Data 21 October 2026 Compiled by an agent pipeline, verified quote-by-quote Methods · Changelog · Corrections

Open Source Medicine Foundation

Disease risks and vaccine efficacy

Compiled October 2026

Vaccine Data Navigator documents what vaccines can cause. This companion documents the other side: what the diseases do, including after the acute illness, and how well each vaccine prevents them, for whom. 2156 sourced estimates, each quoted verbatim from its source and annotated by population, intervention, comparator, outcome and study design.

By country

How many people are vaccinated, and how much disease is reported, where you live: WHO/UNICEF coverage estimates beside each country's own figure, reported cases, and the national schedule, with a data-quality grade on every series.

Vaccination rates and disease by country →   Compare countries by disease   How grades work

BCG vaccine

Tuberculosis (all forms), Tuberculous meningitis and miliary tuberculosis in children

29 risk · 10 post-acute · 32 efficacy · 2 safety

COVID-19 vaccines

COVID-19 (acute), Post-acute sequelae of SARS-CoV-2 infection (long COVID, MIS-C, post-infection cardiovascular events)

13 risk · 11 post-acute · 37 efficacy · 2 safety

DTaP / Tdap (diphtheria, tetanus, pertussis)

Pertussis (whooping cough), Diphtheria, Tetanus

49 risk · 2 post-acute · 76 efficacy · 2 safety

Hepatitis A vaccine

Hepatitis A

39 risk · 1 post-acute · 39 efficacy · 0 safety

Hepatitis B vaccine

Acute hepatitis B, Chronic hepatitis B infection, Cirrhosis and hepatocellular carcinoma after chronic hepatitis B

33 risk · 11 post-acute · 69 efficacy · 0 safety

Hib (Haemophilus influenzae type b) vaccine

Invasive Haemophilus influenzae type b disease (meningitis, pneumonia, epiglottitis, bacteraemia), Sequelae of Hib meningitis (hearing loss, neurodisability)

36 risk · 11 post-acute · 45 efficacy · 2 safety

HPV vaccines (2v, 4v, 9v)

Genital HPV infection (prevalence, persistent infection), Cervical precancer (CIN2+/CIN3+, AIS), Cervical cancer, Other HPV-attributable cancers (anal, oropharyngeal, vulvar, vaginal, penile) and genital warts / papillomatosis

23 risk · 10 post-acute · 90 efficacy · 5 safety

Influenza (seasonal) vaccines

Seasonal influenza (including the 2009 A(H1N1)pdm09 pandemic), Post-influenza cardiovascular events (myocardial infarction, stroke)

37 risk · 9 post-acute · 105 efficacy · 0 safety

Japanese encephalitis vaccines (Ixiaro, SA 14-14-2, Imojev)

Japanese encephalitis, Neurological, cognitive and psychiatric sequelae after Japanese encephalitis

29 risk · 11 post-acute · 32 efficacy · 2 safety

Meningococcal vaccines (MenACWY, MenB, MenC, MenA conjugate)

Invasive meningococcal disease (meningitis and septicaemia), Sequelae of invasive meningococcal disease (hearing loss, amputation, neurological and psychological deficits)

39 risk · 14 post-acute · 53 efficacy · 0 safety

MMR (measles, mumps, rubella)

Measles, Mumps, Rubella, Chickenpox (varicella)

7 risk · 2 post-acute · 17 efficacy · 5 safety

Oral cholera vaccines (Shanchol, Euvichol, Dukoral, Vaxchora)

Cholera

29 risk · 0 post-acute · 96 efficacy · 0 safety

Pneumococcal conjugate vaccines (PCV7/10/13/15/20) and PPSV23

Invasive pneumococcal disease (bacteraemia, meningitis, bacteraemic pneumonia), Pneumococcal pneumonia (community-acquired, non-invasive), Sequelae after pneumococcal meningitis (hearing loss, neurological disability)

38 risk · 8 post-acute · 74 efficacy · 1 safety

Polio vaccines (IPV, OPV)

Poliomyelitis, Post-polio syndrome

50 risk · 10 post-acute · 59 efficacy · 12 safety

Rabies vaccines (pre- and post-exposure prophylaxis)

Rabies

30 risk · 1 post-acute · 45 efficacy · 3 safety

Rotavirus vaccines (RotaTeq, Rotarix, Rotavac, Rotasiil)

Rotavirus gastroenteritis

30 risk · 0 post-acute · 88 efficacy · 13 safety

RSV vaccines (Arexvy RSVPreF3 OA, Abrysvo RSVpreF, mResvia mRNA-1345), maternal RSVpreF, and nirsevimab (monoclonal antibody)

RSV lower respiratory tract infection in infants and young children, RSV disease in older adults, Recurrent wheeze and asthma after infant RSV infection

35 risk · 8 post-acute · 55 efficacy · 5 safety

Shingles (herpes zoster) vaccines

Herpes zoster (shingles), Post-herpetic neuralgia, Stroke and myocardial infarction after herpes zoster

28 risk · 18 post-acute · 56 efficacy · 3 safety

Typhoid vaccines (TCV Typbar, Vi polysaccharide, Ty21a)

Typhoid fever

44 risk · 4 post-acute · 68 efficacy · 3 safety

Varicella (chickenpox) vaccine

Chickenpox (varicella), Congenital varicella syndrome and neonatal varicella, Herpes zoster after wild-type varicella infection

37 risk · 11 post-acute · 59 efficacy · 2 safety

Yellow fever vaccine (17D)

Yellow fever

26 risk · 0 post-acute · 48 efficacy · 18 safety

Every figure here is quoted verbatim from the source named in its row, and is shown on the scale the source uses. Nothing is recomputed or combined. Open “quote” on any row to check it against the cached source.

Cite this page. Disease risks and vaccine efficacy. Open Source Medicine Foundation. Estimates compiled 21 October 2026 from the sources named in each row. https://vaccinedatanavigator.org/disease-risk/

BibTeX
@misc{vaccinedatanavigator-disease-risk-2026,
  title        = {Disease risks and vaccine efficacy},
  author       = {{Open Source Medicine Foundation}},
  year         = {2026},
  note         = {Disease risk and vaccine efficacy estimates, compiled 21 October 2026; every value quoted verbatim from its source.},
  howpublished = {\url{https://vaccinedatanavigator.org/disease-risk/}}
}

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