
247 Melanocytic Naevus 16 3.4 3.4 signal
248 Treatment Failure 298 3.4 3.4 signal
249 Thinking Abnormal 68 3.4 3.4 signal
250 Drug Hypersensitivity 703 3.3 3.4 signal
251 Hepatotoxicity 80 3.3 3.3 signal
252 Abortion Induced 34 3.3 3.3 signal
253 Infusion Site Pain 46 3.3 3.3 signal
254 Hypothyroidism 114 3.3 3.3 signal
255 Neuralgia 85 3.2 3.2 signal
256 Constipation 758 3.2 3.3 signal
257 Insurance Issue 52 3.2 3.2 signal
258 Tinnitus 160 3.2 3.2 signal
259 Multiple Allergies 27 3.2 3.2 signal
260 Back Pain 795 3.2 3.2 signal
261 Symptom Recurrence 20 3.2 3.2 signal
262 Spinal Osteoarthritis 30 3.1 3.1 signal
263 Restless Legs Syndrome 61 3.1 3.1 signal
264 Onychoclasis 23 3.1 3.1 signal
265 Dermatitis Contact 38 3.1 3.1 signal
266 Vulvovaginal Pain 16 3.1 3.1 signal
267 Headache 2,089 3.1 3.3 signal
268 Hepatic Cirrhosis 62 3.1 3.1 signal
269 Drug-induced Liver Injury 102 3.1 3.1 signal
270 Cyst 41 3.0 3.1 signal
271 Tricuspid Valve Incompetence 26 3.0 3.0 signal
272 Sinusitis 338 3.0 3.1 signal
273 Psoriasis 429 3.0 3.1 signal
274 Abdominal Pain Lower 83 3.0 3.0 signal
275 Mucous Stools 16 3.0 3.0 signal
276 Madarosis 38 3.0 3.0 signal
277 Cardiac Flutter 21 3.0 3.0 signal
278 Hypertension 686 3.0 3.1 signal
279 Impaired Gastric Emptying 41 3.0 3.0 signal
280 Foot Fracture 61 3.0 3.0 signal
281 Foot Deformity 35 2.9 2.9 signal
282 Erythema 647 2.9 3.0 signal
283 Tendonitis 49 2.9 2.9 signal
284 Mood Swings 100 2.9 2.9 signal
285 Pelvic Pain 57 2.9 2.9 signal
286 Panic Attack 114 2.9 2.9 signal
287 Asthenopia 17 2.9 2.9 signal
288 Disease Recurrence 149 2.9 2.9 signal
289 Hyperthyroidism 45 2.9 2.9 signal
290 Abdominal Distension 322 2.9 2.9 signal
291 Gastroenteritis Viral 56 2.9 2.9 signal
292 Ligament Sprain 30 2.8 2.8 signal
293 Somnambulism 20 2.8 2.8 signal
294 Eye Infection 34 2.8 2.8 signal
295 Crying 110 2.8 2.8 signal
296 Osteopenia 46 2.8 2.8 signal
297 Formication 21 2.8 2.8 signal
298 Intervertebral Disc Protrusion 66 2.8 2.8 signal
299 Exostosis 27 2.7 2.7 signal
300 Tooth Infection 39 2.7 2.7 signal
301 Insomnia 784 2.7 2.8 signal
302 Feeling Jittery 56 2.7 2.7 signal
303 Therapeutic Response Unexpected 132 2.7 2.7 signal
304 Hypercholesterolaemia 28 2.7 2.7 signal
305 Skin Warm 17 2.7 2.7 signal
306 Body Temperature Decreased 29 2.7 2.7 signal
307 Myasthenia Gravis 23 2.7 2.7 signal
308 Eye Pain 161 2.7 2.7 signal
309 Ovarian Cancer 27 2.7 2.7 signal
310 Micturition Urgency 33 2.7 2.7 signal
311 Muscle Strain 25 2.7 2.7 signal
312 Blood Iron Decreased 34 2.7 2.7 signal
313 Tonsillitis 15 2.7 2.7 signal
314 Ocular Discomfort 31 2.6 2.6 signal
315 Photopsia 18 2.6 2.6 signal
316 Paraesthesia Oral 41 2.6 2.6 signal
317 Psychiatric Symptom 21 2.6 2.6 signal
318 Drug Effect Less Than Expected 40 2.6 2.6 signal
319 Hunger 38 2.6 2.6 signal
320 Ascites 83 2.6 2.6 signal
321 Application Site Pain 62 2.6 2.6 signal
322 Poor Venous Access 29 2.6 2.6 signal
323 Thyroid Disorder 43 2.6 2.6 signal
324 Dry Eye 135 2.6 2.6 signal
325 Nerve Injury 31 2.6 2.6 signal
326 Limb Discomfort 86 2.6 2.6 signal
327 Panic Reaction 20 2.6 2.6 signal
328 Vitreous Floaters 27 2.6 2.6 signal
329 Product Physical Issue 55 2.5 2.6 signal
330 Heart Rate Increased 273 2.5 2.6 signal
331 Polyp 18 2.5 2.5 signal
332 Scar 47 2.5 2.5 signal
333 Infusion Site Extravasation 17 2.5 2.5 signal
334 Pharyngeal Swelling 26 2.5 2.5 signal
335 Anal Incontinence 24 2.5 2.5 signal
336 Wrist Fracture 32 2.5 2.5 signal
337 Neck Pain 149 2.5 2.5 signal
338 Diverticulitis 73 2.4 2.4 signal
339 Palpitations 306 2.4 2.4 signal
340 Mood Altered 71 2.4 2.4 signal
341 Nodule 34 2.4 2.4 signal
342 Ear Infection 69 2.4 2.4 signal
343 Disturbance In Attention 140 2.4 2.4 signal
344 Bradyphrenia 17 2.4 2.4 signal
345 Skin Swelling 22 2.4 2.4 signal
346 Arthropod Bite 19 2.4 2.4 signal
347 Concussion 20 2.4 2.4 signal
348 Laryngitis 28 2.4 2.4 signal
349 Facial Pain 23 2.4 2.4 signal
350 Scoliosis 16 2.4 2.4 signal
351 Amenorrhoea 43 2.4 2.4 signal
352 Sinus Disorder 51 2.4 2.4 signal
353 Depressed Mood 135 2.4 2.4 signal
354 Upper-airway Cough Syndrome 21 2.4 2.4 signal
355 Menorrhagia 51 2.4 2.4 signal
356 Fungal Infection 85 2.4 2.4 signal
357 Nasal Dryness 16 2.4 2.4 signal
358 Initial Insomnia 26 2.4 2.4 signal
359 Peripheral Coldness 35 2.3 2.3 signal
360 Application Site Reaction 18 2.3 2.3 signal
361 Metastases To Lymph Nodes 17 2.3 2.3 signal
362 Stress 182 2.3 2.3 signal
363 Infection 364 2.3 2.4 signal
364 Anxiety 716 2.3 2.4 signal
365 Diverticulum 18 2.3 2.3 signal
366 Foreign Body In Reproductive Tract 22 2.3 2.3 signal
367 Aphthous Ulcer 19 2.3 2.3 signal
368 Muscle Tightness 40 2.3 2.3 signal
369 Tongue Disorder 18 2.3 2.3 signal
370 Herpes Simplex 16 2.3 2.3 signal
371 Oropharyngeal Pain 228 2.3 2.3 signal
372 Covid-19 434 2.3 2.3 signal
373 Temperature Intolerance 25 2.3 2.3 signal
374 Gastrooesophageal Reflux Disease 196 2.3 2.3 signal
375 Joint Stiffness 64 2.3 2.3 signal
376 Blood Pressure Diastolic Decreased 18 2.2 2.2 signal
377 Respiratory Tract Infection 63 2.2 2.2 signal
378 Overdose 523 2.2 2.3 signal
379 Swelling Face 157 2.2 2.2 signal
380 Abnormal Dreams 67 2.2 2.2 signal
381 Weight Increased 536 2.2 2.3 signal
382 Foreign Body Sensation In Eyes 15 2.2 2.2 signal
383 Pain 1,477 2.2 2.3 signal
384 Candida Infection 40 2.2 2.2 signal
385 Kidney Infection 47 2.2 2.2 signal
386 Iron Deficiency Anaemia 22 2.2 2.2 signal
387 Bronchitis 178 2.2 2.2 signal
388 Intentional Dose Omission 65 2.2 2.2 signal
389 Product Quality Issue 320 2.2 2.2 signal
390 Blood Pressure Fluctuation 57 2.2 2.2 signal
391 Renal Pain 25 2.2 2.2 signal
392 Feeling Abnormal 567 2.2 2.2 signal
393 Product Administration Error 47 2.2 2.2 signal
394 Labelled Drug-drug Interaction Medication Error 21 2.2 2.2 signal
395 Gallbladder Disorder 42 2.2 2.2 signal
396 Vertigo 143 2.2 2.2 signal
397 Irritable Bowel Syndrome 50 2.2 2.2 signal
398 Embedded Device 23 2.2 2.2 signal
399 Feeling Cold 65 2.2 2.2 signal
400 Rotator Cuff Syndrome 30 2.1 2.2 signal
401 Musculoskeletal Chest Pain 36 2.1 2.1 signal
402 Depression 530 2.1 2.2 signal
403 Hepatic Steatosis 43 2.1 2.1 signal
404 Fatigue 1,793 2.1 2.2 signal
405 Hyperprolactinaemia 15 2.1 2.1 signal
406 Autoimmune Disorder 22 2.1 2.1 signal
407 Intentional Product Use Issue 202 2.1 2.1 signal
408 Impaired Quality Of Life 33 2.1 2.1 signal
409 Emotional Disorder 71 2.1 2.1 signal
410 Feeling Hot 140 2.1 2.1 signal
411 Carpal Tunnel Syndrome 32 2.1 2.1 signal
412 Tooth Fracture 25 2.1 2.1 signal
413 Injection Site Urticaria 55 2.1 2.1 signal
414 Rash 982 2.1 2.1 signal
415 Surgery 131 2.1 2.1 signal
416 Cystitis 72 2.1 2.1 signal
417 Eye Discharge 23 2.1 2.1 signal
418 Photophobia 42 2.1 2.1 signal
419 Deformity 21 2.1 2.1 signal
420 Osteoarthritis 95 2.1 2.1 signal
421 Rhinitis 18 2.1 2.1 signal
422 Product Taste Abnormal 30 2.1 2.1 signal
423 Obsessive-compulsive Disorder 18 2.1 2.1 signal
424 Muscle Spasms 409 2.1 2.1 signal
425 Nasal Congestion 130 2.1 2.1 signal
426 Visual Field Defect 16 2.0 2.0 signal
427 Therapy Cessation 113 2.0 2.0 signal
428 Bladder Disorder 22 2.0 2.0 signal
429 Discomfort 134 2.0 2.0 signal
430 Pyelonephritis 19 2.0 2.0 signal
431 Impaired Driving Ability 25 2.0 2.0 signal
432 Product Use Complaint 34 2.0 2.0 signal
433 Irritability 132 2.0 2.0 signal
434 Gastrointestinal Pain 24 2.0 2.0 signal
435 Heart Rate Decreased 77 2.0 2.0 signal
436 Burning Sensation 153 2.0 2.0 signal
437 Dermatitis Atopic 109 2.0 2.0 signal
438 Hyperaesthesia 18 2.0 2.0 signal
439 Affect Lability 21 2.0 2.0 signal
440 Large Intestine Polyp 15 2.0 2.0 no signal
441 Muscle Twitching 50 2.0 2.0 no signal
442 Quality Of Life Decreased 29 2.0 2.0 no signal
443 Ear Discomfort 22 2.0 2.0 no signal
444 Throat Tightness 58 2.0 2.0 no signal
445 Impaired Work Ability 46 2.0 2.0 no signal
446 Sleep Disorder 150 2.0 2.0 no signal
447 Hyperbilirubinaemia 22 2.0 2.0 no signal
448 Mitral Valve Incompetence 24 2.0 2.0 no signal
449 Nervousness 111 2.0 2.0 no signal
450 Dry Mouth 171 1.9 2.0 no signal
451 Tenderness 22 1.9 1.9 no signal
452 Off Label Use 1,828 1.9 2.0 no signal
453 Vision Blurred 287 1.9 2.0 no signal
454 Colitis Ischaemic 14 1.9 1.9 no signal
455 Hiatus Hernia 27 1.9 1.9 no signal
456 Pyrexia 720 1.9 2.0 no signal
457 Swollen Tongue 65 1.9 1.9 no signal
458 Sinus Congestion 28 1.9 1.9 no signal
459 Alopecia 406 1.9 1.9 no signal
460 Cholecystitis Chronic 14 1.9 1.9 no signal
461 Hypertensive Crisis 23 1.9 1.9 no signal
462 Product Use In Unapproved Indication 503 1.9 1.9 no signal
463 Blood Thyroid Stimulating Hormone Increased 19 1.9 1.9 no signal
464 Joint Injury 44 1.9 1.9 no signal
465 Gastritis 54 1.9 1.9 no signal
466 Blood Calcium Increased 18 1.9 1.9 no signal
467 Affective Disorder 16 1.9 1.9 no signal
468 Illness 205 1.9 1.9 no signal
469 Skin Laceration 22 1.9 1.9 no signal
470 Product Distribution Issue 18 1.9 1.9 no signal
471 Injection Site Pruritus 135 1.9 1.9 no signal
472 Sensation Of Foreign Body 17 1.9 1.9 no signal
473 Thirst 36 1.9 1.9 no signal
474 Weight Fluctuation 21 1.9 1.9 no signal
475 Frequent Bowel Movements 54 1.9 1.9 no signal
476 Therapeutic Product Effect Decreased 89 1.9 1.9 no signal
477 Oral Candidiasis 26 1.8 1.8 no signal
478 Paraesthesia 315 1.8 1.9 no signal
479 Chills 234 1.8 1.8 no signal
480 Hypersomnia 57 1.8 1.8 no signal
481 Throat Irritation 89 1.8 1.8 no signal
482 Vitamin D Decreased 17 1.8 1.8 no signal
483 Spinal Operation 24 1.8 1.8 no signal
484 Dysgeusia 148 1.8 1.8 no signal
485 Nocturia 24 1.8 1.8 no signal
486 Eyelid Ptosis 20 1.8 1.8 no signal
487 Hidradenitis 17 1.8 1.8 no signal
488 Eye Irritation 109 1.8 1.8 no signal
489 Mydriasis 25 1.8 1.8 no signal
490 Swelling 182 1.8 1.8 no signal
491 Respiratory Tract Congestion 31 1.8 1.8 no signal
492 Mania 32 1.8 1.8 no signal
493 Dyspepsia 191 1.8 1.8 no signal
494 Flatulence 110 1.8 1.8 no signal
495 Urticaria 323 1.8 1.8 no signal
496 Libido Decreased 24 1.8 1.8 no signal
497 Ankle Fracture 30 1.8 1.8 no signal
498 Nasopharyngitis 356 1.8 1.8 no signal
499 Urinary Incontinence 57 1.8 1.8 no signal
500 Ventricular Extrasystoles 20 1.8 1.8 no signal
501 Gastroenteritis 28 1.8 1.8 no signal
502 Hyperlipidaemia 23 1.8 1.8 no signal
503 Sleep Disorder Due To A General Medical Condition 31 1.8 1.8 no signal
504 Procedural Pain 53 1.8 1.8 no signal
505 Somnolence 384 1.8 1.8 no signal
506 Gastrointestinal Infection 17 1.8 1.8 no signal
507 Haemorrhoids 37 1.7 1.7 no signal
508 Eructation 36 1.7 1.7 no signal
509 Blood Pressure Systolic Increased 37 1.7 1.7 no signal
510 Dizziness 937 1.7 1.8 no signal
511 Aphasia 57 1.7 1.7 no signal
512 Dizziness Postural 18 1.7 1.7 no signal
513 Product Administered At Inappropriate Site 34 1.7 1.7 no signal
514 Frustration Tolerance Decreased 15 1.7 1.7 no signal
515 Nausea 1,471 1.7 1.8 no signal
516 Increased Appetite 35 1.7 1.7 no signal
517 Rhinorrhoea 120 1.7 1.7 no signal
518 Sensory Loss 15 1.7 1.7 no signal
519 Anger 63 1.7 1.7 no signal
520 Hair Texture Abnormal 25 1.7 1.7 no signal
521 Arthralgia 767 1.7 1.7 no signal
522 Uterine Cancer 15 1.7 1.7 no signal
523 Upper Limb Fracture 37 1.7 1.7 no signal
524 Cholecystectomy 21 1.7 1.7 no signal
525 Paranoia 32 1.7 1.7 no signal
526 Pharyngitis Streptococcal 20 1.7 1.7 no signal
527 Back Injury 20 1.7 1.7 no signal
528 Pharyngitis 23 1.7 1.7 no signal
529 Blood Cholesterol Increased 86 1.7 1.7 no signal
530 Euphoric Mood 19 1.7 1.7 no signal
531 Ankylosing Spondylitis 24 1.7 1.7 no signal
532 Contusion 177 1.7 1.7 no signal
533 Influenza Like Illness 152 1.7 1.7 no signal
534 Adrenal Insufficiency 22 1.7 1.7 no signal
535 Lymphadenopathy 65 1.7 1.7 no signal
536 Product Availability Issue 41 1.7 1.7 no signal
537 Suicidal Ideation 167 1.7 1.7 no signal
538 Cataract 108 1.7 1.7 no signal
539 Abdominal Pain 423 1.7 1.7 no signal
540 Groin Pain 16 1.7 1.7 no signal
541 Chromaturia 41 1.7 1.7 no signal
542 Blood Pressure Increased 278 1.7 1.7 no signal
543 Lacrimation Increased 54 1.7 1.7 no signal
544 Abdominal Pain Upper 371 1.7 1.7 no signal
545 Withdrawal Syndrome 76 1.7 1.7 no signal
546 Cholelithiasis 59 1.7 1.7 no signal
547 Sneezing 40 1.7 1.7 no signal
548 Injection Site Discolouration 22 1.6 1.6 no signal
549 Decreased Activity 19 1.6 1.6 no signal
550 Limb Injury 48 1.6 1.6 no signal
551 Eczema 89 1.6 1.6 no signal
552 Facial Paralysis 15 1.6 1.6 no signal
553 Pollakiuria 73 1.6 1.6 no signal
554 Flushing 179 1.6 1.6 no signal
555 Arthritis 138 1.6 1.6 no signal
556 Ear Pain 34 1.6 1.6 no signal
557 Osteoporosis 72 1.6 1.6 no signal
558 Atrial Flutter 14 1.6 1.6 no signal
559 Hypokalaemia 80 1.6 1.6 no signal
560 Hypoaesthesia 261 1.6 1.6 no signal
561 Cognitive Disorder 81 1.6 1.6 no signal
562 Injection Site Irritation 22 1.6 1.6 no signal
563 Presyncope 42 1.6 1.6 no signal
564 Increased Tendency To Bruise 16 1.6 1.6 no signal
565 Petechiae 18 1.6 1.6 no signal
566 Blood Potassium Decreased 52 1.6 1.6 no signal
567 Product Packaging Issue 16 1.6 1.6 no signal
568 Cardiac Murmur 15 1.6 1.6 no signal
569 Aphonia 24 1.6 1.6 no signal
570 Personality Change 16 1.6 1.6 no signal
571 Complication Of Device Removal 29 1.6 1.6 no signal
572 Skin Reaction 24 1.6 1.6 no signal
573 Generalised Oedema 21 1.6 1.6 no signal
574 Salivary Hypersecretion 17 1.6 1.6 no signal
575 Urinary Tract Infection 289 1.6 1.6 no signal
576 Injection Site Induration 22 1.6 1.6 no signal
577 Fear 46 1.6 1.6 no signal
578 Tendon Rupture 21 1.6 1.6 no signal
579 Hypotonia 17 1.6 1.6 no signal
580 Pruritus 640 1.6 1.6 no signal
581 Obesity 27 1.6 1.6 no signal
582 Rash Papular 38 1.6 1.6 no signal
583 Psoriatic Arthropathy 68 1.6 1.6 no signal
584 Muscular Weakness 192 1.6 1.6 no signal
585 Product Prescribing Error 40 1.6 1.6 no signal
586 Abdominal Discomfort 282 1.6 1.6 no signal
587 Loss Of Personal Independence In Daily Activities 80 1.6 1.6 no signal
588 Heart Rate Irregular 38 1.5 1.5 no signal
589 Loss Of Libido 15 1.5 1.5 no signal
590 Chest Discomfort 169 1.5 1.5 no signal
591 Herpes Zoster 95 1.5 1.5 no signal
592 Eye Swelling 61 1.5 1.5 no signal
593 Joint Range Of Motion Decreased 22 1.5 1.5 no signal
594 Eating Disorder 35 1.5 1.5 no signal
595 Dysphonia 95 1.5 1.5 no signal
596 Lethargy 93 1.5 1.5 no signal
597 Joint Dislocation 17 1.5 1.5 no signal
598 Muscle Spasticity 20 1.5 1.5 no signal
599 Mental Impairment 39 1.5 1.5 no signal
600 Incontinence 17 1.5 1.5 no signal
601 Leukopenia 80 1.5 1.5 no signal
602 Therapeutic Response Shortened 51 1.5 1.5 no signal
603 Paralysis 23 1.5 1.5 no signal
604 Bedridden 21 1.5 1.5 no signal
605 Injection Site Reaction 109 1.5 1.5 no signal
606 Hyponatraemia 89 1.5 1.5 no signal
607 Nightmare 55 1.5 1.5 no signal
608 Oral Discomfort 22 1.5 1.5 no signal
609 Dry Throat 16 1.5 1.5 no signal
610 Wrong Technique In Product Usage Process 318 1.5 1.5 no signal
611 Nephrolithiasis 72 1.5 1.5 no signal
612 Drug Effect Decreased 86 1.5 1.5 no signal
613 Injection Site Mass 58 1.5 1.5 no signal
614 Coordination Abnormal 22 1.4 1.4 no signal
615 Tooth Abscess 16 1.4 1.4 no signal
616 Bacterial Infection 29 1.4 1.4 no signal
617 Inflammation 80 1.4 1.4 no signal
618 Product Packaging Quantity Issue 17 1.4 1.4 no signal
619 Oesophagitis 17 1.4 1.4 no signal
620 Bipolar Disorder 17 1.4 1.4 no signal
621 Pain In Extremity 458 1.4 1.4 no signal
622 Sensory Disturbance 25 1.4 1.4 no signal
623 Injection Site Rash 47 1.4 1.4 no signal
624 Balance Disorder 134 1.4 1.4 no signal
625 Toothache 28 1.4 1.4 no signal
626 Myalgia 263 1.4 1.4 no signal
627 Influenza 173 1.4 1.4 no signal
628 Eye Pruritus 51 1.4 1.4 no signal
629 Amnesia 101 1.4 1.4 no signal
630 Dermatitis 32 1.4 1.4 no signal
631 Memory Impairment 212 1.4 1.4 no signal
632 Tremor 256 1.4 1.4 no signal
633 Diplopia 40 1.4 1.4 no signal
634 Drug Prescribing Error 30 1.4 1.4 no signal
635 Injection Site Erythema 190 1.4 1.4 no signal
636 Developmental Delay 14 1.4 1.4 no signal
637 Lip Swelling 51 1.4 1.4 no signal
638 Viral Infection 51 1.4 1.4 no signal
639 Unevaluable Event 116 1.4 1.4 no signal
640 Cardiomegaly 19 1.4 1.4 no signal
641 Musculoskeletal Stiffness 134 1.4 1.4 no signal
642 Restlessness 56 1.4 1.4 no signal
643 Incorrect Product Administration Duration 31 1.4 1.4 no signal
644 Cellulitis 77 1.4 1.4 no signal
645 Anosmia 22 1.4 1.4 no signal
646 Inappropriate Schedule Of Product Administration 268 1.4 1.4 no signal
647 Apathy 22 1.4 1.4 no signal
648 Sciatica 24 1.4 1.4 no signal
649 Rash Pruritic 81 1.4 1.4 no signal
650 Flank Pain 14 1.4 1.4 no signal
651 Economic Problem 23 1.4 1.4 no signal
652 Orthostatic Hypotension 26 1.4 1.4 no signal
653 Product Dose Omission In Error 40 1.4 1.4 no signal
654 Incorrect Route Of Product Administration 25 1.4 1.4 no signal
655 Squamous Cell Carcinoma 14 1.4 1.4 no signal
656 Skin Fissures 28 1.4 1.4 no signal
657 Chest Pain 275 1.4 1.4 no signal
658 Sluggishness 15 1.4 1.4 no signal
659 Aspiration 16 1.4 1.4 no signal
660 Product Prescribing Issue 30 1.4 1.4 no signal
661 Cold Sweat 26 1.4 1.4 no signal
662 Wound Infection 16 1.4 1.4 no signal
663 Gastrointestinal Disorder 130 1.4 1.4 no signal
664 Injection Site Nodule 16 1.3 1.3 no signal
665 Post Procedural Complication 28 1.3 1.3 no signal
666 Injection Site Discomfort 15 1.3 1.3 no signal
667 Eyelid Oedema 17 1.3 1.3 no signal
668 Product Dose Omission Issue 413 1.3 1.3 no signal
669 Dental Caries 16 1.3 1.3 no signal
670 Weight Decreased 403 1.3 1.3 no signal
671 Dermatitis Allergic 18 1.3 1.3 no signal
672 Choking 28 1.3 1.3 no signal
673 Knee Operation 14 1.3 1.3 no signal
674 Injection Site Swelling 109 1.3 1.3 no signal
675 Bone Pain 84 1.3 1.3 no signal
676 Blood Test Abnormal 20 1.3 1.3 no signal
677 Drug Interaction 226 1.3 1.3 no signal
678 Sars-cov-2 Test Positive 19 1.3 1.3 no signal
679 Disability 28 1.3 1.3 no signal
680 Lymphocyte Count Decreased 25 1.3 1.3 no signal
681 Ocular Hyperaemia 66 1.3 1.3 no signal
682 Cough 395 1.3 1.3 no signal
683 Dysuria 52 1.3 1.3 no signal
684 Back Disorder 23 1.3 1.3 no signal
685 Pain Of Skin 38 1.3 1.3 no signal
686 Rash Macular 49 1.3 1.3 no signal
687 Gait Disturbance 270 1.3 1.3 no signal
688 Drug Ineffective For Unapproved Indication 78 1.3 1.3 no signal
689 Brain Injury 14 1.3 1.3 no signal
690 Dysphagia 132 1.3 1.3 no signal
691 Deep Vein Thrombosis 91 1.3 1.3 no signal
692 Genital Haemorrhage 18 1.3 1.3 no signal
693 Knee Arthroplasty 29 1.3 1.3 no signal
694 Diarrhoea Haemorrhagic 13 1.3 1.3 no signal
695 Body Height Decreased 15 1.3 1.3 no signal
696 Haemorrhage 145 1.3 1.3 no signal
697 Skin Disorder 46 1.3 1.3 no signal
698 Eye Inflammation 13 1.3 1.3 no signal
699 Sputum Discoloured 13 1.3 1.3 no signal
700 Device Breakage 54 1.3 1.3 no signal
701 Central Nervous System Lesion 19 1.3 1.3 no signal
702 Multiple Sclerosis 66 1.3 1.3 no signal
703 Condition Aggravated 414 1.3 1.3 no signal
704 Malaise 600 1.3 1.3 no signal
705 Multiple Organ Dysfunction Syndrome 38 1.3 1.3 no signal
706 Injection Site Warmth 28 1.3 1.3 no signal
707 Supraventricular Tachycardia 13 1.3 1.3 no signal
708 Adverse Reaction 18 1.3 1.3 no signal
709 Blood Triglycerides Increased 24 1.2 1.2 no signal
710 Product Preparation Error 28 1.2 1.2 no signal
711 Cardiomyopathy 20 1.2 1.2 no signal
712 Hair Colour Changes 17 1.2 1.2 no signal
713 Hemiparesis 23 1.2 1.2 no signal
714 Cholecystitis 16 1.2 1.2 no signal
715 Drug Ineffective 1,772 1.2 1.3 no signal
716 Pulmonary Mass 20 1.2 1.2 no signal
717 Basal Cell Carcinoma 21 1.2 1.2 no signal
718 Skin Infection 15 1.2 1.2 no signal
719 Tooth Disorder 30 1.2 1.2 no signal
720 Musculoskeletal Discomfort 23 1.2 1.2 no signal
721 Dysstasia 39 1.2 1.2 no signal
722 Hypoaesthesia Oral 20 1.2 1.2 no signal
723 Musculoskeletal Pain 70 1.2 1.2 no signal
724 Coagulopathy 22 1.2 1.2 no signal
725 Pulmonary Embolism 126 1.2 1.2 no signal
726 Hip Arthroplasty 20 1.2 1.2 no signal
727 Skin Haemorrhage 19 1.2 1.2 no signal
728 Therapeutic Product Effect Incomplete 93 1.2 1.2 no signal
729 Drug Administered At Inappropriate Site 14 1.2 1.2 no signal
730 Conjunctivitis 24 1.2 1.2 no signal
731 Pain In Jaw 37 1.2 1.2 no signal
732 Wrong Technique In Drug Usage Process 48 1.2 1.2 no signal
733 Haematocrit Decreased 26 1.2 1.2 no signal
734 Head Injury 41 1.2 1.2 no signal
735 Speech Disorder 68 1.2 1.2 no signal
736 Diarrhoea 834 1.2 1.2 no signal
737 Expired Product Administered 43 1.2 1.2 no signal
738 Injection Site Bruising 102 1.2 1.2 no signal
739 Appendicitis 12 1.2 1.2 no signal
740 Road Traffic Accident 54 1.2 1.2 no signal
741 Injection Site Pain 389 1.2 1.2 no signal
742 Lymphopenia 18 1.2 1.2 no signal
743 Colitis Ulcerative 57 1.2 1.2 no signal
744 Muscle Atrophy 16 1.2 1.2 no signal
745 Peripheral Swelling 195 1.2 1.2 no signal
746 Movement Disorder 41 1.2 1.2 no signal
747 Body Temperature Increased 26 1.2 1.2 no signal
748 Productive Cough 60 1.2 1.2 no signal
749 Rib Fracture 26 1.2 1.2 no signal
750 Sedation 33 1.2 1.2 no signal
751 Oedema Peripheral 154 1.2 1.2 no signal
752 Needle Issue 36 1.2 1.2 no signal
753 Bronchospasm 18 1.2 1.2 no signal
754 Feeding Disorder 25 1.2 1.2 no signal
755 Impaired Healing 41 1.2 1.2 no signal
756 Taste Disorder 25 1.2 1.2 no signal
757 Activities Of Daily Living Impaired 25 1.1 1.1 no signal
758 Therapy Change 12 1.1 1.1 no signal
759 Exposure Via Skin Contact 28 1.1 1.1 no signal
760 Anaphylactic Reaction 68 1.1 1.1 no signal
761 Neuropathy Peripheral 117 1.1 1.1 no signal
762 Atelectasis 12 1.1 1.1 no signal
763 Mouth Ulceration 26 1.1 1.1 no signal
764 Device Defective 20 1.1 1.1 no signal
765 Disorientation 49 1.1 1.1 no signal
766 Vomiting 575 1.1 1.1 no signal
767 Jaundice 33 1.1 1.1 no signal
768 Dysarthria 46 1.1 1.1 no signal
769 Oxygen Saturation Decreased 68 1.1 1.1 no signal
770 Pharyngeal Oedema 19 1.1 1.1 no signal
771 Secretion Discharge 15 1.1 1.1 no signal
772 Dyskinesia 49 1.1 1.1 no signal
773 Dyspnoea 682 1.1 1.1 no signal
774 Abnormal Behaviour 48 1.1 1.1 no signal
775 Asthenia 452 1.1 1.1 no signal
776 Musculoskeletal Disorder 23 1.1 1.1 no signal
777 Intestinal Obstruction 45 1.1 1.1 no signal
778 Clostridium Difficile Infection 26 1.1 1.1 no signal
779 Sinus Tachycardia 17 1.1 1.1 no signal
780 Retinal Detachment 11 1.1 1.1 no signal
781 Malignant Melanoma 16 1.1 1.1 no signal
782 Abscess 19 1.1 1.1 no signal
783 Eye Disorder 39 1.1 1.1 no signal
784 Visual Impairment 146 1.1 1.1 no signal
785 Arthropathy 66 1.1 1.1 no signal
786 Loss Of Consciousness 151 1.1 1.1 no signal
787 Hypokinesia 17 1.1 1.1 no signal
788 Generalised Tonic-clonic Seizure 19 1.1 1.1 no signal
789 Ageusia 29 1.1 1.1 no signal
790 Mobility Decreased 83 1.1 1.1 no signal
791 Abasia 29 1.1 1.1 no signal
792 Gastric Ulcer 22 1.1 1.1 no signal
793 Device Use Issue 20 1.1 1.1 no signal
794 Blood Urine Present 22 1.1 1.1 no signal
795 Skin Discolouration 53 1.1 1.1 no signal
796 Laceration 11 1.1 1.1 no signal
797 Psychotic Disorder 34 1.1 1.1 no signal
798 Product Dispensing Error 25 1.1 1.1 no signal
799 Platelet Count Increased 15 1.1 1.1 no signal
800 Staphylococcal Infection 38 1.1 1.1 no signal
801 Pulmonary Hypertension 24 1.1 1.1 no signal
802 Unintended Pregnancy 12 1.1 1.1 no signal
803 Oedema 62 1.1 1.1 no signal
804 Mass 16 1.1 1.1 no signal
805 Dehydration 152 1.1 1.1 no signal
806 Tachycardia 101 1.0 1.0 no signal
807 Menstruation Irregular 30 1.0 1.0 no signal
808 Clostridium Difficile Colitis 12 1.0 1.0 no signal
809 Therapy Partial Responder 17 1.0 1.0 no signal
810 Femur Fracture 35 1.0 1.0 no signal
811 Fall 373 1.0 1.0 no signal
812 Transient Ischaemic Attack 38 1.0 1.0 no signal
813 Injury 79 1.0 1.0 no signal
814 Vasculitis 13 1.0 1.0 no signal
815 Multiple Sclerosis Relapse 77 1.0 1.0 no signal
816 Proteinuria 21 1.0 1.0 no signal
817 Spinal Pain 13 1.0 1.0 no signal
818 Lower Respiratory Tract Infection 50 1.0 1.0 no signal
819 Prescribed Underdose 22 1.0 1.0 no signal
820 Incorrect Dose Administered 248 1.0 1.0 no signal
821 Agitation 81 1.0 1.0 no signal
822 Drug Dispensing Error 17 1.0 1.0 no signal
823 Acute Respiratory Failure 21 1.0 1.0 no signal
824 Covid-19 Pneumonia 13 1.0 1.0 no signal
825 White Blood Cell Count Increased 42 1.0 1.0 no signal
826 Blister 61 1.0 1.0 no signal
827 Bone Disorder 20 1.0 1.0 no signal
828 Psychomotor Hyperactivity 18 1.0 1.0 no signal
829 Acne 82 1.0 1.0 no signal
830 Drug Level Decreased 11 1.0 1.0 no signal
831 Dry Skin 141 1.0 1.0 no signal
832 Seizure 123 1.0 1.0 no signal
833 Haematochezia 59 1.0 1.0 no signal
834 Skin Burning Sensation 76 1.0 1.0 no signal
835 Angioedema 47 1.0 1.0 no signal
836 Immune System Disorder 14 1.0 1.0 no signal
837 Hepatic Cytolysis 13 1.0 1.0 no signal
838 Blood Calcium Decreased 12 1.0 1.0 no signal
839 Osteomyelitis 19 1.0 1.0 no signal
840 Lower Limb Fracture 20 1.0 1.0 no signal
841 Tooth Extraction 13 1.0 1.0 no signal
842 Device Issue 91 1.0 1.0 no signal
843 Inappropriate Schedule Of Drug Administration 75 1.0 1.0 no signal
844 Hernia 20 1.0 1.0 no signal
845 Pleural Effusion 63 1.0 1.0 no signal
846 Respiratory Disorder 31 1.0 1.0 no signal
847 Liver Function Test Increased 22 1.0 1.0 no signal
848 Pancreatitis Acute 23 1.0 1.0 no signal
849 Syncope 103 0.9 0.9 no signal
850 Product Dose Omission 68 0.9 0.9 no signal
851 Underdose 75 0.9 0.9 no signal
852 Therapeutic Response Decreased 61 0.9 0.9 no signal
853 Blood Pressure Abnormal 20 0.9 0.9 no signal
854 Therapy Non-responder 45 0.9 0.9 no signal
855 Medication Error 56 0.9 0.9 no signal
856 Ulcer 16 0.9 0.9 no signal
857 Pruritus Generalised 22 0.9 0.9 no signal
858 Haematoma 26 0.9 0.9 no signal
859 Gait Inability 33 0.9 0.9 no signal
860 Drug Administration Error 31 0.9 0.9 no signal
861 Skin Exfoliation 82 0.9 0.9 no signal
862 No Adverse Event 175 0.9 0.9 no signal
863 Mental Disorder 43 0.9 0.9 no signal
864 Complication Associated With Device 13 0.9 0.9 no signal
865 Epilepsy 30 0.9 0.9 no signal
866 Chronic Kidney Disease 75 0.9 0.9 no signal
867 Incorrect Product Storage 13 0.9 0.9 no signal
868 Skin Ulcer 25 0.9 0.9 no signal
869 Blood Sodium Decreased 18 0.9 0.9 no signal
870 Visual Acuity Reduced 32 0.9 0.9 no signal
871 Thrombosis 77 0.9 0.9 no signal
872 Hallucination, Visual 20 0.9 0.9 no signal
873 Rash Generalised 25 0.9 0.9 no signal
874 Spinal Disorder 9 0.9 0.9 no signal
875 Product Storage Error 82 0.9 0.9 no signal
876 Incorrect Drug Administration Duration 27 0.9 0.9 no signal
877 Arrhythmia 45 0.9 0.9 no signal
878 Hypophagia 24 0.9 0.9 no signal
879 Decreased Appetite 219 0.9 0.9 no signal
880 Face Oedema 16 0.9 0.9 no signal
881 Intentional Self-injury 19 0.9 0.9 no signal
882 Injection Site Haemorrhage 74 0.9 0.9 no signal
883 Skin Cancer 20 0.9 0.9 no signal
884 Blood Bilirubin Increased 25 0.9 0.9 no signal
885 Muscle Rigidity 11 0.8 0.8 no signal
886 Gastric Disorder 32 0.8 0.8 no signal
887 Pharmaceutical Product Complaint 24 0.8 0.8 no signal
888 Tooth Loss 19 0.8 0.8 no signal
889 Hyperglycaemia 33 0.8 0.8 no signal
890 Confusional State 147 0.8 0.8 no signal
891 Glomerular Filtration Rate Decreased 11 0.8 0.8 no signal
892 Hypoacusis 39 0.8 0.8 no signal
893 Anhedonia 24 0.8 0.8 no signal
894 Adverse Drug Reaction 81 0.8 0.8 no signal
895 Treatment Noncompliance 49 0.8 0.8 no signal
896 Malnutrition 10 0.8 0.8 no signal
897 Lung Disorder 44 0.8 0.8 no signal
898 Small Intestinal Obstruction 11 0.8 0.8 no signal
899 Skin Irritation 41 0.8 0.8 no signal
900 Blood Pressure Decreased 59 0.8 0.8 no signal
901 Drug Dose Omission 149 0.8 0.8 no signal
902 Cyanosis 14 0.8 0.8 no signal
903 Laboratory Test Abnormal 26 0.8 0.8 no signal
904 Skin Lesion 24 0.8 0.8 no signal
905 Akathisia 12 0.8 0.8 no signal
906 Deafness 23 0.8 0.8 no signal
907 Circulatory Collapse 15 0.8 0.8 no signal
908 Folliculitis 9 0.8 0.8 no signal
909 Neoplasm 10 0.8 0.8 no signal
910 Incorrect Dose Administered By Device 22 0.8 0.8 no signal
911 Hypotension 172 0.8 0.8 no signal
912 Device Failure 13 0.8 0.8 no signal
913 Neoplasm Progression 30 0.8 0.8 no signal
914 C-reactive Protein Increased 31 0.8 0.8 no signal
915 Blindness Unilateral 12 0.8 0.8 no signal
916 Breast Cancer Stage I 8 0.8 0.8 no signal
917 Colitis 32 0.8 0.8 no signal
918 Urinary Retention 28 0.8 0.8 no signal
919 Pulmonary Fibrosis 16 0.8 0.8 no signal
920 Serotonin Syndrome 16 0.8 0.8 no signal
921 Emotional Distress 100 0.8 0.8 no signal
922 Eye Haemorrhage 11 0.8 0.8 no signal
923 Ill-defined Disorder 50 0.8 0.8 no signal
924 Cardiac Failure 66 0.8 0.8 no signal
925 Hallucination, Auditory 13 0.8 0.8 no signal
926 Uveitis 11 0.8 0.8 no signal
927 Adverse Event 75 0.8 0.7 no signal
928 Hallucination 61 0.8 0.7 no signal
929 Rectal Haemorrhage 35 0.7 0.7 no signal
930 Wheezing 48 0.7 0.7 no signal
931 Transaminases Increased 18 0.7 0.7 no signal
932 Hepatomegaly 8 0.7 0.7 no signal
933 Obstructive Airways Disorder 9 0.7 0.7 no signal
934 Hypoglycaemia 39 0.7 0.7 no signal
935 Spinal Fracture 16 0.7 0.7 no signal
936 Extra Dose Administered 32 0.7 0.7 no signal
937 Intentional Drug Misuse 17 0.7 0.7 no signal
938 Eosinophilia 14 0.7 0.7 no signal
939 Dyspnoea Exertional 30 0.7 0.7 no signal
940 Hypoxia 28 0.7 0.7 no signal
941 Nervous System Disorder 25 0.7 0.7 no signal
942 Renal Disorder 37 0.7 0.7 no signal
943 Motor Dysfunction 8 0.7 0.7 no signal
944 Bone Loss 12 0.7 0.7 no signal
945 Drug Effective For Unapproved Indication 23 0.7 0.7 no signal
946 Cholestasis 15 0.7 0.7 no signal
947 Localised Infection 19 0.7 0.7 no signal
948 Faeces Discoloured 17 0.7 0.7 no signal
949 Electrolyte Imbalance 9 0.7 0.7 no signal
950 Glaucoma 15 0.7 0.7 no signal
951 Scratch 8 0.7 0.7 no signal
952 Aspartate Aminotransferase Increased 41 0.7 0.7 no signal
953 Post Procedural Haemorrhage 9 0.7 0.7 no signal
954 Sexual Dysfunction 9 0.7 0.7 no signal
955 Ejection Fraction Decreased 12 0.7 0.7 no signal
956 Menstruation Delayed 8 0.7 0.7 no signal
957 Pallor 21 0.7 0.7 no signal
958 Type 2 Diabetes Mellitus 26 0.7 0.7 no signal
959 Anorexia 10 0.7 0.7 no signal
960 Bone Density Decreased 24 0.7 0.7 no signal
961 Ataxia 9 0.7 0.7 no signal
962 Therapy Interrupted 52 0.7 0.7 no signal
963 Tubulointerstitial Nephritis 14 0.7 0.7 no signal
964 Thyroid Cancer 9 0.7 0.7 no signal
965 Arteriosclerosis 7 0.7 0.7 no signal
966 Systemic Lupus Erythematosus 26 0.7 0.7 no signal
967 Diabetes Mellitus Inadequate Control 13 0.7 0.7 no signal
968 Pulmonary Thrombosis 8 0.7 0.7 no signal
969 White Blood Cell Count Decreased 79 0.7 0.7 no signal
970 No Therapeutic Response 9 0.7 0.7 no signal
971 Ventricular Tachycardia 12 0.7 0.7 no signal
972 Pneumonia 234 0.7 0.7 no signal
973 Thrombotic Microangiopathy 7 0.7 0.7 no signal
974 Wound 20 0.7 0.7 no signal
975 Atrial Fibrillation 70 0.7 0.7 no signal
976 Alanine Aminotransferase Increased 44 0.7 0.7 no signal
977 Glossodynia 16 0.7 0.7 no signal
978 Circumstance Or Information Capable Of Leading To Medication Error 24 0.7 0.7 no signal
979 Brain Oedema 9 0.7 0.7 no signal
980 Fistula 8 0.7 0.7 no signal
981 Convulsion 41 0.7 0.7 no signal
982 Scab 8 0.7 0.7 no signal
983 Hepatitis 18 0.6 0.6 no signal
984 Anaemia 134 0.6 0.6 no signal
985 Intraocular Pressure Increased 9 0.6 0.6 no signal
986 Wrong Technique In Device Usage Process 32 0.6 0.6 no signal
987 Pancreatitis 37 0.6 0.6 no signal
988 Pericardial Effusion 16 0.6 0.6 no signal
989 Encephalopathy 17 0.6 0.6 no signal
990 Epistaxis 52 0.6 0.6 no signal
991 Stomatitis 42 0.6 0.6 no signal
992 Mental Status Changes 19 0.6 0.6 no signal
993 Liver Function Test Abnormal 20 0.6 0.6 no signal
994 Splenomegaly 8 0.6 0.6 no signal
995 Injection Site Haematoma 10 0.6 0.6 no signal
996 Accidental Exposure To Product 68 0.6 0.6 no signal
997 Pulmonary Congestion 9 0.6 0.6 no signal
998 Aggression 34 0.6 0.6 no signal
999 Suicide Attempt 41 0.6 0.6 no signal
1000 Accident 8 0.6 0.6 no signal
1001 Ischaemic Stroke 12 0.6 0.6 no signal
1002 Myoclonus 8 0.6 0.6 no signal
1003 Gout 12 0.6 0.6 no signal
1004 Pneumonitis 18 0.6 0.6 no signal
1005 Leukocytosis 12 0.6 0.6 no signal
1006 Blindness 27 0.6 0.6 no signal
1007 Pericarditis 11 0.6 0.6 no signal
1008 Diabetes Mellitus 50 0.6 0.6 no signal
1009 Brain Neoplasm 6 0.6 0.6 no signal
1010 Respiratory Distress 18 0.6 0.6 no signal
1011 End Stage Renal Disease 12 0.6 0.6 no signal
1012 Hypomagnesaemia 9 0.6 0.6 no signal
1013 Blood Glucose Abnormal 12 0.6 0.6 no signal
1014 Haematotoxicity 6 0.6 0.6 no signal
1015 Blood Alkaline Phosphatase Increased 16 0.6 0.6 no signal
1016 Injection Site Extravasation 8 0.6 0.6 no signal
1017 Nephropathy 6 0.6 0.6 no signal
1018 Hepatocellular Injury 9 0.6 0.6 no signal
1019 Rash Maculo-papular 14 0.6 0.6 no signal
1020 Metabolic Acidosis 20 0.6 0.6 no signal
1021 Haemoglobin Decreased 65 0.6 0.6 no signal
1022 Drug Withdrawal Syndrome 56 0.6 0.6 no signal
1023 Red Blood Cell Sedimentation Rate Increased 7 0.6 0.6 no signal
1024 Red Blood Cell Count Decreased 18 0.6 0.6 no signal
1025 Ventricular Fibrillation 7 0.6 0.6 no signal
1026 Blood Lactate Dehydrogenase Increased 10 0.6 0.6 no signal
1027 Oral Pain 14 0.6 0.6 no signal
1028 Device Dislocation 27 0.6 0.6 no signal
1029 Local Swelling 11 0.6 0.6 no signal
1030 Blood Potassium Increased 10 0.6 0.6 no signal
1031 Inability To Afford Medication 6 0.6 0.6 no signal
1032 Synovitis 11 0.6 0.6 no signal
1033 Depressed Level Of Consciousness 24 0.6 0.6 no signal
1034 Delirium 21 0.6 0.6 no signal
1035 Emphysema 6 0.5 0.5 no signal
1036 Device Leakage 25 0.5 0.5 no signal
1037 Macular Degeneration 7 0.5 0.5 no signal
1038 Drug Reaction With Eosinophilia And Systemic Symptoms 15 0.5 0.5 no signal
1039 Neutrophil Count Increased 6 0.5 0.5 no signal
1040 Bradycardia 31 0.5 0.5 no signal
1041 Device Related Infection 9 0.5 0.5 no signal
1042 Haematuria 20 0.5 0.5 no signal
1043 Hypocalcaemia 11 0.5 0.5 no signal
1044 Delusion 9 0.5 0.5 no signal
1045 Incorrect Route Of Drug Administration 21 0.5 0.5 no signal
1046 Schizophrenia 7 0.5 0.5 no signal
1047 Respiratory Failure 42 0.5 0.5 no signal
1048 Device Delivery System Issue 15 0.5 0.5 no signal
1049 Sepsis 64 0.5 0.5 no signal
1050 Lung Infection 9 0.5 0.5 no signal
1051 Cerebrovascular Accident 97 0.5 0.5 no signal
1052 Drug Effect Incomplete 21 0.5 0.5 no signal
1053 Pneumothorax 9 0.5 0.5 no signal
1054 Abnormal Weight Gain 7 0.5 0.5 no signal
1055 Haematemesis 14 0.5 0.5 no signal
1056 Device Malfunction 37 0.5 0.5 no signal
1057 Metastases To Bone 9 0.5 0.5 no signal
1058 Metastases To Central Nervous System 7 0.5 0.5 no signal
1059 Blood Glucose Fluctuation 6 0.5 0.5 no signal
1060 Grand Mal Convulsion 5 0.5 0.5 no signal
1061 Cerebral Infarction 13 0.5 0.5 no signal
1062 Leukaemia 5 0.5 0.5 no signal
1063 Hepatic Failure 16 0.5 0.5 no signal
1064 Rebound Effect 6 0.5 0.5 no signal
1065 Posterior Reversible Encephalopathy Syndrome 5 0.5 0.5 no signal
1066 Cardiac Disorder 49 0.5 0.5 no signal
1067 Product Complaint 13 0.5 0.5 no signal
1068 Angina Pectoris 15 0.5 0.5 no signal
1069 Metastases To Lung 6 0.5 0.5 no signal
1070 Blood Creatinine Increased 34 0.5 0.5 no signal
1071 Liver Disorder 23 0.5 0.5 no signal
1072 Blood Glucose Decreased 25 0.5 0.5 no signal
1073 Sinus Bradycardia 5 0.5 0.5 no signal
1074 Lymphoma 8 0.5 0.5 no signal
1075 Glycosylated Haemoglobin Increased 13 0.5 0.5 no signal
1076 Acute Hepatic Failure 7 0.5 0.5 no signal
1077 Cardiovascular Disorder 13 0.5 0.5 no signal
1078 Intentional Overdose 32 0.5 0.5 no signal
1079 Disseminated Intravascular Coagulation 7 0.5 0.5 no signal
1080 Helicobacter Infection 5 0.5 0.5 no signal
1081 Septic Shock 21 0.4 0.4 no signal
1082 Complication Of Device Insertion 9 0.4 0.4 no signal
1083 Device Difficult To Use 32 0.4 0.4 no signal
1084 Peritonitis 10 0.4 0.4 no signal
1085 Multiple Fractures 8 0.4 0.4 no signal
1086 Chronic Obstructive Pulmonary Disease 25 0.4 0.4 no signal
1087 Fracture 9 0.4 0.4 no signal
1088 Full Blood Count Abnormal 5 0.4 0.4 no signal
1089 Neutrophil Count Decreased 19 0.4 0.4 no signal
1090 Accidental Overdose 17 0.4 0.4 no signal
1091 Hand Deformity 6 0.4 0.4 no signal
1092 Blood Count Abnormal 7 0.4 0.4 no signal
1093 Drug Eruption 8 0.4 0.4 no signal
1094 Hospitalisation 69 0.4 0.4 no signal
1095 Full Blood Count Decreased 9 0.4 0.4 no signal
1096 Myocarditis 5 0.4 0.4 no signal
1097 Platelet Count Decreased 47 0.4 0.4 no signal
1098 Acute Myocardial Infarction 13 0.4 0.4 no signal
1099 Gingival Bleeding 6 0.4 0.4 no signal
1100 Hip Fracture 14 0.4 0.4 no signal
1101 Coronary Artery Occlusion 6 0.4 0.4 no signal
1102 Renal Injury 13 0.4 0.4 no signal
1103 General Physical Health Deterioration 49 0.4 0.4 no signal
1104 Coronary Artery Disease 13 0.4 0.4 no signal
1105 Renal Failure Acute 18 0.4 0.4 no signal
1106 Altered State Of Consciousness 9 0.4 0.4 no signal
1107 Myelodysplastic Syndrome 6 0.4 0.4 no signal
1108 Device Expulsion 27 0.4 0.4 no signal
1109 Pulmonary Arterial Hypertension 6 0.4 0.4 no signal
1110 Renal Failure 55 0.4 0.4 no signal
1111 Dystonia 8 0.4 0.4 no signal
1112 Respiratory Depression 5 0.4 0.4 no signal
1113 Febrile Neutropenia 27 0.4 0.4 no signal
1114 Blood Glucose Increased 77 0.4 0.4 no signal
1115 Hospice Care 4 0.4 0.4 no signal
1116 Acute Kidney Injury 61 0.4 0.4 no signal
1117 Pneumocystis Jirovecii Pneumonia 4 0.4 0.4 no signal
1118 Syringe Issue 7 0.4 0.4 no signal
1119 Toxic Skin Eruption 4 0.4 0.4 no signal
1120 Cardiac Failure Congestive 32 0.4 0.4 no signal
1121 Hypothermia 4 0.4 0.4 no signal
1122 Osteonecrosis 13 0.4 0.4 no signal
1123 Cerebral Haemorrhage 14 0.4 0.4 no signal
1124 Electrocardiogram Qt Prolonged 14 0.4 0.4 no signal
1125 Device Mechanical Issue 5 0.4 0.4 no signal
1126 Skeletal Injury 4 0.4 0.4 no signal
1127 Myelosuppression 13 0.4 0.4 no signal
1128 Transfusion 4 0.4 0.4 no signal
1129 Pancytopenia 21 0.3 0.3 no signal
1130 Drug Toxicity 5 0.3 0.3 no signal
1131 Device Occlusion 5 0.3 0.3 no signal
1132 Myocardial Infarction 62 0.3 0.3 no signal
1133 Drug Dose Omission By Device 27 0.3 0.3 no signal
1134 Tardive Dyskinesia 10 0.3 0.3 no signal
1135 Disease Progression 41 0.3 0.3 no signal
1136 Gastric Haemorrhage 4 0.3 0.3 no signal
1137 Plasma Cell Myeloma 13 0.3 0.3 no signal
1138 Pemphigus 4 0.3 0.3 no signal
1139 Poisoning 4 0.3 0.3 no signal
1140 Inflammatory Bowel Disease 3 0.3 0.3 no signal
1141 Injury Associated With Device 6 0.3 0.3 no signal
1142 Neutropenia 40 0.3 0.3 no signal
1143 Device Use Error 10 0.3 0.3 no signal
1144 Toxicity To Various Agents 48 0.3 0.3 no signal
1145 Lung Neoplasm Malignant 11 0.2 0.2 no signal
1146 Renal Impairment 21 0.2 0.2 no signal
1147 Device Deployment Issue 3 0.2 0.2 no signal
1148 Cytomegalovirus Infection 4 0.2 0.2 no signal
1149 Neoplasm Malignant 16 0.2 0.2 no signal
1150 Tuberculosis 3 0.2 0.2 no signal
1151 Diabetic Ketoacidosis 5 0.2 0.2 no signal
1152 Hepatic Cancer 5 0.2 0.2 no signal
1153 Osteonecrosis Of Jaw 5 0.2 0.2 no signal
1154 Drug Withdrawal Syndrome Neonatal 3 0.2 0.2 no signal
1155 Drug Abuse 16 0.2 0.2 no signal
1156 Completed Suicide 16 0.2 0.2 no signal
1157 Cardiac Arrest 15 0.2 0.2 no signal
1158 Gastrointestinal Haemorrhage 15 0.2 0.2 no signal
1159 Malignant Neoplasm Progression 18 0.2 0.2 no signal
1160 Pancreatic Carcinoma 5 0.2 0.2 no signal
1161 Extrapyramidal Disorder 4 0.1 0.1 no signal
1162 Death 100 0.1 0.1 no signal
1163 Drug Dependence 18 0.1 0.1 no signal
1164 Colorectal Cancer 5 0.1 0.1 no signal
1165 Dependence 3 0.0 0.0 no signal