Furosemide vs Torsemide: side effects in FDA adverse event reports
At a glance
| Furosemide | Torsemide | |
|---|---|---|
| Drug class | Loop Diuretic | Loop Diuretic |
| Brand names | – | – |
| FAERS reports | 398,182 | 32,883 |
| Serious | 81% | 81% |
| Death outcome | 61,850 | 4,435 |
| Boxed warning | No | No |
Signals both drugs share
| Reaction | Furosemide | Torsemide | Label screen (A / B) |
|---|---|---|---|
| Cardiac failure chronic | 996 · PRR 15.8 | 199 · PRR 31.2 | Not in label — unassessed / Labeled (related wording) |
| Nephrogenic anaemia | 1,661 · PRR 28.7 | 198 · PRR 28.1 | Likely indication confounding / Not in label — unassessed |
| Hyperparathyroidism secondary | 895 · PRR 28.4 | 149 · PRR 39.8 | Not in label — unassessed / Not in label — unassessed |
| Hypervolaemia | 656 · PRR 8.2 | 177 · PRR 24.4 | Not in label — unassessed / Not in label — unassessed |
| Chronic kidney disease-mineral and bone disorder | 367 · PRR 26.9 | 51 · PRR 31.6 | Not in label — unassessed / Not in label — unassessed |
Labeled signals distinctive to Furosemide
- End stage renal disease — n=3,380, PRR 11.6 Labeled (related wording)
- Orthostatic hypotension — n=2,320, PRR 7.9 Labeled adverse reaction
- Metabolic alkalosis — n=428, PRR 19.0 Labeled (related wording)
Labeled signals distinctive to Torsemide
- None stood out among the strongest labeled signals.
Common questions
Which has more reported side effects, Furosemide or Torsemide?
Furosemide has 398,182 FAERS reports and Torsemide 32,883. More reports does not mean more dangerous: volume follows how widely and how long a drug has been used, prescription vs over-the-counter status, and publicity. The seriousness share (81% vs 81%) is a better like-for-like signal of the kind of problems reported.
Which side effects do Furosemide and Torsemide share?
Both drugs carry disproportionality signals for cardiac failure chronic, nephrogenic anaemia, hyperparathyroidism secondary, hypervolaemia, chronic kidney disease-mineral and bone disorder. Shared signals often reflect a shared drug class or the condition both are used for.
Is Furosemide or Torsemide safer?
FAERS cannot answer that: it has no denominator and no comparator. Use this page to see which risks are already on each label and which signals are unlabeled, then check the prescribing information and your clinician for your situation.
Sources: openFDA FAERS pair statistics (OpenPV build 2026-09-14), FDA labels via openFDA, openFDA count queries for seriousness and deaths. Pair chosen because it is a commonly searched comparison. Generated 2026-10-08.