OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Alirocumab

1,032 flagged reaction(s) · 67,106 total co-reports · max PRR 2,186.8
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Fractional Exhaled Nitric Oxide Increased 124 2,186.8 2,197.7 signal
2 Skin Pressure Mark 84 696.2 698.6 signal
3 Urticaria Contact 9 276.3 276.4 signal
4 Administration Site Indentation 12 221.0 221.1 signal
5 Product Delivery Mechanism Issue 542 105.5 107.8 signal
6 Myoglobin Blood Increased 127 75.9 76.3 signal
7 Low Density Lipoprotein Decreased 115 74.2 74.5 signal
8 Obstructive Sleep Apnoea Syndrome 110 71.9 72.2 signal
9 Application Site Injury 14 67.9 67.9 signal
10 Low Density Lipoprotein Abnormal 34 49.2 49.2 signal
11 Administration Site Wound 5 45.5 45.6 signal
12 Administration Site Bruise 17 44.6 44.6 signal
13 Low Density Lipoprotein Increased 356 40.8 41.3 signal
14 Blood Cholesterol Decreased 82 38.7 38.8 signal
15 Injection Site Indentation 84 36.1 36.2 signal
16 Brain Natriuretic Peptide Increased 127 36.1 36.3 signal
17 Plantar Fasciitis 132 34.3 34.5 signal
18 Morphoea 16 29.2 29.2 signal
19 Wrong Schedule 31 28.4 28.4 signal
20 Device Operational Issue 137 28.2 28.3 signal
21 Lipoprotein (a) Increased 9 26.3 26.3 signal
22 Device Use Issue 472 23.5 24.0 signal
23 Type Iia Hyperlipidaemia 6 22.8 22.8 signal
24 High Density Lipoprotein Increased 23 20.1 20.1 signal
25 Blood Triglycerides Decreased 7 17.7 17.7 signal
26 Product Dose Omission 1,364 17.7 18.6 signal
27 Product Preparation Error 416 17.2 17.5 signal
28 Injection Site Exfoliation 12 15.5 15.5 signal
29 Injection Site Hypoaesthesia 25 15.2 15.2 signal
30 Waist Circumference Increased 18 14.7 14.7 signal
31 Injury Associated With Device 335 14.2 14.4 signal
32 Injection Site Dryness 14 13.5 13.5 signal
33 Sensation Of Foreign Body 128 13.0 13.1 signal
34 Product Administered At Inappropriate Site 268 12.6 12.7 signal
35 High Density Lipoprotein Decreased 46 11.7 11.8 signal
36 Exostosis 112 10.4 10.5 signal
37 Increased Upper Airway Secretion 63 10.3 10.4 signal
38 Secretion Discharge 148 10.2 10.2 signal
39 Obstructive Airways Disorder 128 9.7 9.8 signal
40 Cardiac Pacemaker Replacement 5 9.3 9.3 signal
41 Injection Site Bruising 861 9.3 9.6 signal
42 Obstructive Pancreatitis 8 9.2 9.3 signal
43 Necrotising Myositis 9 8.8 8.8 signal
44 Induration 18 8.6 8.6 signal
45 Myalgia 1,683 8.4 8.9 signal
46 Influenza Like Illness 805 8.3 8.5 signal
47 Administration Site Pain 11 8.2 8.2 signal
48 Aortic Valve Replacement 12 8.2 8.2 signal
49 Injection Site Discolouration 120 8.2 8.2 signal
50 Foreign Body In Throat 28 7.8 7.8 signal
51 Muscle Discomfort 7 7.7 7.7 signal
52 Device Issue 789 7.7 7.9 signal
53 Injection Site Haemorrhage 694 7.4 7.6 signal
54 Injection Site Extravasation 108 7.3 7.4 signal
55 Peripheral Artery Occlusion 12 7.3 7.3 signal
56 Injection Site Rash 258 7.2 7.3 signal
57 Lipids Abnormal 6 7.1 7.1 signal
58 Stent Placement 67 7.0 7.1 signal
59 Pulmonary Sepsis 12 7.0 7.0 signal
60 Rhinorrhoea 534 7.0 7.1 signal
61 Injection Site Mass 302 6.9 7.0 signal
62 Hypergammaglobulinaemia Benign Monoclonal 5 6.9 6.9 signal
63 Blood Triglycerides Increased 144 6.9 6.9 signal
64 Injection Site Hypersensitivity 24 6.6 6.6 signal
65 Muscle Fatigue 33 6.6 6.6 signal
66 Product Preparation Issue 45 6.5 6.5 signal
67 Gingival Discomfort 5 6.5 6.5 signal
68 Vascular Graft 22 6.4 6.5 signal
69 Lipids Increased 15 6.3 6.3 signal
70 Pancreatitis Relapsing 6 6.3 6.3 signal
71 Injection Site Scab 7 6.2 6.2 signal
72 Eosinophilia 127 6.2 6.2 signal
73 Vascular Occlusion 15 6.0 6.0 signal
74 Blood Cholesterol Increased 326 5.9 6.0 signal
75 Urge Incontinence 6 5.9 5.9 signal
76 Renal Tubular Injury 8 5.8 5.8 signal
77 Pneumothorax 109 5.8 5.8 signal
78 Blood Triglycerides Abnormal 6 5.8 5.8 signal
79 Injection Site Discharge 34 5.6 5.6 signal
80 Drug Delivery System Malfunction 33 5.5 5.5 signal
81 Blood Cholesterol Abnormal 30 5.5 5.5 signal
82 Muscle Spasms 1,191 5.5 5.7 signal
83 Injection Site Swelling 482 5.4 5.5 signal
84 Injection Site Pruritus 422 5.4 5.4 signal
85 Injection Site Induration 80 5.2 5.2 signal
86 Cardiac Operation 52 5.2 5.2 signal
87 Angina Unstable 40 5.2 5.2 signal
88 Nasal Disorder 16 5.1 5.1 signal
89 Coronary Artery Disease 181 5.0 5.0 signal
90 Wrong Technique In Device Usage Process 268 5.0 5.0 signal
91 Injection Site Erythema 710 4.9 5.0 signal
92 Injection Site Warmth 118 4.8 4.9 signal
93 Spinal Stenosis 23 4.8 4.8 signal
94 Injection Related Reaction 9 4.7 4.7 signal
95 Injection Site Discomfort 56 4.6 4.6 signal
96 Muscle Disorder 44 4.6 4.6 signal
97 Cancer Surgery 5 4.4 4.4 signal
98 Sinus Pain 12 4.4 4.4 signal
99 Sinus Disorder 103 4.4 4.4 signal
100 Injection Site Inflammation 25 4.3 4.3 signal
101 Bladder Discomfort 6 4.1 4.1 signal
102 Arterial Occlusive Disease 38 4.1 4.1 signal
103 Catheterisation Cardiac 21 4.0 4.0 signal
104 Carotid Artery Disease 6 4.0 4.0 signal
105 Hypercholesterolaemia 45 4.0 4.0 signal
106 Congenital Central Nervous System Anomaly 5 3.9 3.9 signal
107 Blood Creatine Phosphokinase Increased 134 3.9 3.9 signal
108 Implantable Defibrillator Insertion 6 3.8 3.8 signal
109 Injection Site Injury 25 3.8 3.8 signal
110 Musculoskeletal Discomfort 78 3.8 3.8 signal
111 Hypersensitivity Pneumonitis 5 3.7 3.7 signal
112 Injection Site Urticaria 106 3.7 3.7 signal
113 Injection Site Pain 1,319 3.7 3.8 signal
114 Dyspnoea Exertional 163 3.7 3.7 signal
115 Paranasal Sinus Discomfort 16 3.6 3.6 signal
116 Vascular Injury 6 3.5 3.5 signal
117 Polymyalgia Rheumatica 13 3.5 3.5 signal
118 Injection Site Vesicles 25 3.5 3.5 signal
119 Product Storage Error 357 3.5 3.5 signal
120 Carotid Artery Occlusion 15 3.5 3.5 signal
121 Dysphonia 238 3.4 3.5 signal
122 Lack Of Injection Site Rotation 7 3.4 3.4 signal
123 Upper-airway Cough Syndrome 33 3.4 3.4 signal
124 Pruritus Generalised 88 3.4 3.4 signal
125 Angioplasty 6 3.4 3.4 signal
126 Viral Upper Respiratory Tract Infection 19 3.3 3.3 signal
127 Injection Site Scar 11 3.3 3.3 signal
128 Paranasal Sinus Hypersecretion 15 3.3 3.3 signal
129 Product Supply Issue 27 3.2 3.2 signal
130 Hepatitis E 6 3.2 3.2 signal
131 Sneezing 84 3.2 3.2 signal
132 Unevaluable Event 283 3.2 3.2 signal
133 Angiopathy 21 3.1 3.1 signal
134 Injection Site Reaction 255 3.1 3.2 signal
135 Musculoskeletal Pain 196 3.1 3.1 signal
136 Middle Ear Effusion 8 3.1 3.1 signal
137 Muscle Rupture 14 3.0 3.0 signal
138 Aneurysm 18 3.0 3.0 signal
139 Intentional Dose Omission 98 3.0 3.0 signal
140 Incorrect Dose Administered By Device 91 3.0 3.0 signal
141 Miliaria 6 3.0 3.0 signal
142 Injection Site Oedema 6 3.0 3.0 signal
143 Neck Surgery 8 2.9 2.9 signal
144 Infarction 24 2.9 2.9 signal
145 Sinus Congestion 47 2.9 2.9 signal
146 Nasal Congestion 203 2.9 2.9 signal
147 Drug Dose Omission By Device 265 2.9 2.9 signal
148 Hypersensitivity Vasculitis 9 2.9 2.9 signal
149 Device Defective 54 2.8 2.8 signal
150 Eye Operation 15 2.8 2.8 signal
151 Urinary Bladder Haemorrhage 7 2.8 2.8 signal
152 Drug Effect Less Than Expected 46 2.7 2.8 signal
153 Nasopharyngitis 599 2.7 2.8 signal
154 Throat Clearing 12 2.7 2.7 signal
155 Muscle Tightness 52 2.7 2.7 signal
156 Bronchospasm 46 2.7 2.7 signal
157 Oropharyngeal Pain 297 2.7 2.7 signal
158 Product Dose Omission Issue 913 2.7 2.8 signal
159 Pain In Extremity 942 2.7 2.8 signal
160 Sinus Headache 19 2.7 2.7 signal
161 Bladder Pain 10 2.7 2.7 signal
162 Peripheral Arterial Occlusive Disease 13 2.7 2.7 signal
163 Coronavirus Infection 21 2.7 2.7 signal
164 Glycosylated Haemoglobin Decreased 5 2.6 2.6 no signal
165 Coronary Artery Bypass 18 2.6 2.6 signal
166 Lipoma 8 2.6 2.6 signal
167 Aortic Valve Disease 5 2.6 2.6 no signal
168 Angina Pectoris 89 2.6 2.6 signal
169 Upper Respiratory Tract Congestion 9 2.6 2.6 signal
170 Urine Odour Abnormal 18 2.6 2.6 signal
171 Immune-mediated Myositis 8 2.6 2.6 signal
172 Oropharyngeal Discomfort 27 2.5 2.5 signal
173 Cardiac Pacemaker Insertion 18 2.5 2.5 signal
174 Cardiac Disorder 283 2.5 2.6 signal
175 Underdose 218 2.5 2.5 signal
176 Chest Discomfort 303 2.5 2.5 signal
177 Breast Swelling 8 2.5 2.5 signal
178 Dyslipidaemia 15 2.5 2.5 signal
179 Wheezing 172 2.4 2.5 signal
180 Varicose Vein 15 2.4 2.4 signal
181 Walking Disability 6 2.4 2.4 no signal
182 Respiratory Symptom 8 2.4 2.4 signal
183 Alopecia Areata 5 2.4 2.4 no signal
184 Muscular Weakness 322 2.4 2.4 signal
185 Pharyngeal Swelling 27 2.4 2.4 signal
186 Limb Discomfort 87 2.4 2.4 signal
187 Muscle Atrophy 35 2.3 2.3 signal
188 Tendon Pain 21 2.3 2.3 signal
189 Myopathy 24 2.3 2.3 signal
190 Coronary Arterial Stent Insertion 14 2.3 2.3 signal
191 Haemorrhage Urinary Tract 7 2.3 2.3 signal
192 Therapeutic Response Decreased 163 2.3 2.3 signal
193 Back Disorder 44 2.3 2.3 signal
194 Arteriosclerosis 25 2.2 2.2 signal
195 Influenza 295 2.2 2.2 signal
196 Intercepted Product Storage Error 9 2.2 2.2 signal
197 Coronary Artery Occlusion 36 2.2 2.2 signal
198 Injection Site Irritation 33 2.2 2.2 signal
199 Lichen Planus 6 2.2 2.2 no signal
200 Pigmentation Disorder 16 2.2 2.2 signal
201 Functional Gastrointestinal Disorder 9 2.2 2.2 signal
202 Discouragement 6 2.2 2.2 no signal
203 Arthralgia 1,074 2.2 2.2 signal
204 Cough 725 2.2 2.2 signal
205 Aortic Stenosis 9 2.2 2.2 signal
206 Glycosylated Haemoglobin Increased 65 2.2 2.2 signal
207 Carotid Artery Stenosis 9 2.2 2.2 signal
208 Skin Mass 17 2.2 2.2 signal
209 Oral Fungal Infection 7 2.1 2.1 no signal
210 Gout 45 2.1 2.1 signal
211 Rash Pruritic 135 2.1 2.1 signal
212 Rhinitis 20 2.1 2.1 signal
213 Joint Stiffness 65 2.1 2.1 signal
214 Knee Operation 24 2.1 2.1 signal
215 Exercise Tolerance Decreased 14 2.1 2.1 signal
216 Breast Disorder 5 2.1 2.1 no signal
217 Head Discomfort 43 2.1 2.1 signal
218 Meniscus Injury 15 2.1 2.1 signal
219 Mouth Swelling 14 2.1 2.1 signal
220 Drug Administered At Inappropriate Site 26 2.0 2.0 signal
221 Skin Warm 14 2.0 2.0 signal
222 Rash Generalised 63 2.0 2.0 signal
223 Myocardial Infarction 421 2.0 2.0 signal
224 Respiratory Tract Congestion 38 2.0 2.0 signal
225 Odynophagia 14 2.0 2.0 no signal
226 Therapy Interrupted 162 2.0 2.0 no signal
227 Injection Site Haematoma 34 2.0 2.0 no signal
228 Abnormal Faeces 19 2.0 2.0 no signal
229 Cardiac Flutter 15 1.9 2.0 no signal
230 Limb Operation 11 1.9 1.9 no signal
231 Immobile 10 1.9 1.9 no signal
232 Fear Of Injection 16 1.9 1.9 no signal
233 Prostatomegaly 9 1.9 1.9 no signal
234 Product Use Issue 427 1.9 1.9 no signal
235 Arteriospasm Coronary 9 1.9 1.9 no signal
236 Neck Pain 127 1.9 1.9 no signal
237 Colonoscopy 5 1.9 1.9 no signal
238 Shoulder Arthroplasty 6 1.9 1.9 no signal
239 Liver Function Test Increased 48 1.9 1.9 no signal
240 Back Pain 523 1.9 1.9 no signal
241 Immune System Disorder 29 1.9 1.9 no signal
242 Hypokinesia 32 1.9 1.9 no signal
243 Choking Sensation 12 1.8 1.8 no signal
244 Contusion 209 1.8 1.8 no signal
245 Hip Arthroplasty 33 1.8 1.8 no signal
246 Atrial Fibrillation 211 1.8 1.8 no signal
247 Ischaemia 10 1.8 1.8 no signal
248 Serum Sickness 6 1.8 1.8 no signal
249 Bone Pain 126 1.8 1.8 no signal
250 Lyme Disease 7 1.8 1.8 no signal
251 Fibromyalgia 51 1.8 1.8 no signal
252 Skin Atrophy 12 1.8 1.8 no signal
253 Muscle Strain 18 1.8 1.8 no signal
254 Vasculitis 24 1.7 1.7 no signal
255 Memory Impairment 283 1.7 1.7 no signal
256 Bronchitis 153 1.7 1.7 no signal
257 Tongue Discolouration 9 1.7 1.7 no signal
258 Drug Dose Omission 342 1.7 1.7 no signal
259 Tendon Disorder 13 1.7 1.7 no signal
260 Spinal Operation 24 1.7 1.7 no signal
261 Trigger Finger 8 1.7 1.7 no signal
262 Arteriosclerosis Coronary Artery 13 1.7 1.7 no signal
263 Ear Discomfort 20 1.6 1.6 no signal
264 Chromaturia 44 1.6 1.6 no signal
265 Laryngitis 21 1.6 1.6 no signal
266 Groin Pain 17 1.6 1.6 no signal
267 Brain Fog 28 1.6 1.6 no signal
268 Swollen Tongue 60 1.6 1.6 no signal
269 Skin Tightness 9 1.6 1.6 no signal
270 Hepatitis Toxic 5 1.6 1.6 no signal
271 Tongue Discomfort 8 1.6 1.6 no signal
272 Non-cardiac Chest Pain 6 1.6 1.6 no signal
273 Amnesia 123 1.6 1.6 no signal
274 Nasal Discomfort 15 1.6 1.6 no signal
275 Hip Surgery 10 1.6 1.6 no signal
276 Glucose Tolerance Impaired 11 1.6 1.6 no signal
277 Sluggishness 19 1.6 1.6 no signal
278 Musculoskeletal Stiffness 164 1.6 1.6 no signal
279 Hepatic Pain 8 1.6 1.6 no signal
280 Rash Vesicular 9 1.6 1.6 no signal
281 Alcohol Abuse 5 1.6 1.6 no signal
282 Increased Tendency To Bruise 17 1.6 1.6 no signal
283 Pruritus 696 1.5 1.6 no signal
284 Wrist Fracture 22 1.5 1.5 no signal
285 Throat Irritation 82 1.5 1.5 no signal
286 Injection Site Infection 6 1.5 1.5 no signal
287 Foot Operation 9 1.5 1.5 no signal
288 Knee Arthroplasty 38 1.5 1.5 no signal
289 Burning Sensation 127 1.5 1.5 no signal
290 Sinusitis 186 1.5 1.5 no signal
291 Prostatic Disorder 10 1.5 1.5 no signal
292 Skin Haemorrhage 26 1.5 1.5 no signal
293 Cerebrovascular Accident 304 1.5 1.5 no signal
294 Vulvovaginal Mycotic Infection 7 1.5 1.5 no signal
295 Urine Abnormality 8 1.5 1.5 no signal
296 Skin Odour Abnormal 7 1.5 1.5 no signal
297 Lip Swelling 59 1.5 1.5 no signal
298 Neuralgia 43 1.5 1.5 no signal
299 Furuncle 14 1.5 1.5 no signal
300 Cerebral Thrombosis 5 1.5 1.5 no signal
301 Pharyngitis 22 1.5 1.5 no signal
302 Cerebral Disorder 13 1.5 1.5 no signal
303 Feeling Abnormal 422 1.5 1.5 no signal
304 Musculoskeletal Chest Pain 27 1.5 1.5 no signal
305 Vitamin B12 Deficiency 7 1.5 1.5 no signal
306 Gait Disturbance 334 1.5 1.5 no signal
307 Fine Motor Skill Dysfunction 5 1.5 1.5 no signal
308 Anuria 15 1.5 1.5 no signal
309 Rosacea 8 1.5 1.5 no signal
310 Erythema Nodosum 6 1.4 1.4 no signal
311 Pollakiuria 71 1.4 1.4 no signal
312 Renal Pain 18 1.4 1.4 no signal
313 Spinal Disorder 16 1.4 1.4 no signal
314 Feeling Cold 47 1.4 1.4 no signal
315 Inappropriate Schedule Of Product Administration 296 1.4 1.4 no signal
316 Cataract 98 1.4 1.4 no signal
317 Device Malfunction 111 1.4 1.4 no signal
318 Hepatic Enzyme Increased 112 1.4 1.4 no signal
319 Dysstasia 48 1.4 1.4 no signal
320 Laboratory Test Abnormal 48 1.4 1.4 no signal
321 Tenderness 17 1.4 1.4 no signal
322 Blood Urine Present 31 1.4 1.4 no signal
323 Pain In Jaw 46 1.4 1.4 no signal
324 Chest Pain 301 1.4 1.4 no signal
325 Therapeutic Response Unexpected 73 1.4 1.4 no signal
326 Blepharospasm 10 1.4 1.4 no signal
327 Chronic Sinusitis 6 1.3 1.3 no signal
328 Condition Aggravated 482 1.3 1.3 no signal
329 Nasal Dryness 10 1.3 1.3 no signal
330 Hypersensitivity 293 1.3 1.3 no signal
331 Dementia 44 1.3 1.3 no signal
332 Bowel Movement Irregularity 12 1.3 1.3 no signal
333 Device Difficult To Use 104 1.3 1.3 no signal
334 Peripheral Swelling 241 1.3 1.3 no signal
335 Surgery 91 1.3 1.3 no signal
336 Pain 965 1.3 1.3 no signal
337 Urticaria 261 1.3 1.3 no signal
338 Autoimmune Disorder 15 1.3 1.3 no signal
339 Rash 679 1.3 1.3 no signal
340 Transient Ischaemic Attack 53 1.3 1.3 no signal
341 Cachexia 8 1.3 1.3 no signal
342 Seasonal Allergy 22 1.3 1.3 no signal
343 Diverticulitis 43 1.3 1.3 no signal
344 Limb Injury 42 1.3 1.3 no signal
345 Incorrect Route Of Product Administration 26 1.3 1.3 no signal
346 Chills 180 1.3 1.3 no signal
347 Paraesthesia Oral 22 1.3 1.3 no signal
348 Skin Discolouration 70 1.3 1.3 no signal
349 Bedridden 20 1.3 1.3 no signal
350 Energy Increased 9 1.3 1.3 no signal
351 Middle Insomnia 28 1.3 1.3 no signal
352 Peripheral Venous Disease 6 1.3 1.3 no signal
353 Fungal Skin Infection 6 1.3 1.3 no signal
354 Type 1 Diabetes Mellitus 9 1.3 1.3 no signal
355 Intracranial Aneurysm 6 1.3 1.3 no signal
356 Skin Reaction 21 1.3 1.3 no signal
357 Yellow Skin 7 1.3 1.3 no signal
358 Hypoacusis 64 1.3 1.3 no signal
359 Grip Strength Decreased 13 1.2 1.2 no signal
360 Incorrect Dose Administered 334 1.2 1.3 no signal
361 Feeling Hot 91 1.2 1.2 no signal
362 Dry Throat 15 1.2 1.2 no signal
363 Swelling Of Eyelid 9 1.2 1.2 no signal
364 Pharyngeal Oedema 23 1.2 1.2 no signal
365 Sarcoidosis 7 1.2 1.2 no signal
366 Swelling Face 95 1.2 1.2 no signal
367 Gastrointestinal Pain 16 1.2 1.2 no signal
368 Swelling 136 1.2 1.2 no signal
369 Leg Amputation 6 1.2 1.2 no signal
370 Myositis 13 1.2 1.2 no signal
371 Ear Pruritus 5 1.2 1.2 no signal
372 Shoulder Operation 6 1.2 1.2 no signal
373 Malaise 624 1.2 1.2 no signal
374 Blood Pressure Increased 217 1.2 1.2 no signal
375 Device Deployment Issue 17 1.2 1.2 no signal
376 Productive Cough 67 1.2 1.2 no signal
377 Brain Neoplasm 13 1.2 1.2 no signal
378 Erythema 290 1.2 1.2 no signal
379 Sleep Apnoea Syndrome 27 1.2 1.2 no signal
380 Nerve Compression 13 1.2 1.2 no signal
381 Mobility Decreased 101 1.2 1.2 no signal
382 Oral Mucosal Blistering 9 1.2 1.2 no signal
383 Hepatic Enzyme Abnormal 7 1.2 1.2 no signal
384 Haemorrhage Subcutaneous 5 1.2 1.2 no signal
385 Intervertebral Disc Disorder 6 1.2 1.2 no signal
386 Paralysis 20 1.2 1.2 no signal
387 Cardiac Valve Disease 8 1.2 1.2 no signal
388 Lethargy 80 1.2 1.2 no signal
389 Haematoma 36 1.2 1.2 no signal
390 Product Dispensing Error 30 1.2 1.2 no signal
391 Monoplegia 6 1.2 1.2 no signal
392 Tongue Disorder 10 1.2 1.2 no signal
393 Hypertriglyceridaemia 8 1.2 1.2 no signal
394 Aphonia 19 1.1 1.1 no signal
395 Blindness Transient 10 1.1 1.1 no signal
396 Abdominal Discomfort 227 1.1 1.1 no signal
397 Scratch 14 1.1 1.1 no signal
398 Hernia 26 1.1 1.1 no signal
399 Blood Glucose Abnormal 25 1.1 1.1 no signal
400 Cerebral Ischaemia 7 1.1 1.1 no signal
401 Taste Disorder 27 1.1 1.1 no signal
402 Arthropathy 75 1.1 1.1 no signal
403 Wheelchair User 6 1.1 1.1 no signal
404 Asthenia 501 1.1 1.1 no signal
405 Fatigue 1,033 1.1 1.1 no signal
406 Expired Product Administered 44 1.1 1.1 no signal
407 Kidney Infection 26 1.1 1.1 no signal
408 Bone Density Abnormal 5 1.1 1.1 no signal
409 Sciatica 21 1.1 1.1 no signal
410 Food Poisoning 7 1.1 1.1 no signal
411 Vertigo 80 1.1 1.1 no signal
412 Bladder Disorder 13 1.1 1.1 no signal
413 Blood Glucose Increased 247 1.1 1.1 no signal
414 Lacrimation Increased 39 1.1 1.1 no signal
415 Product Administration Interrupted 10 1.1 1.1 no signal
416 Product Dose Omission In Error 35 1.1 1.1 no signal
417 Dizziness 648 1.1 1.1 no signal
418 Muscle Twitching 30 1.1 1.1 no signal
419 Headache 811 1.1 1.1 no signal
420 Blood Potassium Increased 21 1.1 1.1 no signal
421 Tendon Rupture 16 1.1 1.1 no signal
422 Cognitive Disorder 60 1.1 1.1 no signal
423 Ocular Discomfort 14 1.1 1.1 no signal
424 Urinary Tract Infection 219 1.1 1.1 no signal
425 Tendonitis 20 1.1 1.1 no signal
426 Blister 72 1.1 1.1 no signal
427 Gastritis Erosive 6 1.1 1.1 no signal
428 Extrasystoles 9 1.1 1.1 no signal
429 Flank Pain 12 1.1 1.1 no signal
430 Rash Erythematous 60 1.1 1.1 no signal
431 Insurance Issue 19 1.1 1.1 no signal
432 Colitis Microscopic 6 1.1 1.1 no signal
433 Drug Intolerance 123 1.1 1.1 no signal
434 Hip Fracture 41 1.1 1.1 no signal
435 Movement Disorder 41 1.1 1.1 no signal
436 Discomfort 77 1.1 1.1 no signal
437 Arthritis 100 1.1 1.1 no signal
438 Dyspnoea 717 1.1 1.1 no signal
439 Hospitalisation 193 1.1 1.1 no signal
440 Rash Macular 44 1.1 1.1 no signal
441 Joint Injury 27 1.1 1.1 no signal
442 Diarrhoea 812 1.1 1.1 no signal
443 Blood Pressure Abnormal 25 1.1 1.1 no signal
444 Throat Tightness 34 1.1 1.1 no signal
445 Nocturia 15 1.0 1.0 no signal
446 Flatulence 70 1.0 1.0 no signal
447 Hypoaesthesia 185 1.0 1.0 no signal
448 Ear Pain 24 1.0 1.0 no signal
449 Facial Pain 11 1.0 1.0 no signal
450 Blood Test Abnormal 17 1.0 1.0 no signal
451 Walking Aid User 8 1.0 1.0 no signal
452 Musculoskeletal Disorder 23 1.0 1.0 no signal
453 Coronary Artery Stenosis 6 1.0 1.0 no signal
454 Vein Disorder 6 1.0 1.0 no signal
455 Sleep Disorder 83 1.0 1.0 no signal
456 Decreased Interest 7 1.0 1.0 no signal
457 Injection Site Nodule 13 1.0 1.0 no signal
458 Deafness 31 1.0 1.0 no signal
459 Hyperhidrosis 152 1.0 1.0 no signal
460 Skin Swelling 10 1.0 1.0 no signal
461 Macular Degeneration 14 1.0 1.0 no signal
462 Therapy Cessation 60 1.0 1.0 no signal
463 Blood Pressure Systolic Increased 23 1.0 1.0 no signal
464 Aphthous Ulcer 9 1.0 1.0 no signal
465 Vitamin D Decreased 10 1.0 1.0 no signal
466 Dysuria 43 1.0 1.0 no signal
467 Nerve Injury 13 1.0 1.0 no signal
468 Onychoclasis 8 1.0 1.0 no signal
469 Blood Pressure Fluctuation 28 1.0 1.0 no signal
470 Palpitations 136 1.0 1.0 no signal
471 Peripheral Vascular Disorder 6 1.0 1.0 no signal
472 Glomerular Filtration Rate Decreased 14 1.0 1.0 no signal
473 Petechiae 12 1.0 1.0 no signal
474 Tonsillitis 6 1.0 1.0 no signal
475 Chapped Lips 5 1.0 1.0 no signal
476 Acute Myocardial Infarction 34 1.0 1.0 no signal
477 Multiple Allergies 9 1.0 1.0 no signal
478 Dermatitis Contact 13 1.0 1.0 no signal
479 Cholecystectomy 13 1.0 1.0 no signal
480 Myasthenia Gravis 9 1.0 1.0 no signal
481 Therapy Change 11 1.0 1.0 no signal
482 Cold Sweat 20 1.0 1.0 no signal
483 Gastrointestinal Motility Disorder 6 1.0 1.0 no signal
484 Visual Impairment 139 1.0 0.9 no signal
485 Cystitis 36 0.9 0.9 no signal
486 Erectile Dysfunction 29 0.9 0.9 no signal
487 Incorrect Product Storage 15 0.9 0.9 no signal
488 Paraesthesia 177 0.9 0.9 no signal
489 Eye Haemorrhage 15 0.9 0.9 no signal
490 Abdominal Pain Upper 230 0.9 0.9 no signal
491 Device Use Error 38 0.9 0.9 no signal
492 Eye Swelling 41 0.9 0.9 no signal
493 Faeces Soft 8 0.9 0.9 no signal
494 Extra Dose Administered 44 0.9 0.9 no signal
495 Asphyxia 9 0.9 0.9 no signal
496 Heart Rate Irregular 25 0.9 0.9 no signal
497 Lower Limb Fracture 21 0.9 0.9 no signal
498 Upper Limb Fracture 22 0.9 0.9 no signal
499 Peripheral Coldness 15 0.9 0.9 no signal
500 Arthropod Bite 8 0.9 0.9 no signal
501 Hyperaesthesia 9 0.9 0.9 no signal
502 Gait Inability 36 0.9 0.9 no signal
503 Dry Mouth 88 0.9 0.9 no signal
504 Tinnitus 50 0.9 0.9 no signal
505 Ear Disorder 5 0.9 0.9 no signal
506 Hyperkeratosis 6 0.9 0.9 no signal
507 Initial Insomnia 11 0.9 0.9 no signal
508 Arthritis Infective 5 0.9 0.9 no signal
509 Oral Discomfort 15 0.9 0.9 no signal
510 Bursitis 13 0.9 0.9 no signal
511 Arrhythmia 51 0.9 0.9 no signal
512 Macular Oedema 6 0.9 0.9 no signal
513 Mass 15 0.9 0.9 no signal
514 Polyp 7 0.9 0.9 no signal
515 Abdominal Distension 111 0.9 0.9 no signal
516 Faeces Discoloured 23 0.9 0.9 no signal
517 Cardiovascular Disorder 27 0.9 0.9 no signal
518 Adverse Reaction 14 0.9 0.9 no signal
519 Toothache 19 0.9 0.9 no signal
520 Frequent Bowel Movements 28 0.9 0.9 no signal
521 Blood Uric Acid Increased 6 0.9 0.9 no signal
522 Generalised Erythema 6 0.9 0.9 no signal
523 Guillain-barre Syndrome 5 0.9 0.9 no signal
524 Cholelithiasis 34 0.9 0.9 no signal
525 Nail Disorder 9 0.9 0.9 no signal
526 Lymphoma 16 0.9 0.9 no signal
527 Atrioventricular Block 8 0.9 0.9 no signal
528 Eye Pruritus 34 0.9 0.9 no signal
529 Nephrolithiasis 47 0.9 0.9 no signal
530 Depressed Mood 54 0.9 0.9 no signal
531 Night Sweats 33 0.9 0.9 no signal
532 Skin Laceration 11 0.9 0.9 no signal
533 Thinking Abnormal 19 0.9 0.9 no signal
534 Thirst 18 0.8 0.8 no signal
535 Gastrointestinal Disorder 89 0.8 0.8 no signal
536 Blood Pressure Decreased 66 0.8 0.8 no signal
537 Confusional State 161 0.8 0.8 no signal
538 Balance Disorder 86 0.8 0.8 no signal
539 Sensory Loss 8 0.8 0.8 no signal
540 Nervousness 52 0.8 0.8 no signal
541 Inguinal Hernia 6 0.8 0.8 no signal
542 Pulmonary Congestion 13 0.8 0.8 no signal
543 Eye Infection 11 0.8 0.8 no signal
544 Needle Issue 28 0.8 0.8 no signal
545 Retinal Detachment 9 0.8 0.8 no signal
546 Body Temperature Increased 20 0.8 0.8 no signal
547 Upper Respiratory Tract Infection 45 0.8 0.8 no signal
548 Muscle Injury 8 0.8 0.8 no signal
549 Product Prescribing Error 23 0.8 0.8 no signal
550 Appendicitis 9 0.8 0.8 no signal
551 Benign Prostatic Hyperplasia 5 0.8 0.8 no signal
552 Dermatitis Allergic 12 0.8 0.8 no signal
553 Gastroenteritis 14 0.8 0.8 no signal
554 Weight Fluctuation 10 0.8 0.8 no signal
555 Neoplasm Malignant 64 0.8 0.8 no signal
556 Myocardial Ischaemia 11 0.8 0.8 no signal
557 Intervertebral Disc Protrusion 21 0.8 0.8 no signal
558 Oral Disorder 7 0.8 0.8 no signal
559 Gingival Bleeding 13 0.8 0.8 no signal
560 Nightmare 33 0.8 0.8 no signal
561 Lower Respiratory Tract Infection 43 0.8 0.8 no signal
562 Facial Paralysis 8 0.8 0.8 no signal
563 Feeling Jittery 18 0.8 0.8 no signal
564 Product Communication Issue 8 0.8 0.8 no signal
565 Weight Increased 209 0.8 0.8 no signal
566 Joint Swelling 113 0.8 0.8 no signal
567 Inflammation 48 0.8 0.8 no signal
568 Epistaxis 70 0.8 0.8 no signal
569 Restless Legs Syndrome 17 0.8 0.8 no signal
570 Viral Infection 31 0.8 0.8 no signal
571 Hypoaesthesia Oral 14 0.8 0.8 no signal
572 Hypertension 197 0.8 0.8 no signal
573 Parosmia 7 0.8 0.8 no signal
574 Alanine Aminotransferase Increased 57 0.8 0.8 no signal
575 Carpal Tunnel Syndrome 13 0.8 0.8 no signal
576 Back Injury 10 0.8 0.8 no signal
577 Covid-19 162 0.8 0.8 no signal
578 Acidosis 7 0.8 0.8 no signal
579 Aortic Aneurysm 7 0.8 0.8 no signal
580 Hospice Care 9 0.8 0.8 no signal
581 Ligament Sprain 9 0.8 0.8 no signal
582 Blood Glucose Fluctuation 10 0.8 0.8 no signal
583 Presyncope 22 0.8 0.8 no signal
584 Pancreatitis 48 0.8 0.8 no signal
585 Disturbance In Attention 49 0.8 0.8 no signal
586 Wrong Product Administered 6 0.8 0.8 no signal
587 Insomnia 241 0.8 0.8 no signal
588 Transaminases Increased 20 0.8 0.8 no signal
589 Renal Disorder 42 0.8 0.8 no signal
590 Ocular Hyperaemia 42 0.8 0.8 no signal
591 Gallbladder Disorder 16 0.8 0.8 no signal
592 Quality Of Life Decreased 12 0.8 0.8 no signal
593 Breast Mass 6 0.7 0.7 no signal
594 Blood Urea Increased 15 0.7 0.7 no signal
595 Cardiac Failure 71 0.7 0.7 no signal
596 Scab 10 0.7 0.7 no signal
597 Fall 293 0.7 0.7 no signal
598 Alopecia 173 0.7 0.7 no signal
599 Impaired Driving Ability 10 0.7 0.7 no signal
600 Scar 15 0.7 0.7 no signal
601 Ecchymosis 6 0.7 0.7 no signal
602 Sensory Disturbance 14 0.7 0.7 no signal
603 Autoimmune Hepatitis 6 0.7 0.7 no signal
604 Hair Growth Abnormal 6 0.7 0.7 no signal
605 Prostatic Specific Antigen Increased 12 0.7 0.7 no signal
606 Diabetes Mellitus 66 0.7 0.7 no signal
607 Road Traffic Accident 36 0.7 0.7 no signal
608 Erythema Multiforme 8 0.7 0.7 no signal
609 Polyuria 7 0.7 0.7 no signal
610 Spinal Pain 10 0.7 0.7 no signal
611 Rotator Cuff Syndrome 11 0.7 0.7 no signal
612 Blood Sodium Decreased 16 0.7 0.7 no signal
613 Squamous Cell Carcinoma 8 0.7 0.7 no signal
614 Blood Iron Decreased 10 0.7 0.7 no signal
615 Respiratory Tract Infection 22 0.7 0.7 no signal
616 Nausea 668 0.7 0.7 no signal
617 Sputum Discoloured 8 0.7 0.7 no signal
618 Illness 85 0.7 0.7 no signal
619 Oral Pain 19 0.7 0.7 no signal
620 Breast Pain 9 0.7 0.7 no signal
621 Foot Fracture 16 0.7 0.7 no signal
622 Skin Disorder 28 0.7 0.7 no signal
623 Eructation 16 0.7 0.7 no signal
624 Impaired Work Ability 18 0.7 0.7 no signal
625 Acute Coronary Syndrome 7 0.7 0.7 no signal
626 Hypersomnia 24 0.7 0.7 no signal
627 Hot Flush 63 0.7 0.7 no signal
628 Eczema 42 0.7 0.7 no signal
629 Dizziness Postural 8 0.7 0.7 no signal
630 Inappropriate Schedule Of Drug Administration 60 0.7 0.7 no signal
631 Ear Infection 22 0.7 0.7 no signal
632 Aspartate Aminotransferase Increased 44 0.7 0.7 no signal
633 Abdominal Pain Lower 21 0.7 0.7 no signal
634 Fluid Retention 42 0.7 0.7 no signal
635 Eye Disorder 27 0.7 0.7 no signal
636 Anaphylactic Shock 21 0.7 0.7 no signal
637 Skin Exfoliation 68 0.7 0.7 no signal
638 Hunger 11 0.7 0.7 no signal
639 Uterine Leiomyoma 6 0.7 0.7 no signal
640 Ulcer 13 0.7 0.7 no signal
641 Blood Magnesium Decreased 7 0.7 0.7 no signal
642 Skin Lesion 22 0.7 0.7 no signal
643 Heart Rate Increased 80 0.7 0.7 no signal
644 Hydronephrosis 6 0.7 0.7 no signal
645 Weight Decreased 223 0.7 0.7 no signal
646 Herpes Zoster 46 0.7 0.7 no signal
647 Vision Blurred 109 0.7 0.7 no signal
648 Blood Creatinine Increased 52 0.7 0.7 no signal
649 Food Allergy 6 0.7 0.7 no signal
650 Micturition Urgency 9 0.7 0.7 no signal
651 Product Distribution Issue 7 0.7 0.7 no signal
652 Haematuria 27 0.7 0.7 no signal
653 Anal Incontinence 7 0.7 0.7 no signal
654 Intentional Product Misuse 68 0.7 0.7 no signal
655 Blindness Unilateral 11 0.7 0.7 no signal
656 Thrombosis 63 0.7 0.7 no signal
657 Accidental Exposure To Product 78 0.7 0.7 no signal
658 Post Procedural Complication 15 0.7 0.7 no signal
659 Rib Fracture 16 0.7 0.7 no signal
660 Urinary Incontinence 23 0.7 0.7 no signal
661 Pyrexia 268 0.7 0.6 no signal
662 Gastroenteritis Viral 14 0.6 0.6 no signal
663 Product Odour Abnormal 8 0.6 0.6 no signal
664 Eye Pain 42 0.6 0.6 no signal
665 Disability 15 0.6 0.6 no signal
666 Loss Of Personal Independence In Daily Activities 36 0.6 0.6 no signal
667 Rash Papular 17 0.6 0.6 no signal
668 Accident 9 0.6 0.6 no signal
669 Intervertebral Disc Degeneration 7 0.6 0.6 no signal
670 Exposure Via Skin Contact 17 0.6 0.6 no signal
671 Product Administration Error 15 0.6 0.6 no signal
672 Dysgeusia 56 0.6 0.6 no signal
673 Tubulointerstitial Nephritis 14 0.6 0.6 no signal
674 Diarrhoea Haemorrhagic 7 0.6 0.6 no signal
675 Blood Glucose Decreased 36 0.6 0.6 no signal
676 Tremor 124 0.6 0.6 no signal
677 Increased Appetite 14 0.6 0.6 no signal
678 Rhabdomyolysis 31 0.6 0.6 no signal
679 Uterine Cancer 6 0.6 0.6 no signal
680 Dyspepsia 72 0.6 0.6 no signal
681 Laceration 7 0.6 0.6 no signal
682 Lymphadenopathy 26 0.6 0.6 no signal
683 Hypothyroidism 23 0.6 0.6 no signal
684 Vitamin D Deficiency 7 0.6 0.6 no signal
685 Formication 5 0.6 0.6 no signal
686 Decreased Appetite 166 0.6 0.6 no signal
687 Abdominal Pain 166 0.6 0.6 no signal
688 Ankle Fracture 11 0.6 0.6 no signal
689 Migraine 67 0.6 0.6 no signal
690 Speech Disorder 37 0.6 0.6 no signal
691 Localised Infection 17 0.6 0.6 no signal
692 Poor Quality Sleep 15 0.6 0.6 no signal
693 Intraocular Pressure Increased 9 0.6 0.6 no signal
694 Mental Impairment 17 0.6 0.6 no signal
695 Respiratory Disorder 21 0.6 0.6 no signal
696 Neuropathy Peripheral 66 0.6 0.6 no signal
697 Blood Potassium Decreased 21 0.6 0.6 no signal
698 Constipation 150 0.6 0.6 no signal
699 Apathy 10 0.6 0.6 no signal
700 Tooth Abscess 7 0.6 0.6 no signal
701 Eyelid Oedema 8 0.6 0.6 no signal
702 Abnormal Dreams 19 0.6 0.6 no signal
703 Haemoptysis 19 0.6 0.6 no signal
704 Dysphagia 64 0.6 0.6 no signal
705 Glaucoma 13 0.6 0.6 no signal
706 Chronic Obstructive Pulmonary Disease 35 0.6 0.6 no signal
707 Ataxia 8 0.6 0.6 no signal
708 Oral Herpes 13 0.6 0.6 no signal
709 Hyperlipidaemia 8 0.6 0.6 no signal
710 Haemorrhoids 13 0.6 0.6 no signal
711 Blood Bilirubin Increased 18 0.6 0.6 no signal
712 Mood Altered 18 0.6 0.6 no signal
713 Gastrooesophageal Reflux Disease 53 0.6 0.6 no signal
714 Fungal Infection 22 0.6 0.6 no signal
715 Aphasia 20 0.6 0.6 no signal
716 Irritable Bowel Syndrome 14 0.6 0.6 no signal
717 Cellulitis 33 0.5 0.5 no signal
718 Heart Rate Decreased 23 0.5 0.5 no signal
719 Syncope 65 0.5 0.5 no signal
720 Pharyngitis Streptococcal 7 0.5 0.5 no signal
721 Oedema Peripheral 79 0.5 0.5 no signal
722 Concussion 5 0.5 0.5 no signal
723 Renal Impairment 54 0.5 0.5 no signal
724 Personality Change 6 0.5 0.5 no signal
725 Dry Eye 31 0.5 0.5 no signal
726 Leukaemia 6 0.5 0.5 no signal
727 Head Injury 20 0.5 0.5 no signal
728 Cardiogenic Shock 9 0.5 0.5 no signal
729 Gastric Ulcer 12 0.5 0.5 no signal
730 Therapy Non-responder 28 0.5 0.5 no signal
731 Impaired Gastric Emptying 8 0.5 0.5 no signal
732 Skin Infection 7 0.5 0.5 no signal
733 Hepatitis 16 0.5 0.5 no signal
734 Atrial Flutter 5 0.5 0.5 no signal
735 Hyperthyroidism 9 0.5 0.5 no signal
736 Frustration Tolerance Decreased 5 0.5 0.5 no signal
737 Skin Ulcer 16 0.5 0.5 no signal
738 Choking 12 0.5 0.5 no signal
739 Hiatus Hernia 8 0.5 0.5 no signal
740 Vitreous Floaters 6 0.5 0.5 no signal
741 Internal Haemorrhage 7 0.5 0.5 no signal
742 Escherichia Infection 5 0.5 0.5 no signal
743 Retching 13 0.5 0.5 no signal
744 Renal Tubular Necrosis 6 0.5 0.5 no signal
745 Liver Disorder 27 0.5 0.5 no signal
746 Flushing 62 0.5 0.5 no signal
747 Pulmonary Mass 9 0.5 0.5 no signal
748 Complication Associated With Device 8 0.5 0.5 no signal
749 Disorientation 24 0.5 0.5 no signal
750 Pneumonia 195 0.5 0.5 no signal
751 Colon Cancer 9 0.5 0.5 no signal
752 Post Procedural Haemorrhage 7 0.5 0.5 no signal
753 Hemiplegia 5 0.5 0.5 no signal
754 Joint Range Of Motion Decreased 8 0.5 0.5 no signal
755 Abasia 15 0.5 0.5 no signal
756 Stress 43 0.5 0.5 no signal
757 Brain Injury 6 0.5 0.5 no signal
758 Activities Of Daily Living Impaired 12 0.5 0.5 no signal
759 Hepatic Function Abnormal 22 0.5 0.5 no signal
760 Polyneuropathy 7 0.5 0.5 no signal
761 Temperature Intolerance 6 0.5 0.5 no signal
762 Poor Quality Product Administered 6 0.5 0.5 no signal
763 Circulatory Collapse 10 0.5 0.5 no signal
764 Glossodynia 13 0.5 0.5 no signal
765 Hysterectomy 5 0.5 0.5 no signal
766 Diplopia 15 0.5 0.5 no signal
767 Ill-defined Disorder 35 0.5 0.5 no signal
768 Haemorrhage 60 0.5 0.5 no signal
769 Drug Hypersensitivity 111 0.5 0.5 no signal
770 Blood Calcium Increased 5 0.5 0.5 no signal
771 Generalised Oedema 7 0.5 0.5 no signal
772 Cyst 7 0.5 0.5 no signal
773 Dialysis 8 0.5 0.5 no signal
774 Gastrointestinal Infection 5 0.5 0.5 no signal
775 Oedema 30 0.5 0.5 no signal
776 Feeding Disorder 11 0.5 0.5 no signal
777 Photosensitivity Reaction 9 0.5 0.5 no signal
778 Tooth Fracture 6 0.5 0.5 no signal
779 Staphylococcal Infection 18 0.5 0.5 no signal
780 Respiratory Distress 15 0.5 0.5 no signal
781 Immunodeficiency 8 0.5 0.5 no signal
782 Depression 124 0.5 0.5 no signal
783 Rash Maculo-papular 12 0.5 0.5 no signal
784 Red Blood Cell Sedimentation Rate Increased 6 0.5 0.5 no signal
785 Foot Deformity 6 0.5 0.5 no signal
786 Blindness 22 0.5 0.5 no signal
787 Product Packaging Issue 5 0.5 0.5 no signal
788 Bacterial Infection 10 0.5 0.5 no signal
789 Liver Injury 13 0.5 0.5 no signal
790 Tooth Disorder 12 0.5 0.5 no signal
791 Intestinal Obstruction 20 0.4 0.4 no signal
792 Gastritis 14 0.4 0.4 no signal
793 Irritability 32 0.4 0.4 no signal
794 Dermatitis 11 0.4 0.4 no signal
795 Mitral Valve Incompetence 6 0.4 0.4 no signal
796 Eye Irritation 29 0.4 0.4 no signal
797 Wrong Technique In Product Usage Process 105 0.4 0.4 no signal
798 Gastric Disorder 18 0.4 0.4 no signal
799 Orthostatic Hypotension 9 0.4 0.4 no signal
800 Adverse Drug Reaction 46 0.4 0.4 no signal
801 Nervous System Disorder 16 0.4 0.4 no signal
802 Urinary Retention 17 0.4 0.4 no signal
803 Diabetes Mellitus Inadequate Control 9 0.4 0.4 no signal
804 Tachycardia 45 0.4 0.4 no signal
805 Ischaemic Stroke 9 0.4 0.4 no signal
806 Salivary Hypersecretion 5 0.4 0.4 no signal
807 Asthma 56 0.4 0.4 no signal
808 Acne 38 0.4 0.4 no signal
809 Incorrect Route Of Drug Administration 18 0.4 0.4 no signal
810 Hyperglycaemia 18 0.4 0.4 no signal
811 Vomiting 232 0.4 0.4 no signal
812 Hypoglycaemia 24 0.4 0.4 no signal
813 Cerebral Infarction 12 0.4 0.4 no signal
814 Bone Disorder 9 0.4 0.4 no signal
815 Rectal Haemorrhage 21 0.4 0.4 no signal
816 Euphoric Mood 5 0.4 0.4 no signal
817 Libido Decreased 6 0.4 0.4 no signal
818 Hepatic Steatosis 9 0.4 0.4 no signal
819 Tooth Extraction 6 0.4 0.4 no signal
820 Hepatic Cirrhosis 9 0.4 0.4 no signal
821 Liver Function Test Abnormal 14 0.4 0.4 no signal
822 Proteinuria 9 0.4 0.4 no signal
823 Angioedema 21 0.4 0.4 no signal
824 Type 2 Diabetes Mellitus 16 0.4 0.4 no signal
825 Anxiety 135 0.4 0.4 no signal
826 Procedural Pain 13 0.4 0.4 no signal
827 Decreased Activity 5 0.4 0.4 no signal
828 Panic Attack 17 0.4 0.4 no signal
829 Osteoporosis 19 0.4 0.4 no signal
830 Pulmonary Thrombosis 5 0.4 0.4 no signal
831 Loss Of Consciousness 58 0.4 0.4 no signal
832 Product Use Complaint 7 0.4 0.4 no signal
833 Lung Disorder 22 0.4 0.4 no signal
834 Stevens-johnson Syndrome 10 0.4 0.4 no signal
835 Dry Skin 59 0.4 0.4 no signal
836 Drug Ineffective 590 0.4 0.4 no signal
837 Cerebral Haemorrhage 16 0.4 0.4 no signal
838 Osteoarthritis 19 0.4 0.4 no signal
839 Somnolence 89 0.4 0.4 no signal
840 Gastrointestinal Carcinoma 4 0.4 0.4 no signal
841 Lung Neoplasm Malignant 18 0.4 0.4 no signal
842 Agitation 32 0.4 0.4 no signal
843 Blood Thyroid Stimulating Hormone Increased 4 0.4 0.4 no signal
844 Wound 12 0.4 0.4 no signal
845 Gastric Haemorrhage 5 0.4 0.4 no signal
846 Respiratory Arrest 12 0.4 0.4 no signal
847 Device Occlusion 6 0.4 0.4 no signal
848 Stomatitis 26 0.4 0.4 no signal
849 Nephropathy 4 0.4 0.4 no signal
850 Fracture 8 0.4 0.4 no signal
851 Ventricular Tachycardia 7 0.4 0.4 no signal
852 Product Use In Unapproved Indication 103 0.4 0.4 no signal
853 Drug-induced Liver Injury 13 0.4 0.4 no signal
854 Coagulopathy 7 0.4 0.4 no signal
855 Covid-19 Pneumonia 5 0.4 0.4 no signal
856 Dehydration 56 0.4 0.4 no signal
857 Candida Infection 7 0.4 0.4 no signal
858 Haematochezia 23 0.4 0.4 no signal
859 Impaired Quality Of Life 6 0.4 0.4 no signal
860 Product Quality Issue 56 0.3 0.3 no signal
861 Anosmia 6 0.3 0.3 no signal
862 Metabolic Acidosis 13 0.3 0.3 no signal
863 Hypotension 82 0.3 0.3 no signal
864 Infection 59 0.3 0.3 no signal
865 Cardiac Failure Congestive 33 0.3 0.3 no signal
866 Inflammatory Bowel Disease 4 0.3 0.3 no signal
867 Gamma-glutamyltransferase Increased 9 0.3 0.3 no signal
868 Pancreatitis Acute 9 0.3 0.3 no signal
869 Sepsis 45 0.3 0.3 no signal
870 Product Physical Issue 8 0.3 0.3 no signal
871 Spinal Fracture 8 0.3 0.3 no signal
872 Anaphylactic Reaction 22 0.3 0.3 no signal
873 Ageusia 10 0.3 0.3 no signal
874 Contraindicated Product Administered 12 0.3 0.3 no signal
875 Drug Eruption 7 0.3 0.3 no signal
876 Mental Status Changes 11 0.3 0.3 no signal
877 Device Failure 6 0.3 0.3 no signal
878 Dyskinesia 16 0.3 0.3 no signal
879 Oxygen Saturation Decreased 22 0.3 0.3 no signal
880 Product Prescribing Issue 8 0.3 0.3 no signal
881 Seizure 45 0.3 0.3 no signal
882 Infusion Site Pain 5 0.3 0.3 no signal
883 Blood Count Abnormal 6 0.3 0.3 no signal
884 Thyroid Disorder 6 0.3 0.3 no signal
885 Delusion 6 0.3 0.3 no signal
886 Red Blood Cell Count Decreased 11 0.3 0.3 no signal
887 Nodule 5 0.3 0.3 no signal
888 Accidental Overdose 14 0.3 0.3 no signal
889 Conjunctivitis 7 0.3 0.3 no signal
890 Adverse Event 35 0.3 0.3 no signal
891 Skin Burning Sensation 27 0.3 0.3 no signal
892 Mood Swings 12 0.3 0.3 no signal
893 Product Taste Abnormal 5 0.3 0.3 no signal
894 Skin Cancer 8 0.3 0.3 no signal
895 Sleep Disorder Due To A General Medical Condition 6 0.3 0.3 no signal
896 Jaundice 10 0.3 0.3 no signal
897 Pallor 10 0.3 0.3 no signal
898 Renal Failure 49 0.3 0.3 no signal
899 Cardiac Arrest 30 0.3 0.3 no signal
900 Hallucination 27 0.3 0.3 no signal
901 Hypertensive Crisis 4 0.3 0.3 no signal
902 Rheumatoid Arthritis 40 0.3 0.3 no signal
903 Chronic Kidney Disease 27 0.3 0.3 no signal
904 Skin Irritation 16 0.3 0.3 no signal
905 Subdural Haematoma 5 0.3 0.3 no signal
906 Incorrect Product Administration Duration 7 0.3 0.3 no signal
907 Off Label Use 299 0.3 0.3 no signal
908 Death 296 0.3 0.3 no signal
909 Hypoxia 12 0.3 0.3 no signal
910 Local Swelling 6 0.3 0.3 no signal
911 Pulmonary Hypertension 7 0.3 0.3 no signal
912 Mouth Ulceration 7 0.3 0.3 no signal
913 Osteomyelitis 6 0.3 0.3 no signal
914 Restlessness 12 0.3 0.3 no signal
915 Hepatic Cytolysis 4 0.3 0.3 no signal
916 Drug Dispensing Error 5 0.3 0.3 no signal
917 Blood Alkaline Phosphatase Increased 8 0.3 0.3 no signal
918 Photophobia 6 0.3 0.3 no signal
919 Ejection Fraction Decreased 5 0.3 0.3 no signal
920 Prostate Cancer 26 0.3 0.3 no signal
921 Application Site Pain 7 0.3 0.3 no signal
922 Pulmonary Fibrosis 6 0.3 0.3 no signal
923 Pulmonary Oedema 14 0.3 0.3 no signal
924 White Blood Cell Count Increased 12 0.3 0.3 no signal
925 Systemic Lupus Erythematosus 11 0.3 0.3 no signal
926 Pancreatic Carcinoma 9 0.3 0.3 no signal
927 Decreased Immune Responsiveness 3 0.3 0.3 no signal
928 Device Delivery System Issue 8 0.3 0.3 no signal
929 Hand Deformity 4 0.3 0.3 no signal
930 Coeliac Disease 3 0.3 0.3 no signal
931 Crying 11 0.3 0.3 no signal
932 Psychomotor Hyperactivity 5 0.3 0.3 no signal
933 Sars-cov-2 Test Positive 4 0.3 0.3 no signal
934 Malignant Melanoma 4 0.3 0.3 no signal
935 Face Oedema 5 0.2 0.2 no signal
936 Treatment Noncompliance 16 0.2 0.2 no signal
937 Anger 10 0.2 0.2 no signal
938 Eye Discharge 3 0.2 0.2 no signal
939 Hemiparesis 5 0.2 0.2 no signal
940 Drug Level Decreased 3 0.2 0.2 no signal
941 Poor Venous Access 3 0.2 0.2 no signal
942 Delirium 10 0.2 0.2 no signal
943 Bone Density Decreased 9 0.2 0.2 no signal
944 Device Leakage 12 0.2 0.2 no signal
945 Haemoglobin Decreased 29 0.2 0.2 no signal
946 Eating Disorder 6 0.2 0.2 no signal
947 Pleural Effusion 17 0.2 0.2 no signal
948 Clostridium Difficile Infection 6 0.2 0.2 no signal
949 Myelodysplastic Syndrome 4 0.2 0.2 no signal
950 Mental Disorder 12 0.2 0.2 no signal
951 Product Packaging Quantity Issue 3 0.2 0.2 no signal
952 Accidental Underdose 4 0.2 0.2 no signal
953 End Stage Renal Disease 5 0.2 0.2 no signal
954 General Physical Health Deterioration 31 0.2 0.2 no signal
955 Nephropathy Toxic 3 0.2 0.2 no signal
956 Colitis Ulcerative 12 0.2 0.2 no signal
957 Dysarthria 10 0.2 0.2 no signal
958 Acute Kidney Injury 40 0.2 0.2 no signal
959 Epilepsy 8 0.2 0.2 no signal
960 Pericardial Effusion 6 0.2 0.2 no signal
961 Product Substitution Issue 15 0.2 0.2 no signal
962 Breast Cancer 24 0.2 0.2 no signal
963 Disease Recurrence 12 0.2 0.2 no signal
964 Psoriatic Arthropathy 10 0.2 0.2 no signal
965 Impaired Healing 8 0.2 0.2 no signal
966 Pneumonia Aspiration 6 0.2 0.2 no signal
967 Therapeutic Product Effect Incomplete 17 0.2 0.2 no signal
968 Drug Interaction 38 0.2 0.2 no signal
969 Colitis 9 0.2 0.2 no signal
970 Cardio-respiratory Arrest 10 0.2 0.2 no signal
971 Psoriasis 31 0.2 0.2 no signal
972 Hepatic Failure 7 0.2 0.2 no signal
973 Device Breakage 9 0.2 0.2 no signal
974 Syringe Issue 4 0.2 0.2 no signal
975 Intentional Product Use Issue 20 0.2 0.2 no signal
976 Abnormal Behaviour 9 0.2 0.2 no signal
977 Emotional Disorder 7 0.2 0.2 no signal
978 Femur Fracture 7 0.2 0.2 no signal
979 Platelet Count Decreased 24 0.2 0.2 no signal
980 Therapeutic Product Effect Decreased 10 0.2 0.2 no signal
981 Product Availability Issue 5 0.2 0.2 no signal
982 Hair Texture Abnormal 3 0.2 0.2 no signal
983 Pain Of Skin 6 0.2 0.2 no signal
984 Fear 6 0.2 0.2 no signal
985 Pulmonary Embolism 21 0.2 0.2 no signal
986 C-reactive Protein Increased 8 0.2 0.2 no signal
987 Anaemia 40 0.2 0.2 no signal
988 Circumstance Or Information Capable Of Leading To Medication Error 7 0.2 0.2 no signal
989 International Normalised Ratio Increased 6 0.2 0.2 no signal
990 Bradycardia 11 0.2 0.2 no signal
991 Drug Prescribing Error 4 0.2 0.2 no signal
992 Gastrointestinal Haemorrhage 17 0.2 0.2 no signal
993 Hyperkalaemia 7 0.2 0.2 no signal
994 Haematemesis 5 0.2 0.2 no signal
995 Exposure During Pregnancy 12 0.2 0.2 no signal
996 Tooth Loss 4 0.2 0.2 no signal
997 Drug Effect Incomplete 7 0.2 0.2 no signal
998 Thrombocytopenia 21 0.2 0.2 no signal
999 Vaginal Haemorrhage 8 0.2 0.2 no signal
1000 Suicidal Ideation 17 0.2 0.2 no signal
1001 Multiple Fractures 3 0.2 0.2 no signal
1002 Leukopenia 9 0.2 0.2 no signal
1003 Plasma Cell Myeloma 7 0.2 0.2 no signal
1004 Incorrect Drug Administration Duration 5 0.1 0.1 no signal
1005 Hypokalaemia 8 0.1 0.1 no signal
1006 Ascites 5 0.1 0.1 no signal
1007 Injury 12 0.1 0.1 no signal
1008 Diabetic Ketoacidosis 4 0.1 0.1 no signal
1009 Withdrawal Syndrome 7 0.1 0.1 no signal
1010 Hepatic Cancer 4 0.1 0.1 no signal
1011 No Adverse Event 29 0.1 0.1 no signal
1012 Product Complaint 4 0.1 0.1 no signal
1013 Aggression 8 0.1 0.1 no signal
1014 Respiratory Failure 11 0.1 0.1 no signal
1015 Breast Cancer Female 4 0.1 0.1 no signal
1016 White Blood Cell Count Decreased 16 0.1 0.1 no signal
1017 Hyponatraemia 8 0.1 0.1 no signal
1018 Dermatitis Atopic 7 0.1 0.1 no signal
1019 Deep Vein Thrombosis 9 0.1 0.1 no signal
1020 Bladder Cancer 8 0.1 0.1 no signal
1021 Application Site Pruritus 3 0.1 0.1 no signal
1022 Pancytopenia 7 0.1 0.1 no signal
1023 Emotional Distress 15 0.1 0.1 no signal
1024 Drug Effect Decreased 6 0.1 0.1 no signal
1025 Treatment Failure 9 0.1 0.1 no signal
1026 Completed Suicide 9 0.1 0.1 no signal
1027 Disease Progression 12 0.1 0.1 no signal
1028 Renal Cancer 4 0.1 0.1 no signal
1029 Foetal Exposure During Pregnancy 6 0.1 0.1 no signal
1030 Toxicity To Various Agents 10 0.1 0.0 no signal
1031 Overdose 10 0.0 0.0 no signal
1032 Drug Dependence 6 0.0 0.0 no signal