OpenPV Signal Explorer
FAERS disproportionality dashboard
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Drug

Doxepin

1,121 flagged reaction(s) · 46,445 total co-reports · max PRR 668.2
Important: Reactions below are the flagged terms from this drug’s FAERS report history (min. 3 co-reports per term) — PRR/ROR indicate disproportionality in spontaneous reporting, not causation. Data from FDA FAERS via openFDA. Last recalculated: 2026-09-14.
Reaction Co-reports (a) PRR ROR Signal
1 Junctional Ectopic Tachycardia 14 668.2 669.2 signal
2 Foramen Magnum Stenosis 10 253.4 253.6 signal
3 Sinobronchitis 16 246.9 247.3 signal
4 Osteoporosis Postmenopausal 14 229.9 230.2 signal
5 Urticaria Thermal 12 189.5 189.7 signal
6 Paranasal Sinus Inflammation 17 177.1 177.4 signal
7 Protein S Decreased 9 133.9 134.0 signal
8 Drug-genetic Interaction 19 127.9 128.1 signal
9 Iliotibial Band Syndrome 13 126.5 126.6 signal
10 Nail Avulsion 13 125.9 126.0 signal
11 Hydrocholecystis 9 105.6 105.6 signal
12 Corneal Reflex Decreased 17 98.6 98.7 signal
13 Peripheral Nerve Lesion 14 93.0 93.1 signal
14 Nasal Turbinate Hypertrophy 16 92.5 92.7 signal
15 Radial Nerve Palsy 14 84.8 84.9 signal
16 Congestive Hepatopathy 16 77.6 77.8 signal
17 Persistent Depressive Disorder 13 69.7 69.8 signal
18 Myofascial Pain Syndrome 23 69.2 69.4 signal
19 Bezoar 41 63.8 64.0 signal
20 Myosclerosis 11 63.6 63.7 signal
21 Vertebral Lesion 15 63.1 63.2 signal
22 Patellofemoral Pain Syndrome 15 62.3 62.4 signal
23 Chronic Spontaneous Urticaria 32 62.2 62.4 signal
24 Visceral Congestion 13 56.2 56.2 signal
25 Measles 13 51.4 51.5 signal
26 Mastocytosis 10 45.8 45.9 signal
27 Chronic Kidney Disease-mineral And Bone Disorder 23 45.4 45.5 signal
28 Dissociative Disorder 15 44.5 44.6 signal
29 Somatic Symptom Disorder 22 43.2 43.3 signal
30 Defaecation Disorder 13 41.4 41.5 signal
31 Mechanical Urticaria 9 41.0 41.1 signal
32 Albuminuria 9 35.8 35.8 signal
33 Urticaria Chronic 9 34.4 34.4 signal
34 Sleep-related Eating Disorder 15 33.8 33.8 signal
35 Reduced Facial Expression 14 29.5 29.5 signal
36 Rebound Acid Hypersecretion 42 28.9 29.0 signal
37 Multiple Drug Therapy 9 27.2 27.2 signal
38 Suspected Suicide 57 25.2 25.3 signal
39 Hyperparathyroidism Secondary 30 24.9 25.0 signal
40 Dysplasia 14 24.7 24.8 signal
41 Brugada Syndrome 12 24.7 24.7 signal
42 Nephrogenic Anaemia 54 24.3 24.4 signal
43 Pupillary Reflex Impaired 21 24.3 24.3 signal
44 Dysaesthesia 31 21.5 21.6 signal
45 Osteosclerosis 16 21.3 21.3 signal
46 Respiratory Depression 124 21.2 21.5 signal
47 Bladder Dilatation 11 21.2 21.2 signal
48 Kidney Enlargement 11 21.2 21.2 signal
49 Sedation Complication 25 21.0 21.1 signal
50 Electrocardiogram Qrs Complex Prolonged 49 20.1 20.2 signal
51 Restrictive Pulmonary Disease 11 19.8 19.8 signal
52 Anticholinergic Syndrome 15 19.8 19.8 signal
53 Neuroendocrine Carcinoma Of The Skin 9 19.4 19.4 signal
54 Nasal Septum Deviation 18 19.3 19.3 signal
55 Areflexia 24 18.7 18.8 signal
56 Bone Demineralisation 9 17.8 17.8 signal
57 Hypermetropia 8 17.6 17.6 signal
58 Mast Cell Activation Syndrome 11 17.4 17.4 signal
59 Cardiac Hypertrophy 9 17.0 17.0 signal
60 Stenosis 15 16.9 17.0 signal
61 Cardiac Aneurysm 8 16.9 16.9 signal
62 Substance Use 12 16.3 16.3 signal
63 Completed Suicide 638 15.9 16.9 signal
64 Acute Lung Injury 9 15.8 15.8 signal
65 Cystitis Noninfective 10 15.6 15.6 signal
66 Mastectomy 13 15.6 15.6 signal
67 Exposure Via Ingestion 19 15.6 15.6 signal
68 Alcohol Abuse 20 15.5 15.6 signal
69 Atrial Tachycardia 15 14.9 14.9 signal
70 Microcephaly 9 14.9 14.9 signal
71 Vitamin B12 Decreased 20 14.6 14.6 signal
72 Jaundice Neonatal 13 14.3 14.4 signal
73 Personality Disorder 18 14.3 14.3 signal
74 Abdominal Mass 17 13.3 13.3 signal
75 Bradypnoea 17 13.3 13.3 signal
76 Burns Second Degree 11 13.2 13.2 signal
77 Diastolic Dysfunction 19 12.8 12.8 signal
78 Dissociation 46 12.8 12.8 signal
79 Cartilage Injury 15 12.7 12.7 signal
80 Anxiety Disorder 20 12.5 12.5 signal
81 Chondropathy 16 12.2 12.3 signal
82 Pre-existing Condition Improved 36 11.9 12.0 signal
83 Cataplexy 8 11.7 11.7 signal
84 Sensitivity To Weather Change 29 11.6 11.6 signal
85 Cervical Vertebral Fracture 19 11.6 11.6 signal
86 Gallbladder Cancer 8 11.3 11.3 signal
87 Self Esteem Decreased 13 11.1 11.2 signal
88 Chronic Kidney Disease 408 11.1 11.6 signal
89 Pathological Fracture 27 11.1 11.1 signal
90 Blood Iron Increased 10 11.1 11.1 signal
91 Meniscus Injury 32 10.9 10.9 signal
92 Skin Wrinkling 14 10.8 10.8 signal
93 Snoring 19 10.5 10.5 signal
94 Toxicity To Various Agents 830 10.3 11.2 signal
95 Ventricular Arrhythmia 18 10.3 10.3 signal
96 Chronic Gastritis 11 10.3 10.3 signal
97 Brain Oedema 60 9.9 10.0 signal
98 Major Depression 34 9.7 9.7 signal
99 End Stage Renal Disease 85 9.6 9.7 signal
100 Hypertonic Bladder 13 9.4 9.4 signal
101 Psychotic Symptom 9 9.2 9.2 signal
102 Somnambulism 29 9.2 9.2 signal
103 Compulsive Shopping 9 9.1 9.1 signal
104 Humerus Fracture 21 9.1 9.1 signal
105 Iritis 13 8.9 8.9 signal
106 Facial Paresis 15 8.8 8.8 signal
107 Periodontitis 9 8.8 8.8 signal
108 Scratch 43 8.7 8.7 signal
109 Stupor 13 8.4 8.4 signal
110 Paresis 9 8.4 8.4 signal
111 Spinal Osteoarthritis 35 8.3 8.3 signal
112 Skin Plaque 33 8.2 8.2 signal
113 Left Ventricular Dysfunction 26 8.1 8.2 signal
114 Sinus Pain 9 8.1 8.2 signal
115 Ischaemic Cardiomyopathy 12 8.1 8.1 signal
116 Talipes 12 8.1 8.1 signal
117 Cardio-respiratory Arrest 162 8.0 8.2 signal
118 Affective Disorder 29 7.7 7.7 signal
119 Gastric Perforation 10 7.7 7.7 signal
120 Pneumonia Fungal 14 7.5 7.5 signal
121 Sleep Apnoea Syndrome 68 7.4 7.5 signal
122 Nocturia 43 7.4 7.4 signal
123 Pulmonary Congestion 47 7.4 7.4 signal
124 Fibromyalgia 85 7.3 7.4 signal
125 Tension Headache 15 7.3 7.3 signal
126 Facet Joint Syndrome 11 7.3 7.3 signal
127 Micturition Disorder 12 7.2 7.2 signal
128 Hypopnoea 12 7.2 7.2 signal
129 Intervertebral Disc Degeneration 32 7.2 7.2 signal
130 Generalised Tonic-clonic Seizure 56 7.1 7.2 signal
131 Infusion Site Haemorrhage 11 7.1 7.1 signal
132 Neonatal Respiratory Distress Syndrome 12 7.0 7.1 signal
133 Gambling Disorder 9 6.9 6.9 signal
134 Blood Immunoglobulin E Increased 8 6.9 6.9 signal
135 Osteopenia 50 6.8 6.9 signal
136 Hyperlipidaemia 39 6.8 6.8 signal
137 Endotracheal Intubation 9 6.7 6.7 signal
138 Small For Dates Baby 16 6.7 6.7 signal
139 Poisoning 40 6.6 6.6 signal
140 Drug Abuse 261 6.5 6.7 signal
141 Hepatosplenomegaly 8 6.5 6.5 signal
142 Aortic Arteriosclerosis 8 6.5 6.5 signal
143 Posture Abnormal 10 6.4 6.4 signal
144 Skin Injury 10 6.3 6.3 signal
145 Body Temperature Decreased 30 6.3 6.3 signal
146 Alcoholism 13 6.3 6.3 signal
147 Blood Potassium Abnormal 8 6.3 6.3 signal
148 Depressed Level Of Consciousness 118 6.2 6.3 signal
149 Umbilical Hernia 14 6.2 6.2 signal
150 Pigmentation Disorder 18 6.1 6.1 signal
151 Gastrointestinal Infection 26 6.1 6.1 signal
152 Cardiogenic Shock 41 6.0 6.0 signal
153 Hyperreflexia 10 6.0 6.0 signal
154 Post-traumatic Stress Disorder 19 5.9 5.9 signal
155 Blood Glucose Fluctuation 31 5.9 5.9 signal
156 Blood Pressure Systolic Increased 55 5.9 5.9 signal
157 Economic Problem 43 5.8 5.8 signal
158 Multiple Drug Overdose 14 5.8 5.8 signal
159 Autonomic Nervous System Imbalance 8 5.8 5.8 signal
160 Hepatic Lesion 12 5.8 5.8 signal
161 Lymphoedema 19 5.7 5.7 signal
162 Joint Effusion 19 5.7 5.7 signal
163 Intracranial Aneurysm 11 5.7 5.7 signal
164 Bradyphrenia 18 5.7 5.7 signal
165 Hypoventilation 9 5.7 5.7 signal
166 Product Administration Interrupted 21 5.7 5.7 signal
167 Enuresis 11 5.7 5.7 signal
168 Arthropod Bite 20 5.7 5.7 signal
169 Lyme Disease 9 5.7 5.7 signal
170 Hypothermia 27 5.6 5.6 signal
171 Rotator Cuff Syndrome 34 5.5 5.5 signal
172 Obesity 42 5.5 5.5 signal
173 Groin Pain 23 5.4 5.5 signal
174 Bundle Branch Block Left 11 5.4 5.4 signal
175 Idiopathic Pulmonary Fibrosis 10 5.4 5.4 signal
176 Ataxia 30 5.2 5.3 signal
177 Myoclonus 30 5.2 5.3 signal
178 Serotonin Syndrome 48 5.2 5.3 signal
179 Tongue Discolouration 11 5.2 5.2 signal
180 Drug Effect Increased 8 5.2 5.2 signal
181 Iron Deficiency 11 5.2 5.2 signal
182 Restless Legs Syndrome 45 5.2 5.2 signal
183 Intervertebral Disc Protrusion 54 5.1 5.2 signal
184 Tension 15 5.1 5.1 signal
185 Multiple Drug Overdose Intentional 8 5.1 5.1 signal
186 Gastrointestinal Motility Disorder 13 5.1 5.1 signal
187 Tendon Disorder 16 5.1 5.1 signal
188 Ligament Sprain 24 5.1 5.1 signal
189 Muscle Strain 21 5.1 5.1 signal
190 Spinal Disorder 23 5.1 5.1 signal
191 Anhedonia 64 5.0 5.1 signal
192 Retinopathy 9 5.0 5.0 signal
193 Scar 41 5.0 5.0 signal
194 Sensation Of Foreign Body 20 5.0 5.0 signal
195 Osteoarthritis 101 5.0 5.0 signal
196 Blood Pressure Diastolic Increased 11 4.9 5.0 signal
197 Skin Abrasion 11 4.9 4.9 signal
198 Impaired Gastric Emptying 30 4.9 4.9 signal
199 Neurodermatitis 8 4.8 4.8 signal
200 Blood Iron Decreased 27 4.8 4.8 signal
201 Sleep Disorder 159 4.7 4.8 signal
202 Suicide Attempt 138 4.7 4.8 signal
203 Renal Injury 68 4.7 4.7 signal
204 Middle Insomnia 42 4.7 4.7 signal
205 Vitamin D Deficiency 22 4.7 4.7 signal
206 Initial Insomnia 23 4.7 4.7 signal
207 Urticaria 373 4.7 4.8 signal
208 Bursitis 27 4.7 4.7 signal
209 Quality Of Life Decreased 30 4.7 4.7 signal
210 Bruxism 12 4.6 4.6 signal
211 Decreased Interest 13 4.6 4.6 signal
212 Concussion 17 4.6 4.6 signal
213 Supraventricular Tachycardia 21 4.6 4.6 signal
214 Goitre 9 4.6 4.6 signal
215 Uterine Leiomyoma 16 4.5 4.6 signal
216 Bundle Branch Block Right 10 4.5 4.5 signal
217 Feeling Of Despair 10 4.5 4.5 signal
218 Suicidal Ideation 197 4.5 4.5 signal
219 Furuncle 17 4.5 4.5 signal
220 Autoimmune Thyroiditis 8 4.4 4.4 signal
221 Mental Disorder 92 4.4 4.4 signal
222 Sedation 55 4.4 4.4 signal
223 Stress 151 4.4 4.4 signal
224 Drug Interaction 332 4.4 4.5 signal
225 Cyst 26 4.4 4.4 signal
226 Sciatica 33 4.3 4.3 signal
227 Neuralgia 50 4.3 4.3 signal
228 Pulmonary Haemorrhage 16 4.3 4.3 signal
229 Exposure Via Breast Milk 8 4.3 4.3 signal
230 Nonspecific Reaction 11 4.3 4.3 signal
231 Drooling 14 4.2 4.3 signal
232 Pancreatic Disorder 10 4.2 4.2 signal
233 Scab 23 4.2 4.2 signal
234 Renal Failure 271 4.2 4.3 signal
235 Stress Fracture 11 4.2 4.2 signal
236 Respiratory Rate Increased 18 4.2 4.2 signal
237 Hypernatraemia 10 4.2 4.2 signal
238 Pulmonary Oedema 89 4.1 4.2 signal
239 Creatinine Renal Clearance Decreased 8 4.1 4.1 signal
240 Intentional Overdose 124 4.1 4.1 signal
241 Cystitis 62 4.0 4.1 signal
242 Restlessness 71 4.0 4.1 signal
243 Dermatitis Contact 22 4.0 4.0 signal
244 Acute Kidney Injury 295 4.0 4.1 signal
245 Joint Injury 41 4.0 4.0 signal
246 Tenderness 20 4.0 4.0 signal
247 Spinal Compression Fracture 16 4.0 4.0 signal
248 Immune System Disorder 25 4.0 4.0 signal
249 Hordeolum 8 4.0 4.0 signal
250 Nephrotic Syndrome 13 4.0 4.0 signal
251 Mental Impairment 46 3.9 4.0 signal
252 Pharyngeal Swelling 18 3.9 3.9 signal
253 Osteomyelitis 34 3.9 3.9 signal
254 Hypervolaemia 9 3.9 3.9 signal
255 Anal Fistula 10 3.9 3.9 signal
256 Drug Withdrawal Syndrome Neonatal 28 3.9 3.9 signal
257 Skin Haemorrhage 27 3.9 3.9 signal
258 Hepatic Pain 8 3.9 3.9 signal
259 Respiratory Arrest 52 3.9 3.9 signal
260 Vitamin D Decreased 16 3.9 3.9 signal
261 Food Allergy 14 3.9 3.9 signal
262 Gingivitis 10 3.9 3.9 signal
263 Hyperprolactinaemia 12 3.8 3.8 signal
264 Seasonal Allergy 26 3.8 3.8 signal
265 Impaired Work Ability 39 3.8 3.8 signal
266 Tubulointerstitial Nephritis 34 3.8 3.8 signal
267 Protein Urine Present 9 3.8 3.8 signal
268 Angioedema 79 3.7 3.8 signal
269 Panic Attack 65 3.7 3.7 signal
270 Irritable Bowel Syndrome 38 3.7 3.7 signal
271 Depression 404 3.7 3.8 signal
272 Lumbar Vertebral Fracture 8 3.7 3.7 signal
273 Inadequate Analgesia 15 3.6 3.6 signal
274 Osteoporosis 72 3.6 3.7 signal
275 Fracture 33 3.6 3.6 signal
276 Obsessive-compulsive Disorder 14 3.6 3.6 signal
277 Renal Tubular Necrosis 17 3.6 3.6 signal
278 Skin Necrosis 9 3.6 3.6 signal
279 Papule 12 3.6 3.6 signal
280 Therapy Partial Responder 26 3.6 3.6 signal
281 Cardiac Murmur 15 3.6 3.6 signal
282 Defaecation Urgency 12 3.6 3.6 signal
283 Dental Caries 19 3.6 3.6 signal
284 Poisoning Deliberate 16 3.6 3.6 signal
285 Encephalopathy 42 3.6 3.6 signal
286 Gastritis 45 3.6 3.6 signal
287 Upper-airway Cough Syndrome 14 3.6 3.6 signal
288 Muscle Spasticity 21 3.5 3.5 signal
289 Disturbance In Attention 91 3.5 3.5 signal
290 Anorectal Discomfort 9 3.5 3.5 signal
291 Unresponsive To Stimuli 43 3.5 3.5 signal
292 Electrocardiogram Qt Prolonged 60 3.5 3.5 signal
293 Angina Pectoris 48 3.5 3.5 signal
294 Hormone Level Abnormal 8 3.5 3.5 signal
295 Coma 79 3.5 3.5 signal
296 Rib Fracture 34 3.5 3.5 signal
297 Drug Screen Positive 13 3.4 3.4 signal
298 Bipolar Disorder 18 3.4 3.4 signal
299 Cold Sweat 29 3.4 3.4 signal
300 Periorbital Swelling 9 3.4 3.4 signal
301 Swelling Of Eyelid 10 3.4 3.4 signal
302 Foot Fracture 31 3.4 3.4 signal
303 Hyperkeratosis 9 3.4 3.4 signal
304 Fear 44 3.4 3.4 signal
305 Concomitant Disease Aggravated 10 3.4 3.4 signal
306 Hiatus Hernia 21 3.4 3.4 signal
307 Intracranial Pressure Increased 9 3.4 3.4 signal
308 Obstructive Airways Disorder 18 3.4 3.4 signal
309 Scoliosis 10 3.4 3.4 signal
310 Diabetic Neuropathy 8 3.3 3.3 signal
311 Muscle Twitching 37 3.3 3.3 signal
312 Nephropathy 15 3.3 3.3 signal
313 Insomnia 426 3.3 3.4 signal
314 Brain Injury 16 3.3 3.3 signal
315 Status Epilepticus 18 3.3 3.3 signal
316 Activated Partial Thromboplastin Time Prolonged 8 3.3 3.3 signal
317 Facial Pain 14 3.3 3.3 signal
318 Temperature Intolerance 16 3.3 3.3 signal
319 Atelectasis 15 3.2 3.2 signal
320 Muscle Tightness 25 3.2 3.2 signal
321 Benign Prostatic Hyperplasia 8 3.2 3.2 signal
322 Symptom Recurrence 9 3.2 3.2 signal
323 Glucose Tolerance Impaired 9 3.2 3.2 signal
324 Cardiomegaly 19 3.2 3.2 signal
325 Torsade De Pointes 12 3.2 3.2 signal
326 Gastrooesophageal Reflux Disease 122 3.2 3.2 signal
327 Mania 25 3.2 3.2 signal
328 Movement Disorder 49 3.2 3.2 signal
329 Wound 42 3.1 3.2 signal
330 Dry Mouth 122 3.1 3.2 signal
331 Mass 21 3.1 3.1 signal
332 Frustration Tolerance Decreased 12 3.1 3.1 signal
333 Haemorrhoids 29 3.1 3.1 signal
334 Postoperative Wound Infection 10 3.1 3.1 signal
335 Depressed Mood 78 3.1 3.1 signal
336 Tardive Dyskinesia 42 3.1 3.1 signal
337 Inguinal Hernia 9 3.1 3.1 signal
338 Cholecystitis Chronic 10 3.1 3.1 signal
339 Substance Abuse 12 3.1 3.1 signal
340 Acute Hepatic Failure 20 3.1 3.1 signal
341 Back Disorder 24 3.1 3.1 signal
342 Laceration 14 3.1 3.1 signal
343 Infusion Site Swelling 9 3.0 3.0 signal
344 Infective Pulmonary Exacerbation Of Cystic Fibrosis 8 3.0 3.0 signal
345 Anaphylactic Reaction 80 3.0 3.0 signal
346 Ecchymosis 10 3.0 3.0 signal
347 Multiple Fractures 24 3.0 3.0 signal
348 Urinary Retention 48 3.0 3.0 signal
349 Anxiety 411 3.0 3.1 signal
350 Vitreous Floaters 14 3.0 3.0 signal
351 Impaired Healing 47 3.0 3.0 signal
352 Bronchitis 106 3.0 3.0 signal
353 Wrist Fracture 17 3.0 3.0 signal
354 Lip Swelling 47 2.9 3.0 signal
355 Diverticulitis 39 2.9 2.9 signal
356 Breast Pain 15 2.9 2.9 signal
357 Sinus Congestion 19 2.9 2.9 signal
358 Limb Injury 38 2.9 2.9 signal
359 Photosensitivity Reaction 23 2.9 2.9 signal
360 Night Sweats 45 2.9 2.9 signal
361 Musculoskeletal Discomfort 24 2.9 2.9 signal
362 Mouth Swelling 8 2.9 2.9 signal
363 Hypertonia 8 2.9 2.9 signal
364 Panic Reaction 10 2.9 2.9 signal
365 Hallucination, Auditory 22 2.9 2.9 signal
366 Hypokinesia 20 2.9 2.9 signal
367 Brain Fog 20 2.9 2.9 signal
368 Migraine 130 2.9 2.9 signal
369 Autoimmune Disorder 13 2.8 2.8 signal
370 Cardiac Failure Acute 9 2.8 2.8 signal
371 Blood Triglycerides Increased 24 2.8 2.8 signal
372 Product Prescribing Error 32 2.8 2.8 signal
373 Decubitus Ulcer 11 2.8 2.8 signal
374 Therapy Change 13 2.8 2.8 signal
375 Tinnitus 62 2.8 2.8 signal
376 Pulmonary Mass 20 2.8 2.8 signal
377 Hypertensive Crisis 15 2.8 2.8 signal
378 Sinus Tachycardia 19 2.8 2.8 signal
379 Somnolence 269 2.8 2.8 signal
380 Hereditary Angioedema 14 2.8 2.8 signal
381 Full Blood Count Abnormal 14 2.8 2.8 signal
382 Nightmare 46 2.8 2.8 signal
383 Micturition Urgency 15 2.8 2.8 signal
384 Bradycardia 70 2.7 2.8 signal
385 Poor Quality Sleep 28 2.7 2.7 signal
386 Hypoalbuminaemia 10 2.7 2.7 signal
387 Haematoma 34 2.7 2.7 signal
388 Tachycardia 116 2.7 2.7 signal
389 Aortic Aneurysm 10 2.7 2.7 signal
390 Neck Pain 73 2.7 2.7 signal
391 Electrolyte Imbalance 15 2.7 2.7 signal
392 Dysarthria 49 2.7 2.7 signal
393 Sinusitis 133 2.7 2.7 signal
394 Choking 25 2.7 2.7 signal
395 Emphysema 13 2.7 2.7 signal
396 Pneumonia Aspiration 32 2.7 2.7 signal
397 Carpal Tunnel Syndrome 18 2.7 2.7 signal
398 Thinking Abnormal 24 2.7 2.7 signal
399 Grand Mal Convulsion 12 2.7 2.7 signal
400 Inappropriate Antidiuretic Hormone Secretion 13 2.7 2.7 signal
401 Multiple Allergies 10 2.7 2.7 signal
402 Pollakiuria 53 2.7 2.7 signal
403 Pruritus 480 2.6 2.7 signal
404 Immunosuppression 11 2.6 2.6 signal
405 Rash Macular 44 2.6 2.6 signal
406 Skin Disorder 42 2.6 2.6 signal
407 Gastric Ulcer 24 2.6 2.6 signal
408 Ventricular Fibrillation 14 2.6 2.6 signal
409 Drug Ineffective For Unapproved Indication 70 2.6 2.6 signal
410 Blood Pressure Increased 192 2.6 2.6 signal
411 Paraesthesia Oral 18 2.6 2.6 signal
412 Nasal Congestion 73 2.6 2.6 signal
413 Arrhythmia 59 2.6 2.6 signal
414 Hepatic Steatosis 23 2.6 2.6 signal
415 Cardiac Flutter 8 2.6 2.6 signal
416 Cholecystectomy 14 2.6 2.6 signal
417 Metabolic Acidosis 39 2.6 2.6 signal
418 Incoherent 8 2.6 2.6 signal
419 Bone Density Decreased 39 2.6 2.6 signal
420 Parkinsonism 12 2.6 2.6 signal
421 Shock Haemorrhagic 10 2.6 2.6 signal
422 Metastases To Bone 20 2.5 2.5 signal
423 Cardiac Arrest 101 2.5 2.6 signal
424 Hepatomegaly 12 2.5 2.5 signal
425 Tooth Infection 16 2.5 2.5 signal
426 Skin Lesion 33 2.5 2.5 signal
427 Sunburn 9 2.5 2.5 signal
428 Bladder Disorder 12 2.5 2.5 signal
429 Hydronephrosis 9 2.5 2.5 signal
430 Salivary Hypersecretion 12 2.5 2.5 signal
431 Back Injury 13 2.5 2.5 signal
432 Metastases To Liver 21 2.5 2.5 signal
433 Iron Deficiency Anaemia 11 2.5 2.5 signal
434 Aggression 60 2.5 2.5 signal
435 Hypothyroidism 38 2.5 2.5 signal
436 Pulmonary Thrombosis 13 2.5 2.5 signal
437 Motor Dysfunction 12 2.5 2.5 signal
438 Type 2 Diabetes Mellitus 40 2.5 2.5 signal
439 Dyspepsia 116 2.5 2.5 signal
440 Dermatitis Atopic 59 2.5 2.5 signal
441 Drug Prescribing Error 23 2.5 2.5 signal
442 Intentional Drug Misuse 25 2.5 2.5 signal
443 Maternal Exposure Before Pregnancy 8 2.5 2.5 signal
444 Fall 390 2.4 2.5 signal
445 Blood Count Abnormal 18 2.4 2.4 signal
446 Apathy 17 2.4 2.4 signal
447 Ankle Fracture 18 2.4 2.4 signal
448 Altered State Of Consciousness 25 2.4 2.4 signal
449 Syncope 116 2.4 2.4 signal
450 Blood Cholesterol Increased 54 2.4 2.4 signal
451 Spinal Operation 14 2.4 2.4 signal
452 Myopathy 10 2.4 2.4 signal
453 Hypersomnia 33 2.4 2.4 signal
454 Hepatitis C 14 2.4 2.4 signal
455 Joint Stiffness 30 2.4 2.4 signal
456 Pruritus Generalised 25 2.4 2.4 signal
457 Ileus 14 2.4 2.4 signal
458 Weight Decreased 317 2.4 2.4 signal
459 Hallucination 85 2.4 2.4 signal
460 Injury 80 2.4 2.4 signal
461 Renal Cyst 9 2.4 2.4 signal
462 Bacterial Infection 21 2.4 2.4 signal
463 Acute Respiratory Distress Syndrome 20 2.4 2.4 signal
464 Cardiotoxicity 10 2.3 2.3 signal
465 Photophobia 21 2.3 2.3 signal
466 Pharyngitis 14 2.3 2.3 signal
467 Dyspnoea Exertional 42 2.3 2.3 signal
468 Staphylococcal Infection 37 2.3 2.3 signal
469 Skin Laceration 12 2.3 2.3 signal
470 Diverticulum 8 2.3 2.3 signal
471 Toothache 20 2.3 2.3 signal
472 Weight Increased 245 2.3 2.3 signal
473 Akathisia 15 2.3 2.3 signal
474 Hyperaesthesia 9 2.3 2.3 signal
475 Drug Use Disorder 9 2.3 2.3 signal
476 Nerve Compression 10 2.3 2.3 signal
477 Hypertension 230 2.3 2.3 signal
478 Psychotic Disorder 32 2.3 2.3 signal
479 Foot Deformity 12 2.3 2.3 signal
480 Seizure 124 2.2 2.3 signal
481 Haematuria 37 2.2 2.3 signal
482 Tooth Abscess 11 2.2 2.2 signal
483 Road Traffic Accident 45 2.2 2.2 signal
484 Glomerular Filtration Rate Decreased 13 2.2 2.2 signal
485 Feeling Drunk 8 2.2 2.2 signal
486 Kidney Infection 21 2.2 2.2 signal
487 Personality Change 10 2.2 2.2 signal
488 Cholelithiasis 35 2.2 2.2 signal
489 Skin Reaction 15 2.2 2.2 signal
490 Cataract 63 2.2 2.2 signal
491 Dermatitis 22 2.2 2.2 signal
492 Heart Rate Increased 105 2.2 2.2 signal
493 Mitral Valve Incompetence 12 2.2 2.2 signal
494 Tremor 176 2.2 2.2 signal
495 Weight Fluctuation 11 2.2 2.2 signal
496 Nasopharyngitis 195 2.2 2.2 signal
497 Burning Sensation 74 2.2 2.2 signal
498 Eczema 53 2.2 2.2 signal
499 Hip Arthroplasty 16 2.2 2.2 signal
500 Haematochezia 58 2.2 2.2 signal
501 Hyponatraemia 59 2.2 2.2 signal
502 Nephrolithiasis 48 2.2 2.2 signal
503 Gastroenteritis Viral 19 2.2 2.2 signal
504 Wheezing 62 2.2 2.2 signal
505 Bronchospasm 15 2.2 2.2 signal
506 Treatment Failure 86 2.2 2.2 signal
507 Nervousness 55 2.2 2.2 signal
508 Urinary Incontinence 31 2.2 2.2 signal
509 Peripheral Swelling 160 2.2 2.2 signal
510 Memory Impairment 143 2.2 2.2 signal
511 Overdose 225 2.2 2.2 signal
512 Loss Of Consciousness 133 2.2 2.2 signal
513 Cognitive Disorder 48 2.1 2.2 signal
514 Dystonia 20 2.1 2.1 signal
515 Lethargy 59 2.1 2.1 signal
516 Pain In Jaw 29 2.1 2.1 signal
517 Viral Infection 34 2.1 2.1 signal
518 Discomfort 62 2.1 2.1 signal
519 Therapeutic Response Unexpected 46 2.1 2.1 signal
520 Upper Respiratory Tract Infection 47 2.1 2.1 signal
521 Oropharyngeal Pain 94 2.1 2.1 signal
522 Productive Cough 48 2.1 2.1 signal
523 Cardiomyopathy 15 2.1 2.1 signal
524 Laryngitis 11 2.1 2.1 signal
525 Inflammation 52 2.1 2.1 signal
526 Feeling Abnormal 243 2.1 2.1 signal
527 Thirst 18 2.1 2.1 signal
528 Flatulence 57 2.1 2.1 signal
529 Pulmonary Hypertension 21 2.1 2.1 signal
530 Miosis 8 2.1 2.1 no signal
531 Rash Erythematous 47 2.1 2.1 signal
532 Hypoaesthesia Oral 15 2.1 2.1 signal
533 Swelling 93 2.1 2.1 signal
534 Malnutrition 11 2.1 2.1 signal
535 Skin Infection 11 2.1 2.1 signal
536 Swelling Face 64 2.0 2.1 signal
537 Product Availability Issue 22 2.0 2.0 signal
538 Therapeutic Response Decreased 59 2.0 2.0 signal
539 Small Intestinal Obstruction 12 2.0 2.0 signal
540 Back Pain 227 2.0 2.1 signal
541 Device Related Infection 15 2.0 2.0 signal
542 Euphoric Mood 10 2.0 2.0 signal
543 Constipation 210 2.0 2.0 signal
544 Musculoskeletal Chest Pain 15 2.0 2.0 signal
545 Arthropathy 54 2.0 2.0 signal
546 Intentional Product Misuse 84 2.0 2.0 signal
547 Respiratory Disorder 29 2.0 2.0 signal
548 Impaired Driving Ability 11 2.0 2.0 signal
549 Diabetes Mellitus 74 2.0 2.0 signal
550 Drug Level Increased 16 2.0 2.0 signal
551 Feeling Hot 59 2.0 2.0 signal
552 Mood Altered 26 2.0 2.0 no signal
553 Illness 96 2.0 2.0 no signal
554 Proteinuria 18 2.0 2.0 no signal
555 Arteriosclerosis 9 2.0 2.0 no signal
556 Gait Disturbance 183 2.0 2.0 no signal
557 Feeding Disorder 19 2.0 2.0 no signal
558 Coronary Artery Disease 29 2.0 2.0 no signal
559 Head Injury 30 2.0 2.0 no signal
560 Joint Dislocation 10 2.0 2.0 no signal
561 Withdrawal Syndrome 40 2.0 2.0 no signal
562 Eye Swelling 35 2.0 2.0 no signal
563 Loss Of Personal Independence In Daily Activities 45 2.0 2.0 no signal
564 Therapeutic Response Shortened 30 2.0 2.0 no signal
565 Lower Limb Fracture 18 2.0 2.0 no signal
566 Anger 32 2.0 2.0 no signal
567 Sexual Dysfunction 11 2.0 2.0 no signal
568 Leukocytosis 17 2.0 2.0 no signal
569 Unevaluable Event 71 2.0 2.0 no signal
570 Hypomagnesaemia 13 2.0 2.0 no signal
571 Contusion 90 1.9 2.0 no signal
572 White Blood Cell Count Increased 36 1.9 1.9 no signal
573 C-reactive Protein Increased 34 1.9 1.9 no signal
574 Fungal Infection 31 1.9 1.9 no signal
575 Prescribed Overdose 18 1.9 1.9 no signal
576 Emotional Distress 113 1.9 1.9 no signal
577 Lower Respiratory Tract Infection 42 1.9 1.9 no signal
578 Polyneuropathy 11 1.9 1.9 no signal
579 Accident 11 1.9 1.9 no signal
580 Paranoia 16 1.9 1.9 no signal
581 Agitation 68 1.9 1.9 no signal
582 Oral Candidiasis 12 1.9 1.9 no signal
583 Dysstasia 27 1.9 1.9 no signal
584 Ankylosing Spondylitis 12 1.9 1.9 no signal
585 Hyperhidrosis 118 1.9 1.9 no signal
586 Dialysis 13 1.9 1.9 no signal
587 Dyskinesia 37 1.9 1.9 no signal
588 Blood Calcium Increased 8 1.9 1.9 no signal
589 Disability 18 1.9 1.9 no signal
590 Thyroid Disorder 14 1.9 1.9 no signal
591 Red Blood Cell Count Decreased 26 1.9 1.9 no signal
592 Urinary Tract Infection 154 1.9 1.9 no signal
593 Abdominal Pain Upper 186 1.9 1.9 no signal
594 Abnormal Behaviour 36 1.9 1.9 no signal
595 Confusional State 146 1.9 1.9 no signal
596 Femur Fracture 28 1.9 1.9 no signal
597 Red Blood Cell Sedimentation Rate Increased 10 1.9 1.9 no signal
598 Candida Infection 15 1.9 1.9 no signal
599 Anal Incontinence 8 1.9 1.9 no signal
600 Pharyngeal Oedema 14 1.9 1.9 no signal
601 Hypotonia 9 1.9 1.9 no signal
602 Nerve Injury 10 1.9 1.9 no signal
603 Retching 19 1.9 1.9 no signal
604 Erectile Dysfunction 23 1.9 1.9 no signal
605 Hunger 12 1.9 1.9 no signal
606 Blood Urine Present 17 1.9 1.9 no signal
607 Intestinal Perforation 10 1.9 1.9 no signal
608 Rhabdomyolysis 37 1.9 1.9 no signal
609 Arthritis 70 1.8 1.9 no signal
610 Throat Tightness 24 1.8 1.9 no signal
611 Dry Eye 43 1.8 1.9 no signal
612 Blood Calcium Decreased 10 1.8 1.8 no signal
613 Rhinorrhoea 57 1.8 1.8 no signal
614 Tooth Extraction 11 1.8 1.8 no signal
615 Chronic Obstructive Pulmonary Disease 46 1.8 1.8 no signal
616 Eye Discharge 9 1.8 1.8 no signal
617 Body Temperature Increased 18 1.8 1.8 no signal
618 Mood Swings 28 1.8 1.8 no signal
619 Crying 32 1.8 1.8 no signal
620 Exostosis 8 1.8 1.8 no signal
621 Neutrophil Count Increased 9 1.8 1.8 no signal
622 Muscle Atrophy 11 1.8 1.8 no signal
623 Blister 49 1.8 1.8 no signal
624 Emotional Disorder 27 1.8 1.8 no signal
625 Dysphagia 82 1.8 1.8 no signal
626 Asthma 97 1.8 1.8 no signal
627 Pain In Extremity 255 1.8 1.8 no signal
628 Abnormal Dreams 24 1.8 1.8 no signal
629 Pain 531 1.8 1.8 no signal
630 Foetal Exposure During Pregnancy 70 1.8 1.8 no signal
631 Hallucination, Visual 18 1.8 1.8 no signal
632 Disorientation 34 1.8 1.8 no signal
633 Splenomegaly 10 1.8 1.8 no signal
634 General Physical Health Deterioration 98 1.8 1.8 no signal
635 Haematocrit Decreased 17 1.8 1.8 no signal
636 Tooth Disorder 19 1.8 1.8 no signal
637 Throat Irritation 38 1.8 1.8 no signal
638 Squamous Cell Carcinoma 8 1.8 1.8 no signal
639 Accidental Overdose 31 1.8 1.8 no signal
640 Lymphocyte Count Decreased 15 1.8 1.8 no signal
641 Sputum Discoloured 8 1.8 1.8 no signal
642 Drug Withdrawal Syndrome 75 1.8 1.8 no signal
643 Coagulopathy 14 1.8 1.8 no signal
644 Dysmenorrhoea 11 1.8 1.8 no signal
645 Neuroleptic Malignant Syndrome 10 1.8 1.8 no signal
646 Feeling Jittery 16 1.7 1.7 no signal
647 Hypercholesterolaemia 8 1.7 1.7 no signal
648 Gout 15 1.7 1.7 no signal
649 Aspiration 9 1.7 1.7 no signal
650 Condition Aggravated 250 1.7 1.7 no signal
651 Localised Infection 20 1.7 1.7 no signal
652 Face Oedema 14 1.7 1.7 no signal
653 Fluid Retention 42 1.7 1.7 no signal
654 Knee Operation 8 1.7 1.7 no signal
655 Dizziness 410 1.7 1.7 no signal
656 Oesophagitis 9 1.7 1.7 no signal
657 Ear Pain 16 1.7 1.7 no signal
658 Hot Flush 62 1.7 1.7 no signal
659 Heart Rate Decreased 29 1.7 1.7 no signal
660 Circulatory Collapse 14 1.7 1.7 no signal
661 Amnesia 53 1.7 1.7 no signal
662 Blood Glucose Abnormal 15 1.7 1.7 no signal
663 Hypokalaemia 37 1.7 1.7 no signal
664 Sneezing 18 1.7 1.7 no signal
665 Swollen Tongue 25 1.7 1.7 no signal
666 Erythema 164 1.7 1.7 no signal
667 Transient Ischaemic Attack 27 1.7 1.7 no signal
668 Activities Of Daily Living Impaired 16 1.7 1.7 no signal
669 Deep Vein Thrombosis 52 1.7 1.7 no signal
670 Central Nervous System Lesion 11 1.7 1.7 no signal
671 Pancreatitis 42 1.7 1.7 no signal
672 Oedema Peripheral 97 1.7 1.7 no signal
673 Cellulitis 40 1.7 1.7 no signal
674 Ear Infection 21 1.6 1.6 no signal
675 Headache 495 1.6 1.7 no signal
676 Abdominal Discomfort 132 1.6 1.7 no signal
677 Fatigue 613 1.6 1.7 no signal
678 Feeling Cold 22 1.6 1.6 no signal
679 Sluggishness 8 1.6 1.6 no signal
680 Hypoaesthesia 118 1.6 1.6 no signal
681 Asthenia 296 1.6 1.7 no signal
682 Ventricular Tachycardia 13 1.6 1.6 no signal
683 Therapy Cessation 40 1.6 1.6 no signal
684 Gallbladder Disorder 14 1.6 1.6 no signal
685 Mydriasis 10 1.6 1.6 no signal
686 Psychomotor Hyperactivity 13 1.6 1.6 no signal
687 Dehydration 104 1.6 1.6 no signal
688 Rash Pruritic 42 1.6 1.6 no signal
689 Oedema 42 1.6 1.6 no signal
690 Limb Discomfort 24 1.6 1.6 no signal
691 Delusion 12 1.6 1.6 no signal
692 Muscular Weakness 88 1.6 1.6 no signal
693 Abdominal Pain 180 1.6 1.6 no signal
694 Hypotension 155 1.6 1.6 no signal
695 Hyperkalaemia 27 1.6 1.6 no signal
696 Ill-defined Disorder 47 1.6 1.6 no signal
697 Neuropathy Peripheral 73 1.6 1.6 no signal
698 Oral Herpes 15 1.6 1.6 no signal
699 Myalgia 131 1.6 1.6 no signal
700 Ventricular Extrasystoles 8 1.6 1.6 no signal
701 Petechiae 8 1.6 1.6 no signal
702 Basal Cell Carcinoma 12 1.6 1.6 no signal
703 Tooth Loss 16 1.6 1.6 no signal
704 Impaired Quality Of Life 11 1.6 1.6 no signal
705 Dyspnoea 432 1.6 1.6 no signal
706 Blood Alkaline Phosphatase Increased 19 1.6 1.6 no signal
707 Muscle Spasms 140 1.6 1.6 no signal
708 Conjunctivitis 14 1.6 1.6 no signal
709 Bone Disorder 14 1.6 1.6 no signal
710 Intentional Product Use Issue 67 1.6 1.6 no signal
711 Hepatic Failure 23 1.6 1.6 no signal
712 Gastrointestinal Disorder 67 1.6 1.6 no signal
713 Extrapyramidal Disorder 19 1.6 1.6 no signal
714 Cholecystitis 9 1.6 1.6 no signal
715 Pleural Effusion 46 1.6 1.6 no signal
716 Gastroenteritis 11 1.6 1.6 no signal
717 Pulmonary Embolism 72 1.6 1.6 no signal
718 Sepsis 84 1.6 1.6 no signal
719 Oxygen Saturation Decreased 42 1.6 1.6 no signal
720 Abscess 12 1.6 1.6 no signal
721 Palpitations 88 1.6 1.6 no signal
722 Adrenal Insufficiency 9 1.6 1.6 no signal
723 Haemoptysis 21 1.6 1.6 no signal
724 Hypersensitivity 139 1.6 1.6 no signal
725 Product Use In Unapproved Indication 183 1.6 1.6 no signal
726 Hypophagia 19 1.6 1.6 no signal
727 Joint Range Of Motion Decreased 10 1.6 1.6 no signal
728 Deformity 7 1.6 1.6 no signal
729 Fluid Overload 11 1.6 1.6 no signal
730 Hypoxia 26 1.5 1.5 no signal
731 Alopecia 145 1.5 1.5 no signal
732 Ocular Discomfort 8 1.5 1.5 no signal
733 Pneumonia 238 1.5 1.5 no signal
734 Lacrimation Increased 22 1.5 1.5 no signal
735 Skin Ulcer 19 1.5 1.5 no signal
736 Influenza 82 1.5 1.5 no signal
737 Product Packaging Quantity Issue 8 1.5 1.5 no signal
738 Dysuria 27 1.5 1.5 no signal
739 Generalised Oedema 9 1.5 1.5 no signal
740 Irritability 44 1.5 1.5 no signal
741 Herpes Zoster 42 1.5 1.5 no signal
742 Secretion Discharge 9 1.5 1.5 no signal
743 Balance Disorder 63 1.5 1.5 no signal
744 Hernia 14 1.5 1.5 no signal
745 Blood Glucose Decreased 35 1.5 1.5 no signal
746 Cough 203 1.5 1.5 no signal
747 Affect Lability 7 1.5 1.5 no signal
748 Delirium 25 1.5 1.5 no signal
749 Nausea 570 1.5 1.5 no signal
750 Skin Exfoliation 60 1.5 1.5 no signal
751 Hypoglycaemia 35 1.5 1.5 no signal
752 Rectal Haemorrhage 31 1.5 1.5 no signal
753 Blood Creatine Phosphokinase Increased 21 1.5 1.5 no signal
754 Decreased Immune Responsiveness 7 1.5 1.5 no signal
755 Decreased Appetite 165 1.5 1.5 no signal
756 Product Use Complaint 11 1.5 1.5 no signal
757 Infection 102 1.5 1.5 no signal
758 Arthralgia 293 1.5 1.5 no signal
759 Drug Dependence 115 1.5 1.5 no signal
760 Heart Rate Irregular 16 1.5 1.5 no signal
761 Abdominal Distension 73 1.5 1.5 no signal
762 Haemoglobin Decreased 72 1.5 1.5 no signal
763 Upper Limb Fracture 14 1.5 1.5 no signal
764 Internal Haemorrhage 8 1.5 1.5 no signal
765 Diarrhoea 449 1.5 1.5 no signal
766 Blood Potassium Decreased 21 1.5 1.5 no signal
767 Contraindicated Product Administered 21 1.4 1.4 no signal
768 Malaise 306 1.4 1.5 no signal
769 Paralysis 10 1.4 1.4 no signal
770 Pericardial Effusion 16 1.4 1.4 no signal
771 Intentional Dose Omission 19 1.4 1.4 no signal
772 Injection Site Induration 9 1.4 1.4 no signal
773 Vertigo 42 1.4 1.4 no signal
774 Psoriasis 90 1.4 1.4 no signal
775 Respiratory Distress 19 1.4 1.4 no signal
776 Product Prescribing Issue 14 1.4 1.4 no signal
777 Anaemia 131 1.4 1.4 no signal
778 Drug Dose Omission 115 1.4 1.4 no signal
779 Bedridden 9 1.4 1.4 no signal
780 Post Procedural Haemorrhage 8 1.4 1.4 no signal
781 Paraesthesia 108 1.4 1.4 no signal
782 Chest Pain 127 1.4 1.4 no signal
783 Mental Status Changes 19 1.4 1.4 no signal
784 Sensory Disturbance 11 1.4 1.4 no signal
785 Acute Respiratory Failure 13 1.4 1.4 no signal
786 Lymphadenopathy 24 1.4 1.4 no signal
787 Vomiting 317 1.4 1.4 no signal
788 Skin Discolouration 31 1.4 1.4 no signal
789 Insurance Issue 10 1.4 1.4 no signal
790 Therapy Non-responder 30 1.4 1.4 no signal
791 Dysphonia 39 1.4 1.4 no signal
792 Blood Pressure Fluctuation 16 1.4 1.4 no signal
793 Therapeutic Product Effect Incomplete 47 1.4 1.4 no signal
794 Product Dose Omission 44 1.4 1.4 no signal
795 Presyncope 16 1.4 1.4 no signal
796 Aphasia 20 1.4 1.4 no signal
797 Stomatitis 40 1.4 1.4 no signal
798 Exposure During Pregnancy 41 1.4 1.4 no signal
799 Vision Blurred 90 1.4 1.4 no signal
800 Schizophrenia 8 1.4 1.4 no signal
801 Liver Function Test Increased 14 1.4 1.4 no signal
802 Mobility Decreased 47 1.4 1.4 no signal
803 Inappropriate Schedule Of Product Administration 116 1.4 1.4 no signal
804 Respiratory Tract Infection 17 1.4 1.4 no signal
805 Diplopia 17 1.4 1.4 no signal
806 Decreased Activity 7 1.4 1.4 no signal
807 Urosepsis 6 1.4 1.4 no signal
808 Taste Disorder 13 1.4 1.4 no signal
809 Drug-induced Liver Injury 20 1.3 1.4 no signal
810 Body Height Decreased 7 1.3 1.3 no signal
811 Chest Discomfort 66 1.3 1.3 no signal
812 Tendon Rupture 8 1.3 1.3 no signal
813 Multiple Sclerosis 31 1.3 1.3 no signal
814 Treatment Noncompliance 35 1.3 1.3 no signal
815 Influenza Like Illness 53 1.3 1.3 no signal
816 Flank Pain 6 1.3 1.3 no signal
817 Coordination Abnormal 9 1.3 1.3 no signal
818 Increased Appetite 12 1.3 1.3 no signal
819 Rash 276 1.3 1.3 no signal
820 Hair Colour Changes 8 1.3 1.3 no signal
821 Hypocalcaemia 12 1.3 1.3 no signal
822 Skin Fissures 12 1.3 1.3 no signal
823 Tooth Fracture 7 1.3 1.3 no signal
824 Drug Intolerance 61 1.3 1.3 no signal
825 Hyperglycaemia 23 1.3 1.3 no signal
826 Expired Product Administered 21 1.3 1.3 no signal
827 Therapeutic Product Effect Decreased 28 1.3 1.3 no signal
828 Transaminases Increased 14 1.3 1.3 no signal
829 Eosinophilia 11 1.3 1.3 no signal
830 Haematemesis 16 1.3 1.3 no signal
831 Respiratory Tract Congestion 10 1.3 1.3 no signal
832 Drug Resistance 16 1.3 1.3 no signal
833 Intestinal Obstruction 23 1.3 1.3 no signal
834 Speech Disorder 32 1.3 1.3 no signal
835 Neoplasm 7 1.3 1.3 no signal
836 Blood Pressure Abnormal 12 1.3 1.3 no signal
837 Sinus Disorder 12 1.3 1.3 no signal
838 Chills 71 1.3 1.3 no signal
839 Convulsion 35 1.3 1.3 no signal
840 Hepatic Enzyme Increased 41 1.3 1.3 no signal
841 Spinal Pain 7 1.2 1.2 no signal
842 Bone Pain 35 1.2 1.2 no signal
843 Glycosylated Haemoglobin Increased 15 1.2 1.2 no signal
844 Incorrect Route Of Product Administration 10 1.2 1.2 no signal
845 Agranulocytosis 11 1.2 1.2 no signal
846 Haemorrhage 62 1.2 1.2 no signal
847 Eye Irritation 33 1.2 1.2 no signal
848 Macular Degeneration 7 1.2 1.2 no signal
849 Musculoskeletal Pain 31 1.2 1.2 no signal
850 Ear Discomfort 6 1.2 1.2 no signal
851 Visual Impairment 72 1.2 1.2 no signal
852 Atrial Fibrillation 57 1.2 1.2 no signal
853 Poor Venous Access 6 1.2 1.2 no signal
854 Rash Papular 13 1.2 1.2 no signal
855 Oral Pain 13 1.2 1.2 no signal
856 Chromaturia 13 1.2 1.2 no signal
857 Aphonia 8 1.2 1.2 no signal
858 Psoriatic Arthropathy 23 1.2 1.2 no signal
859 Transfusion 6 1.2 1.2 no signal
860 Multi-organ Failure 10 1.2 1.2 no signal
861 Blood Test Abnormal 8 1.2 1.2 no signal
862 Injection Site Mass 21 1.2 1.2 no signal
863 Head Discomfort 10 1.2 1.2 no signal
864 Drug Ineffective 746 1.2 1.2 no signal
865 Therapy Interrupted 39 1.2 1.2 no signal
866 Ulcer 9 1.2 1.2 no signal
867 Diabetes Mellitus Inadequate Control 10 1.2 1.2 no signal
868 Dysgeusia 42 1.2 1.2 no signal
869 Eating Disorder 12 1.2 1.2 no signal
870 Injection Site Rash 17 1.2 1.2 no signal
871 Off Label Use 486 1.2 1.2 no signal
872 Drug Hypersensitivity 108 1.2 1.2 no signal
873 Infusion Site Pain 7 1.1 1.1 no signal
874 Cardiac Failure 44 1.1 1.1 no signal
875 Eye Pruritus 18 1.1 1.1 no signal
876 Application Site Pain 12 1.1 1.1 no signal
877 Nervous System Disorder 17 1.1 1.1 no signal
878 Wrong Technique In Drug Usage Process 20 1.1 1.1 no signal
879 Increased Tendency To Bruise 5 1.1 1.1 no signal
880 Appendicitis 5 1.1 1.1 no signal
881 Eye Infection 6 1.1 1.1 no signal
882 Surgery 31 1.1 1.1 no signal
883 Skin Burning Sensation 38 1.1 1.1 no signal
884 Product Dose Omission Issue 152 1.1 1.1 no signal
885 Epistaxis 40 1.1 1.1 no signal
886 Fistula 6 1.1 1.1 no signal
887 Pyrexia 184 1.1 1.1 no signal
888 Colitis 20 1.1 1.1 no signal
889 Premature Baby 16 1.1 1.1 no signal
890 Complication Associated With Device 7 1.1 1.1 no signal
891 Knee Arthroplasty 11 1.1 1.1 no signal
892 Bone Loss 8 1.1 1.1 no signal
893 Needle Issue 15 1.1 1.1 no signal
894 Pulmonary Fibrosis 10 1.1 1.1 no signal
895 Musculoskeletal Disorder 10 1.1 1.1 no signal
896 Hair Texture Abnormal 7 1.1 1.1 no signal
897 Eye Disorder 17 1.1 1.1 no signal
898 Sinus Bradycardia 5 1.1 1.1 no signal
899 Tendonitis 8 1.1 1.1 no signal
900 Drug Administration Error 16 1.1 1.1 no signal
901 Renal Disorder 24 1.1 1.1 no signal
902 Madarosis 6 1.1 1.1 no signal
903 Lung Disorder 25 1.1 1.1 no signal
904 Injection Site Erythema 63 1.1 1.1 no signal
905 Coeliac Disease 5 1.1 1.1 no signal
906 Local Swelling 9 1.1 1.1 no signal
907 Inability To Afford Medication 5 1.1 1.1 no signal
908 Inflammatory Bowel Disease 5 1.1 1.1 no signal
909 Peripheral Coldness 7 1.1 1.1 no signal
910 Hepatitis 13 1.1 1.1 no signal
911 Clostridium Difficile Infection 11 1.1 1.1 no signal
912 Application Site Rash 7 1.1 1.1 no signal
913 Procedural Pain 14 1.1 1.1 no signal
914 Product Substitution Issue 29 1.0 1.0 no signal
915 Cerebral Haemorrhage 18 1.0 1.0 no signal
916 Oral Discomfort 7 1.0 1.0 no signal
917 Musculoskeletal Stiffness 44 1.0 1.0 no signal
918 Spinal Fracture 10 1.0 1.0 no signal
919 Wrong Technique In Product Usage Process 101 1.0 1.0 no signal
920 Blood Pressure Decreased 33 1.0 1.0 no signal
921 Gamma-glutamyltransferase Increased 11 1.0 1.0 no signal
922 Intentional Self-injury 10 1.0 1.0 no signal
923 Rash Generalised 13 1.0 1.0 no signal
924 Injection Site Bruising 39 1.0 1.0 no signal
925 Respiratory Failure 36 1.0 1.0 no signal
926 Dry Throat 5 1.0 1.0 no signal
927 Cardiac Disorder 46 1.0 1.0 no signal
928 Subarachnoid Haemorrhage 5 1.0 1.0 no signal
929 Libido Decreased 6 1.0 1.0 no signal
930 Folliculitis 5 1.0 1.0 no signal
931 Hepatic Cirrhosis 9 1.0 1.0 no signal
932 Dermatitis Allergic 6 1.0 1.0 no signal
933 Abasia 12 1.0 1.0 no signal
934 Mouth Ulceration 10 1.0 1.0 no signal
935 Blood Urea Increased 8 1.0 1.0 no signal
936 Blood Creatinine Increased 31 1.0 1.0 no signal
937 Dry Skin 62 1.0 1.0 no signal
938 Flushing 48 1.0 1.0 no signal
939 White Blood Cell Count Decreased 51 1.0 1.0 no signal
940 Joint Swelling 56 1.0 1.0 no signal
941 Multiple Sclerosis Relapse 32 1.0 1.0 no signal
942 Drug Effect Incomplete 17 1.0 1.0 no signal
943 Gastric Disorder 16 1.0 1.0 no signal
944 Skin Irritation 21 1.0 1.0 no signal
945 Gait Inability 15 0.9 0.9 no signal
946 Rash Maculo-papular 10 0.9 0.9 no signal
947 Product Administration Error 9 0.9 0.9 no signal
948 Eye Haemorrhage 6 0.9 0.9 no signal
949 Injection Site Pain 136 0.9 0.9 no signal
950 Thrombosis 36 0.9 0.9 no signal
951 Incorrect Dose Administered 100 0.9 0.9 no signal
952 Lung Infection 7 0.9 0.9 no signal
953 Renal Failure Acute 19 0.9 0.9 no signal
954 Disease Recurrence 21 0.9 0.9 no signal
955 Gingival Bleeding 6 0.9 0.9 no signal
956 Shock 10 0.9 0.9 no signal
957 Coronary Artery Occlusion 6 0.9 0.9 no signal
958 Plasma Cell Myeloma 17 0.9 0.9 no signal
959 Abdominal Pain Lower 11 0.9 0.9 no signal
960 Blood Thyroid Stimulating Hormone Increased 4 0.9 0.9 no signal
961 Device Defective 7 0.9 0.9 no signal
962 Medication Error 24 0.9 0.9 no signal
963 Ovarian Cancer 4 0.9 0.9 no signal
964 Product Packaging Issue 4 0.9 0.9 no signal
965 Death 370 0.9 0.9 no signal
966 Gastrointestinal Haemorrhage 36 0.9 0.9 no signal
967 Extra Dose Administered 17 0.9 0.9 no signal
968 Blindness Unilateral 6 0.9 0.9 no signal
969 Systemic Lupus Erythematosus 15 0.9 0.9 no signal
970 Eye Inflammation 4 0.9 0.9 no signal
971 Cerebrovascular Accident 72 0.9 0.9 no signal
972 Alanine Aminotransferase Increased 26 0.9 0.9 no signal
973 Platelet Count Decreased 45 0.9 0.9 no signal
974 Osteonecrosis 14 0.9 0.9 no signal
975 Amenorrhoea 7 0.9 0.9 no signal
976 Skin Cancer 9 0.9 0.9 no signal
977 Eye Pain 23 0.9 0.9 no signal
978 Myocardial Infarction 73 0.9 0.9 no signal
979 Glaucoma 8 0.9 0.9 no signal
980 Upper Gastrointestinal Haemorrhage 7 0.9 0.9 no signal
981 Pulmonary Arterial Hypertension 6 0.9 0.9 no signal
982 Liver Function Test Abnormal 12 0.9 0.9 no signal
983 Pain Of Skin 11 0.8 0.8 no signal
984 Hospice Care 4 0.8 0.8 no signal
985 No Therapeutic Response 5 0.8 0.8 no signal
986 Pallor 11 0.8 0.8 no signal
987 Glossodynia 9 0.8 0.8 no signal
988 Inappropriate Schedule Of Drug Administration 29 0.8 0.8 no signal
989 Covid-19 71 0.8 0.8 no signal
990 Osteonecrosis Of Jaw 10 0.8 0.8 no signal
991 Prescribed Underdose 8 0.8 0.8 no signal
992 Vaginal Discharge 4 0.8 0.8 no signal
993 Application Site Pruritus 9 0.8 0.8 no signal
994 Injection Site Swelling 30 0.8 0.8 no signal
995 Renal Impairment 33 0.8 0.8 no signal
996 Hospitalisation 60 0.8 0.8 no signal
997 Injection Site Reaction 27 0.8 0.8 no signal
998 Eyelid Ptosis 4 0.8 0.8 no signal
999 Helicobacter Infection 4 0.8 0.8 no signal
1000 Blood Glucose Increased 74 0.8 0.8 no signal
1001 Drug Level Decreased 4 0.8 0.8 no signal
1002 Visual Acuity Reduced 13 0.8 0.8 no signal
1003 Pelvic Pain 7 0.8 0.8 no signal
1004 No Adverse Event 68 0.8 0.8 no signal
1005 Cardiac Failure Congestive 31 0.8 0.8 no signal
1006 International Normalised Ratio Increased 11 0.8 0.8 no signal
1007 Deafness 10 0.8 0.8 no signal
1008 Colitis Ulcerative 17 0.8 0.8 no signal
1009 Menstruation Irregular 10 0.8 0.8 no signal
1010 Aspartate Aminotransferase Increased 20 0.8 0.8 no signal
1011 Hip Fracture 12 0.8 0.8 no signal
1012 Breast Cancer Metastatic 4 0.8 0.8 no signal
1013 Malignant Melanoma 5 0.8 0.8 no signal
1014 Product Dose Omission In Error 10 0.8 0.8 no signal
1015 Product Taste Abnormal 5 0.8 0.8 no signal
1016 Acute Myocardial Infarction 11 0.8 0.8 no signal
1017 Injection Site Urticaria 9 0.8 0.8 no signal
1018 Uveitis 5 0.8 0.8 no signal
1019 Blood Bilirubin Increased 10 0.8 0.8 no signal
1020 Acne 28 0.8 0.8 no signal
1021 Injection Site Nodule 4 0.8 0.8 no signal
1022 Prostatic Specific Antigen Increased 5 0.8 0.8 no signal
1023 Epilepsy 11 0.7 0.7 no signal
1024 Ageusia 9 0.7 0.7 no signal
1025 Dementia 10 0.7 0.7 no signal
1026 Stevens-johnson Syndrome 8 0.7 0.7 no signal
1027 Multiple Organ Dysfunction Syndrome 10 0.7 0.7 no signal
1028 Product Physical Issue 7 0.7 0.7 no signal
1029 Drug Effect Decreased 19 0.7 0.7 no signal
1030 Device Use Issue 6 0.7 0.7 no signal
1031 Hyperthyroidism 5 0.7 0.7 no signal
1032 Injection Site Pruritus 23 0.7 0.7 no signal
1033 Anosmia 5 0.7 0.7 no signal
1034 Underdose 25 0.7 0.7 no signal
1035 Bone Marrow Failure 7 0.7 0.7 no signal
1036 Injection Site Haematoma 5 0.7 0.7 no signal
1037 Ascites 10 0.7 0.7 no signal
1038 Product Preparation Error 7 0.7 0.7 no signal
1039 Rheumatoid Arthritis 38 0.7 0.7 no signal
1040 Muscle Rigidity 4 0.7 0.7 no signal
1041 Product Quality Issue 45 0.7 0.7 no signal
1042 Jaundice 9 0.7 0.7 no signal
1043 Product Use Issue 62 0.7 0.7 no signal
1044 Brain Neoplasm 3 0.7 0.7 no signal
1045 Hypoacusis 14 0.7 0.7 no signal
1046 Drug Dispensing Error 5 0.7 0.7 no signal
1047 Lymphoma 5 0.7 0.7 no signal
1048 Application Site Irritation 4 0.7 0.7 no signal
1049 Ocular Hyperaemia 15 0.7 0.7 no signal
1050 Liver Disorder 14 0.7 0.7 no signal
1051 Posterior Reversible Encephalopathy Syndrome 3 0.7 0.7 no signal
1052 Injection Site Haemorrhage 25 0.7 0.7 no signal
1053 Adverse Event 29 0.7 0.7 no signal
1054 Adverse Drug Reaction 28 0.7 0.7 no signal
1055 Anaphylactic Shock 8 0.6 0.6 no signal
1056 Sleep Disorder Due To A General Medical Condition 5 0.6 0.6 no signal
1057 Sars-cov-2 Test Positive 4 0.6 0.6 no signal
1058 Palmar-plantar Erythrodysaesthesia Syndrome 7 0.6 0.6 no signal
1059 Sopor 4 0.6 0.6 no signal
1060 Ovarian Cyst 3 0.6 0.6 no signal
1061 Incorrect Product Administration Duration 6 0.6 0.6 no signal
1062 Drug Toxicity 4 0.6 0.6 no signal
1063 Device Occlusion 4 0.6 0.6 no signal
1064 Skeletal Injury 3 0.6 0.6 no signal
1065 Drug Effect Less Than Expected 4 0.6 0.6 no signal
1066 Vaginal Haemorrhage 12 0.6 0.6 no signal
1067 Drug Reaction With Eosinophilia And Systemic Symptoms 7 0.6 0.6 no signal
1068 Laboratory Test Abnormal 8 0.6 0.6 no signal
1069 Blindness 11 0.6 0.6 no signal
1070 Device Delivery System Issue 7 0.6 0.6 no signal
1071 Maternal Exposure During Pregnancy 23 0.5 0.5 no signal
1072 Breast Cancer Female 7 0.5 0.5 no signal
1073 Neoplasm Malignant 17 0.5 0.5 no signal
1074 Pancytopenia 14 0.5 0.5 no signal
1075 Diabetic Ketoacidosis 6 0.5 0.5 no signal
1076 Lactic Acidosis 8 0.5 0.5 no signal
1077 Incorrect Route Of Drug Administration 9 0.5 0.5 no signal
1078 Thyroid Cancer 3 0.5 0.5 no signal
1079 Incorrect Drug Administration Duration 7 0.5 0.5 no signal
1080 Injection Site Warmth 5 0.5 0.5 no signal
1081 Device Issue 21 0.5 0.5 no signal
1082 Cytomegalovirus Infection 4 0.5 0.5 no signal
1083 Abnormal Weight Gain 3 0.5 0.5 no signal
1084 Injection Site Irritation 3 0.5 0.5 no signal
1085 Septic Shock 10 0.5 0.5 no signal
1086 Device Breakage 9 0.5 0.5 no signal
1087 Malignant Neoplasm Progression 23 0.5 0.5 no signal
1088 Abortion Spontaneous 9 0.5 0.5 no signal
1089 Device Malfunction 15 0.5 0.5 no signal
1090 Leukopenia 11 0.5 0.5 no signal
1091 Product Administered At Inappropriate Site 4 0.5 0.5 no signal
1092 Thrombocytopenia 24 0.4 0.4 no signal
1093 Neutropenia 29 0.4 0.4 no signal
1094 Disease Progression 24 0.4 0.4 no signal
1095 Neutrophil Count Decreased 8 0.4 0.4 no signal
1096 Incorrect Dose Administered By Device 5 0.4 0.4 no signal
1097 Infusion Related Reaction 13 0.4 0.4 no signal
1098 Breast Cancer 18 0.4 0.4 no signal
1099 Application Site Erythema 5 0.4 0.4 no signal
1100 Sickle Cell Anaemia With Crisis 3 0.4 0.4 no signal
1101 Premature Delivery 3 0.4 0.4 no signal
1102 Bladder Cancer 11 0.4 0.4 no signal
1103 Device Dislocation 8 0.4 0.4 no signal
1104 Exposure Via Skin Contact 4 0.4 0.4 no signal
1105 Febrile Neutropenia 11 0.3 0.3 no signal
1106 Gynaecomastia 5 0.3 0.3 no signal
1107 Pharmaceutical Product Complaint 4 0.3 0.3 no signal
1108 Device Use Error 5 0.3 0.3 no signal
1109 Product Adhesion Issue 5 0.3 0.3 no signal
1110 Accidental Exposure To Product 14 0.3 0.3 no signal
1111 Drug Effective For Unapproved Indication 4 0.3 0.3 no signal
1112 Product Storage Error 11 0.3 0.3 no signal
1113 Dependence 6 0.2 0.2 no signal
1114 Drug Dose Omission By Device 8 0.2 0.2 no signal
1115 Pancreatic Carcinoma 3 0.2 0.2 no signal
1116 Prostate Cancer 8 0.2 0.2 no signal
1117 Device Leakage 4 0.2 0.2 no signal
1118 Drug Exposure During Pregnancy 3 0.2 0.2 no signal
1119 Device Difficult To Use 5 0.2 0.2 no signal
1120 Renal Cancer 3 0.1 0.1 no signal
1121 Device Expulsion 3 0.1 0.1 no signal