Reaction

Product Delivery Mechanism Issue reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 4,800 reports · 41 co-occurring drugs

As of the last recalculation, Product Delivery Mechanism Issue appears in 4,800 FAERS reports alongside 41 co-occurring drug terms. The strongest observed disproportionality signal is ALIROCUMAB (PRR 105.5).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Alirocumab	542	105.5	107.8
Azelastine	337	87.4	89.1
Budesonide, Glycopyrrolate, And Formoterol Fumarate	92	38.9	39.3
Fluticasone Propionate Nasal	251	37.8	38.1
Lifitegrast	118	32.1	32.3
Testosterone	153	29.3	29.5
Tiotropium Bromide Inhalation Spray	74	29.1	29.3
Daspone	58	26.1	26.3
Dapsone Gel, 5%	58	26.1	26.3
Ipratropium Bromide	199	25.2	25.3
Dapsone	58	23.8	24.0
Bimatoprost	123	19.0	19.0
Brimonidine Tartrate	72	17.8	17.8
Prednisolone Acetate	39	16.5	16.5
Mometasone	68	16.3	16.3
Travoprost	30	15.1	15.2
Esketamine Hydrochloride	60	14.8	14.8
Timolol Maleate	29	12.8	12.8
Triamcinolone Acetonide	80	11.4	11.4
Fluticasone Propionate	317	11.3	11.3
Carboxymethylcellulose Sodium	23	10.7	10.7
Latanoprost	92	8.1	8.1
Mometasone Furoate	69	7.3	7.3
Albuterol Sulfate	448	7.1	7.1
Cyclosporine	174	7.0	7.0
Dorzolamide Hydrochloride And Timolol Maleate	11	6.0	6.1
Moxifloxacin	14	4.3	4.3
Albuterol	113	4.2	4.2
Mometasone Furoate And Formoterol Fumarate Dihydrate	14	3.9	3.9
Timolol	10	3.6	3.6
Fluticasone Furoate	10	3.6	3.6
Brinzolamide	6	3.0	3.0
Diclofenac Sodium 1%	24	2.9	2.9
Diclofenac Sodium Topical	24	2.9	2.9
Diclofenac Sodium Topical Gel, 1%	24	2.9	2.9
Sumatriptan Succinate	16	2.8	2.8
Fluticasone Propionate And Salmeterol	18	1.9	1.9
Benralizumab	8	1.7	1.7
Docosanol	4	1.2	1.2
Glycerin, Lidocaine	3	0.9	0.9
Somatropin	15	0.9	0.9

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.