Reaction
Oesophageal Perforation reporting signals
As of the last recalculation, Oesophageal Perforation appears in 821 FAERS reports alongside 18 co-occurring drug terms. The strongest observed disproportionality signal is EPLERENONE (PRR 70.2).
Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.
| Drug | Co-reports | PRR | ROR |
|---|---|---|---|
| Eplerenone | 34 | 70.2 | 70.4 |
| Dextrose | 31 | 62.0 | 62.1 |
| Cefuroxime | 27 | 61.9 | 62.0 |
| Dextrose Monohydrate | 31 | 61.1 | 61.2 |
| Sennosides 8.6 Mg Tablets | 32 | 40.2 | 40.3 |
| Bleomycin Sulfate | 16 | 40.0 | 40.1 |
| Senna | 32 | 40.0 | 40.1 |
| Senna Leaf | 34 | 38.9 | 39.0 |
| Clarithromycin | 37 | 28.6 | 28.6 |
| Sennosides | 32 | 28.2 | 28.2 |
| Cisplatin | 67 | 23.6 | 23.6 |
| Lenvatinib | 22 | 17.4 | 17.5 |
| Fluorouracil Cream, 0.5% | 38 | 13.2 | 13.2 |
| Pemetrexed | 11 | 13.2 | 13.2 |
| Fluorouracil | 38 | 13.0 | 13.0 |
| Docetaxel Anhydrous | 23 | 8.9 | 8.9 |
| Docetaxel | 23 | 8.9 | 8.9 |
| Durvalumab | 5 | 6.3 | 6.3 |