Reaction

Heart Valve Replacement reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,447 reports · 21 co-occurring drugs

As of the last recalculation, Heart Valve Replacement appears in 1,447 FAERS reports alongside 21 co-occurring drug terms. The strongest observed disproportionality signal is RANOLAZINE (PRR 23.7).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
DrugCo-reportsPRRROR
Ranolazine1723.723.7
Bosentan4312.612.6
Tafamidis1012.312.3
Ambrisentan8210.010.0
Epoprostenol99.910.0
Dronedarone79.99.9
Macitentan408.58.5
Selexipag158.48.4
Umeclidinium Bromide And Vilanterol Trifenatate97.87.8
Patiromer77.37.3
Vibegron47.27.2
Ibrutinib366.56.6
Risankizumab-Rzaa366.56.5
Carbidopa And Levodopa195.85.8
Nintedanib125.55.5
Relugolix74.34.3
Dabigatran Etexilate Mesylate214.24.2
Methoxy Polyethylene Glycol-Epoetin Beta33.93.9
Evolocumab383.43.4
Droxidopa32.02.0
Cinacalcet Hydrochloride51.51.5

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.