Reaction

Chronic Spontaneous Urticaria reporting signals

Last recalculated 2026-09-14T18:28:35.993900+00:00 · 1,088 reports · 39 co-occurring drugs

As of the last recalculation, Chronic Spontaneous Urticaria appears in 1,088 FAERS reports alongside 39 co-occurring drug terms. The strongest observed disproportionality signal is OMALIZUMAB (PRR 420.0).

Important: FAERS is a spontaneous, voluntary, unverified reporting system. PRR and ROR identify reporting patterns for investigation; they are not incidence rates and do not establish causation.

Drug	Co-reports	PRR	ROR
Omalizumab	689	420.0	423.4
Cetirizine Hydrochloride Allergy	125	89.1	89.4
Cetirizine Hydrochloride Tablets	125	89.1	89.4
Doxepin Hydrochloride	46	72.7	73.0
Doxepin	32	62.2	62.4
Cetirizine	202	60.9	61.1
Daspone	25	50.2	50.4
Dapsone Gel, 5%	25	50.2	50.3
Dapsone	25	45.8	45.9
Hydroxyzine	102	45.0	45.1
Cetiirizine	88	43.2	43.2
Montelukast	157	41.7	41.7
Desloratadine	22	40.0	40.1
Terbinafine Hydrochloride	18	39.4	39.5
Fexofenadine Hcl	17	35.7	35.8
Cyclosporine	172	34.9	35.0
Cetirizine Hydrochloride	216	31.0	31.1
Fexofenadine	25	29.6	29.6
Loratadine Tablet	76	29.1	29.1
Montelukast Sodium	155	28.2	28.3
Tofacitinib Citrate	17	25.2	25.2
Mometasone	23	24.5	24.5
Cefazolin	10	21.2	21.2
Anakinra	17	19.9	19.9
Loratadine	99	19.3	19.3
Daptomycin	9	18.8	18.8
Diphenhydramine Hydrochloride	138	18.1	18.1
Candesartan	32	17.7	17.7
Fexofenadine Hydrochloride	19	17.0	17.0
Heparin Sodium	12	16.9	16.9
Rosuvastatin Calcium	24	16.6	16.7
Crisaborole	8	16.1	16.1
Cefazolin Sodium	10	16.0	16.0
Hydroxyzine Hydrochloride	9	13.2	13.2
Hydroxyzine Hydrochloride Oral	9	13.2	13.2
Tramadol Hydrochloride	21	10.9	10.9
Entecavir	5	8.2	8.2
Ranitidine	58	5.8	5.8
Dupilumab	56	2.3	2.3

Related reactions

Data source: openFDA FAERS. See the OpenPV methodology and limitations.