Reaction

Increased Upper Airway Secretion reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 5,110 reports · 140 co-occurring drugs

As of the last recalculation, Increased Upper Airway Secretion appears in 5,110 FAERS reports alongside 140 co-occurring drug terms. The strongest observed disproportionality signal is SALMETEROL XINAFOATE (PRR 21.9).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Salmeterol Xinafoate	46	21.9	22.0
Mometasone	73	16.4	16.5
Ciclesonide	48	14.5	14.5
Fluticasone Propionate And Salmeterol	123	12.3	12.3
Mometasone Furoate	119	11.9	11.9
Ipratropium Bromide	100	11.6	11.7
Tiotropium Bromide	350	11.1	11.1
Alirocumab	63	10.3	10.4
Fluticasone Propionate Nasal	72	9.8	9.8
Olmesartan Medoxomil	84	9.7	9.7
Biotin	67	8.8	8.9
Budesonide And Formoterol Fumarate Dihydrate	199	8.6	8.7
Albuterol	227	8.0	8.0
Naproxen Sodium, Dextromethorphan Hydrobromide, Guaifenesin	37	7.4	7.4
Naproxen Sodium, Pseudoephedrine Hydrochloride	37	7.4	7.4
Palivizumab	26	6.9	6.9
Theophylline	19	6.8	6.8
Mepolizumab	81	6.7	6.7
Amlodipine Besylate And Benazepril Hydrochloride	15	6.6	6.6
Theophylline Anhydrous	20	6.6	6.6
Vitamin E	49	6.4	6.4
Antacid	73	6.3	6.3
Omalizumab	129	6.3	6.3
Budesonide	89	6.2	6.3
Guaifenesin	46	6.2	6.2
Albuterol Sulfate	416	6.1	6.1
Rosuvastatin Calcium	41	6.0	6.0
Fluticasone Propionate And Salmeterol Xinafoate	85	5.8	5.9
Fluticasone Propionate	176	5.7	5.7
Ascorbic Acid	32	5.6	5.6
Losartan Potassium And Hydrochlorothiazide	16	5.6	5.6
Montelukast Sodium	160	5.5	5.5
Tamsulosin Hydrochloride	27	5.4	5.4
Acetaminophen, Chlorpheniramine Maleate, Phenylephrine Hcl	64	5.3	5.3
Fluticasone Furoate And Vilanterol Trifenatate	46	5.2	5.3
Calcium Carbonate	83	5.1	5.1
Fluticasone Furoate	15	5.1	5.1
0Xygen	60	5.0	5.0
Oxygen	60	5.0	5.0
Dicyclomine Hydrochloride	17	4.9	4.9
Raloxifene Hydrochloride	17	4.8	4.8
Umeclidinium Bromide And Vilanterol Trifenatate	19	4.6	4.7
Umeclidinium	10	4.6	4.6
Acetylcysteine	10	4.3	4.3
Infliximab-Dyyb	30	4.2	4.2
Dronedarone	10	4.0	4.0
Calcium	142	4.0	4.0
Loratadine Tablet	51	3.9	3.9
Thyroid, Porcine	10	3.8	3.8
Esomeprazole Magnesium	213	3.8	3.8
Peginterferon Alfa-2A	50	3.8	3.8
Tofacitinib Citrate	12	3.7	3.7
Mometasone Furoate And Formoterol Fumarate Dihydrate	14	3.7	3.7
Lovastatin	23	3.7	3.7
Tiotropium Bromide Inhalation Spray	10	3.6	3.6
Diclofenac	75	3.6	3.6
Enalapril Maleate	21	3.5	3.5
Tobramycin	20	3.4	3.4
Tadalafil	82	3.4	3.4
Amlodipine Besylate And Valsartan	9	3.3	3.3
Valsartan And Hydrochlorothiazide	11	3.3	3.3
Psyllium Husk	8	3.3	3.3
Timolol Maleate	8	3.3	3.3
Azithromycin Dihydrate	47	3.3	3.3
Docusate Sodium 100Mg	19	3.2	3.2
Glyburide	19	3.2	3.2
Azithromycin	31	3.2	3.2
Etanercept	428	3.1	3.1
Vigabatrin	11	3.1	3.1
Butalbital, Acetaminophen, And Caffeine	8	3.1	3.1
Clopidogrel Bisulfate	76	3.1	3.1
Azithromycin Monohydrate	31	3.0	3.0
Ibuprofen And Diphenhydramine Citrate	17	3.0	3.0
Multivitamin	36	2.9	2.9
Human Insulin	9	2.9	2.9
Fish Oil	64	2.9	2.9
Ibuprofen Tablets, Coated	30	2.9	2.9
Varenicline Tartrate	56	2.9	2.9
Ibuprofen Sodium	30	2.9	2.9
Clobazam	17	2.8	2.8
Bosentan	35	2.8	2.8
Ibuprofen	184	2.8	2.8
Valsartan	72	2.8	2.8
Loratadine	73	2.8	2.8
Desoximetasone	13	2.8	2.8
Latanoprost	34	2.8	2.8
Fluticasone Furoate, Umeclidinium Bromide And Vilanterol Trifenatate	28	2.8	2.8
Dexlansoprazole	28	2.7	2.7
Gefitinib	6	2.7	2.7
Sotalol Hydrochloride	11	2.7	2.7
Rabeprazole Sodium	18	2.7	2.7
Clopidogrel	129	2.7	2.7
Rosuvastatin	130	2.6	2.6
Ribavirin	41	2.6	2.6
Adalimumab	429	2.6	2.6
Carboxymethylcellulose Sodium	6	2.6	2.6
Quinapril Hydrochloride	5	2.6	2.6
Atorvastatin Calcium	153	2.6	2.6
Loratadine And Pseudoephedrine Sulfate	5	2.6	2.6
Diclofenac Sodium	92	2.5	2.5
Metformin Hcl	34	2.5	2.5
Azelastine	11	2.5	2.5
Glipizide	37	2.5	2.5
Fexofenadine	10	2.5	2.5
Sulfasalazine	47	2.5	2.5
Estrogens, Conjugated	35	2.4	2.4
Conjugated Estrogens	34	2.4	2.4
Brinzolamide	5	2.3	2.3
Ocrelizumab	35	2.3	2.3
Epoprostenol	7	2.2	2.2
Niraparib	11	2.0	2.0
Iohexol	4	2.0	2.0
Dabigatran Etexilate Mesylate	34	1.9	1.9
Evolocumab	75	1.9	1.9
Fesoterodine Fumarate	5	1.9	1.9
Dornase Alfa	9	1.9	1.9
Exenatide	24	1.9	1.9
Rucaparib	4	1.8	1.8
Pirfenidone	18	1.8	1.8
Eptinezumab-Jjmr	4	1.8	1.8
Dabigatran Etexilate	34	1.8	1.8
Regorafenib	5	1.8	1.8
Nicotine Polacrilex	16	1.7	1.7
Naproxen Sodium Tablet	22	1.7	1.7
Teriparatide	46	1.7	1.7
Treprostinil	48	1.6	1.6
Dofetilide	4	1.6	1.6
Axitinib	7	1.5	1.5
Ambrisentan	44	1.4	1.4
Travoprost	3	1.4	1.4
Palbociclib	32	1.4	1.4
Belimumab	10	1.3	1.3
Crizotinib	4	1.3	1.3
Cannabidiol	7	1.2	1.2
Natalizumab	54	1.2	1.2
Ravulizumab	4	1.2	1.2
Budesonide, Glycopyrrolate, And Formoterol Fumarate	3	1.2	1.2
Onabotulinumtoxina	21	1.1	1.1
Lifitegrast	4	1.0	1.0
Nirmatrelvir And Ritonavir	11	0.8	0.8

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.